prednisolone and Hepatitis studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Research Excerpts

Excerpt	Relevance	Reference
"In most patients with autoimmune hepatitis, remission can be maintained with prednisolone, usually in combination with azathioprine, but the majority of patients have a relapse when treatment is stopped and therefore require long-term therapy."	9.08	Azathioprine for long-term maintenance of remission in autoimmune hepatitis. ( Johnson, PJ; McFarlane, IG; Williams, R, 1995)
"A long-term follow-up of at least 10 years or until death of 44 patients taking part in a controlled prospective trial of prednisolone therapy in hepatitis B antigen negative chronic active hepatitis (lupoid hepatitis) has been performed at the Royal Free Hospital, London."	9.05	Late results of the Royal Free Hospital prospective controlled trial of prednisolone therapy in hepatitis B surface antigen negative chronic active hepatitis. ( Jain, S; Kirk, AP; Pocock, S; Sherlock, S; Thomas, HC, 1980)
"To study the efficacy of corticosteroids in chronic active hepatitis (CAH) positive for hepatitis B surface antigen (HBsAg), we pair-randomized 51 patients to receive either 15 to 20 mg of prednisolone per day or a placebo."	9.05	Deleterious effect of prednisolone in HBsAg-positive chronic active hepatitis. ( Lai, CL; Lam, KC; Trepo, C; Wu, PC, 1981)
"A total of 54 patients hospitalized for chronic active hepatitis were randomly treated, 29 with prednisolone (maintenance dose 15 mg/day) and 25 with depot synthetic corticotrophin (maintenance dose 1 mg/week, i."	9.04	Treatment of chronic active hepatitis with either prednisolone or corticotrophin: a controlled trial. ( Galanti, B; Giusti, G; Lucchelli, PE; Manzillo, G; Piccinino, F; Ruggiero, G; Sagnelli, E; Utili, R, 1977)
"1 The plasma availability of prednisolone after oral doses of prednisolone and its precursor, prednisone, were compared in ten normal controls and twenty-five patients with chronic active hepatitis by estimation of the area under the plasma concentration--time curve for the drug (AUC)."	9.04	Prednisone or prednisolone for the treatment of chronic active hepatitis? A comparison of plasma availability. ( Chakraborty, J; Davis, M; English, J; Ideo, G; Marks, V; Tempini, S; Williams, R, 1978)
"To our knowledge, this is the first reported case of drug rash with eosinophilia and systemic symptoms syndrome induced by bupropion therapy."	7.72	Drug-induced rash with eosinophilia and systemic symptoms syndrome with bupropion administration. ( Bagshaw, SM; Bowen, TJ; Cload, B; Gilmour, J; Leung, ST, 2003)
"We report a case of primary biliary cirrhosis-autoimmune hepatitis overlap syndrome treated with cyclosporine A."	7.69	Primary biliary cirrhosis-autoimmune hepatitis overlap syndrome. Corticoresistance and effective treatment by cyclosporine A. ( Degott, C; Duclos-Vallée, JC; Erlinger, S; Ganne-Carrié, N; Hadengue, A; Robin, E, 1995)
"A 33-year-old woman with autoimmune hepatitis developed resistance to prednisolone-azathioprine treatment."	7.69	Treatment of corticosteroid-azathioprine resistant autoimmune hepatitis with cyclosporin A. ( Senturk, H, 1995)
"Forty five patients were examined in order to evaluate the usefulness of glucagon and insulin as a therapy of fulminant hepatitis."	7.67	Clinical evaluation of glucagon and insulin in therapy of fulminant hepatitis. ( Hanta, T; Matsuda, S; Okita, K; Sanuki, K; Takemoto, T; Yasunaga, M, 1987)
"Follow-up studies were conducted in the patients with chronic active hepatitis treated 10 years ago with tiopronin (TP) or corticosteroids (CS)."	7.66	Follow-up study in chronic active hepatitis after therapies with immunosuppressive drugs and tiopronin. ( Nagashima, H; Tsuji, T, 1981)
"The metabolism of unconjugated bilirubin from the plasma was studied in 17 patients with chronic hepatitis and 7 normal subjects following a single injection of bilirubin of 2 mg per kg body weight."	7.65	Effect of corticosteroid treatment on bilirubin metabolism in chronic aggressive hepatitis. ( Hirayama, C; Irisa, T; Kawasaki, H; Ogata, T, 1977)
"A description is given of four patients with active chronic hepatitis, all of whom were treated with prednisolone and cyclophosphamide."	7.65	Remission of active chronic hepatitis after treatment with cyclophosphamide and prednisolone. Report of four cases. ( Jennings, RC; Pengelly, CD, 1975)
"To determine the efficacy of amoxicillin-clavulanate, compared with placebo, on mortality in patients hospitalized with severe alcohol-related hepatitis and treated with prednisolone."	5.69	Effect of Prophylactic Antibiotics on Mortality in Severe Alcohol-Related Hepatitis: A Randomized Clinical Trial. ( Anty, R; Bernard-Chabert, B; Bureau, C; Carbonell, N; Dao, T; Duhamel, A; Hilleret, MN; Labreuche, J; Louvet, A; Mathurin, P; Minello, A; Moirand, R; Nahon, P; Nguyen-Khac, E; Oberti, F; Pageaux, GP; Paupard, T; Potey, C; Thévenot, T; Wartel, F, 2023)
" The results suggest that JKB-122 as monotherapy or in combination with prednisolone may offer a viable approach to the treatment of AIH."	5.46	JKB-122 is effective, alone or in combination with prednisolone in Con A-induced hepatitis. ( Chiu, PJS; Hsu, MC; Hu, NY; Liu, SH; Shih, YC; Wang, CW; Wu, ESC, 2017)
"Treatment with ursodeoxycholic acid (UDCA), subsequently added to the immunosuppressive therapy, apparently normalized the levels of biliary tract enzyme and total bilirubin."	5.31	Hepatic graft-versus-host disease resembling acute hepatitis: additional treatment with ursodeoxycholic acid. ( Chiba, T; Fukai, K; Imazeki, F; Kanda, T; Nishimura, M; Saisho, H; Saito, Y; Yokosuka, O, 2002)
"In most patients with autoimmune hepatitis, remission can be maintained with prednisolone, usually in combination with azathioprine, but the majority of patients have a relapse when treatment is stopped and therefore require long-term therapy."	5.08	Azathioprine for long-term maintenance of remission in autoimmune hepatitis. ( Johnson, PJ; McFarlane, IG; Williams, R, 1995)
"Immunosuppressive treatment with prednisolone and azathioprine was administered to a small group of nine patients in the early stage of chronic active or inactive hepatitis about six months after onset of the disease."	5.05	[Immunosuppressive treatment of the early stages of active or inactive chronic hepatitis: results of a pilot study (author's transl)]. ( Ranft, U; Schmidt, FW; Vido, I, 1980)
"A long-term follow-up of at least 10 years or until death of 44 patients taking part in a controlled prospective trial of prednisolone therapy in hepatitis B antigen negative chronic active hepatitis (lupoid hepatitis) has been performed at the Royal Free Hospital, London."	5.05	Late results of the Royal Free Hospital prospective controlled trial of prednisolone therapy in hepatitis B surface antigen negative chronic active hepatitis. ( Jain, S; Kirk, AP; Pocock, S; Sherlock, S; Thomas, HC, 1980)
"To study the efficacy of corticosteroids in chronic active hepatitis (CAH) positive for hepatitis B surface antigen (HBsAg), we pair-randomized 51 patients to receive either 15 to 20 mg of prednisolone per day or a placebo."	5.05	Deleterious effect of prednisolone in HBsAg-positive chronic active hepatitis. ( Lai, CL; Lam, KC; Trepo, C; Wu, PC, 1981)
"A total of 54 patients hospitalized for chronic active hepatitis were randomly treated, 29 with prednisolone (maintenance dose 15 mg/day) and 25 with depot synthetic corticotrophin (maintenance dose 1 mg/week, i."	5.04	Treatment of chronic active hepatitis with either prednisolone or corticotrophin: a controlled trial. ( Galanti, B; Giusti, G; Lucchelli, PE; Manzillo, G; Piccinino, F; Ruggiero, G; Sagnelli, E; Utili, R, 1977)
"In a prospective, randomized, double-blind study of prednisolone therapy of acute alcoholic hepatitis, 39% of the total group of 28 patients died."	5.04	Adrenocorticosteroid therapy in alcoholic hepatitis. A prospective, double-blind randomized study. ( Blitzer, BL; Conn, HO; Fessel, JM; Joshi, PH; Mutchnick, MG; Phillips, MM, 1977)
"The effect of prednisone (15 mg/day) or azathioprine (2 mg/kg daily) or a combination of prednisone (10 mg/day) and azathioprine (2 mg/kg daily) was assessed in a controlled multi-centre trial of chronic-active hepatitis."	5.04	[Immunosuppressive treatment of HBs-antigen positive and negative chronic-active hepatitis (author's transl)]. ( Meyer, KH, 1978)
"1 The plasma availability of prednisolone after oral doses of prednisolone and its precursor, prednisone, were compared in ten normal controls and twenty-five patients with chronic active hepatitis by estimation of the area under the plasma concentration--time curve for the drug (AUC)."	5.04	Prednisone or prednisolone for the treatment of chronic active hepatitis? A comparison of plasma availability. ( Chakraborty, J; Davis, M; English, J; Ideo, G; Marks, V; Tempini, S; Williams, R, 1978)
"Immunosuppressive treatment with prednisolone and/or azathioprine has been assessed in three chronic liver diseases with immunological features, namely chronic active hepatitis, cryptogenic cirrhosis and primary biliary cirrhosis."	5.04	Immunosuppressive therapy in chronic liver disease. ( Sherlock, S, 1978)
"MODE OF ACTION OF URSODEOXYCHOLIC ACID: In cholestasis, the impaired biliary secretion of toxic bile acids causes their accumulation in the liver and a subsequent hepatic failure."	4.81	[Treatment of cholestatic liver diseases]. ( Gatzen, M; Pausch, J, 2002)
" Although he was previously treated with prednisolone (1 mg/kg/day) for immune-related adverse event (irAE) hepatitis by a previous doctor, he still had worsening liver function and was transferred to our hospital."	4.31	Immune-related adverse events in hepatitis treated with thiopurine-based immunosuppressants: A case report. ( Hamaguchi, M; Horie, M; Isobe, T; Kawakado, K; Nagase, M; Nakashima, K; Okimoto, T; Tobita, H; Tsubata, Y; Yoshihara, K, 2023)
"We report a rare case of acute Q fever granulomatous hepatitis remained pyrexia despite several antibiotic therapy and 6-day course of oral prednisolone."	3.76	Circulating cytokines and procalcitonin in acute Q fever granulomatous hepatitis with poor response to antibiotic and short-course steroid therapy: a case report. ( Chang, LL; Chen, YH; Lai, CH; Lin, HH; Lin, JN, 2010)
"To our knowledge, this is the first reported case of drug rash with eosinophilia and systemic symptoms syndrome induced by bupropion therapy."	3.72	Drug-induced rash with eosinophilia and systemic symptoms syndrome with bupropion administration. ( Bagshaw, SM; Bowen, TJ; Cload, B; Gilmour, J; Leung, ST, 2003)
"A 33-year-old woman with autoimmune hepatitis developed resistance to prednisolone-azathioprine treatment."	3.69	Treatment of corticosteroid-azathioprine resistant autoimmune hepatitis with cyclosporin A. ( Senturk, H, 1995)
" The autoimmune hepatitis was treated with prednisolone (initially 60 mg daily, then reduced to 10 mg daily) and azathioprine (initially 100 mg daily, reduced to 50 mg daily)."	3.69	[Autoimmune hepatitis, autoimmune gastritis, hypergastrinemia and stomach carcinoid]. ( Ormann, W, 1995)
"We report a case of primary biliary cirrhosis-autoimmune hepatitis overlap syndrome treated with cyclosporine A."	3.69	Primary biliary cirrhosis-autoimmune hepatitis overlap syndrome. Corticoresistance and effective treatment by cyclosporine A. ( Degott, C; Duclos-Vallée, JC; Erlinger, S; Ganne-Carrié, N; Hadengue, A; Robin, E, 1995)
"Forty five patients were examined in order to evaluate the usefulness of glucagon and insulin as a therapy of fulminant hepatitis."	3.67	Clinical evaluation of glucagon and insulin in therapy of fulminant hepatitis. ( Hanta, T; Matsuda, S; Okita, K; Sanuki, K; Takemoto, T; Yasunaga, M, 1987)
"This report deals with a 25-year-old man with chronic active hepatitis and cirrhosis who developed the rare complication of pyoderma gangrenosum which improved rapidly following the commencement of prednisolone."	3.66	The association of chronic active hepatitis with pyoderma gangrenosum. ( Fraser, KJ; Marshall, AW; Slonim, JM; Smallwood, RA, 1978)
"Follow-up studies were conducted in the patients with chronic active hepatitis treated 10 years ago with tiopronin (TP) or corticosteroids (CS)."	3.66	Follow-up study in chronic active hepatitis after therapies with immunosuppressive drugs and tiopronin. ( Nagashima, H; Tsuji, T, 1981)
"Early-stage chronic active hepatitis treated with prednisolone and azathioprine has a good prognosis."	3.66	[Immunosuppressive treatment of chronic active hepatitis (author's transl)]. ( Ranft, U; Schmidt, FW; Vido, I, 1980)
"The metabolism of unconjugated bilirubin from the plasma was studied in 17 patients with chronic hepatitis and 7 normal subjects following a single injection of bilirubin of 2 mg per kg body weight."	3.65	Effect of corticosteroid treatment on bilirubin metabolism in chronic aggressive hepatitis. ( Hirayama, C; Irisa, T; Kawasaki, H; Ogata, T, 1977)
"The sera of 24 patients with chronic aggressive hepatitis receiving combined immunosuppressive therapy were studied for the concentrations of the carbohydrate components of glycoproteins and the IgG, IgA, IgM, alpha-2-macroglobulin, coeruloplasmin, beta-1-C-globulin and transferrin levels over a period of 2 years."	3.65	Effect of immunosuppressive therapy on the serum glycoprotein levels in chronic aggressive hepatitis. ( Fehér, J; Jakab, L; Papp, G; Süle, I; Szilvási, I; Tenczer, J, 1976)
"A description is given of four patients with active chronic hepatitis, all of whom were treated with prednisolone and cyclophosphamide."	3.65	Remission of active chronic hepatitis after treatment with cyclophosphamide and prednisolone. Report of four cases. ( Jennings, RC; Pengelly, CD, 1975)
"In human patients with liver cirrhosis, portal vein thrombosis (PVT) is a common complication."	1.62	Long-term follow-up of portal vein thrombosis in an American Cocker Spaniel with lobular dissecting hepatitis: a case report. ( Ishikawa, C; Kagawa, Y; Nakayama, T; Sakai, M; Sakamoto, Y; Sato, K, 2021)
"Liver fibrosis was not coarse, but delicate with severe activity in most patients showing chronic hepatitis defined by our strict criteria."	1.48	Long-term observation of acute-onset autoimmune hepatitis presenting clinically and radiologically as acute hepatitis. ( Fujiwara, K; Fukuda, Y; Kato, N; Nakano, M; Saito, M; Seza, K; Yasui, S; Yokosuka, O, 2018)
" The results suggest that JKB-122 as monotherapy or in combination with prednisolone may offer a viable approach to the treatment of AIH."	1.46	JKB-122 is effective, alone or in combination with prednisolone in Con A-induced hepatitis. ( Chiu, PJS; Hsu, MC; Hu, NY; Liu, SH; Shih, YC; Wang, CW; Wu, ESC, 2017)
"Imatinib mesylate has dramatically improved the outcome of children with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph* ALL) and is now included as first-line therapy."	1.42	Imatinib-induced Severe Hepatitis in a 9-Year-old Girl With Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia. ( Fukushima, H; Fukushima, T; Kobayashi, C; Nanmoku, T; Sakai, A; Satomi, K; Sumazaki, R; Suzuki, R; Tagawa, M, 2015)
"Hepatic plasma cell infiltration of multiple myeloma can, in rare cases, manifest as acute cholestatic hepatitis, which may respond to treatment with corticosteroids."	1.33	Severe acute cholestatic hepatitis by infiltration of monoclonal plasma cells in multiple myeloma. ( Andus, T; Barth, C; Bosse, A, 2005)
"Although pulmonary nocardiosis is difficult to diagnose, prompt use of the gram-staining procedure and appropriate treatment appeared to improve survival."	1.32	[Pulmonary infection with Nocardia species: a report of 10 cases]. ( Takiguchi, Y; Uruma, R, 2004)
"Treatment with prednisolone (2 mg/kg/day) for 14 days resulted in dramatic improvement of the thrombocytopenia."	1.32	Neonatal lupus erythematosus with cholestatic hepatitis. ( Chuo, HT; Huang, LH; Lee, HC; Lin, SC; Shyur, SD; Wu, JY, 2004)
"Treatment with ursodeoxycholic acid (UDCA), subsequently added to the immunosuppressive therapy, apparently normalized the levels of biliary tract enzyme and total bilirubin."	1.31	Hepatic graft-versus-host disease resembling acute hepatitis: additional treatment with ursodeoxycholic acid. ( Chiba, T; Fukai, K; Imazeki, F; Kanda, T; Nishimura, M; Saisho, H; Saito, Y; Yokosuka, O, 2002)
"In addition, primary hypothyroidism due to Hashimoto's thyroiditis and secondary hypocortisolism due to isolated ACTH deficiency were revealed by endocrinological examination."	1.30	Simultaneously found transient hypothyroidism due to Hashimoto's thyroiditis, autoimmune hepatitis and isolated ACTH deficiency after cessation of glucocorticoid administration. ( Ieki, Y; Kobayashi, K; Nagai, Y; Ohsawa, K, 1997)
"A 4 year-old boy presented with severe acute hepatic failure (AHF) without hypergammaglobulinemia, revealing AIH."	1.30	[Autoimmune hepatitis treated with cyclosporin revealed by acute hepatocellular failure]. ( Farriaux, JP; Gottrand, F; Launay, V; Masy, E; Michaud, L; Turck, D, 1997)
"Polyarthralgia, hoarseness and the abnormalities of the transaminase levels improved rapidly."	1.29	[Undifferentiated connective tissue syndromes (UCTS) accompanied by laryngeal involvement and autoimmune hepatitis]. ( Kamoshida, T; Nishinarita, M; Ohta, S; Oka, Y; Takahashi, A; Uesato, M, 1995)
"Chronic persistent hepatitis is a benign condition and special treatment is not necessary."	1.26	Treatment of chronic hepatitis. ( Sherlock, S, 1980)
"15 patients with primary biliary cirrhosis (PBC) and 109 patients with chronic aggressive hepatitis (CAH) have been followed."	1.26	[Combined form of chronic aggressive hepatitis primary biliary cirrhosis]. ( Cueni, B; Schmid, M; Zimmermann, K, 1977)
"Later, primary hepatocellular carcinoma assumes increasing importance."	1.25	Viral hepatitis and cirrhosis. ( Sherlock, S, 1975)
"Prednisolone therapy was associated with significant increases in the plasma concentration and synthetic rate of albumin but changes in the intravascular albumin pools were not significant."	1.25	Augmentation of albumin but not fibrinogen synthesis by corticosteroids in patients with hepatocellular disease. ( Cain, GD; Jones, EA; Mayer, G, 1970)

Timeframe	Studies, this research(%)	All Research%
pre-1990	196 (79.35)	18.7374
1990's	26 (10.53)	18.2507
2000's	12 (4.86)	29.6817
2010's	8 (3.24)	24.3611
2020's	5 (2.02)	2.80

Article	Year
Immunoglobulin G4-related Liver Disease Overlapping with Non-alcoholic Steatohepatitis That Was Diagnosed Simultaneously with Autoimmune Pancreatitis: A Case Report and Review of the Literature. Internal medicine (Tokyo, Japan), 2019, Dec-15, Volume: 58, Issue:24 Topics: Adult; Aged; Antibodies, Antinuclear; Autoimmune Pancreatitis; Biopsy; Blood Chemical Analysis; Fema	2019
Bacillus Calmette-Guérin-induced granulomatous hepatitis in a patient with a superficial bladder carcinoma. European journal of gastroenterology & hepatology, 2004, Volume: 16, Issue:10 Topics: Adjuvants, Immunologic; Administration, Intravesical; Aged; Antitubercular Agents; BCG Vaccine; Biop	2004
[Therapy of chronic hepatitis other than interferon therapy]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1994, Feb-10, Volume: 83, Issue:2 Topics: Antiviral Agents; Chronic Disease; Drugs, Chinese Herbal; Glycyrrhetinic Acid; Glycyrrhizic Acid; He	1994
[Therapy of autoimmune hepatitis]. Deutsche medizinische Wochenschrift (1946), 1996, Dec-06, Volume: 121, Issue:49 Topics: Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents; Autoimmune Diseases; Azathioprine; Budeson	1996
[Treatment of cholestatic liver diseases]. Medizinische Klinik (Munich, Germany : 1983), 2002, Mar-15, Volume: 97, Issue:3 Topics: Adult; Age Factors; Anti-Inflammatory Agents; Azathioprine; Bile; Child; Cholagogues and Choleretics	2002
[Corticosteroids in gastroenterology]. Nederlands tijdschrift voor geneeskunde, 1978, Mar-25, Volume: 122, Issue:12 Topics: Adrenal Cortex Hormones; Burns, Chemical; Celiac Disease; Chronic Disease; Colitis, Ulcerative; Croh	1978
[Chronic hepatitis: when and how to treat? (author's transl)]. Therapeutische Umschau. Revue therapeutique, 1978, Volume: 35, Issue:9 Topics: Adrenal Cortex Hormones; Azathioprine; Chronic Disease; Hepatitis; Hepatitis B Antigens; Humans; Imm	1978
[Current aspects of the therapy of chronic hepatitis (a review of the literature)]. Voprosy okhrany materinstva i detstva, 1979, Volume: 24, Issue:11 Topics: Adjuvants, Immunologic; Adrenal Cortex Hormones; Adult; Azathioprine; BCG Vaccine; Child; Chronic Di	1979
Corticosteroids in liver disease: possible mechanisms of action, pharmacology, and rational use. Gut, 1979, Volume: 20, Issue:12 Topics: Adrenal Cortex Hormones; Chronic Disease; Hepatitis; Humans; Immunity, Cellular; Liver Diseases; Liv	1979
[Chronic hepatitis]. Recenti progressi in medicina, 1976, Volume: 60, Issue:5 Topics: Azathioprine; Hepatitis; Hepatitis B; Humans; Liver Cirrhosis; Prednisolone; Prednisone; Prognosis	1976
[Problem of chronic hepatitis (classification, pathogenesis and treatment]. Klinicheskaia meditsina, 1991, Volume: 69, Issue:6 Topics: Autoimmune Diseases; Azathioprine; Chronic Disease; Hepatitis; Hepatitis B; Hepatitis B Antibodies;	1991
Observations on plasma cortisol and ACTH in chronic liver disease and after chronocorticosteroid treatment. Chronobiologia, 1974, Volume: 1 Suppl 1 Topics: Adrenal Glands; Adrenocorticotropic Hormone; Chronic Disease; Circadian Rhythm; Cortisone; Dexametha	1974
Immunosuppressive therapy. 1. The New England journal of medicine, 1972, Aug-03, Volume: 287, Issue:5 Topics: Alkylating Agents; Anemia, Hemolytic, Autoimmune; Antibodies; Antimetabolites; Arthritis, Rheumatoid	1972
Advances in gastroenterology. The Practitioner, 1972, Volume: 209, Issue:252 Topics: Adrenal Cortex Hormones; Azathioprine; Chronic Disease; Colitis, Ulcerative; Diet; Disaccharides; Du	1972
Chronic active liver disease reexamined: prognosis hopeful. Gastroenterology, 1974, Volume: 66, Issue:3 Topics: Adrenal Cortex Hormones; Adult; Antibodies; Autoimmune Diseases; Azathioprine; Child, Preschool; Chr	1974
Treatment of liver disease with corticosteroids. The Medical clinics of North America, 1973, Volume: 57, Issue:5 Topics: Adrenal Cortex Hormones; Alcoholism; Azathioprine; Chemical and Drug Induced Liver Injury; Glucocort	1973
[Corticosteroid therapy in modern medicine (on the 25th anniversary of the first application of cortisone)]. Sovetskaia meditsina, 1974, Volume: 0, Issue:7 Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Asthma; Collagen Diseases; Cortisone; Glucocorticoid	1974
Chronic hepatitis. Gut, 1974, Volume: 15, Issue:7 Topics: Adult; Animals; Autoimmune Diseases; Azathioprine; Chemical and Drug Induced Liver Injury; Child; Ch	1974
[Glucocorticoids and immunosuppressive agents in liver diseases]. Revista espanola de las enfermedades del aparato digestivo, 1970, Dec-01, Volume: 32, Issue:7 Topics: Acute Disease; Glucocorticoids; Hepatitis; Humans; Immunosuppressive Agents; Liver; Liver Cirrhosis;	1970

Article	Year
Effect of Prophylactic Antibiotics on Mortality in Severe Alcohol-Related Hepatitis: A Randomized Clinical Trial. JAMA, 2023, 05-09, Volume: 329, Issue:18 Topics: Adult; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Anti-Inflammatory Agent	2023
Is chronic active hepatitis curable? Lancet (London, England), 1982, Apr-17, Volume: 1, Issue:8277 Topics: Azathioprine; Chronic Disease; Clinical Trials as Topic; Drug Therapy, Combination; Hepatitis; Human	1982
Late results of the Royal Free Hospital prospective controlled trial of prednisolone therapy in hepatitis B surface antigen negative chronic active hepatitis. Gut, 1980, Volume: 21, Issue:1 Topics: Adolescent; Adult; Aged; Aspartate Aminotransferases; Child; Child, Preschool; Chronic Disease; Clin	1980
Deleterious effect of prednisolone in HBsAg-positive chronic active hepatitis. The New England journal of medicine, 1981, Feb-12, Volume: 304, Issue:7 Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Bilirubin; Chronic Disease; Clinical Trial	1981
[Immunosuppressive treatment of the early stages of active or inactive chronic hepatitis: results of a pilot study (author's transl)]. Deutsche medizinische Wochenschrift (1946), 1980, Oct-10, Volume: 105, Issue:41 Topics: Azathioprine; Chronic Disease; Hepatitis; Humans; Prednisolone; Time Factors	1980
Azathioprine for long-term maintenance of remission in autoimmune hepatitis. The New England journal of medicine, 1995, Oct-12, Volume: 333, Issue:15 Topics: Adolescent; Adult; Aged; Arthralgia; Autoimmune Diseases; Azathioprine; Disease-Free Survival; Femal	1995
Metabolism of a prednisolone compound in human under normal and pathological conditions. Arzneimittel-Forschung, 1975, Volume: 25, Issue:8 Topics: Adolescent; Adult; Aged; Biotransformation; Clinical Trials as Topic; Female; Glucocorticoids; Half-	1975
Treatment of chronic active hepatitis with either prednisolone or corticotrophin: a controlled trial. Acta hepato-gastroenterologica, 1977, Volume: 24, Issue:3 Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Child; Chronic Disease; Female; gamma-Globulins; Hep	1977
Adrenocorticosteroid therapy in alcoholic hepatitis. A prospective, double-blind randomized study. The American journal of digestive diseases, 1977, Volume: 22, Issue:6 Topics: Acute Disease; Adrenal Cortex Hormones; Alcoholism; Alkaline Phosphatase; Aspartate Aminotransferase	1977
Treatment of chronic active hepatitis. An analysis of three controlled trials. Gastroenterology, 1977, Volume: 73, Issue:6 Topics: Azathioprine; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Drug	1977
[Clinical evaluation of the use of a chronopluricorticoid in the therapy of active chronic hepatitis]. La Clinica terapeutica, 1979, Oct-15, Volume: 91, Issue:1 Topics: Adrenal Cortex Hormones; Adult; Aged; Clinical Trials as Topic; Cortisone; Drug Combinations; Endocr	1979
[Immunosuppressive treatment of HBs-antigen positive and negative chronic-active hepatitis (author's transl)]. Deutsche medizinische Wochenschrift (1946), 1978, May-26, Volume: 103, Issue:21 Topics: Adult; Age Factors; Aged; Alanine Transaminase; Autoantibodies; Azathioprine; Chronic Disease; Femal	1978
Prednisone or prednisolone for the treatment of chronic active hepatitis? A comparison of plasma availability. British journal of clinical pharmacology, 1978, Volume: 5, Issue:6 Topics: Adult; Biological Availability; Chronic Disease; Female; Half-Life; Hepatitis; Humans; Male; Prednis	1978
Immunosuppressive therapy in chronic liver disease. Minerva medica, 1978, Aug-18, Volume: 69, Issue:38 Topics: Azathioprine; Chronic Disease; Drug Therapy, Combination; Hepatitis; Hepatitis B; Hepatitis B Surfac	1978
Microcrystalline hydroxyapatite compound in prevention of bone loss in corticosteroid-treated patients with chronic active hepatitis. Postgraduate medical journal, 1985, Volume: 61, Issue:719 Topics: Adult; Aged; Bone and Bones; Bone Resorption; Chronic Disease; Clinical Trials as Topic; Durapatite;	1985
[Prognostic experiences in the long-term differential therapy of chronic aggressive hepatitides]. Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1974, Volume: 34, Issue:5-6 Topics: Adolescent; Adult; Alkaline Phosphatase; Child; Chronic Disease; Female; Hepatitis; Humans; Iron; Lo	1974
Immunosuppressive therapy. 1. The New England journal of medicine, 1972, Aug-03, Volume: 287, Issue:5 Topics: Alkylating Agents; Anemia, Hemolytic, Autoimmune; Antibodies; Antimetabolites; Arthritis, Rheumatoid	1972
Alcoholic hepatitis. The New England journal of medicine, 1971, Jun-17, Volume: 284, Issue:24 Topics: Age Factors; Alcoholism; Clinical Trials as Topic; Glucocorticoids; Hepatitis; Humans; Prednisolone	1971
Controlled prospective trial of corticosteroid therapy in active chronic hepatitis. The Quarterly journal of medicine, 1971, Volume: 40, Issue:158 Topics: Adolescent; Adult; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Blood Sedimentation	1971
Effect of corticosteroid therapy on bromsulphthalein excretion in active chronic hepatitis. Gut, 1968, Volume: 9, Issue:3 Topics: Adolescent; Adult; Aspartate Aminotransferases; Bilirubin; Child; Chronic Disease; Female; Hepatitis	1968

prednisolone and Hepatitis

Research Excerpts

Research

Studies (247)

Authors

Reviews

Trials

Other Studies

Authors	Studies
Sakamoto, Y	1
Sato, K	1
Ishikawa, C	1
Kagawa, Y	1
Nakayama, T	1
Sakai, M	1
Kawakado, K	1
Nakashima, K	1
Tobita, H	1
Nagase, M	1
Yoshihara, K	1
Horie, M	1
Hamaguchi, M	1
Okimoto, T	1
Tsubata, Y	1
Isobe, T	1
Louvet, A	1
Labreuche, J	1
Dao, T	1
Thévenot, T	1
Oberti, F	1
Bureau, C	1
Paupard, T	1
Nguyen-Khac, E	1
Minello, A	1
Bernard-Chabert, B	1
Anty, R	1
Wartel, F	1
Carbonell, N	1
Pageaux, GP	1
Hilleret, MN	1
Moirand, R	1
Nahon, P	1
Potey, C	1
Duhamel, A	1
Mathurin, P	1
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Munetsugu, T	1
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Fujimoto, N	1
Satoh, T	1
Kanchongkittiphon, W	1
Kittinon, K	1
Wanitchakorn, A	1
Benjaponpitak, S	1
Manuyakorn, W	1
Hsu, MC	1
Liu, SH	1
Wang, CW	1
Hu, NY	1
Wu, ESC	1
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Chiu, PJS	1
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Saito, M	2
Yasui, S	1
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Yokosuka, O	2
Kato, N	1
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Kumazawa, H	1
Isono, Y	1
Tanaka, H	1
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Saito, T	1
Mukai, K	1
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Murata, T	1
Matsumoto, K	1
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Kuniyoshi, N	1
Tsunashima, H	1
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Miyakawa, H	1
Aoyama, T	1
Matsumoto, T	1
Uchiyama, A	1
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Suzuki, R	1
Kobayashi, C	1
Sakai, A	1
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Satomi, K	1
Nanmoku, T	1
Sumazaki, R	2
Fukushima, T	1
Lai, CH	1
Lin, JN	1
Chang, LL	1
Chen, YH	1
Lin, HH	1
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Hsu, YH	1
Hu, CT	1
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Ganschow, R	1
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Saito, Y	1
Bagshaw, SM	1
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Leung, ST	1
Bowen, TJ	1
WISSMER, B	2
TILLING, W	1
SIEGENTHALER, W	1
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MAINGUET, P	2
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RISSEL, E	1
SCHNACK, H	1
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WILLIAMS, R	5
BILLING, BH	2
MATVEEV, AA	2
GROS, H	1
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KAMAT, GR	1
NANAVATI, JM	1
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GIKALOV, GS	1
KAZAKOV, NF	1
SIEDE, W	1
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KORANYI, G	1
SCHMIDT, E	1
SCHMIDT, FW	3
IAKOVLEV, AF	1
SZECSEY, G	2
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PORGANYI, M	2
LEVINA, LD	1
STEINBECK, AW	1
UGARTE, G	1
PINO, ME	1
VALENZUELA, J	1
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MACKAY, IR	5
WEIDEN, S	1
UNGAR, B	1
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CHISTOVA, LV	3
SHELIAPINA, VV	2
SHERLOCK, S	11
HALMOS, T	1
LOCZKA, B	1
SALAMON, F	1
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TIAPINA, LA	1
KUDRIASHOVA, ZS	1
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HOFF, WV	1
MUENNICH, D	1
SZABADFALVY, A	1
LINDBLAD, G	1
MEHROTRA, MP	1
MALVIYA, US	1
NIGAM, DK	1
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PESIK, AN	1
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KURISU, A	1
SUGIYAMA, H	1
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POPESCU, IG	1
ZAMFIRESCU-GHEORGHIU, M	1
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