prednisolone-hemisuccinate has been researched along with Calcinosis* in 2 studies
2 other study(ies) available for prednisolone-hemisuccinate and Calcinosis
Article | Year |
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[Experimental peritoneal calcinosis--glucocorticoid as inhibitor].
Peritoneal disturbances in the course of continuous ambulatory peritoneal dialysis (CAPD) are therapeutical relevant. Even calcifications are described in rarely cases. Concerning these cases an experimental model is known being created by Selye and belonging to the calciphylactic concept. In 8 female Wistar rats (weighing 140 to 180 g) this experiment was reproduced and in a similar series an inhibition was achieved by intraperitoneal application of a glucocorticoid. Experiments in this kind give a pathogenetic contribution for peritoneal disturbances and also possible therapeutic hints. Topics: Animals; Calcinosis; Disease Models, Animal; Female; Injections, Intraperitoneal; Peritoneal Dialysis, Continuous Ambulatory; Peritoneal Diseases; Peritoneum; Prednisolone; Rats; Rats, Inbred Strains | 1991 |
[Prednisolone as a calcification inhibitor--a calciphylactic experiment in the rat pancreas].
In the experimental situation the inhibitory potency of prednisolone on soft tissue calcification is confirmed. This glucocorticoid was locally applied prior to the commencement of a mastocalciphylactic experiment (Selye). Dosage: 10 mg per animal, body mass 150-180 g. In 16 out of 17 female rats there were no calcified deposits in the interstitium of the pancreas but in nearly all of the control animals a typical calciphylactic reaction could be found. It is suggested that glucocorticoids act by alteration of pancreatic mast cells. Topics: Animals; Calcinosis; Female; Pancreas; Pancreatic Diseases; Prednisolone; Rats; Rats, Inbred Strains | 1983 |