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prednisolone and Macrophage Activation Syndrome

prednisolone has been researched along with Macrophage Activation Syndrome in 13 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Macrophage Activation Syndrome: A serious complication of childhood systemic inflammatory disorders that is thought to be caused by excessive activation and proliferation of T-LYMPHOCYTES and MACROPHAGES. It is seen predominantly in children with systemic onset JUVENILE IDIOPATHIC ARTHRITIS.

Research Excerpts

ExcerptRelevanceReference
"We conducted a multi-center cohort study of children in Turkish Pediatric Intensive Care units with hyperferritinemia associated secondary HLH/sepsis/MODS/MAS treated with less immunosuppression (plasma exchange and intravenous immunoglobulin or methyl prednisolone) or with the primary HLH protocol (plasma exchange and dexamethasone or cyclosporine A and/or etoposide)."3.78Hyperferritinemia in the critically ill child with secondary hemophagocytic lymphohistiocytosis/sepsis/multiple organ dysfunction syndrome/macrophage activation syndrome: what is the treatment? ( Bayrakci, B; Carcillo, JA; Citak, A; Demirkol, D; Dursun, O; Erkek, N; Gedik, H; Karabocuoglu, M; Karapinar, B; Kendirli, T; Kesici, S; Koroglu, TF; Yildizdas, D, 2012)
"Thrombocytopenia was seen in 11 patients."1.62Macrophage activation syndrome in children with Kawasaki disease: an experience from a tertiary care hospital in northwest India. ( Gupta, A; Jindal, AK; Johnson, N; Pilania, RK; Prithvi, A; Rawat, A; Singh, S; Suri, D; Vignesh, P, 2021)
"We describe 2 patients with systemic juvenile idiopathic arthritis and macrophage activation syndrome."1.37Rapid and sustained remission of systemic juvenile idiopathic arthritis-associated macrophage activation syndrome through treatment with anakinra and corticosteroids. ( Bruck, N; Gahr, M; Heubner, G; Kabus, M; Pessler, F; Suttorp, M, 2011)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (61.54)24.3611
2020's5 (38.46)2.80

Authors

AuthorsStudies
Kawasaki, T1
Ooka, S1
Mizushima, M1
Nakamura, Y1
Ikeda, H1
Sakurada, T1
Suzuki, S1
Yamazaki, K1
Goto, Y1
Sakurai, K1
Yukitaka, Y1
Kiyokawa, T1
Tonooka, K1
Kunishima, H1
Kawahata, K1
Horiuchi, Y1
Hashimoto, K1
Horikoshi, H1
Sano, A1
Kawamura, Y1
Fujita, N1
Kimata, M1
Ono, Y1
Obuchi, Y1
Makino, A1
Kaneko, M1
Kimura, F1
Itoh, K1
Tanaka, Y1
Goda, K1
Kenzaka, T1
Hoshijima, M1
Yachie, A3
Akita, H1
Shah, K1
Porter, A1
Takhar, G1
Reddy, V1
Pilania, RK1
Jindal, AK2
Johnson, N1
Prithvi, A1
Vignesh, P1
Suri, D2
Rawat, A1
Gupta, A1
Singh, S1
Tulbă, D1
Balea, M1
Băicuş, C1
Aoyama-Maeda, N1
Horino, T1
Ichii, O1
Terada, Y1
Agarwal, A1
Guleria, S1
Singh, MP1
Sharma, S1
Naseem, S1
Ratho, RK1
Shimizu, M2
Kizawa, T1
Kato, R1
Suzuki, T1
Inoue, N1
Tsunoda, S1
Kawano, M1
Matsumura, M1
Bruck, N1
Suttorp, M1
Kabus, M1
Heubner, G1
Gahr, M1
Pessler, F1
John, TM1
Jacob, CN1
Ittycheria, CC1
George, AM1
Jacob, AG1
Subramaniyam, S1
Puthiyaveettil, J1
Jayaprakash, R1
Demirkol, D1
Yildizdas, D1
Bayrakci, B1
Karapinar, B1
Kendirli, T1
Koroglu, TF1
Dursun, O1
Erkek, N1
Gedik, H1
Citak, A1
Kesici, S1
Karabocuoglu, M1
Carcillo, JA1

Reviews

1 review available for prednisolone and Macrophage Activation Syndrome

ArticleYear
Adult-onset Still's disease with macrophage activation syndrome diagnosed and treated based on cytokine profiling: a case-based review.
    Rheumatology international, 2020, Volume: 40, Issue:1

    Topics: Cytokines; Female; Glucocorticoids; Humans; Interleukin-18; Interleukin-6; Macrophage Activation Syn

2020

Other Studies

12 other studies available for prednisolone and Macrophage Activation Syndrome

ArticleYear
COVID-19 and adult-onset Still's disease as part of hyperferritinemic syndromes.
    Modern rheumatology case reports, 2022, 01-07, Volume: 6, Issue:1

    Topics: Adult; Antibodies, Monoclonal, Humanized; COVID-19; COVID-19 Drug Treatment; Ferritins; Humans; Macr

2022
Fulminant elderly adult-onset Still disease effectively treated with tocilizumab and methotrexate: A case report.
    Medicine, 2022, Jul-15, Volume: 101, Issue:28

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Disseminated Intravascular Coagul

2022
Case of using mycophenolate in combination with steroids for concurrent macrophage activation syndrome and lupus flare.
    BMJ case reports, 2020, Apr-07, Volume: 13, Issue:4

    Topics: Adult; Diagnosis, Differential; Drug Therapy, Combination; Enzyme Inhibitors; Female; Glucocorticoid

2020
Macrophage activation syndrome in children with Kawasaki disease: an experience from a tertiary care hospital in northwest India.
    Rheumatology (Oxford, England), 2021, 07-01, Volume: 60, Issue:7

    Topics: Child; Child, Preschool; Coronary Aneurysm; Female; Glucocorticoids; Humans; Immunoglobulins, Intrav

2021
Macrophage activation syndrome at the onset of glucocorticoid-resistant systemic lupus erythematosus: a case report.
    Romanian journal of internal medicine = Revue roumaine de medecine interne, 2018, Mar-01, Volume: 56, Issue:1

    Topics: Adult; Diagnosis, Differential; Drug Resistance; Glucocorticoids; Humans; Immunosuppressive Agents;

2018
Macrophage activation syndrome associated with systemic lupus erythematosus treated successfully with the combination of steroid pulse, immunoglobulin and tacrolimus.
    Romanian journal of internal medicine = Revue roumaine de medecine interne, 2018, Jun-01, Volume: 56, Issue:2

    Topics: Administration, Oral; Adult; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Immunoglobu

2018
Adult-Onset Still Disease and Macrophage Activation Syndrome Following Chikungunya and Hepatitis E Coinfection.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2018, Volume: 24, Issue:7

    Topics: Adolescent; Antirheumatic Agents; Chikungunya Fever; Chikungunya virus; Female; Hepatitis E; Hepatit

2018
Macrophage activation syndrome in neonates born to mothers with adult-onset Still's disease: Perinatal effect of maternal IL-18.
    Clinical immunology (Orlando, Fla.), 2019, Volume: 207

    Topics: Adult; Blood Transfusion; Dexamethasone; Female; Ferritins; Glucocorticoids; Humans; Infant, Newborn

2019
Cytokine profile in adult-onset Still's disease: Comparison with systemic juvenile idiopathic arthritis.
    Clinical immunology (Orlando, Fla.), 2016, Volume: 169

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Arthritis, Juvenile; Child; Child, Prescho

2016
Rapid and sustained remission of systemic juvenile idiopathic arthritis-associated macrophage activation syndrome through treatment with anakinra and corticosteroids.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2011, Volume: 17, Issue:1

    Topics: Antirheumatic Agents; Arthritis, Juvenile; Child; Dexamethasone; Drug Tolerance; Female; Glucocortic

2011
Macrophage activation syndrome following Acinetobacter baumannii sepsis.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2012, Volume: 16, Issue:3

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Adult; Anti-Bacterial Agents; Colistin; Cyclospor

2012
Hyperferritinemia in the critically ill child with secondary hemophagocytic lymphohistiocytosis/sepsis/multiple organ dysfunction syndrome/macrophage activation syndrome: what is the treatment?
    Critical care (London, England), 2012, Dec-12, Volume: 16, Issue:2

    Topics: Adolescent; Antineoplastic Agents, Phytogenic; Child; Child, Preschool; Combined Modality Therapy; C

2012