Page last updated: 2024-11-06

prednisolone and Psychotic Disorders

prednisolone has been researched along with Psychotic Disorders in 28 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Psychotic Disorders: Disorders in which there is a loss of ego boundaries or a gross impairment in reality testing with delusions or prominent hallucinations. (From DSM-IV, 1994)

Research Excerpts

ExcerptRelevanceReference
"In this double-blind, placebo-controlled clinical trial, patients with schizophrenia, schizoaffective disorder or psychosis NOS were randomized 1:1 to either prednisolone or placebo, in addition to their regular antipsychotic medication."9.41The effect of prednisolone on symptom severity in schizophrenia: A placebo-controlled, randomized controlled trial. ( Boudewijns, ZSRM; de Witte, LD; Gangadin, SS; Kahn, RS; Luykx, J; Nasib, LG; Rossum, IW; Somers, M; Sommer, IE; van Baal, C; Veen, N; Wilting, I, 2021)
"In this double-blind, placebo-controlled clinical trial, patients with schizophrenia, schizoaffective disorder or psychosis NOS were randomized 1:1 to either prednisolone or placebo, in addition to their regular antipsychotic medication."5.41The effect of prednisolone on symptom severity in schizophrenia: A placebo-controlled, randomized controlled trial. ( Boudewijns, ZSRM; de Witte, LD; Gangadin, SS; Kahn, RS; Luykx, J; Nasib, LG; Rossum, IW; Somers, M; Sommer, IE; van Baal, C; Veen, N; Wilting, I, 2021)
"Sydenham's chorea is the most frequently acquired movement disorder in childhood and is characterized by involuntary and abrupt movement patterns."2.46[Schizophreniform symptoms in Chorea Minor--case report and literature review]. ( Hahn, F; Häusler, M; Herpertz-Dahlmann, B; Holtkamp, K; Vloet, JA, 2010)
"Three days later, she had right sensorineural hearing loss (SNHL)."1.39[A case of steroid psychosis caused by treatment for acute sensorineural hearing loss]. ( Kohno, N; Masuda, M; Sato, Y, 2013)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199011 (39.29)18.7374
1990's2 (7.14)18.2507
2000's7 (25.00)29.6817
2010's6 (21.43)24.3611
2020's2 (7.14)2.80

Authors

AuthorsStudies
Nasib, LG2
Sommer, IE2
Winter-van Rossum, I1
de Vries, J1
Gangadin, SS2
Oomen, PP1
Judge, G1
Blom, RE1
Luykx, JJ1
van Beveren, NJM1
Veen, ND1
Kroken, RA1
Johnsen, EL1
Rossum, IW1
Boudewijns, ZSRM1
de Witte, LD1
Wilting, I1
Luykx, J1
Somers, M1
Veen, N1
van Baal, C1
Kahn, RS1
Sato, Y1
Masuda, M1
Kohno, N1
Marinelli, T1
Chen, L1
Kulkarni, J1
Vivek, AK1
Arun, AB1
Menon, V1
Kandasamy, P1
Vloet, JA1
Herpertz-Dahlmann, B1
Hahn, F1
Häusler, M1
Holtkamp, K1
Uzawa, A1
Mori, M1
Takahashi, Y1
Ogawa, Y1
Uchiyama, T1
Kuwabara, S1
Kendall, KM1
Thomas, RH1
Corkill, RG1
Robertson, NP1
HOEPKER, W1
HOFMANN, G1
SOLMS, W1
WALCHER, W1
SLAVICH, A1
TESI, L1
SEMENDIAEVA, ME1
BOGDANOVA, NV1
BOCK, HE1
LENOCH, F1
DOSTAL, C1
YANAGISAWA, Y1
KIENLE, G1
Mendhekar, DN1
Mehta, R1
Puri, V1
Mocellin, R1
Lubman, DI1
Lloyd, J1
Tomlinson, EB1
Velakoulis, D1
Krishna, K1
Singh, P1
Pradhan, AB1
Ishii, M1
Muramoto, Y1
Kosaka, H1
Ohshima, S1
Mima, T1
Katada, Y1
Hirohata, S1
Saeki, Y1
Hommet, C1
Mondon, K1
Huc, M1
Jeffredo, S1
Constans, T1
de Toffol, B1
Camus, V1
Cansu, D1
Kaşifoğlu, T1
Paşaoğlu, O1
Korkmaz, C1
Gardner-Medwin, JM1
Powell, RJ1
Johnson, H1
Bouman, W1
Pinner, G1
Onizuka, T1
Tsuji, H1
Nomiyama, K1
Fujishima, M1
Iida, M1
Nagasawa, K1
Nakashima, K1
Mukherji, N1
Pal, S1
Sen, R1
Mukherji, P1
Biswas, TK1
Dey, SC1
Warnecke, H1
Schueler, S1
Schliffka, J1
Hetzer, R1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Norwegian Prednisolone in Early Psychosis Study - NorPEPS. The Role of Immune-modulating Strategies in the Treatment of Psychosis[NCT03340909]Phase 212 participants (Actual)Interventional2018-02-02Terminated (stopped due to Stopped because of COVID 19 pandemic)
Prednisolone Addition for Patients With Recent-onset Psychotic Disorder: the Role of Immune-modulating Strategies in the Treatment of Psychosis[NCT02949232]Phase 442 participants (Actual)Interventional2014-07-31Terminated (stopped due to Difficulties with recruitment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for prednisolone and Psychotic Disorders

ArticleYear
[Schizophreniform symptoms in Chorea Minor--case report and literature review].
    Zeitschrift fur Kinder- und Jugendpsychiatrie und Psychotherapie, 2010, Volume: 38, Issue:3

    Topics: Anti-Inflammatory Agents; Antipsychotic Agents; Basal Ganglia; Child; Chorea; Corpus Striatum; Drug

2010
Psychiatric aspects of temporal arteritis: a case report and review of the literature.
    Journal of geriatric psychiatry and neurology, 1997, Volume: 10, Issue:4

    Topics: Aged; Biopsy; Blood Sedimentation; Cognition Disorders; Diagnosis, Differential; Female; Geriatric A

1997
[A case of lupoid hepatitis satisfying criteria for systemic lupus erythematosus associated with psychosis].
    Fukuoka igaku zasshi = Hukuoka acta medica, 2001, Volume: 92, Issue:7

    Topics: Adult; Antibodies, Antinuclear; Biomarkers; Female; Hepatitis, Autoimmune; Humans; Lupus Erythematos

2001

Trials

2 trials available for prednisolone and Psychotic Disorders

ArticleYear
Prednisolone versus placebo addition in the treatment of patients with recent-onset psychotic disorder: a trial design.
    Trials, 2020, Jun-08, Volume: 21, Issue:1

    Topics: Antipsychotic Agents; Clinical Trials, Phase IV as Topic; Drug Therapy, Combination; Humans; Multice

2020
The effect of prednisolone on symptom severity in schizophrenia: A placebo-controlled, randomized controlled trial.
    Schizophrenia research, 2021, Volume: 230

    Topics: Antipsychotic Agents; Double-Blind Method; Humans; Prednisolone; Psychotic Disorders; Schizophrenia;

2021

Other Studies

23 other studies available for prednisolone and Psychotic Disorders

ArticleYear
[A case of steroid psychosis caused by treatment for acute sensorineural hearing loss].
    Nihon Jibiinkoka Gakkai kaiho, 2013, Volume: 116, Issue:8

    Topics: Acute Disease; Adult; Female; Hearing Loss, Sensorineural; Humans; Prednisolone; Psychotic Disorders

2013
First episode psychosis in an adult patient with tuberous sclerosis.
    The Australian and New Zealand journal of psychiatry, 2016, Volume: 50, Issue:3

    Topics: Benzodiazepines; Female; Humans; Middle Aged; Olanzapine; Prednisolone; Psychotic Disorders; Tuberou

2016
Acute polymorphic psychosis as a presenting feature of Hashimoto's encephalopathy.
    Asian journal of psychiatry, 2016, Volume: 19

    Topics: Adult; Antipsychotic Agents; Encephalitis; Female; Glucocorticoids; Hashimoto Disease; Humans; Predn

2016
Anti-N-methyl D-aspartate-type glutamate receptor antibody-positive limbic encephalitis in a patient with multiple sclerosis.
    Clinical neurology and neurosurgery, 2012, Volume: 114, Issue:4

    Topics: Adult; Anti-Inflammatory Agents; Autoantibodies; Brain; Cognition Disorders; Female; Humans; Limbic

2012
A neurological presentation of intravascular B-cell lymphoma.
    BMJ case reports, 2012, Aug-02, Volume: 2012

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Early Detection of Cancer; Humans;

2012
[Dexamethasone psychosis].
    Die Medizinische Welt, 1961, Jun-03, Volume: 22

    Topics: Dexamethasone; Humans; Mental Disorders; Prednisolone; Psychotic Disorders

1961
[Psychiatric complications during prednisolone therapy].
    Wiener klinische Wochenschrift, 1960, Jun-24, Volume: 72

    Topics: Humans; Mental Disorders; Prednisolone; Psychotic Disorders

1960
[Neurologic-psychiatric problems of extended 1st aid].
    Wiener medizinische Wochenschrift (1946), 1963, Jan-26, Volume: 113

    Topics: Cerebrovascular Disorders; Chlorpromazine; Epilepsy; First Aid; Humans; Mental Disorders; Meperidine

1963
[ON THE USE OF PREDNISOLONE AND CHLORPROMAZINE IN THE THERAPY OF DELIRIUM TREMENS].
    Rivista sperimentale di freniatria e medicina legale delle alienazioni mentali, 1963, Jun-30, Volume: 87

    Topics: Alcohol Withdrawal Delirium; Chlorpromazine; Humans; Mental Disorders; Prednisolone; Psychoses, Alco

1963
[NEURO-PSYCHIC CHANGES IN HORMONE THERAPY OF BOTKIN'S DISEASE].
    Sovetskaia meditsina, 1963, Volume: 27

    Topics: Adrenocorticotropic Hormone; Communicable Diseases; Cortisone; Dexamethasone; Hepatitis A; Neurologi

1963
[FUNDAMENTALS AND LIMITATIONS OF ACTH AND CORTISONE TREATMENT].
    Deutsche Zeitschrift fur Nervenheilkunde, 1963, Oct-14, Volume: 185

    Topics: Adrenocorticotropic Hormone; Arteritis; Cortisone; Dexamethasone; Hydrocortisone; Methylprednisolone

1963
[MENTAL DISORDERS FOLLOWING STEROID HORMONE THERAPY WITH SPECIAL REFERENCE TO SYSTEMIC LUPUS ERYTHEMATOSUS].
    Ceskoslovenska psychiatrie, 1964, Volume: 60

    Topics: Adrenocorticotropic Hormone; Central Nervous System Diseases; Collagen Diseases; Dexamethasone; Epil

1964
[THE INFLUENCE OF ASCORBIC ACID ON ADRENOCORTICAL FUNCTION AND ADRENOCORTICAL HORMONE].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1963, Apr-10, Volume: 52

    Topics: 17-Ketosteroids; Addison Disease; Adrenal Cortex Hormones; Adrenal Glands; Adrenal Insufficiency; Ad

1963
[ANALEPTIC TREATMENT OF THE ALCOHOLIC DELIRIUM].
    Der Nervenarzt, 1964, Volume: 35

    Topics: Ascorbic Acid; Benzaldehydes; Central Nervous System Stimulants; Delirium; Folic Acid; Fructose; Hum

1964
Successful steroid therapy in multiple sclerosis presented as acute psychosis.
    The Journal of the Association of Physicians of India, 2004, Volume: 52

    Topics: Acute Disease; Adult; Female; Glucocorticoids; Humans; Multiple Sclerosis; Prednisolone; Psychotic D

2004
Reversible dementia with psychosis: Hashimoto's encephalopathy.
    Psychiatry and clinical neurosciences, 2006, Volume: 60, Issue:6

    Topics: Aged; Anti-Inflammatory Agents; Autoantibodies; Brain Damage, Chronic; Delusions; Dementia; Female;

2006
Atypical presentations of Sheehan's syndrome.
    The Journal of the Association of Physicians of India, 2006, Volume: 54

    Topics: Acute Disease; Adult; Antipsychotic Agents; Estrogen Replacement Therapy; Female; Humans; Hypopituit

2006
A serological switching from anti-dsDNA to anti-Sm antibodies coincided with severe clinical manifestations of systemic lupus erythematosus (hemophagocytosis, profundus and psychosis).
    Lupus, 2007, Volume: 16, Issue:1

    Topics: Administration, Oral; Antibodies, Antinuclear; Antibody Specificity; Autoantibodies; Autoantigens; C

2007
Atypical neuropsychiatric symptoms revealing Hashimoto's encephalopathy.
    Journal of the American Geriatrics Society, 2007, Volume: 55, Issue:7

    Topics: Aged; Brain Diseases; Diagnosis, Differential; Female; Follow-Up Studies; Glucocorticoids; Hashimoto

2007
Autoerythrocyte sensitization syndrome (Gardner-Diamond syndrome) associated with cutaneous vasculitis.
    Joint bone spine, 2008, Volume: 75, Issue:6

    Topics: Antipsychotic Agents; Autoantibodies; Autoimmune Diseases; Colchicine; Drug Therapy, Combination; Ec

2008
One patient, two unusual conditions and three basic lessons.
    Annals of the rheumatic diseases, 1996, Volume: 55, Issue:6

    Topics: Amphotericin B; Connective Tissue Diseases; Drug Therapy, Combination; Female; Humans; Knee Prosthes

1996
Systemic lupus erythematosus in a young male.
    Journal of the Indian Medical Association, 1989, Volume: 87, Issue:9

    Topics: Adult; Humans; India; Lupus Erythematosus, Systemic; Male; Neurocognitive Disorders; Prednisolone; P

1989
Neurologic complications after heart transplantation: the influence of immunosuppression.
    Transplantation proceedings, 1987, Volume: 19, Issue:1 Pt 3

    Topics: Antilymphocyte Serum; Azathioprine; Cyclosporins; Heart Transplantation; Humans; Immunosuppression T

1987