Page last updated: 2024-11-06

prednisolone and Lymphoma, B-Cell

prednisolone has been researched along with Lymphoma, B-Cell in 187 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Lymphoma, B-Cell: A group of heterogeneous lymphoid tumors generally expressing one or more B-cell antigens or representing malignant transformations of B-lymphocytes.

Research Excerpts

ExcerptRelevanceReference
" We have previously described the effectiveness of the R-THP-COP regimen comprising rituximab, cyclophosphamide, pirarubicin, vincristine and prednisolone in patients with diffuse large B-cell lymphoma."9.16A phase II study of rituximab combined with pirarubicin-cyclophosphamide, vincristine and prednisolone regimen as first-line therapy for patients with indolent B-cell lymphoma. ( Fukuno, K; Goto, H; Goto, N; Hara, T; Kanemura, N; Kasahara, S; Kitagawa, J; Moriwaki, H; Sawada, M; Shimizu, M; Takahashi, T; Takami, T; Tsurumi, H; Yamada, T; Yoshikawa, T, 2012)
"To evaluate the efficacy of a combined modality treatment (MACOP-B plus mediastinal radiotherapy) and the advantages of Gallium-67-citrate single-photon emission ((67)GaSPECT) over computed tomography (CT) for restaging in patients with primary mediastinal large B-cell lymphoma (PMLBCL) with sclerosis."9.09Treatment and clinical management of primary mediastinal large B-cell lymphoma with sclerosis: MACOP-B regimen and mediastinal radiotherapy monitored by (67)Gallium scan in 50 patients. ( Ascani, S; Bendandi, M; Magagnoli, M; Mandelli, F; Martelli, M; Martelli, MP; Orcioni, GF; Palombi, F; Pescarmona, E; Pileri, SA; Scaramucci, L; Tura, S; Zinzani, PL, 1999)
"Here we report three cases of hepatitis B virus (HBV) reactivation after cessation of preemptive lamivudine therapy in B-cell lymphoma patients treated with rituximab plus CHOP (R-CHOP)."7.75[Hepatitis B virus reactivation after cessation of prophylactic lamivudine therapy in B-cell lymphoma patients treated with rituximab combined CHOP therapy]. ( Fukai, K; Ise, M; Kojima, H; Kumagai, K; Mimura, N; Sakai, C; Takagi, T; Tsujimura, H; Yokosuka, O, 2009)
"We report a patient with rheumatoid arthritis (RA) who developed malignant lymphoma of the diffuse large B-cell type in the right submandibular region shortly after initiation of oral methotrexate (MTX)."7.72Malignant lymphoma associated with rheumatoid arthritis, developing shortly after initiation of oral methotrexate. ( Gono, T; Hoshi, K; Ikeda, S; Matsuda, M; Shikama, N; Shimojima, Y; Tokuda, T; Yamamoto, K, 2004)
"In this open-label, randomised, phase 3 trial done across 61 centres in Germany, patients aged 18-60 years with newly diagnosed, high-risk (age-adjusted International Prognostic Index [IPI] 2 or 3) aggressive B-cell lymphoma were randomly assigned (1:1, using Pocock minimisation) to eight cycles of conventional chemotherapy (cyclosphosphamide, doxorubicin, vincristine, etoposide, and prednisolone) plus rituximab (R-CHOEP-14) or four cycles of high-dose chemotherapy plus rituximab followed by autologous HSCT (R-MegaCHOEP)."5.41Rituximab plus high-dose chemotherapy (MegaCHOEP) or conventional chemotherapy (CHOEP-14) in young, high-risk patients with aggressive B-cell lymphoma: 10-year follow-up of a randomised, open-label, phase 3 trial. ( Altmann, B; Bentz, M; Borchmann, P; Dreyling, M; Frontzek, F; Glass, B; Haenel, M; Held, G; Horn, H; Kroschinsky, FP; Lenz, G; Loeffler, M; Metzner, B; Nickelsen, M; Ott, G; Rosenwald, A; Schmitz, N; Staiger, AM; Truemper, L; Viardot, A; Ziepert, M, 2021)
"Patients with histologically verified MALT lymphoma undergoing chemotherapy with MCP were evaluated retrospectively."5.32Treatment of extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) with mitoxantrone, chlorambucil and prednisone (MCP). ( Chott, A; Dirisamer, A; Drach, J; Hejna, M; Püspök, A; Raderer, M; Scheithauer, W; Wöhrer, S, 2003)
" We have previously described the effectiveness of the R-THP-COP regimen comprising rituximab, cyclophosphamide, pirarubicin, vincristine and prednisolone in patients with diffuse large B-cell lymphoma."5.16A phase II study of rituximab combined with pirarubicin-cyclophosphamide, vincristine and prednisolone regimen as first-line therapy for patients with indolent B-cell lymphoma. ( Fukuno, K; Goto, H; Goto, N; Hara, T; Kanemura, N; Kasahara, S; Kitagawa, J; Moriwaki, H; Sawada, M; Shimizu, M; Takahashi, T; Takami, T; Tsurumi, H; Yamada, T; Yoshikawa, T, 2012)
"We did an open-label, randomised trial comparing conventional chemotherapy (cyclophosphamide, doxorubicin, vincristine, etoposide, prednisone) and rituximab (R-CHOEP-14) with dose-escalated sequential HDT and rituximab (R-MegaCHOEP) followed by repetitive ASCT in high-risk (age-adjusted International Prognostic Index [IPI] 2 or 3) patients aged 18-60 years with aggressive B-cell lymphoma."5.16Conventional chemotherapy (CHOEP-14) with rituximab or high-dose chemotherapy (MegaCHOEP) with rituximab for young, high-risk patients with aggressive B-cell lymphoma: an open-label, randomised, phase 3 trial (DSHNHL 2002-1). ( Bentz, M; Borchmann, P; Doelken, G; Ehninger, G; Glass, B; Haenel, M; Loeffler, M; Nickelsen, M; Peter, N; Pfreundschuh, M; Rosenwald, A; Ruebe, C; Schmidt, C; Schmitz, N; Truemper, L; Viardot, A; Ziepert, M, 2012)
"To evaluate the efficacy of a combined modality treatment (MACOP-B plus mediastinal radiotherapy) and the advantages of Gallium-67-citrate single-photon emission ((67)GaSPECT) over computed tomography (CT) for restaging in patients with primary mediastinal large B-cell lymphoma (PMLBCL) with sclerosis."5.09Treatment and clinical management of primary mediastinal large B-cell lymphoma with sclerosis: MACOP-B regimen and mediastinal radiotherapy monitored by (67)Gallium scan in 50 patients. ( Ascani, S; Bendandi, M; Magagnoli, M; Mandelli, F; Martelli, M; Martelli, MP; Orcioni, GF; Palombi, F; Pescarmona, E; Pileri, SA; Scaramucci, L; Tura, S; Zinzani, PL, 1999)
"A 55-year-old woman with concurrent active thyroid orbitopathy and B-cell lymphoma developed acute exacerbation of thyroid orbitopathy after receiving Rituximab, cyclophosphamide, hydroxydaunorubicin, Prednisone (R-CHOP) chemotherapy, presenting with subtotal loss of vision and severe eyelid edema."3.88Chemotherapy-induced exacerbations of thyroid orbitopathy in a patient with B-cell lymphoma. ( Croon-de Boer, F; Dalm, VASH; Liu, C; Paridaens, D; van Hagen, PM, 2018)
"Here we report three cases of hepatitis B virus (HBV) reactivation after cessation of preemptive lamivudine therapy in B-cell lymphoma patients treated with rituximab plus CHOP (R-CHOP)."3.75[Hepatitis B virus reactivation after cessation of prophylactic lamivudine therapy in B-cell lymphoma patients treated with rituximab combined CHOP therapy]. ( Fukai, K; Ise, M; Kojima, H; Kumagai, K; Mimura, N; Sakai, C; Takagi, T; Tsujimura, H; Yokosuka, O, 2009)
" She had a history of rheumatoid arthritis (RA) for 26 years, and had been taking methotrexate and prednisolone."3.74[Case of malignant lymphoma associated with rheumatoid arthritis]. ( Kono, T; Noguchi, T; Nohara, J; Sakaguchi, Y; Terada, Y, 2008)
"The patient received oral prednisolone 15 mg daily for polymyalgia rheumatica along with alendronate 70 mg weekly."3.73A case of polymyalgia rheumatica, microscopic polyangiitis, and B-cell lymphoma. ( Chakravarty, K; Hakim, A; Hughes, R; Keat, A; Kuttikat, A, 2006)
"We report a patient with rheumatoid arthritis (RA) who developed malignant lymphoma of the diffuse large B-cell type in the right submandibular region shortly after initiation of oral methotrexate (MTX)."3.72Malignant lymphoma associated with rheumatoid arthritis, developing shortly after initiation of oral methotrexate. ( Gono, T; Hoshi, K; Ikeda, S; Matsuda, M; Shikama, N; Shimojima, Y; Tokuda, T; Yamamoto, K, 2004)
"CHOP-14 with the addition of rhG-CSF is safe and practicable in a large multicentre setting in patients aged 18-75 years."2.71Practicability and acute haematological toxicity of 2- and 3-weekly CHOP and CHOEP chemotherapy for aggressive non-Hodgkin's lymphoma: results from the NHL-B trial of the German High-Grade Non-Hodgkin's Lymphoma Study Group (DSHNHL). ( Bittner, S; Kloess, M; Loeffler, M; Pfreundschuh, M; Reiser, M; Rudolph, C; Schmalenberg, H; Schmits, R; Truemper, L; Wunderlich, A, 2003)
"Isolated gastric varices (IGV) can occur in patients with left-sided portal hypertension resulting from splenic vein occlusion caused by thrombosis or stenosis."2.49Isolated gastric variceal bleeding caused by splenic lymphoma-associated splenic vein occlusion. ( Chang, WK; Chen, BC; Hsieh, TY; Lin, YC; Shih, YL; Wang, HH, 2013)
"However, Wernicke encephalopathy (cerebral Beriberi), a clinical manifestation of thiamine deficiency, has rarely been associated with cancer patients."2.44Wernicke encephalopathy complicating lymphoma therapy: case report and literature review. ( Boniol, S; Boyd, M; Burton, GV; Koreth, R, 2007)
"Acute perforated appendicitis is a very rare initial presentation of appendiceal lymphoma."2.42Primary appendiceal lymphoma presenting as perforated acute appendicitis. ( Fu, TY; Tseng, HH; Wang, JS, 2004)
"Erythema nodosum is the most frequent clinicopathological variant of the panniculitides."2.42[Erythema nodosum association with malignant lymphoma]. ( Griniūte, R; Pileckyte, M, 2003)
" This study aimed to assess the efficacy and toxicity of dose-adjusted CHOP alone or in combination with rituximab (R-CHOP) by examining the stem cell mobilization in NHL patients."1.42Autologous peripheral blood stem cell mobilization following dose-adjusted cyclophosphamide, doxorubicin, vincristine, and prednisolone chemotherapy alone or in combination with rituximab in treating high-risk non-Hodgkin's lymphoma. ( Gui, L; Han, X; He, X; Liu, P; Qin, Y; Shi, Y; Yang, J; Yang, S; Yao, J; Zhang, C; Zhang, S; Zhao, L; Zhou, P; Zhou, S, 2015)
"Thereafter, local recurrence of pyothorax-associated lymphoma (PAL) at the primary site was seen."1.33CD20-negative pyothorax-associated B cell lymphoma. ( Fukuno, K; Kanemura, N; Moriwaki, H; Nishio, M; Okamoto, K; Tanabashi, S; Tsurumi, H, 2005)
"We report a patient in whom sudden hearing loss heralded IVL and propose that the hearing loss may have been the consequence of labyrinthine infarction consequent to the aggregation of malignant cells in the internal auditory artery."1.33Intravascular lymphomatosis presenting with sudden hearing loss. ( Berger, JR; Jones, R; Wilson, D, 2005)
"We examined the efficacy and adverse effects of rituximab with CHOP (cyclophosphamide, doxorubicin, vincristin, prednisone) or THP-COP (pirarubicin, cyclophosphamide, vincristin, prednisone) in previously untreated old-old and extremely old patients with diffuse large B cell lymphoma (DLBCL)."1.33[The efficacy and adverse effects of rituximab with CHOP or THP-COP in old-old and extremely old patients with diffuse large B cell lymphoma]. ( Abe, S; Fujii, H; Iwamoto, T; Kanaya, K; Kikukawa, M; Kiuchi, A; Miyazaki, K; Shin, K, 2006)
"Grade 3 follicular lymphoma (FL3) is thought to have an aggressive clinical course."1.32A significant diffuse component predicts for inferior survival in grade 3 follicular lymphoma, but cytologic subtypes do not predict survival. ( Aoun, P; Armitage, JO; Bierman, PJ; Bociek, RG; Chan, WC; Greiner, TC; Hans, CP; Hock, LM; Lynch, JC; Vose, JM; Weisenburger, DD, 2003)
"We report a case of tracheoesophageal fistula (TEF) secondary to chemotherapy for primary thyroid lymphoma."1.32Tracheoesophageal fistula secondary to chemotherapy for malignant B-cell lymphoma of the thyroid: successful surgical treatment with jejunal interposition and mesenteric patch. ( Arai, W; Hosoya, Y; Hyodo, M; Nagai, H; Nishino, H; Sugawara, Y; Yasuda, Y; Yokoyama, T, 2004)
"Diagnosed as having a testicular tumor by ultrasonography and MRI, he underwent orchiectomy."1.32[Testicular malignant lymphoma: a case report]. ( Iwasawa, T; Kuroda, K; Masuda, E; Matsushima, M; Satou, D; Sawada, Y; Tajima, M; Takeuchi, Y; Yabuki, D, 2003)
"Patients with histologically verified MALT lymphoma undergoing chemotherapy with MCP were evaluated retrospectively."1.32Treatment of extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) with mitoxantrone, chlorambucil and prednisone (MCP). ( Chott, A; Dirisamer, A; Drach, J; Hejna, M; Püspök, A; Raderer, M; Scheithauer, W; Wöhrer, S, 2003)
"The diagnosis of Wegener's Granulomatosis (WG) was formed on the base of clinical features and result of pathologic examination of surgical specimen from the paranasal sinuses."1.31[Diffuse large B-cell lymphoma mimicking Wegener's granulomatosis]. ( Dobkowski, P; Gawryluk, D; Słodkowska, J; Wiatr, E, 2002)
"In this case, congestive heart failure developed even though the total dose of pirarubicin was lower than in previous reports of this complication."1.31[CHF arising after low dose THP-COP chemotherapy in an elderly patient with malignant lymphoma]. ( Doi, N; Fujimoto, S; Hashimoto, T; Matoba-Ueno, K; Nakamura, S; Nishino, T; Shiiki, H; Yamano, S, 2001)
"Multiple brain tumors were found and diagnosed as having B-cell, diffuse large cell type malignant lymphoma."1.30[A case of malignant lymphoma after renal transplantation]. ( Ikeda, K; Inoue, S; Matsuura, O; Murakami, S; Oyama, H; Sugiyama, T; Yamao, K, 1997)
"Pneumonitis is a well recognized side effect of this drug, but occurs at low doses in the treatment of NHL."1.30Two cases of fatal bleomycin pneumonitis complicating the treatment of non-Hodgkin's lymphoma. ( Bloor, AJ; Marcus, RE; Seale, JR, 1998)
"Our case rapidly fell into oliguria and acute renal failure, hence needed hemodialysis."1.30[A case of non-Hodgkin's lymphoma presenting with acute renal failure diagnosed by renal biopsy]. ( Hayashi, H; Inaguma, D; Ishihara, S; Kanoh, T; Kumon, S; Kurata, K; Machida, H; Yaomura, T, 1999)
"A 12-year-old girl suffering from Bloom's syndrome developed B-cell-type lymphoma in the epipharynx."1.28Treatment for B-cell-type lymphoma in a girl associated with Bloom's syndrome. ( Horie, H; Kinugawa, N; Kudoh, F; Miyamoto, S; Okimoto, Y; Oto, S, 1992)
"The initial clinical diagnosis was left testicular tumor."1.28Malignant lymphoma of the testis presenting as primary testicular tumor. ( Kanetake, H; Minami, Y; Nomata, K; Saha, PK; Saito, Y; Sakai, H, 1991)

Research

Studies (187)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's45 (24.06)18.2507
2000's103 (55.08)29.6817
2010's34 (18.18)24.3611
2020's5 (2.67)2.80

Authors

AuthorsStudies
Shimizu, N1
Ngayama, D1
Watanabe, Y2
Yamaguchi, T2
Nakamura, S5
Ohira, M1
Saiki, A1
Onda, H1
Yamaoka, S1
Abe, K2
Nakaseko, C1
Tatsuno, I1
Sawaki, A1
Miyazaki, K2
Yamaguchi, M1
Takeuchi, T1
Kobayashi, K1
Imai, H2
Tawara, I1
Ono, R1
Nosaka, T1
Katayama, N1
Fujita, N1
Ando, M2
Goto, A1
Sakata, M1
Ogata, M1
Usagawa, Y1
Yoshikawa, H2
Yamasue, M1
Komiya, K1
Umeki, K1
Nureki, SI1
Kadota, JI1
Sparks, A1
Woods, JP1
Bienzle, D1
Wood, GA1
Coomber, BL1
Frontzek, F1
Ziepert, M2
Nickelsen, M2
Altmann, B1
Glass, B3
Haenel, M3
Truemper, L4
Held, G1
Bentz, M2
Borchmann, P2
Dreyling, M1
Viardot, A2
Kroschinsky, FP1
Metzner, B1
Staiger, AM1
Horn, H1
Ott, G2
Rosenwald, A2
Loeffler, M5
Lenz, G1
Schmitz, N3
Davies, O1
Szladovits, B1
Polton, G1
Garden, OA1
Leo, C1
Lara-Garcia, A1
Liu, C1
Dalm, VASH1
van Hagen, PM1
Croon-de Boer, F1
Paridaens, D1
Valejo Coelho, MM1
Borges, AS1
Fernandes, C1
Ribeiro, P1
João, A1
Carvalho, R1
Ben Ayed, C1
Laabidi, S1
Said, N1
Afrit, M1
Ben Ahmed, S1
Boussen, H1
Kobayashi, H2
Matsunaga, Y1
Uchiyama, Y1
Nagura, K1
Komatsu, Y1
Chen, BC1
Wang, HH1
Lin, YC1
Shih, YL1
Chang, WK1
Hsieh, TY1
Kanazawa, Y1
Hagiwara, N1
Matsuo, R1
Arakawa, S1
Ago, T1
Kitazono, T1
Sekiguchi, Y1
Shimada, A1
Wakabayashi, M1
Sugimoto, K1
Nakamura, N1
Sawada, T1
Komatsu, N1
Noguchi, M1
Kim, MJ1
Hong, ME1
Maeng, CH1
Jung, HA1
Hong, JY1
Choi, MK1
Kim, SJ2
Ko, YH2
Kim, WS2
Shi, Y1
Zhou, P1
Han, X1
He, X1
Zhou, S1
Liu, P1
Yang, J1
Zhang, C1
Gui, L1
Qin, Y1
Yang, S1
Zhao, L1
Yao, J1
Zhang, S1
Kryachok, IA1
Aleksyk, OM1
Cartron, G1
Hourcade-Potelleret, F1
Morschhauser, F1
Salles, G1
Wenger, M1
Truppel-Hartmann, A1
Carlile, DJ1
Hishikari, K1
Kuwahara, T1
Kimura, S1
Hikita, H1
Takahashi, A1
Isobe, M1
Tsuji, H1
Mochiduki, A1
Hosaka, A1
Yoshizawa, T1
Tamaoka, A1
Vural, F1
Saydam, G1
Cagirgan, S1
Ertekin, B1
Hekimgil, M1
Unal, I1
Soydan, S1
Tombuloglu, M1
Gotoh, M1
Kitahara, T1
Iguchi, T1
Izumi, M1
Mukai, K2
Ohyashiki, K2
Asagi, A1
Miyake, Y1
Yasuhara, H1
Matsumoto, K2
Takahara, M1
Kawai, D1
Kaji, E1
Toyokawa, T1
Onishi, T1
Miyatani, K1
Nakatsu, M1
Visani, G2
Isidori, A2
Inoue, D1
Hamamura, T1
Uehara, T1
Miyoshi, K1
Katsuragi, T1
Takeshita, I2
Hamada, T1
Kabiri, el H1
Kabiri, M1
Doghmi, K1
Chaiwun, B1
Sukhamwang, N1
Ya-In, C1
Shuangshoti, S1
Myung, J1
Kim, B1
Yoon, BW1
Lee, SK1
Sung, JJ1
Chung, CK1
Chang, KH1
Park, SH2
De Zan, G1
Zappulli, V1
Cavicchioli, L1
Di Martino, L1
Ros, E1
Conforto, G1
Castagnaro, M1
Elkadi, D1
Wiernik, PH1
Tong, TR1
Mimura, N1
Tsujimura, H2
Ise, M1
Sakai, C2
Kojima, H1
Fukai, K1
Yokosuka, O1
Takagi, T2
Kumagai, K2
Montineri, A1
Nigro, L1
Chiarenza, A1
Larocca, L1
La Rosa, R1
Iacobello, C1
Di Raimondo, F1
Fatuzzo, F1
Tauro, S1
Cochrane, L1
Lauritzsen, GF1
Baker, L1
Delabie, J1
Roberts, C1
Mahendra, P1
Holte, H1
Yamashita, T1
Sakaura, H1
Oshima, K1
Iwasaki, M1
Babu, K1
Murthy, KR1
Krishnakumar, S1
Kim, BJ1
Park, HR1
Roh, HJ1
Jeong, DS1
Kim, BS1
Park, KW1
Cho, SC1
So, YT1
Oh, SY1
Itoh, S1
Okada, N1
Wakasa, T1
Tsudo, M1
Shintaku, M1
Kimura, T1
Horiguchi, Y1
Rieger, M1
Österborg, A1
Pettengell, R1
White, D1
Gill, D1
Walewski, J1
Kuhnt, E1
Pfreundschuh, M4
Ho, AD1
Giard, C1
Avenel-Audran, M1
Croué, A1
Verret, JL1
Martin, L1
Riihijärvi, S1
Taskinen, M1
Jerkeman, M1
Leppä, S1
Thomas, A1
Kong, J1
Eisenberg, R1
Merli, F1
Angrilli, F1
Ferrara, F1
Alesiani, F1
Bamrolia, N1
Yadava, U1
Anand, A1
Chaudhuri, Z1
Tsurumi, H2
Hara, T1
Goto, N1
Kitagawa, J1
Kanemura, N2
Yoshikawa, T1
Kasahara, S1
Goto, H1
Fukuno, K2
Yamada, T1
Sawada, M1
Shimizu, M1
Takahashi, T1
Takami, T1
Moriwaki, H2
Zeynalova, S1
Kaiser, U1
Cavallin-Stahl, E1
Wolf, M1
Ganzenmueller, T1
Karaguelle, D1
Schmitt, C1
Puppe, W1
Stachan-Kunstyr, R1
Bronzlik, P1
Sauerbrei, A1
Wegner, F1
Heim, A1
Ahn, JY1
Seo, YH1
Park, PW1
Kim, KH1
Park, MJ1
Jeong, JH1
Song, YH1
Hou, Y1
Wang, HQ2
Ba, Y1
Jedliński, I1
Jamrozek-Jedlińska, M1
Bugajski, P1
Pyda, M1
Poprawski, K1
Schmidt, C1
Peter, N1
Ehninger, G1
Doelken, G1
Ruebe, C1
Pranesh, N1
Gawryluk, D1
Słodkowska, J1
Dobkowski, P1
Wiatr, E1
Hans, CP1
Weisenburger, DD1
Vose, JM1
Hock, LM1
Lynch, JC1
Aoun, P1
Greiner, TC1
Chan, WC1
Bociek, RG1
Bierman, PJ1
Armitage, JO1
Mottl, H1
Bajciova, V1
Nemec, J1
Al Shemmari, S1
Al Awadi, S1
Mounier, N1
Briere, J1
Gisselbrecht, C2
Emile, JF1
Lederlin, P1
Sebban, C1
Berger, F2
Bosly, A1
Morel, P1
Tilly, H1
Bouabdallah, R1
Reyes, F1
Gaulard, P1
Coiffier, B2
Takauchi, K1
Kono, H1
Ito, T1
Zaima, K1
Okumoto, S1
Au, WY1
Ma, SK1
Wan, TS1
Wang, EP1
Lau, TC1
Kwong, YL1
Kawakami, K1
Kadowaki, S1
Pileckyte, M1
Griniūte, R1
Wunderlich, A1
Kloess, M1
Reiser, M1
Rudolph, C1
Bittner, S1
Schmalenberg, H1
Schmits, R1
Kang, SM1
Rim, SJ1
Chang, HJ1
Choi, D1
Cho, SY1
Cho, SH1
Chung, N1
Daum, S1
Ullrich, R1
Heise, W1
Dederke, B1
Foss, HD1
Stein, H1
Thiel, E1
Zeitz, M1
Riecken, EO1
Oshiro, A1
Nagasaki, A1
Nakachi, A1
Uchima, N1
Hasegawa, H1
Nakazato, T1
Nakamoto, M2
Kinjo, N1
Kinjo, F2
Taira, N1
Masuda, M1
Takasu, N1
Sathiapalan, RK1
Hainau, B1
Al-Mane, K1
Belgaumi, AF1
Motegi, S1
Nishizaki, Y1
Muramatsu, C1
Nakamura, H2
Kobayashi, F1
Shiozawa, H1
Kamochi, J1
Itakura, M1
Shibuya, M1
Ogawa, T1
Matsuzaki, S1
Kojima, M1
Tanaka, H3
Yamane, Y1
Sugihara, S1
Masawa, N1
Wöhrer, S1
Drach, J1
Hejna, M1
Scheithauer, W1
Dirisamer, A1
Püspök, A1
Chott, A1
Raderer, M1
Nuss, D1
Addicks, K1
Lackner, K1
Nakane, T1
Yamane, T1
Shibata, H1
Aoyama, Y1
Hasegawa, T1
Sakamoto, C1
Nakamae, H1
Terada, Y3
Ohta, K2
Hino, M1
Takeuchi, Y1
Sawada, Y1
Yabuki, D1
Masuda, E1
Satou, D1
Iwasawa, T1
Kuroda, K1
Tajima, M1
Matsushima, M1
Uchino, K1
Sameshima, H1
Miyamoto, T1
Iino, T1
Kato, K2
Henzan, H1
Aoki, K1
Nagafuji, K1
Gondo, H1
Harada, M1
Gono, T1
Shimojima, Y1
Hoshi, K1
Yamamoto, K2
Tokuda, T1
Shikama, N1
Matsuda, M1
Ikeda, S1
Gergely, L1
Aleksza, M1
Váróczy, L1
Ponyi, A1
Sipka, S1
Illés, A1
Szegedi, G1
Sekiguchi, N1
Nishimoto, J1
Tanimoto, K1
Kusumoto, S1
Onishi, Y1
Watanabe, T3
Kobayashi, Y2
Asamura, H1
Kagami, Y2
Matsuno, Y1
Tobinai, K2
Hosoya, Y1
Yokoyama, T1
Arai, W1
Hyodo, M1
Nishino, H1
Sugawara, Y1
Yasuda, Y1
Nagai, H1
Nagashima, O1
Takahashi, K1
Sato, K1
Suzuki, T2
Fukuchi, Y1
Isobe, Y1
Oshimi, K1
Masada, T1
Matsumoto, Y1
Kawai, N1
Tamiya, T1
Nagao, S1
Schneider, T1
Tóth, E1
Molnár, Z1
Várady, E1
Deák, B1
Horváth, A1
Horváth, GI1
Eid, H1
Schneider, K1
Lovey, J1
Keresztes, S1
Esik, O1
Lengyel, Z1
Rosta, A1
Ohta, M1
Matsuoka, S1
Ikeda, K2
Fu, TY1
Wang, JS1
Tseng, HH1
Nishio, M1
Tanabashi, S1
Okamoto, K1
Berger, JR1
Jones, R1
Wilson, D2
Ohkubo, H1
Yoshida, T1
Takaku, T1
Katagiri, T1
Paku, J1
Kasuga, I1
Minemura, K1
Gotoh, A1
Serizawa, H1
Burton, C1
Djakovic, A1
Zollner, U1
Vordermark, D1
Dietl, J1
Bogle, MA1
Riddle, CC1
Triana, EM1
Jones, D1
Duvic, M1
Le, K1
Lim, A1
Bullpitt, P1
Wood, G1
Miyahara, T1
Oyabul, Y1
Hayashi, T2
Shimizu, S1
Matsuoka, K1
Avilés, A1
Neri, N1
Delgado, S1
Pérez, F1
Nambo, MJ1
Cleto, S1
Talavera, A1
Huerta-Guzmán, J1
Takenaka, S1
Mitsudo, K1
Inoue, K1
Goto, T1
Kadota, K1
Fujii, S1
Yamamoto, H1
Fuku, Y1
Hirono, A1
Taba, M1
Ikeda, A1
Kojima, Y1
Maekawa, J1
Maekawa, S1
Takahashi, N2
Saeki, H1
Nakamura, Y2
Oonishi, T1
Ueda, N1
Lin, TY1
Zhang, HY1
Huang, Y1
Guan, ZZ1
Shen, T1
Shi, YK1
Zhu, J1
Ke, XY1
Shen, ZX1
Yu, SY1
Liu, T1
Shi, XL1
Kambayashi, T1
Ono, N1
Otrock, ZK1
Shamseddine, AI1
Taher, AT1
Sakai, R1
Kanamori, H1
Ishigatsubo, Y1
Yoshino, S1
Matsumoto, T1
Konomi, H1
Hirahashi, M1
Yao, T1
Iida, M1
Shirao, S1
Kuroda, H1
Kida, M1
Watanabe, H1
Matsunaga, T1
Niitsu, Y1
Konuma, Y1
Hirayama, Y1
Kohda, K1
Ogura, M1
Morishima, Y1
Itoh, K1
Igarashi, T1
Hotta, T1
Kinoshita, T1
Ohashi, Y1
Mori, S2
Terauchi, T1
Avanzi, GC1
Castello, L1
Sainaghi, PP1
Bergamasco, L1
Boldorini, R1
Bartoli, E1
Kikukawa, M1
Kiuchi, A1
Abe, S1
Fujii, H1
Kanaya, K1
Shin, K1
Iwamoto, T3
Adde, M1
Enblad, G1
Hagberg, H1
Sundström, C1
Laurell, A1
Kubota, Y2
Hokama, A1
Fujita, J1
Laack, NN1
Ballman, KV1
Brown, PB1
O'Neill, BP1
Aydin, E1
Akdoğan, MV1
Yerli, H1
Ozdemir, BH1
Demirhan, B1
Kundranda, MN1
Daw, HA1
Lee, J1
Kim, K1
Ahn, JS1
Jung, CW1
Lim, HY1
Kang, WK1
Park, K1
Kim, YH1
Park, C1
Yoon, SH1
Lee, WY1
Chun, HK1
Bouzani, M1
Karmiris, T1
Rontogianni, D2
Delimpassi, S1
Apostolidis, J1
Mpakiri, M1
Nikiforakis, E1
Bernatsky, S1
Ramsey-Goldman, R1
Lachance, S1
Pineau, CA1
Clarke, AE1
Odawara, J1
Asada, N1
Aoki, T1
Yamakura, M1
Takeuchi, M1
Ohuchi, T1
Matsue, K1
Kuttikat, A1
Keat, A1
Hughes, R1
Hakim, A1
Chakravarty, K1
Sugimoto, T1
Matano, S1
Nishijima, H1
Kakuta, K1
Inamura, K1
Okamura, T1
Munemoto, S1
Satoh, S1
Ishii, A1
Rimsza, LM1
Farinha, P1
Fuchs, DA1
Masoudi, H1
Connors, JM1
Gascoyne, RD1
Takahashi, H1
Kagawa, R1
Takeda, R1
Sakata, S1
Yamamoto, M1
Nishizaki, D1
Takamatsu, T1
Iwasa, Y1
Kim, DH1
Baek, JH1
Chae, YS1
Kim, YK1
Kim, HJ1
Park, YH1
Song, HS1
Chung, JS1
Hyun, MS1
Sohn, SK1
Boniol, S1
Boyd, M1
Koreth, R1
Burton, GV1
Ekmekci, TR1
Koslu, A1
Sakiz, D1
Barutcuoglu, B1
Sumi, M1
Ichikawa, N1
Shimizu, I1
Yotsumoto, M1
Ueno, M1
Akinyemi, E1
Mai, L1
Matin, A1
Maini, A1
Fujiwara, T1
Ishizawa, K1
Kohata, K1
Yamamoto, J1
Yamada, MF1
Kameoka, J1
Ichinohasama, R1
Harigae, H1
Sahni, C1
Desai, S1
Ohye, H1
Fukata, S1
Hirokawa, M2
Noguchi, T1
Nohara, J1
Sakaguchi, Y1
Kono, T1
Falini, B1
Venturi, S1
Martélli, M2
Santucci, A1
Pileri, S1
Pescarmona, E2
Giovannini, M1
Mazza, P1
Martelli, MF1
Pasqualucci, L1
Saito, S1
Hayashi, K1
Ohnoshi, T1
Kawashima, K1
Matsutomo, S1
Tagawa, S1
Mizuta, J1
Tada, A1
Ueno, K1
Kimura, I1
Nagatani, T1
Baba, N1
Nakajima, H1
Graziano, F1
Cellerino, R1
Menestrina, F1
Nicoli, N1
Gramazio, A1
Latini, L1
Piga, A1
Kalra, PA1
Wood, GN1
O'Donoghue, DJ1
Mamtora, H1
Routledge, R1
Armstrong, G1
Sinnott, PJ1
Jos, V1
Johnson, RW1
Waldek, S1
Zanker, B1
Schirmacher, P1
Köhler, H1
Miyake, O1
Tsujihata, M1
Itoh, H2
Wakatsuki, A1
Itatani, H2
Morozumi, M1
Takasu, H1
Okada, M1
Onizuka, T1
Satou, S1
Koike, M1
Ishiyama, T1
Tomoyasu, S1
Tsuruoka, N1
Ohta, H1
Fujisawa, R1
Yamaguchi, A1
Tashiro, T1
Garrett, TJ1
Chadburn, A1
Barr, ML1
Drusin, RE1
Chen, JM1
Schulman, LL1
Smith, CR1
Reison, DS1
Rose, EA1
Michler, RE1
Hattenhauer, MG1
Pach, JM1
Sasai, K1
Yamabe, H1
Haga, H1
Tsutsui, K1
Dodo, Y1
Ishigaki, T1
Shibamoto, Y1
Abe, M1
Fujikawa, I1
Tei, T1
Yagasaki, F1
Nagata, K1
Hamaguchi, H1
Miyake, S1
Goldwasser, F1
Pico, JL1
Cerrina, J1
Fernandez, H1
Pons, JC1
Cosset, JM1
Hayat, M1
Tanaka, S1
Sawada, N1
Kamio, M1
Mochizuki, T1
Jacobs, U1
Niese, D1
Brensing, KA1
Eis-Hübinger, A1
Buszello, H1
Klehr, HU1
Kubo, M1
Koga, M1
Fujii, T1
Kaneko, T1
Yamashita, K1
Kokubu, T1
Gianni, AM1
Bregni, M1
Siena, S1
Brambilla, C1
Di Nicola, M1
Lombardi, F1
Gandola, L1
Tarella, C1
Pileri, A1
Ravagnani, F1
Valagussa, P1
Bonadonna, G1
Satoh, T1
Tsushima, K1
Hizawa, Y1
Nakui, Y1
Itoh, J1
Tamura, Y1
Saitoh, S1
Taka-mi, H1
Munakata, A1
Kawamura, S1
Kuwahara, Y1
Hibi, H1
Yanaoka, Y1
Okishio, N1
Hoshinaga, K1
Naide, Y1
Kasahara, M1
Oyama, H1
Yamao, K1
Sugiyama, T1
Matsuura, O1
Murakami, S1
Inoue, S2
Ono, H1
Yokozeki, H1
Katayama, I1
Nishioka, K1
Kawabata, Y1
Horiuchi, T1
Hatakeyama, T1
Saito, K1
Kume, M2
Nimura, T1
Nishinari, T1
Miura, AB1
Creatsas, GK1
Hassan, EA1
Deligeoroglou, EK1
Markaki, SG1
Michalas, SP1
Nonaka, Y1
Nomura, T1
Ogawa, M1
Bloor, AJ1
Seale, JR1
Marcus, RE1
Nishida, S1
Kuroko, K1
Hoshino, T1
Shirai, C1
Yamanouchi, J1
Okada, T1
Hasegawa, A1
Iwasaki, H1
Hirota, Y1
Yokota, E1
Matsumoto, I1
Fierro, MT1
Quaglino, P1
Savoia, P1
Verrone, A1
Bernengo, MG1
Yaomura, T1
Hayashi, H1
Kanoh, T1
Kurata, K1
Ishihara, S1
Machida, H1
Inaguma, D1
Kumon, S1
Nagatsuma, K1
Tanomogi, H1
Hasegawa, S1
Shimizu, K1
Zinzani, PL1
Magagnoli, M1
Scaramucci, L1
Palombi, F1
Bendandi, M1
Martelli, MP1
Ascani, S1
Orcioni, GF1
Pileri, SA1
Mandelli, F1
Tura, S1
Shinbo, H1
Nakanishi, T1
Suzuki, K2
Fujita, K1
Hertzberg, MS1
Schifter, M1
Sullivan, J1
Stapleton, K1
Taura, Y1
Yamazaki, H1
Katou, T1
Gabryś, K1
Kacprzak, G1
Wakamoto, H1
Miyazaki, H1
Tomita, H1
Ishiyama, N1
Várkonyi, J1
Zalatnai, A1
Timár, J1
Matolcsi, A1
Falus, A1
Bencsáth, M1
László, V1
Pócsik, E1
Kotlán, B1
Császár, A1
Sai, S1
Murase, T1
Vlasveld, LT1
Ermens, AA1
Sonnenberg, AA1
Pauwels, P1
Iwahashi, M1
Iida, S1
Sako, S1
Kikuchi, H1
Otsuka, E1
Nasu, M1
Lebel, E1
Itzchaki, M1
Munakata, S1
Hirano, S1
Yoshiyama, Y1
Koizumi, M1
Kobayasi, T1
Hattori, T1
McLaughlin, P1
Matsuda, T1
Okihama, Y1
Egami, K1
Wada, M1
Yoshioka, M1
Maeda, S1
Onda, M1
Cavalot, AL1
Preti, G1
Vione, N1
Nazionale, G1
Palonta, F1
Fadda, GL1
Matoba-Ueno, K1
Fujimoto, S1
Doi, N1
Nishino, T1
Yamano, S1
Shiiki, H1
Hashimoto, T1
Baba, K1
Yajima, M1
Minagawa, N1
Kazama, A1
Hirayama, K1
Nakamura, T1
Fukazawa, A1
Ohata, K1
Sunayama, K1
Kashiwabara, H1
Maruyama, K1
Konno, H1
Miura, K1
Tsirigotis, P1
Economopoulos, T1
Dervenoulas, J1
Papageorgiou, E1
Bollas, G1
Mantzios, G1
Kalantzis, D1
Koumarianou, A1
Raptis, S1
Siemens, HJ1
Gerke, P1
Steinhoff, J1
Roth-Isigkeit, A1
Wagner, K1
Brückner, S1
Yanagiya, N1
Nakae, H1
Chubachi, A1
Miura, I1
Kollmar, O1
Becker, S1
Schilling, MK1
Maurer, CA1
McCluggage, WG1
Wright, GD1
Okumoto, T1
Tomiyama, K1
Ino, H1
Kanaya, Y1
Maruyama, S1
Otani, J1
Yokoyama, N1
Soda, M1
Wada, S1
Kitamura, H1
Matsuura, Y1
Katayama, Y1
Ohkawa, H1
Kugai, N1
Motoyoshi, K1
Fuse, Y1
Nagata, N1
Kumagai, T1
Enomoto, K1
Maebou, A1
Hara, H1
Yoshimoto, T1
Hirao, F1
Utsunomiya, M1
Takatera, H1
Tsujimura, T1
Wong, RC1
Harrison, P1
Oto, S1
Miyamoto, S1
Kudoh, F1
Horie, H1
Kinugawa, N1
Okimoto, Y1
Brousse, N1
Peuchmaur, M1
Bryon, PA1
Diebold, J1
Kwak, LW1
Wilson, M1
Weiss, LM1
Doggett, R1
Dorfman, RF1
Warnke, RA1
Horning, SJ1
Saha, PK1
Sakai, H1
Nomata, K1
Minami, Y1
Kanetake, H1
Saito, Y1
Shimada, K1
Sato, M1
Haruyama, S1
Ichikawa, T1
Aono, G1
Ohara, T1
Ando, Y1
Abe, R1
Nozawa, Y1
Wakasa, H1
Williams, RE1
Seywright, MM1
Lever, R1
Lucie, NP1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Phase III Study to Compare Conventional Chemotherapy (CHOEP-14) + Rituximab vs High-dose Chemotherapy Followed by Autologous Stem Cell Transplantation (Mega-CHOEP-21) + Rituximab in Younger Patients With Aggressive NHL[NCT00129090]Phase 3450 participants (Actual)Interventional2003-03-31Completed
An Open-Label, Multi-Centre, Randomised, Phase Ib Study to Investigate the Safety and Efficacy of RO5072759 Given in Combination With CHOP, FC or Bendamustine Chemotherapy in Patients With CD20+ B-Cell Follicular Non-Hodgkin's Lymphoma[NCT00825149]Phase 1137 participants (Actual)Interventional2009-02-28Completed
An Open-label, Multicentre, Nonrandomized, Dose-escalating Phase I/II Study, With a Randomized Phase II Part, to Investigate the Safety and Tolerability of RO5072759 Given as Monotherapy in Patients With CD20+ Malignant Disease.[NCT00517530]Phase 1/Phase 2134 participants (Actual)Interventional2007-09-30Completed
Burkimab:Study Multicenter of Optimization of the Treatment of LLA-B and the Burkitt's Lymphoma in Adult Patients (From 15 Years Old)[NCT00388193]Phase 220 participants (Anticipated)Interventional2006-08-31Completed
A Phase II Trial of Irinotecan in Recurrent Glioma[NCT00003134]Phase 264 participants (Actual)Interventional1998-01-31Completed
Primary Central Nervous System Non-Hodgkins's Lymphoma (PCNSL): A Phase II Clinical Trial of Radiation Therapy and High Dose Corticosteroids for Elderly Patients (70 Years of Age and Older)[NCT00003278]Phase 228 participants (Actual)Interventional1998-03-31Completed
Retrospective Multicenter International Study on Prognostic Factors, Management And Outcome Of Primary Mediastinal Large B-Cell Lymphoma (PMLBCL) Patients With Central Nervous System (CNS) Involvement[NCT06024694]45 participants (Anticipated)Observational2022-06-10Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Area Under the Concentration-time Curve of Obinutuzumab Administered on Day 1 of Cycle 1 in Phase I of the Study

Blood samples were taken on Day 1 (pre-infusion, end of infusion, 3-6 hours post-infusion) of Cycle 1. Nonlinear mixed-effects modeling (with NONMEM software) was used to analyze the pooled samples for dose-concentration-time data of obinutuzumab. (NCT00517530)
Timeframe: Day 1 of Cycle 1

Interventionµm/ml*day (Geometric Mean)
400 mg - Phase I, NHL459
800 mg - Phase I, NHL993
1200 mg - Phase I, NHL1057
2000 mg - Phase I, NHL146

Duration of Response by Disease Type in Phase II of the Study

Duration of complete response was defined as the time from the first complete or partial response until disease progression (PD) or death, whichever occurred first. For non-Hodgkin's lymphoma participants, PD was defined as >= 50% increase from nadir in the sum of the products of the greatest diameters (SPD) of any previously identified abnormal node for participants with a partial response or non-responders or the appearance of any new lesion during or at the end of therapy. For chronic lymphocytic leukemia participants, PD was defined as: (1) A >= 50% increase from nadir in the SPD of any previously involved nodes, or in a single involved node, or the size of other lesions (eg, splenic or hepatic nodules); a lymph node with a short axis of < 1.0 cm must increase by >= 50% and to a size of 1.5×1.5 cm or > 1.5 cm in the longest axis. (2) Appearance of any new lesion > 1 cm in the short axis. (4) A new site that is PET-positive with histological confirmation. (NCT00517530)
Timeframe: by the end of the follow-up period in Phase II of the study (within 3 years, 4 months)

Interventiondays (Median)
Phase II, iNHL523
Phase II, aNHL298
Phase II, CLL272.5

Participants With Event-Free Survival (EFS) in Phase II of the Study

EFS is defined as the time from start of treatment to disease progression/relapse, death or, in case of early withdrawal from the treatment period, the (end) date of last dose, whatever comes first. (NCT00517530)
Timeframe: by the end of the follow-up period in Phase II of the study (within 3 years, 4 months)

Interventionparticipants (Number)
400/400 mg - Phase II, iNHL5
1600/800 mg - Phase II, iNHL6
400/400 mg - Phase II, aNHL2
1600/800 mg - Phase II, aNHL3
1000/1000 mg - Phase II, CLL4

Percentage of Participants Who Experienced a Dose-limiting Toxicity in Phase I of the Study

Dose-limiting toxicities were defined as obinutuzumab-related adverse events occurring within the first 28 days of each administration of obinutuzumab, with the exception of B-cell depletion and lymphopenia which are expected outcomes of treatment with obinutuzumab. (NCT00517530)
Timeframe: Baseline to 28 days after the last infusion of obinutuzumab (up to 6 months)

Interventionpercentage of participants (Number)
50/100 mg - Phase I, NHL0
100/200 mg - Phase I, NHL0
200/400 mg - Phase I, NHL0
400/800 mg - Phase I, NHL0
800/1200 mg - Phase I, NHL0
1200/2000 mg - Phase I, NHL0
1600/800 mg - Phase I, NHL0
400/800 mg - Phase I, CLL0
800/1200 mg - Phase I, CLL0
1200/2000 mg - Phase I, CLL0
1000/1000 mg - Phase I, CLL0

Percentage of Participants With Best Overall Response in Phase II of the Study

Best overall response (BOR) was defined as the percentage of participants with a complete response (CR) or partial response (PR) (NCT00517530)
Timeframe: by Cutoff Date: 31 March 2012 (within 3 years, 4 months)

Interventionpercentage of participants (Number)
400/400 mg - Phase II, iNHL33.3
1600/800 mg - Phase II, iNHL63.6
400/400 mg - Phase II, aNHL23.8
1600/800 mg - Phase II, aNHL36.8
1000/1000 mg - Phase II, CLL30.0

Percentage of Participants With Partial Response (PR) in Phase II of the Study

A PR was defined as a >=50% decrease in SPD of the 6 largest nodes or nodal masses; no increase in size of other nodes, liver, or spleen; regression of splenic and hepatic nodules by >=50% in their SPD or, for single nodules, in the long axis (CLL only); and no new disease sites. (NCT00517530)
Timeframe: by Cutoff Date: 31 March 2012 (within 3 years, 4 months)

Interventionpercentage of participants (Number)
400/400 mg - Phase II, iNHL22.2
1600/800 mg - Phase II, iNHL40.9
400/400 mg - Phase II, aNHL9.5
1600/800 mg - Phase II, aNHL21.1
1000/1000 mg - Phase II, CLL25.0

Progression-free Survival (PFS) in Phase II of the Study

PFS was defined as the time from start of treatment to disease progression (PD) or death due to any cause, whichever occurred first. For non-Hodgkin's lymphoma participants, PD was defined as >= 50% increase from nadir in the sum of the products of the greatest diameters (SPD) of any previously identified abnormal node for participants with a partial response or non-responders or the appearance of any new lesion during or at the end of therapy. For chronic lymphocytic leukemia participants, PD was defined as: (1) A >= 50% increase from nadir in the SPD of any previously involved nodes, or in a single involved node, or the size of other lesions (eg, splenic or hepatic nodules); a lymph node with a short axis of < 1.0 cm must increase by >= 50% and to a size of 1.5×1.5 cm or > 1.5 cm in the longest axis. (2) Appearance of any new lesion > 1 cm in the short axis. (4) A new site that is positron emission tomography (PET)-positive with histological confirmation. (NCT00517530)
Timeframe: by the end of the follow-up period in Phase II of the study (within 3 years, 4 months)

Interventiondays (Median)
400/400 mg - Phase II, iNHL182
1600/800 mg - Phase II, iNHL361
400/400 mg - Phase II, aNHL78
1600/800 mg - Phase II, aNHL83
1000/1000 mg - Phase II, CLL324

Maximum Plasma Concentration (Cmax) of Obinutuzumab in CLL Patients

(NCT00517530)
Timeframe: at Cycle 1 Day 1, Cycle 1 Day 8 and Cycle 8 (over 168 days)

,,,
Interventionmicrograms/mL (Geometric Mean)
Cycle 1 Day 1 (n=3,3,3,0)Cycle 1 Day 8 (n=0,0,3,3)Cycle 8 (n=3,3,3,4)
1200 mg - Phase I, CLL307437741
2000 mg - Phase I, CLLNA7351730
400 mg - Phase I, CLL216NA485
800 mg - Phase I, CLL210NA573

Maximum Plasma Concentration (Cmax) of Obinutuzumab in NHL Participants

Obinutuzumab serum pharmacokinetic (PK) parameters in NHL participants following ascending doses. (NCT00517530)
Timeframe: at Cycle 1 Day 1, Cycle 1 Day 8 and Cycle 8 (over 168 days)

,,,
Interventionµm/ml*day (Geometric Mean)
Cycle 1 Day 1 (n=4,6,6,0)Cycle 1 Day 8 (n=0,4,6,6)Cycle 8 (n=0,5,5,5)
1200 mg - Phase I, NHL3074491070
2000 mg - Phase I, NHLNA7141380
400 mg - Phase I, NHL134NANA
800 mg - Phase I, NHL234367698

Percentage of Participants With Complete Response (CR/CRu/CRi) in Phase II of the Study

A complete response was defined as the disappearance of all evidence of disease (NHL) and symptoms; normalization of biochemical abnormalities (NHL); regression of lymph nodes and nodal masses to normal size; decrease of nodes in the sum of the products of the greatest diameters (SPD); regression in size of the spleen and/or liver, should not be palpable, and disappearance of nodules related to lymphoma (CLL). Complete/unconfirmed (CRu) response includes NHL patients with one or more of the following: 1) a residual lymph node mass greater than 1.5 cm in greatest transverse diameter that has regressed by more than 75% in the SPD; 2) Indeterminate bone marrow (increased number or size of aggregates without cytologic or architectural atypia). Complete Response with Incomplete Bone Marrow Recovery (CRi) was measured only in patients with CLL. (NCT00517530)
Timeframe: by Cutoff Date: 31 March 2012 (within 3 years, 4 months)

,,,,
Interventionpercentage of participants (Number)
CRCRuCRi
1000/1000 mg - Phase II, CLL5.0NA0.0
1600/800 mg - Phase II, aNHL15.80.0NA
1600/800 mg - Phase II, iNHL13.69.1NA
400/400 mg - Phase II, aNHL9.54.8NA
400/400 mg - Phase II, iNHL5.65.6NA

Percentage of Retreated Participants With Response

Patients who might benefit from retreatment were allowed to be treated again at the request of the investigator. (NCT00517530)
Timeframe: by Cutoff Date: 25 November 2013 (within 4 years, 2 months)

Interventionpercentage of participants (Number)
Best overall responseComplete responsePartial response
Retreated Participants622338

Pharmacodynamics: Participants With Peripheral B-cell Recovery After Having Had Depletion at End of Treatment During Phase II of the Study

B-cell depletion was defined in two ways: definition 1 - decrease below 5% baseline level and definition 2 - decrease below 0.04 x 109/L. B-cell recovery was defined in two ways: definition 1 - return to at least 50% of baseline level and definition 2 - return to at least 0.08 x 109/L. (NCT00517530)
Timeframe: by the end of Phase II (within 3 years, 4 months)

,,,,
Interventionparticipants (Number)
within 6 months (n=11,19,11,12,13)within 9 months (n=8,17,6,5,10)within 12 months (n=5,16,4,5,9)within 18 months (n=4,13,3,3,8)within 24 months (n=3,10,2,3,5)after 24 months (n=3,4,1,2,0)
1000/1000 mg - Phase II, CLL303220
1600/800 mg - Phase II, aNHL010101
1600/800 mg - Phase II, iNHL002120
400/400 mg - Phase II, aNHL001010
400/400 mg - Phase II, iNHL000021

Reviews

18 reviews available for prednisolone and Lymphoma, B-Cell

ArticleYear
Isolated gastric variceal bleeding caused by splenic lymphoma-associated splenic vein occlusion.
    World journal of gastroenterology, 2013, Oct-28, Volume: 19, Issue:40

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Constriction, Pathologic; Cycl

2013
Intravascular large B-cell lymphoma with pontine involvement successfully treated with R-CHOP therapy and intrathecal administration: a case report and review of literature.
    International journal of clinical and experimental pathology, 2014, Volume: 7, Issue:6

    Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Brain Neopla

2014
Primary cutaneous B-cell lymphoma: report of eight cases and review of the literature.
    International journal of dermatology, 2008, Volume: 47, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Comb

2008
Nonpegylated liposomal doxorubicin in the treatment of B-cell non-Hodgkin's lymphoma: where we stand.
    Expert review of anticancer therapy, 2009, Volume: 9, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Do

2009
[Erythema nodosum association with malignant lymphoma].
    Medicina (Kaunas, Lithuania), 2003, Volume: 39, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Cyclophosphamide; Diagnosis, Dif

2003
[Case of malignant lymphoma arising from the posterior mediastinum, with pleural effusion].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2004, Volume: 42, Issue:8

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antigens, CD20; Antineoplastic

2004
Primary appendiceal lymphoma presenting as perforated acute appendicitis.
    Journal of the Chinese Medical Association : JCMA, 2004, Volume: 67, Issue:12

    Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Appendi

2004
Wernicke encephalopathy complicating lymphoma therapy: case report and literature review.
    Southern medical journal, 2007, Volume: 100, Issue:7

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy

2007
[Malignant lymphoma of the thyroid].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Volume: 65, Issue:11

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy

2007
[Primary malignant lymphoma of the urinary bladder].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1994, Volume: 85, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Hu

1994
[Primary non-Hodgkin lymphoma of the prostate: a case report].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1993, Volume: 84, Issue:11

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cyclophosphamide; Dau

1993
[Malignant lymphoma of the penis: report of two cases].
    Hinyokika kiyo. Acta urologica Japonica, 1997, Volume: 43, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Doxorub

1997
[Diffuse B-cell lymphoma associated with hemophagocytic syndrome].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1998, Volume: 39, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Drug Administration Schedule; Epir

1998
[A case of malignant lymphoma of the epididymis].
    Hinyokika kiyo. Acta urologica Japonica, 2000, Volume: 46, Issue:4

    Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Combined Modality

2000
Biotherapy for lymphoma.
    Current oncology reports, 2000, Volume: 2, Issue:2

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy

2000
Isolated primary non-Hodgkin's malignant lymphoma of the larynx.
    The Journal of laryngology and otology, 2001, Volume: 115, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Humans; Larynge

2001
[Ileal perforation due to cytomegalovirus enteritis under chemotherapy for malignant lymphoma. Report of a case].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2001, Volume: 98, Issue:10

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytomegalovirus Infections;

2001
[A primary malignant lymphoma of the appendix].
    Gan no rinsho. Japan journal of cancer clinics, 1990, Volume: 36, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Appendiceal Neoplasms; Combined Modality Therapy; Cy

1990

Trials

17 trials available for prednisolone and Lymphoma, B-Cell

ArticleYear
Rituximab plus high-dose chemotherapy (MegaCHOEP) or conventional chemotherapy (CHOEP-14) in young, high-risk patients with aggressive B-cell lymphoma: 10-year follow-up of a randomised, open-label, phase 3 trial.
    The Lancet. Haematology, 2021, Volume: 8, Issue:4

    Topics: Adult; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Central

2021
Rationale for optimal obinutuzumab/GA101 dosing regimen in B-cell non-Hodgkin lymphoma.
    Haematologica, 2016, Volume: 101, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antigens, CD20; Antineoplastic Ag

2016
Rationale for optimal obinutuzumab/GA101 dosing regimen in B-cell non-Hodgkin lymphoma.
    Haematologica, 2016, Volume: 101, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antigens, CD20; Antineoplastic Ag

2016
Rationale for optimal obinutuzumab/GA101 dosing regimen in B-cell non-Hodgkin lymphoma.
    Haematologica, 2016, Volume: 101, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antigens, CD20; Antineoplastic Ag

2016
Rationale for optimal obinutuzumab/GA101 dosing regimen in B-cell non-Hodgkin lymphoma.
    Haematologica, 2016, Volume: 101, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antigens, CD20; Antineoplastic Ag

2016
Dose-intensified treatment of Burkitt lymphoma and B-cell lymphoma unclassifiable, (with features intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma) in young adults (<50 years): a comparison of two adapted BFM protocols.
    American journal of hematology, 2010, Volume: 85, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Cohort Studies;

2010
Primary mediastinal B-cell lymphoma treated with CHOP-like chemotherapy with or without rituximab: results of the Mabthera International Trial Group study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2011, Volume: 22, Issue:3

    Topics: Adolescent; Adult; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Prot

2011
A phase II study of rituximab combined with pirarubicin-cyclophosphamide, vincristine and prednisolone regimen as first-line therapy for patients with indolent B-cell lymphoma.
    Leukemia & lymphoma, 2012, Volume: 53, Issue:2

    Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Cyclophospha

2012
Conventional chemotherapy (CHOEP-14) with rituximab or high-dose chemotherapy (MegaCHOEP) with rituximab for young, high-risk patients with aggressive B-cell lymphoma: an open-label, randomised, phase 3 trial (DSHNHL 2002-1).
    The Lancet. Oncology, 2012, Volume: 13, Issue:12

    Topics: Adolescent; Adult; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Prot

2012
Rituximab plus CHOP (R-CHOP) overcomes bcl-2--associated resistance to chemotherapy in elderly patients with diffuse large B-cell lymphoma (DLBCL).
    Blood, 2003, Jun-01, Volume: 101, Issue:11

    Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplas

2003
Practicability and acute haematological toxicity of 2- and 3-weekly CHOP and CHOEP chemotherapy for aggressive non-Hodgkin's lymphoma: results from the NHL-B trial of the German High-Grade Non-Hodgkin's Lymphoma Study Group (DSHNHL).
    Annals of oncology : official journal of the European Society for Medical Oncology, 2003, Volume: 14, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophospha

2003
Intestinal non-Hodgkin's lymphoma: a multicenter prospective clinical study from the German Study Group on Intestinal non-Hodgkin's Lymphoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Jul-15, Volume: 21, Issue:14

    Topics: Adult; Age Distribution; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Co

2003
Residual disease after chemotherapy in aggressive malignant lymphoma: the role of radiotherapy.
    Medical oncology (Northwood, London, England), 2005, Volume: 22, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Female;

2005
[Comparison between R-CHOP regimen and CHOP regimen in treating naive diffuse large B-cell lymphoma in China--a multi-center randomized trail].
    Ai zheng = Aizheng = Chinese journal of cancer, 2005, Volume: 24, Issue:12

    Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antigens, C

2005
Randomized phase II study of concurrent and sequential rituximab and CHOP chemotherapy in untreated indolent B-cell lymphoma.
    Cancer science, 2006, Volume: 97, Issue:4

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined

2006
Prospective clinical study of surgical resection followed by CHOP in localized intestinal diffuse large B cell lymphoma.
    Leukemia research, 2007, Volume: 31, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Th

2007
Mediastinal large B-cell lymphoma: clinical and immunohistological findings in 18 patients treated with different third-generation regimens.
    British journal of haematology, 1995, Volume: 89, Issue:4

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Cyta

1995
High-dose chemotherapy and autologous bone marrow transplantation compared with MACOP-B in aggressive B-cell lymphoma.
    The New England journal of medicine, 1997, May-01, Volume: 336, Issue:18

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Marrow Transplant

1997
Treatment and clinical management of primary mediastinal large B-cell lymphoma with sclerosis: MACOP-B regimen and mediastinal radiotherapy monitored by (67)Gallium scan in 50 patients.
    Blood, 1999, Nov-15, Volume: 94, Issue:10

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Citrates; Combined Modality Therap

1999
Peripheral T-cell lymphomas have a worse prognosis than B-cell lymphomas: a prospective study of 361 immunophenotyped patients treated with the LNH-84 regimen. The GELA (Groupe d'Etude des Lymphomes Agressives).
    Annals of oncology : official journal of the European Society for Medical Oncology, 1990, Volume: 1, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Humans; Im

1990

Other Studies

152 other studies available for prednisolone and Lymphoma, B-Cell

ArticleYear
Rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone (R-CHOP) therapy increases carotid intima-media thickness and plaque score with von Willebrand factor activity elevation in patients with malignant lymphoma.
    Journal of chemotherapy (Florence, Italy), 2022, Volume: 34, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Atherosclerosis; Carotid Intima-Media Thickness; Cyc

2022
Genetic polymorphisms and vincristine-induced peripheral neuropathy in patients treated with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone therapy.
    International journal of hematology, 2020, Volume: 111, Issue:5

    Topics: Antigens, Surface; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytochrome P-45

2020
Diffuse Large B-Cell Lymphoma Arising from the Lesion of Chronic Lobar Atelectasis.
    The Tohoku journal of experimental medicine, 2020, Volume: 250, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Female; Humans;

2020
Whole genome sequencing analysis of high confidence variants of B-cell lymphoma in Canis familiaris.
    PloS one, 2020, Volume: 15, Issue:8

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cyclophosphamide; Dog Di

2020
Prognostic significance of clinical presentation, induction and rescue treatment in 42 cases of canine centroblastic diffuse large B-cell multicentric lymphoma in the United Kingdom.
    Veterinary and comparative oncology, 2018, Volume: 16, Issue:2

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Anti

2018
Chemotherapy-induced exacerbations of thyroid orbitopathy in a patient with B-cell lymphoma.
    Orbit (Amsterdam, Netherlands), 2018, Volume: 37, Issue:4

    Topics: Administration, Oral; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy P

2018
B-cell follicular lymphoma presenting as facial papules.
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2018, Volume: 16, Issue:12

    Topics: Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Facial Dermatos

2018
Primary bone lymphoma: tunisian multicentric retrospective study about 32 cases.
    La Tunisie medicale, 2018, Volume: 96, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Neo

2018
Novel humanized anti-CD20 antibody BM-ca binds to a unique epitope and exerts stronger cellular activity than others.
    Cancer medicine, 2013, Volume: 2, Issue:2

    Topics: Animals; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Anti

2013
[Case of intravascular large B-cell lymphoma (IVLBCL) with central nervous system symptoms diagnosed by renal biopsy].
    Rinsho shinkeigaku = Clinical neurology, 2014, Volume: 54, Issue:6

    Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Biomarkers;

2014
Clinical features and treatment outcomes of primary cutaneous B-cell lymphoma: a single-center analysis in South Korea.
    International journal of hematology, 2015, Volume: 101, Issue:3

    Topics: Adult; Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols;

2015
Autologous peripheral blood stem cell mobilization following dose-adjusted cyclophosphamide, doxorubicin, vincristine, and prednisolone chemotherapy alone or in combination with rituximab in treating high-risk non-Hodgkin's lymphoma.
    Chinese journal of cancer, 2015, Sep-14, Volume: 34, Issue:11

    Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Cyclophospha

2015
[IMMUNOHISTOCHEMICAL FACTORS OF SMALL-CELL LYMPHOMAS AND CHOICE OF TREATMENT WTTH LEVEL INCLUSION].
    Likars'ka sprava, 2014, Issue:12

    Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Trans

2014
Reversible Atrial Fibrillation with Bradycardia Associated with Primary Cardiac B-Cell Lymphoma.
    Internal medicine (Tokyo, Japan), 2016, Volume: 55, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Atrial Fibrillation; Atrioventricular Block; Bradyca

2016
[Intravascular lymphomatosis manifesting clinically as subacute encephalopathy].
    Rinsho shinkeigaku = Clinical neurology, 2008, Volume: 48, Issue:5

    Topics: Acute Disease; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combin

2008
[HIV-related multiple non-Hodgkin lymphomas].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2008, Volume: 49, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Antiretroviral Therapy, Highly Active; Cyclophospham

2008
[Case of primary malignant lymphoma of the liver treated by R-CHOP therapy].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2009, Volume: 106, Issue:3

    Topics: Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Co

2009
[Intravascular lymphoma confirmed by brain biopsy, quickly treated by chemotherapy: a case report].
    No shinkei geka. Neurological surgery, 2009, Volume: 37, Issue:4

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy

2009
[Primary non-Hodgkin lymphoma of the sternum].
    Archivos de bronconeumologia, 2009, Volume: 45, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cyclophosphamide; Doxorubicin; Human

2009
Bilateral low-grade B-cell lymphoma of the breast: a case report with cytological, histological and immunohistochemical studies.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2009, Volume: 92, Issue:6

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Biopsy, Fine-Needle; Breast; C

2009
B-cell dominant lymphocytic primary angiitis of the central nervous system: four biopsy-proven cases.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2010, Volume: 30, Issue:2

    Topics: Adult; Antineoplastic Agents, Hormonal; B-Lymphocytes; Brain; Brain Neoplasms; Cyclophosphamide; Dia

2010
Gastric B-cell lymphoma with Mott cell differentiation in a dog.
    Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, 2009, Volume: 21, Issue:5

    Topics: Animals; Anti-Ulcer Agents; Cell Differentiation; Cimetidine; Dog Diseases; Dogs; Euthanasia; Gastro

2009
Resolution of massive pleural effusion due to lymphoma with intrapleural interleukin-2.
    American journal of hematology, 2010, Volume: 85, Issue:9

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy

2010
[Hepatitis B virus reactivation after cessation of prophylactic lamivudine therapy in B-cell lymphoma patients treated with rituximab combined CHOP therapy].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2009, Volume: 50, Issue:12

    Topics: Adult; Aged; Anti-HIV Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antine

2009
Telbivudine use in a patient affected by occult hepatitis B virus and B-cell non-Hodgkin lymphoma.
    Leukemia & lymphoma, 2010, Volume: 51, Issue:3

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy

2010
Solitary intradural extramedullary lymphoma of the cervical spine.
    Journal of neurosurgery. Spine, 2010, Volume: 12, Issue:4

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antimetabolites, Antineoplastic; Ant

2010
Two successive ocular malignancies in the same eye of a HIV-positive patient: a case report.
    Ocular immunology and inflammation, 2010, Volume: 18, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Blindness; Carcinoma, Squamous Cell; CD4 Lymp

2010
Chemotherapy-related polyneuropathy may deteriorate quality of life in patients with B-cell lymphoma.
    Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2010, Volume: 19, Issue:8

    Topics: Adult; Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols;

2010
A case of cutaneous B-cell lymphoma showing multiple lipoatrophy-like skin depressions.
    International journal of dermatology, 2010, Volume: 49, Issue:3

    Topics: Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Co

2010
Primary cutaneous Epstein-Barr virus-associated B-cell lymphoma arising at the site of subcutaneous injections of methotrexate.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Dec-01, Volume: 28, Issue:34

    Topics: Adrenal Cortex Hormones; Aged; Dermatologic Agents; Dermatomyositis; Epstein-Barr Virus Infections;

2010
Male gender is an adverse prognostic factor in B-cell lymphoma patients treated with immunochemotherapy.
    European journal of haematology, 2011, Volume: 86, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chem

2011
Primary diffuse large B-cell lymphoma of the lacrimal sac.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2010, Volume: 143, Issue:5 Suppl 3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Diagnos

2010
The incidence of Pneumocystis jirovecii pneumonia is not higher in patients receiving dose-dense therapy with rituximab, cyclophosphamide, non-pegylated liposomal doxorubicin, vincristine, and prednisolone and adequate Pneumocystis jirovecii pneumonia pro
    Leukemia & lymphoma, 2011, Volume: 52, Issue:1

    Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Antibiotic Prophylaxis; Antibodies, Monoclonal, Muri

2011
Bilateral retrobulbar neuritis in an adolescent boy with lymphoma.
    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2011, Volume: 15, Issue:1

    Topics: Administration, Oral; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide;

2011
CNS disease in younger patients with aggressive B-cell lymphoma: an analysis of patients treated on the Mabthera International Trial and trials of the German High-Grade Non-Hodgkin Lymphoma Study Group.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23, Issue:5

    Topics: Adolescent; Adult; Age of Onset; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Che

2012
Prolonged detection of herpes simplex virus type 2 (HSV-2) DNA in cerebrospinal fluid despite antiviral therapy in a patient with HSV-2-associated radiculitis.
    Antiviral therapy, 2012, Volume: 17, Issue:1

    Topics: Acyclovir; Aged; Antiviral Agents; DNA Copy Number Variations; DNA, Viral; Female; Herpes Simplex; H

2012
A case of B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma in a Korean child.
    Annals of laboratory medicine, 2012, Volume: 32, Issue:2

    Topics: Antineoplastic Agents; Bone Marrow Cells; Child, Preschool; Chromosomes, Human, Pair 14; Chromosomes

2012
Comparison on therapeutic effects of RFT and RCTVP regimen in the treatment of patients with indolent B-cell lymphoma in China.
    Medical oncology (Northwood, London, England), 2012, Volume: 29, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chem

2012
[Massive infiltration of the right vetricular wall caused by large B-cell lymphoma].
    Kardiologia polska, 2012, Volume: 70, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Echocardiography; Fat

2012
Lymphoma in an ileostomy.
    Postgraduate medical journal, 2002, Volume: 78, Issue:920

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Colitis, Ulcerative; Combined Modal

2002
[Diffuse large B-cell lymphoma mimicking Wegener's granulomatosis].
    Pneumonologia i alergologia polska, 2002, Volume: 70, Issue:3-4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Diagnosis, Differential; Do

2002
A significant diffuse component predicts for inferior survival in grade 3 follicular lymphoma, but cytologic subtypes do not predict survival.
    Blood, 2003, Mar-15, Volume: 101, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomyci

2003
High survival rate in childhood non-Hodgkin lymphoma without CNS involvement: results of BFM 95 study in Kuwait.
    Pediatric hematology and oncology, 2003, Volume: 20, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Burkitt Lymphoma; Child; Child, Presch

2003
[A case of primary hepatic lymphoma successfully treated by THP-COP therapy].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 2003, Volume: 40, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Drug Administra

2003
Concurrent mediastinal B cell lymphoma and chronic myeloid leukemia with an unusually favorable response to chemotherapy.
    Leukemia & lymphoma, 2003, Volume: 44, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Clone Cells; Combined Modal

2003
[Therapy-related acute myelogenous leukemia (AML-M6) with add(11) (q23) and del(20) (q11.2) developing via myelodysplastic syndrome after chemotherapy for malignant lymphoma].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2003, Volume: 44, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosomes, Human, Pair 11;

2003
Primary cardiac lymphoma diagnosed by transvenous biopsy under transesophageal echocardiographic guidance and treated with systemic chemotherapy.
    Echocardiography (Mount Kisco, N.Y.), 2003, Volume: 20, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cyclophosphamide; Doxorubicin; Echocardiogra

2003
[A case of primary malignant lymphoma of the duodenum successfully treated with dose escalating chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2003, Volume: 30, Issue:8

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Duodenal Neopla

2003
Favorable response to treatment of a child with T-cell-rich large B-cell lymphoma presenting with liver failure.
    Journal of pediatric hematology/oncology, 2003, Volume: 25, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Cyclophosphamide; Doxorubicin; Humans; Liver;

2003
Hemophagocytic syndrome in ileum-origin B-cell lymphoma.
    Journal of gastroenterology, 2003, Volume: 38, Issue:10

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols;

2003
Massive hyperplasia of marginal zone B-cells with clear cytoplasm in the lymph node: a case report.
    Pathology, research and practice, 2003, Volume: 199, Issue:9

    Topics: Anti-Bacterial Agents; Antigens, CD; Axilla; B-Lymphocytes; Biomarkers; Biopsy; Cytoplasm; Diagnosis

2003
Treatment of extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) with mitoxantrone, chlorambucil and prednisone (MCP).
    Annals of oncology : official journal of the European Society for Medical Oncology, 2003, Volume: 14, Issue:12

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Dis

2003
[Focal concentrations in the hepatic CT in superior vena cava thrombosis].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 2003, Volume: 175, Issue:12

    Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Antine

2003
[Primary malignant lymphoma arising from the nipple and areolar area of the breast].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2003, Volume: 44, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Fem

2003
[Testicular malignant lymphoma: a case report].
    Hinyokika kiyo. Acta urologica Japonica, 2003, Volume: 49, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Doxorub

2003
Successful treatment of diffuse large B-cell lymphoma following Waldenström's macroglobulinemia with CHOP chemotherapy followed by combination therapy of CHOP with rituximab.
    Internal medicine (Tokyo, Japan), 2004, Volume: 43, Issue:2

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Antineoplasti

2004
Malignant lymphoma associated with rheumatoid arthritis, developing shortly after initiation of oral methotrexate.
    Internal medicine (Tokyo, Japan), 2004, Volume: 43, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Antirheumatic Agents; Arthritis, Rheumatoid; Cycloph

2004
Intracellular IL-4/IFN-gamma producing peripheral T lymphocyte subsets in B cell non-Hodgkin's lymphoma patients.
    European journal of haematology, 2004, Volume: 72, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; CD4-Posit

2004
Primary mediastinal large B-cell lymphoma: a single-institution clinical study in Japan.
    International journal of hematology, 2004, Volume: 79, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclopho

2004
Tracheoesophageal fistula secondary to chemotherapy for malignant B-cell lymphoma of the thyroid: successful surgical treatment with jejunal interposition and mesenteric patch.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2004, Volume: 17, Issue:3

    Topics: Aged; Anastomosis, Surgical; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxor

2004
[Usefulness of FDG-PET in monitoring effects of the modality therapy for central nervous system malignant lymphoma: report of three cases].
    No shinkei geka. Neurological surgery, 2004, Volume: 32, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; Cyclopho

2004
[Treatment of primary mediastinal large B-cell lymphomas].
    Orvosi hetilap, 2004, Dec-12, Volume: 145, Issue:50

    Topics: Adult; Aged; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bleo

2004
[Case of central nervous system lymphoma metastasized to breast after remission by methotrexate chemotherapy].
    No shinkei geka. Neurological surgery, 2005, Volume: 33, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Cytarabine; Fatal

2005
CD20-negative pyothorax-associated B cell lymphoma.
    Acta haematologica, 2005, Volume: 113, Issue:2

    Topics: Aged; Aged, 80 and over; Antigens, CD20; Antineoplastic Combined Chemotherapy Protocols; Cyclophosph

2005
Intravascular lymphomatosis presenting with sudden hearing loss.
    Journal of the neurological sciences, 2005, May-15, Volume: 232, Issue:1-2

    Topics: Anti-Inflammatory Agents; Audiometry; Brain Neoplasms; Cerebellum; Corpus Callosum; Fatal Outcome; H

2005
[A case of pulmonary intravascular lymphoma treated with CHOP chemotherapy plus rituximab].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:4

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemot

2005
A 61-year-old man with dyspepsia and weight loss.
    PLoS medicine, 2005, Volume: 2, Issue:6

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy

2005
[Mediastinal large B-cell lymphoma with symptomatic superior vena cava syndrome in a patient with bichorial twin pregnancy in the 26th week of gestation: peri-and postpartal management -- a case report].
    Zentralblatt fur Gynakologie, 2005, Volume: 127, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cesarean Section; Cyclophosphamide; Doxorubic

2005
Primary cutaneous B-cell lymphoma.
    Journal of the American Academy of Dermatology, 2005, Volume: 53, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Borrelia burgdorferi

2005
Intravascular B-cell lymphoma diagnosed by skin biopsy.
    The Australasian journal of dermatology, 2005, Volume: 46, Issue:4

    Topics: Abdomen; Amyloidosis; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Diagnosis, D

2005
[A case of malignant lymphoma of the prostate].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 2005, Volume: 96, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; D

2005
Successful treatment of primary cardiac lymphoma with atrioventricular nodal block.
    International heart journal, 2005, Volume: 46, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Drug Administra

2005
[Non-Hodgkin malignant lymphoma of rib origin: report of a case].
    Kyobu geka. The Japanese journal of thoracic surgery, 2005, Volume: 58, Issue:13

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Combined Modality Therapy; Cyc

2005
Non-Hodgkin disease in beta-thalassemia major.
    American journal of hematology, 2006, Volume: 81, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; beta-Thalassemia; Child; Child, Preschool; Co

2006
[Long-term remission after CHOP therapy in a case of multifocal extranodal diffuse large B-cell lymphoma with t(1 ; 14) (p22 ; q32) and rearrangement of bcl-10].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2005, Volume: 46, Issue:10

    Topics: Adaptor Proteins, Signal Transducing; Aged; Antineoplastic Combined Chemotherapy Protocols; B-Cell C

2005
[A case of primary gastric malignant lymphoma perforated immediately after administration of chemotherapy].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2006, Volume: 103, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Humans; Lymphom

2006
[Effective combined modality therapy for a patient with primary adrenal lymphoma].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2006, Volume: 47, Issue:3

    Topics: Adrenal Gland Neoplasms; Adrenalectomy; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Deriv

2006
A malignant fibroleiomyoma of the testis.
    Clinical lymphoma & myeloma, 2006, Volume: 6, Issue:5

    Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Biopsy, Nee

2006
[The efficacy and adverse effects of rituximab with CHOP or THP-COP in old-old and extremely old patients with diffuse large B cell lymphoma].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 2006, Volume: 43, Issue:2

    Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplas

2006
Outcome for young high-risk aggressive B-cell lymphoma patients treated with CHOEP-14 and rituximab (R-CHOEP-14).
    Medical oncology (Northwood, London, England), 2006, Volume: 23, Issue:2

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antimetabolites, Antine

2006
[A case of primary pulmonary malignant lymphoma associated with autoimmune hemolytic anemia].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2006, Volume: 44, Issue:6

    Topics: Aged; Anemia, Hemolytic, Autoimmune; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived;

2006
'The sandwich sign' of mesenteric lymphoma.
    European journal of haematology, 2006, Volume: 77, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Female; Humans;

2006
Whole-brain radiotherapy and high-dose methylprednisolone for elderly patients with primary central nervous system lymphoma: Results of North Central Cancer Treatment Group (NCCTG) 96-73-51.
    International journal of radiation oncology, biology, physics, 2006, Aug-01, Volume: 65, Issue:5

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neop

2006
Whole-brain radiotherapy and high-dose methylprednisolone for elderly patients with primary central nervous system lymphoma: Results of North Central Cancer Treatment Group (NCCTG) 96-73-51.
    International journal of radiation oncology, biology, physics, 2006, Aug-01, Volume: 65, Issue:5

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neop

2006
Whole-brain radiotherapy and high-dose methylprednisolone for elderly patients with primary central nervous system lymphoma: Results of North Central Cancer Treatment Group (NCCTG) 96-73-51.
    International journal of radiation oncology, biology, physics, 2006, Aug-01, Volume: 65, Issue:5

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neop

2006
Whole-brain radiotherapy and high-dose methylprednisolone for elderly patients with primary central nervous system lymphoma: Results of North Central Cancer Treatment Group (NCCTG) 96-73-51.
    International journal of radiation oncology, biology, physics, 2006, Aug-01, Volume: 65, Issue:5

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neop

2006
[Non-Hodgkin's lymphoma of the parotid gland].
    Kulak burun bogaz ihtisas dergisi : KBB = Journal of ear, nose, and throat, 2006, Volume: 16, Issue:4

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Diagnosis, Differential; Dox

2006
Stroke as a consequence of delayed treatment of a primary B-cell thyroid lymphoma.
    Leukemia & lymphoma, 2006, Volume: 47, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Female; Humans; Lymph

2006
Disseminated intravascular B-cell lymphoma: clinicopathological features and outcome of three cases treated with anthracycline-based immunochemotherapy.
    The oncologist, 2006, Volume: 11, Issue:8

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy

2006
Lymphoma in a patient with systemic lupus erythematosus.
    Nature clinical practice. Rheumatology, 2006, Volume: 2, Issue:10

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Cyclophosphamide; Doxor

2006
18F-Fluorodeoxyglucose positron emission tomography for evaluation of intravascular large B-cell lymphoma.
    British journal of haematology, 2007, Volume: 136, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Female; Fluorod

2007
A case of polymyalgia rheumatica, microscopic polyangiitis, and B-cell lymphoma.
    Nature clinical practice. Rheumatology, 2006, Volume: 2, Issue:12

    Topics: Aged; Alendronate; Antibodies, Antineutrophil Cytoplasmic; Antineoplastic Combined Chemotherapy Prot

2006
[Concurrent chemo-radiotherapy for localized refractory non-Hodgkin's lymphoma--report of two cases].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; D

2007
Fatal fulminant Clostridium difficile colitis during CHOP therapy for lymphoma: an autopsy case.
    Internal medicine (Tokyo, Japan), 2007, Volume: 46, Issue:7

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Autopsy; Clostridioides difficile; Cyclophosph

2007
HLA-DR protein status predicts survival in patients with diffuse large B-cell lymphoma treated on the MACOP-B chemotherapy regimen.
    Leukemia & lymphoma, 2007, Volume: 48, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubici

2007
Successfully-treated mesenteric non-Hodgkin's lymphoma involving hepatic mass--a case report.
    Gan to kagaku ryoho. Cancer & chemotherapy, 2007, Volume: 34, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; D

2007
Absolute lymphocyte counts predicts response to chemotherapy and survival in diffuse large B-cell lymphoma.
    Leukemia, 2007, Volume: 21, Issue:10

    Topics: Antigens, CD20; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Human

2007
Primary cutaneous large B-cell lymphoma, leg type, presented with a migratory lesion.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2007, Volume: 21, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cyclophosphamide; Doxorubicin; Humans; Leg;

2007
[Primary diffuse large B-cell lymphoma of the bone marrow complicated with autoimmune hemolytic anemia and erythroid hypoplasia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2007, Volume: 48, Issue:7

    Topics: Aged; Anemia, Hemolytic, Autoimmune; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived;

2007
Diffuse large B-cell lymphoma mimicking advanced basal cell carcinoma.
    Journal of the National Medical Association, 2007, Volume: 99, Issue:8

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy

2007
Aggressive B-cell lymphoma with dual surface immunoglobulin light-chain expression.
    Internal medicine (Tokyo, Japan), 2007, Volume: 46, Issue:17

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemot

2007
Primary testicular precursor B-lymphoblastic lymphoma: a rare entity.
    Leukemia & lymphoma, 2007, Volume: 48, Issue:10

    Topics: Adult; Age Factors; Antigens, CD20; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide

2007
[Case of malignant lymphoma associated with rheumatoid arthritis].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2008, Volume: 46, Issue:2

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemot

2008
[Non-Hodgkin's lymphoma of the bone, with reference to MRI findings following treatment].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Cisplatin; Cycloph

1993
[Lymphomas of the skin].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chemotherapy, Adjuvant; Combined Modality

1993
Synchronous primary hepatic lymphoma and epidermoid lung carcinoma treated with chemotherapy and surgery.
    American journal of clinical oncology, 1995, Volume: 18, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Combined Modality Therapy;

1995
Complete regression of recurrent diffuse malignant lymphoma after withdrawal of cyclosporin A in a renal transplant recipient.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1994, Volume: 9, Issue:8

    Topics: Azathioprine; Cyclosporine; Drug Therapy, Combination; Female; Humans; Immunosuppression Therapy; Ki

1994
[Bilateral kidney enlargement with kidney failure. Manifestation of primary extranodal B-cell lymphoma after long-term immunosuppression].
    Medizinische Klinik (Munich, Germany : 1983), 1994, Feb-15, Volume: 89, Issue:2

    Topics: Azathioprine; Female; Humans; Hypertrophy; Kidney; Kidney Failure, Chronic; Kidney Neoplasms; Lupus

1994
[Parapsoriasis en plaque suspected of progression to mycosis fungoides associated with extranodal malignant B cell lymphoma of the cheek].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1993, Volume: 34, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cheek; Cyclophosphamide; Doxorubicin; Facial Neoplas

1993
Posttransplantation lymphoproliferative disorders treated with cyclophosphamide-doxorubicin-vincristine-prednisone chemotherapy.
    Cancer, 1993, Nov-01, Volume: 72, Issue:9

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Humans; Immuno

1993
Ocular lymphoma in a patient with chronic lymphocytic leukemia.
    American journal of ophthalmology, 1996, Volume: 122, Issue:2

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Biopsy; Combined Modality Therapy; Eye Neo

1996
Non-Hodgkin's lymphoma of the thyroid. A clinical study of twenty-two cases.
    Acta oncologica (Stockholm, Sweden), 1996, Volume: 35, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Anti

1996
[Autopsy case of angiotropic lymphoma complicated with interstitial pneumonia during VEPA therapy and monocytosis in the early stage].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1996, Feb-10, Volume: 85, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Capillaries; Cyclophosphamide; Doxorubicin; He

1996
Successful chemotherapy including epirubicin in a pregnant non-Hodgkin's lymphoma patient.
    Leukemia & lymphoma, 1995, Volume: 20, Issue:1-2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Epirubicin; Female; Follow-Up Studies; Humans

1995
[Long-term survivor (15 years) following central nervous system involvement in B-cell lymphoma].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1996, Volume: 37, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cyclophosphamide;

1996
Immunologic disorders in posttransplant lymphoma: therapeutic implications.
    Transplantation proceedings, 1996, Volume: 28, Issue:6

    Topics: Adult; Antigens, CD; Azathioprine; B-Lymphocytes; Cyclosporine; Herpesviridae Infections; Herpesviru

1996
Bilateral adrenal lymphoma with neoplastic angioendotheliosis.
    Internal medicine (Tokyo, Japan), 1997, Volume: 36, Issue:1

    Topics: Acute Kidney Injury; Addison Disease; Adrenal Gland Neoplasms; Antineoplastic Combined Chemotherapy

1997
[Combination chemotherapy with BH-AC, mitoxantrone, etoposide, and prednisolone to refractory or relapsed malignant lymphoma].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Administration Schedul

1997
[A case of malignant lymphoma after renal transplantation].
    No shinkei geka. Neurological surgery, 1997, Volume: 25, Issue:7

    Topics: Adult; Azathioprine; Brain Neoplasms; Herpesviridae Infections; Herpesvirus 4, Human; Humans; Immuno

1997
Granuloma annulare in a patient with malignant lymphoma.
    Dermatology (Basel, Switzerland), 1997, Volume: 195, Issue:1

    Topics: Aged; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormona

1997
[Autologous peripheral blood stem cell transplantation for CHOP-resistant mediastinal diffuse large B-cell lymphoma].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1997, Volume: 38, Issue:8

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Dr

1997
Non-Hodgkin's ovarian lymphoma during adolescence: report of two cases.
    Journal of pediatric and adolescent gynecology, 1997, Volume: 10, Issue:4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Burkitt Lymphoma; Combined Mo

1997
Two cases of fatal bleomycin pneumonitis complicating the treatment of non-Hodgkin's lymphoma.
    Clinical and laboratory haematology, 1998, Volume: 20, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclophosphamide; Doxorubicin; Etop

1998
[A case of primary malignant lymphoma of the bladder].
    Hinyokika kiyo. Acta urologica Japonica, 1998, Volume: 44, Issue:8

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Drug Administr

1998
[Acute mitral regurgitation caused by malignant lymphoma of the posterior mediastinum].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1998, Volume: 39, Issue:8

    Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclophospha

1998
Systemic polychemotherapy in the treatment of primary cutaneous lymphomas: a clinical follow-up study of 81 patients treated with COP or CHOP.
    Leukemia & lymphoma, 1998, Volume: 31, Issue:5-6

    Topics: Adult; Aged; Aged, 80 and over; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Bone Marro

1998
[A case of non-Hodgkin's lymphoma presenting with acute renal failure diagnosed by renal biopsy].
    Nihon Jinzo Gakkai shi, 1999, Volume: 41, Issue:5

    Topics: Acute Kidney Injury; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cyclophosphamide; Doxor

1999
[A case of malignant lymphoma of the testis: characterization with ultrasonography and magnetic resonance imaging].
    Hinyokika kiyo. Acta urologica Japonica, 1999, Volume: 45, Issue:9

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; D

1999
[A case of primary malignant lymphoma of the bladder].
    Hinyokika kiyo. Acta urologica Japonica, 1999, Volume: 45, Issue:10

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Drug Administration S

1999
Paraneoplastic pemphigus in two patients with B-cell non-Hodgkin's lymphoma: significant responses to cyclophosphamide and prednisolone.
    American journal of hematology, 2000, Volume: 63, Issue:2

    Topics: Aged; Anti-Inflammatory Agents; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Fa

2000
[Two cases of intravascular lymphomatosis diagnosed antemortem by transbronchial lung biopsy].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2000, Volume: 38, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cyclophosphamide; Doxorubicin; Humans;

2000
[A case of massive chylothorax during the course of malignant lymphoma].
    Polskie Archiwum Medycyny Wewnetrznej, 1999, Volume: 101, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chylothorax; Cyclophosphamide; Doxorubicin; Dr

1999
[Perineural spreading along the trigeminal nerve in a patient with primary intracranial malignant lymphoma: a case report].
    No shinkei geka. Neurological surgery, 2000, Volume: 28, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cavernous Sinus; Cranial Nerve Neop

2000
Secondary cutaneous infiltration in B cell chronic lymphocytic leukemia.
    Acta haematologica, 2000, Volume: 103, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamide; Doxorubicin; Histidi

2000
Elevated serum CA-125 concentrations due to expression by a diffuse large B-cell lymphoma.
    Annals of clinical biochemistry, 2000, Volume: 37 ( Pt 4)

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; CA-125 Antigen; Cyclophosphamide;

2000
Primary effusion lymphoma with B-cell phenotype.
    American journal of hematology, 2000, Volume: 64, Issue:4

    Topics: Aged; Antigens, CD; Antineoplastic Agents, Hormonal; Female; Gene Rearrangement; Genes, Immunoglobul

2000
[Lymphoma of the knee joint simulating patellar fracture].
    Harefuah, 1999, Jan-15, Volume: 136, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; D

1999
[Beneficial effects of CHOP therapy in a case of intravascular large B-cell lymphoma diagnosed by skin biopsy].
    Rinsho shinkeigaku = Clinical neurology, 2000, Volume: 40, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cyclophosphamide; Doxorubicin; Humans; Lymph

2000
Complete cure of malignant lymphoma of the stomach with a huge adrenal lesion achieved by preoperative chemotherapy and surgery: report of a case.
    Surgery today, 2001, Volume: 31, Issue:1

    Topics: Adrenal Gland Neoplasms; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy;

2001
[CHF arising after low dose THP-COP chemotherapy in an elderly patient with malignant lymphoma].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 2001, Volume: 38, Issue:4

    Topics: Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide;

2001
[Testicular malignant lymphoma: report of two cases].
    Hinyokika kiyo. Acta urologica Japonica, 2001, Volume: 47, Issue:8

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Cyclophosphamide; Doxo

2001
T-cell-rich B-cell lymphoma. Analysis of clinical features, response to treatment, survival and comparison with diffuse large B-cell lymphoma.
    Oncology, 2001, Volume: 61, Issue:4

    Topics: Aged; Antigens, CD; Antigens, CD20; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide

2001
A prolonged APTT in a patient with a low grade malignant NHL - a case report.
    Haematologica, 2002, Volume: 87, Issue:2

    Topics: Anemia; Antineoplastic Combined Chemotherapy Protocols; Autoantibodies; Blood Coagulation Factors; C

2002
[Plasma exchange and continuous hemodiafiltration as an initial treatment for diffuse large B-cell lymphoma-associated hemophagocytic syndrome].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2002, Volume: 43, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Hemodiafiltrati

2002
Intestinal lymphoma perforations as a consequence of highly effective anti-CD20 antibody therapy.
    Transplantation, 2002, Feb-27, Volume: 73, Issue:4

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antigens, CD20; Antineoplastic

2002
Urticarial vasculitis: a paraneoplastic presentation of B-cell non-Hodgkin's lymphoma.
    Rheumatology (Oxford, England), 2002, Volume: 41, Issue:4

    Topics: Drug Therapy, Combination; Female; Humans; Lymphoma, B-Cell; Methotrexate; Middle Aged; Paraneoplast

2002
[A case of malignant lymphoma of the stomach in which preoperative chemotherapy provided a complete response].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2002, Volume: 29, Issue:6

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Doxorubicin; Female; Gastrec

2002
Parathyroid hormone-related protein as a cause of hypercalcemia in a B-cell type malignant lymphoma.
    Internal medicine (Tokyo, Japan), 1992, Volume: 31, Issue:8

    Topics: Aclarubicin; Adult; Alkaline Phosphatase; Antineoplastic Combined Chemotherapy Protocols; Calcitriol

1992
[A case of mediastinal malignant lymphoma with cardiac tamponade treated effectively with chemotherapy].
    Nihon Kyobu Shikkan Gakkai zasshi, 1992, Volume: 30, Issue:7

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cardiac Tamponade; Cyclophosphamide; Doxorubic

1992
Bilateral primary non-Hodgkin's lymphoma of the adrenal glands with adrenal insufficiency: a case report.
    Hinyokika kiyo. Acta urologica Japonica, 1992, Volume: 38, Issue:3

    Topics: Adrenal Gland Neoplasms; Adrenal Insufficiency; Aged; Antineoplastic Combined Chemotherapy Protocols

1992
NonEBV-related B-cell lymphoma in a renal transplant patient responding to acyclovir and reduction in immunosuppression.
    Postgraduate medical journal, 1992, Volume: 68, Issue:796

    Topics: Acyclovir; Azathioprine; Cyclosporine; Drug Therapy, Combination; Female; Humans; Immunocompromised

1992
Treatment for B-cell-type lymphoma in a girl associated with Bloom's syndrome.
    Clinical genetics, 1992, Volume: 41, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bloom Syndrome; Child; Chromosome Aberrations; Cyclo

1992
Similar outcome of treatment of B-cell and T-cell diffuse large-cell lymphomas: the Stanford experience.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1991, Volume: 9, Issue:8

    Topics: Actuarial Analysis; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cyclopho

1991
Malignant lymphoma of the testis presenting as primary testicular tumor.
    Hinyokika kiyo. Acta urologica Japonica, 1991, Volume: 37, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Doxorub

1991
Angiotropic B-cell lymphoma (malignant angioendotheliomatosis): failure of systemic chemotherapy.
    The British journal of dermatology, 1990, Volume: 123, Issue:6

    Topics: Aged; Allopurinol; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamide; F

1990