prednisolone has been researched along with Spinal Muscular Atrophies of Childhood in 3 studies
Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.
Spinal Muscular Atrophies of Childhood: A group of recessive inherited diseases that feature progressive muscular atrophy and hypotonia. They are classified as type I (Werdnig-Hoffman disease), type II (intermediate form), and type III (Kugelberg-Welander disease). Type I is fatal in infancy, type II has a late infantile onset and is associated with survival into the second or third decade. Type III has its onset in childhood, and is slowly progressive. (J Med Genet 1996 Apr:33(4):281-3)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this population, with thorough screening and careful post-gene transfer management, replacement therapy with onasemnogene abeparvovec-xioi is safe and shows promise for early efficacy." | 1.56 | Gene Therapy for Spinal Muscular Atrophy: Safety and Early Outcomes. ( Alfano, LN; Bass, N; Broomall, E; Connolly, AM; Ginsberg, M; Goldstein, J; Iammarino, MA; Karingada, C; Lowes, LP; Mendell, JR; Miller, NF; Mosher, KA; Noritz, G; Powers, B; Rossman, I; Storey, MA; Tsao, CY; Waldrop, MA, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 3 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Byon, JH | 1 |
| Park, EH | 1 |
| Lee, CH | 1 |
| Feldman, AG | 1 |
| Parsons, JA | 1 |
| Dutmer, CM | 1 |
| Veerapandiyan, A | 1 |
| Hafberg, E | 1 |
| Maloney, N | 1 |
| Mack, CL | 1 |
| Waldrop, MA | 1 |
| Karingada, C | 1 |
| Storey, MA | 1 |
| Powers, B | 1 |
| Iammarino, MA | 1 |
| Miller, NF | 1 |
| Alfano, LN | 1 |
| Noritz, G | 1 |
| Rossman, I | 1 |
| Ginsberg, M | 1 |
| Mosher, KA | 1 |
| Broomall, E | 1 |
| Goldstein, J | 1 |
| Bass, N | 1 |
| Lowes, LP | 1 |
| Tsao, CY | 1 |
| Mendell, JR | 1 |
| Connolly, AM | 1 |
3 other studies available for prednisolone and Spinal Muscular Atrophies of Childhood
| Article | Year |
|---|---|
Early Diagnosed Hirayama Disease with Unusual Symptoms Improved by Steroid Pulse Therapy.
Topics: Cervical Cord; Drug Administration Schedule; Early Diagnosis; Glucocorticoids; Humans; Magnetic Reso | 2020 |
Subacute Liver Failure Following Gene Replacement Therapy for Spinal Muscular Atrophy Type 1.
Topics: Chemical and Drug Induced Liver Injury; Female; Genetic Therapy; Glucocorticoids; Humans; Infant; Ma | 2020 |
Gene Therapy for Spinal Muscular Atrophy: Safety and Early Outcomes.
Topics: Adenoviruses, Human; Age Factors; Alanine Transaminase; Aspartate Aminotransferases; Biological Prod | 2020 |