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prednisone and Airflow Obstruction, Chronic

prednisone has been researched along with Airflow Obstruction, Chronic in 89 studies

Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.

Research Excerpts

ExcerptRelevanceReference
" Possible predisposing factors included treatment with prednisone pulse therapy for obstructive pulmonary disease and prior polymyalgia rheumatica."7.73[Spontaneous bilateral rupture of the Achilles tendon in an elderly woman undergoing prednisone pulse therapy with a history of polymyalgia rheumatica]. ( de Wolf, MM; Frijns, CJ; van der Krans, A, 2006)
"Systemic inflammation is present in chronic obstructive pulmonary disease (COPD), which has been linked to cardiovascular morbidity and mortality."6.71Effects of fluticasone on systemic markers of inflammation in chronic obstructive pulmonary disease. ( Lacy, P; Man, SF; Sin, DD; York, E, 2004)
"Rhinocerebral mucormycosis is a rapidly progressive and often fatal infection frequently seen in patients with uncontrolled diabetes mellitus and hematologic malignancies."5.34Rhinocerebral mucormycosis acquired after a short course of prednisone therapy. ( Ferguson, AD, 2007)
"We present a patient with prednisone-induced spinal epidural lipomatosis (SEL) and relatively acute neurologic deterioration followed by rapid recovery after surgical decompression."4.91Severity of presentation is associated with time to recovery in spinal epidural lipomatosis. ( D'Amico, R; Ellis, JA; Kennedy, BC; Mandigo, CE; Praver, M, 2015)
"A 66-year-old woman developed severe hyponatremia after receiving moxifloxacin for five days for treatment of COPD exacerbation."3.78Syndrome of inappropriate antidiuretic hormone associated with moxifloxacin. ( Eraly, SA; Yam, FK, 2012)
" In Spain, however, a HIV-negative man with a history of chronic obstructive pulmonary disease and prednisone treatment was recently hospitalized because of hypotension and asthenia."3.73Fatal visceral leishmaniasis, with massive bone-marrow infection, in an immunosuppressed but HIV-negative Spanish patient, after the initiation of treatment with meglumine antimoniate. ( Garcia-Cordoba, F; Gonzalez Diaz, G; Ortuño, FJ; Segovia, M, 2005)
" Possible predisposing factors included treatment with prednisone pulse therapy for obstructive pulmonary disease and prior polymyalgia rheumatica."3.73[Spontaneous bilateral rupture of the Achilles tendon in an elderly woman undergoing prednisone pulse therapy with a history of polymyalgia rheumatica]. ( de Wolf, MM; Frijns, CJ; van der Krans, A, 2006)
"Chronic obstructive pulmonary disease (COPD) is a major public health issue affecting approximately 4% to 7% of the Swiss population."2.90Reduction of corticosteroid use in outpatient treatment of exacerbated COPD - Study protocol for a randomized, double-blind, non-inferiority study, (The RECUT-trial). ( Abig, K; Bachler, H; Boesing, M; Cattaneo, M; Dieterle, T; Essig, S; Leuppi, JD; Markun, S; Merlo, C; Rutishauser, J; Schuurmans, MM; Senn, O; Ullmer, E; Urwyler, P; Zeller, A, 2019)
"The prednisone cohort was registered at clinicalTrials."2.90Effect of short-term oral prednisone therapy on blood gene expression: a randomised controlled clinical trial. ( Chen, V; FitzGerald, JM; Hollander, Z; McManus, BM; Ng, RT; Obeidat, M; Sin, DD; Takiguchi, H, 2019)
"Treatment with dapagliflozin was safe and there was no difference in risk of hypoglycaemia compared with placebo."2.87Dapagliflozin for prednisone-induced hyperglycaemia in acute exacerbation of chronic obstructive pulmonary disease. ( Brandjes, DPM; Gerards, MC; Gerdes, VEA; Hageman, IMG; Hoekstra, JBL; Kross, M; Patberg, KW; Potter van Loon, BJ; Snijders, D; Venema, GE; Vriesendorp, TM, 2018)
"Of 314 patients with AECOPD randomised to 5 or 14 days of prednisone treatment, 311 were included in the analysis."2.84Predictors of re-exacerbation after an index exacerbation of chronic obstructive pulmonary disease in the REDUCE randomised clinical trial. ( Engel, B; Leuppi, JD; Rutishauser, J; Schindler, C, 2017)
"30 patients presenting to ED with AECOPD were included."2.80Intravenous magnesium sulphate as an adjuvant therapy in acute exacerbations of chronic obstructive pulmonary disease: a single centre, randomised, double-blinded, parallel group, placebo-controlled trial: a pilot study. ( Armstrong, P; Clayton-Smith, B; Hardy, M; Marchant, G; Marsh, E; Mukerji, S; Shahpuri, B; Smith, N, 2015)
"Prednisone was stopped abruptly, irrespective of the test results."2.80Prospective analysis of adrenal function in patients with acute exacerbations of COPD: the Reduction in the Use of Corticosteroids in Exacerbated COPD (REDUCE) trial. ( Bingisser, R; Bodmer, M; Briel, M; Drescher, T; Duerring, U; Henzen, C; Leibbrandt, Y; Leuppi, JD; Maier, S; Miedinger, D; Mueller, B; Rutishauser, J; Scherr, A; Schindler, C; Schuetz, P; Stoeckli, R; Tamm, M; Viatte, S; von Garnier, C, 2015)
"Patients hospitalized for COPD in the past year."2.77A comprehensive care management program to prevent chronic obstructive pulmonary disease hospitalizations: a randomized, controlled trial. ( Adams, SG; Bourbeau, J; Colling, C; Fan, VS; Fiore, L; Gaziano, JM; Huang, GD; Leatherman, S; Lew, R; Liang, MH; Mador, MJ; Mazzuca, SA; Niewoehner, DE; Panos, RJ; Rastogi, P; Robbins, R; Sarosi, G; Shannon, C; Sharafkhaneh, A; Sriram, PS; Stoller, JK; Thwin, SS; Wagner, TH, 2012)
"With prednisone, there was a net increase of 13 m in 6MWD (P = 0."2.74Predicting corticosteroid response in chronic obstructive pulmonary disease using exhaled nitric oxide. ( Condliffe, R; Cook, JM; Cowan, JO; Dummer, JF; Epton, MJ; Landhuis, CE; Smith, AD; Taylor, DR, 2009)
"In patients with COPD and CAP, the time courses over 7 days of PCT and CRP showed a nearly parallel decline compared to non-COPD patients with CAP."2.73Influence of steroids on procalcitonin and C-reactive protein in patients with COPD and community-acquired pneumonia. ( Capelli, B; Cerutti, B; Domenighetti, G; Duchini, F; Lepori, M; Perren, A; Senn, V, 2008)
"Patients with severe COPD (stages III-IV, classification of the Global Initiative for Chronic Obstructive Lung Disease) and incapacitating dyspnea (scores 3-5, Medical Research Council [MRC] scale) were randomized to a control or domiciliary rehabilitation group."2.73[Benefits of a home-based pulmonary rehabilitation program for patients with severe chronic obstructive pulmonary disease]. ( Casan Clarà, P; Gáldiz, JB; Gorostiza, A; Güell Rous, R; López de Santa María, E; Regiane Resqueti, V, 2007)
"Participants were 159 patients with COPD randomized by general practice site into control or intervention groups."2.72Self-management plans in the primary care of patients with chronic obstructive pulmonary disease. ( Cook, JM; Dowson, CA; Epton, MJ; Frampton, CM; McCartin, FJ; McGeoch, GR; Town, GI; Willsman, KJ, 2006)
"Systemic inflammation is present in chronic obstructive pulmonary disease (COPD), which has been linked to cardiovascular morbidity and mortality."2.71Effects of fluticasone on systemic markers of inflammation in chronic obstructive pulmonary disease. ( Lacy, P; Man, SF; Sin, DD; York, E, 2004)
"Of 36 moderate to severe COPD patients started on prednisone, 30 completed the study according to the protocol."2.71Time to spirometric and exercise response in 4-week oral corticosteroid trial for stable COPD patients. ( Bolliger, CT; Botha, P; Richter, DC; Schuurmans, MM; Steyn, D, 2005)
"Acute exacerbations of chronic obstructive pulmonary disease (COPD)--characterized by shortness of breath, increased sputum production, increased purulence, or a combination of these signs--are costly and can have major impacts on the patient's health."2.53Treating and preventing acute exacerbations of COPD. ( Aboussouan, LS; Hatipoglu, US, 2016)
"In patients with exacerbations of chronic obstructive pulmonary disease (COPD) requiring hospitalisation, 5 days of corticosteroid therapy appears to be as effective as 14 days of corticosteroid therapy for preventing recurrences."2.50COPD exacerbations: 5 days of corticosteroid therapy. ( , 2014)
"COPD is the 5th leading cause of death in the United States."2.44Steroid allergy? A case report and review of the literature. ( Danley, SG, 2007)
"Prednisone was the most frequently implicated corticosteroid, but cases involving ACTH, cortisone, and high-dose inhaled dexamethasone and beclomethasone were also identified."2.44Drug dependence involving prednisone: two cases and a review of the literature. ( Anfinson, TJ; Channappa, C; Vo, HT, 2008)
" However, the most appropriate dosage regimen remains controversial, as the corticosteroid regimens used in these trials differed greatly, and no studies have directly compared medium-, high-, and low-dose regimens."2.43Is there an optimal corticosteroid regimen for the management of an acute exacerbation of chronic obstructive pulmonary disease? ( Hemstreet, BA; Vondracek, SF, 2006)
"In elderly subjects with COPD, CAT were associated significantly with the risk of COPD exacerbation, with PNI also a potential predictor."1.91Prognostic Nutritional Index (PNI) as a Potential Prognostic Tool for Exacerbation of COPD in Elderly Patients. ( Anazawa, R; Ikari, J; Kawata, N; Sato, H; Shiko, Y; Shimada, A; Suzuki, E; Suzuki, M; Suzuki, T; Tatsumi, K; Yamamoto, M, 2023)
"Patients with a history of chronic obstructive pulmonary disease (COPD) or asthma undergoing surgery are at risk for developing postoperative pulmonary complications, associated with morbidity and mortality."1.72[Dutch guideline to prevent perioperative pulmonal complications: how is the adherence?] ( Bronsveld, I; Kappen, T; Marsman, M; Miggelbrink, LA; Senff, JR; van Klei, W; van Waes, JAR, 2022)
"A multifaceted stewardship intervention significantly reduced steroid dosing in hospitalized AECOPD patients."1.72A multifaceted stewardship intervention helps curb steroid overprescribing in hospitalized patients with acute exacerbations of COPD. ( Cole, JL; Smith, SE, 2022)
"Initial dosing ranged from 40 to 625 mg/day with only four responders (13%) selecting 40 mg/day."1.56Provider perceptions on steroid dosing in AECOPD: Laying the groundwork for steroid stewardship. ( Cole, JL; Smith, S, 2020)
"Effective inpatient chronic obstructive pulmonary disease (COPD) exacerbation management is critical to appropriately manage health care resources."1.51Systemic Corticosteroid and Antibiotic Use in Hospitalized Patients With Chronic Obstructive Pulmonary Disease Exacerbation. ( Murphy, JA; Petite, SE, 2019)
"Our EHS-based "COPD PowerPlan" order set included admission, laboratory, pharmacy, and radiology orders for managing AECOPD."1.48The use of a standardized order set reduces systemic corticosteroid dose and length of stay for individuals hospitalized with acute exacerbations of COPD: a cohort study. ( Bhatt, SP; Davison, PN; Dransfield, MT; Gulati, S; Kalehoff, JP; Kirkpatrick, DP; Wells, JM; Wren, CS; Zouk, AN, 2018)
" Secondary outcome measures were corticosteroid dosage during the entire hospitalization, length of stay, hospital follow-up rates, and 30-day readmission rates."1.40Improving adherence for management of acute exacerbation of chronic obstructive pulmonary disease. ( Clark, C; Seidensticker, S; Sharma, G; Sonstein, L; Zeng, L, 2014)
"ABPA in COPD is uncommon, but early identification and initiation of systemic corticosteroid therapy can lead to improvement in symptoms and prognosis."1.39[Allergic bronchopulmonary aspergillosis in patients with chronic obstructive pulmonary disease: report of 3 cases]. ( Jin, JM; Li, R; Liu, XF; Liu, Y; Sun, YC, 2013)
"Smartphone-based collection of COPD symptom diaries enables near-complete identification of exacerbations at inception."1.39Detection of COPD Exacerbations and compliance with patient-reported daily symptom diaries using a smart phone-based information system [corrected]. ( Coyle, PV; de Verdier, MG; Higenbottam, T; Hussack, P; Jenkins, M; Johnston, NW; Lambert, K; Lewis, J; McIvor, RA; Newbold, P; Norman, GR, 2013)
"We analyzed COPD subjects with GOLD I-IV disease in the COPDGene® study."1.38Demographic, physiologic and radiographic characteristics of COPD patients taking chronic systemic corticosteroids. ( Criner, GJ; Kim, V; Make, BJ; Murphy, JR; Newell, J; Satti, A; Silverman, EK; Steiner, RM; Swift, I; Wilson, C, 2012)
"Severe COPD is associated with increased levels of HDL-C, which is partially attributable to oral steroid use."1.37Advanced chronic obstructive pulmonary disease is associated with high levels of high-density lipoprotein cholesterol. ( DeFilippis, A; Eberlein, M; Girgis, RE; Iacono, A; Jones, S; Reed, RM, 2011)
"A common extrapulmonary effect to chronic obstructive pulmonary disease (COPD) is osteoporosis."1.36Screening, prevention and treatment of osteoporosis in patients with chronic obstructive pulmonary disease - a population-based database study. ( Brixen, K; Hallas, J; Madsen, H, 2010)
"Rhinocerebral mucormycosis is a rapidly progressive and often fatal infection frequently seen in patients with uncontrolled diabetes mellitus and hematologic malignancies."1.34Rhinocerebral mucormycosis acquired after a short course of prednisone therapy. ( Ferguson, AD, 2007)
"Acute exacerbation of COPD (AE-COPD) is a major problem influencing patient outcome, increasing both economic burden and mortality."1.33[Cost analysis for inpatient therapy for patients with acute exacerbations of chronic obstructive pulmonary disease]. ( Kida, K; Motegi, T; Yamada, K, 2006)
"Treatment with prednisone did not influence the levels of IL-8."1.32Decreased levels of myeloperoxidase in induced sputum of patients with COPD after treatment with oral glucocorticoids. ( Barczyk, A; Pierzchala, W; Sozañska, E; Trzaska, M, 2004)
"A 69-year-old man with chronic obstructive pulmonary disease (COPD) presented with an exacerbation of cough and breathlessness, as well as a 5 day history of sudden-onset bilateral calf tenderness."1.31Spontaneous bilateral rupture of the Achilles tendon in a patient with chronic obstructive pulmonary disease. ( Horsley, M; Khurana, R; Mahoney, J; Torzillo, PJ, 2002)

Research

Studies (89)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's35 (39.33)29.6817
2010's44 (49.44)24.3611
2020's10 (11.24)2.80

Authors

AuthorsStudies
Kaviani, A1
Khansari Nejad, N1
Akour, A1
AlMuhaissen, SA1
Nusair, MB1
Al-Tammemi, AB1
Mahmoud, NN1
Jalouqa, S1
Alrawashdeh, MN1
Shanahan, JP1
Moore, CM1
Kampf, JW1
Szymczak, NK1
Guo, J1
Wang, H1
Luo, Y1
An, H1
Zhang, Z2
Liu, G1
Li, J1
Metcalfe, GD1
Smith, TW1
Hippler, M1
Ayala Izurieta, JE1
Márquez, CO1
García, VJ1
Jara Santillán, CA1
Sisti, JM1
Pasqualotto, N1
Van Wittenberghe, S1
Delegido, J1
Kubo, Y1
Kitagawa, Y1
Miyazaki, T1
Sohda, M1
Yamaji, T1
Sakai, M1
Saeki, H1
Nemoto, K1
Oyama, T2
Muto, M1
Takeuchi, H1
Toh, Y1
Matsubara, H1
Mano, M1
Kono, K1
Kato, K1
Yoshida, M1
Kawakubo, H1
Booka, E1
Yamatsuji, T1
Kato, H1
Ito, Y1
Ishikawa, H1
Ishihara, R1
Tsushima, T1
Kawachi, H1
Kojima, T1
Kuribayashi, S1
Makino, T1
Matsuda, S1
Doki, Y1
Ma, P1
Tang, X1
Zhang, L2
Wang, X1
Wang, W1
Zhang, X1
Wang, S2
Zhou, N1
Dodd, J1
Jordan, R1
Makhlina, M1
Pesco Koplowitz, L1
Koplowitz, B1
Barnett, K1
Yang, WH1
Spana, C1
Buchanan, SW1
Mafa-Attoye, T1
Dunfield, K1
Thevathasan, NV1
Isaac, ME1
Wu, X2
Huang, JW1
Su, BK1
Yuan, L1
Zheng, WQ1
Zhang, H2
Zheng, YX1
Zhu, W1
Chou, PT1
Manso, AP1
De Morais, DC1
Yamamoto, K1
Owen, G1
de Carvalho, RM1
Palma-Dibb, RG1
Brown, JC1
Yang, S1
Mire, EF1
Miele, L1
Ochoa, A1
Zabaleta, J1
Katzmarzyk, PT1
Moi, CT1
Bhowmick, S1
Qureshi, M1
Wang, K1
Feng, B1
Yang, Y1
Chen, Y1
Wang, Y2
Yang, L1
Jiang, K1
James, TD1
Chaturvedi, V1
Postiglione, WM1
Chakraborty, RD1
Yu, B1
Tabiś, W1
Hameed, S1
Biniskos, N1
Jacobson, A1
Zhou, H1
Greven, M1
Ferry, VE1
Leighton, C1
Wu, F1
Lei, H1
Chen, G1
Chen, C1
Song, Y1
Cao, Z1
Zhang, C2
Zhou, J1
Lu, Y1
Pappone, C1
Santinelli, V1
Mecarocci, V1
Tondi, L1
Ciconte, G1
Manguso, F1
Sturla, F1
Vicedomini, G1
Micaglio, E1
Anastasia, L1
Pica, S1
Camporeale, A1
Lombardi, M1
Shieh, PB1
Elfring, G1
Trifillis, P1
Santos, C1
Peltz, SW1
Parsons, JA1
Apkon, S1
Darras, BT1
Campbell, C1
McDonald, CM1
Galaviz, KI1
Shah, NS1
Gutierrez, M1
Collins, LF1
Lahiri, CD1
Moran, CA1
Szabo, B1
Sumitani, J1
Rhodes, J1
Marconi, VC1
Nguyen, ML1
Cantos, VD1
Armstrong, WS1
Colasanti, JA1
Cole, JL2
Smith, SE1
Miggelbrink, LA1
Marsman, M1
Senff, JR1
van Waes, JAR1
Bronsveld, I1
van Klei, W1
Kappen, T1
Suzuki, E1
Kawata, N1
Shimada, A1
Sato, H1
Anazawa, R1
Suzuki, M1
Shiko, Y1
Yamamoto, M1
Ikari, J1
Tatsumi, K1
Suzuki, T1
Urwyler, P1
Boesing, M1
Abig, K1
Cattaneo, M1
Dieterle, T1
Zeller, A1
Bachler, H1
Markun, S1
Senn, O1
Merlo, C1
Essig, S1
Ullmer, E1
Rutishauser, J4
Schuurmans, MM2
Leuppi, JD4
Smith, S1
George, J1
Ganoff, M1
Lipari, M1
Dameron, M1
Horowitz, M1
Gupta, N1
Abi Hatem, N1
Chuzi, S1
Kuang, F1
Khan, SS1
Chong, WH1
Ibrahim, A1
Saha, BK1
Singh, AD1
Mian, A1
Stoller, JK2
McCann, J1
Teare, K1
Cochard, E1
Toney, B1
Engel, B1
Schindler, C3
Gerards, MC1
Venema, GE1
Patberg, KW1
Kross, M1
Potter van Loon, BJ1
Hageman, IMG1
Snijders, D2
Brandjes, DPM1
Hoekstra, JBL1
Vriesendorp, TM1
Gerdes, VEA1
Gulati, S1
Zouk, AN1
Kalehoff, JP1
Wren, CS1
Davison, PN1
Kirkpatrick, DP1
Bhatt, SP1
Dransfield, MT1
Wells, JM1
Petite, SE1
Murphy, JA1
Mahajan, KR1
Tacoronte Pérez, S1
Cerón Navarro, J1
Pastor Colom, A1
Morcillo Aixelá, A1
Ricciuti, B1
Dahlberg, SE1
Adeni, A1
Sholl, LM1
Nishino, M1
Awad, MM1
Takiguchi, H1
Chen, V1
Obeidat, M1
Hollander, Z1
FitzGerald, JM2
McManus, BM1
Ng, RT1
Sin, DD4
Crespo-Lessmann, A1
Torrego-Fernández, A1
Johnston, NW1
Lambert, K1
Hussack, P1
de Verdier, MG1
Higenbottam, T1
Lewis, J1
Newbold, P1
Jenkins, M1
Norman, GR1
Coyle, PV1
McIvor, RA2
Schuetz, P3
Bingisser, R2
Bodmer, M2
Briel, M2
Drescher, T2
Duerring, U2
Henzen, C2
Leibbrandt, Y2
Maier, S2
Miedinger, D2
Müller, B2
Scherr, A2
Stoeckli, R2
Viatte, S2
von Garnier, C2
Tamm, M2
Park, HY1
Abroug, F1
Ouanes-Besbes, L1
Fkih-Hassen, M1
Ouanes, I1
Ayed, S1
Dachraoui, F1
Brochard, L1
Elatrous, S1
Schuster, S1
Diethelm, M1
Steurer, J1
Neuvians, T1
Maselli, DJ1
Peters, JI1
Sethi, S2
Nag, N1
Liu, XF1
Sun, YC1
Jin, JM1
Li, R1
Liu, Y1
Asher, GN1
Mounsey, A1
Tikotekar, A1
Jagpal, S1
Nagella, N1
Similowski, T1
Suissa, S1
Sonstein, L1
Clark, C1
Seidensticker, S1
Zeng, L1
Sharma, G1
Mueller, B1
Praver, M1
Kennedy, BC1
Ellis, JA1
D'Amico, R1
Mandigo, CE1
Mukerji, S1
Shahpuri, B1
Clayton-Smith, B1
Smith, N1
Armstrong, P1
Hardy, M1
Marchant, G1
Marsh, E1
Hatipoglu, US1
Aboussouan, LS1
Patel, KP1
Vaidya, A1
Gibson, CJ1
Henrich, TJ1
Lyons, JL1
Martinez, FJ1
Rabe, KF1
Ferguson, GT1
Fabbri, LM1
Rennard, S1
Feldman, GJ1
Spangenthal, S1
Gottschlich, GM1
Rodriguez-Roisin, R1
Arora, S1
Siler, TM1
Siddiqui, S1
Darken, P1
Fischer, T1
Maes, A1
Golden, M1
Orevillo, C1
Reisner, C1
Cerceo, E1
Kotloff, RM1
Hadjiliadis, D1
Ahya, VN1
Pochettino, A1
Gillespie, C1
Christie, JD1
Dummer, JF1
Epton, MJ2
Cowan, JO1
Cook, JM2
Condliffe, R1
Landhuis, CE1
Smith, AD1
Taylor, DR1
Daniels, JM1
de Graaff, CS1
Vlaspolder, F1
Jansen, HM1
Boersma, WG1
Marchand, E1
Madsen, H1
Brixen, K1
Hallas, J1
Bugano, DD1
Campos, SV1
Afonso, JE1
Caramori, ML1
Teixeira, RH1
Carraro, RM1
Strabelli, TM1
Machado, CM1
Samano, MN1
Pêgo-Fernandes, P1
Jatene, FB1
Bischoff, EW1
Hamd, DH1
Sedeno, M1
Benedetti, A1
Schermer, TR1
Bernard, S1
Maltais, F2
Bourbeau, J3
Reed, RM1
Iacono, A1
DeFilippis, A1
Eberlein, M1
Girgis, RE1
Jones, S1
Yam, FK1
Eraly, SA1
Swift, I1
Satti, A1
Kim, V1
Make, BJ1
Newell, J1
Steiner, RM1
Wilson, C1
Murphy, JR1
Silverman, EK1
Criner, GJ1
Fan, VS1
Gaziano, JM1
Lew, R1
Adams, SG1
Leatherman, S1
Thwin, SS1
Huang, GD1
Robbins, R1
Sriram, PS1
Sharafkhaneh, A1
Mador, MJ1
Sarosi, G1
Panos, RJ1
Rastogi, P1
Wagner, TH1
Mazzuca, SA1
Shannon, C1
Colling, C1
Liang, MH1
Fiore, L1
Niewoehner, DE2
Garber, K1
Aaron, SD2
Vandemheen, KL2
Field, SK1
Marciniuk, DD1
Nair, P1
Mallick, R1
Hebert, P1
Dales, R1
Stiell, IG1
Ahuja, J1
Dickinson, G1
Brison, R1
Rowe, BH1
Dreyer, J1
Yetisir, E1
Cass, D1
Wells, G1
Irwin, RS1
Madison, JM1
Motta, AC1
Arruda, D1
Souza, CS1
Foss, NT1
Busti, AJ1
Vervan, MD1
Brouse, SD1
Hurst, JR1
Donaldson, GC1
Wedzicha, JA1
Salloum, A1
Elbaage, TY1
Soubani, AO1
Rolla, G1
Bucca, C1
Courtney, AU1
McDiarmid, T1
Mackler, L1
Briscoe, D1
McDiarmuid, T1
Lacy, P1
York, E1
Man, SF1
Barczyk, A1
Sozañska, E1
Trzaska, M1
Pierzchala, W1
Broseghini, C1
Testi, R1
Polese, G1
Tosatto, R1
Rossi, A1
Garcia-Cordoba, F1
Ortuño, FJ1
Segovia, M1
Gonzalez Diaz, G1
Feldstein, AC1
Elmer, PJ1
Nichols, GA1
Herson, M1
Couëtil, LL1
Chilcoat, CD1
DeNicola, DB1
Clark, SP1
Glickman, NW1
Glickman, LT1
Cai, M1
Chen, H1
Wang, XD1
Zhang, HY1
Botha, P1
Steyn, D1
Richter, DC1
Bolliger, CT1
Vondracek, SF1
Hemstreet, BA1
Carranza González, R1
Tena Gómez, D1
Prieto Gómez, E1
Barberá Farré, JR1
Fernández Cenjor, J1
Valeyre, D1
Lebargy, F1
McGeoch, GR1
Willsman, KJ1
Dowson, CA1
Town, GI1
Frampton, CM1
McCartin, FJ1
de Wolf, MM1
van der Krans, A1
Frijns, CJ1
Motegi, T1
Yamada, K1
Kida, K1
Danley, SG1
Regiane Resqueti, V1
Gorostiza, A1
Gáldiz, JB1
López de Santa María, E1
Casan Clarà, P1
Güell Rous, R1
Ferguson, AD1
Manteca, A1
Pelaez, AI1
del Mar Garcia-Suarez, M1
Hidalgo, E1
del Busto, B1
Mendez, FJ1
Christ-Crain, M1
Schild, U1
Süess, E1
Facompre, M1
Baty, F1
Nusbaumer, C1
Brutsche, M1
Perren, A1
Cerutti, B1
Lepori, M1
Senn, V1
Capelli, B1
Duchini, F1
Domenighetti, G1
Anfinson, TJ1
Channappa, C1
Vo, HT1
Khurana, R1
Torzillo, PJ1
Horsley, M1
Mahoney, J1

Clinical Trials (13)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
"Reduction of Corticosteroid Use in Outpatient Treatment of Exacerbated COPD - a Randomized, Double-blind, Non-inferiority Study (The RECUT-Trial)"[NCT02386735]470 participants (Anticipated)Interventional2015-03-31Recruiting
Clinical Implementation and Outcomes Evaluation of Blood-Based Biomarkers for COPD Management: COPD Prednisone Sub-Study[NCT02534402]Phase 440 participants (Actual)Interventional2015-08-31Active, not recruiting
Clinical Implementation and Outcomes Evaluation of Blood-Based Biomarkers for Chronic Obstructive Pulmonary Disease Management[NCT02050022]522 participants (Actual)Observational2013-04-30Active, not recruiting
Personalized Variable Versus Fixed Dose Corticosteroids Therapy in Hospitalized Patients With Acute Exacerbations of Chronic Obstructive Pulmonary Disease[NCT02147015]248 participants (Actual)Interventional2014-06-30Completed
The Value of Antibiotic Treatment of Exacerbations of Hospitalised COPD Patients[NCT00170222]Phase 4258 participants (Anticipated)Interventional2002-07-31Completed
CRP-guided Antibiotic Treatment in Patients Hospitalized With Acute Exacerbations of COPD Patients. A Randomized Controlled Intervention Trial.[NCT01232140]220 participants (Anticipated)Interventional2011-07-31Recruiting
A Prospective Baseline Assessment of the Risk of Osteoporosis in Patients With Chronic Obstructive Lung Disease and Outcomes After 2 Years; a Pilot Study[NCT01161680]30 participants (Actual)Observational2010-07-31Completed
Impact of Telemedicine in the Rate of Readmission for COPD and Cost-effectiveness Analysis (e- Pneumo ) : Project CRONEX 3.0[NCT03505138]120 participants (Actual)Interventional2018-05-01Completed
Adaptive Computerized COPD Exacerbation Self-management Support (ACCESS): A Randomized Controlled Trial[NCT02553096]87 participants (Actual)Interventional2015-06-30Active, not recruiting
CSP #560 - Bronchitis and Emphysema Advice and Training to Reduce Hospitalization (BREATH)[NCT00395083]Phase 2426 participants (Actual)Interventional2006-07-31Terminated (stopped due to The DMC detected an imbalance in safety outcomes between the two groups.)
Breathlessness Perception in COPD: Relationship With Exacerbation Frequency[NCT02113839]34 participants (Actual)Interventional2014-04-30Completed
TNF-alpha Antagonists for Acute Exacerbations of COPD: A Randomized, Double-Blind, Placebo-Controlled Pilot Trial[NCT00789997]Phase 2/Phase 381 participants (Actual)Interventional2008-11-30Completed
Effects of Fluticasone On Systemic Markers of Inflammation in Chronic Obstructive Pulmonary Disease[NCT00175565]Phase 450 participants Interventional2002-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Hospitalization-free Survival - Time to Event

(NCT00395083)
Timeframe: From randomization until date of first hospitalization for COPD, assessed up to 26 months

Interventionyears (Median)
Usual Care0.45
Comprehensive Care Management Program0.46

Time to All-Cause Death

(NCT00395083)
Timeframe: From randomization until death, assessed up to 26 months

Interventionyears (Median)
Usual Care0.51
Comprehensive Care Management Program0.49

Hazard Ratio for All-Cause Mortality

(NCT00395083)
Timeframe: 26 months

,
Interventionparticipants (Number)
All-Cause DeathAlive
Comprehensive Care Management Program28181
Usual Care10207

Hazard Ratio for First COPD Hospitalization

(NCT00395083)
Timeframe: 26 months

,
Interventionparticipants (Number)
Subjects with COPD HospitalizationSubjects without COPD Hospitalization
Comprehensive Care Management Program36173
Usual Care34183

Change in Lung Function (Forced Expiratory Volume in 1 Second (FEV1)

"FEV1 was obtained using calibrated spirometers at approximately the same time of day at all visits throughout the study. The highest acceptable FEV1 and the highest FVC measurement each obtained on any of three blows (even if not from the same curve) meeting the American Thoracic Society criteria constituted the data for that test set.~Not all participants had Day 14 FEV1 measures collected" (NCT00789997)
Timeframe: Day 0 to Day 14

Interventionpercentage of change in FEV1 (Mean)
Etanercept15.2
Prednisone20.1

Number of Participants With Treatment Failure by 90 Days Assignment

In the etanercept group 16/40 (40%) failed treatment compared with 12/38 (32%) in the prednisone group. (NCT00789997)
Timeframe: Day 0 to Day 90

Interventionparticipants (Number)
Etanercept16
Prednisone12

Reviews

10 reviews available for prednisone and Airflow Obstruction, Chronic

ArticleYear
    Biomaterial investigations in dentistry, 2021, Volume: 8, Issue:1

    Topics: Adult; Alcohol Drinking; Ammonia; Animals; Anti-Inflammatory Agents; Area Under Curve; B-Lymphocytes

2021
COPD exacerbations: 5 days of corticosteroid therapy.
    Prescrire international, 2014, Volume: 23, Issue:153

    Topics: Administration, Intravenous; Administration, Oral; Adrenal Cortex Hormones; Disease Progression; Dru

2014
Severity of presentation is associated with time to recovery in spinal epidural lipomatosis.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2015, Volume: 22, Issue:8

    Topics: Anti-Inflammatory Agents; Diabetes Mellitus, Type 2; Epidural Space; Female; Humans; Lipomatosis; Mi

2015
Treating and preventing acute exacerbations of COPD.
    Cleveland Clinic journal of medicine, 2016, Volume: 83, Issue:4

    Topics: Acidosis, Respiratory; Acute Disease; Administration, Inhalation; Albuterol; Anti-Bacterial Agents;

2016
[Long-term trials assessing pharmacological treatments in COPD: lessons and limitations].
    Revue des maladies respiratoires, 2010, Volume: 27, Issue:2

    Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adult; Aged; Albuterol; Androstadienes; Broncho

2010
Clinical inquiries. Do systemic corticosteroids lessen symptoms in acute exacerbations of COPD?
    The Journal of family practice, 2003, Volume: 52, Issue:12

    Topics: Administration, Oral; Adrenal Cortex Hormones; Evidence-Based Medicine; Glucocorticoids; Humans; Pre

2003
The role of systemic corticosteroids in acute exacerbation of chronic obstructive pulmonary disease.
    American journal of respiratory medicine : drugs, devices, and other interventions, 2002, Volume: 1, Issue:4

    Topics: Acute Disease; Administration, Oral; Adrenal Cortex Hormones; Drug Administration Schedule; Humans;

2002
Is there an optimal corticosteroid regimen for the management of an acute exacerbation of chronic obstructive pulmonary disease?
    Pharmacotherapy, 2006, Volume: 26, Issue:4

    Topics: Acute Disease; Clinical Trials as Topic; Drug Administration Schedule; Glucocorticoids; Humans; Pred

2006
Steroid allergy? A case report and review of the literature.
    The Journal of the Oklahoma State Medical Association, 2007, Volume: 100, Issue:1

    Topics: Asthma; Drug Hypersensitivity; Glucocorticoids; Humans; Prednisone; Pulmonary Disease, Chronic Obstr

2007
Drug dependence involving prednisone: two cases and a review of the literature.
    Psychopharmacology bulletin, 2008, Volume: 41, Issue:1

    Topics: Adult; Female; Humans; Hypothalamo-Hypophyseal System; Male; Middle Aged; Pituitary-Adrenal System;

2008

Trials

23 trials available for prednisone and Airflow Obstruction, Chronic

ArticleYear
Reduction of corticosteroid use in outpatient treatment of exacerbated COPD - Study protocol for a randomized, double-blind, non-inferiority study, (The RECUT-trial).
    Trials, 2019, Dec-16, Volume: 20, Issue:1

    Topics: Administration, Oral; Adrenal Cortex Hormones; Ambulatory Care; Disease Progression; Double-Blind Me

2019
Predictors of re-exacerbation after an index exacerbation of chronic obstructive pulmonary disease in the REDUCE randomised clinical trial.
    Swiss medical weekly, 2017, Volume: 147

    Topics: Aged; Anti-Bacterial Agents; Cohort Studies; Disease Progression; Dyspnea; Female; Glucocorticoids;

2017
Dapagliflozin for prednisone-induced hyperglycaemia in acute exacerbation of chronic obstructive pulmonary disease.
    Diabetes, obesity & metabolism, 2018, Volume: 20, Issue:5

    Topics: Aged; Benzhydryl Compounds; Combined Modality Therapy; Diabetes Mellitus, Type 2; Double-Blind Metho

2018
Effect of short-term oral prednisone therapy on blood gene expression: a randomised controlled clinical trial.
    Respiratory research, 2019, Aug-05, Volume: 20, Issue:1

    Topics: Administration, Oral; Aged; Aged, 80 and over; Drug Administration Schedule; Female; Gene Expression

2019
Effect of short-term oral prednisone therapy on blood gene expression: a randomised controlled clinical trial.
    Respiratory research, 2019, Aug-05, Volume: 20, Issue:1

    Topics: Administration, Oral; Aged; Aged, 80 and over; Drug Administration Schedule; Female; Gene Expression

2019
Effect of short-term oral prednisone therapy on blood gene expression: a randomised controlled clinical trial.
    Respiratory research, 2019, Aug-05, Volume: 20, Issue:1

    Topics: Administration, Oral; Aged; Aged, 80 and over; Drug Administration Schedule; Female; Gene Expression

2019
Effect of short-term oral prednisone therapy on blood gene expression: a randomised controlled clinical trial.
    Respiratory research, 2019, Aug-05, Volume: 20, Issue:1

    Topics: Administration, Oral; Aged; Aged, 80 and over; Drug Administration Schedule; Female; Gene Expression

2019
Short-term vs conventional glucocorticoid therapy in acute exacerbations of chronic obstructive pulmonary disease: the REDUCE randomized clinical trial.
    JAMA, 2013, Jun-05, Volume: 309, Issue:21

    Topics: Acute Disease; Aged; Disease Progression; Double-Blind Method; Female; Glucocorticoids; Humans; Male

2013
Short-term vs conventional glucocorticoid therapy in acute exacerbations of chronic obstructive pulmonary disease: the REDUCE randomized clinical trial.
    JAMA, 2013, Jun-05, Volume: 309, Issue:21

    Topics: Acute Disease; Aged; Disease Progression; Double-Blind Method; Female; Glucocorticoids; Humans; Male

2013
Short-term vs conventional glucocorticoid therapy in acute exacerbations of chronic obstructive pulmonary disease: the REDUCE randomized clinical trial.
    JAMA, 2013, Jun-05, Volume: 309, Issue:21

    Topics: Acute Disease; Aged; Disease Progression; Double-Blind Method; Female; Glucocorticoids; Humans; Male

2013
Short-term vs conventional glucocorticoid therapy in acute exacerbations of chronic obstructive pulmonary disease: the REDUCE randomized clinical trial.
    JAMA, 2013, Jun-05, Volume: 309, Issue:21

    Topics: Acute Disease; Aged; Disease Progression; Double-Blind Method; Female; Glucocorticoids; Humans; Male

2013
Prednisone in COPD exacerbation requiring ventilatory support: an open-label randomised evaluation.
    The European respiratory journal, 2014, Volume: 43, Issue:3

    Topics: Administration, Oral; Aged; Anti-Inflammatory Agents; Disease Progression; Female; Humans; Hyperglyc

2014
[5 days of systemic steroids in COPD exacerbation are adequate].
    Praxis, 2013, Aug-21, Volume: 102, Issue:17

    Topics: Administration, Oral; Adult; Disease Progression; Drug Administration Schedule; Drug Therapy, Combin

2013
Prospective analysis of adrenal function in patients with acute exacerbations of COPD: the Reduction in the Use of Corticosteroids in Exacerbated COPD (REDUCE) trial.
    European journal of endocrinology, 2015, Volume: 173, Issue:1

    Topics: Adrenal Cortex Function Tests; Adrenal Cortex Hormones; Adrenal Glands; Adrenal Insufficiency; Adren

2015
Intravenous magnesium sulphate as an adjuvant therapy in acute exacerbations of chronic obstructive pulmonary disease: a single centre, randomised, double-blinded, parallel group, placebo-controlled trial: a pilot study.
    The New Zealand medical journal, 2015, Nov-20, Volume: 128, Issue:1425

    Topics: Administration, Inhalation; Administration, Intravenous; Aged; Aged, 80 and over; Albuterol; Broncho

2015
Efficacy and Safety of Glycopyrrolate/Formoterol Metered Dose Inhaler Formulated Using Co-Suspension Delivery Technology in Patients With COPD.
    Chest, 2017, Volume: 151, Issue:2

    Topics: Administration, Inhalation; Adult; Aged; Aged, 80 and over; Bronchodilator Agents; Budesonide; Doubl

2017
Predicting corticosteroid response in chronic obstructive pulmonary disease using exhaled nitric oxide.
    American journal of respiratory and critical care medicine, 2009, Nov-01, Volume: 180, Issue:9

    Topics: Administration, Oral; Adrenal Cortex Hormones; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Cr

2009
Antibiotics in addition to systemic corticosteroids for acute exacerbations of chronic obstructive pulmonary disease.
    American journal of respiratory and critical care medicine, 2010, Jan-15, Volume: 181, Issue:2

    Topics: Acute Disease; Adrenal Cortex Hormones; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial In

2010
Antibiotics in addition to systemic corticosteroids for acute exacerbations of chronic obstructive pulmonary disease.
    American journal of respiratory and critical care medicine, 2010, Jan-15, Volume: 181, Issue:2

    Topics: Acute Disease; Adrenal Cortex Hormones; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial In

2010
Antibiotics in addition to systemic corticosteroids for acute exacerbations of chronic obstructive pulmonary disease.
    American journal of respiratory and critical care medicine, 2010, Jan-15, Volume: 181, Issue:2

    Topics: Acute Disease; Adrenal Cortex Hormones; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial In

2010
Antibiotics in addition to systemic corticosteroids for acute exacerbations of chronic obstructive pulmonary disease.
    American journal of respiratory and critical care medicine, 2010, Jan-15, Volume: 181, Issue:2

    Topics: Acute Disease; Adrenal Cortex Hormones; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial In

2010
Effects of written action plan adherence on COPD exacerbation recovery.
    Thorax, 2011, Volume: 66, Issue:1

    Topics: Aged; Anti-Bacterial Agents; Canada; Delivery of Health Care; Drug Administration Schedule; Drug Pre

2011
Effects of written action plan adherence on COPD exacerbation recovery.
    Thorax, 2011, Volume: 66, Issue:1

    Topics: Aged; Anti-Bacterial Agents; Canada; Delivery of Health Care; Drug Administration Schedule; Drug Pre

2011
Effects of written action plan adherence on COPD exacerbation recovery.
    Thorax, 2011, Volume: 66, Issue:1

    Topics: Aged; Anti-Bacterial Agents; Canada; Delivery of Health Care; Drug Administration Schedule; Drug Pre

2011
Effects of written action plan adherence on COPD exacerbation recovery.
    Thorax, 2011, Volume: 66, Issue:1

    Topics: Aged; Anti-Bacterial Agents; Canada; Delivery of Health Care; Drug Administration Schedule; Drug Pre

2011
A comprehensive care management program to prevent chronic obstructive pulmonary disease hospitalizations: a randomized, controlled trial.
    Annals of internal medicine, 2012, May-15, Volume: 156, Issue:10

    Topics: Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents; Case Management; Cause of Death; Depression;

2012
A comprehensive care management program to prevent chronic obstructive pulmonary disease hospitalizations: a randomized, controlled trial.
    Annals of internal medicine, 2012, May-15, Volume: 156, Issue:10

    Topics: Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents; Case Management; Cause of Death; Depression;

2012
A comprehensive care management program to prevent chronic obstructive pulmonary disease hospitalizations: a randomized, controlled trial.
    Annals of internal medicine, 2012, May-15, Volume: 156, Issue:10

    Topics: Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents; Case Management; Cause of Death; Depression;

2012
A comprehensive care management program to prevent chronic obstructive pulmonary disease hospitalizations: a randomized, controlled trial.
    Annals of internal medicine, 2012, May-15, Volume: 156, Issue:10

    Topics: Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents; Case Management; Cause of Death; Depression;

2012
TNFα antagonists for acute exacerbations of COPD: a randomised double-blind controlled trial.
    Thorax, 2013, Volume: 68, Issue:2

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Disease Progression; Double-Blind Method; Etanercept;

2013
Outpatient oral prednisone after emergency treatment of chronic obstructive pulmonary disease.
    The New England journal of medicine, 2003, Jun-26, Volume: 348, Issue:26

    Topics: Acute Disease; Administration, Oral; Aged; Ambulatory Care; Double-Blind Method; Emergency Treatment

2003
Effects of fluticasone on systemic markers of inflammation in chronic obstructive pulmonary disease.
    American journal of respiratory and critical care medicine, 2004, Oct-01, Volume: 170, Issue:7

    Topics: Administration, Inhalation; Administration, Oral; Aged; Aged, 80 and over; Androstadienes; Anti-Infl

2004
A comparison between inhaled salmeterol and theophylline in the short-term treatment of stable chronic obstructive pulmonary disease.
    Pulmonary pharmacology & therapeutics, 2005, Volume: 18, Issue:2

    Topics: Administration, Inhalation; Aged; Albuterol; Bronchodilator Agents; Cross-Over Studies; Delayed-Acti

2005
Randomized, controlled study of inhaled fluticasone propionate, oral administration of prednisone, and environmental management of horses with recurrent airway obstruction.
    American journal of veterinary research, 2005, Volume: 66, Issue:10

    Topics: Analysis of Variance; Androstadienes; Animals; Bronchoalveolar Lavage; Environment; Fluticasone; Hor

2005
Time to spirometric and exercise response in 4-week oral corticosteroid trial for stable COPD patients.
    Swiss medical weekly, 2005, Sep-17, Volume: 135, Issue:37-38

    Topics: Administration, Oral; Exercise Test; Female; Forced Expiratory Volume; Glucocorticoids; Humans; Male

2005
Self-management plans in the primary care of patients with chronic obstructive pulmonary disease.
    Respirology (Carlton, Vic.), 2006, Volume: 11, Issue:5

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Anxiety; Depression; Female; Glucocorticoids; Humans

2006
[Benefits of a home-based pulmonary rehabilitation program for patients with severe chronic obstructive pulmonary disease].
    Archivos de bronconeumologia, 2007, Volume: 43, Issue:11

    Topics: Aged; Albuterol; Anthropometry; Anti-Inflammatory Agents; Bronchodilator Agents; Female; Home Care S

2007
Influence of steroids on procalcitonin and C-reactive protein in patients with COPD and community-acquired pneumonia.
    Infection, 2008, Volume: 36, Issue:2

    Topics: Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents; C-Reactive Protein; Calcitonin; Calcitonin Ge

2008

Other Studies

56 other studies available for prednisone and Airflow Obstruction, Chronic

ArticleYear
A multifaceted stewardship intervention helps curb steroid overprescribing in hospitalized patients with acute exacerbations of COPD.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2022, 04-01, Volume: 79, Issue:8

    Topics: Adrenal Cortex Hormones; Adult; Humans; Inappropriate Prescribing; Prednisone; Pulmonary Disease, Ch

2022
[Dutch guideline to prevent perioperative pulmonal complications: how is the adherence?]
    Nederlands tijdschrift voor geneeskunde, 2022, 10-20, Volume: 166

    Topics: Adrenal Cortex Hormones; Asthma; Guideline Adherence; Humans; Prednisolone; Prednisone; Pulmonary Di

2022
Prognostic Nutritional Index (PNI) as a Potential Prognostic Tool for Exacerbation of COPD in Elderly Patients.
    International journal of chronic obstructive pulmonary disease, 2023, Volume: 18

    Topics: Aged; Asthma; Humans; Nutrition Assessment; Prednisone; Prognosis; Pulmonary Disease, Chronic Obstru

2023
Provider perceptions on steroid dosing in AECOPD: Laying the groundwork for steroid stewardship.
    The clinical respiratory journal, 2020, Volume: 14, Issue:11

    Topics: Adrenal Cortex Hormones; Emergency Service, Hospital; Humans; Perception; Prednisone; Pulmonary Dise

2020
Corticosteroid Exposure in the Treatment of Severe COPD Exacerbations.
    Journal of pharmacy practice, 2022, Volume: 35, Issue:1

    Topics: Adrenal Cortex Hormones; Disease Progression; Glucocorticoids; Humans; Prednisone; Pulmonary Disease

2022
When to consider Pneumocystis jirovecii prophylaxis in HIV-negative patients.
    JAAPA : official journal of the American Academy of Physician Assistants, 2021, Feb-01, Volume: 34, Issue:2

    Topics: Aged; Anti-Bacterial Agents; Bendamustine Hydrochloride; HIV Seronegativity; Humans; Immunocompromis

2021
Hidden in Plain Sight: An Elusive Cause of Cardiogenic Shock.
    Circulation, 2021, 03-02, Volume: 143, Issue:9

    Topics: Electrocardiography; Humans; Male; Middle Aged; Natriuretic Peptide, Brain; Prednisone; Pulmonary Di

2021
A 69-Year-Old Woman With Ulcerative Colitis and Pulmonary Nodules.
    Chest, 2021, Volume: 159, Issue:3

    Topics: Aged; Anti-Inflammatory Agents; Biopsy; Colitis, Ulcerative; Cryptogenic Organizing Pneumonia; Diagn

2021
Is it safe to start steroids at home for a COPD exacerbation after virtual assessment in the COVID-19 era?
    Cleveland Clinic journal of medicine, 2021, 04-01, Volume: 88, Issue:4

    Topics: COVID-19; Duration of Therapy; Humans; Male; Middle Aged; Prednisone; Pulmonary Disease, Chronic Obs

2021
Relationship of Steroid Dosing and Duration of Mechanical Ventilation in Adult Patients With Acute Exacerbations of Chronic Obstructive Pulmonary Disease.
    Journal of pharmacy practice, 2018, Volume: 31, Issue:2

    Topics: Acute Disease; Aged; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Glucoco

2018
The use of a standardized order set reduces systemic corticosteroid dose and length of stay for individuals hospitalized with acute exacerbations of COPD: a cohort study.
    International journal of chronic obstructive pulmonary disease, 2018, Volume: 13

    Topics: Aged; Disease Progression; Electronic Health Records; Female; Glucocorticoids; Hospitalization; Huma

2018
Systemic Corticosteroid and Antibiotic Use in Hospitalized Patients With Chronic Obstructive Pulmonary Disease Exacerbation.
    The Annals of pharmacotherapy, 2019, Volume: 53, Issue:2

    Topics: Aged; Anti-Bacterial Agents; Cohort Studies; Disease Progression; Female; Glucocorticoids; Hospitali

2019
Disseminated nocardiosis with cerebral and subcutaneous lesions on low-dose prednisone.
    Practical neurology, 2019, Volume: 19, Issue:1

    Topics: Aged; Anti-Inflammatory Agents; Brain; Humans; Immunocompromised Host; Male; Nocardia Infections; Op

2019
Chylothorax due to Venous Thrombosis in a Double-Lung Transplant Patient.
    Archivos de bronconeumologia, 2019, Volume: 55, Issue:7

    Topics: Acute Kidney Injury; Chylothorax; Combined Modality Therapy; Cytomegalovirus Infections; Diet, Fat-R

2019
Immune Checkpoint Inhibitor Outcomes for Patients With Non-Small-Cell Lung Cancer Receiving Baseline Corticosteroids for Palliative Versus Nonpalliative Indications.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2019, 08-01, Volume: 37, Issue:22

    Topics: Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; B7-H1 Antigen; Carcinoma, Non-Small-Cell Lu

2019
Obstructive inflammatory tracheal pseudomembrane.
    Archivos de bronconeumologia, 2013, Volume: 49, Issue:9

    Topics: Aged; Airway Obstruction; Anti-Inflammatory Agents; Bronchi; Combined Modality Therapy; Cough; Exuda

2013
Detection of COPD Exacerbations and compliance with patient-reported daily symptom diaries using a smart phone-based information system [corrected].
    Chest, 2013, Volume: 144, Issue:2

    Topics: Adult; Aged; Anti-Bacterial Agents; Cell Phone; Disease Progression; Female; Glucocorticoids; Humans

2013
Steroids for treatment of COPD exacerbations: less is clearly more.
    JAMA, 2013, Jun-05, Volume: 309, Issue:21

    Topics: Female; Glucocorticoids; Humans; Male; Prednisone; Pulmonary Disease, Chronic Obstructive

2013
[Achilles heel of COPD].
    Praxis, 2013, Jul-03, Volume: 102, Issue:14

    Topics: Achilles Tendon; Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents; Aza Compounds; Diagnosis, Di

2013
[Not Available].
    Medizinische Monatsschrift fur Pharmazeuten, 2013, Volume: 36, Issue:8

    Topics: Female; Glucocorticoids; Humans; Male; Prednisone; Pulmonary Disease, Chronic Obstructive

2013
5 days of prednisone was noninferior to 14 days in patients with acute COPD exacerbation.
    Annals of internal medicine, 2013, Sep-17, Volume: 159, Issue:6

    Topics: Female; Glucocorticoids; Humans; Male; Prednisone; Pulmonary Disease, Chronic Obstructive

2013
A 5-day course of systemic corticosteroids is adequate to treat acute exacerbations of chronic obstructive pulmonary disease.
    Evidence-based medicine, 2014, Volume: 19, Issue:2

    Topics: Female; Glucocorticoids; Humans; Male; Prednisone; Pulmonary Disease, Chronic Obstructive

2014
[Allergic bronchopulmonary aspergillosis in patients with chronic obstructive pulmonary disease: report of 3 cases].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 2013, Volume: 36, Issue:10

    Topics: Aged; Aged, 80 and over; Antibodies, Fungal; Aspergillosis, Allergic Bronchopulmonary; Humans; Immun

2013
Steroids for acute COPD--but for how long?
    The Journal of family practice, 2014, Volume: 63, Issue:1

    Topics: Female; Glucocorticoids; Humans; Male; Prednisone; Pulmonary Disease, Chronic Obstructive

2014
A clinical prediction tool for prognosis in patients with cystic fibrosis, short-term glucocorticoid therapy for chronic obstructive pulmonary disease, and laryngeal ultrasound for prediction of postextubation laryngeal edema.
    American journal of respiratory and critical care medicine, 2014, Feb-15, Volume: 189, Issue:4

    Topics: Cystic Fibrosis; Decision Support Techniques; Female; Glucocorticoids; Humans; Lung; Male; Prednison

2014
Systemic steroids in severe forms of COPD exacerbations: a question of balance?
    The European respiratory journal, 2014, Volume: 43, Issue:3

    Topics: Anti-Inflammatory Agents; Female; Humans; Male; Prednisone; Pulmonary Disease, Chronic Obstructive

2014
Improving adherence for management of acute exacerbation of chronic obstructive pulmonary disease.
    The American journal of medicine, 2014, Volume: 127, Issue:11

    Topics: Continuity of Patient Care; Drug Utilization; Electronic Health Records; Female; Glucocorticoids; Gu

2014
INTERACTIVE MEDICAL CASE. A Woman with Dyspnea and Altered Mental Status.
    The New England journal of medicine, 2016, Jun-09, Volume: 374, Issue:23

    Topics: Acyclovir; Diagnosis, Differential; Dyspnea; Electrocardiography; Encephalitis, Varicella Zoster; Fe

2016
Antibiotics in acute exacerbations of chronic obstructive pulmonary disease.
    Canadian family physician Medecin de famille canadien, 2009, Volume: 55, Issue:1

    Topics: Acute Disease; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Bronchitis, Chr

2009
Central airways obstruction due to Aspergillus fumigatus after lung transplantation.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2009, Volume: 28, Issue:5

    Topics: Airway Obstruction; Antifungal Agents; Aspergillus fumigatus; Bronchoscopy; Diagnosis, Differential;

2009
Screening, prevention and treatment of osteoporosis in patients with chronic obstructive pulmonary disease - a population-based database study.
    The clinical respiratory journal, 2010, Volume: 4, Issue:1

    Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Female; Glucocorticoids; Humans; Male; Mass Screeni

2010
Impact of cytomegalovirus infection in lung transplant patients under universal prophylaxis: single-center experience in Brazil.
    Transplantation proceedings, 2010, Volume: 42, Issue:2

    Topics: Adult; Antibodies, Monoclonal; Azathioprine; Basiliximab; Brazil; Bronchiectasis; Cohort Studies; Cy

2010
Advanced chronic obstructive pulmonary disease is associated with high levels of high-density lipoprotein cholesterol.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2011, Volume: 30, Issue:6

    Topics: Case-Control Studies; Cholesterol, HDL; Cholesterol, LDL; Coronary Artery Disease; Female; Glucocort

2011
Syndrome of inappropriate antidiuretic hormone associated with moxifloxacin.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2012, Feb-01, Volume: 69, Issue:3

    Topics: Aged; Anti-Infective Agents; Aza Compounds; Female; Fluoroquinolones; Follow-Up Studies; Humans; Hyp

2012
Demographic, physiologic and radiographic characteristics of COPD patients taking chronic systemic corticosteroids.
    COPD, 2012, Volume: 9, Issue:1

    Topics: Administration, Oral; Adrenergic beta-Agonists; Asthma; Bronchodilator Agents; Female; Forced Expira

2012
Summaries for patients. A comprehensive care management program to prevent chronic obstructive pulmonary disease hospitalizations.
    Annals of internal medicine, 2012, May-15, Volume: 156, Issue:10

    Topics: Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents; Case Management; Cause of Death; Female; Foll

2012
Biochemistry: A radical treatment.
    Nature, 2012, Sep-27, Volume: 489, Issue:7417

    Topics: Animals; Antioxidants; Clinical Trials as Topic; Disease Models, Animal; Free Radicals; Humans; Isot

2012
Systemic corticosteroids for acute exacerbations of chronic obstructive pulmonary disease.
    The New England journal of medicine, 2003, Jun-26, Volume: 348, Issue:26

    Topics: Acute Disease; Administration, Oral; Glucocorticoids; Humans; Prednisone; Pulmonary Disease, Chronic

2003
Disseminated mucocutaneous leishmaniasis resulting from chronic use of corticosteroid.
    International journal of dermatology, 2003, Volume: 42, Issue:9

    Topics: Aged; Animals; Antiprotozoal Agents; Diagnosis, Differential; Facial Dermatoses; Humans; Immunocompr

2003
Prednisone for chronic obstructive pulmonary disease.
    The New England journal of medicine, 2003, Sep-25, Volume: 349, Issue:13

    Topics: Administration, Oral; Data Interpretation, Statistical; Glucocorticoids; Humans; Prednisone; Pulmona

2003
Prednisone for chronic obstructive pulmonary disease.
    The New England journal of medicine, 2003, Sep-25, Volume: 349, Issue:13

    Topics: Dyspnea; Glucocorticoids; Humans; Prednisone; Pulmonary Disease, Chronic Obstructive; Secondary Prev

2003
Prednisone for chronic obstructive pulmonary disease.
    The New England journal of medicine, 2003, Sep-25, Volume: 349, Issue:13

    Topics: Bronchodilator Agents; Forced Expiratory Volume; Glucocorticoids; Humans; Prednisone; Pulmonary Dise

2003
Prednisone for chronic obstructive pulmonary disease.
    The New England journal of medicine, 2003, Sep-25, Volume: 349, Issue:13

    Topics: Administration, Oral; Adrenal Gland Diseases; Aged; Bone Density; Glucocorticoids; Humans; Prednison

2003
Oral prednisone prevents relapse in COPD exacerbations.
    The Journal of family practice, 2003, Volume: 52, Issue:10

    Topics: Administration, Oral; Aged; Ambulatory Care; Anti-Inflammatory Agents; Double-Blind Method; Dyspnea;

2003
Decreased levels of myeloperoxidase in induced sputum of patients with COPD after treatment with oral glucocorticoids.
    Chest, 2004, Volume: 126, Issue:2

    Topics: Administration, Oral; Enzyme-Linked Immunosorbent Assay; Female; Glucocorticoids; Humans; Interleuki

2004
Fatal visceral leishmaniasis, with massive bone-marrow infection, in an immunosuppressed but HIV-negative Spanish patient, after the initiation of treatment with meglumine antimoniate.
    Annals of tropical medicine and parasitology, 2005, Volume: 99, Issue:2

    Topics: Antiprotozoal Agents; Bone Marrow; Bone Marrow Diseases; Fatal Outcome; Glucocorticoids; HIV Seroneg

2005
Practice patterns in patients at risk for glucocorticoid-induced osteoporosis.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2005, Volume: 16, Issue:12

    Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Asthma; Bone De

2005
[Clinical observation of bushen naqi huoxue granules in treating patients with chronic obstructive lung disease].
    Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, 2005, Volume: 3, Issue:6

    Topics: Adult; Aged; Aminophylline; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Forced Expirat

2005
[Pneumonia by Corynebacterium pseudodiphteriticum: an infection to consider].
    Anales de medicina interna (Madrid, Spain : 1984), 2006, Volume: 23, Issue:3

    Topics: Aged; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Ceftriaxone; Corynebacte

2006
[Sarcoidosis and granulomatous disease: observation].
    Revue des maladies respiratoires, 2006, Volume: 23, Issue:2 Pt 2

    Topics: Anti-Inflammatory Agents; Glucocorticoids; Humans; Immunosuppressive Agents; Male; Methotrexate; Mid

2006
[Spontaneous bilateral rupture of the Achilles tendon in an elderly woman undergoing prednisone pulse therapy with a history of polymyalgia rheumatica].
    Nederlands tijdschrift voor geneeskunde, 2006, Sep-30, Volume: 150, Issue:39

    Topics: Achilles Tendon; Aged, 80 and over; Female; Glucocorticoids; Humans; Polymyalgia Rheumatica; Prednis

2006
[Cost analysis for inpatient therapy for patients with acute exacerbations of chronic obstructive pulmonary disease].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2006, Volume: 44, Issue:11

    Topics: Activities of Daily Living; Adult; Aged; Costs and Cost Analysis; Female; Health Care Costs; Hospita

2006
Rhinocerebral mucormycosis acquired after a short course of prednisone therapy.
    The Journal of the American Osteopathic Association, 2007, Volume: 107, Issue:11

    Topics: Aged; Amphotericin B; Antifungal Agents; Brain Diseases; Comorbidity; Diabetes Mellitus; Disease Pro

2007
A rare case of lung coinfection by Streptomyces cinereoruber and Haemophilus influenzae in a patient with severe chronic obstructive pulmonary disease: characterization at species level using molecular techniques.
    Diagnostic microbiology and infectious disease, 2008, Volume: 60, Issue:3

    Topics: Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents; Bacterial Typing Techniques; DNA, Bacterial;

2008
Effect of a 14-day course of systemic corticosteroids on the hypothalamic-pituitary-adrenal-axis in patients with acute exacerbation of chronic obstructive pulmonary disease.
    BMC pulmonary medicine, 2008, Jan-26, Volume: 8

    Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; Aged; Aged, 80 and over; Diagnostic Techniques,

2008
Spontaneous bilateral rupture of the Achilles tendon in a patient with chronic obstructive pulmonary disease.
    Respirology (Carlton, Vic.), 2002, Volume: 7, Issue:2

    Topics: Achilles Tendon; Aged; Glucocorticoids; Humans; Male; Prednisone; Pulmonary Disease, Chronic Obstruc

2002