prednisone has been researched along with Abnormalities, Congenital in 15 studies
Prednisone: A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
prednisone : A synthetic glucocorticoid drug that is particularly effective as an immunosuppressant, and affects virtually all of the immune system. Prednisone is a prodrug that is converted by the liver into prednisolone (a beta-hydroxy group instead of the oxo group at position 11), which is the active drug and also a steroid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twelve women (12%) experienced 13 miscarriages after a median of 50 months (range, 13-120) from the end of therapy." | 1.38 | Impact of different treatment approaches on pregnancy outcomes in 99 women treated for Hodgkin lymphoma. ( Alfò, M; Annechini, G; Cavalieri, E; De Sanctis, V; Enrici, RM; Filippone, FR; Minniti, G; Muni, R; Osti, MF; Pulsoni, A; Valeriani, M, 2012) |
| "In 40 to 50% of DBA patients, congenital abnormalities mostly in the cephalic area and in thumbs and upper limbs have been described." | 1.36 | Diamond-Blackfan anemia, ribosome and erythropoiesis. ( Da Costa, L; Leblanc, T; Mohandas, N; Moniz, H; Simansour, M; Tchernia, G, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (60.00) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 3 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Da Costa, L | 1 |
| Moniz, H | 1 |
| Simansour, M | 1 |
| Tchernia, G | 1 |
| Mohandas, N | 1 |
| Leblanc, T | 1 |
| De Sanctis, V | 1 |
| Filippone, FR | 1 |
| Alfò, M | 1 |
| Muni, R | 1 |
| Cavalieri, E | 1 |
| Pulsoni, A | 1 |
| Annechini, G | 1 |
| Valeriani, M | 1 |
| Osti, MF | 1 |
| Minniti, G | 1 |
| Enrici, RM | 1 |
| Langen, ES | 1 |
| Chakravarty, EF | 1 |
| Liaquat, M | 1 |
| El-Sayed, YY | 1 |
| Druzin, ML | 1 |
| ZUNIN, C | 1 |
| BORRONE, C | 1 |
| CUNEO, P | 1 |
| KHETARPAL, SK | 1 |
| SUBRAHMANYAM, VV | 1 |
| BODIAN, M | 1 |
| SHELDON, W | 1 |
| LIGHTWOOD, R | 1 |
| RUHRMANN, G | 1 |
| Bonaminio, PN | 1 |
| de Regnier, R | 1 |
| Chang, E | 1 |
| Day, N | 1 |
| Manzi, S | 1 |
| Ramsey-Goldman, R | 1 |
| Dein, RA | 1 |
| Mennuti, MT | 1 |
| Kovach, P | 1 |
| Gabbe, SG | 1 |
| Martínez-Rueda, JO | 1 |
| Arce-Salinas, CA | 1 |
| Kraus, A | 1 |
| Alcocer-Varela, J | 1 |
| Alarcón-Segovia, D | 1 |
| Powell, J | 1 |
| Holtorff, J | 2 |
| Haller, H | 2 |
| Strauzenberg, E | 1 |
| Wallace, MR | 1 |
| Smedley, MG | 1 |
| Strauzenberg, SE | 1 |
| Gordon, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase I/II, Open-Label Study to Determine Safety and Efficacy of Sotatercept (ACE-011) in Adults With Red Blood Cell Transfusion- Dependent Diamond Blackfan Anemia[NCT01464164] | Phase 1/Phase 2 | 19 participants (Actual) | Interventional | 2012-01-31 | Terminated (stopped due to Supporter terminated the study due to no active patients (secondary to travel restrictions due to COVID).) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Complete response is transfusion independence with hemoglobin >9 gm/dl; partial response is transfusion dependence with hemoglobin < 9gm/dl with an increase in reticulocyte count over baseline (NCT01464164)
Timeframe: 9 months
| Intervention | Participants (Count of Participants) |
|---|---|
| Sotatercept Cohort 1 | 0 |
| Sotatercept Cohort 2 | 0 |
| Sotatercept Cohort 3 | 0 |
| Sotatercept With Prednisone Boost Cohort 4a | 0 |
| Sotatercept Cohort 4b | 0 |
| Sotatercept With Prednisone Boost Cohort 5a | 0 |
| Sotatercept Cohort 5b | 0 |
Assess severity of adverse events and relationship to sotatercept according to the currently active minor version of the NCI Common Terminology for Adverse Events version 4.0 (NCT01464164)
Timeframe: 9 months
| Intervention | Participants (Count of Participants) |
|---|---|
| Sotatercept Cohort 1 | 0 |
| Sotatercept Cohort 2 | 0 |
| Sotatercept Cohort 3 | 0 |
| Sotatercept With Prednisone Boost Cohort 4a | 0 |
| Sotatercept Cohort 4b | 0 |
| Sotatercept With Prednisone Boost Cohort 5a | 0 |
| Sotatercept Cohort 5b | 0 |
2 reviews available for prednisone and Abnormalities, Congenital
| Article | Year |
|---|---|
The reproductive potential of young men and women with Hodgkin's disease.
Topics: Adult; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Congenital Abnormalities; Female; | 1984 |
Update on hemangiomas and vascular malformations.
Topics: Child; Congenital Abnormalities; Female; Glucocorticoids; Hemangioma; Humans; Laser Therapy; Male; N | 1999 |
13 other studies available for prednisone and Abnormalities, Congenital
| Article | Year |
|---|---|
Diamond-Blackfan anemia, ribosome and erythropoiesis.
Topics: Anemia; Anemia, Diamond-Blackfan; Anemia, Macrocytic; Blood Transfusion; Bone Marrow; Chromosomes, H | 2010 |
Impact of different treatment approaches on pregnancy outcomes in 99 women treated for Hodgkin lymphoma.
Topics: Abortion, Spontaneous; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Congenital | 2012 |
High rate of preterm birth in pregnancies complicated by rheumatoid arthritis.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Congenital Abnormalities; Female; Fetal Distress | 2014 |
[Prednisone and pregnancy. Experimental research and clinical observations on the teratogenic effect of prednisone].
Topics: Congenital Abnormalities; Female; Humans; Prednisone; Pregnancy | 1960 |
SCLEREMA NEONATORUM: A STUDY OF 17 CASES.
Topics: Anti-Bacterial Agents; Congenital Abnormalities; Cortisone; Esophageal Fistula; Humans; Infant; Infa | 1964 |
CONGENITAL HYPOPLASIA OF THE EXOCRINE PANCREAS.
Topics: Agranulocytosis; Anemia; Biopsy; Child; Congenital Abnormalities; Cystic Fibrosis; Genetics, Medical | 1964 |
[GUIDING SYMPTOM: STRIDOR DURING THE 1ST LIFE YEAR].
Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Congenital Abnormalities; Diagnosis, Differentia | 1964 |
Minor physical anomalies are not increased in the offspring of mothers with systemic lupus erythematosus.
Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Congenital Abnormalities; Fe | 2006 |
Factors associated with fetal losses in severe systemic lupus erythematosus.
Topics: Adult; Analysis of Variance; Azathioprine; Case-Control Studies; Chloroquine; Cohort Studies; Congen | 1996 |
[Significance of abnormal fetal developments for the detection of prediabetic state].
Topics: Birth Weight; Congenital Abnormalities; Diabetes Mellitus; Embryonic and Fetal Development; Female; | 1972 |
The transient nephrotic syndrome of pregnancy.
Topics: Adult; Albuminuria; Cholesterol; Congenital Abnormalities; Diuretics; Edema; Female; Fetal Death; Hu | 1970 |
[The significance of prediabetes of the mother for the fate of the child].
Topics: Adult; Birth Weight; Congenital Abnormalities; Female; Fetal Death; Glucose Tolerance Test; Humans; | 1967 |
Genetical, social, and medical aspects of abortion.
Topics: Abnormalities, Drug-Induced; Abortion, Criminal; Abortion, Legal; Abortion, Therapeutic; Adolescent; | 1968 |