prednisone has been researched along with Airway Remodeling in 2 studies
Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.
Airway Remodeling: The structural changes in the number, mass, size and/or composition of the airway tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fifty severe asthmatics received prednisone 40 mg/d for 2 weeks and maintenance therapy with budesonide/formoterol 400/12 μg twice daily + budesonide/formoterol 200/6 μg as needed for 12 weeks." | 3.88 | Airway pathology in severe asthma is related to airflow obstruction but not symptom control. ( Annoni, R; Araújo-Paulino, BB; Buttignol, M; Carvalho-Pinto, RM; Cukier, A; Del Frari, HS; Dolhnikoff, M; Ferreira, DS; Gregório, MG; Katayama, EH; Mauad, T; Oliveira, BL; Rabe, KF; Stelmach, R; Teles, AM, 2018) |
| "Asthma is characterized by airway remodeling." | 1.62 | Glucocorticoid induced transcript 1 represses airway remodeling of asthmatic mouse via inhibiting IL-13/periostin/TGF-β1 signaling. ( Kuang, J; Wang, W; Xun, Q; Yang, Q; Zhu, G, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xun, Q | 1 |
| Kuang, J | 1 |
| Yang, Q | 1 |
| Wang, W | 1 |
| Zhu, G | 1 |
| Ferreira, DS | 1 |
| Carvalho-Pinto, RM | 1 |
| Gregório, MG | 1 |
| Annoni, R | 1 |
| Teles, AM | 1 |
| Buttignol, M | 1 |
| Araújo-Paulino, BB | 1 |
| Katayama, EH | 1 |
| Oliveira, BL | 1 |
| Del Frari, HS | 1 |
| Cukier, A | 1 |
| Dolhnikoff, M | 1 |
| Stelmach, R | 1 |
| Rabe, KF | 1 |
| Mauad, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Brazilian Severe Asthma Cohort Follow up: Clinical, Inflammatory and Functional Evaluation of a Population of Severe Asthmatics Based in Possible Phenotypes and Pathophysiologic Study of Obesity Association[NCT03532685] | 110 participants (Anticipated) | Interventional | 2018-05-31 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for prednisone and Airway Remodeling
| Article | Year |
|---|---|
Glucocorticoid induced transcript 1 represses airway remodeling of asthmatic mouse via inhibiting IL-13/periostin/TGF-β1 signaling.
Topics: Airway Remodeling; Aluminum Hydroxide; Animals; Asthma; Cell Adhesion Molecules; Disease Models, Ani | 2021 |
Airway pathology in severe asthma is related to airflow obstruction but not symptom control.
Topics: Adult; Airway Obstruction; Airway Remodeling; Anti-Asthmatic Agents; Asthma; Bronchi; Budesonide, Fo | 2018 |