prednisolone has been researched along with Pain, Postoperative in 31 studies
Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.
Pain, Postoperative: Pain during the period after surgery.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This single-centre randomized, double-blind, placebo-controlled clinical trial assessed the effect of a preoperative, single, oral dose of prednisolone on postoperative pain and postoperative analgesic intake in patients with symptomatic, irreversible pulpitis in mandibular molars." | 9.27 | The effect of preoperative oral administration of prednisolone on postoperative pain in patients with symptomatic irreversible pulpitis: a single-centre randomized controlled trial. ( Abdel-Mawgoud, A; AbdelGhaffar, S; AbouZeid, M; Amin, S; Elkhadem, A; Ezzat, K; Hassan, A; Khamis, D; Mamdouh, A; Ramadan, M, 2018) |
| "To compare the efficacy of two formulations of prednisolone acetate 1% in reducing postoperative inflammation in patients having primary phacoemulsification surgery with IOL implantation." | 9.12 | Clinical comparison of two topical prednisolone acetate 1% formulations in reducing inflammation after cataract surgery. ( Donnenfeld, ED; Raizman, MB; Weinstein, AJ, 2007) |
| "Pre-medication with either single dose piroxicam or prednisolone was able to prevent post-endodontic pain in patients with symptomatic irreversible pulpitis." | 5.51 | Effectiveness of Single Dose Premedication of Piroxicam and Prednisolone on Post Endodontic Pain in One Visit Root Canal Treatment: A Randomized Clinical Trial. ( Ahmed, N; Ahmed, S; Akhtar, H; Shakoor Abbasi, M; Tanwir, A; Wahid, U, 2022) |
| "This single-centre randomized, double-blind, placebo-controlled clinical trial assessed the effect of a preoperative, single, oral dose of prednisolone on postoperative pain and postoperative analgesic intake in patients with symptomatic, irreversible pulpitis in mandibular molars." | 5.27 | The effect of preoperative oral administration of prednisolone on postoperative pain in patients with symptomatic irreversible pulpitis: a single-centre randomized controlled trial. ( Abdel-Mawgoud, A; AbdelGhaffar, S; AbouZeid, M; Amin, S; Elkhadem, A; Ezzat, K; Hassan, A; Khamis, D; Mamdouh, A; Ramadan, M, 2018) |
| "A single preoperative oral administration of ≤20 mg prednisolone had no significant effect on postoperative symptoms of pain, facial oedema, or gastrointestinal upset, or on masticatory symptoms, trismus, or swallowing discomfort in mandibular third molar surgery." | 5.14 | Effect of preoperative prednisolone on clinical postoperative symptoms after surgical extractions of mandibular third molars. ( Byun, IY; Choi, YS; Kang, SH; Kim, MK, 2010) |
| "The purpose of this study was to evaluate the effect of a single intramuscular dose of prednisolone and the prednisolone-diclofenac combination on postoperative pain, trismus, and edema after the removal of third molars." | 5.12 | The effect of a single dose prednisolone with and without diclofenac on pain, trismus, and swelling after removal of mandibular third molars. ( Buyukkurt, MC; Gungormus, M; Kaya, O, 2006) |
| "To compare the efficacy of two formulations of prednisolone acetate 1% in reducing postoperative inflammation in patients having primary phacoemulsification surgery with IOL implantation." | 5.12 | Clinical comparison of two topical prednisolone acetate 1% formulations in reducing inflammation after cataract surgery. ( Donnenfeld, ED; Raizman, MB; Weinstein, AJ, 2007) |
| "Forty-seven patients with postdiscectomy sciatica but no evidence of compression by computed tomography or magnetic resonance imaging were included in a multicenter, randomized, controlled, parallel-group study comparing forceful injections of saline (20 ml) with or without prednisolone acetate (125 mg) to epidural prednisolone acetate (125 mg) alone." | 5.09 | Forceful sacrococcygeal injections in the treatment of postdiscectomy sciatica. A controlled study versus glucocorticoid injections. ( Blévin, S; Chalès, G; Duquesnoy, B; Duvauferrier, R; Fallut, M; Guggenbuhl, P; Kuntz, JL; Le Goff, P; Le Loët, X; Marty, M; Meadeb, J; Rozenberg, S; Sebert, JL, 2001) |
| "Independent of postoperative pain management, patients developed significant pain up to the day 4 following surgery." | 3.01 | Does ibuprofen, prednisolone, or amoxicillin reduce post-tonsillectomy pain in children? A prospective randomized controlled trial. ( Anselmo-Lima, WT; Caetano, JVB; Carenzi, LR; de Azevedo, CB; Küpper, DS; Queiroz, DLC; Tamashiro, E; Valera, FCP, 2021) |
| "Preoperative and postoperative pain was evaluated using a visual analog scale at 6 time intervals." | 2.84 | Comparative Evaluation of Premedication with Ketorolac and Prednisolone on Postendodontic Pain: A Double-blind Randomized Controlled Trial. ( Kirthiga, M; Praveen, R; Thakur, S, 2017) |
| "The intraocular pressures were measured at regular intervals during the 6-months follow-up period." | 2.80 | Influence on intraocular pressure of anti-inflammatory treatments after selective laser trabeculoplasty. ( Anctil, JL; Champagne, S; Des Marchais, B; Goyette, A; Lajoie, C, 2015) |
| "All dogs received systemic postoperative pain managements with oral tramadol (4 mg/kg) and prednisolone (0." | 2.78 | Effect of topical administration of 0.8% nalbuphine on the cornea in dogs after phacoemulsification. ( Chang, SH; Chi, TT; Lee, CH; Lin, SL; Wang, HC, 2013) |
| "Postoperative pain, facial swelling and trismus were evaluated." | 2.75 | The effect of prednisolone on reduction of complaints after impacted third molar removal. ( Leibur, E; Tamme, T; Tiigimae-Saar, J, 2010) |
| "Postoperative pain was assessed after 6, 12, and 24 hours by using a visual analogue scale." | 2.75 | Effect of pretreatment prednisolone on postendodontic pain: a double-blind parallel-randomized clinical trial. ( Jalalzadeh, SM; Mamavi, A; Pochapski, MT; Santos, FA; Shahriari, S, 2010) |
| "Background and purpose - Immediate postoperative pain management offered in knee arthroplasty is suboptimal in up to one-third of patients resulting in high opiate consumption and delayed discharge." | 2.58 | Perioperative adjuvant corticosteroids for postoperative analgesia in knee arthroplasty. ( Hamilton, TW; Mohammad, HR; Murray, D; Pandit, H; Strickland, L; Trivella, M, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (9.68) | 18.7374 |
| 1990's | 4 (12.90) | 18.2507 |
| 2000's | 7 (22.58) | 29.6817 |
| 2010's | 14 (45.16) | 24.3611 |
| 2020's | 3 (9.68) | 2.80 |
| Authors | Studies |
|---|---|
| Hovanesian, JA | 1 |
| Donnenfeld, ED | 2 |
| Tanwir, A | 1 |
| Ahmed, S | 1 |
| Akhtar, H | 1 |
| Wahid, U | 1 |
| Shakoor Abbasi, M | 1 |
| Ahmed, N | 1 |
| de Azevedo, CB | 1 |
| Valera, FCP | 1 |
| Carenzi, LR | 1 |
| Küpper, DS | 1 |
| Caetano, JVB | 1 |
| Queiroz, DLC | 1 |
| Anselmo-Lima, WT | 1 |
| Tamashiro, E | 1 |
| Praveen, R | 1 |
| Thakur, S | 1 |
| Kirthiga, M | 1 |
| Elkhadem, A | 1 |
| Ezzat, K | 1 |
| Ramadan, M | 1 |
| AbdelGhaffar, S | 1 |
| Khamis, D | 1 |
| Hassan, A | 1 |
| Abdel-Mawgoud, A | 1 |
| Mamdouh, A | 1 |
| AbouZeid, M | 1 |
| Amin, S | 1 |
| Brignardello-Petersen, R | 1 |
| Mohammad, HR | 1 |
| Hamilton, TW | 1 |
| Strickland, L | 1 |
| Trivella, M | 1 |
| Murray, D | 1 |
| Pandit, H | 1 |
| Veitz-Keenan, A | 1 |
| Ferraiolo, DM | 1 |
| Nagendrababu, V | 1 |
| Pulikkotil, SJ | 1 |
| Jinatongthai, P | 1 |
| Veettil, SK | 1 |
| Teerawattanapong, N | 1 |
| Gutmann, JL | 1 |
| Kanazawa, H | 1 |
| Kotoda, A | 1 |
| Akimoto, T | 1 |
| Shinozaki, T | 1 |
| Inoue, M | 1 |
| Sugimoto, H | 1 |
| Kusano, E | 1 |
| Lee, CH | 1 |
| Lin, SL | 1 |
| Chi, TT | 1 |
| Chang, SH | 1 |
| Wang, HC | 1 |
| Park, SK | 1 |
| Kim, J | 1 |
| Kim, JM | 1 |
| Yeon, JY | 1 |
| Shim, WS | 1 |
| Lee, DW | 1 |
| Aveline, C | 1 |
| Le Hetet, H | 1 |
| Le Roux, A | 1 |
| Bonnet, F | 1 |
| Champagne, S | 1 |
| Anctil, JL | 1 |
| Goyette, A | 1 |
| Lajoie, C | 1 |
| Des Marchais, B | 1 |
| Thompson, CA | 1 |
| Tiigimae-Saar, J | 1 |
| Leibur, E | 1 |
| Tamme, T | 1 |
| Jalalzadeh, SM | 1 |
| Mamavi, A | 1 |
| Shahriari, S | 1 |
| Santos, FA | 1 |
| Pochapski, MT | 1 |
| Kang, SH | 1 |
| Choi, YS | 1 |
| Byun, IY | 1 |
| Kim, MK | 1 |
| Walsh, EM | 1 |
| LOCKE, RK | 1 |
| STRAUSS, H | 1 |
| Horner, B | 1 |
| El-Muttardi, N | 1 |
| Mercer, D | 1 |
| Buyukkurt, MC | 1 |
| Gungormus, M | 1 |
| Kaya, O | 1 |
| Raizman, MB | 1 |
| Weinstein, AJ | 1 |
| Beck-Mannagetta, J | 1 |
| Wepner, F | 1 |
| Revel, M | 1 |
| Auleley, GR | 1 |
| Alaoui, S | 1 |
| Nguyen, M | 1 |
| Duruoz, T | 1 |
| Eck-Michaud, S | 1 |
| Roux, C | 1 |
| Amor, B | 1 |
| Lin, TC | 1 |
| Lui, MT | 1 |
| Chang, RC | 1 |
| Rasmussen, S | 1 |
| Larsen, AS | 1 |
| Thomsen, ST | 1 |
| Kehlet, H | 1 |
| Palme, CE | 1 |
| Tomasevic, P | 1 |
| Pohl, DV | 1 |
| Meadeb, J | 1 |
| Rozenberg, S | 1 |
| Duquesnoy, B | 1 |
| Kuntz, JL | 1 |
| Le Loët, X | 1 |
| Sebert, JL | 1 |
| Le Goff, P | 1 |
| Fallut, M | 1 |
| Marty, M | 1 |
| Blévin, S | 1 |
| Guggenbuhl, P | 1 |
| Chalès, G | 1 |
| Duvauferrier, R | 1 |
| Gersema, L | 1 |
| Baker, K | 1 |
| Chance, K | 1 |
| Lin, L | 1 |
| Shovlin, FE | 1 |
| Skribner, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The D3 Study: Drug Delivery vs Drops - A Prospective Clinical Study Evaluating Dexycu vs Prednisolone Acetate 1% in Controlling Post-operative Pain and Inflammation in Patients Undergoing Sequential Cataract Surgery[NCT04273282] | Phase 4 | 31 participants (Actual) | Interventional | 2019-12-16 | Completed | ||
| Effectiveness of Single Dose Pre Medication of Piroxicam and Prednisolone on Post Endodontic Pain After a One Visit Root Canal Treatment. Randomized Trial .[NCT04124822] | Phase 2/Phase 3 | 60 participants (Actual) | Interventional | 2018-05-30 | Completed | ||
| Pretreatment Aceclofenac Effect on Pain and Analgesic Intake After Endodontic Treatment: A Randomized, Double-blind, Placebo-controlled Trial[NCT03335007] | Phase 2/Phase 3 | 70 participants (Actual) | Interventional | 2015-05-31 | Completed | ||
| The Effect of Premedication With Curcumin on Post-Operative Pain in Single Visit Endodontic Treatment of Acute Pulpitis in Mandibular Molars: A Randomized Controlled Trial[NCT04012424] | 44 participants (Actual) | Interventional | 2019-08-01 | Completed | |||
| Methylprednisolone Taper to Treat Delayed Post-Operative Recovery After Total Knee Arthroplasty: a Double-Blind Randomized Controlled Trial[NCT05113901] | Phase 4 | 4 participants (Actual) | Interventional | 2022-03-03 | Terminated (stopped due to Extremely low participation, decided to focus on similar study instead) | ||
| The Effect of Electroacupuncture (EA) on the Success of Inferior Alveolar Nerve Block (IANB) and Post-operative Pain Relief in Mandibular Molar With Symptomatic Irreversible Pulpitis (SIP) Among Malaysians: A Study Protocol for Randomized Double-Blinded C[NCT04804761] | 20 participants (Anticipated) | Interventional | 2023-01-01 | Recruiting | |||
| Effect of Steroids on Post-tonsillectomy Morbidities[NCT02401529] | Phase 2 | 100 participants (Actual) | Interventional | 2013-01-31 | Completed | ||
| Three-dimensional Facial Swelling Evaluation of Pre-operative Single-dose of Prednisone in Third Molar Surgery: a Split-mouth Randomized Controlled Trial[NCT05830747] | Phase 4 | 34 participants (Actual) | Interventional | 2022-02-01 | Completed | ||
| The Effect of Preoperative Oral Administration of Prednisolone on Postoperative Pain in Patients With Symptomatic Irreversible Pulpitis: A Single Center Randomized Controlled Trial[NCT02819648] | Phase 4 | 400 participants (Actual) | Interventional | 2012-06-30 | Completed | ||
| Post-operative Course of Dexamethasone to Reduce Tonsillectomy Morbidity[NCT04879823] | Phase 3 | 300 participants (Anticipated) | Interventional | 2021-08-05 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Adverse outcomes including infection, avascular necrosis, and 90-day readmission rates (NCT05113901)
Timeframe: within 90 days after initial total knee arthroplasty
| Intervention | Participants (Count of Participants) |
|---|---|
| Methylprednisolone Taper | 0 |
| Placebo Taper | 0 |
Manipulations under anesthesia (MUAs) following total knee arthroplasty surgery and treatment (NCT05113901)
Timeframe: within 90 days after initial total knee arthroplasty
| Intervention | Participants (Count of Participants) |
|---|---|
| Methylprednisolone Taper | 0 |
| Placebo Taper | 0 |
Single Assessment Numeric Evaluation (SANE), a single-question patient rating of 0-100, scoring their function to the area being treated. Zero represents a poor functional knee and 100 is the best functioning. (NCT05113901)
Timeframe: 6 weeks after treatment
| Intervention | score on a scale (Mean) |
|---|---|
| Methylprednisolone Taper | 89.5 |
UCLA activity score, on a scale of 1 to 10 where 10 is the most active patient with examples of activities (NCT05113901)
Timeframe: 6 weeks after treatment
| Intervention | score on a scale (Mean) |
|---|---|
| Methylprednisolone Taper | 5.25 |
VR-12: Assesses physical functioning, physical/ mental limitations. Scored as summary of mental and physical, measure in standard deviations. The scale range is 0 to 100, where a score of 100 represents the best physical and mental health and zero is the worst outcome. (NCT05113901)
Timeframe: 6 weeks after treatment
| Intervention | score on a scale (Mean) |
|---|---|
| Methylprednisolone Taper | 50.28 |
Forgotten Joint Score (FJS) is a survey scored ranging from 0 to 100, where a high score indicates a high degree of a forgetting they have an artificial joint, which is an ideal outcome. (NCT05113901)
Timeframe: 6 weeks after treatment
| Intervention | score on a scale (Mean) |
|---|---|
| Methylprednisolone Taper | 57.82 |
Knee Injury and Osteoarthritis Outcome Score for Joint Replacement (KOOS JR), a survey given to patients standard of care containing 7 questions. The score ranges from 0 to 100 where zero represents total disability and 100 represents a perfect knee health. (NCT05113901)
Timeframe: 6 weeks after treatment
| Intervention | score on a scale (Mean) |
|---|---|
| Methylprednisolone Taper | 72.12 |
Knee Injury and Osteoarthritis Outcome Score for Joint Replacement (KOOS JR), a survey given to patients standard of care containing 7 questions. The score ranges from 0 to 100 where zero represents total disability and 100 represents a perfect knee health. (NCT05113901)
Timeframe: pre treatment
| Intervention | score on a scale (Mean) |
|---|---|
| Methylprednisolone Taper | 50.04 |
Single Assessment Numeric Evaluation (SANE), a single-question patient rating of 0-100, scoring their function to the area being treated. Zero represents a poor functional knee and 100 is the best functioning. (NCT05113901)
Timeframe: pre treatment
| Intervention | score on a scale (Mean) |
|---|---|
| Methylprednisolone Taper | 29.5 |
Veterans Rand 12-Item Health Survey (VR-12), a survey of 12 questions to measure health relating to patient's quality of life. Scored as summary of mental and physical, measure in standard deviations. The scale range is 0 to 100, where a score of 100 represents the best physical and mental health and zero is the worst outcome. (NCT05113901)
Timeframe: pre treatment
| Intervention | score on a scale (Mean) |
|---|---|
| Methylprednisolone Taper | 38.73 |
Forgotten Joint Score (FJS) is a survey scored ranging from 0 to 100, where a high score indicates a high degree of a forgetting they have an artificial joint, which is an ideal outcome. (NCT05113901)
Timeframe: pre treatment
| Intervention | score on a scale (Mean) |
|---|---|
| Methylprednisolone Taper | 91.67 |
UCLA activity score, on a scale of 1 to 10 where 10 is the most active patient with examples of activities (NCT05113901)
Timeframe: pre treatment
| Intervention | score on a scale (Mean) |
|---|---|
| Methylprednisolone Taper | 4.25 |
"Knee society score (KSS); done standard of care on a scale of 0-100, where 100 means a more functional knee.~**Please note, the study was terminated early, only 4 subjects were enrolled and none were randomized to the placebo group. At 3 weeks post treatment, only 3 of the 4 subjects enrolled were still part of the study." (NCT05113901)
Timeframe: 3 weeks post treatment
| Intervention | score on a scale (Mean) |
|---|---|
| Methylprednisolone Taper | 68.33 |
"Knee society score (KSS); done standard of care on a scale of 0-100, where 100 means a more functional knee.~**Please note, the study was terminated early, only 4 subjects were enrolled and none were randomized to the placebo group. This is a standard of care survey available on all subjects." (NCT05113901)
Timeframe: 6 weeks post treatment
| Intervention | score on a scale (Mean) |
|---|---|
| Methylprednisolone Taper | 78.75 |
"Using daily defense and veterans pain rating scale (DVPRS) on a scale of 1 to 10, 10 being the worst.~Please note, only one patient made it to the 6 week post treatment mark of the 4 enrolled. The study was terminated and none of the patients were randomized to the placebo group. All other patients followed up but were not interested in continuing. No range could be provided given only one subject answered and completed this visit" (NCT05113901)
Timeframe: 6 weeks post treatment
| Intervention | score on a scale (Mean) |
|---|---|
| Methylprednisolone Taper | 1.93 |
"Knee society score (KSS); done standard of care on a scale of 0-100, where 100 means a more functional knee~**Please note, the study was terminated early, only 4 subjects were enrolled and none were randomized to the placebo group." (NCT05113901)
Timeframe: pre treatment
| Intervention | score on a scale (Mean) |
|---|---|
| Methylprednisolone Taper | 66.25 |
"Using Daily Visual Analogue Scale (VAS) pain score, which measures intensity of pain on a scale of 0 (no pain) to 10 (worst pain possible).~**Please note, this study was terminated early, only enrolling 4 patients, none were randomized to the placebo group." (NCT05113901)
Timeframe: Days 1 through 6 following treatment
| Intervention | score on a scale (Mean) | |||||
|---|---|---|---|---|---|---|
| Day 1 | Day 2 | Day 3 | Day 4 | Day 5 | Day 6 | |
| Methylprednisolone Taper | 2.33 | 3 | 1.33 | 1.33 | 1.67 | 2.3 |
"Range of motion (ROM) from pre-treatment to six weeks following treatment. Patients started treatment after total knee replacement surgery and presented to clinic with at least one inclusion criteria to be enrolled. Range of motion in degrees is taken at each visit by a clinician (standard of care), starting at zero degrees (straight leg) to about 135 degrees. The ROM was documented as part of consenting and enrollment into study. Subjects returned to the office at 6 weeks post treatment where ROM was performed in a clinic setting once again and documented. ROM is done using a goniometer by a clinician in each clinic.~This study was terminated early, therefore of the 4 enrolled, zero were randomized to the placebo group. Only 1 of the four subjects completed the 6 weeks, however, ROM was captured on all as standard of care." (NCT05113901)
Timeframe: Baseline, Week 6 Following Treatment
| Intervention | Range of Motion in Degrees (Mean) | |
|---|---|---|
| Pre treatment | Post treatment | |
| Methylprednisolone Taper | 82.5 | 112 |
adequacy of meals (inadequate, adequate) (NCT02401529)
Timeframe: 3 days
| Intervention | participants (Number) | |
|---|---|---|
| inadequate | adequate | |
| IV Dexamethasone and Oral Prednisolone | 16 | 34 |
| Placebo | 27 | 23 |
average frequency of meals (1 meal, 2 meals, if more specify) (NCT02401529)
Timeframe: average number of meals consumed per day for the 1st three days post-surgery
| Intervention | participants (Number) | ||
|---|---|---|---|
| 1 meal | 2 meals | 3 meals | |
| IV Dexamethasone and Oral Prednisolone | 2 | 20 | 28 |
| Placebo | 1 | 34 | 15 |
Postoperative nausea duration (no nausea,1 day, 2 days, 3 days, 4 days, if more specify) (NCT02401529)
Timeframe: 7 days
| Intervention | participants (Number) | |||
|---|---|---|---|---|
| no nausea | one day | two days | three days | |
| IV Dexamethasone and Oral Prednisolone | 33 | 3 | 14 | 0 |
| Placebo | 21 | 8 | 15 | 6 |
4 selections (1 day, 2 days, 3 days, if more specify) (NCT02401529)
Timeframe: number of days at which pain was experienced within the the 1st sevn days post -surgery
| Intervention | participants (Number) | ||
|---|---|---|---|
| one day | two days | three days | |
| IV Dexamethasone and Oral Prednisolone | 36 | 11 | 3 |
| Placebo | 23 | 19 | 8 |
5 grades (pain free, low disability and low intensity, low disability and high intensity, high disability and moderate intensity, high disability and severly limiting) (NCT02401529)
Timeframe: The severest pain grade felt within a week
| Intervention | participants (Number) | ||
|---|---|---|---|
| Low disability and low intensity | high disability and moderate intensity | high disability and high intensity | |
| IV Dexamethasone and Oral Prednisolone | 37 | 13 | 0 |
| Placebo | 26 | 21 | 3 |
Postoperative nausea occurence (yes, no) (NCT02401529)
Timeframe: 7 days
| Intervention | participants (Number) | |
|---|---|---|
| yes | no | |
| IV Dexamethasone and Oral Prednisolone | 17 | 33 |
| Placebo | 29 | 21 |
Postoperative vomiting occurrence (yes, no) (NCT02401529)
Timeframe: 7 days
| Intervention | participants (Number) | |
|---|---|---|
| yes | no | |
| IV Dexamethasone and Oral Prednisolone | 25 | 25 |
| Placebo | 36 | 14 |
feeding onset (1st day i. surgery day, 2nd day, 3rd day) (NCT02401529)
Timeframe: Onset of 1st post-operative oral intake recorded within the 1st 3days post-surgery
| Intervention | participants (Number) | |
|---|---|---|
| surgery day | 1st day after surgery | |
| IV Dexamethasone and Oral Prednisolone | 46 | 4 |
| Placebo | 37 | 13 |
Postoperative nausea onset (no nausea, immediate, 1st day, 2nd day, 3rd day, 4th day, 5th day, 6th day, 7th day) (NCT02401529)
Timeframe: onset of 1st ocurence of nausea attack within the 1st week post-surgery
| Intervention | participants (Number) | |||
|---|---|---|---|---|
| no nausea | immediately | 1st day | immediately and 1st day | |
| IV Dexamethasone and Oral Prednisolone | 33 | 10 | 4 | 3 |
| Placebo | 21 | 8 | 11 | 10 |
Postoperative vomiting number of attacks (no vomiting,1, 2, 3, if more specify) (NCT02401529)
Timeframe: total number of post-operative vomiting episodes which were experienced within the 1st week post-surgery
| Intervention | participants (Number) | ||||
|---|---|---|---|---|---|
| no vomiting | once | twice | three times | more than 3 times | |
| IV Dexamethasone and Oral Prednisolone | 25 | 13 | 7 | 4 | 1 |
| Placebo | 14 | 9 | 19 | 8 | 0 |
3 reviews available for prednisolone and Pain, Postoperative
| Article | Year |
|---|---|
Perioperative adjuvant corticosteroids for postoperative analgesia in knee arthroplasty.
Topics: Adrenal Cortex Hormones; Analgesics; Arthroplasty, Replacement, Knee; Humans; Pain, Postoperative; P | 2018 |
Efficacy and Safety of Oral Premedication on Pain after Nonsurgical Root Canal Treatment: A Systematic Review and Network Meta-analysis of Randomized Controlled Trials.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Databases, B | 2019 |
Use of corticosteroids in oral surgery.
Topics: Adrenal Cortex Hormones; Betamethasone; Chi-Square Distribution; Clinical Trials as Topic; Dexametha | 1992 |
19 trials available for prednisolone and Pain, Postoperative
| Article | Year |
|---|---|
Intracameral dexamethasone 9% vs prednisolone acetate 1% in controlling postoperative pain and inflammation in patients undergoing cataract surgery.
Topics: Cataract; Cataract Extraction; Dexamethasone; Humans; Inflammation; Moxifloxacin; Ophthalmic Solutio | 2022 |
Effectiveness of Single Dose Premedication of Piroxicam and Prednisolone on Post Endodontic Pain in One Visit Root Canal Treatment: A Randomized Clinical Trial.
Topics: Dental Pulp Cavity; Humans; Pain, Postoperative; Piroxicam; Prednisolone; Premedication; Pulpitis | 2022 |
Does ibuprofen, prednisolone, or amoxicillin reduce post-tonsillectomy pain in children? A prospective randomized controlled trial.
Topics: Amoxicillin; Analgesics, Non-Narcotic; Child; Humans; Ibuprofen; Pain, Postoperative; Prednisolone; | 2021 |
Comparative Evaluation of Premedication with Ketorolac and Prednisolone on Postendodontic Pain: A Double-blind Randomized Controlled Trial.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind M | 2017 |
Comparative Evaluation of Premedication with Ketorolac and Prednisolone on Postendodontic Pain: A Double-blind Randomized Controlled Trial.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind M | 2017 |
Comparative Evaluation of Premedication with Ketorolac and Prednisolone on Postendodontic Pain: A Double-blind Randomized Controlled Trial.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind M | 2017 |
Comparative Evaluation of Premedication with Ketorolac and Prednisolone on Postendodontic Pain: A Double-blind Randomized Controlled Trial.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind M | 2017 |
The effect of preoperative oral administration of prednisolone on postoperative pain in patients with symptomatic irreversible pulpitis: a single-centre randomized controlled trial.
Topics: Administration, Oral; Adult; Analgesics; Anti-Inflammatory Agents; Double-Blind Method; Drug Utiliza | 2018 |
Effect of topical administration of 0.8% nalbuphine on the cornea in dogs after phacoemulsification.
Topics: Administration, Topical; Animals; Dogs; Nalbuphine; Pain, Postoperative; Phacoemulsification; Predni | 2013 |
Effects of oral prednisolone on recovery after tonsillectomy.
Topics: Adenoidectomy; Administration, Oral; Adolescent; Adult; Child; Child, Preschool; Cohort Studies; End | 2015 |
Influence on intraocular pressure of anti-inflammatory treatments after selective laser trabeculoplasty.
Topics: Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Combined Modalit | 2015 |
The effect of prednisolone on reduction of complaints after impacted third molar removal.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase | 2010 |
Effect of pretreatment prednisolone on postendodontic pain: a double-blind parallel-randomized clinical trial.
Topics: Administration, Oral; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Bismuth | 2010 |
Effect of preoperative prednisolone on clinical postoperative symptoms after surgical extractions of mandibular third molars.
Topics: Adult; Analysis of Variance; Edema; Female; Glucocorticoids; Humans; Male; Mandible; Molar, Third; P | 2010 |
The effect of a single dose prednisolone with and without diclofenac on pain, trismus, and swelling after removal of mandibular third molars.
Topics: Adolescent; Adult; Analysis of Variance; Anti-Inflammatory Agents; Diclofenac; Double-Blind Method; | 2006 |
Clinical comparison of two topical prednisolone acetate 1% formulations in reducing inflammation after cataract surgery.
Topics: Administration, Topical; Anti-Inflammatory Agents; Cataract Extraction; Chemistry, Pharmaceutical; D | 2007 |
Forceful epidural injections for the treatment of lumbosciatic pain with post-operative lumbar spinal fibrosis.
Topics: Adult; Diskectomy; Double-Blind Method; Female; Fibrosis; Humans; Injections, Epidural; Laminectomy; | 1996 |
Premedication with diclofenac and prednisolone to prevent postoperative pain and swelling after third molar removal.
Topics: Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind M | 1996 |
Intra-articular glucocorticoid, bupivacaine and morphine reduces pain, inflammatory response and convalescence after arthroscopic meniscectomy.
Topics: Adolescent; Adult; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents; Arthroscopy; Bu | 1998 |
Evaluating the effects of oral prednisolone on recovery after tonsillectomy: a prospective, double-blind, randomized trial.
Topics: Adolescent; Child; Child, Preschool; Double-Blind Method; Female; Glucocorticoids; Humans; Male; Pai | 2000 |
Forceful sacrococcygeal injections in the treatment of postdiscectomy sciatica. A controlled study versus glucocorticoid injections.
Topics: Adolescent; Adult; Aged; Child; Diskectomy; Double-Blind Method; Epidural Space; Female; Fibrosis; H | 2001 |
Clinical trial of intracanal corticosteroid in root canal therapy.
Topics: Clinical Trials as Topic; Dental Pulp Cavity; Double-Blind Method; Humans; Pain, Postoperative; Pred | 1987 |
9 other studies available for prednisolone and Pain, Postoperative
| Article | Year |
|---|---|
Preoperative prednisolone and ketorolac may result in a small reduction of postoperative endodontic pain compared with placebo.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Humans; Ketorolac; Pain, Postoperative | 2017 |
Single dose oral prednisolone and post-operative endodontic pain.
Topics: Adult; Analgesics; Double-Blind Method; Egypt; Female; Humans; Male; Pain, Postoperative; Prednisolo | 2018 |
Serial Tc-99m MAG3 renography evaluating the recovery of acute kidney injury associated with minimal change nephrotic syndrome.
Topics: Acute Kidney Injury; Aged; Anti-Inflammatory Agents, Non-Steroidal; Disease Susceptibility; Fracture | 2013 |
A survey of the administration of prednisolone versus ibuprofen analgesic protocols after ambulatory tonsillectomy.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-In | 2015 |
New topical corticosteroid treats postoperative ocular pain.
Topics: Contraindications; Drug Approval; Humans; Ophthalmic Solutions; Ophthalmologic Surgical Procedures; | 2008 |
Methods of post-thoracotomy analgesia.
Topics: Analgesia, Epidural; Glucocorticoids; Humans; Pain, Postoperative; Prednisolone; Thoracotomy | 2002 |
THE REDUCTION OF POST OPERATIVE PAIN AND EDEMA IN FOOT SURGERY THROUGH LOCAL INSTILLATION OF CORTICOSTEROIDS.
Topics: Dexamethasone; Edema; Foot; Glucocorticoids; Humans; Pain; Pain, Postoperative; Postoperative Compli | 1964 |
Pyoderma gangrenosum complicating bilateral breast reduction.
Topics: Administration, Oral; Adult; Anti-Infective Agents; Anti-Inflammatory Agents; Betamethasone Valerate | 2004 |
[Post-extraction pain and its treatment with Corti-Dynexan].
Topics: Dequalinium; Drug Combinations; Humans; Pain, Postoperative; Pancreatin; Polyethylene Glycols; Predn | 1983 |