Page last updated: 2024-11-06

prednisolone and Osteoarthritis of Knee

prednisolone has been researched along with Osteoarthritis of Knee in 6 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Research Excerpts

ExcerptRelevanceReference
"Data were analysed from a 6-week, randomized, double-blind, placebo-controlled trial investigating prednisolone treatment in 92 patients with painful inflammatory hand OA."9.51Neuropathic-like pain symptoms in inflammatory hand osteoarthritis lower quality of life and may not decrease under prednisolone treatment. ( Allaart, CF; Böhringer, S; Boonen, AERCH; Kloppenburg, M; Kortekaas, MC; Kroon, FPB; Niesters, M; Reijnierse, M; Riyazi, N; Rosendaal, FR; Starmans-Kool, M; Turkstra, F; van de Stadt, LA; van der Meulen, C; van Zeben, J, 2022)
"To investigate the efficacy of 6 weeks of daily low-dose oral prednisolone in improving pain, mobility, and systemic low-grade inflammation in the short term and whether the effect would be sustained at 12 weeks in older adults with moderate to severe knee osteoarthritis (OA)."9.19Effect of low-dose oral prednisolone on symptoms and systemic inflammation in older adults with moderate to severe knee osteoarthritis: a randomized placebo-controlled trial. ( Abou-Raya, A; Abou-Raya, S; Helmii, M; Khadrawi, T, 2014)
"Data were analysed from a 6-week, randomized, double-blind, placebo-controlled trial investigating prednisolone treatment in 92 patients with painful inflammatory hand OA."5.51Neuropathic-like pain symptoms in inflammatory hand osteoarthritis lower quality of life and may not decrease under prednisolone treatment. ( Allaart, CF; Böhringer, S; Boonen, AERCH; Kloppenburg, M; Kortekaas, MC; Kroon, FPB; Niesters, M; Reijnierse, M; Riyazi, N; Rosendaal, FR; Starmans-Kool, M; Turkstra, F; van de Stadt, LA; van der Meulen, C; van Zeben, J, 2022)
"To investigate the efficacy of 6 weeks of daily low-dose oral prednisolone in improving pain, mobility, and systemic low-grade inflammation in the short term and whether the effect would be sustained at 12 weeks in older adults with moderate to severe knee osteoarthritis (OA)."5.19Effect of low-dose oral prednisolone on symptoms and systemic inflammation in older adults with moderate to severe knee osteoarthritis: a randomized placebo-controlled trial. ( Abou-Raya, A; Abou-Raya, S; Helmii, M; Khadrawi, T, 2014)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's4 (66.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
van der Meulen, C1
van de Stadt, LA1
Kroon, FPB1
Kortekaas, MC1
Boonen, AERCH1
Böhringer, S1
Niesters, M1
Reijnierse, M1
Rosendaal, FR1
Riyazi, N1
Starmans-Kool, M1
Turkstra, F1
van Zeben, J1
Allaart, CF1
Kloppenburg, M1
Abou-Raya, A1
Abou-Raya, S1
Khadrawi, T1
Helmii, M1
Steurer, J1
Malaise, O1
Relic, B1
Charlier, E1
Zeddou, M1
Neuville, S1
Deroyer, C1
Gillet, P1
Louis, E1
Malaise, MG1
de Seny, D1
Umekita, K1
Kaneko, Y1
Yorita, K1
Hashiba, Y1
Matsuda, M1
Miyauchi, S1
Ueno, S1
Takajo, I1
Kusumoto, N1
Nagatomo, Y1
Marutsuka, K1
Okayama, A1
Takahashi, T1
Takemoto, S1
Kiyasu, K1
Yamamoto, H1
Tani, T1
Miyoshi, I1
Taguchi, H1
Moriki, T1
Miyazaki, E1
Enzan, H1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase 4 Study of Low Dose Prednisolone for Knee Osteoarthritis[NCT01619163]Phase 4125 participants (Actual)Interventional2011-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for prednisolone and Osteoarthritis of Knee

ArticleYear
Neuropathic-like pain symptoms in inflammatory hand osteoarthritis lower quality of life and may not decrease under prednisolone treatment.
    European journal of pain (London, England), 2022, Volume: 26, Issue:8

    Topics: Female; Humans; Male; Middle Aged; Osteoarthritis, Knee; Pain; Pain Measurement; Peripheral Nervous

2022
Effect of low-dose oral prednisolone on symptoms and systemic inflammation in older adults with moderate to severe knee osteoarthritis: a randomized placebo-controlled trial.
    The Journal of rheumatology, 2014, Volume: 41, Issue:1

    Topics: Administration, Oral; Aged; Anti-Inflammatory Agents; Double-Blind Method; Female; Humans; Inflammat

2014

Other Studies

4 other studies available for prednisolone and Osteoarthritis of Knee

ArticleYear
[Glucocorticoids effective in patients with knee osteoarthritis in lower dose].
    Praxis, 2014, Jun-04, Volume: 103, Issue:12

    Topics: Anti-Inflammatory Agents; Female; Humans; Inflammation; Male; Osteoarthritis, Knee; Prednisolone

2014
Glucocorticoid-induced leucine zipper (GILZ) is involved in glucocorticoid-induced and mineralocorticoid-induced leptin production by osteoarthritis synovial fibroblasts.
    Arthritis research & therapy, 2016, 10-04, Volume: 18, Issue:1

    Topics: Aged; Aged, 80 and over; Aldosterone; Blotting, Western; Cells, Cultured; Enzyme-Linked Immunosorben

2016
Arthropathy with infiltrate IgG4-positive plasma cells in synovium.
    Rheumatology (Oxford, England), 2012, Volume: 51, Issue:3

    Topics: Aged; Arthralgia; Arthroplasty, Replacement, Knee; Combined Modality Therapy; Female; Humans; Immuno

2012
Treatment for HTLV-I associated arthropathy: a case study and synovial tissue culture analysis.
    Rheumatology international, 2005, Volume: 26, Issue:1

    Topics: Aged; Anti-HIV Agents; Arthritis, Infectious; Arthroscopy; Betamethasone; C-Reactive Protein; CD8-Po

2005