prednisolone has been researched along with Tuberous Sclerosis in 5 studies
Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.
Tuberous Sclerosis: Autosomal dominant neurocutaneous syndrome classically characterized by MENTAL RETARDATION; EPILEPSY; and skin lesions (e.g., adenoma sebaceum and hypomelanotic macules). There is, however, considerable heterogeneity in the neurologic manifestations. It is also associated with cortical tuber and HAMARTOMAS formation throughout the body, especially the heart, kidneys, and eyes. Mutations in two loci TSC1 and TSC2 that encode hamartin and tuberin, respectively, are associated with the disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The protocol required that infants be treated with high-dose oral prednisolone except those with tuberous sclerosis complex (TSC) who were treated with vigabatrin." | 3.78 | Epileptic spasms: experience with a high-dose oral corticosteroid protocol. ( Freeman, JL; Harvey, AS; Mackay, MT; Ware, TL, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grinspan, ZM | 1 |
| Mytinger, JR | 1 |
| Baumer, FM | 1 |
| Ciliberto, MA | 1 |
| Cohen, BH | 1 |
| Dlugos, DJ | 1 |
| Harini, C | 1 |
| Hussain, SA | 1 |
| Joshi, SM | 1 |
| Keator, CG | 1 |
| Knupp, KG | 1 |
| McGoldrick, PE | 1 |
| Nickels, KC | 1 |
| Park, JT | 1 |
| Pasupuleti, A | 1 |
| Patel, AD | 1 |
| Pomeroy, SL | 1 |
| Shahid, AM | 1 |
| Shellhaas, RA | 1 |
| Shrey, DW | 1 |
| Singh, RK | 1 |
| Wolf, SM | 1 |
| Yozawitz, EG | 1 |
| Yuskaitis, CJ | 1 |
| Waugh, JL | 1 |
| Pearl, PL | 1 |
| Marinelli, T | 1 |
| Chen, L | 1 |
| Kulkarni, J | 1 |
| Ware, TL | 1 |
| Mackay, MT | 1 |
| Harvey, AS | 1 |
| Freeman, JL | 1 |
| KOLAR, O | 1 |
| KHOKHLOVA, ZE | 1 |
| KRUPINA, TN | 1 |
| IAKUNIN, IuA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prednisolone vs. Vigabatrin in the First-line Treatment of Infantile Spasms[NCT02299115] | Phase 3 | 0 participants (Actual) | Interventional | 2017-09-05 | Withdrawn (stopped due to Most centres are now using oral steroids as 1st line treatment so question of efficacy is no longer of high interest.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 other studies available for prednisolone and Tuberous Sclerosis
| Article | Year |
|---|---|
Crisis Standard of Care: Management of Infantile Spasms during COVID-19.
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Betacoronavirus; Coronavirus Infections; COVID-19; Del | 2020 |
First episode psychosis in an adult patient with tuberous sclerosis.
Topics: Benzodiazepines; Female; Humans; Middle Aged; Olanzapine; Prednisolone; Psychotic Disorders; Tuberou | 2016 |
Epileptic spasms: experience with a high-dose oral corticosteroid protocol.
Topics: Clinical Protocols; Dose-Response Relationship, Drug; Epilepsy; Female; Glucocorticoids; Guideline A | 2012 |
[Intrathecal application of ultracortenol in subacute panencephalitis].
Topics: Communicable Diseases; Diffuse Cerebral Sclerosis of Schilder; Humans; Levobunolol; Nervous System D | 1962 |
[SUBACUTE SUDANOPHILIC LEUKODYSTROPHY OF THE PELIZAEUS-MERZBACHER TYPE].
Topics: Adrenocorticotropic Hormone; Child; Diffuse Cerebral Sclerosis of Schilder; Humans; Pelizaeus-Merzba | 1965 |