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prednisolone and Mucopolysaccharidosis III

prednisolone has been researched along with Mucopolysaccharidosis III in 2 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Mucopolysaccharidosis III: Mucopolysaccharidosis characterized by heparitin sulfate in the urine, progressive mental retardation, mild dwarfism, and other skeletal disorders. There are four clinically indistinguishable but biochemically distinct forms, each due to a deficiency of a different enzyme.

Research Excerpts

ExcerptRelevanceReference
"Mucopolysaccharidosis IIIB is a paediatric lysosomal storage disease caused by deficiency of the enzyme α-N-acetylglucosaminidase (NAGLU), involved in the degradation of the glycosaminoglycan heparan sulphate."1.48Macrophage enzyme and reduced inflammation drive brain correction of mucopolysaccharidosis IIIB by stem cell gene therapy. ( Bigger, BW; D'Souza, Z; Dickson, PI; Ellison, SM; Fil, D; Gleitz, HFE; Holley, RJ; Kan, SH; Langford-Smith, AWW; Liao, A; McDermott, J; O'Leary, C; Parker, H; Rowlston, S; Senthivel, N; Wilkinson, FL, 2018)
"The mechanism of neuropathology in MPS IIIB is unclear."1.35Innate and adaptive immune activation in the brain of MPS IIIB mouse model. ( Auer, H; Best, V; Charrier, A; DiRosario, J; Divers, E; Etter, J; Fu, H; Jukkola, P; McCarty, DM; Newsom, DL; Wang, C, 2009)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Holley, RJ1
Ellison, SM1
Fil, D1
O'Leary, C1
McDermott, J1
Senthivel, N1
Langford-Smith, AWW1
Wilkinson, FL1
D'Souza, Z1
Parker, H1
Liao, A1
Rowlston, S1
Gleitz, HFE1
Kan, SH1
Dickson, PI1
Bigger, BW1
DiRosario, J1
Divers, E1
Wang, C1
Etter, J1
Charrier, A1
Jukkola, P1
Auer, H1
Best, V1
Newsom, DL1
McCarty, DM1
Fu, H1

Other Studies

2 other studies available for prednisolone and Mucopolysaccharidosis III

ArticleYear
Macrophage enzyme and reduced inflammation drive brain correction of mucopolysaccharidosis IIIB by stem cell gene therapy.
    Brain : a journal of neurology, 2018, 01-01, Volume: 141, Issue:1

    Topics: Animals; Brain; Cytokines; Disease Models, Animal; Encephalitis; Female; Genetic Therapy; Gliosis; G

2018
Innate and adaptive immune activation in the brain of MPS IIIB mouse model.
    Journal of neuroscience research, 2009, Volume: 87, Issue:4

    Topics: Animals; Astrocytes; Autoantibodies; Brain; Demyelinating Diseases; Disease Models, Animal; Disease

2009