prednisolone has been researched along with Proctitis in 23 studies
Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.
Proctitis: INFLAMMATION of the MUCOUS MEMBRANE of the RECTUM, the distal end of the large intestine (INTESTINE, LARGE).
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a double-blind randomized clinical trial 18 patients with exacerbations of distal ulcerative colitis were treated for 4 weeks with enemas containing either prednisolone 21-phosphate 30 mg (PP) or beclomethasone dipropionate 1 mg (BDP) a surface-active corticosteroid." | 9.06 | Comparison of beclomethasone dipropionate and prednisolone 21-phosphate enemas in the treatment of ulcerative proctitis. ( Dekker, W; Endert, E; Schipper, ME; Tytgat, GN; van den Brandt-Gradel, V; van der Heide, H; Wiltink, EH, 1988) |
| "The local release of human neutrophil lipocalin, considered to be highly specific for neutrophil granulocyte activation, and interleukin-8 and tumor necrosis factor-alpha were studied in 11 patients with distal ulcerative colitis and proctitis before and during treatment with steroid enemas." | 7.71 | Local release of human neutrophil lipocalin (HNL), IL-8, and TNF-alpha is decreased as response to topical prednisolone treatment in distal ulcerative colitis and proctitis. ( Carlson, M; Lööf, L; Raab, Y; Sangfelt, P; Thörn, M; Xu, S, 2002) |
| "A double blind trial of prednisolone suppositories in out-patients with idiopathic proctitis is reported." | 7.64 | A double blind controlled trial of prednisolone-21-phosphate suppositories in the treatment of idiopathic proctitis. ( BARON, JH; CONNELL, AM; JONES, FA; LENNARD-JONES, JE, 1962) |
| "It is concluded that in the topical treatment of ulcerative colitis, BDP may be preferable to PP because it exerts a promising anti-inflammatory action without affecting adrenocortical function." | 6.66 | Comparison of beclomethasone dipropionate (2 and 3 mg) and prednisolone sodium phosphate enemas (30 mg) in the treatment of ulcerative proctitis. An adrenocortical approach. ( Endert, E; Houthoff, HJ; Mulder, CJ; Tytgat, GN; van der Heide, H; Wiersinga, W; Wiltink, EH, 1989) |
| "Forty mg has been shown to be the optimal daily dosage of prednisone for outpatients requiring oral steroids for active proctocolitis." | 6.64 | A comparison of oral prednisolone given as single or multiple daily doses for active proctocolitis. ( Bown, RL; Lennard-Jones, JE; Powell-Tuck, J, 1978) |
| "In a double-blind randomized clinical trial 18 patients with exacerbations of distal ulcerative colitis were treated for 4 weeks with enemas containing either prednisolone 21-phosphate 30 mg (PP) or beclomethasone dipropionate 1 mg (BDP) a surface-active corticosteroid." | 5.06 | Comparison of beclomethasone dipropionate and prednisolone 21-phosphate enemas in the treatment of ulcerative proctitis. ( Dekker, W; Endert, E; Schipper, ME; Tytgat, GN; van den Brandt-Gradel, V; van der Heide, H; Wiltink, EH, 1988) |
| "The local release of human neutrophil lipocalin, considered to be highly specific for neutrophil granulocyte activation, and interleukin-8 and tumor necrosis factor-alpha were studied in 11 patients with distal ulcerative colitis and proctitis before and during treatment with steroid enemas." | 3.71 | Local release of human neutrophil lipocalin (HNL), IL-8, and TNF-alpha is decreased as response to topical prednisolone treatment in distal ulcerative colitis and proctitis. ( Carlson, M; Lööf, L; Raab, Y; Sangfelt, P; Thörn, M; Xu, S, 2002) |
| "Nine patients suffering from active ulcerative proctitis underwent four weeks of therapy with prednisolone metasulphobenzoate foam enemas." | 3.69 | Prednisolone metasulphobenzoate foam retention enemas suppress the hypothalamo-pituitary-adrenal axis. ( Gray, RS; Luman, W; Palmer, KR; Pendek, R, 1994) |
| "A double blind trial of prednisolone suppositories in out-patients with idiopathic proctitis is reported." | 3.64 | A double blind controlled trial of prednisolone-21-phosphate suppositories in the treatment of idiopathic proctitis. ( BARON, JH; CONNELL, AM; JONES, FA; LENNARD-JONES, JE, 1962) |
| "It is concluded that in the topical treatment of ulcerative colitis, BDP may be preferable to PP because it exerts a promising anti-inflammatory action without affecting adrenocortical function." | 2.66 | Comparison of beclomethasone dipropionate (2 and 3 mg) and prednisolone sodium phosphate enemas (30 mg) in the treatment of ulcerative proctitis. An adrenocortical approach. ( Endert, E; Houthoff, HJ; Mulder, CJ; Tytgat, GN; van der Heide, H; Wiersinga, W; Wiltink, EH, 1989) |
| "Forty mg has been shown to be the optimal daily dosage of prednisone for outpatients requiring oral steroids for active proctocolitis." | 2.64 | A comparison of oral prednisolone given as single or multiple daily doses for active proctocolitis. ( Bown, RL; Lennard-Jones, JE; Powell-Tuck, J, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (69.57) | 18.7374 |
| 1990's | 3 (13.04) | 18.2507 |
| 2000's | 3 (13.04) | 29.6817 |
| 2010's | 1 (4.35) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gecse, KB | 1 |
| Lakatos, PL | 1 |
| Sangfelt, P | 2 |
| Carlson, M | 2 |
| Thörn, M | 2 |
| Xu, S | 1 |
| Lööf, L | 2 |
| Raab, Y | 2 |
| MARINUS, C | 1 |
| TRUELOVE, SC | 1 |
| ROSA, JV | 1 |
| LENNARD-JONES, JE | 4 |
| BARON, JH | 2 |
| CONNELL, AM | 2 |
| JONES, FA | 3 |
| FONTANA DONATELLI, G | 1 |
| D AMBROSIO, F | 1 |
| LORETAN, RM | 1 |
| RIIS, P | 1 |
| SOGAARD-ANDERSEN, T | 1 |
| ANTHONISEN, P | 1 |
| MISIEWICZ, JJ | 2 |
| PARIS, J | 1 |
| Cantisani, V | 1 |
| Mortele, KJ | 1 |
| Viscomi, SG | 1 |
| Glickman, J | 1 |
| Silverman, SG | 1 |
| Ros, PR | 1 |
| Dwarakanath, AD | 1 |
| Nash, J | 1 |
| Rhodes, JM | 1 |
| Luman, W | 1 |
| Gray, RS | 1 |
| Pendek, R | 1 |
| Palmer, KR | 1 |
| Declerck, D | 1 |
| Wallaert, B | 1 |
| Demarcq-Delerue, G | 1 |
| Tonnel, AB | 1 |
| Powell-Tuck, J | 1 |
| Bown, RL | 1 |
| Mulder, CJ | 1 |
| Endert, E | 2 |
| van der Heide, H | 2 |
| Houthoff, HJ | 1 |
| Wiersinga, W | 1 |
| Wiltink, EH | 2 |
| Tytgat, GN | 2 |
| van den Brandt-Gradel, V | 1 |
| Schipper, ME | 1 |
| Dekker, W | 1 |
| Kaufmann, W | 1 |
| Brostoff, J | 1 |
| Walker, JG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Decisional Influences and IBD Patients' Medication Use[NCT00968721] | 55 participants (Actual) | Observational | 2010-06-30 | Terminated (stopped due to lack of support) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for prednisolone and Proctitis
| Article | Year |
|---|---|
Ulcerative proctitis: an update on the pharmacotherapy and management.
Topics: Anti-Inflammatory Agents; Colitis, Ulcerative; Disease Management; Humans; Mesalamine; Prednisolone; | 2014 |
4 trials available for prednisolone and Proctitis
| Article | Year |
|---|---|
A comparison of oral prednisolone given as single or multiple daily doses for active proctocolitis.
Topics: Administration, Oral; Adult; Clinical Trials as Topic; Colitis; Drug Evaluation; Female; Humans; Mal | 1978 |
Comparison of beclomethasone dipropionate (2 and 3 mg) and prednisolone sodium phosphate enemas (30 mg) in the treatment of ulcerative proctitis. An adrenocortical approach.
Topics: Adult; Aged; Beclomethasone; Colitis, Ulcerative; Enema; Female; Humans; Hydrocortisone; Male; Middl | 1989 |
Comparison of beclomethasone dipropionate and prednisolone 21-phosphate enemas in the treatment of ulcerative proctitis.
Topics: Adult; Beclomethasone; Clinical Trials as Topic; Cosyntropin; Double-Blind Method; Enema; Female; Hu | 1988 |
Betamethasone 17-valerate and prednisolone 21-phosphate retention enemata in proctocolitis. A multicentre trial.
Topics: Adolescent; Adrenal Glands; Adult; Aged; Betamethasone; Colitis, Ulcerative; Depression, Chemical; E | 1971 |
18 other studies available for prednisolone and Proctitis
| Article | Year |
|---|---|
Local release of human neutrophil lipocalin (HNL), IL-8, and TNF-alpha is decreased as response to topical prednisolone treatment in distal ulcerative colitis and proctitis.
Topics: Acute-Phase Proteins; Anti-Inflammatory Agents; Carrier Proteins; Colitis, Ulcerative; Enema; Humans | 2002 |
[A case of ulcero-hemorrhagic rectitis treated with prednisolone suppositories].
Topics: Disease; Enteritis; Gastrointestinal Hemorrhage; Prednisolone; Proctitis; Rectal Diseases; Rectum; S | 1958 |
Suppository treatment of haemorrhagic proctitis.
Topics: Disease; Hydrocortisone; Prednisolone; Proctitis; Rectal Diseases; Rectum; Suppositories; Vascular D | 1959 |
[Treatment of lymphogranulomatous stenosing rectitis with prednisolone].
Topics: Lymphogranuloma Venereum; Prednisolone; Proctitis; Rectum | 1960 |
A double blind controlled trial of prednisolone-21-phosphate suppositories in the treatment of idiopathic proctitis.
Topics: Chronic Disease; Colitis, Ulcerative; Double-Blind Method; Humans; Phosphates; Prednisolone; Proctit | 1962 |
[CLINICAL CONSIDERATIONS ON PROCTITIS CAUSED BY IRRADIATION AND ON THE THERAPEUTIC POSSIBILITIES OF A NEW CORTICOID PREPARATION WITH LOCAL ACTION].
Topics: Adrenal Cortex Hormones; Biomedical Research; Carcinoma; Carcinoma, Squamous Cell; Female; Humans; N | 1963 |
[ANORECTAL CONGESTIVE STATES AND THEIR TREATMENT BY Z2020].
Topics: Cardiovascular Agents; Clioquinol; Fissure in Ano; Flavonoids; Hemorrhoids; Humans; Pessaries; Predn | 1963 |
[TREATMENT OF NONSPECIFIC HEMORRHAGIC PROCTOCOLITIS WITH PHENYLBUTAZONE AND PREDNISOLONE SUPPOSITORIES. LIGHT CASES STUDIED WITH THE DOUBLE-BLIND TECHNIC].
Topics: Biomedical Research; Colitis; Colitis, Ulcerative; Denmark; Double-Blind Method; Gastrointestinal He | 1964 |
COMPARISON OF ORAL AND RECTAL STEROIDS IN THE TREATMENT OF PROCTOCOLITIS.
Topics: Administration, Topical; Barium Sulfate; Colitis; Gastrointestinal Hemorrhage; Hemorrhage; Humans; P | 1964 |
[ESSENTIAL HEMORRHAGIC RECTITIS].
Topics: Colitis; Colitis, Ulcerative; Diagnosis, Differential; Gastrointestinal Hemorrhage; Humans; Hydrocor | 1964 |
COMPARISON OF ACETARSOL AND PREDNISOLONE-21-PHOSPHATE SUPPOSITORIES IN THE TREATMENT OF IDIOPATHIC PROCTITIS.
Topics: Arsenicals; Colitis, Ulcerative; Drug Therapy; Humans; Phosphates; Prednisolone; Proctitis; Supposit | 1965 |
Rectal inflammation as first manifestation of graft-vs-host disease: radiologic-pathologic findings.
Topics: Adult; Biopsy, Needle; Bone Marrow Transplantation; Cyclosporine; Drug Therapy, Combination; Female; | 2003 |
'Conversion' from ulcerative colitis to Crohn's disease associated with corticosteroid treatment.
Topics: Adult; Colitis, Ulcerative; Colon; Crohn Disease; Humans; Immunocompromised Host; Long-Term Care; Ma | 1994 |
Prednisolone metasulphobenzoate foam retention enemas suppress the hypothalamo-pituitary-adrenal axis.
Topics: Administration, Rectal; Adult; Aged; Blood Glucose; Cortodoxone; Enema; Female; Homeostasis; Humans; | 1994 |
[Iatrogenic diffuse interstitial pneumonia linked to 5-aminosalicylate].
Topics: Aminosalicylic Acids; Colitis; Drug Therapy, Combination; Female; Gastrointestinal Hemorrhage; Human | 1994 |
Neutrophil and eosinophil granule proteins as markers of response to local prednisolone treatment in distal ulcerative colitis and proctitis.
Topics: Administration, Topical; Adult; Aged; Anti-Inflammatory Agents; Blood Proteins; Colitis, Ulcerative; | 2001 |
[Rectitis (rectosigmoiditis, rare rectocolitis hemorrhagica) in ambulant gastroenterologic metropolitan practice, 37 cases in about 10,000 first admissions].
Topics: Adult; Aged; Colitis; Colon, Sigmoid; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; | 1967 |
Leucocyte migration inhibition with Kveim antigen in Crohn's disease.
Topics: Aged; Antigens; Cell Migration Inhibition; Colitis; Crohn Disease; Female; Humans; Leukocytes; Lymph | 1971 |