prednisolone has been researched along with Sensation Disorders in 17 studies
Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.
Sensation Disorders: Disorders of the special senses (i.e., VISION; HEARING; TASTE; and SMELL) or somatosensory system (i.e., afferent components of the PERIPHERAL NERVOUS SYSTEM).
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether addition of low dose prednisolone to multidrug treatment can prevent reaction and nerve function impairment in leprosy." | 5.11 | Steroid prophylaxis for prevention of nerve function impairment in leprosy: randomised placebo controlled trial (TRIPOD 1). ( Anderson, AM; Croft, RP; Nicholls, PG; Richardus, JH; Smith, WC; van Brakel, WH; Withington, SG, 2004) |
| "Prednisolone treatment of sensory impairment of the ulnar and posterior tibial nerves detectable with the monofilament test, but not with the ballpen test, did not improve the long-term outcome in terms of recovery of touch sensibility, not did it reduce the risk of leprosy reactions or nerve function impairment beyond the initial 4-month treatment phase." | 2.71 | The prognostic importance of detecting mild sensory impairment in leprosy: a randomized controlled trial (TRIPOD 2). ( Anderson, AM; Croft, RP; Nicholls, PG; Richardus, JH; Smith, WC; Van Brakel, WH; Withington, SG, 2003) |
| " Safety concerns led to an assessment of adverse events of corticosteroids, based on data of three trials studying prevention of NFI (the TRIPOD study)." | 2.71 | Adverse events of standardized regimens of corticosteroids for prophylaxis and treatment of nerve function impairment in leprosy: results from the 'TRIPOD' trials. ( Anderson, AM; Croft, RP; Nicholls, PG; Richardus, JH; Smith, WC; Van Brakel, WH; Withington, SG, 2003) |
| "Prednisolone treatment was administered orally to patients at 30 mg for 7 days, 15 mg for 4 days, and 5 mg for 3 days." | 2.71 | Efficacy of steroid treatment for sensory impairment after orthognathic surgery. ( Seo, K; Someya, G; Tanaka, Y; Terumitsu, M, 2004) |
| "A 66-year-old woman developed bilateral facial paralysis as well as sensory and motor disturbances of extremities." | 1.38 | [Successful treatment of neuroborreliosis with combined administration of antibiotics and steroids: a case report]. ( Kawachi, I; Nishizawa, M; Shimohata, T; Takado, Y; Tanaka, K, 2012) |
| "The patient was diagnosed with breast carcinoma 4 months after initial presentation and underwent resective surgery, radiotherapy, and hormonotherapy." | 1.35 | Steroid-responsive paraneoplastic demyelinating neuropathy and myelopathy associated with breast carcinoma. ( Abbott, RJ; Qaddoura, B; Rajabally, YA, 2008) |
| "A 35-year-old man with borderline tuberculoid leprosy developed Type I lepra reaction 12 days after anti-leprosy treatment." | 1.32 | Pseudoathetosis in a patient with leprosy. ( Kalita, J; Mahadevan, A; Misra, UK; Shankar, SK, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 11 (64.71) | 29.6817 |
| 2010's | 4 (23.53) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tsukita, K | 1 |
| Miyake, H | 1 |
| Kageyama, T | 1 |
| Suenaga, T | 1 |
| Kanazawa, Y | 1 |
| Hagiwara, N | 1 |
| Matsuo, R | 1 |
| Arakawa, S | 1 |
| Ago, T | 1 |
| Kitazono, T | 1 |
| Uchida, Y | 1 |
| Koike, H | 1 |
| Oguri, T | 1 |
| Kato, H | 1 |
| Yuasa, H | 1 |
| Mitake, S | 1 |
| Makinson, A | 1 |
| Morales, RJ | 1 |
| Basset, D | 1 |
| Bouchaud, O | 1 |
| Verdon, R | 1 |
| Hosseini, H | 1 |
| Le Moing, V | 1 |
| Delaporte, E | 1 |
| Reynes, J | 1 |
| Kuroki, N | 1 |
| Ohyagi, Y | 1 |
| Kawano, Y | 1 |
| Yoshiura, T | 1 |
| Taniwaki, T | 1 |
| Kira, J | 1 |
| Rajabally, YA | 1 |
| Qaddoura, B | 1 |
| Abbott, RJ | 1 |
| Takado, Y | 1 |
| Shimohata, T | 1 |
| Kawachi, I | 1 |
| Tanaka, K | 1 |
| Nishizawa, M | 1 |
| Misra, UK | 1 |
| Kalita, J | 1 |
| Mahadevan, A | 1 |
| Shankar, SK | 1 |
| Van Brakel, WH | 4 |
| Anderson, AM | 4 |
| Withington, SG | 4 |
| Croft, RP | 4 |
| Nicholls, PG | 4 |
| Richardus, JH | 4 |
| Smith, WC | 4 |
| Naafs, B | 1 |
| Yang, YW | 1 |
| Liu, CH | 1 |
| Tsai, CH | 1 |
| Lee, CC | 1 |
| Jou, SB | 1 |
| Seo, K | 1 |
| Tanaka, Y | 1 |
| Terumitsu, M | 1 |
| Someya, G | 1 |
| Shimizu, H | 1 |
| Hujimoto, M | 1 |
| Ohashi, T | 1 |
| Shimizu, T | 1 |
| Atsumi, T | 1 |
| Jiang, J | 1 |
| Watson, JM | 1 |
| Zhang, GC | 1 |
| Wei, XY | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Steroid on Reducing Facial Swelling After Orthognathic Surgery[NCT01431014] | Phase 4 | 56 participants (Actual) | Interventional | 2011-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Measure of facial swelling will be performed using 3-dimensional photogrammetry. The 3d photo acquisition is non-invasive without radiation concern. The images will be taken before and after surgery to measure and compare the degree of facial swelling. Side effects from the steroid use are expected to be low under normal clinical dosage, but will also be monitored. Symptoms of wound infection, psychosis, and prolonged wound healing will be studied. There should be no long term complication, since the steroid use is one single dose. (NCT01431014)
Timeframe: 1 year
| Intervention | ml (Mean) | ||
|---|---|---|---|
| 36 hours postoperatively | 1week postoperatively | 1month postoperatively | |
| "DexamethasoneHigh-dose" | 167.06 | 61.39 | 29.85 |
| "DexamethasoneLow-dose" | 190.73 | 57.62 | 19.34 |
2 reviews available for prednisolone and Sensation Disorders
| Article | Year |
|---|---|
[Successful corticosteroid therapies in a case of acute motor, sensory, autonomic neuropathy after cytomegalovirus infection].
Topics: Acute Disease; Autoantibodies; Autonomic Nervous System Diseases; Biomarkers; Cytomegalovirus Infect | 2015 |
Treatment duration of reversal reaction: a reappraisal. Back to the past.
Topics: Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; L | 2003 |
6 trials available for prednisolone and Sensation Disorders
| Article | Year |
|---|---|
The prognostic importance of detecting mild sensory impairment in leprosy: a randomized controlled trial (TRIPOD 2).
Topics: Adult; Aged; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Fe | 2003 |
Treatment with corticosteroids of long-standing nerve function impairment in leprosy: a randomized controlled trial (TRIPOD 3).
Topics: Adolescent; Adult; Confidence Intervals; Dose-Response Relationship, Drug; Double-Blind Method; Drug | 2003 |
Adverse events of standardized regimens of corticosteroids for prophylaxis and treatment of nerve function impairment in leprosy: results from the 'TRIPOD' trials.
Topics: Adolescent; Adult; Confidence Intervals; Dose-Response Relationship, Drug; Double-Blind Method; Drug | 2003 |
Steroid prophylaxis for prevention of nerve function impairment in leprosy: randomised placebo controlled trial (TRIPOD 1).
Topics: Adolescent; Adult; Anti-Bacterial Agents; Double-Blind Method; Drug Combinations; Glucocorticoids; H | 2004 |
Efficacy of steroid treatment for sensory impairment after orthognathic surgery.
Topics: Administration, Oral; Adolescent; Adult; Analysis of Variance; Cold Temperature; Cranial Nerve Injur | 2004 |
A field trial of detection and treatment of nerve function impairment in leprosy--report from national POD pilot project.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Child; Female; Follow-Up Studies; Humans; Leprosy; Male | 1998 |
9 other studies available for prednisolone and Sensation Disorders
| Article | Year |
|---|---|
[Contrast-enhanced fluid-attenuated inversion recovery magnetic resonance imaging was useful in detecting inflammation of the meninges in neuropsychiatric systemic lupus erythematosus: a case report].
Topics: Contrast Media; Female; Humans; Image Enhancement; Lupus Erythematosus, Systemic; Magnetic Resonance | 2018 |
[Case of intravascular large B-cell lymphoma (IVLBCL) with central nervous system symptoms diagnosed by renal biopsy].
Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; | 2014 |
Diagnostic approaches to imported schistosomal myeloradiculopathy in travelers.
Topics: Adult; Africa; Anthelmintics; Anti-Inflammatory Agents; Cauda Equina; Diagnosis, Differential; Eosin | 2008 |
Acute onset facial numbness.
Topics: Acute Disease; Anti-Inflammatory Agents; Diagnosis, Differential; Humans; Magnetic Resonance Imaging | 2008 |
Steroid-responsive paraneoplastic demyelinating neuropathy and myelopathy associated with breast carcinoma.
Topics: Anti-Inflammatory Agents; Breast Neoplasms; Carcinoma; Disease Progression; Female; Humans; Immunogl | 2008 |
[Successful treatment of neuroborreliosis with combined administration of antibiotics and steroids: a case report].
Topics: Aged; Anti-Bacterial Agents; Biomarkers; Borrelia burgdorferi Group; Ceftriaxone; Doxycycline; Drug | 2012 |
Pseudoathetosis in a patient with leprosy.
Topics: Adult; Anti-Inflammatory Agents; Athetosis; Biopsy; Diagnosis, Differential; Evoked Potentials, Soma | 2003 |
Multifocal acquired demyelinating sensory and motor neuropathy: report of a case and review of the literature.
Topics: Adult; Anti-Inflammatory Agents; Demyelinating Diseases; Diagnosis, Differential; Electric Stimulati | 2004 |
[A case with perineuritis].
Topics: Anti-Inflammatory Agents; Female; Humans; Middle Aged; Neuritis; Peripheral Nerves; Peripheral Nervo | 1996 |