prednisone has been researched along with Acute-Phase Reaction in 5 studies
Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.
Acute-Phase Reaction: An early local inflammatory reaction to insult or injury that consists of fever, an increase in inflammatory humoral factors, and an increased synthesis by hepatocytes of a number of proteins or glycoproteins usually found in the plasma.
| Excerpt | Relevance | Reference |
|---|---|---|
| "98 (1 kg(-1) x h(-1)) and the elimination half-life was 1." | 2.69 | Pharmacokinetics of intravenous methylprednisolone and oral prednisone in paediatric patients with inflammatory bowel disease during the acute phase and in remission. ( André, J; Cèzard, JP; Faure, C; Giraud, M; Jacqz-Aigrain, E; Munck, A; Pelatan, C, 1998) |
| "Prednisone pretreatment did not alter the immediate skin erythema or release of histamine but ablated the late secondary erythema and rise in histamine." | 2.67 | Prednisone inhibits the appearance of inflammatory mediators and the influx of eosinophils and basophils associated with the cutaneous late-phase response to allergen. ( Charlesworth, EN; Kagey-Sobotka, A; Lichtenstein, LM; Norman, PS; Schleimer, RP, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hernández-Rodríguez, J | 1 |
| Segarra, M | 1 |
| Vilardell, C | 1 |
| Sánchez, M | 1 |
| García-Martínez, A | 1 |
| Esteban, MJ | 1 |
| Queralt, C | 1 |
| Grau, JM | 1 |
| Urbano-Márquez, A | 1 |
| Palacín, A | 1 |
| Colomer, D | 1 |
| Cid, MC | 1 |
| Bertoli, AM | 1 |
| Font, YM | 1 |
| Nadal, A | 1 |
| Vilá, LM | 1 |
| Pascali, E | 1 |
| Faure, C | 1 |
| André, J | 1 |
| Pelatan, C | 1 |
| Munck, A | 1 |
| Giraud, M | 1 |
| Cèzard, JP | 1 |
| Jacqz-Aigrain, E | 1 |
| Charlesworth, EN | 1 |
| Kagey-Sobotka, A | 1 |
| Schleimer, RP | 1 |
| Norman, PS | 1 |
| Lichtenstein, LM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Study of Pharmacokinetic Variability of Glucocorticoids in Children[NCT02252237] | 146 participants (Actual) | Observational | 2014-12-03 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for prednisone and Acute-Phase Reaction
| Article | Year |
|---|---|
Diagnosis and treatment of primary amyloidosis.
Topics: Acute-Phase Reaction; Adult; Aged; Amyloid; Amyloidosis; B-Lymphocytes; Biopsy; Child; Contraindicat | 1995 |
2 trials available for prednisone and Acute-Phase Reaction
| Article | Year |
|---|---|
Pharmacokinetics of intravenous methylprednisolone and oral prednisone in paediatric patients with inflammatory bowel disease during the acute phase and in remission.
Topics: Acute-Phase Reaction; Administration, Oral; Adolescent; Anti-Inflammatory Agents; Child; Child, Pres | 1998 |
Prednisone inhibits the appearance of inflammatory mediators and the influx of eosinophils and basophils associated with the cutaneous late-phase response to allergen.
Topics: Acute-Phase Reaction; Adult; Allergens; Basophils; Blister; Dermatitis; Eosinophils; Female; Histami | 1991 |
2 other studies available for prednisone and Acute-Phase Reaction
| Article | Year |
|---|---|
Tissue production of pro-inflammatory cytokines (IL-1beta, TNFalpha and IL-6) correlates with the intensity of the systemic inflammatory response and with corticosteroid requirements in giant-cell arteritis.
Topics: Acute-Phase Reaction; Aged; Aged, 80 and over; Chi-Square Distribution; Cytokines; Female; Giant Cel | 2004 |
Differences between active treatment and placebo groups in the study of induction treatment of giant cell arteritis with high-dose glucocorticoids: comment on the article by Mazlumzadeh et al.
Topics: Acute-Phase Reaction; Anti-Inflammatory Agents; Blood Sedimentation; C-Reactive Protein; Dose-Respon | 2007 |