prednisolone has been researched along with Shock, Septic in 50 studies
Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.
Shock, Septic: Sepsis associated with HYPOTENSION or hypoperfusion despite adequate fluid resuscitation. Perfusion abnormalities may include but are not limited to LACTIC ACIDOSIS; OLIGURIA; or acute alteration in mental status.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We encountered a disseminated sporotrichosis patient with polyarthritis and progressive skin ulcers, who had been previously treated with prednisolone, tocilizmab, tacrolims, and cyclophosphamide under the diagnosis of rheumatoid arthritis in another hospital." | 7.78 | A case of disseminated sporotrichosis treated with prednisolone, immunosuppressants, and tocilizumab under the diagnosis of rheumatoid arthritis. ( Goto, D; Goto, M; Hayashi, T; Horikoshi, M; Ito, S; Matsumoto, I; Sumida, T; Takano, Y; Umeda, N; Yamaguchi, T, 2012) |
| " The IV injection of prednisolone sodium succinate, 10 mg/kg at 25 minutes before dosing the pigs with endotoxin resulted in a significant increase in survival time." | 5.27 | Endotoxin shock in the pig: beneficial effects of pretreatment with prednisolone sodium succinate. ( Houvenaghel, AM; Schrauwen, EM, 1984) |
| "We encountered a disseminated sporotrichosis patient with polyarthritis and progressive skin ulcers, who had been previously treated with prednisolone, tocilizmab, tacrolims, and cyclophosphamide under the diagnosis of rheumatoid arthritis in another hospital." | 3.78 | A case of disseminated sporotrichosis treated with prednisolone, immunosuppressants, and tocilizumab under the diagnosis of rheumatoid arthritis. ( Goto, D; Goto, M; Hayashi, T; Horikoshi, M; Ito, S; Matsumoto, I; Sumida, T; Takano, Y; Umeda, N; Yamaguchi, T, 2012) |
| "We investigated the effect of a novel N-benzoyl-L-phenylalanine derivative compound (JTE-607) on production of various cytokines and other immune responses in vitro and on endotoxin shock in vivo." | 3.70 | JTE-607, a novel inflammatory cytokine synthesis inhibitor without immunosuppression, protects from endotoxin shock in mice. ( Iwamura, H; Kakutani, M; Takeuchi, K; Waga, I; Wakitani, K, 1999) |
| "To evaluate the effect of certain drugs on hematologic changes, blood chemical values, and survival in endotoxin shock, anesthetized ponies were given (IV) endotoxin (Escherichia coli O55:B5) and then treated as follows: Group A ponies--given a saline infusion at 5 minutes and at 3 hours after they were given endotoxin; group B ponies--given flunixin meglumine at 5 minutes and at 3, 6, 9, and 24 hours after they were given endotoxin; group C ponies--treated with dexamethasone; and group D ponies--treated with prednisolone at 5 minutes and at 3, 9, and 24 hours after they were given endotoxin." | 3.67 | Endotoxin-induced hematologic and blood chemical changes in ponies: effects of flunixin meglumine, dexamethasone, and prednisolone. ( Bottoms, GD; Ewert, KM; Fessler, JF; Johnson, MA; Latshaw, HS; Templeton, CB, 1985) |
| "The terms corticosteroids, sepsis, septic shock, hydrocortisone, controlled trials, and randomized controlled trial were searched alone or in combination." | 2.61 | Association of Corticosteroid Treatment With Outcomes in Adult Patients With Sepsis: A Systematic Review and Meta-analysis. ( Fang, F; Faramand, A; He, J; Li, T; Lunsford, LD; Tang, J; Tang, R; Xu, J; Xu, P; You, C; Zhang, Y, 2019) |
| " Heterogeneity was related in part to the dosing strategy." | 2.52 | Corticosteroids for treating sepsis. ( Annane, D; Bellissant, E; Bollaert, PE; Briegel, J; Keh, D; Kupfer, Y, 2015) |
| "Most patients were on corticosteroid treatment." | 2.43 | Necrotizing fasciitis in rheumatic diseases. ( Chan, TM; Lau, CS; Mok, MY; Tang, WM; Wong, SY; Wong, WS, 2006) |
| "In the septic shock model, all three drugs given preventively markedly decreased circulating levels of TNF-alpha and mortality (50% mortality in fluoxetine treated group, 30% in desipramine and prednisolone treated groups versus 90% in controls)." | 1.34 | Anti-inflammatory properties of desipramine and fluoxetine. ( Bichon, F; Detoc, M; Henriquet, C; Jaffuel, D; Mathieu, M; Michel, A; Portet, K; Roumestan, C, 2007) |
| "We have developed a septic shock model in mice by sequential administration of beta-glucan, a biological response modifier, and indomethacin (IND), a nonsteroidal anti-inflammatory drug." | 1.34 | Lincomycin protects mice from septic shock in beta-glucan-indomethacin model. ( Adachi, Y; Miura, NN; Nameda, S; Ohno, N, 2007) |
| "Septic shock is characterised by infection causing a systemic inflammatory response, end-organ failure and acute circulatory collapse." | 1.30 | Sweet's syndrome associated with systemic inflammatory response syndrome. ( Matthews, PC; Willatts, SM, 1998) |
| " The IV injection of prednisolone sodium succinate, 10 mg/kg at 25 minutes before dosing the pigs with endotoxin resulted in a significant increase in survival time." | 1.27 | Endotoxin shock in the pig: beneficial effects of pretreatment with prednisolone sodium succinate. ( Houvenaghel, AM; Schrauwen, EM, 1984) |
| " This lack of effect can be due to an inappropriate dosage of the steroid or failure of steroid treatment to alleviate endotoxin-mediated effects." | 1.27 | Endotoxic shock in the awake young pig: absence of beneficial effect of prednisolone sodium succinate treatment. ( Houvenaghel, AM; Schrauwen, EM, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 35 (70.00) | 18.7374 |
| 1990's | 2 (4.00) | 18.2507 |
| 2000's | 8 (16.00) | 29.6817 |
| 2010's | 5 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fang, F | 1 |
| Zhang, Y | 1 |
| Tang, J | 1 |
| Lunsford, LD | 1 |
| Li, T | 1 |
| Tang, R | 1 |
| He, J | 1 |
| Xu, P | 1 |
| Faramand, A | 1 |
| Xu, J | 1 |
| You, C | 1 |
| Jamieson, A | 1 |
| Parkins, G | 1 |
| White, B | 1 |
| Annane, D | 2 |
| Bellissant, E | 1 |
| Bollaert, PE | 1 |
| Briegel, J | 1 |
| Keh, D | 1 |
| Kupfer, Y | 1 |
| Wyska, E | 1 |
| Yamaguchi, T | 1 |
| Ito, S | 1 |
| Takano, Y | 1 |
| Umeda, N | 1 |
| Goto, M | 1 |
| Horikoshi, M | 1 |
| Hayashi, T | 1 |
| Goto, D | 1 |
| Matsumoto, I | 1 |
| Sumida, T | 1 |
| MURANAKA, M | 1 |
| ABE, K | 1 |
| HAZEYAMA, S | 1 |
| KURAJIMA, S | 1 |
| SAMBHI, MP | 1 |
| WEIL, MH | 1 |
| UDHOJI, VN | 1 |
| SHUBIN, H | 1 |
| Iwamura, H | 2 |
| Sato, M | 1 |
| Wakitani, K | 2 |
| Kotanidou, AN | 1 |
| Zakynthinos, E | 1 |
| Andrianakis, I | 1 |
| Zervakis, D | 1 |
| Kokotsakis, I | 1 |
| Argyrakos, T | 1 |
| Argiropoulou, A | 1 |
| Margariti, G | 1 |
| Douzinas, E | 1 |
| Mok, MY | 1 |
| Wong, SY | 1 |
| Chan, TM | 1 |
| Tang, WM | 1 |
| Wong, WS | 1 |
| Lau, CS | 1 |
| Amano, T | 1 |
| Nishihira, J | 1 |
| Miki, I | 1 |
| Roumestan, C | 1 |
| Michel, A | 1 |
| Bichon, F | 1 |
| Portet, K | 1 |
| Detoc, M | 1 |
| Henriquet, C | 1 |
| Jaffuel, D | 1 |
| Mathieu, M | 1 |
| Nameda, S | 1 |
| Miura, NN | 1 |
| Adachi, Y | 1 |
| Ohno, N | 1 |
| Renaud, S | 1 |
| Allard, C | 1 |
| Latour, JG | 1 |
| Sekigawa, T | 1 |
| Schrauwen, EM | 2 |
| Houvenaghel, AM | 2 |
| Brückner, O | 1 |
| Kresse, M | 1 |
| Neubert, V | 1 |
| Triest, H | 1 |
| Trautmann, M | 1 |
| Roland, DA | 1 |
| Mora, EC | 1 |
| Hoerr, FJ | 1 |
| White, GL | 1 |
| White, GS | 1 |
| Richter, K | 1 |
| Bowen, JM | 1 |
| Matthews, PC | 1 |
| Willatts, SM | 1 |
| Kakutani, M | 1 |
| Takeuchi, K | 1 |
| Waga, I | 1 |
| Emerson, TE | 1 |
| Katsu, M | 1 |
| Mita, S | 1 |
| Soma, T | 1 |
| Adachi, M | 1 |
| Hankes, GH | 1 |
| Templeton, CB | 2 |
| Bottoms, GD | 2 |
| Fessler, JF | 2 |
| Ewert, KM | 2 |
| Roesel, OF | 1 |
| Johnson, MA | 2 |
| Latshaw, HS | 2 |
| Bahrami, S | 1 |
| Schiesser, A | 1 |
| Redl, H | 1 |
| Schlag, G | 1 |
| Ho, CH | 1 |
| Chiang, YM | 1 |
| Chong, LL | 1 |
| Lin, HY | 1 |
| Hwang, TS | 1 |
| Wittels, W | 1 |
| Bartel, J | 3 |
| Bornemann, K | 1 |
| Schulz, E | 1 |
| Heinecker, R | 1 |
| Martin, L | 1 |
| Anton, AH | 1 |
| Huth, K | 1 |
| Missler, U | 1 |
| Schmahl, FW | 1 |
| Beickert, A | 1 |
| Mills, LC | 1 |
| Jaques, R | 1 |
| Jaquet, H | 1 |
| Vaughn, D | 1 |
| Kirschbaum, TH | 1 |
| Bersentes, T | 1 |
| Assali, NS | 1 |
| Luger, A | 1 |
| Pavlik, F | 1 |
| Dieckhoff, J | 2 |
| Gawellek, F | 1 |
| Iwanoff, S | 1 |
| Hoppe, E | 1 |
| Schimpf, K | 1 |
| Krecke, HJ | 1 |
| Herbig, W | 1 |
| Sullivan, TJ | 1 |
| Cavanagh, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Outcomes of Metabolic Resuscitation Using Ascorbic Acid, Thiamine, and Glucocorticoids in the Early Treatment of Sepsis.[NCT03422159] | Phase 2 | 140 participants (Actual) | Interventional | 2018-02-05 | Completed | ||
| Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock: a Randomized Clinical Study (VITAMIN TRIAL)[NCT05192213] | Phase 3 | 1,090 participants (Anticipated) | Interventional | 2021-08-01 | Recruiting | ||
| Fluoxetine to Reduce Hospitalization From COVID-19 Infection (FloR COVID-19)[NCT04570449] | Early Phase 1 | 0 participants (Actual) | Interventional | 2020-11-30 | Withdrawn (stopped due to Study timeline is not feasible) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Defined as the day 4 post-randomization SOFA score minus the initial SOFA score. The Sequential Organ Failure Assessment (SOFA) Score is a mortality prediction score that is based on the degree of dysfunction of six organ systems. The score is calculated on admission and every 24 hours until discharge using the worst parameters measured during the prior 24 hours SOFA score ranges from 0 (no organ dysfunction) to 24 (highest possible score / organ dysfunction). (NCT03422159)
Timeframe: 4 days post-randomization
| Intervention | score on a scale (Mean) |
|---|---|
| Treatment Arm | 2.9 |
| Placebo Arm | 1.93 |
Time from admitting to discharge of hospital stay. (NCT03422159)
Timeframe: From admission to the hospital until final discharge, up to 28 days.
| Intervention | Days (Mean) |
|---|---|
| Treatment Arm | 11.5 |
| Placebo Arm | 11 |
In-hospital mortality rate. (NCT03422159)
Timeframe: Survival until hospital discharge, up to 28 days.
| Intervention | Participants (Count of Participants) |
|---|---|
| Treatment Arm | 11 |
| Placebo Arm | 13 |
Time from admitting to ICU to discharge. (NCT03422159)
Timeframe: From admission to the ICU until final discharge from the ICU, up to an average of 7 days.
| Intervention | days (Mean) |
|---|---|
| Treatment Arm | 4.76 |
| Placebo Arm | 4.66 |
ICU mortality rate (NCT03422159)
Timeframe: From admission to hospital until final discharge from the ICU, up to 28 days.
| Intervention | Participants (Count of Participants) |
|---|---|
| Treatment Arm | 6 |
| Placebo Arm | 10 |
PCT at 96 hours minus initial PCT, divided by the initial PCT multiplied by 100. (NCT03422159)
Timeframe: 4 days post-randomization
| Intervention | Percent (Mean) |
|---|---|
| Treatment Arm | 63 |
| Placebo Arm | 58 |
Defined as the time from starting the active treatment/placebo to discontinuation of all pressors. (NCT03422159)
Timeframe: From start of vasopressor medication to final discontinuation of vasopressor medication, up to 7 days.
| Intervention | hours (Mean) |
|---|---|
| HAT Treatment | 27 |
| Comparator | 53 |
Number of days alive and off of the ventilator at day 28. (NCT03422159)
Timeframe: 28 Days post-randomization
| Intervention | Days (Mean) |
|---|---|
| Treatment Arm | 22 |
| Placebo Arm | 22.4 |
7 reviews available for prednisolone and Shock, Septic
| Article | Year |
|---|---|
Association of Corticosteroid Treatment With Outcomes in Adult Patients With Sepsis: A Systematic Review and Meta-analysis.
Topics: Adrenal Cortex Hormones; Adult; Glucocorticoids; Humans; Hydrocortisone; Intensive Care Units; Organ | 2019 |
Corticosteroids for treating sepsis.
Topics: Adrenal Cortex Hormones; Adult; Child; Critical Care; Dexamethasone; Fludrocortisone; Humans; Hydroc | 2015 |
Corticosteroids for treating sepsis.
Topics: Adrenal Cortex Hormones; Adult; Child; Critical Care; Dexamethasone; Fludrocortisone; Humans; Hydroc | 2015 |
Corticosteroids for treating sepsis.
Topics: Adrenal Cortex Hormones; Adult; Child; Critical Care; Dexamethasone; Fludrocortisone; Humans; Hydroc | 2015 |
Corticosteroids for treating sepsis.
Topics: Adrenal Cortex Hormones; Adult; Child; Critical Care; Dexamethasone; Fludrocortisone; Humans; Hydroc | 2015 |
Aspergillus endocarditis in a native valve after amphotericin B treatment.
Topics: Amphotericin B; Anti-Infective Agents; Aspergillosis; Aspergillus fumigatus; Candidiasis; Drug Resis | 2004 |
Necrotizing fasciitis in rheumatic diseases.
Topics: Adult; Aeromonas; Animals; Anti-Bacterial Agents; Arthritis, Infectious; Arthritis, Rheumatoid; Arth | 2006 |
Therapy of shock: the corticosteroid question.
Topics: Adrenal Cortex Hormones; Animals; Cardiac Output; Cell Membrane; Dexamethasone; Dog Diseases; Dogs; | 1976 |
[Pathogenesis of the septic-toxic shock].
Topics: Animals; Autolysis; Capillary Permeability; Cardiac Output; Cathepsins; Disseminated Intravascular C | 1972 |
[Glucocorticoids in prophylaxis and therapy of different kinds of shock].
Topics: Anaphylaxis; Anti-Bacterial Agents; Cardiac Glycosides; Dexamethasone; Dextrans; Epinephrine; Glucoc | 1970 |
43 other studies available for prednisolone and Shock, Septic
| Article | Year |
|---|---|
Drugs, the Thyroid, and the Heart: A Lethal Cocktail.
Topics: Agranulocytosis; Amiodarone; Anti-Arrhythmia Agents; Antithyroid Agents; Atrial Fibrillation; Carbim | 2019 |
DRESS syndrome presenting like septic shock.
Topics: Adult; Diagnosis, Differential; Drug Eruptions; Drug Hypersensitivity Syndrome; Drug-Related Side Ef | 2013 |
Pretreatment with R(+)-verapamil significantly reduces mortality and cytokine expression in murine model of septic shock.
Topics: Animals; Anti-Inflammatory Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytokine | 2009 |
A case of disseminated sporotrichosis treated with prednisolone, immunosuppressants, and tocilizumab under the diagnosis of rheumatoid arthritis.
Topics: Aged; Antibodies, Monoclonal, Humanized; Arthritis, Infectious; Arthritis, Rheumatoid; Diagnosis, Di | 2012 |
[SHOCK-LIKE SYMPTOMS CAUSED BY DRUGS AND THEIR TREATMENT. (2) CLINICAL ASPECTS].
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Aspirin; Blood Chemical Analysis; Body Constitut | 1963 |
[CASE OF SYMPTOMS OF SHOCK MANIFESTED AFTER EAR IRRIGATION WITH COLISTIN AND PREDONINE].
Topics: Colistin; Drug Hypersensitivity; Otitis Media; Prednisolone; Shock; Shock, Septic; Therapeutic Irrig | 1963 |
ADRENOCORTICOIDS IN THE MANAGEMENT OF SHOCK.
Topics: Adrenal Cortex Hormones; Aldosterone; Blood Circulation; Dexamethasone; Endotoxins; Humans; Hypotens | 1964 |
Comparative study of glucocorticoids, cyclosporine A, and JTE-607 [(-)-Ethyl-N[3,5-dichloro-2-hydroxy-4-[2-(4-methylpiperazin-1-yl)ethoxy]benzoyl]-L-phenylalaninate dihydrochloride] in a mouse septic shock model.
Topics: Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Cyclosporine; Cytokines; Enzyme-Lin | 2004 |
Blockade of macrophage migration inhibitory factor (MIF) prevents the antigen-induced response in a murine model of allergic airway inflammation.
Topics: Animals; Anti-Inflammatory Agents; Antibodies, Blocking; Asthma; Bronchial Hyperreactivity; Bronchoa | 2007 |
Anti-inflammatory properties of desipramine and fluoxetine.
Topics: Animals; Anti-Inflammatory Agents; Antidepressive Agents; Asthma; Cells, Cultured; Cytokines; Desipr | 2007 |
Lincomycin protects mice from septic shock in beta-glucan-indomethacin model.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; beta-Glucans; Blood Glucose | 2007 |
Prohormones: novel biomarkers for corticosteroids in septic shock?
Topics: Adrenomedullin; Atrial Natriuretic Factor; Biomarkers; Endotoxemia; Glucocorticoids; Hormones; Human | 2008 |
The prevention by glucocorticoids of endotoxin-initiated thrombosis in rat, in relation to fibrinolysis, coagulation, and lipemia.
Topics: Adrenal Cortex Hormones; Animals; Blood Coagulation; Budd-Chiari Syndrome; Fibrinolysis; Humans; Hyd | 1966 |
[Biochemical aspects of endotoxicosis in rat: lipid peroxide formation and the effect of free radical scavengers].
Topics: Animals; Endotoxins; Escherichia coli; Glutathione; Lipid Peroxides; Liver; Lung; Male; Prednisolone | 1984 |
Endotoxin shock in the pig: beneficial effects of pretreatment with prednisolone sodium succinate.
Topics: Animals; Cardiovascular System; Female; Prednisolone; Shock, Septic; Swine; Swine Diseases; Time Fac | 1984 |
[Toxic shock syndrome].
Topics: Adult; Female; Humans; Menstrual Hygiene Products; Prednisolone; Shock, Septic; Staphylococcus aureu | 1983 |
Toxic shock-like syndrome in hens and its relationship to shell-less eggs.
Topics: Animals; Calcification, Physiologic; Chickens; Cyclophosphamide; Disease Models, Animal; Egg Shell; | 1984 |
In vitro effects of prednisolone sodium succinate and Escherichia coli organisms on neutrophil survival, glucose utilization, and E coli clearance in canine blood.
Topics: Animals; Blood Glucose; Cell Survival; Dogs; Endotoxins; Escherichia coli; Escherichia coli Infectio | 1982 |
[Children's emergencies--what to do?].
Topics: Abdomen, Acute; Aerosols; Child, Preschool; Chloral Hydrate; Cold Temperature; Coma; Croup; Diazepam | 1982 |
Are corticosteroids useful in shock therapy?
Topics: Adrenal Cortex Hormones; Animals; Animals, Domestic; Anti-Bacterial Agents; Dexamethasone; Hydrocort | 1980 |
Sweet's syndrome associated with systemic inflammatory response syndrome.
Topics: Anti-Inflammatory Agents; Female; Humans; Middle Aged; Prednisolone; Pyelonephritis; Shock, Septic; | 1998 |
JTE-607, a novel inflammatory cytokine synthesis inhibitor without immunosuppression, protects from endotoxin shock in mice.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Genes, MHC Cl | 1999 |
Total and regional cerebral hemodynamic and metabolic abnormalities during endotoxin shock: prevention with methylprednisolone.
Topics: Animals; Brain; Carbon Dioxide; Cerebrovascular Circulation; Dogs; Escherichia coli Infections; Fema | 1978 |
[Steroid therapy for infectious diseases--indications and methods of administration].
Topics: Adult; Female; Glucocorticoids; Humans; Klebsiella Infections; Male; Prednisolone; Shock, Septic | 1979 |
[Recommendations for the prevention and treatment of transfusion reactions].
Topics: Antibody Formation; Blood; Blood Circulation Time; Diuretics; Embolism, Air; Hemolysis; Heparin; Hum | 1976 |
Endotoxin-induced hemodynamic and prostaglandin changes in ponies: effects of flunixin meglumine, dexamethasone, and prednisolone.
Topics: Animals; Clonixin; Dexamethasone; Endotoxins; Epoprostenol; Escherichia coli; Female; Hemodynamics; | 1987 |
Comparison of different corticosteroids in rat endotoxemia.
Topics: Adrenal Cortex Hormones; Animals; Dexamethasone; Disease Models, Animal; Endotoxins; Male; Methylpre | 1987 |
Development of chronic lymphocytic leukaemia in a case of Sjögren's syndrome with systemic lupus erythematosus.
Topics: Aged; B-Lymphocytes; Cephalosporins; Female; Gentamicins; Humans; Leukemia, Lymphoid; Lupus Erythema | 1985 |
Endotoxin-induced hematologic and blood chemical changes in ponies: effects of flunixin meglumine, dexamethasone, and prednisolone.
Topics: Animals; Blood Cell Count; Blood Chemical Analysis; Blood Coagulation Tests; Blood Gas Analysis; Clo | 1985 |
Endotoxic shock in the awake young pig: absence of beneficial effect of prednisolone sodium succinate treatment.
Topics: Animals; Body Temperature; Electrocardiography; Escherichia coli; Female; Hemodynamics; Hydrogen-Ion | 1985 |
[Antibiotics and corticosteroids in the corticosteroids in the treatment of burns].
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Burns; Chloramphenicol; Dexamethasone; Gentamicins; | 1971 |
[Acute, non-allergic reactions following i.m. administration of clemizole-penicillin G and streptomycin].
Topics: Adult; Anaphylaxis; Benzimidazoles; Diagnosis, Differential; Drug Hypersensitivity; Female; Histamin | 1966 |
Toxicity of acids and bases after intraperitoneal injection.
Topics: Acetates; Acids; Alkalies; Analgesics; Anesthetics, Local; Animals; Anti-Bacterial Agents; Body Temp | 1970 |
[Influences of prednisolone on changes in lipid metabolism following endotoxin].
Topics: Animals; Cholesterol; Endotoxins; Fatty Acids, Nonesterified; Injections, Intravenous; Lipid Metabol | 1972 |
Corticosteroids in endotoxic shock.
Topics: Adrenal Cortex Hormones; Animals; Dexamethasone; Endotoxins; Escherichia coli; Hydrocortisone; Letha | 1971 |
[What is your diagnosis?].
Topics: Adult; Amputation, Surgical; Blood Transfusion; Chloramphenicol; Female; Forearm Injuries; Fractures | 1971 |
The duration of action of certain corticosteroids in the acutely adrenalectomized rat as estimated by reference to their protective effect in endotoxin shock.
Topics: Adrenalectomy; Animals; Endotoxins; Hydrocortisone; Mortality; Prednisolone; Rats; Serratia marcesce | 1964 |
Effects of corticosteroid hormones on regional circulation in endotoxin shock.
Topics: Acid-Base Equilibrium; Acidosis; Aldosterone; Animals; Blood Circulation; Blood Flow Velocity; Blood | 1967 |
[Effect of corticosteroids on the Jarisch-Herxheimer reaction].
Topics: Depression, Chemical; Fever; Humans; Neurosyphilis; Penicillins; Prednisolone; Procaine; Shock, Sept | 1971 |
[The effect of prednisolone and redergam on experimental endotoxin shock].
Topics: Animals; Catecholamines; Male; Prednisolone; Rabbits; Reserpine; Shock, Septic | 1967 |
[Therapy of experimental endotoxin shock. II. Morphologic changes in kidneys and adrenals in endotoxin shock under treatment with prednisolone and redergam].
Topics: Adrenal Glands; Animals; Humans; Kidney; Male; Prednisolone; Rabbits; Shock, Septic; Shwartzman Phen | 1968 |
[Contrast media-induced shock. Successful therapy using streptokinase].
Topics: Adult; Blood Pressure; Contrast Media; Female; Fibrinolysis; Humans; Norepinephrine; Plasma Substitu | 1969 |
Corticosteroids in endotoxin shock. Effect on renal vasomotion.
Topics: Animals; Blood Pressure; Dexamethasone; Dogs; Endotoxins; Kidney; Prednisolone; Shock, Septic; Vasom | 1966 |