Page last updated: 2024-11-06

prednisolone and Muscle Weakness

prednisolone has been researched along with Muscle Weakness in 79 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Muscle Weakness: A vague complaint of debility, fatigue, or exhaustion attributable to weakness of various muscles. The weakness can be characterized as subacute or chronic, often progressive, and is a manifestation of many muscle and neuromuscular diseases. (From Wyngaarden et al., Cecil Textbook of Medicine, 19th ed, p2251)

Research Excerpts

ExcerptRelevanceReference
"An 11-year-old girl with a calpain-3 gene (CAPN-3) mutation and eosinophilic myositis on muscle biopsy had high serum CK levels and eosinophil counts which showed spontaneous fluctuations."7.75Eosinophilic myositis in calpainopathy: could immunosuppression of the eosinophilic myositis alter the early natural course of the dystrophic disease? ( Dincer, P; Gundesli, H; Oflazer, PS; Sabuncu, T; Zorludemir, S, 2009)
" He visited a rheumatologist in an outpatient clinic, and according to proximal muscle weakness and heliotrope rash (based on the rheumatologist's notes) with the impression of dermatomyositis, prednisolone and azathioprine were prescribed for him that did not improve his clinical status and he was gradually wheelchair dependent."4.12Proximal muscle weakness as the sole manifestation of Cushing's disease, misdiagnosed as dermatomyositis: a case report. ( Jeddi, M; Shams, M, 2022)
" Ten and 15 days respectively after initiation of prednisolone treatment both patients experienced exacerbation of sensory symptoms and emerging of muscle weakness."3.81Pure sensory chronic inflammatory polyneuropathy: rapid deterioration after steroid treatment. ( Chroni, E; Gavanozi, E; Papathanasopoulos, P; Polychronopoulos, P; Veltsista, D; Vlachou, T, 2015)
"An 11-year-old girl with a calpain-3 gene (CAPN-3) mutation and eosinophilic myositis on muscle biopsy had high serum CK levels and eosinophil counts which showed spontaneous fluctuations."3.75Eosinophilic myositis in calpainopathy: could immunosuppression of the eosinophilic myositis alter the early natural course of the dystrophic disease? ( Dincer, P; Gundesli, H; Oflazer, PS; Sabuncu, T; Zorludemir, S, 2009)
"Prednisolone treatment significantly improved her myositis."1.56Drop Head Syndrome as a Rare Complication in Mixed Connective Tissue Disease. ( Akagi, M; Endo, Y; Fukui, S; Hara, K; Hashisako, M; Ichinose, K; Igawa, T; Iwamoto, N; Kawakami, A; Kawashiri, SY; Koga, T; Nakamura, H; Niino, D; Origuchi, T; Shimizu, T; Takatani, A; Tamai, M; Tsuji, S; Umeda, M, 2020)
"Excessive weight gain is a potential risk."1.51Twice-weekly glucocorticosteroids in infants and young boys with Duchenne muscular dystrophy. ( Alfano, LN; Anand, P; Connolly, AM; Cradock, MM; Finkel, RS; Flanigan, KM; Florence, JM; Golumbek, PT; Iannaccone, ST; Johnson, LB; Kuntz, NL; Lowes, LP; McDonald, CM; Mendell, JR; Nelson, LL; Nicorici, A; Siener, CA; Zaidman, CM, 2019)
"Its presentation with interstitial lung disease alters its prognosis."1.51Antisynthetase syndrome presenting as interstitial lung disease: a case report. ( Badshah, A; Haider, I; Humayun, M; Pervez, S, 2019)
"A 66-year-old woman with a history of interstitial lung disease presented with a 3-month history of dropped head syndrome (DHS), followed by camptocormia and extremity weakness."1.48Dropped Head Syndrome and the Presence of Rimmed Vacuoles in a Muscle Biopsy in Scleroderma-polymyositis Overlap Syndrome Associated with Anti-Ku Antibody. ( Higuchi, I; Jonosono, M; Mitsuyo, K; Yoshida, M; Yoshida, T, 2018)
"In contrast, cholecystitis is a rare complication."1.48Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss Syndrome) Complicated by Perforation of the Small Intestine and Cholecystitis. ( Inomoto, C; Mizuma, A; Moriya, Y; Nakamura, N; Nakayama, T; Ohnuki, Y; Takizawa, S; Uda, S; Yamamoto, S; Yutani, S, 2018)
"Dermatomyositis is a humoral-mediated inflammatory myopathy with symmetrical proximal muscle weakness and dermatological manifestations such as Gottron's papules, heliotrope rash, periungual abnormalities, and flagellate erythema."1.48Erythroderma and extensive poikiloderma - a rare initial presentation of dermatomyositis: a case report. ( Gunasekera, CN; Herath, HMMTB; Janappriya, GHCC; Keragala, BSDP; Kulatunga, A; Pahalagamage, SP, 2018)
"Investigations revealed interstitial lung disease, inflammatory myopathy and an immunology profile consistent with PL-12 antisynthetase syndrome."1.48Interstitial lung disease and inflammatory myopathy in antisynthetase syndrome with PL-12 antibody. ( Jubber, A; Taylor, J; Tripathi, M, 2018)
"Polymyositis is an inflammatory myopathy which, like SCD, may present with myalgia but is usually associated with proximal muscle weakness."1.42Juvenile polymyositis with unremitting pain and progressive loss of motor and bulbar function on a background of sickle cell disease. ( Bali, S; D'Cruz, D; Inusa, BP; Lazaro, M, 2015)
"Bell's palsy is a non-life threatening disorder with important functional and psychosocial effects."1.39Medium term outcome in Bell's palsy in children. ( Babl, FE; Doyle, J; Keenan, P; Mc Kay, M; McNamara, R, 2013)
"Diagnosis of Becker muscular dystrophy (BMD) was confirmed by genetic testing."1.37Unusual presentation as an adult onset painful myopathy in a Thai patient with Becker muscular dystrophy. ( Pithukpakorn, M, 2011)
"Eosinophilia has been reported previously in patients with Calpainopathy and Becker Muscular Dystrophy and might be an early, but transient feature of a wider range of muscular dystrophies."1.35Eosinophilic myositis as presenting symptom in gamma-sarcoglycanopathy. ( Baumeister, SK; Dekomien, G; Lochmüller, H; Milić-Rasić, V; Todorovic, S; Walter, MC, 2009)
"The patient was diagnosed with breast carcinoma 4 months after initial presentation and underwent resective surgery, radiotherapy, and hormonotherapy."1.35Steroid-responsive paraneoplastic demyelinating neuropathy and myelopathy associated with breast carcinoma. ( Abbott, RJ; Qaddoura, B; Rajabally, YA, 2008)
"Generally, sarcoidosis is identified clinically in patients with foggy vision or mediastinal lymphadenopathy, but muscular weakness may be an infrequently observed initial symptom."1.34Sarcoid myositis with muscle weakness as a presenting symptom. ( Goto, D; Ishii, W; Ito, S; Iwanami, K; Mamura, M; Matsumoto, I; Ogishima, H; Sumida, T; Suzuki, T; Tsutsumi, A; Yamada, H, 2007)
"However, Devic's neuromyelitis optica has also been seen in children."1.34Devic's neuromyelitis optica in an infant case. ( Senbil, N; Yavuz Gurer, YK; Yilmaz, D; Yuksel, D, 2007)
" High dosage steroid should be started before there is biopsy confirmation of the disease."1.32[Excessive hyperferritinemia as an indication of a reactive hemophagocytosis syndrome]. ( Brunner, J; Dinser, R; Engel, A, 2003)
"Hypogonadism has been established as a cause of osteoporosis in males, and in this case would explain the occurrence of fractures in the absence of other major risk factors."1.31Osteoporosis with underlying connective tissue disease: an unusual case. ( De Silva, M; Prasad, R, 2002)
" On Day 8, the nerve-evoked peak twitch tensions, tetanic tensions, and fatigability, and the dose-response curves of d-tubocurarine in the tibialis cranialis muscle were measured in vivo and related to muscle mass or expression of AChRs."1.31Prednisolone-induced muscle dysfunction is caused more by atrophy than by altered acetylcholine receptor expression. ( Fink, H; Ibebunjo, C; Khiroya, R; Martyn, J; Shin, YS, 2000)

Research

Studies (79)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (2.53)18.2507
2000's31 (39.24)29.6817
2010's34 (43.04)24.3611
2020's12 (15.19)2.80

Authors

AuthorsStudies
Mekmangkonthong, A1
Amornvit, J1
Numkarunarunrote, N1
Veeravigrom, M1
Khaosut, P1
Kuroda, H1
Yamaguchi, A1
Sugata, S1
Hamada, T1
Moriuchi, R1
Wada, K1
Tamaru, Y1
Kusunoki, R1
Kuwai, T1
Kouno, H1
Kurashige, T1
Torii, T1
Saito, A2
Kuraoka, K1
Kohno, H1
Jeddi, M1
Shams, M1
Loghman, M1
Rahmanian, E1
Alikhani, M1
Saffar, H1
Beikmohamadi Hezaveh, S1
Nekooeian, M1
Shahriarirad, R1
Faezi, ST1
Akagi, M1
Umeda, M1
Hashisako, M1
Hara, K2
Tsuji, S1
Endo, Y1
Takatani, A1
Shimizu, T1
Fukui, S1
Koga, T2
Kawashiri, SY1
Iwamoto, N1
Igawa, T1
Ichinose, K2
Tamai, M1
Nakamura, H1
Origuchi, T1
Niino, D1
Kawakami, A1
Guess, KE1
Harada, Y1
Hill, A1
Ferry, J1
Veerapandiyan, A1
Nagiah, S1
Saranapala, DMM1
Finsterer, J1
Scorza, CA1
Fiorini, AC1
Scorza, FA1
Beck, G1
Yamashita, R1
Saeki, C1
Ogawa, T1
Shimizu, M1
Mochizuki, H2
Cavallasca, JA1
Cousillas, JE1
Takahashi, F1
Sawada, J1
Minoshima, A1
Sakamoto, N1
Ono, T1
Akasaka, K1
Takei, H1
Nishino, I1
Hasebe, N1
Ueda, R1
Imai, K1
Yamamoto, A1
Ioku, T1
Kadoya, M1
Hamanaka, M1
Iida, H1
Hanaoka, H1
Asari, Y1
Ishimori, K1
Kiyokawa, T1
Takakuwa, Y1
Yamasaki, Y1
Yamada, H2
Okazaki, T1
Doi, M1
Ozaki, S1
Yoshida, T1
Yoshida, M1
Mitsuyo, K1
Jonosono, M1
Higuchi, I1
Ohnuki, Y2
Moriya, Y1
Yutani, S1
Mizuma, A1
Nakayama, T1
Uda, S1
Inomoto, C1
Yamamoto, S1
Nakamura, N1
Takizawa, S1
Ojima, Y1
Sawada, K1
Fujii, H1
Shirai, T1
Kagaya, S1
Aoki, S1
Takeuchi, Y1
Ishii, T1
Nagasawa, T1
Herath, HMMTB1
Keragala, BSDP1
Pahalagamage, SP1
Janappriya, GHCC1
Kulatunga, A1
Gunasekera, CN1
Chawla, D1
Mishra, D1
Singh, S1
Juneja, M1
Jubber, A1
Tripathi, M1
Taylor, J1
Connolly, AM2
Zaidman, CM1
Golumbek, PT2
Cradock, MM1
Flanigan, KM1
Kuntz, NL1
Finkel, RS1
McDonald, CM1
Iannaccone, ST1
Anand, P1
Siener, CA1
Florence, JM1
Lowes, LP1
Alfano, LN1
Johnson, LB1
Nicorici, A1
Nelson, LL1
Mendell, JR1
Badshah, A1
Haider, I1
Pervez, S1
Humayun, M1
Steggink, LC1
Hettema, ME1
Delsing, CE1
Janssen, PM1
Murray, JD1
Schill, KE1
Rastogi, N1
Schultz, EJ1
Tran, T1
Raman, SV1
Rafael-Fortney, JA1
Yoshida, S2
Kikuchi, A1
Tateyama, M1
Tano, O1
Nishiyama, A1
Akaishi, T1
Kato, M1
Aoki, M1
Constable, H1
Wood, F1
Jones, K1
Malkan, A1
Cappelen-Smith, C1
Beran, R1
Griffith, N1
Toong, C1
Wang, MX1
Cordato, D1
Vinay, K1
Dogra, S1
Bali, S1
D'Cruz, D1
Lazaro, M1
Inusa, BP1
Chroni, E1
Veltsista, D1
Gavanozi, E1
Vlachou, T1
Polychronopoulos, P1
Papathanasopoulos, P1
Theofilos, D1
Triantafillidou, C1
Zetos, A1
Bisirtzoglou, D1
Konstantinou, F1
Marketos, C1
Politis, G1
Chamarthi, VS1
Chamarthi, S1
Johansson, BE1
Ong, SG1
Ding, HJ1
Lynch, RW1
Soane, T1
Gibson, R1
Pal, S1
Lees, CW1
Anantharajah, A1
Vucic, S1
Tarafdar, S1
Vongsuvanh, R1
Wilcken, N1
Swaminathan, S1
Cekinmez, EK1
Cengiz, N1
Erol, I1
Kizilkiliç, O1
Uslu, Y1
Yoshimoto, M1
Kawaguchi, S1
Takebayashi, T1
Isogai, S1
Nonaka, S1
Kosukegawa, I1
Yamashita, T1
Nishikawa, T1
Kawakami, K1
Kumamoto, T2
Tonooka, S1
Abe, A1
Hayasaka, K1
Okamoto, Y1
Kawano, Y1
Baumeister, SK1
Todorovic, S1
Milić-Rasić, V1
Dekomien, G1
Lochmüller, H1
Walter, MC1
Rajabally, YA1
Qaddoura, B1
Abbott, RJ1
Oflazer, PS1
Gundesli, H1
Zorludemir, S1
Sabuncu, T1
Dincer, P1
Saidha, S1
Mok, TH1
Butler, M1
Keohane, C1
Harrington, H1
Nishigori, K1
Yamamoto, T1
Yokozeki, H1
Migita, K1
Ueda-Nakata, R1
Masuda, T1
Miyashita, T1
Izumi, Y1
Ezaki, H1
Ito, M1
Motomura, M2
Eguchi, K1
Na, SJ1
Kim, SM1
Sunwoo, IN1
Choi, YC1
Franciotta, D1
Zardini, E1
Caporali, R1
Piccolo, L1
Alberici, E1
Romani, A1
Bergamaschi, R1
Marchioni, E1
Ceroni, M1
Piccolo, G1
Li, HZ1
Guo, J1
Lin, H1
Li, Z1
Yamashita, S1
Ueda, A1
Hirahara, T1
Kimura, E1
Hirano, T1
Uchino, M1
Pithukpakorn, M1
Tzermpos, FH1
Cocos, A1
Kleftogiannis, M1
Zarakas, M1
Iatrou, I1
Rehman, HU1
Azzopardi, L1
Quirk, J1
McNamara, R1
Doyle, J1
Mc Kay, M1
Keenan, P1
Babl, FE1
Yoshihara, N1
Okuda, M1
Takano, K1
Wada, T1
Osaka, H1
Hejazi, SM1
Engkasan, JP1
Qomi, MS1
Zach, H1
Cetin, H1
Hilger, E1
Paul, A1
Wuschitz, B1
Jung, R1
Auff, E1
Zimprich, F1
Prasad, R1
De Silva, M1
Johnson, RW1
Williams, FM1
Kazi, S1
Dimachkie, MM1
Reveille, JD1
Inoue, N1
Kunishige, M1
Oshima, Y1
Ohnishi, Y1
Kuroda, Y1
Asano, A1
Yoshino, H1
Matsumoto, T1
Mitsui, T1
Dinser, R1
Brunner, J1
Engel, A1
Paus, S1
Prömse, A1
Schmidt, S1
Klockgether, T1
Yilmaz, O1
Karaduman, A1
Topaloğlu, H1
Yang, YW1
Liu, CH1
Tsai, CH1
Lee, CC1
Jou, SB1
Sharma, BK1
Daga, MK1
Sharma, M1
McIlwain, KL1
DiCarlo, JB1
Miller, SB1
Lim, S1
Rodriguez-Casero, MV1
Shield, LK1
Kornberg, AJ1
de Carvalho, M1
Geraldes, R1
Keeling, RM1
Streif, EM1
Needham, M1
Fabian, V1
Knezevic, W1
Panegyres, P1
Zilko, P1
Mastaglia, FL1
Mashima, T1
Matsuda, A1
Tanaka, K1
Tomita, M1
Shiraishi, H1
Nishizawa, M1
Ishii, W1
Ito, S1
Iwanami, K1
Ogishima, H1
Suzuki, T1
Mamura, M1
Goto, D1
Matsumoto, I1
Tsutsumi, A1
Sumida, T1
Yuksel, D1
Senbil, N1
Yilmaz, D1
Yavuz Gurer, YK1
Kastrup, A1
Gdynia, HJ1
Nägele, T1
Riecker, A1
Ueyama, H1
Johno, M1
Mita, S1
Tsuda, T1
Peris, P1
Font, J1
Grau, JM1
Martínez de Osaba, MJ1
Filella, X1
Muñoz-Gómez, J1
Ryan, MM1
Grattan-Smith, PJ1
Procopis, PG1
Morgan, G1
Ouvrier, RA1
Shin, YS1
Fink, H1
Khiroya, R1
Ibebunjo, C1
Martyn, J1
Vitali, N1
Tondeur, M1
Hermans, P1
Deweerdt, S1
Clumeck, N1
Kamakura, K1
Masaki, T1
Hirata, A1
Nakamura, R1
Motoyoshi, K1
Plumley, SG1
Rubio, R1
Alasfar, S1
Jasin, HE1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase 2 Historically Controlled Trial of Corticosteroids in Young Boys With Duchenne Muscular Dystrophy[NCT02167217]Phase 225 participants (Actual)Interventional2014-04-17Completed
A Randomized Open Label Trial of Spironolactone Versus Prednisolone in Corticosteroid-naïve Boys With DMD[NCT03777319]Phase 12 participants (Actual)Interventional2018-12-05Terminated (stopped due to Inability to recruit participants.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Bayley III Gross Motor Scaled Score (Change From Baseline to 12 Month)

Bayley III Gross Motor Scaled Score measures motor development. This is normed for typically developing children and follow a bell shaped curve. The scale has mean of 10 +/-3 for children at all ages and is bell shaped. Therefore the two standard deviation range is 16 to 4 with higher values indicated better performance. Lower values have been shown to be common in boys with DMD and it this study the baseline average score was 4.2. (NCT02167217)
Timeframe: One year

Interventionunits on a scale (Mean)
Oral Prednisolone4.8

Efficacy: Change in Time to Complete a 100 Meter Timed Test.

The determination of whether spironolactone has similar efficacy to glucocorticoids in improving muscle strength in steroid naïve DMD patients. This will be determined by measuring the time to complete a 100 meter timed test (100M). (NCT03777319)
Timeframe: 6 months

Interventionsec (Number)
Spironolactone-0.6
Prednisolone-5.3

Efficacy: Dynamometry Score

Secondary outcome measures will be Dynamometry score, which is a summation of maximum voluntary isometric contraction test values for knee flexion, knee extension, elbow flexion, and elbow extension (NCT03777319)
Timeframe: 6 months

,
Interventionkg (Number)
Elbow Flexion (Right)-BaselineElbow Flexion (Left)-BaselineElbow Extension (Right)-BaselineElbow Extension (Left)-BaselineKnee Flexion (Right)-BaselineKnee Flexion (Left)-BaselineKnee Extension (Right)-BaselineKnee Extension (Left)-BaselineElbow Flexion (Right)-Month 6Elbow Flexion (Left)-Month 6Elbow Extension (Right)-Month 6Elbow Extension (Left)-Month 6Knee Flexion (Right)-Month 6Knee Flexion (Left)-Month 6Knee Extension (Right)-Month 6Knee Extension (Left)-Month 6
Prednisolone3.64.15.34.13.33.44.85.22.93.44.33.84.13.965.1
Spironolactone00004.12.83.85.93.13.52.42.54.34.17.28.3

Safety Will be Monitored Through Regular Review of Electrolytes.

Electrolytes (Sodium, Potassium, Cloride and Carbon dioxide, mmol/L) will be measured on a monthly basis following initiation of either spironolactone or prednisolone. (NCT03777319)
Timeframe: 6 months

,
Interventionmmol/L (Number)
Sodium-BaselineSodium-Month 1Sodium-Month 2Sodium-Month 3Sodium-Month 4Sodium-Month 5Sodium-Month 6Potassium-BaselinePotassium-Month 1Potassium-Month 2Potassium-Month 3Potassium-Month 4Potassium-Month 5Potassium-Month 6Chloride-BaselineChloride-Month 1Chloride-Month 2Chloride-Month 3Chloride-Month 4Chloride-Month 5Chloride-Month 6CO2-BaselineCO2-Month 1CO2-Month 2CO2-Month 3CO2-Month 4CO2-Month 5CO2-Month 6
Prednisolone1401401391411391391433.844.53.94.64.23.910510510410510510610522242424252626
Spironolactone1421421411421391391404.54.74.24.14.54.54.310310910710310310310129222527282826

Reviews

3 reviews available for prednisolone and Muscle Weakness

ArticleYear
Dengue infection triggered immune mediated necrotizing myopathy in children: a case report and literature review.
    Pediatric rheumatology online journal, 2022, Jun-07, Volume: 20, Issue:1

    Topics: Autoantibodies; Autoimmune Diseases; Child; Dengue; Humans; Male; Muscle Weakness; Muscular Diseases

2022
Advanced gallbladder cancer accompanied with cancer-associated dermatomyositis: A case report and literature review.
    Medicine, 2022, Jul-08, Volume: 101, Issue:27

    Topics: Aged; Deglutition Disorders; Dermatomyositis; Female; Gallbladder Neoplasms; Humans; Muscle Weakness

2022
[Polymyositis associated with HIV immunodeficiency: clinical case and literature review].
    Revue medicale de Bruxelles, 2001, Volume: 22, Issue:3

    Topics: Adult; Anti-Inflammatory Agents; Biopsy; Deglutition Disorders; Diagnosis, Differential; Female; HIV

2001

Trials

3 trials available for prednisolone and Muscle Weakness

ArticleYear
Human immunodeficiency virus-associated polymyositis: a longitudinal study of outcome.
    Arthritis and rheumatism, 2003, Apr-15, Volume: 49, Issue:2

    Topics: Adult; Aged; Anti-HIV Agents; Anti-Inflammatory Agents; Biopsy; CD4-CD8 Ratio; Creatine Kinase; Elec

2003
Prednisolone therapy in Duchenne muscular dystrophy prolongs ambulation and prevents scoliosis.
    European journal of neurology, 2004, Volume: 11, Issue:8

    Topics: Adolescent; Ankle; Anti-Inflammatory Agents; Calcium; Case-Control Studies; Child; Child, Preschool;

2004
Childhood chronic inflammatory demyelinating polyneuropathy: clinical course and long-term outcome.
    Neuromuscular disorders : NMD, 2000, Volume: 10, Issue:6

    Topics: Adolescent; Child; Child, Preschool; Disease Progression; Electromyography; Female; Humans; Immunogl

2000

Other Studies

73 other studies available for prednisolone and Muscle Weakness

ArticleYear
Proximal muscle weakness as the sole manifestation of Cushing's disease, misdiagnosed as dermatomyositis: a case report.
    Journal of medical case reports, 2022, Dec-22, Volume: 16, Issue:1

    Topics: Adult; Cushing Syndrome; Dermatomyositis; Diagnostic Errors; Humans; Iran; Male; Muscle Weakness; Pi

2022
Necrotizing autoimmune myositis following coronavirus disease 2019 infection: a case report.
    Journal of medical case reports, 2022, Dec-27, Volume: 16, Issue:1

    Topics: Aged; Autoimmune Diseases; COVID-19; Humans; Male; Muscle Weakness; Myositis; Prednisolone; SARS-CoV

2022
Drop Head Syndrome as a Rare Complication in Mixed Connective Tissue Disease.
    Internal medicine (Tokyo, Japan), 2020, Mar-01, Volume: 59, Issue:5

    Topics: Antibodies, Antinuclear; Creatine Kinase; Female; Glucocorticoids; Humans; Middle Aged; Mixed Connec

2020
A Toddler With Bilateral Facial Weakness.
    Clinical pediatrics, 2020, Volume: 59, Issue:4-5

    Topics: Diagnosis, Differential; Epstein-Barr Virus Infections; Facial Paralysis; Glucocorticoids; Humans; I

2020
Severe proximal muscle weakness with normal CK as a presenting feature of ANCA-associated vasculitis.
    BMJ case reports, 2020, Jan-21, Volume: 13, Issue:1

    Topics: Aged, 80 and over; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Biopsy; Delayed Diagn

2020
"Initial deterioration" upon intravenous methyl-prednisolon in myasthenia is multifactorial.
    Journal of the neurological sciences, 2020, 05-15, Volume: 412

    Topics: Administration, Intravenous; Humans; Immunosuppressive Agents; Methylprednisolone; Muscle Weakness;

2020
C1-inhibitor Deficiency Induces Myositis-like Symptoms Via the Deposition of the Membrane Attack Complex in the Muscle.
    Internal medicine (Tokyo, Japan), 2020, Sep-01, Volume: 59, Issue:17

    Topics: Adult; Angioedemas, Hereditary; Anti-Inflammatory Agents; Asian People; Complement Membrane Attack C

2020
Numbness and Weakness in a Patient With Systemic Lupus Erythematosus.
    The American journal of medicine, 2021, Volume: 134, Issue:1

    Topics: Electromyography; Female; Glucocorticoids; Humans; Hypesthesia; Lupus Erythematosus, Systemic; Methy

2021
Antimitochondrial Antibody-associated Myopathy with Slowly Progressive Cardiac Dysfunction.
    Internal medicine (Tokyo, Japan), 2021, 04-01, Volume: 60, Issue:7

    Topics: Autoantibodies; Cardiomyopathies; Female; Humans; Middle Aged; Muscle Weakness; Muscular Diseases; P

2021
[Eosinophilic granulomatosis with polyangiitis presenting with Guillain-Barré syndrome-like acute course. A case report].
    Rinsho shinkeigaku = Clinical neurology, 2021, Sep-28, Volume: 61, Issue:9

    Topics: Antibodies, Antineutrophil Cytoplasmic; Churg-Strauss Syndrome; Granulomatosis with Polyangiitis; Gu

2021
Rhabdomyolysis in a Patient with Polyarteritis Nodosa.
    Internal medicine (Tokyo, Japan), 2018, Jan-01, Volume: 57, Issue:1

    Topics: Aged; Anti-Inflammatory Agents; Antibodies, Antineutrophil Cytoplasmic; Antirheumatic Agents; Cyclop

2018
Dropped Head Syndrome and the Presence of Rimmed Vacuoles in a Muscle Biopsy in Scleroderma-polymyositis Overlap Syndrome Associated with Anti-Ku Antibody.
    Internal medicine (Tokyo, Japan), 2018, Mar-15, Volume: 57, Issue:6

    Topics: Aged; Anti-Inflammatory Agents; Autoantibodies; Azathioprine; Female; Head Movements; Humans; Immuno

2018
Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss Syndrome) Complicated by Perforation of the Small Intestine and Cholecystitis.
    Internal medicine (Tokyo, Japan), 2018, Mar-01, Volume: 57, Issue:5

    Topics: Adrenal Cortex Hormones; Aged; Asthma; Cholecystitis; Granulomatosis with Polyangiitis; Humans; Hype

2018
Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis (AAV) Restricted to the Limbs.
    Internal medicine (Tokyo, Japan), 2018, May-01, Volume: 57, Issue:9

    Topics: Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Antibodies, Antineutrophil Cytoplasmic;

2018
Erythroderma and extensive poikiloderma - a rare initial presentation of dermatomyositis: a case report.
    Journal of medical case reports, 2018, Mar-24, Volume: 12, Issue:1

    Topics: Dermatologic Agents; Dermatomyositis; Electromyography; Female; Fever; Humans; Methotrexate; Middle

2018
Longitudinally Extensive Transverse Myelitis.
    Indian journal of pediatrics, 2019, Volume: 86, Issue:1

    Topics: Anti-Inflammatory Agents; Child, Preschool; Fever; Humans; Magnetic Resonance Imaging; Methylprednis

2019
Interstitial lung disease and inflammatory myopathy in antisynthetase syndrome with PL-12 antibody.
    BMJ case reports, 2018, Oct-14, Volume: 2018

    Topics: Aged, 80 and over; Amino Acyl-tRNA Synthetases; Autoantibodies; Deglutition Disorders; Humans; Lung

2018
Twice-weekly glucocorticosteroids in infants and young boys with Duchenne muscular dystrophy.
    Muscle & nerve, 2019, Volume: 59, Issue:6

    Topics: Case-Control Studies; Child, Preschool; Cohort Studies; Disease Progression; Glucocorticoids; Humans

2019
Antisynthetase syndrome presenting as interstitial lung disease: a case report.
    Journal of medical case reports, 2019, Aug-04, Volume: 13, Issue:1

    Topics: Adult; Antibodies, Antinuclear; Autoantibodies; Azathioprine; Creatine Kinase; Diagnosis, Differenti

2019
[A woman with skin abnormalities and muscle weakness].
    Nederlands tijdschrift voor geneeskunde, 2013, Volume: 157, Issue:30

    Topics: Anti-Inflammatory Agents; Dermatomyositis; Female; Humans; Middle Aged; Muscle Weakness; Paresis; Pr

2013
Prednisolone attenuates improvement of cardiac and skeletal contractile function and histopathology by lisinopril and spironolactone in the mdx mouse model of Duchenne muscular dystrophy.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Diuretics; Dystrophin; Female; Gene Expression;

2014
A case of steroid-responsive MADSAM with late appearance of a partial conduction block in the forearm.
    Journal of neurology, 2014, Volume: 261, Issue:4

    Topics: Anti-Inflammatory Agents; Forearm; Hereditary Central Nervous System Demyelinating Diseases; Humans;

2014
The patient with acute muscular weakness.
    Acute medicine, 2014, Volume: 13, Issue:1

    Topics: Acute Disease; Adult; Anti-Inflammatory Agents; Creatine Kinase; Cyclosporine; Dermatomyositis; Diag

2014
Anti-synthetase syndrome associated with anti PL-12 and anti-Signal recognition particle antibodies and a necrotizing auto-immune myositis.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2015, Volume: 22, Issue:2

    Topics: Adult; Anti-Inflammatory Agents; Autoantibodies; Autoimmune Diseases; Cyclophosphamide; Female; Huma

2015
Palmar Gottron papules and Gottron sign.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2015, Volume: 21, Issue:3

    Topics: Dermatomyositis; Erythema; Female; Glucocorticoids; Hand; Humans; Middle Aged; Muscle Weakness; Pred

2015
Juvenile polymyositis with unremitting pain and progressive loss of motor and bulbar function on a background of sickle cell disease.
    BMJ case reports, 2015, Mar-27, Volume: 2015

    Topics: Adolescent; Adrenal Cortex Hormones; Anemia, Sickle Cell; Anti-Inflammatory Agents; Autoimmunity; Az

2015
Pure sensory chronic inflammatory polyneuropathy: rapid deterioration after steroid treatment.
    BMC neurology, 2015, Mar-11, Volume: 15

    Topics: Disease Progression; Female; Glucocorticoids; Humans; Immunoglobulins, Intravenous; Immunologic Fact

2015
A 44-Year-Old Man With Chronic Cough, Weakness, and a Mediastinum Mass.
    Chest, 2015, Volume: 148, Issue:3

    Topics: Adult; Biopsy; Cough; Diagnosis, Differential; Glucocorticoids; Humans; Immunoglobulin G; Male; Medi

2015
Case 3: Acute Onset of Headache, Fever, and Right Arm Weakness in 12-year-old Boy.
    Pediatrics in review, 2015, Volume: 36, Issue:10

    Topics: Anti-Inflammatory Agents; Arm; Child; Diagnosis, Differential; Encephalomyelitis, Acute Disseminated

2015
Patient with statin-associated immune-mediated necrotizing myopathy presenting with subcutaneous edema, persistent bulbar weakness and absent anti-HMGCR.
    International journal of rheumatic diseases, 2017, Volume: 20, Issue:12

    Topics: Aged; Autoantibodies; Azathioprine; Biopsy; Bulbar Palsy, Progressive; Edema; Glucocorticoids; Human

2017
Bilateral lower limb weakness in acute severe ulcerative colitis.
    Lancet (London, England), 2016, Jul-02, Volume: 388, Issue:10039

    Topics: Colitis, Ulcerative; Cyclosporine; Epidural Space; Glucocorticoids; Humans; Immunosuppressive Agents

2016
Prominent subcutaneous oedema as a masquerading symptom of an underlying inflammatory myopathy.
    Internal medicine journal, 2017, Volume: 47, Issue:2

    Topics: Aged; Creatine Kinase; Edema; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Muscle

2017
Unusual cause of acute neurologic deficit in childhood: primary central nervous system vasculitis presenting with basilar arterial occlusion.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2009, Volume: 25, Issue:1

    Topics: Anti-Inflammatory Agents; Arterial Occlusive Diseases; Cerebral Angiography; Child; Diagnosis, Diffe

2009
Morphological changes of the dorsal root ganglion in a patient with herpes zoster seen by magnetic resonance imaging.
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2008, Volume: 13, Issue:4

    Topics: Aged; Anti-Inflammatory Agents; Ganglia, Spinal; Herpes Zoster; Humans; Magnetic Resonance Imaging;

2008
Severe neurotoxicities in a case of Charcot-Marie-Tooth disease type 2 caused by vincristine for acute lymphoblastic leukemia.
    Journal of pediatric hematology/oncology, 2008, Volume: 30, Issue:7

    Topics: Adolescent; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Aspar

2008
Eosinophilic myositis as presenting symptom in gamma-sarcoglycanopathy.
    Neuromuscular disorders : NMD, 2009, Volume: 19, Issue:2

    Topics: Anti-Inflammatory Agents; Biopsy; Disease Progression; DNA Mutational Analysis; Eosinophilia; Female

2009
Steroid-responsive paraneoplastic demyelinating neuropathy and myelopathy associated with breast carcinoma.
    Journal of clinical neuromuscular disease, 2008, Volume: 10, Issue:2

    Topics: Anti-Inflammatory Agents; Breast Neoplasms; Carcinoma; Disease Progression; Female; Humans; Immunogl

2008
Eosinophilic myositis in calpainopathy: could immunosuppression of the eosinophilic myositis alter the early natural course of the dystrophic disease?
    Neuromuscular disorders : NMD, 2009, Volume: 19, Issue:4

    Topics: Azathioprine; Calpain; Child; Creatine Kinase; Disease Progression; Dose-Response Relationship, Drug

2009
Bilateral brachial neuropathy and acute aortic dissection due to giant cell arteritis.
    Journal of neurology, 2009, Volume: 256, Issue:8

    Topics: Anti-Inflammatory Agents; Aorta; Aortic Aneurysm; Aortic Dissection; Biopsy; Brachial Plexus; Brachi

2009
Vesiculo-bullous dermatomyositis: report of three cases.
    Dermatology online journal, 2009, Apr-15, Volume: 15, Issue:4

    Topics: Anti-Inflammatory Agents; Breast Neoplasms; Dermatomyositis; Fatigue; Female; Follow-Up Studies; Hum

2009
Macrophagic myofascitis associated with rheumatoid arthritis.
    Rheumatology international, 2010, Volume: 30, Issue:7

    Topics: Arthritis, Rheumatoid; Biopsy; Fascia; Female; Gait Disorders, Neurologic; Humans; Immunosuppressive

2010
Clinical characteristics and outcomes of juvenile and adult dermatomyositis.
    Journal of Korean medical science, 2009, Volume: 24, Issue:4

    Topics: Adolescent; Adult; Age of Onset; Aged; Anti-Inflammatory Agents; Calcification, Physiologic; Dermato

2009
Systemic sclerosis in aquaporin-4 antibody-positive longitudinally extensive transverse myelitis.
    Journal of the neurological sciences, 2011, Apr-15, Volume: 303, Issue:1-2

    Topics: Anti-Inflammatory Agents; Aquaporin 4; Autoantibodies; Brain; Facial Nerve Diseases; Female; Humans;

2011
Silk road occlusion.
    Lancet (London, England), 2011, Mar-19, Volume: 377, Issue:9770

    Topics: Abdominal Pain; Anorexia; Arterial Occlusive Diseases; Behcet Syndrome; Blood Sedimentation; Brain I

2011
Fulminant myelopathy following neurogenic proximal weakness associated with human T-cell lymphotropic virus type I infection.
    Internal medicine (Tokyo, Japan), 2011, Volume: 50, Issue:8

    Topics: Aged; Glucocorticoids; Humans; Magnetic Resonance Imaging; Male; Muscle Weakness; Muscular Atrophy;

2011
Unusual presentation as an adult onset painful myopathy in a Thai patient with Becker muscular dystrophy.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2011, Volume: 94 Suppl 1

    Topics: Adult; Age of Onset; Asian People; Creatine Kinase; Dystrophin; Electromyography; Genetic Diseases,

2011
Transient delayed facial nerve palsy after inferior alveolar nerve block anesthesia.
    Anesthesia progress, 2012,Spring, Volume: 59, Issue:1

    Topics: Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents; Carticaine; Dental Restoration, Pe

2012
A 90 year old man with difficulty swallowing and proximal muscle weakness.
    BMJ (Clinical research ed.), 2012, Apr-04, Volume: 344

    Topics: Aged, 80 and over; Cholinesterase Inhibitors; Deglutition Disorders; Diagnosis, Differential; Fatal

2012
An acquired source of seizures.
    BMJ (Clinical research ed.), 2012, May-03, Volume: 344

    Topics: Adult; Albendazole; Animals; Anti-Inflammatory Agents; Anticonvulsants; Antiparasitic Agents; Develo

2012
Medium term outcome in Bell's palsy in children.
    Emergency medicine journal : EMJ, 2013, Volume: 30, Issue:6

    Topics: Bell Palsy; Child; Cohort Studies; Emergency Medical Services; Follow-Up Studies; Glucocorticoids; H

2013
Idiopathic cranial polyneuropathy with unilateral IX and X and contralateral XI nerve palsy in a 4-year-old boy.
    Pediatric neurology, 2012, Volume: 47, Issue:3

    Topics: Accessory Nerve Diseases; Anti-Inflammatory Agents; Child, Preschool; Functional Laterality; Glossop

2012
Intensive exercise and a patient in acute phase of polymyositis.
    Journal of back and musculoskeletal rehabilitation, 2012, Volume: 25, Issue:4

    Topics: Acute Disease; Combined Modality Therapy; Electromyography; Exercise Therapy; Female; Humans; Muscle

2012
The effect of early prednisolone treatment on the generalization rate in ocular myasthenia gravis.
    European journal of neurology, 2013, Volume: 20, Issue:4

    Topics: Adult; Age of Onset; Aged; Anti-Inflammatory Agents; Autoantibodies; Blepharoptosis; Cholinesterase

2013
Osteoporosis with underlying connective tissue disease: an unusual case.
    Annals of the New York Academy of Sciences, 2002, Volume: 966

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Accidental Falls; Adult; Anti-Ulcer Agents; Antibodies, Ant

2002
Dissociation between titer of anti-ganglioside antibody and severity of symptoms in a case of Guillain-Barré syndrome with treatment-related fluctuation.
    Journal of the neurological sciences, 2003, Jun-15, Volume: 210, Issue:1-2

    Topics: Adult; Anti-Inflammatory Agents; Antibodies; Cerebrospinal Fluid Proteins; Combined Modality Therapy

2003
[Excessive hyperferritinemia as an indication of a reactive hemophagocytosis syndrome].
    Deutsche medizinische Wochenschrift (1946), 2003, Jun-06, Volume: 128, Issue:23

    Topics: Adolescent; Alanine Transaminase; Anti-Inflammatory Agents; Arthritis; Aspartate Aminotransferases;

2003
Treatment of steroid-unresponsive tumefactive demyelinating disease with plasma exchange.
    Neurology, 2003, Oct-14, Volume: 61, Issue:7

    Topics: Adult; Combined Modality Therapy; Demyelinating Diseases; Disease Progression; Female; Gadolinium; H

2003
Multifocal acquired demyelinating sensory and motor neuropathy: report of a case and review of the literature.
    Acta neurologica Taiwanica, 2004, Volume: 13, Issue:1

    Topics: Adult; Anti-Inflammatory Agents; Demyelinating Diseases; Diagnosis, Differential; Electric Stimulati

2004
A limited form of Churg-Strauss syndrome presenting without asthma and eosinophilia.
    The Medical journal of Australia, 2004, Nov-01, Volume: 181, Issue:9

    Topics: Adult; Amputation, Surgical; Anti-Inflammatory Agents; Antibodies, Antineutrophil Cytoplasmic; Asthm

2004
Multicentric reticulohistiocytosis with prominent cutaneous lesions and proximal muscle weakness masquerading as dermatomyositis.
    The Journal of rheumatology, 2005, Volume: 32, Issue:1

    Topics: Dermatomyositis; Diagnosis, Differential; Drug Therapy, Combination; Female; Histiocytosis; Humans;

2005
Subacute inflammatory demyelinating polyneuropathy in children.
    Neurology, 2005, May-24, Volume: 64, Issue:10

    Topics: Adolescent; Age Factors; Anti-Inflammatory Agents; Child; Child, Preschool; Chronic Disease; Disease

2005
Longstanding right-hand weakness in a patient with myasthenia gravis.
    Muscle & nerve, 2006, Volume: 34, Issue:5

    Topics: Adult; Anti-Inflammatory Agents; Autoantibodies; Chronic Disease; Disease Progression; Electric Stim

2006
Weekly oral prednisolone improves survival and strength in male mdx mice.
    Muscle & nerve, 2007, Volume: 35, Issue:1

    Topics: Administration, Oral; Age Factors; Animals; Anti-Inflammatory Agents; Body Weight; Disease Models, A

2007
Progressive myopathy with up-regulation of MHC-I associated with statin therapy.
    Neuromuscular disorders : NMD, 2007, Volume: 17, Issue:2

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents; Atorvastatin; Creatine Kinase; Female; Folic Acid

2007
Vocal cord paralysis in myasthenia gravis with anti-MuSK antibodies.
    Neurology, 2007, Feb-20, Volume: 68, Issue:8

    Topics: Autoantibodies; Biomarkers; Bulbar Palsy, Progressive; Deglutition Disorders; Facial Muscles; Humans

2007
Sarcoid myositis with muscle weakness as a presenting symptom.
    Modern rheumatology, 2007, Volume: 17, Issue:3

    Topics: Anti-Inflammatory Agents; Female; Humans; Middle Aged; Muscle Weakness; Polymyositis; Prednisolone;

2007
Devic's neuromyelitis optica in an infant case.
    Journal of child neurology, 2007, Volume: 22, Issue:9

    Topics: Atrophy; Demyelinating Autoimmune Diseases, CNS; Humans; Immunosuppressive Agents; Infant; Male; Mus

2007
Dropped-head syndrome due to steroid responsive focal myositis: a case report and review of the literature.
    Journal of the neurological sciences, 2008, Apr-15, Volume: 267, Issue:1-2

    Topics: Adrenal Cortex Hormones; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Azathioprine; Biopsy; Di

2008
Localized muscle wasting as an initial symptom of skeletal muscle lymphoma.
    Journal of the neurological sciences, 1998, Jan-21, Volume: 154, Issue:1

    Topics: Adult; Anti-Inflammatory Agents; Antineoplastic Agents, Hormonal; Diagnosis, Differential; Humans; I

1998
Calcitriol-mediated hypercalcaemia and increased interleukins in a patient with sarcoid myopathy.
    Clinical rheumatology, 1999, Volume: 18, Issue:6

    Topics: Antirheumatic Agents; Calcitonin; Calcitriol; Chloroquine; Clodronic Acid; Female; Humans; Hypercalc

1999
Prednisolone-induced muscle dysfunction is caused more by atrophy than by altered acetylcholine receptor expression.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Electric Stimulation; Glucocorticoids; Hindlimb; Male; Mu

2000
Motor dominant neuropathy in Sjögren's syndrome: report of two cases.
    Internal medicine (Tokyo, Japan), 2002, Volume: 41, Issue:2

    Topics: Aged; Autoimmune Diseases; Biopsy; Diagnosis, Differential; Female; Guillain-Barre Syndrome; Humans;

2002
Polyarteritis nodosa presenting as polymyositis.
    Seminars in arthritis and rheumatism, 2002, Volume: 31, Issue:6

    Topics: Adult; Antirheumatic Agents; Creatine Kinase; Diagnosis, Differential; Drug Therapy, Combination; Hu

2002