prednisolone-farnesylate and Dermatitis--Contact

prednisolone-farnesylate has been researched along with Dermatitis--Contact* in 1 studies

Other Studies

1 other study(ies) available for prednisolone-farnesylate and Dermatitis--Contact

ArticleYear
[Effects of prednisolone farnesylate (PNF) gel on skin and ocular mucosa].
    The Journal of toxicological sciences, 1992, Volume: 17 Suppl 3

    Various tests for irritation, phototoxicity, contact sensitivity and photocontact sensitivity of PNF gel were conducted. The results were as follows. 1) In the primary dermal irritation test and trypan blue test, slight erythema was noted in the rabbits treated with 0.8 and 1.6% PNF gel, although similar reaction occurred in those treated with the base. 2) In the test for the primary irritation to the ocular mucosa, severe irritant reactions were caused by 0.8 and 1.6% PNF gel and its base. However these reactions disappeared 7 days after irritation. 3) In the phototoxicity test and contact sensitivity test, no positive reactions were detected by 0.8 and 1.6% PNF gel. On the other hand, in the photocontact sensitivity test, positive reaction were noted in the guinea pig treated with 0.8 and 1.6% PNF gel and its base.

    Topics: Animals; Dermatitis, Contact; Dermatitis, Phototoxic; Eye; Farnesol; Female; Gels; Guinea Pigs; Male; Mucous Membrane; Prednisolone; Rabbits; Skin

1992