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prednisolone and Radiation Pneumonitis

prednisolone has been researched along with Radiation Pneumonitis in 12 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Radiation Pneumonitis: Inflammation of the lung due to harmful effects of ionizing or non-ionizing radiation.

Research Excerpts

ExcerptRelevanceReference
" He then developed radiation pneumonitis, and prednisolone (PSL) was started."4.12Relapsing polychondritis after treatment with PD-1 blockade. ( Hirai, T; Mizuta, M; Ogimoto, T; Yoshida, H, 2022)
"Radiation pneumonitis is usually a diagnosis of exclusion."2.52Radiation induced lung injury: prediction, assessment and management. ( Giridhar, P; Julka, PK; Mallick, S; Rath, GK, 2015)
"Nine patients suffered from chronic obstructive pulmonary disease (COPD) before treatment, and 18 patients had a smoking history (median pack years: 48)."1.43Inhalative steroids as an individual treatment in symptomatic lung cancer patients with radiation pneumonitis grade II after radiotherapy - a single-centre experience. ( Bremer, M; Christiansen, H; Dickgreber, N; Henkenberens, C; Janssen, S; Lavae-Mokhtari, M; Leni, K; Meyer, A, 2016)
"The case of a patient with metastatic renal cell cancer (RCC) who developed recall pneumonitis on the first cycle of systemic sunitinib treatment is reported here."1.39Early onset recall pneumonitis during targeted therapy with sunitinib. ( Harada, S; Kitsukawa, S; Kozuka, T; Kudo, K; Miyazawa, K; Sukegawa, G; Yamamoto, S; Yonese, J; Yuasa, T, 2013)
"Following wide excision of right breast carcinoma and level III axillary lymph node dissection, whole-breast X-ray irradiation was given, at a dose of 2 Gy per fraction; the total dose was 50 Gy."1.33Avascular necrosis of bilateral femoral head as a result of long-term steroid administration for radiation pneumonitis after tangential irradiation of the breast. ( Araki, N; Hiraoka, M; Kodama, H; Kosaka, Y; Mitsumori, M; Nagata, Y; Yamauchi, C, 2006)
"We studied clinical aspects of radiation pneumonitis from 1983 to 1992."1.29[Clinical study of radiation pneumonitis over 10 years]. ( Akiyama, M; Hori, A; Kawakami, K; Masaki, H; Nagatake, T; Ohishi, K; Suga, A; Takahashi, A; Tsuchihashi, Y; Watanabe, H, 1995)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's3 (25.00)18.2507
2000's2 (16.67)29.6817
2010's4 (33.33)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Ogimoto, T1
Yoshida, H1
Mizuta, M1
Hirai, T1
Werner, EM1
Eggert, MC1
Bohnet, S1
Rades, D1
Katsui, K1
Ogata, T1
Watanabe, K1
Katayama, N1
Kuroda, M1
Kiura, K1
Hiraki, T1
Maeda, Y1
Toyooka, S1
Kanazawa, S1
Giridhar, P1
Mallick, S1
Rath, GK1
Julka, PK1
Henkenberens, C1
Janssen, S1
Lavae-Mokhtari, M1
Leni, K1
Meyer, A1
Christiansen, H1
Bremer, M1
Dickgreber, N1
Yuasa, T1
Kitsukawa, S1
Sukegawa, G1
Yamamoto, S1
Kudo, K1
Miyazawa, K1
Kozuka, T1
Harada, S1
Yonese, J1
DOUGLAS, AC1
Akita, K1
Ikawa, A1
Shimizu, S1
Tsuboi, K1
Ishihara, K1
Sato, S1
Ueda, R1
Kosaka, Y1
Mitsumori, M1
Araki, N1
Yamauchi, C1
Nagata, Y1
Hiraoka, M1
Kodama, H1
Watanabe, H1
Suga, A1
Tsuchihashi, Y1
Hori, A1
Kawakami, K1
Masaki, H1
Akiyama, M1
Ohishi, K1
Takahashi, A1
Nagatake, T1
Pagel, J1
Mohorn, M1
Kloetzer, KH1
Fleck, M1
Wendt, TG1
Matsuura, K1
Hirokawa, Y1
Matsuura, A1
Akagi, Y1
Ito, K1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective, Randomized, Controlled Phase Ⅱ Study of Preventively Use of Methylprednisolone After Split-course Chemoradiotherapy to Reduce the Risk of Radiation-induced Pulmonary Injury For Bulky Local Advanced None-small Cell Lung Cancer[NCT03661567]Phase 252 participants (Actual)Interventional2018-08-09Terminated (stopped due to slow enrollment)
Prophylactic Inhaled Steroids to Reduce Radiation Pneumonitis Frequency and Severity in Non-small Cell Lung Cancer Patients[NCT03803787]Phase 272 participants (Anticipated)Interventional2018-09-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for prednisolone and Radiation Pneumonitis

ArticleYear
Radiation induced lung injury: prediction, assessment and management.
    Asian Pacific journal of cancer prevention : APJCP, 2015, Volume: 16, Issue:7

    Topics: Aged; Alveolar Epithelial Cells; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents;

2015
Cryptogenic organizing pneumonia after radiotherapy for breast cancer.
    Breast cancer (Tokyo, Japan), 2005, Volume: 12, Issue:3

    Topics: Adrenal Cortex Hormones; Breast Neoplasms; Female; Humans; Mastectomy; Mastectomy, Segmental; Middle

2005

Trials

1 trial available for prednisolone and Radiation Pneumonitis

ArticleYear
[The inhalation versus systemic prevention of pneumonitis during thoracic irradiation].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1998, Volume: 174, Issue:1

    Topics: Administration, Inhalation; Administration, Oral; Anti-Bacterial Agents; Beclomethasone; Carcinoma,

1998

Other Studies

9 other studies available for prednisolone and Radiation Pneumonitis

ArticleYear
Relapsing polychondritis after treatment with PD-1 blockade.
    Investigational new drugs, 2022, Volume: 40, Issue:2

    Topics: Aged; Fluorodeoxyglucose F18; Humans; Male; Nivolumab; Polychondritis, Relapsing; Positron Emission

2022
Prevalence and Characteristics of Pneumonitis Following Irradiation of Breast Cancer.
    Anticancer research, 2019, Volume: 39, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Antineoplastic Agents; Antineoplastic Agen

2019
Radiation pneumonitis after definitive concurrent chemoradiotherapy with cisplatin/docetaxel for non-small cell lung cancer: Analysis of dose-volume parameters.
    Cancer medicine, 2020, Volume: 9, Issue:13

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols

2020
Inhalative steroids as an individual treatment in symptomatic lung cancer patients with radiation pneumonitis grade II after radiotherapy - a single-centre experience.
    Radiation oncology (London, England), 2016, Feb-02, Volume: 11

    Topics: Administration, Inhalation; Administration, Oral; Aged; Aged, 80 and over; Carcinoma, Non-Small-Cell

2016
Early onset recall pneumonitis during targeted therapy with sunitinib.
    BMC cancer, 2013, Jan-02, Volume: 13

    Topics: Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Glucocorticoids; Humans; Indoles; Kidney Neoplas

2013
Treatment of radiation pneumonitis with prednisolone.
    British journal of diseases of the chest, 1959, Volume: 53

    Topics: Humans; Pneumonia; Prednisolone; Psychotherapy; Radiation; Radiation Injuries; Radiation Pneumonitis

1959
Avascular necrosis of bilateral femoral head as a result of long-term steroid administration for radiation pneumonitis after tangential irradiation of the breast.
    International journal of clinical oncology, 2006, Volume: 11, Issue:6

    Topics: Axilla; Breast Neoplasms; Combined Modality Therapy; Female; Femur Head Necrosis; Glucocorticoids; H

2006
[Clinical study of radiation pneumonitis over 10 years].
    Nihon Kyobu Shikkan Gakkai zasshi, 1995, Volume: 33, Issue:4

    Topics: Aged; Aged, 80 and over; Female; Humans; Lung Neoplasms; Male; Middle Aged; Prednisolone; Radiation

1995
[Migratory pneumonitis similar to bronchiolitis obliterans organizing pneumonia after conservative treatment of breast cancer: a case report].
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1999, Volume: 59, Issue:8

    Topics: Anti-Inflammatory Agents; Breast Neoplasms; Cryptogenic Organizing Pneumonia; Female; Humans; Middle

1999