Page last updated: 2024-11-06

prednisolone and Leg Ulcer

prednisolone has been researched along with Leg Ulcer in 34 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Leg Ulcer: Ulceration of the skin and underlying structures of the lower extremity. About 90% of the cases are due to venous insufficiency (VARICOSE ULCER), 5% to arterial disease, and the remaining 5% to other causes.

Research Excerpts

ExcerptRelevanceReference
"The association of lower leg ulcer development and hydroxyurea therapy in patients with myeloproliferative disorders has been reported previously."7.71Aggressive, extensive, vasculitic leg ulceration associated with hydroxyurea therapy and a fatal outcome. ( Kirby, B; Stewart, EJ; Young, HS, 2001)
"The association of lower leg ulcer development and hydroxyurea therapy in patients with myeloproliferative disorders has been reported previously."3.71Aggressive, extensive, vasculitic leg ulceration associated with hydroxyurea therapy and a fatal outcome. ( Kirby, B; Stewart, EJ; Young, HS, 2001)
"High doses of orally administered prednisolone induced the healing of the pyoderma gangrenosum within 2 months."3.70[Extra-intestinal manifestations and complications in chronic active ulcerative colitis in childhood and adolescence]. ( Hüppe, D; Schenck, B; Tromm, A, 1999)
"Sarcoidosis is a multisystemic disease of unknown etiology."1.43Multisystemic Sarcoidosis Presenting as Pretibial Leg Ulcers. ( Baunacke, A; Hansel, G; Wollina, U, 2016)
" In the present case, re-epithelization and healthy granulation were induced by the CDS without increasing the dosage of systemic prednisolone."1.35Case report: a case of pyoderma gangrenosum with intractable leg ulcers treated by allogeneic cultured dermal substitutes. ( Furukawa, F; Kanazawa, N; Kishioka, A; Kuroyanagi, Y; Matsumoto, Y; Nishide, T; Toyozawa, S; Yamamoto, Y, 2008)
"Leg ulcerations can occur in systemic lupus erythematosus (SLE) patients with antiphospholipid (aPL) antibodies and/or vasculitis, and it has been suggested that aPL antibodies may play a pathogenetic role in skin manifestations of SLE."1.34Lupus and leg ulcers--a diagnostic quandary. ( Boyce, S; Dziadzio, M; Hamdulay, S; Keat, A; Prasad, N; Reddy, V, 2007)
"Prednisolone 80 mg/day was started."1.31Atypical hemorrhagic bullous pyoderma gangrenosum. ( Altunay, IK; Baş, L; Ekmekçi, TR; Ileri, U; Köşlü, A; Kuran, I; Sezgin, SA, 2001)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199011 (32.35)18.7374
1990's4 (11.76)18.2507
2000's10 (29.41)29.6817
2010's8 (23.53)24.3611
2020's1 (2.94)2.80

Authors

AuthorsStudies
Sah, BK1
Chaudhary, S1
Pahari, A1
Ghimire, A1
Sah, RK1
Sah, AK1
Kumari, N1
Jaiswal, YK1
Sah, VK1
Bostan, E1
Akdogan, N1
Saglam Ayhan, A1
Ersoy Evans, S1
Watanabe, M1
Natsuga, K1
Ota, M1
Ito, K1
Kamio, Y1
Kanazawa, N2
Mine, Y1
Utani, A1
Wollina, U1
Baunacke, A1
Hansel, G1
Ichiki, Y1
Kitajima, Y1
Toyozawa, S1
Yamamoto, Y1
Nishide, T1
Kishioka, A1
Matsumoto, Y1
Kuroyanagi, Y1
Furukawa, F1
Seitz, CS1
Berens, N1
Bröcker, EB1
Trautmann, A1
Lui, NL1
Thumboo, J1
Fong, KY1
Wei, CH1
Huang, YH1
Shih, YC1
Tseng, FW1
Yang, CH1
Rozin, AP2
Egozi, D1
Ramon, Y1
Toledano, K1
Braun-Moscovici, Y1
Markovits, D1
Schapira, D1
Bergman, R1
Melamed, Y1
Ullman, Y1
Balbir-Gurman, A2
Kluger, N1
Girard, C1
Durand, L1
Bessis, D1
Guillot, B1
CHATELIER, A1
SZEGOE, L1
PALLIS, CA1
SCOTT, JT1
Gilead, L1
Slodownik, D1
Barlas, S1
Tansel, T1
Reddy, V1
Dziadzio, M1
Hamdulay, S1
Boyce, S1
Prasad, N1
Keat, A1
Alekhin, DI1
Fokin, AA1
Mikhaĭlova, OA1
Sumnaia, DB1
Goloshchapova, ZhA1
Lamberty, BG1
Hüppe, D1
Schenck, B1
Tromm, A1
Umezawa, Y1
Oyake, S1
Oh-i, T1
Nagae, T1
Ishimaru, S1
Altunay, IK1
Sezgin, SA1
Ileri, U1
Ekmekçi, TR1
Kuran, I1
Köşlü, A1
Baş, L1
Young, HS1
Kirby, B1
Stewart, EJ1
Harland, CC1
Kilby, PE1
Dunkel, FG1
Elsner, P1
Burg, G1
Rustin, MH1
Gilkes, JJ1
Robinson, TW1
Peter, L1
Hoppe-Seyler, G1
Nurse, DS1
Montgomery, PR1
Morton, EV1
Liakhovich, VM1
Haeger, K1

Reviews

3 reviews available for prednisolone and Leg Ulcer

ArticleYear
Ulcerative sarcoidosis: case report and review of the Japanese literature.
    Acta dermato-venereologica, 2008, Volume: 88, Issue:5

    Topics: Biopsy; Glucocorticoids; Granuloma; Humans; Japan; Langerhans Cells; Leg Ulcer; Male; Middle Aged; P

2008
Leg ulceration in rheumatoid arthritis--an underreported multicausal complication with considerable morbidity: analysis of thirty-six patients and review of the literature.
    Dermatology (Basel, Switzerland), 2010, Volume: 220, Issue:3

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthritis, Rheumatoid; Etoricoxib; Female; Gram-Posi

2010
Combined therapy for pyoderma gangrenosum.
    Annals of the rheumatic diseases, 2004, Volume: 63, Issue:7

    Topics: Aged; Cyclophosphamide; Cyclosporine; Drug Therapy, Combination; Female; Humans; Immunosuppressive A

2004

Other Studies

31 other studies available for prednisolone and Leg Ulcer

ArticleYear
Dysentery and leg ulcer as an atypical presentation of systemic lupus erythematosus: A case report.
    Medicine, 2022, Dec-16, Volume: 101, Issue:50

    Topics: Adolescent; Antibodies, Antinuclear; Child; Dysentery; Female; Fever; Humans; Leg Ulcer; Leukopenia;

2022
Widespread primary cutaneous diffuse large B-cell lymphoma, leg type, with nasal involvement.
    International wound journal, 2019, Volume: 16, Issue:4

    Topics: Aged, 80 and over; Antineoplastic Agents; Humans; Leg Ulcer; Lymphoma, Large B-Cell, Diffuse; Male;

2019
Pyoderma Gangrenosum Associated with Acute Respiratory Distress Syndrome.
    The American journal of medicine, 2016, Volume: 129, Issue:2

    Topics: Diagnosis, Differential; Glucocorticoids; Humans; Leg Ulcer; Male; Middle Aged; Prednisolone; Pyoder

2016
Intractable leg ulcers in Blau syndrome.
    The Journal of dermatology, 2016, Volume: 43, Issue:9

    Topics: Arthritis; Arthritis, Rheumatoid; Behcet Syndrome; Biopsy; Erythema Nodosum; Female; Glucocorticoids

2016
Multisystemic Sarcoidosis Presenting as Pretibial Leg Ulcers.
    The international journal of lower extremity wounds, 2016, Volume: 15, Issue:3

    Topics: Anti-Inflammatory Agents; Biopsy; Diagnosis, Differential; Female; Granuloma; Humans; Leg Ulcer; Lym

2016
Case report: a case of pyoderma gangrenosum with intractable leg ulcers treated by allogeneic cultured dermal substitutes.
    Dermatology online journal, 2008, Nov-15, Volume: 14, Issue:11

    Topics: Aged; Arthritis, Rheumatoid; Cells, Cultured; Combined Modality Therapy; Debridement; Female; Fibrob

2008
A case of refractory vasculitic ulcers in a systemic lupus erythematosus patient responding to rituximab and hyperbaric oxygen therapy.
    International journal of rheumatic diseases, 2009, Volume: 12, Issue:4

    Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Drug Therapy, Combination; Fe

2009
Sarcoidosis with cutaneous granulomatous vasculitis.
    The Australasian journal of dermatology, 2010, Volume: 51, Issue:3

    Topics: Adult; Azathioprine; Granuloma, Giant Cell; Humans; Leg Ulcer; Male; Prednisolone; Sarcoidosis; Syst

2010
Large leg ulcers due to autoimmune diseases.
    Medical science monitor : international medical journal of experimental and clinical research, 2011, Volume: 17, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Autoimmune Diseases; Azathioprine; Ciprofloxacin; Cyclophosphamide;

2011
Leg ulcers revealing systemic sarcoidosis with splenomegaly and thrombocytopenia.
    International journal of dermatology, 2013, Volume: 52, Issue:11

    Topics: Adult; Anti-Inflammatory Agents; Humans; Leg Ulcer; Male; Prednisolone; Sarcoidosis; Splenomegaly; T

2013
Intra-articular steroids and destructive arthropathy.
    Lancet (London, England), 1963, Jan-05, Volume: 1, Issue:7271

    Topics: Administration, Topical; Digitoxin; Humans; Joint Diseases; Leg Ulcer; Prednisolone; Prednisone; Ste

1963
THE USE OF PREDNISOLONE-IODOCHLOROXYQUINOLINE IN THE TREATMENT OF ULCERS OF THE SKIN.
    Therapia Hungarica (English edition), 1963, Volume: 11

    Topics: Administration, Topical; Child; Clioquinol; Drug Therapy; Escherichia coli Infections; Geriatrics; H

1963
PERIPHERAL NEUROPATHY IN RHEUMATOID ARTHRITIS.
    British medical journal, 1965, May-01, Volume: 1, Issue:5443

    Topics: Agglutination; Angiography; Arteritis; Arthritis; Arthritis, Rheumatoid; Brachial Artery; Classifica

1965
Antiphospholipid syndrome in a child: an insight into the pathology, identification, and means of cure.
    Journal of pediatric surgery, 2004, Volume: 39, Issue:8

    Topics: Antibodies, Anticardiolipin; Anticoagulants; Antiphospholipid Syndrome; Arterial Occlusive Diseases;

2004
Lupus and leg ulcers--a diagnostic quandary.
    Clinical rheumatology, 2007, Volume: 26, Issue:7

    Topics: Adult; Azathioprine; Drug Therapy, Combination; Glucocorticoids; Humans; Immunosuppressive Agents; L

2007
[Administration of prostaglandins Ei and immunotherapy in management of various-genesis trophic ulcers].
    Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery, 2007, Volume: 13, Issue:3

    Topics: Administration, Oral; Alprostadil; Anti-Inflammatory Agents, Non-Steroidal; Chloroquine; Chronic Dis

2007
Pyoderma gangrenosum: report of an unusual case and a review of the literature.
    The Journal of dermatologic surgery and oncology, 1981, Volume: 7, Issue:1

    Topics: Azathioprine; Female; Humans; Leg Ulcer; Middle Aged; Necrosis; Prednisolone; Pyoderma; Skin; Staphy

1981
[Extra-intestinal manifestations and complications in chronic active ulcerative colitis in childhood and adolescence].
    Deutsche medizinische Wochenschrift (1946), 1999, Jul-09, Volume: 124, Issue:27

    Topics: Adolescent; Azathioprine; Budesonide; Child; Colitis, Ulcerative; Diagnosis, Differential; Drug Ther

1999
A case of pyoderma gangrenosum on the stump of an amputated right leg.
    The Journal of dermatology, 2000, Volume: 27, Issue:8

    Topics: Aged; Amputation Stumps; Amputation, Surgical; Anti-Inflammatory Agents; Arterial Occlusive Diseases

2000
Atypical hemorrhagic bullous pyoderma gangrenosum.
    International journal of dermatology, 2001, Volume: 40, Issue:5

    Topics: Anti-Inflammatory Agents; Biopsy; Female; Humans; Leg Ulcer; Middle Aged; Prednisolone; Pyoderma Gan

2001
Aggressive, extensive, vasculitic leg ulceration associated with hydroxyurea therapy and a fatal outcome.
    Clinical and experimental dermatology, 2001, Volume: 26, Issue:8

    Topics: Aged; Cyclophosphamide; Fatal Outcome; Female; Foot Ulcer; Glucocorticoids; Humans; Hydroxyurea; Imm

2001
Vasculitis in association with atherosclerosis.
    The British journal of dermatology, 1992, Volume: 126, Issue:1

    Topics: Arteriosclerosis; Humans; Leg Ulcer; Male; Middle Aged; Prednisolone; Vasculitis

1992
Allergic contact dermatitis from prednicarbate.
    Contact dermatitis, 1991, Volume: 24, Issue:1

    Topics: Aged; Anti-Inflammatory Agents; Dermatitis, Contact; Female; Humans; Leg Ulcer; Prednisolone; Recurr

1991
Pyoderma gangrenosum associated with Behçet's disease: treatment with thalidomide.
    Journal of the American Academy of Dermatology, 1990, Volume: 23, Issue:5 Pt 1

    Topics: Adult; Behcet Syndrome; Gangrene; Humans; Leg Ulcer; Male; Prednisolone; Pyoderma; Recurrence; Thali

1990
[Necrotizing circumscribed scleroderma after cupping therapy in arterial occlusion].
    Zeitschrift fur Hautkrankheiten, 1986, Jul-01, Volume: 61, Issue:13

    Topics: Arterial Occlusive Diseases; Chloroquine; Humans; Leg; Leg Ulcer; Male; Middle Aged; Prednisolone; S

1986
[Local treatment of congestive erythema, with special attention to marginal ulcer].
    Zeitschrift fur Haut- und Geschlechtskrankheiten, 1967, Jun-01, Volume: 42, Issue:11

    Topics: Administration, Topical; Anti-Inflammatory Agents; Chloramphenicol; Dermatologic Agents; Erythema; H

1967
Livedo reticularis with ulceration: response to azathioprine therapy.
    The Australasian journal of dermatology, 1974, Volume: 15, Issue:2

    Topics: Azathioprine; Drug Therapy, Combination; Humans; Leg Dermatoses; Leg Ulcer; Male; Middle Aged; Predn

1974
Leg ulcer with rheumatoid disease treated by systemic prednisolone.
    The British journal of dermatology, 1970, Volume: 83, Issue:1

    Topics: Arthritis, Rheumatoid; Female; Humans; Leg Ulcer; Middle Aged; Prednisolone

1970
Peripheral vascular disease in the elderly.
    The Practitioner, 1971, Volume: 206, Issue:233

    Topics: Aged; Female; Giant Cell Arteritis; Humans; Leg Ulcer; Male; Occlusive Dressings; Prednisolone; Thro

1971
[Treatment of trophic ulcers of the lower extremities with prednisolone and vitamin A].
    Klinicheskaia khirurgiia, 1967, Volume: 7

    Topics: Disability Evaluation; Humans; Leg Ulcer; Occupational Medicine; Prednisolone; Vitamin A

1967
Effects of anabolic steroids in the long-term treatment of ischaemic leg ulcers.
    Zentralblatt fur Phlebologie, 1968, Aug-15, Volume: 7, Issue:3

    Topics: Anabolic Agents; Animals; Collagen Diseases; Female; Glucocorticoids; Humans; Ischemia; Leg Ulcer; M

1968