Page last updated: 2024-11-06

prednisolone and Myeloproliferative Disorders

prednisolone has been researched along with Myeloproliferative Disorders in 13 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Myeloproliferative Disorders: Conditions which cause proliferation of hemopoietically active tissue or of tissue which has embryonic hemopoietic potential. They all involve dysregulation of multipotent MYELOID PROGENITOR CELLS, most often caused by a mutation in the JAK2 PROTEIN TYROSINE KINASE.

Research Excerpts

ExcerptRelevanceReference
" The patient was treated with prednisolone (0·5-1 mg/kg/day) for more than 20 weeks under the impression of hypereosinophilic syndrome, but without improvement of leucocytosis and eosinophilia."7.76A case of myeloid neoplasm associated with eosinophilia and KIAA1509-PDGFRβ responsive to combination treatment with imatinib mesylate and prednisolone. ( Gau, JP; Hsiao, LT; Liu, CY; Pai, JT; Teng, HW; Tzeng, CH; Wang, JR; Yen, CC, 2010)
"We encountered a male patient with marked basophilia and eosinophilia complicated by anemia, thrombocytopenia, myelofibrosis, and hyperhistaminemia."7.69A patient with basophilic-eosinophilic myeloproliferative disorder showing monosomy 7 and hyperhistaminemia. ( Hayashi, Y; Imanaka, F; Shindo, H; Takimoto, Y, 1997)
" The patient was treated with prednisolone (0·5-1 mg/kg/day) for more than 20 weeks under the impression of hypereosinophilic syndrome, but without improvement of leucocytosis and eosinophilia."3.76A case of myeloid neoplasm associated with eosinophilia and KIAA1509-PDGFRβ responsive to combination treatment with imatinib mesylate and prednisolone. ( Gau, JP; Hsiao, LT; Liu, CY; Pai, JT; Teng, HW; Tzeng, CH; Wang, JR; Yen, CC, 2010)
"We encountered a male patient with marked basophilia and eosinophilia complicated by anemia, thrombocytopenia, myelofibrosis, and hyperhistaminemia."3.69A patient with basophilic-eosinophilic myeloproliferative disorder showing monosomy 7 and hyperhistaminemia. ( Hayashi, Y; Imanaka, F; Shindo, H; Takimoto, Y, 1997)
"Prednisolone was added if there was no response after 3 months in cohort 1 and based on up-front randomization in cohort 2 if there was no response at 3 or 6 months."2.84Pomalidomide in myeloproliferative neoplasm-associated myelofibrosis. ( Benner, A; Blau, IW; Döhner, H; Döhner, K; Gattermann, N; Grießhammer, M; Hebart, H; Heidel, FH; Hochhaus, A; Jost, E; Kreipe, H; Platzbecker, U; Reiter, A; Schafhausen, P; Schlenk, RF; Stegelmann, F; Teleanu, V; Verbeek, W; Waller, C; Werner, M, 2017)
"The clinical course suggests that the pneumonitis was induced by hydroxycarbamide."2.58A 66-year-old man with hydroxycarbamide induced pneumonitis. ( Derichs, C; Klooster, P; Vlasveld, LT, 2018)
"Oral prednisolone treatment improved the pulmonary nodular lesion, the abnormal laboratory data, and the uveitis."1.31[A case of pulmonary inflammatory pseudotumor with hypergammaglobulinemia, elevated ANA, and uveitis]. ( Gejyo, F; Kaizu, C; Kuwabara, K; Moriyama, H; Saito, Y; Suzuki, E; Takada, T; Terada, M, 2001)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's3 (23.08)18.2507
2000's3 (23.08)29.6817
2010's6 (46.15)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Derichs, C1
Klooster, P1
Vlasveld, LT1
Olivieri, A1
Cimminiello, M1
Corradini, P1
Mordini, N1
Fedele, R1
Selleri, C1
Onida, F1
Patriarca, F1
Pavone, E1
Svegliati, S1
Gabrielli, A1
Bresciani, P1
Nuccorini, R1
Pascale, S1
Coluzzi, S1
Pane, F1
Poloni, A1
Olivieri, J1
Leoni, P1
Bacigalupo, A1
Koudoukpo, C1
Jachiet, M1
Zini, JM1
Andreoli, A1
Pinquier, L1
Rybojad, M1
Bosset, D1
de Masson, A1
Bagot, M1
Lebbé, C1
Bouaziz, JD1
Schlenk, RF1
Stegelmann, F1
Reiter, A1
Jost, E1
Gattermann, N1
Hebart, H1
Waller, C1
Hochhaus, A1
Platzbecker, U1
Schafhausen, P1
Blau, IW1
Verbeek, W1
Heidel, FH1
Werner, M1
Kreipe, H1
Teleanu, V1
Benner, A1
Döhner, H1
Grießhammer, M1
Döhner, K1
Wang, JR1
Yen, CC1
Gau, JP1
Hsiao, LT1
Liu, CY1
Pai, JT1
Tzeng, CH1
Teng, HW1
Sawada, T1
Adachi, Y1
Ishii, Y1
Yasui, H1
Arimura, Y1
Endo, T1
ROTHERMUNDT, A1
Miyazawa, K1
Kakazu, N1
Ohyashiki, K1
Shenoy, RD1
Bhat, KG1
Kamath, N1
Kumble, Y1
Chandran, G1
Ahern, MJ1
Seshadri, P1
Coghlan, D1
Takimoto, Y1
Imanaka, F1
Hayashi, Y1
Shindo, H1
Hagiwara, S1
Yuo, A1
Miwa, A1
Takezako, N1
Hirano, N1
Togawa, A1
Kaizu, C1
Takada, T1
Moriyama, H1
Terada, M1
Suzuki, E1
Gejyo, F1
Kuwabara, K1
Saito, Y1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Multi-Center Phase II Study With Pomalidomide in Patients With Myeloproliferative Neoplasms in Fibrotic Stage[NCT00949364]Phase 2103 participants (Actual)Interventional2009-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for prednisolone and Myeloproliferative Disorders

ArticleYear
A 66-year-old man with hydroxycarbamide induced pneumonitis.
    The Netherlands journal of medicine, 2018, Volume: 76, Issue:6

    Topics: Administration, Oral; Aged; Disease Progression; Dose-Response Relationship, Drug; Drug Administrati

2018

Trials

2 trials available for prednisolone and Myeloproliferative Disorders

ArticleYear
Long-term outcome and prospective validation of NIH response criteria in 39 patients receiving imatinib for steroid-refractory chronic GVHD.
    Blood, 2013, Dec-12, Volume: 122, Issue:25

    Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Autoantibodies; Benzamides; Chronic Disease; Disease-F

2013
Pomalidomide in myeloproliferative neoplasm-associated myelofibrosis.
    Leukemia, 2017, Volume: 31, Issue:4

    Topics: Aged; Aged, 80 and over; Alleles; Biomarkers; Chromosome Banding; Female; Humans; Immunologic Factor

2017

Other Studies

10 other studies available for prednisolone and Myeloproliferative Disorders

ArticleYear
[Urticarial vasculitis associated with essential thrombocythaemia progressing to myelofibrosis].
    Annales de dermatologie et de venereologie, 2014, Volume: 141, Issue:12

    Topics: Bone Marrow; Drug Therapy, Combination; Fatal Outcome; Humans; Janus Kinase 2; Male; Middle Aged; Mu

2014
A case of myeloid neoplasm associated with eosinophilia and KIAA1509-PDGFRβ responsive to combination treatment with imatinib mesylate and prednisolone.
    Journal of clinical pharmacy and therapeutics, 2010, Volume: 35, Issue:6

    Topics: Adult; Antineoplastic Agents, Hormonal; Benzamides; Drug Therapy, Combination; Eosinophilia; Eosinop

2010
Esophageal lesions in myeloproliferative neoplasms.
    Endoscopy, 2012, Volume: 44 Suppl 2 UCTN

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cyclophosphamide; Esophageal Neopl

2012
[MASSIVE CELL INFILTRATION OF THE PULMONARY PARENCHYMA IN ALEUKEMIC CHRONIC MYELOSIS].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1964, Jul-01, Volume: 19

    Topics: Humans; Leukemia; Leukemia, Myeloid; Lung; Lung Diseases; Myeloproliferative Disorders; Pathology; P

1964
Clinical features of hypereosinophilic syndrome: FIP1L1-PDGFRA fusion gene-positive disease is a distinct clinical entity with myeloproliferative features and a poor response to corticosteroid.
    International journal of hematology, 2007, Volume: 85, Issue:1

    Topics: Adrenal Cortex Hormones; Adult; Aged; Bone Marrow; Eosinophilia; Female; Fibrosis; Humans; Hypereosi

2007
Transient myeloproliferative disorder and eosinophilic pericardial effusion in a down syndrome neonate.
    Pediatric hematology and oncology, 2008, Volume: 25, Issue:2

    Topics: Antineoplastic Agents, Hormonal; Down Syndrome; Eosinophils; Humans; Infant, Newborn; Male; Myelopro

2008
Rheumatic manifestations of the myelodysplastic syndromes: a comparative study.
    Australian and New Zealand journal of medicine, 1996, Volume: 26, Issue:5

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents; Diagnosis, Differential; Female; Humans; Male; My

1996
A patient with basophilic-eosinophilic myeloproliferative disorder showing monosomy 7 and hyperhistaminemia.
    Acta haematologica, 1997, Volume: 98, Issue:1

    Topics: Aged; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Arabinonucleotides; Basophils; Chromos

1997
A rare atypical myeloproliferative-disorder-like hemopathy with marked dysplasia, peripheral dominant myeloblast proliferation and extramedullary hematopoiesis was converted into typical acute myeloid leukemia with an interval of complete hematological re
    International journal of hematology, 1998, Volume: 67, Issue:4

    Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin

1998
[A case of pulmonary inflammatory pseudotumor with hypergammaglobulinemia, elevated ANA, and uveitis].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2001, Volume: 39, Issue:8

    Topics: Administration, Oral; Antibodies, Antinuclear; Chronic Disease; Glaucoma; Humans; Hypergammaglobulin

2001