Page last updated: 2024-11-06

prednisolone and Nephrosis

prednisolone has been researched along with Nephrosis in 46 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Nephrosis: Pathological processes of the KIDNEY without inflammatory or neoplastic components. Nephrosis may be a primary disorder or secondary complication of other diseases. It is characterized by the NEPHROTIC SYNDROME indicating the presence of PROTEINURIA and HYPOALBUMINEMIA with accompanying EDEMA.

Research Excerpts

ExcerptRelevanceReference
"The present experiment was designed to investigate the role of peripheral dopamine D1-like receptors and to evaluate the prophylactic effect of zelandopam, a dopamine D1-like receptor agonist, on puromycin aminonucleoside (PA)-induced nephrosis in rats."7.73Effect of zelandopam, a dopamine D1-like receptor agonist, in puromycin aminonucleoside nephrosis rats. ( Aoki, M; Tanaka, A; Yatsu, T, 2005)
" We conclude that changes in the clearance of prednisolone and altered protein binding might account for some of the variability in both therapeutic responses and the incidence of toxicity in patients treated with standard dosage regimens."5.28Pharmacokinetics of prednisolone in children with nephrosis. ( Bowmer, CJ; Brocklebank, JT; Miller, PF; Wheeldon, J, 1990)
" The purpose of this study was to investigate possible correlations between the pharmacokinetic values of prednisolone and the main clinical criteria of effectiveness and safety."5.27[Pharmacokinetics of prednisolone in children. Study of a correlation with tolerability and therapeutic effect in nephrosis]. ( Baron, S; Bensman, A; Raux Demay, MC; Vasmant, D, 1988)
"A persistent proteinuria is commonly observed in nephrotic patient with focal segmental glomerulosclerosis (FSGS) under treatment with prednisolone+/-cyclophosphamide or with vasodilators (ACEI+AII receptor antagonist, calcium channel blocker and antiplatelet agent)."5.11Ganoderma lucidum suppresses endothelial cell cytotoxicity and proteinuria in persistent proteinuric focal segmental glomerulosclerosis (FSGS) nephrosis. ( Butthep, P; Futrakul, N; Futrakul, P; Jetanalin, P; Panichakul, T; Patumraj, S; Siriviriyakul, P, 2004)
"The present experiment was designed to investigate the role of peripheral dopamine D1-like receptors and to evaluate the prophylactic effect of zelandopam, a dopamine D1-like receptor agonist, on puromycin aminonucleoside (PA)-induced nephrosis in rats."3.73Effect of zelandopam, a dopamine D1-like receptor agonist, in puromycin aminonucleoside nephrosis rats. ( Aoki, M; Tanaka, A; Yatsu, T, 2005)
"A large subset of patients with chronic renal failure showed PBMC resistance to cyclosporine and prednisolone."1.30Immunosuppressant pharmacodynamics on lymphocytes from healthy subjects and patients with chronic renal failure, nephrosis, and psoriasis: possible implications for individual therapeutic efficacy. ( Hirano, T; Hirata, M; Ichikawa, M; Koga, M; Kozaki, K; Kozaki, M; Matsuno, N; Nagao, T; Oh-i, T; Oka, K; Takeuchi, H; Umezawa, Y; Yoshida, M, 1997)

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-199037 (80.43)18.7374
1990's3 (6.52)18.2507
2000's4 (8.70)29.6817
2010's2 (4.35)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yamada, N1
Yoshida, Y1
Ohsawa, T1
Takahara, M1
Morino, S1
Yamamoto, O1
Liu, X1
Li, W1
Liang, Z1
Zhang, X1
Guo, Y1
Gong, T1
Zhang, Z1
ARNEIL, GC2
SHERER, MG1
SIEFRING, BN1
FINKEL, KC1
ISRAELS, S1
FONTANA, VJ2
KUTTNER, AG2
LARON, Z1
YONIS, Z1
GEIFMAN, M1
GARTY, R1
CSORDAS, J1
KYRIAKOPULA, I1
ROHWEDDER, HJ1
CHANDRA, RK1
MAKASHIR, PD1
BHAKOO, ON1
WALIA, BN1
ANIBALDI, A1
BOSCHERINI, B1
PATANE, E1
PEDULLA, T1
PETRANYI, G2
SIEGENTHALER, W1
SIEGENTHALER, G1
BONER, A1
SAXENA, KM1
CRAWFORD, JD1
HERTL, M1
Futrakul, N1
Panichakul, T1
Butthep, P1
Futrakul, P1
Jetanalin, P1
Patumraj, S1
Siriviriyakul, P1
Yatsu, T1
Aoki, M1
Tanaka, A1
Hirano, T2
Fukushima, H1
Sasaki, Y1
Yoshikawa, N1
Yoshida, M2
Oka, K2
Johnston, JA1
Manson, G1
Meyer, R1
Whitten, C1
Guillemette, ME1
Lam, CN1
Leövey, A1
Hohenwallner, W1
Ogihara, T1
Inagaki, Y1
Nagata, S1
Kiryu, Y1
Miyake, S1
Shimizu, K1
Imai, H1
Kodama, T1
Yasuda, T1
Nakamoto, Y1
Miura, AB1
Takeuchi, H1
Kozaki, K1
Matsuno, N1
Nagao, T1
Kozaki, M1
Ichikawa, M1
Umezawa, Y1
Hirata, M1
Oh-i, T1
Koga, M1
Zhou, X1
Loke, KY1
Pillai, CC1
How, HK1
Yap, HK1
Lee, KO1
Shinozaki, Y1
Ito, M1
Fukunaga, T1
Nosaka, Y1
Miller, PF1
Bowmer, CJ1
Wheeldon, J1
Brocklebank, JT1
Baron, S1
Raux Demay, MC1
Vasmant, D1
Bensman, A1
Cameron, JS1
Glasgow, EF1
Ogg, CS1
White, RH1
Kobayashi, A1
Ohbe, Y1
Lines, DR1
Ono, J1
Gács, G2
Berend, K1
Takahashi, S1
Kun, E1
Czirbesz, Z1
Pyrig, LA1
Linneweh, F1
Singh, M1
Nagasaka, M1
Boyd, DH1
Rawles, JM1
Takatsu, T1
Bihari, M1
Grossman, BJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Study of Pharmacokinetic Variability of Glucocorticoids in Children[NCT02252237]146 participants (Actual)Observational2014-12-03Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for prednisolone and Nephrosis

ArticleYear
[TREATMENT OF KIDNEY DISEASES, CARDIAC AND VASCULAR DISORDERS AS WELL AS COLLAGENOSES WITH CORTISONES].
    Die Therapiewoche, 1964, Volume: 14

    Topics: Adams-Stokes Syndrome; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Arthritis, Rheumatoid;

1964

Trials

2 trials available for prednisolone and Nephrosis

ArticleYear
Ganoderma lucidum suppresses endothelial cell cytotoxicity and proteinuria in persistent proteinuric focal segmental glomerulosclerosis (FSGS) nephrosis.
    Clinical hemorheology and microcirculation, 2004, Volume: 31, Issue:4

    Topics: Anti-Inflammatory Agents; Cell Death; Cyclophosphamide; Cytokines; Drug Therapy, Combination; Endoth

2004
IGFs and IGF-binding proteins in short children with steroid-dependent nephrotic syndrome on chronic glucocorticoids: changes with 1 year exogenous GH.
    European journal of endocrinology, 2001, Volume: 144, Issue:3

    Topics: Adolescent; Blotting, Western; Body Height; Bone Development; Carrier Proteins; Child; Cholesterol;

2001

Other Studies

43 other studies available for prednisolone and Nephrosis

ArticleYear
A case of cutaneous protothecosis successfully treated with local thermal therapy as an adjunct to itraconazole therapy in an immunocompromised host.
    Medical mycology, 2010, Volume: 48, Issue:4

    Topics: Aged; Antifungal Agents; Combined Modality Therapy; Hand; Hot Temperature; Humans; Immunocompromised

2010
Prednisolone-glucose derivative conjugate: synthesis, biodistribution and pharmacodynamics evaluation.
    Archiv der Pharmazie, 2012, Volume: 345, Issue:12

    Topics: Animals; Drug Delivery Systems; Drug Stability; Glucocorticoids; Glucose; Kidney; Male; Molecular St

2012
Treatment of nephrosis with prednisolone.
    Lancet (London, England), 1956, Apr-14, Volume: 270, Issue:6920

    Topics: Child; Humans; Infant; Nephrosis; Prednisolone; Steroids

1956
Effect of prednisone and prednisolone on thyroid function, with special reference to thyroxine-binding protein in nephrosis.
    The Journal of clinical endocrinology and metabolism, 1956, Volume: 16, Issue:5

    Topics: Blood Proteins; Humans; Iodine; Iodine Radioisotopes; Nephrosis; Prednisolone; Prednisone; Radioisot

1956
Paradione nephrosis.
    The Journal-lancet, 1959, Volume: 79, Issue:6

    Topics: Anticonvulsants; Child; Infant; Nephrosis; Nephrotic Syndrome; Oxazoles; Prednisolone

1959
Treatment of nephrosis with methylprednisolone.
    New York state journal of medicine, 1960, Dec-01, Volume: 60

    Topics: Humans; Methylprednisolone; Nephrosis; Prednisolone

1960
Use of 6-methylprednisolone (Medrol) in the treatment of nephrosis in children.
    Helvetica paediatrica acta, 1961, Volume: 16

    Topics: Child; Humans; Infant; Methylprednisolone; Nephrosis; Nephrotic Syndrome; Prednisolone

1961
Paperchromatographic analysis of the urinary steroids in nephrotic children treated with prednisolone.
    Acta paediatrica Academiae Scientiarum Hungaricae, 1962, Volume: 3

    Topics: Child; Chromatography; Humans; Infant; Nephrosis; Prednisolone; Steroids

1962
Studies on experimental nephrosis produced by isosensitization in rats.
    The Journal of pediatrics, 1962, Volume: 60

    Topics: Animals; Antigen-Antibody Reactions; Histamine; Histamine H1 Antagonists; Nephrosis; Prednisolone; R

1962
[Observations on the use of 16-methyleneprednisolone in pediatrics].
    Medizinische Monatsschrift, 1963, Volume: 17

    Topics: Adrenal Cortex Hormones; Arthritis; Arthritis, Rheumatoid; Asthma; Leukemia; Nephrosis; Pediatrics;

1963
SERUM AMYLASE ACTIVITY IN CHILDREN ON PROLONGED PREDNISOLONE THERAPY.
    Indian journal of pediatrics, 1963, Volume: 30

    Topics: Adolescent; Amylases; Blood Chemical Analysis; Child; Clinical Enzyme Tests; Humans; Nephrosis; Panc

1963
FATTY LIVER IN PREDNISOLONE TREATED NEPHROTIC CHILDREN.
    The Journal of tropical pediatrics and African child health, 1963, Volume: 9

    Topics: Adolescent; Biopsy; Blood Proteins; Child; Fatty Liver; Humans; Infant; Nephrosis; Prednisolone; Pro

1963
[EFFECTS OF HYDROCHLOROTHIAZIDE ASSOCIATED WITH ALDOSTERONE IN THE THERAPY OF NEPHROTIC EDEMA. I. CLINICAL RESULTS AND STUDY OF WATER AND SALT METABOLISM IN 3 CASES].
    Il Progresso medico, 1963, Sep-15, Volume: 19

    Topics: Adrenocorticotropic Hormone; Aldosterone; Child; Edema; Glomerulonephritis; Humans; Hydrochlorothiaz

1963
[TREATMENT OF LUPUS-NEPHROPATHIES WITH 6-MERCAPTOPURINE].
    Orvosi hetilap, 1964, Jan-19, Volume: 105

    Topics: Albuminuria; Chloroquine; Diuretics; Edema; Glomerulonephritis; Humans; Lupus Erythematosus, Discoid

1964
THE TREATMENT OF NEPHROSIS.
    The New England journal of medicine, 1965, Mar-11, Volume: 272

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Antihypertensive Agents; Child; Cortisone; Dex

1965
[Inhibitory effect of ACTH and cortisone derivatives on diuretics. Observations in nephritis-nephrosis].
    Munchener medizinische Wochenschrift (1950), 1960, May-27, Volume: 102

    Topics: Adrenocorticotropic Hormone; Chlorothiazide; Cortisone; Diuretics; Kidney Diseases; Nephritis; Nephr

1960
Effect of zelandopam, a dopamine D1-like receptor agonist, in puromycin aminonucleoside nephrosis rats.
    European journal of pharmacology, 2005, Mar-07, Volume: 510, Issue:1-2

    Topics: Animals; Dose-Response Relationship, Drug; Female; Nephrosis; Prednisolone; Proteinuria; Puromycin A

2005
Bacterial superantigen TSST-1 attenuates suppressive efficacy of glucocorticoids and calcineurin inhibitors against blastogenesis of peripheral blood mononuclear cells from patients with antineutrophil cytoplasmic antibody-associated vasculitis and nephro
    International immunopharmacology, 2006, Volume: 6, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Antineutrophil Cytoplasmic; Bacterial Toxins; Calcineuri

2006
Intermittent steroid therapy in nephrosis.
    American journal of diseases of children (1960), 1967, Volume: 114, Issue:3

    Topics: Adolescent; Calcium; Child; Child, Preschool; Female; Humans; Male; Nephrosis; Nitrogen; Prednisolon

1967
Long-term assessment of steroid treatment of idiopathic childhood nephrosis.
    American heart journal, 1967, Volume: 74, Issue:4

    Topics: Child; Humans; Nephrosis; Prednisolone; Retrospective Studies; Steroids

1967
Steroid treatment of lupus nephropathy: results of 60 cases.
    Acta medica Academiae Scientiarum Hungaricae, 1967, Volume: 23, Issue:3

    Topics: Adrenal Cortex Hormones; Autoimmune Diseases; Glomerulonephritis; Humans; Lupus Erythematosus, Syste

1967
[Effect of corticoids on the activity of glucose-6-phosphate dehydrogenase in erythrocytes].
    Clinica chimica acta; international journal of clinical chemistry, 1967, Volume: 16, Issue:3

    Topics: Adolescent; Child; Child, Preschool; Cortisone; Erythrocytes; Female; Glucosephosphate Dehydrogenase

1967
Combination chemotherapy in retroperitoneal poorly differentiated myxoid liposarcoma: a report of a case.
    Japanese journal of medicine, 1983, Volume: 22, Issue:1

    Topics: Antineoplastic Agents; Constriction, Pathologic; Cyclophosphamide; Dactinomycin; Diabetes Mellitus;

1983
Inverse relationship between serum cholinesterase activity and the administration of cyclophosphamide: an index of cyclophosphamide therapy.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1994, Volume: 9, Issue:9

    Topics: Adolescent; Adult; Aged; Anticoagulants; Biomarkers; Cholinesterases; Cyclophosphamide; Drug Monitor

1994
Immunosuppressant pharmacodynamics on lymphocytes from healthy subjects and patients with chronic renal failure, nephrosis, and psoriasis: possible implications for individual therapeutic efficacy.
    Clinical pharmacology and therapeutics, 1997, Volume: 62, Issue:6

    Topics: Adult; Anti-Inflammatory Agents; Cyclosporine; Female; Humans; Immunosuppressive Agents; Kidney Fail

1997
[A case of acute myeloblastic leukemia after immunosuppresive therapy for nephrosis (author's transl)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1979, Volume: 20, Issue:6

    Topics: Adult; Cyclophosphamide; Female; Humans; Immunosuppression Therapy; Leukemia, Myeloid, Acute; Nephro

1979
Effects of prolonged use of adrenocortical hormones on the tonsils in children.
    The Kumamoto medical journal, 1975, Mar-31, Volume: 28, Issue:1

    Topics: Adolescent; Betamethasone; Child; Child, Preschool; Humans; Male; Nephrosis; Palatine Tonsil; Predni

1975
Pharmacokinetics of prednisolone in children with nephrosis.
    Archives of disease in childhood, 1990, Volume: 65, Issue:2

    Topics: Adolescent; Child; Child, Preschool; Female; Half-Life; Humans; Injections, Intravenous; Liver; Male

1990
[Pharmacokinetics of prednisolone in children. Study of a correlation with tolerability and therapeutic effect in nephrosis].
    Presse medicale (Paris, France : 1983), 1988, Apr-09, Volume: 17, Issue:13

    Topics: Child; Child, Preschool; Drug Resistance; Female; Humans; Male; Nephrosis; Prednisolone; Prospective

1988
Membranoproliferative glomerulonephritis and persistent hypocomplementaemia.
    British medical journal, 1970, Oct-03, Volume: 4, Issue:5726

    Topics: Adolescent; Adult; Azathioprine; Beta-Globulins; Blood Protein Disorders; Child; Child, Preschool; C

1970
Nephrosis, cyclophosphamide therapy, and severe systemic varicella recovery with massive doses of intravenous human immune serum globulin.
    Monatsschrift fur Kinderheilkunde, 1973, Volume: 121, Issue:2

    Topics: Chickenpox; Child; Cross Infection; Cyclophosphamide; Encephalitis; Female; gamma-Globulins; Hemorrh

1973
Nephrotic syndrome and nephroblastoma. Report of a case.
    The Journal of pediatrics, 1968, Volume: 72, Issue:2

    Topics: Azathioprine; Child, Preschool; Edema; Humans; Kidney Neoplasms; Male; Nephrosis; Prednisolone; Urog

1968
[Treatment of chronic glomerulonephritis with steroids and immunosuppressive agents].
    Nihon rinsho. Japanese journal of clinical medicine, 1974, Volume: 32, Issue:10

    Topics: Adolescent; Adult; Chronic Disease; Female; Glomerulonephritis; Humans; Immunosuppressive Agents; Ma

1974
Plasma glucose, insulin and free fatty acids during long-term corticosteroid treatment in children.
    Acta endocrinologica, 1974, Volume: 77, Issue:4

    Topics: Adolescent; Arginine; Arthritis, Juvenile; Blood Glucose; Child; Child, Preschool; Fatty Acids, None

1974
[Experimental steroid nephropathy. 5. Mechanism of development. 2. Serially observed morphological changes].
    Nihon Jinzo Gakkai shi, 1972, Volume: 14, Issue:2

    Topics: Animals; Basement Membrane; Female; Fluorescent Antibody Technique; Kidney; Kidney Glomerulus; Micro

1972
Growth hormone secretion in children during corticosteroid treatment. Responses to arginine.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1973, Volume: 5, Issue:2

    Topics: Adolescent; Arginine; Arthritis, Rheumatoid; Blood Glucose; Child; Child, Preschool; Growth Hormone;

1973
[Steroid therapy of the nephrotic form of chronic glomerulonephritis].
    Vrachebnoe delo, 1973, Volume: 1

    Topics: Adolescent; Adult; Chronic Disease; Dexamethasone; Female; Glomerulonephritis; Humans; Male; Nephros

1973
[Therapy of the nephrotic syndrome in children].
    Minerva medica, 1973, Oct-27, Volume: 64, Issue:76

    Topics: Adrenal Cortex Hormones; Azathioprine; Child; Child, Preschool; Humans; Immunosuppressive Agents; Ne

1973
Thromboembolic complications in childhood nephrosis associated with prednisiolone and hydrochlorothiazide therapy.
    Journal of the Indian Medical Association, 1969, Nov-01, Volume: 53, Issue:9

    Topics: Child; Female; Humans; Hydrochlorothiazide; Iatrogenic Disease; Intracranial Embolism and Thrombosis

1969
[Determination of the therapeutic effects and prognosis in internal diseases by computer--with reference to nephrosis].
    Naika. Internal medicine, 1967, Volume: 20, Issue:1

    Topics: Adolescent; Adult; Child; Computers; Female; Humans; Male; Nephrosis; Prednisolone; Prognosis

1967
Arterial calcification in association with a connective tissue disorder.
    Annals of the rheumatic diseases, 1968, Volume: 27, Issue:4

    Topics: Adolescent; Arteries; Calcinosis; Colitis, Ulcerative; Collagen Diseases; Humans; Joint Diseases; Ma

1968
[Panel discussion. Edema. Edema in pediatrics].
    Nihon Ishikai zasshi. Journal of the Japan Medical Association, 1968, Feb-01, Volume: 59, Issue:3

    Topics: Adolescent; Child; Child, Preschool; Cyclophosphamide; Edema; Humans; Mercaptopurine; Nephrosis; Nep

1968
Posterior subcapsular cataracts. Related to long-term corticosteroid treatment in children.
    American journal of diseases of children (1960), 1968, Volume: 116, Issue:6

    Topics: Adolescent; Arthritis, Juvenile; Cataract; Child; Child, Preschool; Chloroquine; Colitis, Ulcerative

1968