prednisolone has been researched along with Neuralgia, Sciatic in 25 studies
Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The Oral Steroids In Sciatica (OASIS) trial is a randomised, placebo-controlled, double-blind trial that will evaluate a tapering regimen of oral prednisolone in 200 participants with acute sciatica." | 5.34 | OASIS-a randomised, placebo-controlled trial of oral glucocorticoids for leg pain in patients with acute sciatica: trial protocol. ( Abdel Shaheed, C; Buchbinder, R; Day, RO; Latimer, J; Li, Q; Lin, CC; Liu, C; Maher, CG; McLachlan, AJ; Oliveira, JS; Richards, B, 2020) |
| "Three epidural injections (two day intervals) of 2 ml prednisolone acetate (50 mg) or 2 ml isotonic saline were administered to patients with sciatica presumably due to a disk herniation lasting 15-180 days." | 5.10 | Epidural corticosteroid injections for sciatica: a randomised, double blind, controlled clinical trial. ( Bourgeois, P; Giraudeau, B; Goupille, P; Micheau-Beaugendre, V; Richard, S; Rozenberg, S; Soubrier, M; Thomas, E; Valat, JP, 2003) |
| "Forty-seven patients with postdiscectomy sciatica but no evidence of compression by computed tomography or magnetic resonance imaging were included in a multicenter, randomized, controlled, parallel-group study comparing forceful injections of saline (20 ml) with or without prednisolone acetate (125 mg) to epidural prednisolone acetate (125 mg) alone." | 5.09 | Forceful sacrococcygeal injections in the treatment of postdiscectomy sciatica. A controlled study versus glucocorticoid injections. ( Blévin, S; Chalès, G; Duquesnoy, B; Duvauferrier, R; Fallut, M; Guggenbuhl, P; Kuntz, JL; Le Goff, P; Le Loët, X; Marty, M; Meadeb, J; Rozenberg, S; Sebert, JL, 2001) |
| "Prednisolone was assayed in all samples using high performance liquid chromatography and its binding to plasma proteins was determined using ultrafiltration." | 2.68 | Prednisolone concentrations in cerebrospinal fluid after oral prednisone. Preliminary data. ( Bannwarth, B; D'Yvoire, MB; Dehais, J; Péhourcq, F; Schaeverbeke, T; Vernhes, JP, 1997) |
| "Infiltration procedures are a common treatment of lumbar radiculopathy." | 1.42 | CT-guided infiltration saves surgical intervention and fastens return to work compared to anatomical landmark-guided infiltration in patients with lumbosciatica. ( Buhr, M; Deml, MC; Kabir, K; Pflugmacher, R; Riedel, R; Rommelspacher, Y; Wimmer, MD, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (60.00) | 18.7374 |
| 1990's | 4 (16.00) | 18.2507 |
| 2000's | 3 (12.00) | 29.6817 |
| 2010's | 2 (8.00) | 24.3611 |
| 2020's | 1 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, C | 1 |
| Abdel Shaheed, C | 1 |
| McLachlan, AJ | 1 |
| Latimer, J | 1 |
| Li, Q | 1 |
| Buchbinder, R | 1 |
| Day, RO | 1 |
| Maher, CG | 1 |
| Richards, B | 1 |
| Oliveira, JS | 1 |
| Lin, CC | 1 |
| Deml, MC | 1 |
| Buhr, M | 1 |
| Wimmer, MD | 1 |
| Pflugmacher, R | 1 |
| Riedel, R | 1 |
| Rommelspacher, Y | 1 |
| Kabir, K | 1 |
| Roncoroni, C | 1 |
| Baillet, A | 1 |
| Durand, M | 1 |
| Gaudin, P | 1 |
| Juvin, R | 1 |
| Valat, JP | 2 |
| Giraudeau, B | 2 |
| Rozenberg, S | 3 |
| Goupille, P | 1 |
| Bourgeois, P | 2 |
| Micheau-Beaugendre, V | 1 |
| Soubrier, M | 1 |
| Richard, S | 1 |
| Thomas, E | 1 |
| LOUYOT, P | 2 |
| GAUCHER, A | 2 |
| JEANBLANC, J | 1 |
| MATHIEU, J | 1 |
| SEHGAL, AD | 1 |
| GARDNER, WJ | 1 |
| MERIEL, P | 1 |
| RUFFIE, R | 2 |
| FOURNIE, A | 2 |
| AYROLLES, C | 2 |
| JANSEN, C | 2 |
| SERVERDUPUY, JM | 1 |
| CAILLARD, R | 1 |
| Carrera, GF | 2 |
| Karmochkine, M | 1 |
| Chaibi, P | 1 |
| Rogeaux, O | 1 |
| Koeger, AC | 1 |
| Revel, M | 1 |
| Auleley, GR | 1 |
| Alaoui, S | 1 |
| Nguyen, M | 1 |
| Duruoz, T | 1 |
| Eck-Michaud, S | 1 |
| Roux, C | 1 |
| Amor, B | 1 |
| Bannwarth, B | 1 |
| Schaeverbeke, T | 1 |
| Péhourcq, F | 1 |
| Vernhes, JP | 1 |
| D'Yvoire, MB | 1 |
| Dehais, J | 1 |
| Lafuma, A | 1 |
| Bouvenot, G | 1 |
| Cohen, C | 1 |
| Eschwege, E | 1 |
| Fagnani, F | 1 |
| Vignon, E | 1 |
| Meadeb, J | 1 |
| Duquesnoy, B | 1 |
| Kuntz, JL | 1 |
| Le Loët, X | 1 |
| Sebert, JL | 1 |
| Le Goff, P | 1 |
| Fallut, M | 1 |
| Marty, M | 1 |
| Blévin, S | 1 |
| Guggenbuhl, P | 1 |
| Chalès, G | 1 |
| Duvauferrier, R | 1 |
| Ito, R | 1 |
| Wilbrandt, D | 1 |
| Sawyer, HP | 1 |
| Tsurumi, K | 1 |
| Niwa, G | 1 |
| Hench, PK | 1 |
| Reid, RT | 1 |
| Reames, PM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Safety and Efficacy of Nonsteroidal Antiinflammatory Drug and Glucocorticoids in Acute Sciatica[NCT01816334] | Phase 4 | 50 participants (Actual) | Interventional | 2013-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for prednisolone and Neuralgia, Sciatic
| Article | Year |
|---|---|
Efficacy and tolerance of systemic steroids in sciatica: a systematic review and meta-analysis.
Topics: Adult; Dexamethasone; Female; Glucocorticoids; Humans; Male; Methylprednisolone; Middle Aged; Placeb | 2011 |
6 trials available for prednisolone and Neuralgia, Sciatic
| Article | Year |
|---|---|
OASIS-a randomised, placebo-controlled trial of oral glucocorticoids for leg pain in patients with acute sciatica: trial protocol.
Topics: Acute Pain; Administration, Oral; Adult; Double-Blind Method; Drug Administration Schedule; Humans; | 2020 |
Epidural corticosteroid injections for sciatica: a randomised, double blind, controlled clinical trial.
Topics: Adult; Double-Blind Method; Female; Glucocorticoids; Humans; Injections, Epidural; Isotonic Solution | 2003 |
Forceful epidural injections for the treatment of lumbosciatic pain with post-operative lumbar spinal fibrosis.
Topics: Adult; Diskectomy; Double-Blind Method; Female; Fibrosis; Humans; Injections, Epidural; Laminectomy; | 1996 |
Prednisolone concentrations in cerebrospinal fluid after oral prednisone. Preliminary data.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Blood-Brain Barrier; | 1997 |
A pragmatic cost-effectiveness study of routine epidural corticosteroid injections for lumbosciatic syndrome requiring inhospital management.
Topics: Adolescent; Adult; Cost-Benefit Analysis; Female; Follow-Up Studies; Glucocorticoids; Hospital Costs | 1997 |
Forceful sacrococcygeal injections in the treatment of postdiscectomy sciatica. A controlled study versus glucocorticoid injections.
Topics: Adolescent; Adult; Aged; Child; Diskectomy; Double-Blind Method; Epidural Space; Female; Fibrosis; H | 2001 |
18 other studies available for prednisolone and Neuralgia, Sciatic
| Article | Year |
|---|---|
CT-guided infiltration saves surgical intervention and fastens return to work compared to anatomical landmark-guided infiltration in patients with lumbosciatica.
Topics: Adult; Analgesics; Anatomic Landmarks; Anesthetics, Local; Anti-Inflammatory Agents; Bupivacaine; Fe | 2015 |
[Therapeutic effects of hydrocortancyl in local injections].
Topics: Arthritis; Humans; Injections; Prednisolone; Sciatica | 1958 |
[Intraspinal prednisolone in the treatment of sciatica].
Topics: Humans; Prednisolone; Sciatica | 1959 |
Corticosteroids administered intradurally for relief of sciatica.
Topics: Adrenal Cortex Hormones; Glucocorticoids; Humans; Prednisolone; Pregnadienes; Pregnadienetriols; Pro | 1960 |
[The treatment of sciatic neuralgia and radiculitis by intraspinal injections of cortisone derivatives (hydrocortisone, hydrocortancyl and dexamethasone)].
Topics: Adrenal Cortex Hormones; Cortisone; Dexamethasone; Humans; Hydrocortisone; Injections, Spinal; Predn | 1960 |
[On the treatment of the lumbago-ischial syndrome with a mixed compound injection].
Topics: Back Pain; Injections; Ischium; Low Back Pain; Prednisolone; Procaine; Sciatica | 1961 |
[THE CUFF METHOD FOR THE ANTALGIC EVALUATION OF DIFFERENT DRUGS].
Topics: Aminopyrine; Arthritis; Arthritis, Rheumatoid; Aspirin; Caffeine; Gout; Osteoarthritis; Phenobarbita | 1963 |
[ON IMPROVED CONSERVATIVE TREATMENT OF THE LUMBAGO-SCIATICA SYNDROME].
Topics: Back Pain; Humans; Hyaluronoglucosaminidase; Hydroxocobalamin; Low Back Pain; Prednisolone; Procaine | 1964 |
[The treatment of sciatic neuralgia and radiculitis with intraspinal injections of cortisone derivatives (hydrocortisone, hydrocortancyl and dexamethasone)].
Topics: Cortisone; Dexamethasone; Hydrocortisone; Injections, Spinal; Polyradiculopathy; Prednisolone; Radic | 1960 |
Assessment of the clinically relevant change in pain for patients with sciatica.
Topics: Glucocorticoids; Humans; Pain Measurement; Prednisolone; Sciatica; Treatment Outcome | 2004 |
Lumbar facet joint injection in low back pain and sciatica: preliminary results.
Topics: Adult; Aged; Anesthetics, Local; Back Pain; Female; Fluoroscopy; Humans; Injections, Intra-Articular | 1980 |
Lumbar facet joint injection in low back pain and sciatica: description of technique.
Topics: Anesthetics, Local; Back Pain; Fluoroscopy; Humans; Injections, Intra-Articular; Joint Diseases; Lid | 1980 |
[Chemical meningitis simulating infectious meningitis after intradural injection of corticosteroids].
Topics: Adult; Diagnosis, Differential; Humans; Injections, Epidural; Male; Meningitis, Aseptic; Prednisolon | 1993 |
The treatment of low back pain and sciatica with epidural corticosteroids injection and its pathophysiological basis.
Topics: Back Pain; Dura Mater; Humans; Indicator Dilution Techniques; Injections; Iodine Radioisotopes; Phen | 1971 |
[Contribution on intrathecal corticoid therapy (Compiled report of 144 cases)].
Topics: Adrenal Cortex Hormones; Arachnoiditis; Dexamethasone; Encephalomyelitis; Encephalomyelitis, Acute D | 1967 |
A method of treating sciatic pain.
Topics: Adult; Aged; Dexamethasone; Female; Humans; Hydrocortisone; Male; Middle Aged; Prednisolone; Sciatic | 1970 |
[Clinical picture and treatment of sciatica in the aged].
Topics: Aged; Female; Humans; Intervertebral Disc Displacement; Male; Middle Aged; Prednisolone; Radiography | 1968 |
Dissecting popliteal cyst simulating thrombophlebitis.
Topics: Aged; Diagnosis, Differential; Humans; Injections, Intra-Articular; Knee Joint; Male; Methylpredniso | 1966 |