prednisolone has been researched along with Hemolysis, Elevated Liver Enzymes, Lowered Platelets in 7 studies
Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.
| Excerpt | Relevance | Reference |
|---|---|---|
| "During pregnancy the placental 11beta-hydroxysteroid dehydrogenase 2 (11beta-HSD2) enzyme inactivates prednisolone by interconversion into prednisone, protecting the fetus from high levels of prednisolone." | 9.11 | The transplacental passage of prednisolone in pregnancies complicated by early-onset HELLP syndrome. ( Bruinse, HW; Franx, A; Huisjes, AJ; Schobben, AF; van Runnard Heimel, PJ, 2005) |
| "To investigate the effect of prednisolone on HELLP syndrome by assessing several markers of the inflammatory response and hepatic damage associated with HELLP syndrome." | 7.74 | HELLP syndrome is associated with an increased inflammatory response, which may be inhibited by administration of prednisolone. ( Bruinse, HW; Franx, A; Heijnen, CJ; Huisjes, AJ; Kavelaars, A; Peters, WH; van Runnard Heimel, PJ, 2008) |
| "During pregnancy the placental 11beta-hydroxysteroid dehydrogenase 2 (11beta-HSD2) enzyme inactivates prednisolone by interconversion into prednisone, protecting the fetus from high levels of prednisolone." | 5.11 | The transplacental passage of prednisolone in pregnancies complicated by early-onset HELLP syndrome. ( Bruinse, HW; Franx, A; Huisjes, AJ; Schobben, AF; van Runnard Heimel, PJ, 2005) |
| "To investigate the effect of prednisolone on HELLP syndrome by assessing several markers of the inflammatory response and hepatic damage associated with HELLP syndrome." | 3.74 | HELLP syndrome is associated with an increased inflammatory response, which may be inhibited by administration of prednisolone. ( Bruinse, HW; Franx, A; Heijnen, CJ; Huisjes, AJ; Kavelaars, A; Peters, WH; van Runnard Heimel, PJ, 2008) |
| "Randomized controlled trials comparing any corticosteroid with placebo, no treatment, or other drug; or comparing one corticosteroid with another corticosteroid or dosage in women with HELLP syndrome." | 2.46 | Corticosteroids for HELLP (hemolysis, elevated liver enzymes, low platelets) syndrome in pregnancy. ( Chandra, S; Dowswell, T; Hofmeyr, GJ; Woudstra, DM, 2010) |
| "The coincidence of HELLP syndrome and cortical blindness is an uncommon but very dramatic event, for the patient as well as the obstetrician." | 1.30 | Acute onset of blindness during labor: report of a case of transient cortical blindness in association with HELLP syndrome. ( Ebert, AD; Entezami, M; Hopp, HS; Runkel, S; Weitzel, HK, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| van Runnard Heimel, PJ | 2 |
| Kavelaars, A | 1 |
| Heijnen, CJ | 1 |
| Peters, WH | 1 |
| Huisjes, AJ | 2 |
| Franx, A | 2 |
| Bruinse, HW | 2 |
| Woudstra, DM | 1 |
| Chandra, S | 1 |
| Hofmeyr, GJ | 1 |
| Dowswell, T | 1 |
| Mathieu, N | 1 |
| Ledigabel, JF | 1 |
| Schobben, AF | 1 |
| Lowe, PM | 1 |
| Fryer, J | 1 |
| Shumack, S | 1 |
| Leclercq, G | 1 |
| Subtil, D | 1 |
| Dubos, JP | 1 |
| Pagniez, D | 1 |
| Codaccioni, X | 1 |
| Puech, F | 1 |
| Ebert, AD | 1 |
| Hopp, HS | 1 |
| Entezami, M | 1 |
| Runkel, S | 1 |
| Weitzel, HK | 1 |
1 review available for prednisolone and Hemolysis, Elevated Liver Enzymes, Lowered Platelets
| Article | Year |
|---|---|
Corticosteroids for HELLP (hemolysis, elevated liver enzymes, low platelets) syndrome in pregnancy.
Topics: Adrenal Cortex Hormones; Betamethasone; Dexamethasone; Female; HELLP Syndrome; Humans; Maternal Mort | 2010 |
1 trial available for prednisolone and Hemolysis, Elevated Liver Enzymes, Lowered Platelets
| Article | Year |
|---|---|
The transplacental passage of prednisolone in pregnancies complicated by early-onset HELLP syndrome.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Anti-Inflammatory Agents; Female; Fetus; HELLP Syndrome | 2005 |
5 other studies available for prednisolone and Hemolysis, Elevated Liver Enzymes, Lowered Platelets
| Article | Year |
|---|---|
HELLP syndrome is associated with an increased inflammatory response, which may be inhibited by administration of prednisolone.
Topics: Adult; Anti-Inflammatory Agents; Biomarkers; Case-Control Studies; Female; HELLP Syndrome; Humans; I | 2008 |
[Pre-eclampsia and facial paralysis].
Topics: Adult; Antihypertensive Agents; Bell Palsy; Female; HELLP Syndrome; Humans; Pre-Eclampsia; Prednisol | 2011 |
Pemphigoid gestationis occurring in a patient with HELLP syndrome.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents; Cesarean Section; Female; Fluorescent Antibod | 1996 |
[Corticoids and HELLP syndrome. A new indicator?].
Topics: Adult; Female; Glucocorticoids; HELLP Syndrome; Humans; Prednisolone; Pregnancy | 1997 |
Acute onset of blindness during labor: report of a case of transient cortical blindness in association with HELLP syndrome.
Topics: Adult; Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Anticonvulsants; Antihypertensive Agents; A | 1999 |