prednisolone has been researched along with Osteoarthritis, Knee in 6 studies
Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.
Osteoarthritis, Knee: Noninflammatory degenerative disease of the knee joint consisting of three large categories: conditions that block normal synchronous movement, conditions that produce abnormal pathways of motion, and conditions that cause stress concentration resulting in changes to articular cartilage. (Crenshaw, Campbell's Operative Orthopaedics, 8th ed, p2019)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Data were analysed from a 6-week, randomized, double-blind, placebo-controlled trial investigating prednisolone treatment in 92 patients with painful inflammatory hand OA." | 9.51 | Neuropathic-like pain symptoms in inflammatory hand osteoarthritis lower quality of life and may not decrease under prednisolone treatment. ( Allaart, CF; Böhringer, S; Boonen, AERCH; Kloppenburg, M; Kortekaas, MC; Kroon, FPB; Niesters, M; Reijnierse, M; Riyazi, N; Rosendaal, FR; Starmans-Kool, M; Turkstra, F; van de Stadt, LA; van der Meulen, C; van Zeben, J, 2022) |
| "To investigate the efficacy of 6 weeks of daily low-dose oral prednisolone in improving pain, mobility, and systemic low-grade inflammation in the short term and whether the effect would be sustained at 12 weeks in older adults with moderate to severe knee osteoarthritis (OA)." | 9.19 | Effect of low-dose oral prednisolone on symptoms and systemic inflammation in older adults with moderate to severe knee osteoarthritis: a randomized placebo-controlled trial. ( Abou-Raya, A; Abou-Raya, S; Helmii, M; Khadrawi, T, 2014) |
| "Data were analysed from a 6-week, randomized, double-blind, placebo-controlled trial investigating prednisolone treatment in 92 patients with painful inflammatory hand OA." | 5.51 | Neuropathic-like pain symptoms in inflammatory hand osteoarthritis lower quality of life and may not decrease under prednisolone treatment. ( Allaart, CF; Böhringer, S; Boonen, AERCH; Kloppenburg, M; Kortekaas, MC; Kroon, FPB; Niesters, M; Reijnierse, M; Riyazi, N; Rosendaal, FR; Starmans-Kool, M; Turkstra, F; van de Stadt, LA; van der Meulen, C; van Zeben, J, 2022) |
| "To investigate the efficacy of 6 weeks of daily low-dose oral prednisolone in improving pain, mobility, and systemic low-grade inflammation in the short term and whether the effect would be sustained at 12 weeks in older adults with moderate to severe knee osteoarthritis (OA)." | 5.19 | Effect of low-dose oral prednisolone on symptoms and systemic inflammation in older adults with moderate to severe knee osteoarthritis: a randomized placebo-controlled trial. ( Abou-Raya, A; Abou-Raya, S; Helmii, M; Khadrawi, T, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| van der Meulen, C | 1 |
| van de Stadt, LA | 1 |
| Kroon, FPB | 1 |
| Kortekaas, MC | 1 |
| Boonen, AERCH | 1 |
| Böhringer, S | 1 |
| Niesters, M | 1 |
| Reijnierse, M | 1 |
| Rosendaal, FR | 1 |
| Riyazi, N | 1 |
| Starmans-Kool, M | 1 |
| Turkstra, F | 1 |
| van Zeben, J | 1 |
| Allaart, CF | 1 |
| Kloppenburg, M | 1 |
| Abou-Raya, A | 1 |
| Abou-Raya, S | 1 |
| Khadrawi, T | 1 |
| Helmii, M | 1 |
| Steurer, J | 1 |
| Malaise, O | 1 |
| Relic, B | 1 |
| Charlier, E | 1 |
| Zeddou, M | 1 |
| Neuville, S | 1 |
| Deroyer, C | 1 |
| Gillet, P | 1 |
| Louis, E | 1 |
| Malaise, MG | 1 |
| de Seny, D | 1 |
| Umekita, K | 1 |
| Kaneko, Y | 1 |
| Yorita, K | 1 |
| Hashiba, Y | 1 |
| Matsuda, M | 1 |
| Miyauchi, S | 1 |
| Ueno, S | 1 |
| Takajo, I | 1 |
| Kusumoto, N | 1 |
| Nagatomo, Y | 1 |
| Marutsuka, K | 1 |
| Okayama, A | 1 |
| Takahashi, T | 1 |
| Takemoto, S | 1 |
| Kiyasu, K | 1 |
| Yamamoto, H | 1 |
| Tani, T | 1 |
| Miyoshi, I | 1 |
| Taguchi, H | 1 |
| Moriki, T | 1 |
| Miyazaki, E | 1 |
| Enzan, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase 4 Study of Low Dose Prednisolone for Knee Osteoarthritis[NCT01619163] | Phase 4 | 125 participants (Actual) | Interventional | 2011-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for prednisolone and Osteoarthritis, Knee
| Article | Year |
|---|---|
Neuropathic-like pain symptoms in inflammatory hand osteoarthritis lower quality of life and may not decrease under prednisolone treatment.
Topics: Female; Humans; Male; Middle Aged; Osteoarthritis, Knee; Pain; Pain Measurement; Peripheral Nervous | 2022 |
Effect of low-dose oral prednisolone on symptoms and systemic inflammation in older adults with moderate to severe knee osteoarthritis: a randomized placebo-controlled trial.
Topics: Administration, Oral; Aged; Anti-Inflammatory Agents; Double-Blind Method; Female; Humans; Inflammat | 2014 |
4 other studies available for prednisolone and Osteoarthritis, Knee
| Article | Year |
|---|---|
[Glucocorticoids effective in patients with knee osteoarthritis in lower dose].
Topics: Anti-Inflammatory Agents; Female; Humans; Inflammation; Male; Osteoarthritis, Knee; Prednisolone | 2014 |
Glucocorticoid-induced leucine zipper (GILZ) is involved in glucocorticoid-induced and mineralocorticoid-induced leptin production by osteoarthritis synovial fibroblasts.
Topics: Aged; Aged, 80 and over; Aldosterone; Blotting, Western; Cells, Cultured; Enzyme-Linked Immunosorben | 2016 |
Arthropathy with infiltrate IgG4-positive plasma cells in synovium.
Topics: Aged; Arthralgia; Arthroplasty, Replacement, Knee; Combined Modality Therapy; Female; Humans; Immuno | 2012 |
Treatment for HTLV-I associated arthropathy: a case study and synovial tissue culture analysis.
Topics: Aged; Anti-HIV Agents; Arthritis, Infectious; Arthroscopy; Betamethasone; C-Reactive Protein; CD8-Po | 2005 |