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prednisolone and Meningitis, Tuberculous

prednisolone has been researched along with Meningitis, Tuberculous in 48 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Research Excerpts

ExcerptRelevanceReference
"Levofloxacin was discontinued more frequently than rifampicin due to SAEs (16 versus 4, P = 0."2.79Safety and efficacy of levofloxacin versus rifampicin in tuberculous meningitis: an open-label randomized controlled trial. ( Bhoi, SK; Kalita, J; Misra, UK; Prasad, S, 2014)
"Tuberculous meningitis is a serious form of tuberculosis (TB) that affects the meninges that cover a person's brain and spinal cord."2.53Corticosteroids for managing tuberculous meningitis. ( Prasad, K; Ryan, H; Singh, MB, 2016)
"However, Listeria meningitis (LM) may cause lymphocytic dominant pleocytosis in 30% of the patients, particularly in elderly ones."2.41[Neuro-infections to be borne in mind]. ( Kamei, S; Mizutani, T, 2001)
"There has been reports on pediatric TB meningitis manifesting with fever and seizures, altered sensorium or focal deficits."1.56Tuberculous meningitis manifesting with neuroregression in a eleven month child. ( Kasinathan, A; Palanisamy, S; Serane, VK, 2020)
"Diagnosis of tumefactive demyelination was made on the basis of typical MRI findings."1.35Tumefactive demyelination. ( Deore, RA; Nadkar, MY; Singh, R, 2008)
"Patients with non-communicating hydrocephalus received ventriculo-peritoneal shunts shortly after admission while communicating hydrocephalus was treated with oral acetazolamide (100 mg/kg/day) and furosemide (1 mg/kg/day) in 3-4 divided doses."1.31Long-term follow up of childhood tuberculous meningitis. ( Burger, M; Donald, P; Fertig, G; Schoeman, J; Springer, P; van Rensburg, AJ; van Zyl, F; Wait, J, 2002)
"When prednisolone was again tapered down, increased nuchal rigidity, abducent nerve palsy and papilloedema appeared again with a marked increase in the number of CSF cells of 1309/mm3 on the 91th day."1.31[Repeated deterioration of tuberculous meningitis due to a reduction in the corticosteroid dosage during chemotherapy]. ( Itoh, H; Miyoshi, Y; Murai, H; Noda, S, 2000)
"Two patients with tuberculous meningitis are described, who developed intracranial tuberculoma while receiving antituberculous therapy."1.28Paradoxical response to chemotherapy for intracranial tuberculoma: two case reports from Saudi Arabia. ( AbdulJabbar, M, 1991)
"A patient with tuberculous meningitis is described, who developed brainstem tuberculoma after 7 months of adequate drug therapy and while improving satisfactorily."1.27Appearance of tuberculoma during the course of TB meningitis. ( Borah, NC; Goulatia, RK; Maheshwari, MC; Mishra, NK, 1984)

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-199014 (29.17)18.7374
1990's8 (16.67)18.2507
2000's13 (27.08)29.6817
2010's11 (22.92)24.3611
2020's2 (4.17)2.80

Authors

AuthorsStudies
Pandey, PC1
Kalita, J2
Sardhara, J1
Jain, N1
Prasad, P1
Kasinathan, A1
Serane, VK1
Palanisamy, S1
Machida, A1
Ishihara, T1
Amano, E1
Otsu, S1
Shah, I2
Meshram, L1
Misra, UK1
Prasad, S1
Bhoi, SK1
Molton, JS1
Huggan, PJ1
Archuleta, S1
Alsleben, N1
Garcia-Prats, AJ1
Hesseling, AC1
Willemse, M1
Donald, PR1
Schaaf, HS1
Prasad, K4
Singh, MB2
Ryan, H1
Nadkar, MY1
Deore, RA1
Singh, R1
Basu, S1
Kumar, A1
Das, BK1
Ueda, A1
Ueda, M1
Mihara, T1
Ito, S1
Asakura, K1
Mutoh, T1
Sugita, T1
Katoh, H1
Hayashi, D1
Ohnaka, Y1
Nakajima, M1
Kawamura, M1
Petramfar, P1
Yousefian, M1
Ashraf, MH1
Davarpanah, MA1
Rahmati, H1
Morioka, H1
Matsumoto, S1
Kojima, E1
Takada, K1
Iwata, S1
Okachi, S1
Schoeman, J1
Wait, J1
Burger, M1
van Zyl, F1
Fertig, G1
van Rensburg, AJ1
Springer, P1
Donald, P1
Kamei, S1
Mizutani, T1
SANTOPADRE, I1
MISRA, SS1
KHANNA, BK2
TANDON, RN1
WAHREN, W1
SPIESS, H1
GRAZIA, G1
VECSEY, A1
Shaharao, VB1
Pawar, M1
Agarwal, R1
Bavdekar, SB1
Lolekha, R1
Chokephaibulkit, K1
Vanprapar, N1
Phongsamart, W1
Chearskul, S1
Takahashi, S1
Takahashi, T1
Kuragano, T1
Nagura, Y1
Fujita, T1
Nakayama, T1
Matsumoto, K1
Iliopoulos, A1
Kedikoglou, S1
Laxanis, S1
Kourouklis, S1
Katsaros, E1
Volmink, J2
Menon, GR2
Borah, NC1
Maheshwari, MC1
Mishra, NK1
Goulatia, RK1
van Woensel, JB1
Hoogeveen, CG1
Begeer, JH1
Visser, G1
Kimpen, JL1
Mukendi Kavulu, R1
Tshilolo Mwepu, L1
Chotmongkol, V2
Jitpimolmard, S1
Thavornpitak, Y1
Chang, AB1
Grimwood, K1
Harvey, AS1
Rosenfeld, JV1
Olinsky, A1
Tsushima, K1
Kubo, K1
Miyoshi, Y1
Noda, S1
Murai, H1
Itoh, H1
Takahara, M1
Millar, JW1
Horne, NW1
Rose, FC1
AbdulJabbar, M1
Gourie-Devi, M1
Satishchandra, P1
Stange, G1
Tauchnitz, C1
Storch, W1
Ellorhaoui, M1
Abello, VB1
Riley, HD1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Double Blind Placebo Controlled Trial of Adjunctive Dexamethasone for the Treatment of HIV-infected Adults With Tuberculous Meningitis[NCT03092817]Phase 3520 participants (Actual)Interventional2017-05-25Active, not recruiting
A Randomized Double Blind Placebo Controlled Non-inferiority Trial of Adjunctive Dexamethasone for the Treatment of HIV-uninfected Adults With Tuberculous Meningitis Stratified by Leukotriene A4 Hydrolase Genotype[NCT03100786]Phase 3640 participants (Anticipated)Interventional2018-02-08Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for prednisolone and Meningitis, Tuberculous

ArticleYear
Corticosteroids for managing tuberculous meningitis.
    The Cochrane database of systematic reviews, 2016, Apr-28, Volume: 4

    Topics: Adult; Antitubercular Agents; Chemotherapy, Adjuvant; Child; Dexamethasone; Glucocorticoids; Humans;

2016
Corticosteroids for managing tuberculous meningitis.
    The Cochrane database of systematic reviews, 2016, Apr-28, Volume: 4

    Topics: Adult; Antitubercular Agents; Chemotherapy, Adjuvant; Child; Dexamethasone; Glucocorticoids; Humans;

2016
Corticosteroids for managing tuberculous meningitis.
    The Cochrane database of systematic reviews, 2016, Apr-28, Volume: 4

    Topics: Adult; Antitubercular Agents; Chemotherapy, Adjuvant; Child; Dexamethasone; Glucocorticoids; Humans;

2016
Corticosteroids for managing tuberculous meningitis.
    The Cochrane database of systematic reviews, 2016, Apr-28, Volume: 4

    Topics: Adult; Antitubercular Agents; Chemotherapy, Adjuvant; Child; Dexamethasone; Glucocorticoids; Humans;

2016
[Hypertrophic pachymeningitis: three adult cases and a review of the literature].
    Rinsho shinkeigaku = Clinical neurology, 2011, Volume: 51, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Blood Sedimentation; C-Reactive Protein; Cra

2011
[Neuro-infections to be borne in mind].
    Rinsho shinkeigaku = Clinical neurology, 2001, Volume: 41, Issue:12

    Topics: Adult; Aged; Antitubercular Agents; Encephalitis, Herpes Simplex; Endocarditis, Bacterial; Fatal Out

2001
WITHDRAWN: Steroids for treating tuberculous meningitis.
    The Cochrane database of systematic reviews, 2007, Jul-18, Issue:1

    Topics: Adult; Antitubercular Agents; Chemotherapy, Adjuvant; Child; Dexamethasone; Drug Therapy, Combinatio

2007
Corticosteroids for managing tuberculous meningitis.
    The Cochrane database of systematic reviews, 2008, Jan-23, Issue:1

    Topics: Adult; Antitubercular Agents; Chemotherapy, Adjuvant; Child; Dexamethasone; Glucocorticoids; Humans;

2008
Corticosteroids for managing tuberculous meningitis.
    The Cochrane database of systematic reviews, 2008, Jan-23, Issue:1

    Topics: Adult; Antitubercular Agents; Chemotherapy, Adjuvant; Child; Dexamethasone; Glucocorticoids; Humans;

2008
Corticosteroids for managing tuberculous meningitis.
    The Cochrane database of systematic reviews, 2008, Jan-23, Issue:1

    Topics: Adult; Antitubercular Agents; Chemotherapy, Adjuvant; Child; Dexamethasone; Glucocorticoids; Humans;

2008
Corticosteroids for managing tuberculous meningitis.
    The Cochrane database of systematic reviews, 2008, Jan-23, Issue:1

    Topics: Adult; Antitubercular Agents; Chemotherapy, Adjuvant; Child; Dexamethasone; Glucocorticoids; Humans;

2008
Steroids for treating tuberculous meningitis.
    The Cochrane database of systematic reviews, 2000, Issue:3

    Topics: Adult; Antitubercular Agents; Chemotherapy, Adjuvant; Child; Dexamethasone; Drug Therapy, Combinatio

2000

Trials

5 trials available for prednisolone and Meningitis, Tuberculous

ArticleYear
High dose versus low dose steroids in children with tuberculous meningitis.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2014, Volume: 21, Issue:5

    Topics: Adolescent; Anti-Inflammatory Agents; Child; Child, Preschool; Dose-Response Relationship, Drug; Dru

2014
Safety and efficacy of levofloxacin versus rifampicin in tuberculous meningitis: an open-label randomized controlled trial.
    The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:8

    Topics: Adolescent; Adult; Aged; Antitubercular Agents; Aspirin; Drug Therapy, Combination; Ethambutol; Fema

2014
Corticosteroid in tuberculous meningitis.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 1996, Volume: 79, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Antitubercular Agents; Cerebro

1996
Treatment of tuberculous meningitis with 6-month course of chemotherapy.
    The Southeast Asian journal of tropical medicine and public health, 1991, Volume: 22, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Antitubercular Agents; Drug Therapy, Combination; Follow-Up

1991
Hyaluronidase as an adjuvant in the management of tuberculous spinal arachnoiditis.
    Journal of the neurological sciences, 1991, Volume: 102, Issue:1

    Topics: Adolescent; Adult; Aged; Antitubercular Agents; Arachnoiditis; Child; Drug Evaluation; Extracellular

1991

Other Studies

37 other studies available for prednisolone and Meningitis, Tuberculous

ArticleYear
Racemose neurocysticercosis simulating tuberculous meningitis.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2022, Volume: 41, Issue:11

    Topics: Adult; Dexamethasone; Humans; Hydrocephalus; Leukocytosis; Male; Neurocysticercosis; Prednisolone; T

2022
Tuberculous meningitis manifesting with neuroregression in a eleven month child.
    The Indian journal of tuberculosis, 2020, Volume: 67, Issue:1

    Topics: Acetazolamide; Antitubercular Agents; Carbonic Anhydrase Inhibitors; Cerebrospinal Fluid; Early Medi

2020
Late-onset paradoxical reactions 10 years after treatment for tuberculous meningitis in an HIV-negative patient: a case report.
    BMC infectious diseases, 2018, 07-06, Volume: 18, Issue:1

    Topics: Administration, Oral; Adrenal Cortex Hormones; Adult; Antitubercular Agents; Brain; Female; Headache

2018
Infliximab therapy in two cases of severe neurotuberculosis paradoxical reaction.
    The Medical journal of Australia, 2015, Feb-16, Volume: 202, Issue:3

    Topics: Adult; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antitubercular Agents; Dexamethasone; Etham

2015
Successful Treatment of a Child With Extensively Drug-Resistant Tuberculous Meningitis.
    Journal of the Pediatric Infectious Diseases Society, 2015, Volume: 4, Issue:3

    Topics: Anti-Inflammatory Agents; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Child, Pres

2015
Tumefactive demyelination.
    The Journal of the Association of Physicians of India, 2008, Volume: 56

    Topics: Adult; Brain; Demyelinating Diseases; Diagnosis, Differential; Female; Glucocorticoids; Humans; Inje

2008
Steroid therapy in children with tuberculous meningitis.
    Scandinavian journal of infectious diseases, 2009, Volume: 41, Issue:6-7

    Topics: Anti-Inflammatory Agents; Antitubercular Agents; Child, Preschool; Female; Humans; Infant; Male; Pre

2009
Perinatal tuberculosis: two unusual cases.
    Annals of tropical paediatrics, 2011, Volume: 31, Issue:1

    Topics: Anti-HIV Agents; Anti-Inflammatory Agents; Antimalarials; Drug Therapy, Combination; Endometritis; F

2011
[Tuberculous cranial pachymeningitis presenting with long-standing diffuse brain dysfunction].
    Rinsho shinkeigaku = Clinical neurology, 2011, Volume: 51, Issue:4

    Topics: Antitubercular Agents; Attention Deficit Disorder with Hyperactivity; Cerebrospinal Fluid; Chronic D

2011
Meningoencephalitis with Aspergillus and mycobacterium tuberculosis in a renal transplant recipient.
    Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation, 2011, Volume: 9, Issue:1

    Topics: Adult; Anti-Bacterial Agents; Antifungal Agents; Antitubercular Agents; Aspergillus; Bacteriological

2011
Paradoxical infarct in tuberculous meningitis: a case report.
    Internal medicine (Tokyo, Japan), 2012, Volume: 51, Issue:8

    Topics: Aged; Antitubercular Agents; Cerebral Infarction; Female; Humans; Prednisolone; Tuberculosis, Mening

2012
Long-term follow up of childhood tuberculous meningitis.
    Developmental medicine and child neurology, 2002, Volume: 44, Issue:8

    Topics: Acetazolamide; Anti-Inflammatory Agents; Antitubercular Agents; Brain; Child; Cognition Disorders; D

2002
[Therapeutic use by intraspinal route in the course of tuberculous meningitis of a new preparation of hydrosoluble prednisolone].
    Minerva medica, 1958, Feb-21, Volume: 49, Issue:15

    Topics: Humans; Prednisolone; Tuberculosis; Tuberculosis, Meningeal

1958
Corticosteroids in tuberculous meningitis.
    Journal of the Indian Medical Association, 1961, Feb-01, Volume: 36

    Topics: Adrenal Cortex Hormones; Cardiovascular Agents; Cortisone; Glucocorticoids; Humans; Prednisolone; Tu

1961
Pulmonary tuberculosis following corticosteroid therapy for tuberculous meningitis. (A report of 2 cases).
    Journal of the Indian Medical Association, 1959, Nov-01, Volume: 33

    Topics: Adrenal Cortex Hormones; Humans; Prednisolone; Tuberculosis; Tuberculosis, Meningeal; Tuberculosis,

1959
[ON THE CORTISONE TREATMENT OF VARIOUS INFECTIOUS DISEASES OF THE NERVOUS SYSTEM].
    Deutsche Zeitschrift fur Nervenheilkunde, 1963, Jul-10, Volume: 185

    Topics: Cortisone; Encephalitis; Encephalitis, Arbovirus; Herpes Zoster; Humans; Meningitis; Myelitis; Predn

1963
[THE ACTION OF CORTICOIDS IN TUBERCULOSIS].
    Revista chilena de pediatria, 1963, Volume: 34

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Carbon Isotopes; Cortisone; Guinea Pigs; Isoni

1963
[INDICATIONS AND UTILITY OF INTRATHECAL AND INTRAVENTRICULAR TREATMENT IN THE THERAPY OF TUBERCULAR MENINGITIS].
    La Clinica pediatrica, 1963, Volume: 45

    Topics: Child; Chlorpromazine; Humans; Injections; Injections, Spinal; Isoniazid; Prednisolone; Pyrazinamide

1963
[OUR RESULTS IN THE HORMONAL TREATMENT OF TUBERCULOUS PATIENTS WITH A REFERENCE TO ACUTE INFLAMMATORY FORMS].
    Tuberkulozis es tudobetegsegek, 1964, Volume: 17

    Topics: Adrenocorticotropic Hormone; Antitubercular Agents; Drug Therapy; Empyema; Empyema, Tuberculous; Hum

1964
Intra-medullary tuberculoma occurring during treatment of tuberculous meningitis.
    Indian journal of pediatrics, 2004, Volume: 71, Issue:1

    Topics: Antitubercular Agents; Child; Dexamethasone; Drug Therapy, Combination; Female; Follow-Up Studies; H

2004
Breakthrough neurological manifestation during appropriate antituberculous therapy of miliary tuberculosis.
    The Southeast Asian journal of tropical medicine and public health, 2003, Volume: 34, Issue:3

    Topics: Antitubercular Agents; Arachnoiditis; Drug Hypersensitivity; Drug Therapy, Combination; Female; Gluc

2003
[A case of chronic renal failure complicated with tuberculous meningitis successfully diagnosed by nested polymerase chain reaction (PCR)].
    Nihon Jinzo Gakkai shi, 2005, Volume: 47, Issue:2

    Topics: Adult; DNA, Bacterial; Female; Glomerulonephritis; Humans; Immunocompromised Host; Kidney Failure, C

2005
A case of tuberculous meningoencephalitis in a patient with Behçet's disease.
    Clinical rheumatology, 2006, Volume: 25, Issue:1

    Topics: Adult; Antitubercular Agents; Behcet Syndrome; Colchicine; Cyclosporine; DNA, Bacterial; Drug Therap

2006
Paradoxical expansion of intracranial tuberculomas during chemotherapy.
    Lancet (London, England), 1984, Sep-29, Volume: 2, Issue:8405

    Topics: Adolescent; Child; Child, Preschool; Female; Humans; Infant; Male; Prednisolone; Tuberculoma; Tuberc

1984
Appearance of tuberculoma during the course of TB meningitis.
    Journal of neurology, 1984, Volume: 231, Issue:5

    Topics: Adolescent; Brain Stem; Female; Humans; Isoniazid; Prednisolone; Pyrazinamide; Rifampin; Tomography,

1984
Intracranial tuberculosis in The Netherlands: four paediatric cases.
    European journal of pediatrics, 1995, Volume: 154, Issue:7

    Topics: Antitubercular Agents; Brain; Child; Child, Preschool; Contact Tracing; Drug Therapy, Combination; F

1995
[Tuberculosis of the central nervous system: value of early polychemotherapy. Apropos of 2 cases].
    Pediatrie, 1993, Volume: 48, Issue:6

    Topics: Child; Drug Therapy, Combination; Ethambutol; Female; Humans; Isoniazid; Male; Prednisolone; Rifampi

1993
Central nervous system tuberculosis after resolution of miliary tuberculosis.
    The Pediatric infectious disease journal, 1998, Volume: 17, Issue:6

    Topics: Antitubercular Agents; Central Nervous System Infections; Dexamethasone; Drug Therapy, Combination;

1998
[Tuberculous meningitis developed during treatment for systemic lupus erythematosus (SLE)].
    Kekkaku : [Tuberculosis], 1999, Volume: 74, Issue:1

    Topics: Adenosine Deaminase; Anti-Inflammatory Agents; Female; Humans; Immunosorbent Techniques; Lupus Eryth

1999
[Repeated deterioration of tuberculous meningitis due to a reduction in the corticosteroid dosage during chemotherapy].
    Rinsho shinkeigaku = Clinical neurology, 2000, Volume: 40, Issue:10

    Topics: Adolescent; Antitubercular Agents; Disease Progression; Drug Therapy, Combination; Humans; Male; Pre

2000
[A case of miliary tuberculosis complicated with SIADH, brain tuberculoma, and tuberculous meningitis].
    Kekkaku : [Tuberculosis], 2002, Volume: 77, Issue:2

    Topics: Antitubercular Agents; Brain Diseases; Drug Therapy, Combination; Humans; Inappropriate ADH Syndrome

2002
Tuberculosis in immunosuppressed patients.
    Lancet (London, England), 1979, Jun-02, Volume: 1, Issue:8127

    Topics: Adult; Aged; Azathioprine; Chlorambucil; Drug Therapy, Combination; Female; Humans; Immunosuppressio

1979
Relapsing meningoencephalitis ? cerebral sarcoidosis.
    Proceedings of the Royal Society of Medicine, 1975, Volume: 68, Issue:9

    Topics: Adrenocorticotropic Hormone; Adult; Aminosalicylic Acids; Brain Diseases; Dexamethasone; Diagnosis,

1975
Paradoxical response to chemotherapy for intracranial tuberculoma: two case reports from Saudi Arabia.
    The Journal of tropical medicine and hygiene, 1991, Volume: 94, Issue:6

    Topics: Adult; Antitubercular Agents; Brain; Female; Humans; Magnetic Resonance Imaging; Male; Prednisolone;

1991
[Therapy of tuberculous meningitis].
    Archiv fur klinische und experimentelle Ohren- Nasen- und Kehlkopfheilkunde, 1972, Volume: 202, Issue:2

    Topics: Adult; Antitubercular Agents; Deafness; Female; Hearing Disorders; Humans; Male; Prednisolone; Strep

1972
[Chronic tuberculous meningitis in a case of known Mycobacterium kansasii infection].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1974, Jun-15, Volume: 29, Issue:12

    Topics: Adult; Burns; Cell Count; Cerebrospinal Fluid; Cerebrospinal Fluid Proteins; Drug Therapy, Combinati

1974
The use of adrenal corticosteroids in the management of meningitis.
    The Journal of the Oklahoma State Medical Association, 1972, Volume: 65, Issue:7

    Topics: Anti-Bacterial Agents; Female; Humans; Hydrocephalus; Infant; Meningitis; Meningitis, Haemophilus; P

1972