Page last updated: 2024-11-06

prednisolone and Low Back Pain

prednisolone has been researched along with Low Back Pain in 32 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Low Back Pain: Acute or chronic pain in the lumbar or sacral regions, which may be associated with musculo-ligamentous SPRAINS AND STRAINS; INTERVERTEBRAL DISK DISPLACEMENT; and other conditions.

Research Excerpts

ExcerptRelevanceReference
"A retrospective study of medical records of 67 patients (68 injected discs) given an intradiscal injection of acetate of prednisolone for low back pain with endplate signal changes on magnetic resonance imaging and/or evidence of fast destructive discopathy, as well as records of 85 patients (55 women, mean age 49 +/-9 years) to assess the effectiveness of intradiscal injection: the global appreciation of the patient (excellent, good, mild, none, worse) concerning the result of the intradiscal injection at one, three and six months."9.11[Intradiscal injection of acetate of prednisolone in severe low back pain: complications and patients' assessment of effectiveness]. ( Benyahya, R; Demaille-Wlodyka, S; Fayad, F; Lefevre-Colau, MM; Mayoux-Benhamou, MA; Poiraudeau, S; Rannou, F; Revel, M, 2004)
"A retrospective study of medical records of 67 patients (68 injected discs) given an intradiscal injection of acetate of prednisolone for low back pain with endplate signal changes on magnetic resonance imaging and/or evidence of fast destructive discopathy, as well as records of 85 patients (55 women, mean age 49 +/-9 years) to assess the effectiveness of intradiscal injection: the global appreciation of the patient (excellent, good, mild, none, worse) concerning the result of the intradiscal injection at one, three and six months."5.11[Intradiscal injection of acetate of prednisolone in severe low back pain: complications and patients' assessment of effectiveness]. ( Benyahya, R; Demaille-Wlodyka, S; Fayad, F; Lefevre-Colau, MM; Mayoux-Benhamou, MA; Poiraudeau, S; Rannou, F; Revel, M, 2004)
" During a second infiltration of prednisolone acetate, the patient reported feeling a heat sensation in his legs and concomitantly developed facial flushing."4.86A rare case of paraplegia complicating a lumbar epidural infiltration. ( Berets, O; Defuentes, G; Dubecq, C; Escobar, E; Lapeyre, E; Rogez, D; Soula, M; Thefenne, L; Zing, E, 2010)
" Upon histologic examination, the tumor was determined to be parathyroidal chief-cell hyperplasia and the patient was treated with melphalan and prednisolone."4.79A case of primary hyperparathyroidism accompanying multiple myeloma. ( Hayakawa, N; Kageyama, J; Kashihara, N; Kataoka, H; Kawashima, M; Makino, H; Mimura, Y; Ogura, T; Otsuka, F; Yamauchi, T, 1997)
"Prednisolone was assayed in all samples using high performance liquid chromatography and its binding to plasma proteins was determined using ultrafiltration."2.68Prednisolone concentrations in cerebrospinal fluid after oral prednisone. Preliminary data. ( Bannwarth, B; D'Yvoire, MB; Dehais, J; Péhourcq, F; Schaeverbeke, T; Vernhes, JP, 1997)
"Infiltration procedures are a common treatment of lumbar radiculopathy."1.42CT-guided infiltration saves surgical intervention and fastens return to work compared to anatomical landmark-guided infiltration in patients with lumbosciatica. ( Buhr, M; Deml, MC; Kabir, K; Pflugmacher, R; Riedel, R; Rommelspacher, Y; Wimmer, MD, 2015)
"Membranous nephropathy is uncommon in Chinese children and could be a possible early presentation of SLE."1.36An unusual case of loin pain and nephritis. ( Chiu, MC; Lai, WM; Ma, AL, 2010)
" Adverse events occurring immediately after the procedure and within the first month were collected."1.36Feasibility and safety of ultrasound-guided caudal epidural glucocorticoid injections. ( Berthelot, JM; Blanchais, A; Glemarec, J; Guillot, P; Le Goff, B; Maugars, Y, 2010)
"Limbic encephalitis is typically characterised by a sub-acute onset of disorientation, amnesia and seizures, but the clinical spectrum is not yet fully defined and the syndrome could be under-diagnosed."1.35Hypothermia in VGKC antibody-associated limbic encephalitis. ( Clover, L; Grubneac, A; Irani, SR; Jacob, S; Rajabally, YA; Vincent, A; Walters, RJ; Yazaki, M, 2008)
"Diagnosis of Tachon syndrome is made by elimination of the usual medical and surgical causes, and physicians performing local injections should be aware of this phenomenon."1.34An unusual complication of intra-articular injections of corticosteroids: Tachon syndrome. Two case reports. ( Hajjioui, A; Nys, A; Poiraudeau, S; Revel, M, 2007)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19905 (15.63)18.7374
1990's5 (15.63)18.2507
2000's8 (25.00)29.6817
2010's11 (34.38)24.3611
2020's3 (9.38)2.80

Authors

AuthorsStudies
Al-Hammouri, FA1
Khori, FA1
Abu Qamar, AA1
Nimate, A1
Kaabneh, AB1
Almajali, A1
Zraigat, A1
Alomari, A1
Couzi, E1
Boisson, M1
Segretin, F1
Lefèvre-Colau, MM3
Roren, A1
Moreau, S1
Goret, S1
Poiraudeau, S4
Rannou, F3
Nguyen, C2
Bahar-Ozdemir, Y1
Sencan, S1
Ercalik, T1
Kokar, S1
Gunduz, OH1
Akbari Aghdam, H1
Andalib, A1
Asadiyan Ardakani, H1
Telloo, M1
Sheikhbahaei, E1
Boutron, I1
Baron, G1
Sanchez, K1
Palazzo, C1
Benchimol, R1
Paris, G1
James-Belin, É1
Beaudreuil, J1
Laredo, JD1
Béra-Louville, A1
Cotten, A1
Drapé, JL1
Feydy, A1
Ravaud, P1
Steurer, J1
Fujikawa, T1
Takayama, K1
Deml, MC1
Buhr, M1
Wimmer, MD1
Pflugmacher, R1
Riedel, R1
Rommelspacher, Y1
Kabir, K1
Wong, DR1
Wong, GR1
Moussa, B1
Ang, MT1
Ma, AL1
Lai, WM1
Chiu, MC1
Rice, CM1
Beric, V1
Love, S1
Scolding, NJ1
Blanchais, A1
Le Goff, B1
Guillot, P1
Berthelot, JM1
Glemarec, J1
Maugars, Y1
Thefenne, L1
Dubecq, C1
Zing, E1
Rogez, D1
Soula, M1
Escobar, E1
Defuentes, G1
Lapeyre, E1
Berets, O1
Maigne, JY1
Pigeau, I1
Aguer, N1
Doursounian, L1
Chatellier, G1
LEAO, L1
JANSEN, C2
TAKAYAMA, A1
OGUMA, Y1
YAMANAKA, K1
LINDHOLM, R1
SALENIUS, P1
Benyahya, R1
Fayad, F1
Demaille-Wlodyka, S1
Mayoux-Benhamou, MA1
Revel, M2
Schleinitz, N1
Veit, V1
Coso, D1
Aurran, T1
Berbis, P1
Harle, JR1
Gómez-Puerta, JA1
Musuruana, J1
Saez, C1
Cervera, R1
Font, J1
Schulte, TL1
Pietilä, TA1
Heidenreich, J1
Brock, M1
Stendel, R1
Hajjioui, A1
Nys, A1
Jacob, S1
Irani, SR1
Rajabally, YA1
Grubneac, A1
Walters, RJ1
Yazaki, M1
Clover, L1
Vincent, A1
Mam, MK1
Otsuka, F1
Hayakawa, N1
Ogura, T1
Kataoka, H1
Kawashima, M1
Mimura, Y1
Yamauchi, T1
Kashihara, N1
Kageyama, J1
Makino, H1
Bannwarth, B1
Schaeverbeke, T1
Péhourcq, F1
Vernhes, JP1
D'Yvoire, MB1
Dehais, J1
Dumont, D1
Hariz, H1
Meynieu, P1
Salama, J1
Dreyfus, P1
Boissier, MC1
Avimadje, M1
Goupille, P1
Jeannou, J1
Gouthière, C1
Valat, JP1
Ozaki, D1
Shirai, Y1
Nakayama, Y1
Yoshihara, K1
Huzita, T1
Wittke, R1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evolution of Chronic Low Back Pain of Active Discopathy After Intradiscal Corticosteroid Infiltrations According to Modic 1 Distribution and Association With Degenerative Restructuring[NCT04142580]95 participants (Actual)Observational2019-11-13Completed
Intra-discal Steroid Injection for MODIC I Discopathy: A Randomized Control Trial[NCT00804531]Phase 4137 participants (Actual)Interventional2009-04-30Completed
A Randomized Case Control Study of Pre-emptive Caudal Epidural Analgesia With Ropivacaine With and Without Dexamethasone for Lumbosacral Spine Surgery[NCT05904275]60 participants (Anticipated)Interventional2023-08-01Not yet recruiting
Comparative Study of the Use of Ultrasonography (USG) or Isolated Use of Fluoroscopy for Sacral Epidural Puncture Corticosteroid Infiltration in Patients With Low Back Pain by Canal Stenosis Lumbar[NCT02860078]0 participants (Actual)Interventional2021-01-17Withdrawn (stopped due to Insufficient drug supply)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for prednisolone and Low Back Pain

ArticleYear
A rare case of paraplegia complicating a lumbar epidural infiltration.
    Annals of physical and rehabilitation medicine, 2010, Volume: 53, Issue:9

    Topics: Anti-Inflammatory Agents; Arteries; Embolism; Flushing; Humans; Informed Consent; Injections, Epidur

2010
A case of primary hyperparathyroidism accompanying multiple myeloma.
    Endocrine journal, 1997, Volume: 44, Issue:1

    Topics: Aged; Antineoplastic Agents; Female; Humans; Hypercalcemia; Hyperparathyroidism; Hyperplasia; Low Ba

1997
Can an anomalous lumbo-sacral or lumbo-iliac articulation cause low back pain? A retrospective study of 12 cases.
    Revue du rhumatisme (English ed.), 1999, Volume: 66, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Arthrography; Betamethasone; F

1999

Trials

6 trials available for prednisolone and Low Back Pain

ArticleYear
A short-term oral corticosteroid for refractory lumbar spinal stenosis: a double-blinded randomized placebo-controlled clinical trial.
    International journal of rehabilitation research. Internationale Zeitschrift fur Rehabilitationsforschung. Revue internationale de recherches de readaptation, 2020, Volume: 43, Issue:4

    Topics: Administration, Oral; Disability Evaluation; Double-Blind Method; Female; Glucocorticoids; Humans; L

2020
Intradiscal Glucocorticoid Injection for Patients With Chronic Low Back Pain Associated With Active Discopathy: A Randomized Trial.
    Annals of internal medicine, 2017, Apr-18, Volume: 166, Issue:8

    Topics: Adult; Chronic Pain; Double-Blind Method; Drug Administration Schedule; Female; Glucocorticoids; Hum

2017
Intradiscal Glucocorticoid Injection for Patients With Chronic Low Back Pain Associated With Active Discopathy: A Randomized Trial.
    Annals of internal medicine, 2017, Apr-18, Volume: 166, Issue:8

    Topics: Adult; Chronic Pain; Double-Blind Method; Drug Administration Schedule; Female; Glucocorticoids; Hum

2017
Intradiscal Glucocorticoid Injection for Patients With Chronic Low Back Pain Associated With Active Discopathy: A Randomized Trial.
    Annals of internal medicine, 2017, Apr-18, Volume: 166, Issue:8

    Topics: Adult; Chronic Pain; Double-Blind Method; Drug Administration Schedule; Female; Glucocorticoids; Hum

2017
Intradiscal Glucocorticoid Injection for Patients With Chronic Low Back Pain Associated With Active Discopathy: A Randomized Trial.
    Annals of internal medicine, 2017, Apr-18, Volume: 166, Issue:8

    Topics: Adult; Chronic Pain; Double-Blind Method; Drug Administration Schedule; Female; Glucocorticoids; Hum

2017
    Praxis, 2017, Volume: 106, Issue:14

    Topics: Adult; Aged; Double-Blind Method; France; Humans; Injections, Spinal; Intervertebral Disc; Intervert

2017
[Intradiscal injection of acetate of prednisolone in severe low back pain: complications and patients' assessment of effectiveness].
    Annales de readaptation et de medecine physique : revue scientifique de la Societe francaise de reeducation fonctionnelle de readaptation et de medecine physique, 2004, Volume: 47, Issue:9

    Topics: Adult; Anti-Inflammatory Agents; Calcinosis; Female; Humans; Intervertebral Disc; Intervertebral Dis

2004
Injection therapy of lumbar facet syndrome: a prospective study.
    Acta neurochirurgica, 2006, Volume: 148, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anti-Inflammatory Agents; Drug Combinations; Fem

2006
Prednisolone concentrations in cerebrospinal fluid after oral prednisone. Preliminary data.
    Revue du rhumatisme (English ed.), 1997, Volume: 64, Issue:5

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Blood-Brain Barrier;

1997

Other Studies

23 other studies available for prednisolone and Low Back Pain

ArticleYear
Management of Idiopathic Retroperitoneal Fibrosis, a Retrospective Study at Prince Hussein Urology and Organ transplantation center (PHUO), Jordan.
    Iranian journal of kidney diseases, 2019, Volume: 13, Issue:4

    Topics: Adult; Aged; Female; Glucocorticoids; Humans; Jordan; Low Back Pain; Male; Middle Aged; Prednisolone

2019
Lumbosacral immobilization following glucocorticoid intradiscal injection in patients with chronic low back pain and active discopathy: A feasibility study.
    Journal of back and musculoskeletal rehabilitation, 2020, Volume: 33, Issue:6

    Topics: Adult; Combined Modality Therapy; Feasibility Studies; Female; Glucocorticoids; Humans; Immobilizati

2020
The Effect of Pre-Treatment Depression, Anxiety and Somatization Levels on Transforaminal Epidural Steroid Injection: A Prospective Observational Study.
    Pain physician, 2020, Volume: 23, Issue:3

    Topics: Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents; Anxiety; Bupivacaine; Depression; Female;

2020
Spinal cord abscess and inflammatory bowel disease.
    QJM : monthly journal of the Association of Physicians, 2015, Volume: 108, Issue:3

    Topics: Abscess; Aged; Anti-Inflammatory Agents; Colitis, Ulcerative; Female; Fever; Humans; Low Back Pain;

2015
CT-guided infiltration saves surgical intervention and fastens return to work compared to anatomical landmark-guided infiltration in patients with lumbosciatica.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2015, Volume: 25 Suppl 1

    Topics: Adult; Analgesics; Anatomic Landmarks; Anesthetics, Local; Anti-Inflammatory Agents; Bupivacaine; Fe

2015
Paediatric chronic recurrent multifocal osteomyelitis.
    BMJ case reports, 2017, Mar-09, Volume: 2017

    Topics: Adolescent; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Low B

2017
An unusual case of loin pain and nephritis.
    Clinical and experimental nephrology, 2010, Volume: 14, Issue:1

    Topics: Adolescent; Cyclosporine; DNA; Enoxaparin; Female; Glomerulonephritis, Membranous; Humans; Immunosup

2010
Neurological picture. Vertebral sarcoidosis mimicking metastases.
    Journal of neurology, neurosurgery, and psychiatry, 2011, Volume: 82, Issue:2

    Topics: Anti-Inflammatory Agents; Biopsy; Diagnosis, Differential; Female; Humans; Immunosuppressive Agents;

2011
Feasibility and safety of ultrasound-guided caudal epidural glucocorticoid injections.
    Joint bone spine, 2010, Volume: 77, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Feasibility Studies; Female; Humans; Injections, Epidura

2010
Feasibility and safety of ultrasound-guided caudal epidural glucocorticoid injections.
    Joint bone spine, 2010, Volume: 77, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Feasibility Studies; Female; Humans; Injections, Epidura

2010
Feasibility and safety of ultrasound-guided caudal epidural glucocorticoid injections.
    Joint bone spine, 2010, Volume: 77, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Feasibility Studies; Female; Humans; Injections, Epidura

2010
Feasibility and safety of ultrasound-guided caudal epidural glucocorticoid injections.
    Joint bone spine, 2010, Volume: 77, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Feasibility Studies; Female; Humans; Injections, Epidura

2010
Chronic coccydynia in adolescents. A series of 53 patients.
    European journal of physical and rehabilitation medicine, 2011, Volume: 47, Issue:2

    Topics: Adolescent; Adult; Age Factors; Amitriptyline; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, N

2011
Intradiscal injection of hydrocortisone and prednisolone in the treatment of low back pain.
    Rheumatism, 1960, Volume: 16

    Topics: Back Pain; Humans; Hydrocortisone; Injections; Intervertebral Disc Displacement; Low Back Pain; Pred

1960
[On the treatment of the lumbago-ischial syndrome with a mixed compound injection].
    Munchener medizinische Wochenschrift (1950), 1961, Jun-02, Volume: 103

    Topics: Back Pain; Injections; Ischium; Low Back Pain; Prednisolone; Procaine; Sciatica

1961
[Clinical observations of low back pain over 7 years].
    Nihon Seikeigeka Gakkai zasshi, 1963, Volume: 37

    Topics: Back Pain; Chondroitin; Glucuronates; Humans; Low Back Pain; Osteoarthritis; Osteoporosis; Prednisol

1963
CAUDAL, EPIDURAL ADMINISTRATION OF ANAESTHETICS AND CORTICOIDS IN THE TREATMENT OF LOW BACK PAIN.
    Acta orthopaedica Scandinavica, 1964, Volume: 34

    Topics: Adrenal Cortex Hormones; Anesthesia, Epidural; Anesthesia, Spinal; Anesthetics; Back Pain; Humans; I

1964
[ON IMPROVED CONSERVATIVE TREATMENT OF THE LUMBAGO-SCIATICA SYNDROME].
    Deutsches medizinisches Journal, 1964, Apr-20, Volume: 15

    Topics: Back Pain; Humans; Hyaluronoglucosaminidase; Hydroxocobalamin; Low Back Pain; Prednisolone; Procaine

1964
Drug-induced eosinophilia and systemic symptoms: hypersensitivity or peripheral T-cell lymphoma?
    Archives of dermatology, 2005, Volume: 141, Issue:3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Cyclophosphamide; Diagnosis,

2005
[Sarcoidosis as seronegative spondyloarthropathy].
    Biomedica : revista del Instituto Nacional de Salud, 2005, Volume: 25, Issue:4

    Topics: Adult; Female; Glucocorticoids; Humans; Low Back Pain; Male; Middle Aged; Prednisolone; Radiography,

2005
An unusual complication of intra-articular injections of corticosteroids: Tachon syndrome. Two case reports.
    Annales de readaptation et de medecine physique : revue scientifique de la Societe francaise de reeducation fonctionnelle de readaptation et de medecine physique, 2007, Volume: 50, Issue:9

    Topics: Arthralgia; Elbow Joint; Glucocorticoids; Humans; Injections, Intra-Arterial; Low Back Pain; Male; M

2007
Hypothermia in VGKC antibody-associated limbic encephalitis.
    Journal of neurology, neurosurgery, and psychiatry, 2008, Volume: 79, Issue:2

    Topics: Aged; Atrophy; Autoantibodies; Azathioprine; Cyclosporine; Dominance, Cerebral; Epilepsy, Temporal L

2008
Results of epidural injection of local anaesthetic and corticosteroid in patients with lumbosciatic pain.
    Journal of the Indian Medical Association, 1995, Volume: 93, Issue:1

    Topics: Adult; Aged; Drug Combinations; Female; Humans; Injections, Epidural; Lidocaine; Low Back Pain; Male

1995
Abducens palsy after an intrathecal glucocorticoid injection. Evidence for a role of intracranial hypotension.
    Revue du rhumatisme (English ed.), 1998, Volume: 65, Issue:5

    Topics: Abducens Nerve Injury; Adult; Cranial Nerve Diseases; Female; Glucocorticoids; Humans; Hypotension,

1998
Multiple fish vertebra deformity in child with systemic lupus erythematosus: a case report.
    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2000, Volume: 67, Issue:4

    Topics: Anti-Inflammatory Agents; Bone Density; Bone Diseases, Metabolic; Calcitonin; Child; Female; Humans;

2000
[Emergencies in the practice. Acute lumbago: diagnosis and therapy].
    MMW Fortschritte der Medizin, 2002, Feb-28, Volume: 144, Issue:9

    Topics: Acute Disease; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents; Chiropractic; Diagn

2002