Page last updated: 2024-11-06

prednisolone and Spasm

prednisolone has been researched along with Spasm in 22 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Spasm: An involuntary contraction of a muscle or group of muscles. Spasms may involve SKELETAL MUSCLE or SMOOTH MUSCLE.

Research Excerpts

ExcerptRelevanceReference
"To compare the effect and safety of prednisolone and adrenocorticotropic hormone (ACTH) in the treatment of infantile spasms (IS)."9.01[Effect of prednisolone and adrenocorticotropic hormone in the treatment of infantile spasms: a Meta analysis]. ( Luo, KR; Mu, DZ; Tang, J, 2019)
"To report a prospectively planned analysis of two randomised controlled trials with embedded comparisons of prednisolone versus tetracosactide depot for the treatment of infantile epileptic spasms syndrome (IESS)."8.31Prednisolone or tetracosactide depot for infantile epileptic spasms syndrome? A prospective analysis of data embedded within two randomised controlled trials. ( Alber, FD; Edwards, SW; Hancock, E; Johnson, AL; Kennedy, CR; Likeman, M; Lux, AL; Mackay, M; Mallick, A; Newton, RW; Nolan, M; O'Callaghan, FK; Osborne, JP; Pressler, R; Rating, D; Schmitt, B; Verity, CM, 2023)
"To report response to first treatment in infants with infantile spasms (IS), including incremental benefit of prednisolone 60 mg/day and vigabatrin following prednisolone 40 mg/day failure in infants commenced on the United Kingdom Infantile Spasms Study (UKISS) treatment sequence."8.12Response to sequential treatment with prednisolone and vigabatrin in infantile spasms. ( Cheng, S; Dzau, W; Fahey, M; Harvey, AS; Howell, KB; Scheffer, IE; Snell, P, 2022)
"BACKGROUND: High-dose prednisone and prednisolone have been increasingly studied as a lower-cost alternative to adrenocorticotropic hormone for the treatment of infantile spasms, but this treatment has not been well studied in children with infantile spasms due to perinatal stroke."8.02High-Dose Prednisolone for Treatment of Infantile Spasms After Presumed Perinatal Stroke. ( Golomb, MR; Hall, KR, 2021)
"To evaluate the clinical profile and response to oral prednisolone in infantile spasms."7.76Clinical profile and response to oral prednisolone in infantile spasm. ( Noureen, N; Rana, MT, 2010)
"To compare the effect and safety of prednisolone and adrenocorticotropic hormone (ACTH) in the treatment of infantile spasms (IS)."5.01[Effect of prednisolone and adrenocorticotropic hormone in the treatment of infantile spasms: a Meta analysis]. ( Luo, KR; Mu, DZ; Tang, J, 2019)
"To describe the temporal trends in the cost and use of adrenocorticotropic hormone (ACTH), oral prednisolone, and vigabatrin, the first-line treatments for infantile epileptic spasms syndrome (IESS)."4.31Temporal trends in the cost and use of first-line treatments for infantile epileptic spasms syndrome. ( Amengual-Gual, M; Barcia Aguilar, C; Chao, J; Douglass, L; Gaínza-Lein, M; Harini, C; Jonas, R; Romeu, A; Sánchez Fernández, I; Sheikh, T; Torres, A, 2023)
"To report a prospectively planned analysis of two randomised controlled trials with embedded comparisons of prednisolone versus tetracosactide depot for the treatment of infantile epileptic spasms syndrome (IESS)."4.31Prednisolone or tetracosactide depot for infantile epileptic spasms syndrome? A prospective analysis of data embedded within two randomised controlled trials. ( Alber, FD; Edwards, SW; Hancock, E; Johnson, AL; Kennedy, CR; Likeman, M; Lux, AL; Mackay, M; Mallick, A; Newton, RW; Nolan, M; O'Callaghan, FK; Osborne, JP; Pressler, R; Rating, D; Schmitt, B; Verity, CM, 2023)
"Prednisolone is an effective and well-tolerated medication for treating infantile spasms in Down syndrome."4.12Response to treatment and outcomes of infantile spasms in Down syndrome. ( Allen, NM; Gorman, KM; Harvey, S; King, MD; Lynch, B; Lynch, SA; O'Regan, M; O'Rourke, D; Shahwan, A; Webb, D, 2022)
"To report response to first treatment in infants with infantile spasms (IS), including incremental benefit of prednisolone 60 mg/day and vigabatrin following prednisolone 40 mg/day failure in infants commenced on the United Kingdom Infantile Spasms Study (UKISS) treatment sequence."4.12Response to sequential treatment with prednisolone and vigabatrin in infantile spasms. ( Cheng, S; Dzau, W; Fahey, M; Harvey, AS; Howell, KB; Scheffer, IE; Snell, P, 2022)
"BACKGROUND: High-dose prednisone and prednisolone have been increasingly studied as a lower-cost alternative to adrenocorticotropic hormone for the treatment of infantile spasms, but this treatment has not been well studied in children with infantile spasms due to perinatal stroke."4.02High-Dose Prednisolone for Treatment of Infantile Spasms After Presumed Perinatal Stroke. ( Golomb, MR; Hall, KR, 2021)
"To evaluate the clinical profile and response to oral prednisolone in infantile spasms."3.76Clinical profile and response to oral prednisolone in infantile spasm. ( Noureen, N; Rana, MT, 2010)
"It has been known that West syndrome (WS) patients with an unknown etiology have better clinical outcomes than patients with an identified etiology of any kind."1.62Disparate treatment outcomes according to presence of pathogenic mutations in West syndrome. ( Choi, HS; Choi, JR; Kang, HC; Kim, HD; Kim, SH; Ko, A; Lee, JS; Lee, ST, 2021)
"Prednisolone treatment alone was not successful."1.33Satoyoshi syndrome: a rare multisystemic disorder requiring systemic and symptomatic treatment. ( Heger, S; Kuester, RM; Sippell, WG; Stephani, U; Volk, R, 2006)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19906 (27.27)18.7374
1990's0 (0.00)18.2507
2000's3 (13.64)29.6817
2010's5 (22.73)24.3611
2020's8 (36.36)2.80

Authors

AuthorsStudies
Harvey, S1
Allen, NM1
King, MD1
Lynch, B1
Lynch, SA1
O'Regan, M1
O'Rourke, D1
Shahwan, A1
Webb, D1
Gorman, KM1
Dzau, W1
Cheng, S1
Snell, P1
Fahey, M1
Scheffer, IE1
Harvey, AS1
Howell, KB1
Sánchez Fernández, I1
Amengual-Gual, M1
Barcia Aguilar, C1
Romeu, A1
Sheikh, T1
Torres, A1
Chao, J1
Jonas, R1
Gaínza-Lein, M1
Harini, C1
Douglass, L1
Osborne, JP1
Edwards, SW1
Alber, FD1
Hancock, E1
Johnson, AL1
Kennedy, CR1
Likeman, M1
Lux, AL1
Mackay, M1
Mallick, A1
Newton, RW1
Nolan, M1
Pressler, R1
Rating, D1
Schmitt, B1
Verity, CM1
O'Callaghan, FK1
Sampaio, LPB1
Henriques-Souza, AMM1
Silveira, MRMD1
Seguti, L1
Santos, MLSF1
Montenegro, MA1
Antoniuk, S1
Manreza, MLG1
Shen, D1
Zhou, H1
Chen, S1
Hall, KR1
Golomb, MR1
Choi, HS1
Ko, A1
Kim, SH1
Lee, ST1
Choi, JR1
Lee, JS1
Kim, HD1
Kang, HC1
Gowda, VK1
Narayanaswamy, V1
Shivappa, SK1
Benakappa, N1
Benakappa, A1
Luo, KR1
Tang, J1
Mu, DZ1
Tiwari, L1
Kumar, M1
Noureen, N1
Rana, MT1
Mukhopadhyay, D1
Ghosh, A1
Mukhopadhyay, M1
Endo, K1
Yamamoto, T1
Nakamura, K1
Hoshi, A1
Yamanoi, T1
Watanabe, A1
Homma, M1
FUELOEP, T1
KAISER, E1
FARKAS, G1
KONDO, T1
FUEKI, R1
AOKI, M1
MAKIMOTO, H1
Ashalatha, R1
Kishore, A1
Sarada, C1
Nair, MD1
Heger, S1
Kuester, RM1
Volk, R1
Stephani, U1
Sippell, WG1
Matsumoto, H1
Shibata, K1
Suga, M1
Ito, M1
Yachi, A1
Rechlin, R1
Rossberg, B1
Reinschke, P1
Gudowski, G1
Parsonage, M1
Danielsen, J1

Reviews

2 reviews available for prednisolone and Spasm

ArticleYear
[Effect of prednisolone and adrenocorticotropic hormone in the treatment of infantile spasms: a Meta analysis].
    Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2019, Volume: 21, Issue:7

    Topics: Adrenocorticotropic Hormone; Anticonvulsants; China; Humans; Infant; Prednisolone; Spasm; Spasms, In

2019
[Problems of juvenile poisoning (Ingestion accidents)].
    Zeitschrift fur arztliche Fortbildung, 1978, Oct-15, Volume: 72, Issue:20

    Topics: Aftercare; Anti-Bacterial Agents; Antidotes; Burns, Chemical; Child; Child, Preschool; Diazepam; Exc

1978

Trials

1 trial available for prednisolone and Spasm

ArticleYear
Corticotrophin-ACTH in Comparison to Prednisolone in West Syndrome - A Randomized Study.
    Indian journal of pediatrics, 2019, Volume: 86, Issue:2

    Topics: Adrenocorticotropic Hormone; Child, Preschool; Drug-Related Side Effects and Adverse Reactions; Epil

2019

Other Studies

19 other studies available for prednisolone and Spasm

ArticleYear
Response to treatment and outcomes of infantile spasms in Down syndrome.
    Developmental medicine and child neurology, 2022, Volume: 64, Issue:6

    Topics: Adult; Anticonvulsants; Child; Down Syndrome; Humans; Infant; Prednisolone; Seizures; Spasm; Spasms,

2022
Response to sequential treatment with prednisolone and vigabatrin in infantile spasms.
    Journal of paediatrics and child health, 2022, Volume: 58, Issue:12

    Topics: Anticonvulsants; Humans; Infant; Prednisolone; Recurrence; Retrospective Studies; Spasm; Spasms, Inf

2022
Temporal trends in the cost and use of first-line treatments for infantile epileptic spasms syndrome.
    Epilepsia, 2023, Volume: 64, Issue:3

    Topics: Adrenocorticotropic Hormone; Anticonvulsants; Child; Female; Humans; Infant; Infant, Newborn; Male;

2023
Prednisolone or tetracosactide depot for infantile epileptic spasms syndrome? A prospective analysis of data embedded within two randomised controlled trials.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2023, Volume: 42

    Topics: Anticonvulsants; Cosyntropin; Epilepsy; Humans; Infant; Prednisolone; Randomized Controlled Trials a

2023
Brazilian experts' consensus on the treatment of infantile epileptic spasm syndrome in infants.
    Arquivos de neuro-psiquiatria, 2023, Volume: 81, Issue:9

    Topics: Anticonvulsants; Brazil; Child; Consensus; Epilepsy; Humans; Infant; Prednisolone; Recurrence; Spasm

2023
Spasms and Myoclonus in a Young Woman With Hashimoto Thyroiditis.
    JAMA neurology, 2020, 05-01, Volume: 77, Issue:5

    Topics: Adult; Anticonvulsants; Clonazepam; Diazepam; Encephalomyelitis; Female; Hashimoto Disease; Humans;

2020
High-Dose Prednisolone for Treatment of Infantile Spasms After Presumed Perinatal Stroke.
    The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses, 2021, Apr-01, Volume: 53, Issue:2

    Topics: Child; Female; Humans; Infant; Prednisolone; Spasm; Spasms, Infantile; Stroke; Treatment Outcome

2021
Disparate treatment outcomes according to presence of pathogenic mutations in West syndrome.
    Epilepsia, 2021, Volume: 62, Issue:7

    Topics: Age of Onset; Anti-Inflammatory Agents; Anticonvulsants; Arrhythmias, Cardiac; Child; Child, Prescho

2021
Oral Prednisolone Versus Intramuscular Corticotropin in West Syndrome.
    Pediatric neurology, 2016, Volume: 64

    Topics: Adrenocorticotropic Hormone; Humans; Injections, Intramuscular; Prednisolone; Single-Blind Method; S

2016
Clinical profile and response to oral prednisolone in infantile spasm.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2010, Volume: 20, Issue:3

    Topics: Electroencephalography; Female; Glucocorticoids; Humans; Infant; Male; Prednisolone; Spasm; Tomograp

2010
Satoyoshi syndrome.
    Indian pediatrics, 2011, Volume: 48, Issue:9

    Topics: Alopecia; Bone and Bones; Child; Diarrhea; Female; Humans; Phenytoin; Prednisolone; Spasm; Vitamin D

2011
Improvement of Satoyoshi syndrome with tacrolimus and corticosteroids.
    Neurology, 2003, Jun-24, Volume: 60, Issue:12

    Topics: Adolescent; Alopecia; Amenorrhea; Autoantibodies; Autoimmune Diseases; Drug Therapy, Combination; Fe

2003
[TREATMENT OF HYPSARRHYTHMIA ASSOCIATED WITH FLEXOR SPASM WITH ACTH AND PREDNISOLONE].
    Orvosi hetilap, 1964, Mar-15, Volume: 105

    Topics: Adolescent; Adrenocorticotropic Hormone; Asphyxia Neonatorum; Child; Down Syndrome; Electroencephalo

1964
[AUTOPSY CASE OF BRONCHIAL ASTHMA WITH DEATH DURING A SPASM].
    Naika. Internal medicine, 1964, Volume: 14

    Topics: Adrenocorticotropic Hormone; Aminophylline; Asthma; Autopsy; Chlordiazepoxide; Death; Death, Sudden;

1964
Satoyoshi syndrome.
    Neurology India, 2004, Volume: 52, Issue:1

    Topics: Adult; Alopecia; Anemia, Hemolytic; Anticonvulsants; Autoimmune Diseases; Electromyography; Endocrin

2004
Satoyoshi syndrome: a rare multisystemic disorder requiring systemic and symptomatic treatment.
    Brain & development, 2006, Volume: 28, Issue:5

    Topics: Adult; Bone Diseases, Developmental; Carbamazepine; Drug Therapy, Combination; Endocrine System Dise

2006
[A case of brain stem encephalitis with complete recovery (Bickerstaff's encephalitis)].
    No to shinkei = Brain and nerve, 1984, Volume: 36, Issue:6

    Topics: Adolescent; Antibodies, Viral; Brain Stem; Complement Fixation Tests; Electroencephalography; Enceph

1984
Epilepsy.
    The Practitioner, 1974, Volume: 213, Issue:1276 SPEC

    Topics: Adrenocorticotropic Hormone; Carbamazepine; Diazepam; Drug Hypersensitivity; Drug-Related Side Effec

1974
Infantile spasms and hypsarhythmia treated with corticosteroids.
    Acta neurologica Scandinavica. Supplementum, 1965, Volume: 13 Pt 2

    Topics: Adrenocorticotropic Hormone; Brain Diseases; Cerebral Ventriculography; Electroencephalography; Huma

1965