Page last updated: 2024-11-06

prednisolone and Kawasaki Disease

prednisolone has been researched along with Kawasaki Disease in 54 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Research Excerpts

ExcerptRelevanceReference
"Prednisolone (PSL) has been suggested to be useful for the treatment of Kawasaki disease (KD) resistant to i."9.24Targeted use of prednisolone with the second IVIG dose for refractory Kawasaki disease. ( Akiyama, N; Asakura, I; Fukuoka, T; Harazaki, M; Iwashima, S; Kamimaki, T; Kimura, M; Meguro, T; Morishita, H; Ohkawara, I; Sakai, H; Seto, S; Shimomura, M; Tsurui, S, 2017)
" Patients with severe Kawasaki disease were randomly assigned by a minimisation method to receive either intravenous immunoglobulin (2 g/kg for 24 h and aspirin 30 mg/kg per day) or intravenous immunoglobulin plus prednisolone (the same intravenous immunoglobulin regimen as the intravenous immunoglobulin group plus prednisolone 2 mg/kg per day given over 15 days after concentrations of C-reactive protein normalised)."9.16Efficacy of immunoglobulin plus prednisolone for prevention of coronary artery abnormalities in severe Kawasaki disease (RAISE study): a randomised, open-label, blinded-endpoints trial. ( Arakawa, H; Fukazawa, R; Furuno, K; Fuse, S; Hamaoka, K; Hara, S; Hara, T; Ichida, F; Kato, T; Kobayashi, T; Miura, M; Morikawa, A; Nakamura, T; Nomura, Y; Ogawa, C; Ogawa, S; Otani, T; Saji, T; Seki, M; Takatsuki, S; Takeuchi, K; Tokunaga, H, 2012)
"Prednisolone therapy for acute phase Kawasaki disease had been considered to be controversial for several decades."8.90[Prednisolone therapy for Kawasaki disease]. ( Arakawa, H; Kobayashi, T, 2014)
" Patients who were febrile at diagnosis received primary IVIG (2 g/kg per 24 h) and oral aspirin (30 mg/kg per day) until the fever resolved, followed by oral aspirin (5 mg/kg per day) for 2 months after Kawasaki disease onset."7.88Efficacy and safety of intravenous immunoglobulin plus prednisolone therapy in patients with Kawasaki disease (Post RAISE): a multicentre, prospective cohort study. ( Chiga, M; Hori, N; Kaneko, T; Komiyama, O; Matsushima, T; Misawa, M; Miura, M; Miyata, K; Morikawa, Y; Nakazawa, M; Obonai, T; Sakakibara, H; Takahashi, T; Tamame, T; Tsuchihashi, T; Yamagishi, H; Yamashita, Y, 2018)
"To identify the prevalence of bradycardia associated with use of prednisolone in patients with Kawasaki disease and analyze the association between bradycardia and responsiveness to intravenous immunoglobulin (IVIG)."7.85Bradycardia Associated with Prednisolone in Children with Severe Kawasaki Disease. ( Miura, M; Morikawa, Y; Nagakura, A; Sakakibara, H, 2017)
"Combination treatment with intravenous immunoglobulin (IVIG) plus prednisolone, newly designed for children with severe Kawasaki disease (KD), reduces coronary artery abnormalities significantly."7.81High incidence of adrenal suppression in children with Kawasaki disease treated with intravenous immunoglobulin plus prednisolone. ( Goto, M; Hasegawa, Y; Kikunaga, K; Miura, M; Miyagawa, N, 2015)
"We reported previously that intravenous immunoglobulin (IVIG) plus prednisolone for initial therapy for Kawasaki disease (KD) prevented coronary artery abnormalities (CAA) more effectively than IVIG alone."7.75Risk stratification in the decision to include prednisolone with intravenous immunoglobulin in primary therapy of Kawasaki disease. ( Arakawa, H; Inoue, Y; Kobayashi, T; Miura, M; Morikawa, A; Ogawa, S; Otani, T; Saji, T; Sonobe, T; Takeuchi, K, 2009)
"We report on 7 patients with severe, complicated Kawasaki disease treated with oral prednisolone, after apparently unsuccessful intravenous immunoglobulin treatment."7.70Treatment of severe complicated Kawasaki disease with oral prednisolone and aspirin. ( Dale, RC; Daw, S; Dillon, MJ; Saleem, MA, 2000)
" We were unable to draw any conclusions regarding acute coronary syndromes, mortality, or length of hospital stay, or for the comparison IVIG versus prednisolone."5.41Intravenous immunoglobulin for the treatment of Kawasaki disease. ( Broderick, C; Ito, S; Kobayashi, S; Kobayashi, T; Suto, M, 2023)
"Prednisolone (PSL) has been suggested to be useful for the treatment of Kawasaki disease (KD) resistant to i."5.24Targeted use of prednisolone with the second IVIG dose for refractory Kawasaki disease. ( Akiyama, N; Asakura, I; Fukuoka, T; Harazaki, M; Iwashima, S; Kamimaki, T; Kimura, M; Meguro, T; Morishita, H; Ohkawara, I; Sakai, H; Seto, S; Shimomura, M; Tsurui, S, 2017)
" Patients with severe Kawasaki disease were randomly assigned by a minimisation method to receive either intravenous immunoglobulin (2 g/kg for 24 h and aspirin 30 mg/kg per day) or intravenous immunoglobulin plus prednisolone (the same intravenous immunoglobulin regimen as the intravenous immunoglobulin group plus prednisolone 2 mg/kg per day given over 15 days after concentrations of C-reactive protein normalised)."5.16Efficacy of immunoglobulin plus prednisolone for prevention of coronary artery abnormalities in severe Kawasaki disease (RAISE study): a randomised, open-label, blinded-endpoints trial. ( Arakawa, H; Fukazawa, R; Furuno, K; Fuse, S; Hamaoka, K; Hara, S; Hara, T; Ichida, F; Kato, T; Kobayashi, T; Miura, M; Morikawa, A; Nakamura, T; Nomura, Y; Ogawa, C; Ogawa, S; Otani, T; Saji, T; Seki, M; Takatsuki, S; Takeuchi, K; Tokunaga, H, 2012)
"Prednisolone therapy for acute phase Kawasaki disease had been considered to be controversial for several decades."4.90[Prednisolone therapy for Kawasaki disease]. ( Arakawa, H; Kobayashi, T, 2014)
" Patients who were febrile at diagnosis received primary IVIG (2 g/kg per 24 h) and oral aspirin (30 mg/kg per day) until the fever resolved, followed by oral aspirin (5 mg/kg per day) for 2 months after Kawasaki disease onset."3.88Efficacy and safety of intravenous immunoglobulin plus prednisolone therapy in patients with Kawasaki disease (Post RAISE): a multicentre, prospective cohort study. ( Chiga, M; Hori, N; Kaneko, T; Komiyama, O; Matsushima, T; Misawa, M; Miura, M; Miyata, K; Morikawa, Y; Nakazawa, M; Obonai, T; Sakakibara, H; Takahashi, T; Tamame, T; Tsuchihashi, T; Yamagishi, H; Yamashita, Y, 2018)
"To identify the prevalence of bradycardia associated with use of prednisolone in patients with Kawasaki disease and analyze the association between bradycardia and responsiveness to intravenous immunoglobulin (IVIG)."3.85Bradycardia Associated with Prednisolone in Children with Severe Kawasaki Disease. ( Miura, M; Morikawa, Y; Nagakura, A; Sakakibara, H, 2017)
"Combination treatment with intravenous immunoglobulin (IVIG) plus prednisolone, newly designed for children with severe Kawasaki disease (KD), reduces coronary artery abnormalities significantly."3.81High incidence of adrenal suppression in children with Kawasaki disease treated with intravenous immunoglobulin plus prednisolone. ( Goto, M; Hasegawa, Y; Kikunaga, K; Miura, M; Miyagawa, N, 2015)
"We reported previously that intravenous immunoglobulin (IVIG) plus prednisolone for initial therapy for Kawasaki disease (KD) prevented coronary artery abnormalities (CAA) more effectively than IVIG alone."3.75Risk stratification in the decision to include prednisolone with intravenous immunoglobulin in primary therapy of Kawasaki disease. ( Arakawa, H; Inoue, Y; Kobayashi, T; Miura, M; Morikawa, A; Ogawa, S; Otani, T; Saji, T; Sonobe, T; Takeuchi, K, 2009)
"Six patients with Kawasaki disease (KD) were treated with prednisolone (1 to 2 mg/kg/day) for 3 days (from days 10 to 12 after the onset of the illness) after apparently unsuccessful treatment with intravenous immunoglobulin (IVIG, 2 g/kg/dose and additional 1 g/kg/dose)."3.73Standard-dose and short-term corticosteroid therapy in immunoglobulin-resistant Kawasaki disease. ( Kawamura, Y; Nakatani, K; Takeshita, S; Tokutomi, T; Tsujimoto, H, 2005)
"We report on 7 patients with severe, complicated Kawasaki disease treated with oral prednisolone, after apparently unsuccessful intravenous immunoglobulin treatment."3.70Treatment of severe complicated Kawasaki disease with oral prednisolone and aspirin. ( Dale, RC; Daw, S; Dillon, MJ; Saleem, MA, 2000)
"Ninety-two patients with Kawasaki disease were treated with five different types of drug therapy: a steroid preparation (prednisolone), aspirin, an antibiotic, a combination of steroid plus aspirin, and a combination of steroid plus warfarin."3.66Kawasaki disease: effect of treatment on coronary artery involvement. ( Kato, H; Koike, S; Yokoyama, T, 1979)
"Although there is ample evidence that Kawasaki disease (KD) is associated with vascular inflammation, few studies have addressed the influence of oxidative stress."2.77Regulation of oxidative stress in patients with Kawasaki disease. ( Arakawa, H; Inoue, Y; Kobayashi, T; Matsuda, S; Mochizuki, H; Sekine, K; Suganuma, E, 2012)
"Serum from patients with coronary aneurysms was less active in stimulating HUVEC tube formation than serum from patients without coronary aneurysms or febrile controls."2.73Impairment of angiogenic activity in the serum from patients with coronary aneurysms due to Kawasaki disease. ( Hamada, H; Higashi, K; Honda, T; Kanazawa, M; Kohno, Y; Terai, M, 2007)
"A total of 277 patients with Kawasaki disease were included in this study."1.72Stratified therapy for Kawasaki disease using a new scoring system to predict the response to a lower dose of intravenous immunoglobulin therapy. ( Hirakubo, Y; Ichihashi, K; Makita, E; Matsuura, M; Nonaka, K; Sugawara, D; Yamashita, S, 2022)
"We describe a case of intussusception followed by KD in a 3-year-old boy."1.62A Case of Kawasaki Disease with Intussusception. ( Abe, M; Asano, T; Fujita, A; Fukunaga, R; Ito, Y; Matsui, R; Miyatake-Sudoh, C; Ueharu, K; Yoshida, K, 2021)
"Thrombocytopenia was seen in 11 patients."1.62Macrophage activation syndrome in children with Kawasaki disease: an experience from a tertiary care hospital in northwest India. ( Gupta, A; Jindal, AK; Johnson, N; Pilania, RK; Prithvi, A; Rawat, A; Singh, S; Suri, D; Vignesh, P, 2021)
"Predominant conditions included juvenile idiopathic arthritis (JIA), juvenile systemic lupus erythematosus (JSLE) and juvenile dermatomyositis (JDM)."1.56Spectrum of paediatric rheumatic disorders at a tertiary hospital in Tanzania. ( Furia, FF; Godfrey, E; Mwamanenge, N; Swai, P, 2020)
"We report a 10-month-old infant with Kawasaki disease who was treated with high-dose IVIg and developed severe HA."1.46Severe Hemolytic Anemia Following Intravenous Immunoglobulin in an Infant With Kawasaki Disease. ( Inaba, A; Kurano, T; Nakayama, H; Soebijanto, K; Sonoda, M; Tocan, V, 2017)

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-19906 (11.11)18.7374
1990's4 (7.41)18.2507
2000's10 (18.52)29.6817
2010's22 (40.74)24.3611
2020's12 (22.22)2.80

Authors

AuthorsStudies
Lin, SY1
He, L1
Xie, LP1
Wang, Y1
Lin, YX1
Cao, YY1
Yan, WL1
Liu, F1
Huang, GY1
Broderick, C1
Kobayashi, S1
Suto, M1
Ito, S1
Kobayashi, T17
Okada, S1
Hirano, R1
Okazaki-Emi, S1
Fukunaga, S1
Ishikawa, Y1
Furia, FF1
Godfrey, E1
Mwamanenge, N1
Swai, P1
Ueharu, K1
Asano, T1
Fukunaga, R1
Matsui, R1
Yoshida, K1
Miyatake-Sudoh, C1
Abe, M1
Fujita, A1
Ito, Y1
Pilania, RK1
Jindal, AK1
Johnson, N1
Prithvi, A1
Vignesh, P1
Suri, D1
Rawat, A1
Gupta, A1
Singh, S1
Uda, K1
Okita, K1
Soneda, K1
Taniguchi, K1
Horikoshi, Y1
Sakai, H2
Iwashima, S2
Sano, S1
Akiyama, N2
Nagata, E1
Harazaki, M2
Fukuoka, T2
Iio, K1
Sakakibara, H3
Ueno, K2
Nomura, Y3
Morita, Y2
Kawano, Y2
Yoshikane, Y1
Okuma, Y1
Miyamoto, T2
Hashimoto, J1
Fukazawa, R2
Kato, T2
Takeda, A1
Suda, K1
Matsushita, T1
Hiroe, M1
Imanaka-Yoshida, K1
Matsuura, M1
Sugawara, D1
Makita, E1
Hirakubo, Y1
Nonaka, K1
Yamashita, S1
Ichihashi, K1
Morita, A1
Imagawa, K1
Ishiodori, T1
Tagawa, M1
Takada, H1
Nagakura, A1
Morikawa, Y2
Miura, M5
Okubo, Y1
Michihata, N1
Morisaki, N1
Sundel, RP1
Matsui, H1
Fushimi, K1
Yasunaga, H1
Miyata, K1
Kaneko, T1
Matsushima, T1
Misawa, M1
Takahashi, T1
Nakazawa, M1
Tamame, T1
Tsuchihashi, T1
Yamashita, Y1
Obonai, T1
Chiga, M1
Hori, N1
Komiyama, O1
Yamagishi, H1
Burns, JC1
Hoshino, S1
Morikawa, A7
Ikeda, K1
Seki, M2
Shimoyama, S1
Ishii, Y1
Suzuki, T2
Nakajima, K1
Sakamoto, N1
Arakawa, H5
Etoom, Y1
Banihani, R1
Finkelstein, Y1
Goto, M1
Miyagawa, N1
Kikunaga, K1
Hasegawa, Y1
Eguchi, T1
Masuda, K1
Takeda, K1
Sato, T1
Norizuki, M1
Kamata, Y1
Nagatani, K1
Kawarai Lefor, A1
Minota, S1
Nakagama, Y1
Inuzuka, R1
Hayashi, T1
Shindo, T1
Hirata, Y1
Shimizu, N1
Inatomi, J1
Yokoyama, Y1
Namai, Y1
Oda, Y1
Takamizawa, M1
Harita, Y1
Oka, A1
Kimura, M1
Asakura, I1
Kamimaki, T1
Ohkawara, I1
Tsurui, S1
Shimomura, M1
Morishita, H1
Meguro, T1
Seto, S1
Tocan, V1
Inaba, A1
Kurano, T1
Sonoda, M1
Soebijanto, K1
Nakayama, H1
Wardle, AJ1
Connolly, GM1
Seager, MJ1
Tulloh, RM1
Inoue, Y5
Otani, T2
Takeuchi, K3
Saji, T2
Sonobe, T1
Ogawa, S2
Lim, TC1
Yeo, WS1
Loke, KY1
Quek, SC1
Hayashi, M1
Monma, F1
Katagiri, Y1
Kawaguchi, M1
Jibiki, T1
Kato, I1
Shiohama, T1
Abe, K1
Anzai, S1
Takeda, N1
Yamaguchi, KI1
Kanazawa, M2
Kurosaki, T1
Sekine, K1
Mochizuki, H1
Suganuma, E1
Matsuda, S1
Garweg, JG1
Suter, C1
Aebi-Ochsner, C1
Villiger, R1
Son, MB1
Newburger, JW2
Nakamura, T1
Hara, T1
Hamaoka, K2
Fuse, S1
Ichida, F1
Ogawa, C1
Furuno, K1
Tokunaga, H1
Takatsuki, S1
Hara, S1
Okada, Y3
Shinohara, M4
Tomomasa, T3
Onouchi, Z1
Sakata, K1
Ozawa, S1
Shiraishi, I1
Itoi, T1
Kiyosawa, N1
Takeshita, S1
Kawamura, Y1
Nakatani, K1
Tsujimoto, H1
Tokutomi, T1
Higashi, K1
Terai, M1
Hamada, H1
Honda, T1
Kohno, Y1
Yamazaki-Nakashimada, MA1
Ramírez-Vargas, N1
De Rubens-Figueroa, J1
Kato, H2
Ichinose, E1
Sone, K2
Kosuda, T1
Gatenby, PA1
Dale, RC1
Saleem, MA1
Daw, S1
Dillon, MJ1
Koike, S1
Yokoyama, T1
Elamin, AM1
Ikpatt, NW1
Ibia, EO1
Kusakawa, S1
Tatara, K1
Hashimoto, Y1
Yoshinoya, S1
Aikawa, T1
Mitamura, T1
Miyoshi, Y1
Muranaka, M1
Yanase, Y1
Kawasaki, T1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy of Immunoglobulin Plus Prednisolone in Reducing Coronary Artery Lesion in Patients With Kawasaki Disease: A Multicentre Randomised Controlled Trial[NCT04078568]Phase 33,200 participants (Anticipated)Interventional2020-01-15Recruiting
A Randomized Open-label Trial to Evaluate the Efficacy of Immunoglobulin Plus Steroid for Prevention of Coronary Artery Abnormalities in Taiwanese Refractory Kawasaki Disease (RAST Study)[NCT03200561]Phase 3100 participants (Anticipated)Interventional2013-10-17Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for prednisolone and Kawasaki Disease

ArticleYear
Intravenous immunoglobulin for the treatment of Kawasaki disease.
    The Cochrane database of systematic reviews, 2023, 01-25, Volume: 1

    Topics: Acute Coronary Syndrome; Aspirin; Child; Fever; Humans; Immunoglobulins, Intravenous; Inflammation;

2023
Kawasaki disease with dilatation of the common bile duct: A case report and review of literature.
    International journal of rheumatic diseases, 2021, Volume: 24, Issue:10

    Topics: Child, Preschool; Common Bile Duct; Dilatation, Pathologic; Glucocorticoids; Humans; Immunoglobulins

2021
[Prednisolone therapy for Kawasaki disease].
    Nihon rinsho. Japanese journal of clinical medicine, 2014, Volume: 72, Issue:9

    Topics: Acute Disease; Anti-Inflammatory Agents; Humans; Immunoglobulins, Intravenous; Mucocutaneous Lymph N

2014
Corticosteroids for the treatment of Kawasaki disease in children.
    The Cochrane database of systematic reviews, 2017, 01-27, Volume: 1

    Topics: Acute Disease; Adolescent; Adrenal Cortex Hormones; Child; Child, Preschool; Coronary Artery Disease

2017
Vasculitis--diagnosis and treatment.
    Australian and New Zealand journal of medicine, 1999, Volume: 29, Issue:5

    Topics: Adult; Anti-Inflammatory Agents; Antibodies, Antineutrophil Cytoplasmic; Child; Female; Giant Cell A

1999

Trials

7 trials available for prednisolone and Kawasaki Disease

ArticleYear
Effects of immunoglobulin plus prednisolone in reducing coronary artery lesions in patients with Kawasaki disease: study protocol for a phase III multicenter, open-label, blinded-endpoints randomized controlled trial.
    Trials, 2021, Dec-11, Volume: 22, Issue:1

    Topics: Child; Child, Preschool; Clinical Trials, Phase III as Topic; Coronary Vessels; Humans; Immunoglobul

2021
Targeted use of prednisolone with the second IVIG dose for refractory Kawasaki disease.
    Pediatrics international : official journal of the Japan Pediatric Society, 2017, Volume: 59, Issue:4

    Topics: Adolescent; Anti-Inflammatory Agents; Child; Child, Preschool; Drug Administration Schedule; Drug Th

2017
Regulation of oxidative stress in patients with Kawasaki disease.
    Inflammation, 2012, Volume: 35, Issue:3

    Topics: Anti-Inflammatory Agents; Child, Preschool; Combined Modality Therapy; Female; Glutathione; Humans;

2012
Efficacy of immunoglobulin plus prednisolone for prevention of coronary artery abnormalities in severe Kawasaki disease (RAISE study): a randomised, open-label, blinded-endpoints trial.
    Lancet (London, England), 2012, Apr-28, Volume: 379, Issue:9826

    Topics: Anti-Inflammatory Agents; Aspirin; Child, Preschool; Coronary Artery Disease; Coronary Vessel Anomal

2012
Effect of corticosteroids in addition to intravenous gamma globulin therapy on serum cytokine levels in the acute phase of Kawasaki disease in children.
    The Journal of pediatrics, 2003, Volume: 143, Issue:3

    Topics: Acute-Phase Reaction; Anti-Inflammatory Agents; Child; Child, Preschool; Cytokines; Drug Therapy, Co

2003
A multicenter prospective randomized trial of corticosteroids in primary therapy for Kawasaki disease: clinical course and coronary artery outcome.
    The Journal of pediatrics, 2006, Volume: 149, Issue:3

    Topics: Child; Child, Preschool; Coronary Aneurysm; Drug Therapy, Combination; Female; Glucocorticoids; Huma

2006
Impairment of angiogenic activity in the serum from patients with coronary aneurysms due to Kawasaki disease.
    Circulation journal : official journal of the Japanese Circulation Society, 2007, Volume: 71, Issue:7

    Topics: Angiogenesis Inhibitors; Anticoagulants; Aspirin; Cell Proliferation; Cells, Cultured; Child; Child,

2007

Other Studies

42 other studies available for prednisolone and Kawasaki Disease

ArticleYear
Erythema multiforme- and not erythema multiforme-like rashes in Kawasaki disease.
    Pediatrics international : official journal of the Japan Pediatric Society, 2019, Volume: 61, Issue:12

    Topics: Child, Preschool; Chlorpheniramine; Erythema Multiforme; Glucocorticoids; Humans; Immunoglobulins, I

2019
Spectrum of paediatric rheumatic disorders at a tertiary hospital in Tanzania.
    Pediatric rheumatology online journal, 2020, Apr-03, Volume: 18, Issue:1

    Topics: Adolescent; Anemia; Antibodies, Antinuclear; Antirheumatic Agents; Arthralgia; Arthritis, Juvenile;

2020
A Case of Kawasaki Disease with Intussusception.
    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2021, Jan-08, Volume: 87, Issue:6

    Topics: Age Factors; Aspirin; Child, Preschool; Colon; Colonic Diseases; Humans; Immunoglobulins, Intravenou

2021
Macrophage activation syndrome in children with Kawasaki disease: an experience from a tertiary care hospital in northwest India.
    Rheumatology (Oxford, England), 2021, 07-01, Volume: 60, Issue:7

    Topics: Child; Child, Preschool; Coronary Aneurysm; Female; Glucocorticoids; Humans; Immunoglobulins, Intrav

2021
Kawasaki disease following coronavirus disease 2019 with prolonged fecal viral shedding.
    Pediatrics international : official journal of the Japan Pediatric Society, 2021, Volume: 63, Issue:5

    Topics: Anti-Inflammatory Agents; COVID-19; Feces; Humans; Immunoglobulins, Intravenous; Immunologic Factors

2021
Targeted Use of Prednisolone with Intravenous Immunoglobulin for Kawasaki Disease.
    Clinical drug investigation, 2021, Volume: 41, Issue:1

    Topics: Child, Preschool; Cohort Studies; Female; Humans; Immunoglobulins, Intravenous; Infant; Infliximab;

2021
Pneumatosis Intestinalis in a Febrile 11-Month-Old Boy.
    Gastroenterology, 2021, Volume: 161, Issue:5

    Topics: Fever; Gases; Glucocorticoids; Humans; Immunoglobulins, Intravenous; Infant; Male; Mucocutaneous Lym

2021
Prednisolone Suppresses the Extracellular Release of HMGB-1 and Associated Inflammatory Pathways in Kawasaki Disease.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Anti-Inflammatory Agents; Cells, Cultured; Coronary Vessels; Endothelial Cells; HMGB1 Protein; Human

2021
Serum tenascin-C predicts resistance to steroid combination therapy in high-risk Kawasaki disease: a multicenter prospective cohort study.
    Pediatric rheumatology online journal, 2021, Jun-05, Volume: 19, Issue:1

    Topics: Aspirin; Biomarkers; Child; Child, Preschool; Cohort Studies; Drug Combinations; Drug Resistance; Fe

2021
Stratified therapy for Kawasaki disease using a new scoring system to predict the response to a lower dose of intravenous immunoglobulin therapy.
    Cardiology in the young, 2022, Volume: 32, Issue:3

    Topics: Coronary Vessels; Humans; Immunoglobulins, Intravenous; Infant; Mucocutaneous Lymph Node Syndrome; P

2022
Bradycardia Associated with Prednisolone in Children with Severe Kawasaki Disease.
    The Journal of pediatrics, 2017, Volume: 185

    Topics: Bradycardia; Child, Preschool; Cohort Studies; Drug Therapy, Combination; Female; Glucocorticoids; H

2017
Association Between Dose of Glucocorticoids and Coronary Artery Lesions in Kawasaki Disease.
    Arthritis care & research, 2018, Volume: 70, Issue:7

    Topics: Child, Preschool; Coronary Artery Disease; Dose-Response Relationship, Drug; Female; Glucocorticoids

2018
Efficacy and safety of intravenous immunoglobulin plus prednisolone therapy in patients with Kawasaki disease (Post RAISE): a multicentre, prospective cohort study.
    The Lancet. Child & adolescent health, 2018, Volume: 2, Issue:12

    Topics: Aspirin; Child, Preschool; Drug Therapy, Combination; Female; Fever; Glucocorticoids; Humans; Immuno

2018
Kawasaki disease: an essential comparison of coronary artery aneurysm criteria.
    The Lancet. Child & adolescent health, 2018, Volume: 2, Issue:12

    Topics: Anti-Inflammatory Agents; Child; Cohort Studies; Coronary Vessels; Echocardiography; Female; Fever;

2018
Efficacy of intravenous immunoglobulin combined with prednisolone following resistance to initial intravenous immunoglobulin treatment of acute Kawasaki disease.
    The Journal of pediatrics, 2013, Volume: 163, Issue:2

    Topics: Acute Disease; Child, Preschool; Drug Resistance; Drug Therapy, Combination; Female; Glucocorticoids

2013
Critical review of: Efficacy of immunoglobulin plus prednisone for prevention of coronary artery prednisolone for prevention of coronary abnormalities in severe Kawasaki disease (RAISE study): a randomized, open-label, blinded-endpoints trial.
    Journal of population therapeutics and clinical pharmacology = Journal de la therapeutique des populations et de la pharmacologie clinique, 2013, Volume: 20, Issue:2

    Topics: Anti-Inflammatory Agents; Coronary Artery Disease; Coronary Vessel Anomalies; Female; Humans; Immuno

2013
Guidelines for medical treatment of acute Kawasaki disease: report of the Research Committee of the Japanese Society of Pediatric Cardiology and Cardiac Surgery (2012 revised version).
    Pediatrics international : official journal of the Japan Pediatric Society, 2014, Volume: 56, Issue:2

    Topics: Algorithms; Antibodies, Monoclonal; Anticoagulants; Child; Glucocorticoids; Glycoproteins; Humans; I

2014
High incidence of adrenal suppression in children with Kawasaki disease treated with intravenous immunoglobulin plus prednisolone.
    Endocrine journal, 2015, Volume: 62, Issue:2

    Topics: Adrenal Glands; Adrenal Insufficiency; Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Child;

2015
Circulating platelet-neutrophil aggregates play a significant role in Kawasaki disease.
    Circulation journal : official journal of the Japanese Circulation Society, 2015, Volume: 79, Issue:6

    Topics: Aspirin; beta-Thromboglobulin; Blood Platelets; Child, Preschool; Coronary Vessels; Drug Resistance;

2015
Adult Kawasaki-like syndrome with eosinophilia and tenosynovitis in a patient with human immunodeficiency virus infection.
    Rheumatology (Oxford, England), 2015, Volume: 54, Issue:8

    Topics: Adult; Antiviral Agents; Eosinophilia; HIV Infections; Humans; Male; Mucocutaneous Lymph Node Syndro

2015
Fever pattern and C-reactive protein predict response to rescue therapy in Kawasaki disease.
    Pediatrics international : official journal of the Japan Pediatric Society, 2016, Volume: 58, Issue:3

    Topics: C-Reactive Protein; Child, Preschool; Drug Therapy, Combination; Female; Fever; Follow-Up Studies; G

2016
Severe Hemolytic Anemia Following Intravenous Immunoglobulin in an Infant With Kawasaki Disease.
    Journal of pediatric hematology/oncology, 2017, Volume: 39, Issue:2

    Topics: Anemia, Hemolytic, Autoimmune; Autoantibodies; Erythrocyte Transfusion; Hemagglutination Tests; Huma

2017
Risk stratification in the decision to include prednisolone with intravenous immunoglobulin in primary therapy of Kawasaki disease.
    The Pediatric infectious disease journal, 2009, Volume: 28, Issue:6

    Topics: Analysis of Variance; Child, Preschool; Coronary Artery Disease; Female; Humans; Immunoglobulins, In

2009
Bilateral facial nerve palsy in Kawasaki disease.
    Annals of the Academy of Medicine, Singapore, 2009, Volume: 38, Issue:8

    Topics: Anti-Inflammatory Agents; Aspirin; Child; Facial Nerve Diseases; Facial Paralysis; Humans; Immunoglo

2009
Linear immunoglobulin A bullous dermatosis associated with herpes simplex virus infection and Kawasaki disease.
    The Journal of dermatology, 2010, Volume: 37, Issue:3

    Topics: Acyclovir; Aspirin; Basement Membrane; Dapsone; Glycoproteins; Herpes Simplex; Humans; Immunization,

2010
Intravenous immune globulin plus corticosteroids in refractory Kawasaki disease.
    Pediatrics international : official journal of the Japan Pediatric Society, 2011, Volume: 53, Issue:5

    Topics: Acute Disease; Child, Preschool; Drug Administration Schedule; Drug Therapy, Combination; Female; Gl

2011
Macular oedema in Kawasaki syndrome.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2012, Volume: 250, Issue:7

    Topics: Aspirin; Child; Drug Therapy, Combination; Fibrinolytic Agents; Glucocorticoids; Humans; Immunoglobu

2012
Management of Kawasaki disease: corticosteroids revisited.
    Lancet (London, England), 2012, Apr-28, Volume: 379, Issue:9826

    Topics: Anti-Inflammatory Agents; Coronary Artery Disease; Coronary Vessel Anomalies; Female; Humans; Immuno

2012
Long-term changes in coronary artery aneurysms in patients with Kawasaki disease: comparison of therapeutic regimens.
    Circulation journal : official journal of the Japanese Circulation Society, 2005, Volume: 69, Issue:3

    Topics: Acute Disease; Aspirin; Coronary Aneurysm; Coronary Stenosis; gamma-Globulins; Humans; Longitudinal

2005
Standard-dose and short-term corticosteroid therapy in immunoglobulin-resistant Kawasaki disease.
    Clinical pediatrics, 2005, Volume: 44, Issue:5

    Topics: Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resist

2005
Treatment of Kawasaki disease.
    The New England journal of medicine, 2007, Jun-28, Volume: 356, Issue:26

    Topics: Adrenal Cortex Hormones; Coronary Disease; Humans; Mucocutaneous Lymph Node Syndrome; Prednisolone;

2007
Chronic granulomatous disease associated with atypical Kawasaki disease.
    Pediatric cardiology, 2008, Volume: 29, Issue:1

    Topics: Comorbidity; Drug Therapy, Combination; Glucocorticoids; Granulomatous Disease, Chronic; Humans; Imm

2008
[Therapy of Kawasaki disease in the acute phase: steroid and aspirin therapy].
    Nihon rinsho. Japanese journal of clinical medicine, 1983, Volume: 41, Issue:9

    Topics: Acute Disease; Age Factors; Aneurysm; Aspirin; Child, Preschool; Coronary Disease; Humans; Infant; M

1983
Treatment of Kawasaki disease with corticosteroid.
    The Journal of pediatrics, 1996, Volume: 129, Issue:3

    Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Drug Therapy, Combinatio

1996
Treatment of Kawasaki disease: corticosteroids revisited.
    The Journal of pediatrics, 1999, Volume: 135, Issue:4

    Topics: Child; Contraindications; Coronary Aneurysm; Glucocorticoids; Humans; Immunoglobulins, Intravenous;

1999
Corticosteroids in the treatment of the acute phase of Kawasaki disease.
    The Journal of pediatrics, 1999, Volume: 135, Issue:4

    Topics: Acute Disease; Aspirin; Child, Preschool; Coronary Aneurysm; Dipyridamole; Drug Therapy, Combination

1999
Treatment of severe complicated Kawasaki disease with oral prednisolone and aspirin.
    The Journal of pediatrics, 2000, Volume: 137, Issue:5

    Topics: Anti-Inflammatory Agents; Aspirin; Child; Child, Preschool; Drug Therapy, Combination; Glucocorticoi

2000
Kawasaki disease: effect of treatment on coronary artery involvement.
    Pediatrics, 1979, Volume: 63, Issue:2

    Topics: Aspirin; Cephalexin; Child, Preschool; Coronary Angiography; Coronary Circulation; Coronary Disease;

1979
Kawasaki disease in two African siblings.
    Tropical doctor, 1979, Volume: 9, Issue:4

    Topics: Africa; Child; Female; Humans; Hydrocortisone; Infant; Lymphatic Diseases; Male; Mucocutaneous Lymph

1979
Mucocutaneous lymph node syndrome in Calabar--a case report.
    East African medical journal, 1989, Volume: 66, Issue:11

    Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Child, Preschool; Female

1989
Efficacies and risks of aspirin in the treatment of the Kawasaki disease.
    Progress in clinical and biological research, 1987, Volume: 250

    Topics: Aspirin; Child; Child, Preschool; Coronary Aneurysm; Humans; Immunization, Passive; Mucocutaneous Ly

1987
Enhanced endothelial cell proliferation in acute Kawasaki disease (muco-cutaneous lymph node syndrome).
    Pediatric research, 1986, Volume: 20, Issue:10

    Topics: Antigen-Antibody Complex; Cell Division; Cells, Cultured; Chemical Fractionation; Child; Child, Pres

1986