prednisolone has been researched along with Leukemic Infiltration in 17 studies
Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.
Leukemic Infiltration: A pathologic change in leukemia in which leukemic cells permeate various organs at any stage of the disease. All types of leukemia show various degrees of infiltration, depending upon the type of leukemia. The degree of infiltration may vary from site to site. The liver and spleen are common sites of infiltration, the greatest appearing in myelocytic leukemia, but infiltration is seen also in the granulocytic and lymphocytic types. The kidney is also a common site and of the gastrointestinal system, the stomach and ileum are commonly involved. In lymphocytic leukemia the skin is often infiltrated. The central nervous system too is a common site.
| Excerpt | Relevance | Reference |
|---|---|---|
| " There is increasing evidence that, even in equipotent dosage for glucocorticoid effect, dexamethasone has enhanced lymphoblast cytotoxicity and penetration of the central nervous system (CNS) compared with prednisolone." | 2.71 | Benefit of dexamethasone compared with prednisolone for childhood acute lymphoblastic leukaemia: results of the UK Medical Research Council ALL97 randomized trial. ( Eden, TO; Kinsey, SE; Lilleyman, J; Mitchell, CD; Richards, SM; Vora, A, 2005) |
| "Although renal failure due to leukemic infiltration has been described in many cases of acute leukemia, only 11 cases of renal failure due to CLL cells' infiltration have been described in the literature." | 1.36 | Renal dysfunction due to leukemic infiltration of kidneys in a case of chronic lymphocytic leukemia. ( Brum, S; Carvalho, D; Carvalho, F; Ferreira, AC; Pataca, I; Santos, JR; Santos, MC, 2010) |
| "Infiltration of ATLL into the thoracic cord was diagnosed." | 1.32 | [Successful radiotherapy for the thoracic cord infiltration of adult T-cell leukemia/lymphoma]. ( Akiyama, N; Hayama, M; Higashihara, M; Horie, R; Kajiwara, K; Kohri, M; Niitsu, N; Ohtake, H; Ohwada, A; Taira, M, 2003) |
| "Treatment with chlorambucil, prednisolone, and renal bed irradiation resulted in a substantial improvement in renal function which persisted until the the patient's death from marrow failure some eight years later." | 1.29 | Renal failure caused by leukaemic infiltration in chronic lymphocytic leukaemia. ( Bass, PS; Davies, DR; Jones, NF; Majumdar, G; Pearson, TC; Phillips, JK, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (35.29) | 18.2507 |
| 2000's | 9 (52.94) | 29.6817 |
| 2010's | 2 (11.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, SM | 1 |
| Lee, WS | 1 |
| Shin, HJ | 1 |
| Lee, JJ | 1 |
| Sohn, SK | 1 |
| Moon, JH | 1 |
| Eom, HS | 1 |
| Won, JH | 1 |
| Lee, KH | 1 |
| Lee, JH | 2 |
| Kim, DY | 1 |
| Yoon, SS | 1 |
| Kim, I | 1 |
| Jung, CW | 1 |
| Kim, SJ | 1 |
| Kim, H | 1 |
| Ryoo, HM | 1 |
| Lee, GW | 1 |
| Kim, SH | 1 |
| Mun, YC | 1 |
| Kim, MK | 1 |
| Joo, YD | 1 |
| Ferreira, AC | 1 |
| Brum, S | 1 |
| Carvalho, D | 1 |
| Pataca, I | 1 |
| Carvalho, F | 1 |
| Santos, MC | 1 |
| Santos, JR | 1 |
| Aktan, M | 1 |
| Akkaya, A | 1 |
| Doğan, O | 1 |
| Dincol, G | 1 |
| Akiyama, N | 1 |
| Ohtake, H | 1 |
| Ohwada, A | 1 |
| Kajiwara, K | 1 |
| Hayama, M | 1 |
| Kohri, M | 1 |
| Taira, M | 1 |
| Niitsu, N | 1 |
| Horie, R | 1 |
| Higashihara, M | 1 |
| Mitchell, CD | 1 |
| Richards, SM | 1 |
| Kinsey, SE | 1 |
| Lilleyman, J | 1 |
| Vora, A | 1 |
| Eden, TO | 1 |
| Yamada, Y | 1 |
| Aguilera Cros, C | 1 |
| Gutierrez, I | 1 |
| Gómez, JP | 1 |
| Lin, WY | 1 |
| Liu, HC | 1 |
| Yeh, TC | 1 |
| Wang, LY | 1 |
| Liang, DC | 1 |
| Whittle, AM | 1 |
| Howard, MR | 1 |
| Suzuki, H | 1 |
| Suzuki, T | 1 |
| Kamijo, A | 1 |
| Oota, S | 1 |
| Sato, H | 1 |
| Hangaishi, A | 1 |
| Takahashi, T | 1 |
| Kanda, Y | 1 |
| Motokura, T | 1 |
| Chiba, S | 1 |
| Kurokawa, M | 1 |
| Reiter, A | 1 |
| Yamamoto, N | 1 |
| Kiyosawa, M | 1 |
| Kawasaki, T | 1 |
| Miki, T | 1 |
| Fujino, T | 1 |
| Tokoro, T | 1 |
| Hirano, T | 1 |
| Tomiyoshi, K | 1 |
| Take, H | 1 |
| Watanabe, N | 1 |
| Oriuchi, N | 1 |
| Inoue, T | 1 |
| Naruse, M | 1 |
| Endo, K | 1 |
| Shiga, Y | 1 |
| Shichishima, T | 1 |
| Aikawa, K | 1 |
| Gotoh, J | 1 |
| Furukawa, T | 1 |
| Yamagiwa, A | 1 |
| Ishibashi, T | 1 |
| Maruyama, Y | 1 |
| Phillips, JK | 1 |
| Bass, PS | 1 |
| Majumdar, G | 1 |
| Davies, DR | 1 |
| Jones, NF | 1 |
| Pearson, TC | 1 |
| Niehues, T | 1 |
| Kapaun, P | 1 |
| Harms, DO | 1 |
| Burdach, S | 1 |
| Kramm, C | 1 |
| Körholz, D | 1 |
| Janka-Schaub, G | 1 |
| Göbel, U | 1 |
| Várkonyi, J | 1 |
| Zalatnai, A | 1 |
| Timár, J | 1 |
| Matolcsi, A | 1 |
| Falus, A | 1 |
| Bencsáth, M | 1 |
| László, V | 1 |
| Pócsik, E | 1 |
| Kotlán, B | 1 |
| Császár, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Medical Research Council Working Party on Leukaemia in Children UK National Lymphoblastic Leukaemia (ALL) Trial[NCT00003437] | Phase 3 | 1,800 participants (Anticipated) | Interventional | 1997-01-31 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for prednisolone and Leukemic Infiltration
| Article | Year |
|---|---|
[Progress of the ATLL study: an overview].
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carboplatin; Cyclin-Dependent Kinase Inhi | 2005 |
Therapy of B-cell acute lymphoblastic leukaemia in childhood: the BFM experience.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Burkitt Lymphoma; Child; Child, Preschoo | 1994 |
[A case of acute nonlymphocytic leukemia with leukemic cell infiltration to the uterus followed by bone marrow relapse].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Female; | 1994 |
2 trials available for prednisolone and Leukemic Infiltration
| Article | Year |
|---|---|
Escalated daunorubicin dosing as an induction treatment for Philadelphia-negative adult acute lymphoblastic leukemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Central Nervo | 2013 |
Benefit of dexamethasone compared with prednisolone for childhood acute lymphoblastic leukaemia: results of the UK Medical Research Council ALL97 randomized trial.
Topics: Adolescent; Age Factors; Central Nervous System; Child; Child, Preschool; Dexamethasone; Disease-Fre | 2005 |
12 other studies available for prednisolone and Leukemic Infiltration
| Article | Year |
|---|---|
Renal dysfunction due to leukemic infiltration of kidneys in a case of chronic lymphocytic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Female; Humans; Kidney; Leukemia, | 2010 |
Chronic lymphocytic leukemia and multiple myeloma in the same patient: case report.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; B-Lymphocytes; Bone Neoplasms; Chlorambucil; C | 2003 |
[Successful radiotherapy for the thoracic cord infiltration of adult T-cell leukemia/lymphoma].
Topics: Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Female; Humans; Leukemia-Lymphoma, Ad | 2003 |
Leukemic infiltration of the knee.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Fatal Outcome; Humans; Hydroxyurea | 2006 |
Triple intrathecal therapy without cranial irradiation for central nervous system preventive therapy in childhood acute lymphoblastic leukemia.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Central Nervous System; Ch | 2008 |
Skin lesions in plasmacytoid dendritic cell leukaemia.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dendritic Cells; Doxorubicin | 2008 |
Antileukemic immunity associated with antineutrophil antibody production after allogeneic hematopoietic SCT for myeloid/NK-cell precursor acute leukemia.
Topics: Adult; Autoantibodies; Dexamethasone; Graft vs Leukemia Effect; Hematopoietic Stem Cell Transplantat | 2008 |
Successfully treated optic nerve infiltration with adult T-cell lymphoma.
Topics: Female; Human T-lymphotropic virus 1; Humans; Leukemia-Lymphoma, Adult T-Cell; Leukemic Infiltration | 1994 |
Reversible functional asplenia. Autoimmune hemolytic anemia with thrombocytopenia in chronic lymphocytic leukemia.
Topics: Anemia, Hemolytic, Autoimmune; Erythrocytes; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; | 1994 |
Renal failure caused by leukaemic infiltration in chronic lymphocytic leukaemia.
Topics: Chlorambucil; Combined Modality Therapy; Humans; Kidney; Kidney Failure, Chronic; Leukemia, Lymphocy | 1993 |
A classification based on T cell selection-related phenotypes identifies a subgroup of childhood T-ALL with favorable outcome in the COALL studies.
Topics: Adolescent; Antigens, CD; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Aspara | 1999 |
Secondary cutaneous infiltration in B cell chronic lymphocytic leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamide; Doxorubicin; Histidi | 2000 |