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prednisolone and Lymphocytopenia

prednisolone has been researched along with Lymphocytopenia in 32 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Research Excerpts

ExcerptRelevanceReference
"From a controlled prednisolone therapy trial 130 patients with chronic pulmonary sarcoidosis who had already finished their drug-therapy were evaluated."7.65[Prognostic evaluation of the absolute lymphopenia during prednisolone therapy of chronic pulmonary sarcoidosis (author's transl)]. ( Böttger, D, 1976)
" The pharmacodynamic component of the model was a hyperbolic function in which a threshold concentration parameter had to be incorporated."5.27Pharmacokinetic-pharmacodynamic modeling of prednisolone-induced lymphocytopenia in man. ( Endert, E; Oosterhuis, B; Sauerwein, HP; Schellekens, PT; ten Berge, RJ; van Boxtel, CJ, 1984)
"A patient with long-standing filarial chyluria developed severe lymphocytopenia, extensive mucosal candidiasis and disseminated cryptococcosis when given small doses of prednisolone and azathioprine, for the treatment of a co-existing chronic active hepatitis."3.66Filarial chyluria with opportunistic infections. ( Chandy, M; Date, A; Pulimood, BM, 1983)
"From a controlled prednisolone therapy trial 130 patients with chronic pulmonary sarcoidosis who had already finished their drug-therapy were evaluated."3.65[Prognostic evaluation of the absolute lymphopenia during prednisolone therapy of chronic pulmonary sarcoidosis (author's transl)]. ( Böttger, D, 1976)
"Neutropenia is a prominent feature in cases of human T-cell LGLL but is normally absent in canine CLL."1.51Chronic lymphopenia and neutropenia in a dog with large granular lymphocytic leukemia. ( Museux, K; Rodriguez Piñeiro, I; Rosenberg, D; Turinelli, V, 2019)
"Hong Kong has been severely affected by severe acute respiratory syndrome (SARS)."1.32Clinical presentations and outcome of severe acute respiratory syndrome in children. ( Chan, PK; Cheng, WT; Chiu, MC; Chu, WC; Fok, TF; Fong, NC; Hon, KL; Kwan, YW; Leung, CW; Li, AM; Li, CK; Ng, PC; Tam, JS, 2003)
" The pharmacodynamic component of the model was a hyperbolic function in which a threshold concentration parameter had to be incorporated."1.27Pharmacokinetic-pharmacodynamic modeling of prednisolone-induced lymphocytopenia in man. ( Endert, E; Oosterhuis, B; Sauerwein, HP; Schellekens, PT; ten Berge, RJ; van Boxtel, CJ, 1984)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199019 (59.38)18.7374
1990's4 (12.50)18.2507
2000's4 (12.50)29.6817
2010's4 (12.50)24.3611
2020's1 (3.13)2.80

Authors

AuthorsStudies
Museux, K1
Turinelli, V1
Rosenberg, D1
Rodriguez Piñeiro, I1
Querido, S1
Calça, R1
Weigert, A1
Francisco, D1
Adragão, T1
Ana Pessanha, M1
Gomes, P1
Rodrigues, L1
Figueira, JM1
Cardoso, C1
Machado, D1
Mracsko, E1
Liesz, A1
Karcher, S1
Zorn, M1
Bari, F1
Veltkamp, R1
Bai, YX1
Chu, JG1
Xiao, T1
Chen, HD1
Böttcher, A1
Guder, E1
Just, T1
Song, J1
Park, YB1
Suh, CH1
Lee, SK1
Hon, KL1
Leung, CW1
Cheng, WT1
Chan, PK1
Chu, WC1
Kwan, YW1
Li, AM1
Fong, NC1
Ng, PC1
Chiu, MC1
Li, CK1
Tam, JS1
Fok, TF1
Panesar, NS1
VERGA, L1
Jetzek-Zader, M1
Gudowius, S1
Feyen, O1
Stevens, M1
Lipfert, P1
Niehues, T1
Veys, EM1
Hermanns, P1
Verbruggen, G1
Mielants, H1
Date, A1
Chandy, M1
Pulimood, BM1
Bast, RC1
Reinherz, EL1
Maver, C1
Lavin, P1
Schlossman, SF1
ten Berge, RJ2
Sauerwein, HP2
Yong, SL1
Schellekens, PT4
Oosterhuis, B1
Endert, E1
van Boxtel, CJ2
Tanizaki, Y1
Kitani, H1
Mifune, T1
Mitsunobu, F1
Kajimoto, K1
Sugimoto, K1
Tokano, Y1
Miyake, S1
Kayagaki, N1
Nozawa, K1
Morimoto, S1
Azuma, M1
Yagita, H1
Takasaki, Y1
Okumura, K1
Hashimoto, H1
Shilov, EM1
Tareeva, IE1
Gordovskaia, NB1
Liburdy, RP1
Scheel, J1
Duswald, KH1
Ring, J2
Seifert, J2
Scholz, S1
Brendel, W2
Tanner, AR1
Powell, LW1
Böttger, D2
Fauci, AS1
Bloemena, E2
Weinreich, S2
Koopmans, RP1
Mansurov, KhKh1
Asfandiiarova, NS1
Nikolaeva, OS1
Mansurova, FKh1
Rasunova, TKh1
Lob, G1
Coulin, K1
Angstwurm, H1
Frick, E1
Brass, B1
Mertin, J1
Backmund, H1
McCrory, WW1
Shibuya, M1
Lu, WH1
Lewy, JE1
Glen, AC1
Bell, PR1
Briggs, JD1
Paton, AM1
Calman, KC1
Linton, AL1
Mikami, R1
Nomura, Y1
Takao, M1
Hongo, O1
Mizoguchi, A1
Arndt, HJ1

Reviews

1 review available for prednisolone and Lymphocytopenia

ArticleYear
Corticosteroids in liver disease: possible mechanisms of action, pharmacology, and rational use.
    Gut, 1979, Volume: 20, Issue:12

    Topics: Adrenal Cortex Hormones; Chronic Disease; Hepatitis; Humans; Immunity, Cellular; Liver Diseases; Liv

1979

Trials

3 trials available for prednisolone and Lymphocytopenia

ArticleYear
A single intravenous dose of prednisolone induces phosphatidylserine externalization, loss of surface marker expression and a 24-h net increase in human peripheral blood lymphocytes ex vivo.
    Rheumatology international, 2007, Volume: 27, Issue:7

    Topics: Adult; Antigens, Surface; Apoptosis; B-Lymphocytes; Cross-Over Studies; Flow Cytometry; Glucocortico

2007
Intensive immunosuppression in the treatment of multiple sclerosis.
    Lancet (London, England), 1974, Nov-09, Volume: 2, Issue:7889

    Topics: Adult; Animals; Antilymphocyte Serum; Azathioprine; Cells, Cultured; Drainage; Drug Therapy, Combina

1974
Therapeutic and toxic effects observed with different dosage programs of cyclophosphamide in treatment of steroid-responsive but frequently relapsing nephrotic syndrome.
    The Journal of pediatrics, 1973, Volume: 82, Issue:4

    Topics: Adolescent; Alopecia; Child; Child, Preschool; Cyclophosphamide; Digestive System; Dose-Response Rel

1973

Other Studies

28 other studies available for prednisolone and Lymphocytopenia

ArticleYear
Chronic lymphopenia and neutropenia in a dog with large granular lymphocytic leukemia.
    Veterinary clinical pathology, 2019, Volume: 48, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Asparaginase; Chronic Disease; Dogs; Leukemia, Large Granular Lympho

2019
Kinetics of torquetenovirus DNA load in a recent kidney transplant recipient with mild SARS-CoV-2 infection and a failed antibody response.
    Transplant infectious disease : an official journal of the Transplantation Society, 2021, Volume: 23, Issue:2

    Topics: Adult; Antibodies, Viral; Comorbidity; COVID-19; COVID-19 Nucleic Acid Testing; COVID-19 Serological

2021
Differential effects of sympathetic nervous system and hypothalamic-pituitary-adrenal axis on systemic immune cells after severe experimental stroke.
    Brain, behavior, and immunity, 2014, Volume: 41

    Topics: Animals; Apoptosis; Cells, Cultured; Corticosterone; Cortisone; Epinephrine; Feedback, Physiological

2014
Pemphigus vulgaris-associated interstitial lung disease.
    Dermatologic therapy, 2016, Volume: 29, Issue:4

    Topics: Female; Humans; Lung Diseases, Interstitial; Lymphopenia; Middle Aged; Pemphigus; Prednisolone

2016
[Unilateral odynophagia in rheumatoid arthritis].
    Laryngo- rhino- otologie, 2011, Volume: 90, Issue:8

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cooperative Behavior; Deglutition Disorders; Diagnosis,

2011
Transient panhypogammaglobulinaemia and B-lymphocyte deficiency in a patient with neuropsychiatric systemic lupus erythematosus after immunosuppressive therapy.
    Clinical rheumatology, 2003, Volume: 22, Issue:1

    Topics: Adult; Agammaglobulinemia; B-Lymphocytes; Female; Humans; Immunosuppressive Agents; Lupus Vasculitis

2003
Clinical presentations and outcome of severe acute respiratory syndrome in children.
    Lancet (London, England), 2003, May-17, Volume: 361, Issue:9370

    Topics: Administration, Oral; Adolescent; Adult; Age Factors; Cefotaxime; Child; Child, Preschool; Clarithro

2003
Lymphopenia in SARS.
    Lancet (London, England), 2003, Jun-07, Volume: 361, Issue:9373

    Topics: Adrenocorticotropic Hormone; Glucocorticoids; Humans; Hydrocortisone; Lymphopenia; Prednisolone; Sev

2003
[Karyometric and cytochemical aspects of lymphopenia induced by 6alpha-methylprednisolone].
    Il Farmaco; edizione scientifica, 1960, Volume: 15

    Topics: Humans; Leukopenia; Lymphocytes; Lymphopenia; Methylprednisolone; Prednisolone

1960
Immunoregulatory changes in autoimmune disease.
    Diagnostic immunology, 1983, Volume: 1, Issue:3

    Topics: Adult; Aged; Arthritis, Rheumatoid; Autoimmune Diseases; Female; Humans; Immunosuppressive Agents; L

1983
Filarial chyluria with opportunistic infections.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1983, Volume: 77, Issue:1

    Topics: Azathioprine; Candidiasis; Chyle; Cryptococcosis; Filariasis; Hepatitis, Chronic; Humans; Lymphopeni

1983
Contrasting effects of cyclophosphamide and prednisolone on the phenotype of human peripheral blood leukocytes.
    Clinical immunology and immunopathology, 1983, Volume: 28, Issue:1

    Topics: Adult; Antigens, Differentiation, T-Lymphocyte; Antigens, Surface; B-Lymphocytes; Cyclophosphamide;

1983
Administration of prednisolone in vivo affects the ratio of OKT4/OKT8 and the LDH-isoenzyme pattern of human T lymphocytes.
    Clinical immunology and immunopathology, 1984, Volume: 30, Issue:1

    Topics: Adult; Antibodies, Monoclonal; B-Lymphocytes; Humans; Isoenzymes; L-Lactate Dehydrogenase; Leukocyte

1984
Pharmacokinetic-pharmacodynamic modeling of prednisolone-induced lymphocytopenia in man.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 229, Issue:2

    Topics: Adult; Dose-Response Relationship, Drug; Humans; Hydrocortisone; Kinetics; Lymphopenia; Middle Aged;

1984
Effects of glucocorticoids on humoral and cellular immunity and on airway inflammation in patients with steroid-dependent intractable asthma.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 1993, Volume: 30, Issue:6

    Topics: Adult; Aged; Antibody Formation; Asthma; Beclomethasone; Bronchoalveolar Lavage Fluid; Female; Human

1993
Soluble Fas molecule in the serum of patients with systemic lupus erythematosus.
    Journal of clinical immunology, 1996, Volume: 16, Issue:5

    Topics: CD4 Antigens; CD8 Antigens; Enzyme-Linked Immunosorbent Assay; fas Receptor; Humans; Lupus Erythemat

1996
[Effect of prednisolone and azathioprine on T- and B-lymphocyte number in peripheral blood of patients with glomerulonephritis and systemic lupus erythematosus].
    Terapevticheskii arkhiv, 1978, Volume: 50, Issue:6

    Topics: Adolescent; Adult; Azathioprine; B-Lymphocytes; Glomerulonephritis; Humans; Leukocyte Count; Lupus E

1978
Radiofrequency radiation alters the immune system: modulation of T- and B-lymphocyte levels and cell-mediated immunocompetence by hyperthermic radiation.
    Radiation research, 1979, Volume: 77, Issue:1

    Topics: Adrenal Cortex Hormones; Animals; B-Lymphocytes; Fever; Hypersensitivity, Delayed; Immunity, Cellula

1979
[Long-term therapy using horse anti-dog lymphocyte globulin without sensitization against horse protein].
    Blut, 1977, Volume: 34, Issue:4

    Topics: Animals; Antilymphocyte Serum; Carnivora; Dogs; Drug Hypersensitivity; Female; Horses; Immunoglobuli

1977
Prognostic significance of lymphopenia in pulmonary sarcoidosis.
    Zeitschrift fur Erkrankungen der Atmungsorgane, 1977, Volume: 149, Issue:2

    Topics: Humans; Lung Diseases; Lymphopenia; Prednisolone; Prognosis; Recurrence; Sarcoidosis

1977
Corticosteroids and circulating lymphocytes.
    Transplantation proceedings, 1975, Volume: 7, Issue:1

    Topics: Administration, Oral; Animals; Cell Movement; Chromium Radioisotopes; Glucocorticoids; Guinea Pigs;

1975
[Prognostic evaluation of the absolute lymphopenia during prednisolone therapy of chronic pulmonary sarcoidosis (author's transl)].
    Zeitschrift fur Erkrankungen der Atmungsorgane, 1976, Volume: 144, Issue:1

    Topics: Chronic Disease; Humans; Lung Diseases; Lymphopenia; Prednisolone; Prognosis; Recurrence; Sarcoidosi

1976
The influence of prednisolone on the recirculation of peripheral blood lymphocytes in vivo.
    Clinical and experimental immunology, 1990, Volume: 80, Issue:3

    Topics: Animals; Cell Movement; Fluorescein-5-isothiocyanate; Fluoresceins; Kinetics; Lymphocytes; Lymphopen

1990
Pharmacodynamic modeling of lymphocytopenia and whole blood lymphocyte cultures in prednisolone-treated individuals.
    Clinical immunology and immunopathology, 1990, Volume: 57, Issue:3

    Topics: Administration, Oral; Adult; Antibodies, Monoclonal; Antilymphocyte Serum; Cell Division; Humans; Im

1990
[Immunocorrective therapy of patients with chronic active liver diseases of a viral nature].
    Terapevticheskii arkhiv, 1987, Volume: 59, Issue:2

    Topics: Adjuvants, Immunologic; Adolescent; Adult; Azathioprine; Female; Hepatitis B; Hepatitis, Chronic; Hu

1987
Lymphocyte monitoring by blood lymphocyte counts and RNA-DNA determination in patients with a renal allograft.
    Transplantation, 1971, Volume: 12, Issue:6

    Topics: Adult; Azathioprine; DNA; Female; Graft Rejection; Humans; Immunosuppression Therapy; Kidney Transpl

1971
[Pulmonary sarcoidosis--with special reference to the case presenting rebound phenomena in the course of steroid therapy together with superficial lymph node swelling, tonsillopathy and lymphopenia].
    Naika. Internal medicine, 1971, Volume: 27, Issue:6

    Topics: Adult; Biopsy; Female; Humans; Lung Diseases; Lymph Nodes; Lymphatic Diseases; Lymphopenia; Palatine

1971
[Fulminating epiglottitis in children. Report on 50 cases].
    Deutsche medizinische Wochenschrift (1946), 1971, Apr-02, Volume: 96, Issue:14

    Topics: Acute Disease; Adolescent; Child; Child, Preschool; Chloramphenicol; Epiglottis; Female; Fever; Germ

1971