Compounds > prednisolone
Page last updated: 2024-11-06

prednisolone and Pericarditis, Tuberculous

prednisolone has been researched along with Pericarditis, Tuberculous in 30 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Pericarditis, Tuberculous: INFLAMMATION of the sac surrounding the heart (PERICARDIUM) due to MYCOBACTERIUM TUBERCULOSIS infection. Pericarditis can lead to swelling (PERICARDIAL EFFUSION), compression of the heart (CARDIAC TAMPONADE), and preventing normal beating of the heart.

Research Excerpts

ExcerptRelevanceReference
"In Transkei, 143 patients with active tuberculous constrictive pericarditis without significant pericardial effusion all received the same daily 6-month antituberculosis regimen of streptomycin, isoniazid, rifampicin, and pyrazinamide for 14 weeks followed by isoniazid and rifampicin."9.06Controlled trial of prednisolone as adjuvant in treatment of tuberculous constrictive pericarditis in Transkei. ( Fox, W; Gibson, DG; Girling, DJ; Kakaza, HH; Nunn, AJ; Strang, JI, 1987)
" Two randomized trials showed benefits at two years for prednisolone in patients with constrictive pericarditis, and open drainage plus prednisolone in patients with pericardial effusion."5.11Management of tuberculous constrictive pericarditis and tuberculous pericardial effusion in Transkei: results at 10 years follow-up. ( Casbard, A; Gibson, DG; Girling, DJ; Johnson, DA; Nunn, AJ; Strang, JI, 2004)
"In Transkei, 143 patients with active tuberculous constrictive pericarditis without significant pericardial effusion all received the same daily 6-month antituberculosis regimen of streptomycin, isoniazid, rifampicin, and pyrazinamide for 14 weeks followed by isoniazid and rifampicin."5.06Controlled trial of prednisolone as adjuvant in treatment of tuberculous constrictive pericarditis in Transkei. ( Fox, W; Gibson, DG; Girling, DJ; Kakaza, HH; Nunn, AJ; Strang, JI, 1987)
"A 31-year-old patient with a massive effusion in the pericardial cavity, pleural lesion, arthritis of the left knee joint, whose results of the pericardial effusion and sputum were not diagnosed, tuberculosis was detected only with thoracoscopic biopsy of the lung and intrathoracic lymph nodes; the treatment via prednisolone and subtotal pericardectomy was performed."3.88Exudative-constrictive tuberculous pericarditis in combination with arthritis in cardiologist practice: thoracoscopic biopsy as a diagnosis and treatment method. ( Alijeva, IN; Blagova, OV; Kaburova, AN; Kogan, EA; Nedostup, AV; Parshin, VD; Senchihin, PV, 2018)
"In patients with tuberculous pericarditis, neither prednisolone nor M."2.79Prednisolone and Mycobacterium indicus pranii in tuberculous pericarditis. ( Aje, A; Ansa, V; Awotedu, AA; Barasa, AF; Bosch, J; Brown, B; Chitsa Banda, A; Damasceno, A; Danbauchi, S; Essop, MR; Francis, V; Gumedze, F; Hakim, J; Joldersma, L; Jung, H; Kirenga, B; Magula, NP; Manga, P; Matenga, J; Mayosi, BM; Mntla, P; Mondo, C; Naidoo, DP; Ntsekhe, M; Ogah, O; Ojji, D; Olunuga, T; Pandie, S; Peters, F; Pogue, J; Russell, JB; Sani, MU; Smieja, M; Thabane, L; Thomas, B; Thomas, KM; Tsitsi, JM; Yusuf, S, 2014)
"Adjunctive prednisolone for effusive tuberculous pericarditis produced a pronounced reduction in mortality."2.69Double blind randomised placebo controlled trial of adjunctive prednisolone in the treatment of effusive tuberculous pericarditis in HIV seropositive patients. ( Hakim, JG; Malin, A; Mushangi, E; Robertson, V; Siziya, S; Ternouth, I, 2000)
"Tuberculous pericarditis is a less common but more lethal form of tuberculosis and has a similar inflammatory process in the pericardium."1.91A description of the elevation of pericardial cortisol: cortisone ratio in patients with tuberculous pericarditis. ( Raubenheimer, P; Ross, I; Shenje, JT; Wiesner, L, 2023)
"Prednisolone (20-30 mg/d) was used in addition to antituberculous chemotherapy in 11 of the 17 patients with effusive pericarditis."1.30Constrictive pericarditis in patients with tuberculous pericarditis. ( Chen, KY; Kao, HL; Liaw, YS; Luh, KT; Yang, PC, 1999)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19906 (20.00)18.7374
1990's3 (10.00)18.2507
2000's6 (20.00)29.6817
2010's14 (46.67)24.3611
2020's1 (3.33)2.80

Authors

AuthorsStudies
Shenje, JT1
Raubenheimer, P1
Wiesner, L1
Ross, I1
Iddrisu, AK1
Gumedze, F3
Blagova, OV1
Alijeva, IN1
Nedostup, AV1
Kaburova, AN1
Senchihin, PV1
Parshin, VD1
Kogan, EA1
Chaisson, RE2
Post, WS2
Mayosi, BM4
Ntsekhe, M4
Bosch, J2
Pandie, S2
Jung, H2
Pogue, J2
Thabane, L2
Smieja, M3
Francis, V2
Joldersma, L1
Thomas, KM2
Thomas, B2
Awotedu, AA2
Magula, NP2
Naidoo, DP2
Damasceno, A2
Chitsa Banda, A1
Brown, B2
Manga, P2
Kirenga, B2
Mondo, C2
Mntla, P2
Tsitsi, JM2
Peters, F2
Essop, MR2
Russell, JB2
Hakim, J2
Matenga, J2
Barasa, AF2
Sani, MU2
Olunuga, T2
Ogah, O2
Ansa, V2
Aje, A2
Danbauchi, S2
Ojji, D2
Yusuf, S2
Kalsdorf, B1
Nandi, D1
Meybeck, A1
Pasquet, A1
Senneville, E1
Chhabra, L1
Spodick, DH1
Wiysonge, CS1
Desai, NM1
Khamar, BM1
Oo, YH1
Syn, WK1
Heller, T1
Lessells, RJ1
Wallrauch, C1
Brunetti, E1
Badri, M1
Banda, AC1
Mutyaba, A1
Ntuli, P1
Ntyintyane, L1
Ramjee, R1
Mijinyawa, MS1
Adebiyi, A1
Yildiz, M1
Erdogan, O1
Aktoz, M1
Gul, C1
Ozbay, G1
Wiysonge, C1
Volmink, JA1
Commerford, PJ1
PINTO, IJ1
KAMATH, PG1
Strang, JI4
Nunn, AJ3
Johnson, DA1
Casbard, A1
Gibson, DG3
Girling, DJ3
Bhan, GL1
Hathirat, S1
Vathesatogkit, P1
Charoenpan, P1
Wijesundere, A1
Siribaddana, SH1
Chen, KY1
Liaw, YS1
Kao, HL1
Yang, PC1
Luh, KT1
Wragg, A1
Hakim, JG1
Ternouth, I1
Mushangi, E1
Siziya, S1
Robertson, V1
Malin, A1
van Marle, W1
Woods, KL1
Beeley, L1
Yabe, T1
Doi, Y1
Takada, J1
Akisawa, M1
Nishinaga, M1
Mitsutani, K1
Yamada, M1
Odawara, H1
Yonesawa, M1
Ozawa, T1
Kakaza, HH2
Fox, W2
Allen, BW1
Mitchison, DA1
Evans, DJ1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Double Blind Placebo Controlled Trial of Adjunctive Dexamethasone for the Treatment of HIV-infected Adults With Tuberculous Meningitis[NCT03092817]Phase 3520 participants (Actual)Interventional2017-05-25Active, not recruiting
A Trial of Adjunctive Prednisolone and Mycobacterium w Immunotherapy in Tuberculous Pericarditis[NCT00810849]Phase 31,400 participants (Actual)Interventional2008-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for prednisolone and Pericarditis, Tuberculous

ArticleYear
Adjuvant corticosteroids for tuberculous pericarditis: promising, but not proven.
    QJM : monthly journal of the Association of Physicians, 2003, Volume: 96, Issue:8

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antitubercular Agents; Drug Therapy, Combination;

2003

Trials

6 trials available for prednisolone and Pericarditis, Tuberculous

ArticleYear
Prednisolone and Mycobacterium indicus pranii in tuberculous pericarditis.
    The New England journal of medicine, 2014, Sep-18, Volume: 371, Issue:12

    Topics: Adult; Cardiac Tamponade; Combined Modality Therapy; Female; Glucocorticoids; HIV Infections; Humans

2014
Prednisolone and Mycobacterium indicus pranii in tuberculous pericarditis.
    The New England journal of medicine, 2014, Sep-18, Volume: 371, Issue:12

    Topics: Adult; Cardiac Tamponade; Combined Modality Therapy; Female; Glucocorticoids; HIV Infections; Humans

2014
Prednisolone and Mycobacterium indicus pranii in tuberculous pericarditis.
    The New England journal of medicine, 2014, Sep-18, Volume: 371, Issue:12

    Topics: Adult; Cardiac Tamponade; Combined Modality Therapy; Female; Glucocorticoids; HIV Infections; Humans

2014
Prednisolone and Mycobacterium indicus pranii in tuberculous pericarditis.
    The New England journal of medicine, 2014, Sep-18, Volume: 371, Issue:12

    Topics: Adult; Cardiac Tamponade; Combined Modality Therapy; Female; Glucocorticoids; HIV Infections; Humans

2014
Rationale and design of the Investigation of the Management of Pericarditis (IMPI) trial: a 2 × 2 factorial randomized double-blind multicenter trial of adjunctive prednisolone and Mycobacterium w immunotherapy in tuberculous pericarditis.
    American heart journal, 2013, Volume: 165, Issue:2

    Topics: Adrenal Cortex Hormones; Aged; Antitubercular Agents; Bacterial Vaccines; Double-Blind Method; Femal

2013
Management of tuberculous constrictive pericarditis and tuberculous pericardial effusion in Transkei: results at 10 years follow-up.
    QJM : monthly journal of the Association of Physicians, 2004, Volume: 97, Issue:8

    Topics: Adolescent; Antitubercular Agents; Child; Child, Preschool; Drainage; Female; Follow-Up Studies; Hum

2004
Double blind randomised placebo controlled trial of adjunctive prednisolone in the treatment of effusive tuberculous pericarditis in HIV seropositive patients.
    Heart (British Cardiac Society), 2000, Volume: 84, Issue:2

    Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Anti-Inflammatory Agents; Antitubercular A

2000
Controlled trial of prednisolone as adjuvant in treatment of tuberculous constrictive pericarditis in Transkei.
    Lancet (London, England), 1987, Dec-19, Volume: 2, Issue:8573

    Topics: Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Female; F

1987
Controlled clinical trial of complete open surgical drainage and of prednisolone in treatment of tuberculous pericardial effusion in Transkei.
    Lancet (London, England), 1988, Oct-01, Volume: 2, Issue:8614

    Topics: Adolescent; Adult; Africa, Southern; Antitubercular Agents; Child; Child, Preschool; Clinical Trials

1988

Other Studies

23 other studies available for prednisolone and Pericarditis, Tuberculous

ArticleYear
A description of the elevation of pericardial cortisol: cortisone ratio in patients with tuberculous pericarditis.
    Frontiers in endocrinology, 2023, Volume: 14

    Topics: Cortisone; Cytokines; Humans; Hydrocortisone; Pericarditis, Tuberculous; Pericardium; Prednisolone

2023
An application of a pattern-mixture model with multiple imputation for the analysis of longitudinal trials with protocol deviations.
    BMC medical research methodology, 2019, 01-09, Volume: 19, Issue:1

    Topics: Anti-Retroviral Agents; CD4 Lymphocyte Count; Data Accuracy; Data Interpretation, Statistical; Gluco

2019
Exudative-constrictive tuberculous pericarditis in combination with arthritis in cardiologist practice: thoracoscopic biopsy as a diagnosis and treatment method.
    Terapevticheskii arkhiv, 2018, Sep-20, Volume: 90, Issue:9

    Topics: Adult; Aged; Antitubercular Agents; Arthritis; Biopsy; Female; Glucocorticoids; Humans; Lung; Lymph

2018
Immunotherapy for tuberculous pericarditis.
    The New England journal of medicine, 2014, Sep-18, Volume: 371, Issue:12

    Topics: Female; Glucocorticoids; Humans; Immunotherapy; Male; Mycobacterium; Pericarditis, Tuberculous; Pred

2014
[Treating tuberculous pericarditis: prednisolone or mycobacteria therapy? - only prednisolone provides therapeutic gain].
    Deutsche medizinische Wochenschrift (1946), 2014, Volume: 139, Issue:48

    Topics: Female; Glucocorticoids; Humans; Immunotherapy; Male; Mycobacterium; Pericarditis, Tuberculous; Pred

2014
Immunotherapy for tuberculous pericarditis.
    The New England journal of medicine, 2014, 12-25, Volume: 371, Issue:26

    Topics: Female; Glucocorticoids; Humans; Immunotherapy; Male; Mycobacterium; Pericarditis, Tuberculous; Pred

2014
Immunotherapy for tuberculous pericarditis.
    The New England journal of medicine, 2014, 12-25, Volume: 371, Issue:26

    Topics: Female; Glucocorticoids; Humans; Immunotherapy; Male; Mycobacterium; Pericarditis, Tuberculous; Pred

2014
Immunotherapy for tuberculous pericarditis.
    The New England journal of medicine, 2014, 12-25, Volume: 371, Issue:26

    Topics: Female; Glucocorticoids; Humans; Immunotherapy; Male; Mycobacterium; Pericarditis, Tuberculous; Pred

2014
Immunotherapy for tuberculous pericarditis.
    The New England journal of medicine, 2014, 12-25, Volume: 371, Issue:26

    Topics: Female; Glucocorticoids; Humans; Immunotherapy; Male; Mycobacterium; Pericarditis, Tuberculous; Pred

2014
Immunotherapy for tuberculous pericarditis.
    The New England journal of medicine, 2014, 12-25, Volume: 371, Issue:26

    Topics: Female; Glucocorticoids; Humans; Immunotherapy; Male; Mycobacterium; Pericarditis, Tuberculous; Pred

2014
Immunotherapy for tuberculous pericarditis.
    The New England journal of medicine, 2014, 12-25, Volume: 371, Issue:26

    Topics: Female; Glucocorticoids; Humans; Immunotherapy; Male; Mycobacterium; Pericarditis, Tuberculous; Pred

2014
Immunotherapy for tuberculous pericarditis.
    The New England journal of medicine, 2014, 12-25, Volume: 371, Issue:26

    Topics: Female; Glucocorticoids; Humans; Immunotherapy; Male; Mycobacterium; Pericarditis, Tuberculous; Pred

2014
Persistent pyrexia post-liver transplantation: a unique case of pericardial tuberculosis.
    European journal of internal medicine, 2008, Volume: 19, Issue:8

    Topics: Antitubercular Agents; Drug Therapy, Combination; Female; Fever; Glucocorticoids; Humans; Immunocomp

2008
Tuberculosis pericarditis with cardiac tamponade: management in the resource-limited setting.
    The American journal of tropical medicine and hygiene, 2010, Volume: 83, Issue:6

    Topics: Adult; Anti-Inflammatory Agents; Antitubercular Agents; Cardiac Tamponade; HIV Infections; Humans; M

2010
Management of a patient with active rheumatoid arthritis and suspected tuberculosis causing effusive-constrictive pericarditis.
    International journal of cardiology, 2003, Volume: 89, Issue:1

    Topics: Antitubercular Agents; Arthritis, Rheumatoid; Female; Humans; Middle Aged; Pericardial Effusion; Per

2003
Corticosteroids in acute tuberculous pericarditis; case report.
    Indian journal of medical sciences, 1959, Volume: 13, Issue:2

    Topics: Adrenal Cortex Hormones; Cardiovascular Agents; Glucocorticoids; Humans; Pericarditis, Tuberculous;

1959
Tuberculous pericarditis.
    The Journal of infection, 1980, Volume: 2, Issue:4

    Topics: Adolescent; Adult; Aged; Antitubercular Agents; Child; Drug Therapy, Combination; Female; Humans; Ma

1980
Improvement of tuberculous pericardial effusion by steroid.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 1980, Volume: 63, Issue:12

    Topics: Adult; Humans; Male; Pericardial Effusion; Pericarditis, Tuberculous; Prednisolone; Tuberculosis, Ca

1980
Tuberculous pericarditis.
    BMJ (Clinical research ed.), 1994, Feb-19, Volume: 308, Issue:6927

    Topics: Adolescent; Humans; Male; Pericarditis, Tuberculous; Prednisolone

1994
Constrictive pericarditis in patients with tuberculous pericarditis.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 1999, Volume: 98, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Antitubercular Agents; Drug Therapy, Combi

1999
Tuberculous pericarditis and HIV infection.
    Heart (British Cardiac Society), 2000, Volume: 84, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Anti-Inflammatory Agents; Drug Interactions; Drug Therapy, Co

2000
Concurrent steroid and rifampicin therapy.
    British medical journal, 1979, Apr-14, Volume: 1, Issue:6169

    Topics: Adult; Drug Interactions; Humans; Male; Pericarditis, Tuberculous; Prednisolone; Rifampin; Tuberculo

1979
[A case of aortitis syndrome complicated by pericarditis].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1990, Feb-10, Volume: 79, Issue:2

    Topics: Adult; Antitubercular Agents; Aortic Arch Syndromes; Female; Humans; Pericarditis, Tuberculous; Pred

1990