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prednisolone and Primary Graft Dysfunction

prednisolone has been researched along with Primary Graft Dysfunction in 1 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Primary Graft Dysfunction: A form of ischemia-reperfusion injury occurring in the early period following transplantation. Significant pathophysiological changes in MITOCHONDRIA are the main cause of the dysfunction. It is most often seen in the transplanted lung, liver, or kidney and can lead to GRAFT REJECTION.

Research Excerpts

ExcerptRelevanceReference
"Prednisolone was either added to the perfusion solution for lung preservation or omitted and rats were followed for 48 hours after LTX."1.39Prednisolone as preservation additive prevents from ischemia reperfusion injury in a rat model of orthotopic lung transplantation. ( Holfeld, J; Mutlak, H; Ockelmann, PA; Paulus, P; Reissig, C; Scheller, B; Stay, D; Tacke, S; Urbschat, A; Zacharowski, K, 2013)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Paulus, P1
Holfeld, J1
Urbschat, A1
Mutlak, H1
Ockelmann, PA1
Tacke, S1
Zacharowski, K1
Reissig, C1
Stay, D1
Scheller, B1

Other Studies

1 other study available for prednisolone and Primary Graft Dysfunction

ArticleYear
Prednisolone as preservation additive prevents from ischemia reperfusion injury in a rat model of orthotopic lung transplantation.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Cell Transdifferentiation; Cellular Microenvironment; Gene Expres

2013