prednisolone has been researched along with MELAS Syndrome in 3 studies
Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.
MELAS Syndrome: A mitochondrial disorder characterized by focal or generalized seizures, episodes of transient or persistent neurologic dysfunction resembling strokes, and ragged-red fibers on muscle biopsy. Affected individuals tend to be normal at birth through early childhood, then experience growth failure, episodic vomiting, and recurrent cerebral insults resulting in visual loss and hemiparesis. The cortical lesions tend to occur in the parietal and occipital lobes and are not associated with vascular occlusion. VASCULAR HEADACHE is frequently associated and the disorder tends to be familial. (From Joynt, Clinical Neurology, 1992, Ch56, p117)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We here reported the clinical course and therapeutic details of a 16-year-old girl with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) who had had five stroke-like episodes (two episodes were clinically mild, while the three subsequent episodes were severe)." | 7.72 | Beneficial effect of L-arginine for stroke-like episode in MELAS. ( Kubota, M; Momoi-Yoshida, M; Mori, M; Sakakihara, Y; Yamagata, T, 2004) |
| "Therefore, the overlapping syndrome of chronic progressive external ophthalmoplegia in the MELAS syndrome is considered in this case." | 5.29 | CPEO and carnitine deficiency overlapping in MELAS syndrome. ( Chen, HL; Chuang, YH; Hsu, CC; Huang, HL; Jong, HJ; Lee, HC; Pang, CY; Shen, YY; Tsai, JL; Wei, YH, 1995) |
| "We here reported the clinical course and therapeutic details of a 16-year-old girl with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) who had had five stroke-like episodes (two episodes were clinically mild, while the three subsequent episodes were severe)." | 3.72 | Beneficial effect of L-arginine for stroke-like episode in MELAS. ( Kubota, M; Momoi-Yoshida, M; Mori, M; Sakakihara, Y; Yamagata, T, 2004) |
| "Therefore, the overlapping syndrome of chronic progressive external ophthalmoplegia in the MELAS syndrome is considered in this case." | 1.29 | CPEO and carnitine deficiency overlapping in MELAS syndrome. ( Chen, HL; Chuang, YH; Hsu, CC; Huang, HL; Jong, HJ; Lee, HC; Pang, CY; Shen, YY; Tsai, JL; Wei, YH, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Choi, HS | 1 |
| Lee, JH | 1 |
| Lee, SH | 1 |
| Lee, YM | 1 |
| Kubota, M | 1 |
| Sakakihara, Y | 1 |
| Mori, M | 1 |
| Yamagata, T | 1 |
| Momoi-Yoshida, M | 1 |
| Hsu, CC | 1 |
| Chuang, YH | 1 |
| Tsai, JL | 1 |
| Jong, HJ | 1 |
| Shen, YY | 1 |
| Huang, HL | 1 |
| Chen, HL | 1 |
| Lee, HC | 1 |
| Pang, CY | 1 |
| Wei, YH | 1 |
3 other studies available for prednisolone and MELAS Syndrome
| Article | Year |
|---|---|
Avascular necrosis after long-term glucocorticoid treatment in MELAS: a cautionary note.
Topics: Femur Head Necrosis; Glucocorticoids; Humans; Magnetic Resonance Imaging; Male; MELAS Syndrome; Pred | 2018 |
Beneficial effect of L-arginine for stroke-like episode in MELAS.
Topics: Adolescent; Arginine; Brain; Brain Ischemia; Drug Therapy, Combination; Energy Metabolism; Female; G | 2004 |
CPEO and carnitine deficiency overlapping in MELAS syndrome.
Topics: Adult; Atrophy; Biopsy; Brain; Carnitine; Cerebral Cortex; DNA, Mitochondrial; Female; Humans; MELAS | 1995 |