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prednisolone and Malaria

prednisolone has been researched along with Malaria in 15 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.

Research Excerpts

ExcerptRelevanceReference
"We conducted a double-blind, randomized, parallel group study to examine and compare the antipruritic effects of promethazine, niacin, prednisolone and their combination on pruritus induced by chloroquine, in 28 historical itching patients with parasitologically proven malaria fever."9.08Chloroquine-induced pruritus in malaria fever: contribution of malaria parasitaemia and the effects of prednisolone, niacin, and their combination, compared with antihistamine. ( Adebayo, RA; Ajayi, AA; Onayemi, O; Sofowora, GG; Udoh, SJ, 1997)
"A 59-year-old man took mefloquine (antimalarial drug), total dose of 1,000 mg, to prevent malaria before and during traveling to South Africa."7.73[Case of drug-induced pneumonia possibly due to mefloquine (antimalarial drug)]. ( Goto, S; Inoue, T; Maeda, Y; Maniwa, K; Minakuchi, M; Noma, S; Sakuramoto, M; Taguchi, Y; Takeda, T; Tanaka, E; Terada, K, 2005)
"Radioisotope red-cell survival studies were carried out in 20 patients with falciparum malaria following quinine therapy."7.66The effect of prednisolone on red cell survival in patients with falciparum malaria. ( Charoenlarp, P; Chat-panyaporn, P; Vanijanonta, S, 1979)
" Treatment with antimalarials and folic acid is usually followed by a rapid remission, but response is slow in about 25% of patients and haemolysis continues uncontrolled in about 5%."7.65Severe haemolytic anaemia in pregnancy in Nigerians treated with prednisolone. ( Allan, NC; Fleming, AF, 1969)
"The malaria was resistant to chloroquine at the RI level, the first such case reported from BMH Dharan."5.27Chloroquine resistant malignant subtertian malaria unmasked by systematic steroid therapy. ( Henderson, A; Livesey, JR, 1983)
"We conducted a double-blind, randomized, parallel group study to examine and compare the antipruritic effects of promethazine, niacin, prednisolone and their combination on pruritus induced by chloroquine, in 28 historical itching patients with parasitologically proven malaria fever."5.08Chloroquine-induced pruritus in malaria fever: contribution of malaria parasitaemia and the effects of prednisolone, niacin, and their combination, compared with antihistamine. ( Adebayo, RA; Ajayi, AA; Onayemi, O; Sofowora, GG; Udoh, SJ, 1997)
"A 59-year-old man took mefloquine (antimalarial drug), total dose of 1,000 mg, to prevent malaria before and during traveling to South Africa."3.73[Case of drug-induced pneumonia possibly due to mefloquine (antimalarial drug)]. ( Goto, S; Inoue, T; Maeda, Y; Maniwa, K; Minakuchi, M; Noma, S; Sakuramoto, M; Taguchi, Y; Takeda, T; Tanaka, E; Terada, K, 2005)
"Radioisotope red-cell survival studies were carried out in 20 patients with falciparum malaria following quinine therapy."3.66The effect of prednisolone on red cell survival in patients with falciparum malaria. ( Charoenlarp, P; Chat-panyaporn, P; Vanijanonta, S, 1979)
"Remission followed prednisolone therapy in 9 out of 21 Nigerian children with the nephrotic syndrome who had highly selective proteinuria (CG/CA less than 15%)."3.65Differential protein clearances and response to treatment in Nigerian nephrotic children. ( Adeniyi, A; Hendrickse, RG; Soothill, JF, 1976)
" Treatment with antimalarials and folic acid is usually followed by a rapid remission, but response is slow in about 25% of patients and haemolysis continues uncontrolled in about 5%."3.65Severe haemolytic anaemia in pregnancy in Nigerians treated with prednisolone. ( Allan, NC; Fleming, AF, 1969)
"The malaria was resistant to chloroquine at the RI level, the first such case reported from BMH Dharan."1.27Chloroquine resistant malignant subtertian malaria unmasked by systematic steroid therapy. ( Henderson, A; Livesey, JR, 1983)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199011 (73.33)18.7374
1990's1 (6.67)18.2507
2000's2 (13.33)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sharma, V1
Samant, R1
Hegde, A1
Bhaja, K1
MERCADO, TI1
VON BRAND, T1
Inoue, T1
Tanaka, E1
Sakuramoto, M1
Minakuchi, M1
Maeda, Y1
Maniwa, K1
Terada, K1
Goto, S1
Takeda, T1
Noma, S1
Taguchi, Y1
Livesey, JR1
Henderson, A1
Adebayo, RA1
Sofowora, GG1
Onayemi, O1
Udoh, SJ1
Ajayi, AA1
Thong, BY1
Leong, KP1
Chng, HH1
Charoenlarp, P1
Vanijanonta, S1
Chat-panyaporn, P1
Adeniyi, A3
Hendrickse, RG4
Soothill, JF1
Zafar, MH1
Noor, NA1
Gupta, MM1
Dang, HS1
Edington, GM1
Glasgow, EF1
White, RH1
Houba, V2
Fleming, AF1
Allan, NC1
Smitskamp, H1
Wolthuis, FH1

Trials

2 trials available for prednisolone and Malaria

ArticleYear
Chloroquine-induced pruritus in malaria fever: contribution of malaria parasitaemia and the effects of prednisolone, niacin, and their combination, compared with antihistamine.
    British journal of clinical pharmacology, 1997, Volume: 44, Issue:2

    Topics: Adult; Animals; Antimalarials; Area Under Curve; Chloroquine; Double-Blind Method; Drug Therapy, Com

1997
Selectivity of proteinuria and response to prednisolone or immunosuppressive drugs in children with malarial nephrosis.
    Lancet (London, England), 1970, Mar-28, Volume: 1, Issue:7648

    Topics: Albuminuria; Azathioprine; Biopsy; Child; Complement System Proteins; Cyclophosphamide; Female; Fluo

1970

Other Studies

13 other studies available for prednisolone and Malaria

ArticleYear
Autoimmune hemolysis in malaria: a report of three cases.
    The Journal of the Association of Physicians of India, 2012, Volume: 60

    Topics: Adolescent; Anemia, Hemolytic, Autoimmune; Antimalarials; Blood Transfusion; Child; Erythrocyte Coun

2012
The influence of some steroids on glycogenesis in the liver of rats infected with Plasmodium berghei.
    American journal of hygiene, 1957, Volume: 66, Issue:1

    Topics: Animals; Cortisone; Glycogen; Glycogenolysis; Liver; Malaria; Plasmodium berghei; Prednisolone; Pred

1957
[Case of drug-induced pneumonia possibly due to mefloquine (antimalarial drug)].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2005, Volume: 43, Issue:2

    Topics: Acute Disease; Antimalarials; Humans; Malaria; Male; Mefloquine; Methylprednisolone; Middle Aged; Pn

2005
Chloroquine resistant malignant subtertian malaria unmasked by systematic steroid therapy.
    Journal of the Royal Army Medical Corps, 1983, Volume: 129, Issue:3

    Topics: Adult; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Male; Plasmodium falciparum; Predni

1983
Hypersensitivity syndrome associated with dapsone/pyrimethamine (Maloprim) antimalaria chemoprophylaxis.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2002, Volume: 88, Issue:5

    Topics: Adult; Antimalarials; Dapsone; Drug Combinations; Drug Hypersensitivity; Glucocorticoids; Humans; Ma

2002
The effect of prednisolone on red cell survival in patients with falciparum malaria.
    The Southeast Asian journal of tropical medicine and public health, 1979, Volume: 10, Issue:1

    Topics: Adolescent; Adult; Drug Therapy, Combination; Erythrocyte Aging; Female; Hematocrit; Humans; Malaria

1979
Differential protein clearances and response to treatment in Nigerian nephrotic children.
    Archives of disease in childhood, 1976, Volume: 51, Issue:9

    Topics: Age Factors; Albuminuria; Biopsy; Child; Child, Preschool; Cyclophosphamide; Diet; Female; Follow-Up

1976
The quartan malarial nephrotic syndrome.
    Advances in nephrology from the Necker Hospital, 1976, Volume: 6

    Topics: Azathioprine; Capillaries; Child; Child, Preschool; Fluorescent Antibody Technique; Humans; Infant;

1976
Black water fever in Multan.
    JPMA. The Journal of the Pakistan Medical Association, 1988, Volume: 38, Issue:7

    Topics: Adolescent; Animals; Blackwater Fever; Chloroquine; Humans; Malaria; Male; Pakistan; Plasmodium falc

1988
Acute cerebellar ataxia in adults (report of two cases).
    Journal of postgraduate medicine, 1986, Volume: 32, Issue:2

    Topics: Acute Disease; Adult; Age Factors; Cerebellar Ataxia; Chloroquine; Humans; Malaria; Male; Prednisolo

1986
Quartan malarial nephrotic syndrome. Collaborative clinicopathological study in Nigerian children.
    Lancet (London, England), 1972, May-27, Volume: 1, Issue:7761

    Topics: Antimalarials; Azathioprine; Basement Membrane; Biopsy; Capillaries; Child; Child, Preschool; Cyclop

1972
Severe haemolytic anaemia in pregnancy in Nigerians treated with prednisolone.
    British medical journal, 1969, Nov-22, Volume: 4, Issue:5681

    Topics: Anemia, Hemolytic; Antimalarials; Blood Transfusion; Female; Folic Acid; Folic Acid Deficiency; Hema

1969
New concepts in treatment of malignant tertian malaria with cerebral involvement.
    British medical journal, 1971, Mar-27, Volume: 1, Issue:5751

    Topics: Adult; Brain Diseases; Brain Edema; Dexamethasone; Dextrans; Drug Synergism; Heparin; Humans; Malari

1971