Page last updated: 2024-11-06

prednisolone and Thyrotoxicosis

prednisolone has been researched along with Thyrotoxicosis in 23 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Thyrotoxicosis: A hypermetabolic syndrome caused by excess THYROID HORMONES which may come from endogenous or exogenous sources. The endogenous source of hormone may be thyroid HYPERPLASIA; THYROID NEOPLASMS; or hormone-producing extrathyroidal tissue. Thyrotoxicosis is characterized by NERVOUSNESS; TACHYCARDIA; FATIGUE; WEIGHT LOSS; heat intolerance; and excessive SWEATING.

Research Excerpts

ExcerptRelevanceReference
"Amiodarone-induced thyrotoxicosis (AIT) is a complex therapeutic challenge."9.10A stepwise approach to the treatment of amiodarone-induced thyrotoxicosis. ( Başkal, N; Erdogan, G; Erdogan, MF; Güleç, S; Tutar, E, 2003)
" He was diagnosed with atrial fibrillation 2 years previously and started on amiodarone and warfarin."7.80Amiodarone-induced thyrotoxicosis: type 1 or type 2? ( Khan, A; Puttanna, A; Raskauskiene, D, 2014)
"Amiodarone-induced thyrotoxicosis (AIT) with features consistent with both AIT type I (in which thyroid antibodies and nodular goiter are present) and AIT type II (which is not responsive to thionamide therapy and eventually leads to permanent hypothyroidism)."7.74Treatment of amiodarone-associated thyrotoxicosis. ( Franklyn, JA; Gammage, MD, 2007)
"Amiodarone-induced thyrotoxicosis (AIT) type 1 occurs in subjects with an underlying thyroid disease, whereas type 2 AIT is a form of destructive thyroiditis."7.73Amiodarone-induced thyrotoxicosis due to destructive thyroiditis: therapeutic recommendations. ( Dietlein, M; Schicha, H, 2005)
"Current thinking is that amiodarone-induced thyrotoxicosis (AIT) might be either iodine-induced thyrotoxicosis in latent hyperthyroidism (Type 1) or destructive thyroiditis (Type 2), and also that colour-flow Doppler sonography (CFDS) of the thyroid and serum interleukin 6 (IL-6) are tools that can classify AIT and direct treatment."7.71Clinical experience of amiodarone-induced thyrotoxicosis over a 3-year period: role of colour-flow Doppler sonography. ( Bennet, WM; Eaton, SE; Euinton, HA; Newman, CM; Weetman, AP, 2002)
"We report two patients whose thyrotoxicosis failed to respond to conventional treatment with carbimazole."7.69Treatment of thyrotoxicosis resistant to carbimazole with corticosteroids. ( Dale, J; Dodson, PM; Jude, EB; Kumar, S, 1996)
"We describe a patient who was treated with amiodarone for ventricular arrhythmia based on arrhythmogenic right ventricular dysplasia and who subsequently developed severe amiodarone-induced thyrotoxicosis."7.69A case of amiodarone-induced thyrotoxicosis successfully treated with prednisolone. ( Hayashi, K; Kondoh, J; Numaguchi, Y; Sassa, H; Sone, T; Suzuki, T; Tsuboi, H, 1997)
"Amiodarone is a widely used anti-arrhythmic drug."5.40An audit of amiodarone-induced thyrotoxicosis--do anti-thyroid drugs alone provide adequate treatment? ( Inder, WJ; Kaye, G; Patel, N; Sullivan, C, 2014)
"Amiodarone-induced thyrotoxicosis (AIT) is a complex therapeutic challenge."5.10A stepwise approach to the treatment of amiodarone-induced thyrotoxicosis. ( Başkal, N; Erdogan, G; Erdogan, MF; Güleç, S; Tutar, E, 2003)
" He was diagnosed with atrial fibrillation 2 years previously and started on amiodarone and warfarin."3.80Amiodarone-induced thyrotoxicosis: type 1 or type 2? ( Khan, A; Puttanna, A; Raskauskiene, D, 2014)
" He improved rapidly but went on to develop hypothyroidism on follow-up and required levothyroxine replacement."3.75An uncommon endocrine cause of pyrexia of unknown origin. ( Alexander, V; Chattopadhyay, A; Kurien, TT, 2009)
"Amiodarone-induced thyrotoxicosis (AIT) with features consistent with both AIT type I (in which thyroid antibodies and nodular goiter are present) and AIT type II (which is not responsive to thionamide therapy and eventually leads to permanent hypothyroidism)."3.74Treatment of amiodarone-associated thyrotoxicosis. ( Franklyn, JA; Gammage, MD, 2007)
"Amiodarone-induced thyrotoxicosis (AIT) type 1 occurs in subjects with an underlying thyroid disease, whereas type 2 AIT is a form of destructive thyroiditis."3.73Amiodarone-induced thyrotoxicosis due to destructive thyroiditis: therapeutic recommendations. ( Dietlein, M; Schicha, H, 2005)
"Current thinking is that amiodarone-induced thyrotoxicosis (AIT) might be either iodine-induced thyrotoxicosis in latent hyperthyroidism (Type 1) or destructive thyroiditis (Type 2), and also that colour-flow Doppler sonography (CFDS) of the thyroid and serum interleukin 6 (IL-6) are tools that can classify AIT and direct treatment."3.71Clinical experience of amiodarone-induced thyrotoxicosis over a 3-year period: role of colour-flow Doppler sonography. ( Bennet, WM; Eaton, SE; Euinton, HA; Newman, CM; Weetman, AP, 2002)
"We report two patients whose thyrotoxicosis failed to respond to conventional treatment with carbimazole."3.69Treatment of thyrotoxicosis resistant to carbimazole with corticosteroids. ( Dale, J; Dodson, PM; Jude, EB; Kumar, S, 1996)
"We describe a patient who was treated with amiodarone for ventricular arrhythmia based on arrhythmogenic right ventricular dysplasia and who subsequently developed severe amiodarone-induced thyrotoxicosis."3.69A case of amiodarone-induced thyrotoxicosis successfully treated with prednisolone. ( Hayashi, K; Kondoh, J; Numaguchi, Y; Sassa, H; Sone, T; Suzuki, T; Tsuboi, H, 1997)
"Amiodarone is a widely used anti-arrhythmic drug."1.40An audit of amiodarone-induced thyrotoxicosis--do anti-thyroid drugs alone provide adequate treatment? ( Inder, WJ; Kaye, G; Patel, N; Sullivan, C, 2014)
"TINU syndrome with hyperthyroidism is rare."1.36[Adult male with tubulointerstitial nephritis and uveitis syndrome complicated with thyroiditis]. ( Fujii, T; Iwamoto, S; Kakei, S; Matsui, N; Tanaka, H; Toda, T, 2010)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.70)18.7374
1990's9 (39.13)18.2507
2000's7 (30.43)29.6817
2010's5 (21.74)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jolobe, OMP1
Jamieson, A1
Patel, N1
Inder, WJ1
Sullivan, C1
Kaye, G1
Khan, A1
Puttanna, A1
Raskauskiene, D1
Alexander, V1
Kurien, TT1
Chattopadhyay, A1
Iwamoto, S1
Kakei, S1
Tanaka, H1
Fujii, T1
Toda, T1
Matsui, N1
Arvola, T1
Mustalahti, K1
Saha, MT1
Vehmanen, P1
Partanen, J1
Ashorn, M1
Erdogan, MF1
Güleç, S1
Tutar, E1
Başkal, N1
Erdogan, G1
FROLOVA, AI1
Dietlein, M1
Schicha, H1
Sato, K2
Franklyn, JA1
Gammage, MD1
Iaizzo, PA1
Quasthoff, S1
Lehmann-Horn, F1
Jude, EB1
Dale, J1
Kumar, S1
Dodson, PM1
van Dam, GM1
Reisman, Y1
van Wieringen, K1
Hayashi, K1
Sone, T1
Suzuki, T1
Numaguchi, Y1
Kondoh, J1
Tsuboi, H1
Sassa, H1
Rink, T1
Wieg, C1
Schroth, HJ1
Helisch, A1
Bertram, U1
Miyakawa, M1
Eto, M1
Inaba, T1
Matsuda, N1
Shiga, T1
Ohnishi, S1
Kasanuki, H1
Eaton, SE1
Euinton, HA1
Newman, CM1
Weetman, AP1
Bennet, WM1
Mercer, M1
Balazs, C1
Farid, NR1
Shrivastava, MP1
Datta, TK1
Madiajagne, R1
Epishin, AV1
Epishina, NA1
Solomko, LD1
Kuz'min, IuP1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Multi-center, Open Label, Randomised Parallel- Group Study to Compare the Efficacy of Cholestyramine Plus Standard Treatment Versus Prednisolone Plus Standard Treatment Versus Standard Treatment Alone in Treatment of Overt Hyperthyroidism[NCT03303053]Phase 3135 participants (Anticipated)Interventional2017-05-11Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for prednisolone and Thyrotoxicosis

ArticleYear
[Drug (amiodarone)-induced thyroid disease].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 10

    Topics: Amiodarone; Hormone Replacement Therapy; Humans; Hypothyroidism; Perchlorates; Prednisolone; Thyroto

2005
Hypokalaemic thyrotoxic periodic paralysis: case report and review of an Oriental syndrome.
    The Netherlands journal of medicine, 1996, Volume: 49, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Anti-Inflammatory Agents; Antithyroid Agents; Humans; Hypokalemi

1996

Trials

1 trial available for prednisolone and Thyrotoxicosis

ArticleYear
A stepwise approach to the treatment of amiodarone-induced thyrotoxicosis.
    Thyroid : official journal of the American Thyroid Association, 2003, Volume: 13, Issue:2

    Topics: Amiodarone; Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Antibodies; Antithyroid Agents; Female

2003

Other Studies

20 other studies available for prednisolone and Thyrotoxicosis

ArticleYear
Adrenal insufficiency - recognition and management.
    Clinical medicine (London, England), 2017, Volume: 17, Issue:5

    Topics: Addison Disease; Adult; Aged; Antithyroid Agents; Carbimazole; Dose-Response Relationship, Drug; Fem

2017
Drugs, the Thyroid, and the Heart: A Lethal Cocktail.
    The American journal of medicine, 2019, Volume: 132, Issue:3

    Topics: Agranulocytosis; Amiodarone; Anti-Arrhythmia Agents; Antithyroid Agents; Atrial Fibrillation; Carbim

2019
An audit of amiodarone-induced thyrotoxicosis--do anti-thyroid drugs alone provide adequate treatment?
    Heart, lung & circulation, 2014, Volume: 23, Issue:6

    Topics: Amiodarone; Anti-Arrhythmia Agents; Antithyroid Agents; Female; Glucocorticoids; Humans; Medical Aud

2014
Amiodarone-induced thyrotoxicosis: type 1 or type 2?
    BMJ case reports, 2014, Oct-27, Volume: 2014

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Antithyroid Agents; Atrial Fibrillation; Carbimazole; Gluc

2014
An uncommon endocrine cause of pyrexia of unknown origin.
    The Journal of the Association of Physicians of India, 2009, Volume: 57

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Biopsy, Fine-Needle; Drug Therapy, Combination; Feve

2009
[Adult male with tubulointerstitial nephritis and uveitis syndrome complicated with thyroiditis].
    Nihon Jinzo Gakkai shi, 2010, Volume: 52, Issue:4

    Topics: Glucocorticoids; Humans; Hyperthyroidism; Male; Middle Aged; Nephritis, Interstitial; Prednisolone;

2010
Celiac disease, thyrotoxicosis, and autoimmune hepatitis in a child.
    Journal of pediatric gastroenterology and nutrition, 2002, Volume: 35, Issue:1

    Topics: Alanine Transaminase; Autoimmune Diseases; Celiac Disease; Child; Diet; Female; Gliadin; Glutens; Ha

2002
[UROPEPSIN CONTENT IN PATIENTS WITH THYROTOXICOSIS AND OTHER DISEASES BEFORE AND AFTER THERAPY].
    Terapevticheskii arkhiv, 1964, Volume: 36

    Topics: Drug Therapy; Endopeptidases; Gastric Acidity Determination; Humans; Hyperthyroidism; Hypothyroidism

1964
Amiodarone-induced thyrotoxicosis due to destructive thyroiditis: therapeutic recommendations.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2005, Volume: 113, Issue:3

    Topics: Adult; Aged; Amiodarone; Antithyroid Agents; Carbimazole; Drug Therapy, Combination; Female; Glucoco

2005
Treatment of amiodarone-associated thyrotoxicosis.
    Nature clinical practice. Endocrinology & metabolism, 2007, Volume: 3, Issue:9

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Carbimazole; Hormone Replacement Therapy; Humans; Hypothyr

2007
Differential diagnosis of periodic paralysis aided by in vitro myography.
    Neuromuscular disorders : NMD, 1995, Volume: 5, Issue:2

    Topics: Adult; Diagnosis, Differential; Epinephrine; Female; Humans; In Vitro Techniques; Lithium; Male; Mid

1995
Treatment of thyrotoxicosis resistant to carbimazole with corticosteroids.
    Postgraduate medical journal, 1996, Volume: 72, Issue:850

    Topics: Adult; Antithyroid Agents; Carbimazole; Drug Resistance; Drug Therapy, Combination; Female; Humans;

1996
A case of amiodarone-induced thyrotoxicosis successfully treated with prednisolone.
    Japanese circulation journal, 1997, Volume: 61, Issue:4

    Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Humans; Male; Prednisolone; Tac

1997
[Hyperthyroidism in a premature infant due to transplacental passage of maternal thyrotropin receptor antibodies].
    Nuklearmedizin. Nuclear medicine, 1999, Volume: 38, Issue:5

    Topics: Adult; Anti-Arrhythmia Agents; Antithyroid Agents; Autoantibodies; Carbimazole; Cardiotonic Agents;

1999
Clinical characteristics of amiodarone-induced thyrotoxicosis and hypothyroidism in Japan.
    Endocrine journal, 1999, Volume: 46, Issue:3

    Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Antithyroid Agents; Female; Humans; Hypothyroidism;

1999
Clinical experience of amiodarone-induced thyrotoxicosis over a 3-year period: role of colour-flow Doppler sonography.
    Clinical endocrinology, 2002, Volume: 56, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Antith

2002
Amiodarone-induced thyrotoxicosis responding to oral steroid therapy.
    Postgraduate medical journal, 1992, Volume: 68, Issue:799

    Topics: Administration, Oral; Amiodarone; Humans; Male; Middle Aged; Prednisolone; Thyrotoxicosis

1992
Soluble interleukin-2 receptor in sera of patients with Graves' disease.
    Journal of autoimmunity, 1991, Volume: 4, Issue:4

    Topics: Autoantibodies; Eye Diseases; Female; Graves Disease; Humans; Male; Methimazole; Prednisolone; Recep

1991
Thyrotoxicosis with myasthenia--an unusual association.
    Journal of the Indian Medical Association, 1991, Volume: 89, Issue:9

    Topics: Adult; Blepharoptosis; Carbimazole; Female; Humans; Myasthenia Gravis; Neostigmine; Prednisolone; Th

1991
[Immunologically active preparations in the complex treatment of patients with diffuse toxic goiter].
    Klinicheskaia meditsina, 1988, Volume: 66, Issue:2

    Topics: Adjuvants, Immunologic; Adolescent; Adult; Female; Humans; Levamisole; Male; Middle Aged; Prednisolo

1988