Page last updated: 2024-11-06

prednisolone and Hemangioma Thrombocytopenia Syndrome

prednisolone has been researched along with Hemangioma Thrombocytopenia Syndrome in 11 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Research Excerpts

ExcerptRelevanceReference
"There is currently no consensus on the second-line management of Kaposiform hemangioendothelioma (KHE) that was resistant to prednisolone and vincristine."7.81Successful treatment of Kaposiform hemangioendothelioma with everolimus. ( Ito, S; Miyazaki, O; Mori, T; Nakazawa, A; Terashima, K; Uno, T, 2015)
"Sirolimus was added; he became transfusion independent with no further bleeding and reduction in tumor size."5.48Kaposiform hemangioendothelioma with Kasabach-Merritt phenomenon in an infant: Successful treatment with prednisolone, vincristine, and addition of sirolimus. ( Cashell, J; Helm, K; Smink, GM; Xavier, F, 2018)
"Sirolimus was effective and safe for the treatment of progressive KHE."5.46Sirolimus for the treatment of progressive kaposiform hemangioendothelioma: A multicenter retrospective study. ( Chen, S; Ji, Y; Li, K; Li, Y; Liu, X; Lu, G; Tang, X; Wang, C; Wang, Q; Wu, H; Xia, C; Xiang, B; Xu, T; Xu, Z; Yang, G; Yang, K; Yao, W, 2017)
"Sirolimus is an effective therapy for children with kaposiform hemangioendothelioma with or without the Kasabach-Merritt phenomenon."3.88 ( Dillingham, CS; Givner, LB; McLean, TW; Rinker, EK; Russell, TB, 2018)
"There is currently no consensus on the second-line management of Kaposiform hemangioendothelioma (KHE) that was resistant to prednisolone and vincristine."3.81Successful treatment of Kaposiform hemangioendothelioma with everolimus. ( Ito, S; Miyazaki, O; Mori, T; Nakazawa, A; Terashima, K; Uno, T, 2015)
"Sirolimus was added; he became transfusion independent with no further bleeding and reduction in tumor size."1.48Kaposiform hemangioendothelioma with Kasabach-Merritt phenomenon in an infant: Successful treatment with prednisolone, vincristine, and addition of sirolimus. ( Cashell, J; Helm, K; Smink, GM; Xavier, F, 2018)
"Sirolimus was effective and safe for the treatment of progressive KHE."1.46Sirolimus for the treatment of progressive kaposiform hemangioendothelioma: A multicenter retrospective study. ( Chen, S; Ji, Y; Li, K; Li, Y; Liu, X; Lu, G; Tang, X; Wang, C; Wang, Q; Wu, H; Xia, C; Xiang, B; Xu, T; Xu, Z; Yang, G; Yang, K; Yao, W, 2017)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's10 (90.91)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Ji, Y2
Chen, S2
Zhou, J1
Yang, K2
Zhang, X1
Xiang, B2
Qiu, T1
Gong, X1
Zhang, Z1
Lan, Y1
Hu, F1
Kong, F1
Qiu, Q1
Zhang, Y1
Li, K1
Xu, Z1
Yao, W1
Lu, G1
Liu, X1
Xia, C1
Wang, Q1
Li, Y1
Wang, C1
Yang, G1
Tang, X1
Xu, T1
Wu, H1
Mizutani, K1
Umaoka, A1
Tsuda, K1
Kakeda, M1
Habe, K1
Yamanaka, K1
Suyama, M1
Mizutani, H1
Russell, TB1
Rinker, EK1
Dillingham, CS1
Givner, LB1
McLean, TW1
Gültekin, ND1
Yilmaz, FH1
Altunhan, H1
Findik, S1
Tokgöz, H1
Çalişkan, Ü1
Cashell, J1
Smink, GM1
Helm, K1
Xavier, F1
Fichel, F1
Eschard, C1
Zachar, D1
Munzer, M1
Bernard, P1
Grange, F1
Downing, A1
Chauhan, A1
Lotterman, C1
Craver, R1
Warrier, R1
Uno, T1
Ito, S1
Nakazawa, A1
Miyazaki, O1
Mori, T1
Terashima, K1
Tamai, N1
Hashii, Y1
Osuga, K1
Chihara, T1
Morii, E1
Aozasa, K1
Yoshikawa, H1
Jahnel, J1
Lackner, H1
Reiterer, F1
Urlesberger, B1
Urban, C1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Different Doses of Sirolimus for the Maintenance Treatment of Kaposiform Hemangioendothelioma: a Randomized Controlled Trial[NCT05324384]Phase 230 participants (Anticipated)Interventional2022-04-05Recruiting
Sirolimus Versus Sirolimus Plus Prednisolone for Kaposiform Hemangioendothelioma With Kasabach-Merritt Syndrome[NCT03188068]Phase 230 participants (Actual)Interventional2017-06-01Completed
Different Doses of Sirolimus for Kaposiform Hemangioendothelioma: a Randomized Clinical Trial[NCT04775173]Phase 279 participants (Actual)Interventional2021-02-17Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for prednisolone and Hemangioma Thrombocytopenia Syndrome

ArticleYear
Sirolimus plus prednisolone vs sirolimus monotherapy for kaposiform hemangioendothelioma: a randomized clinical trial.
    Blood, 2022, 03-17, Volume: 139, Issue:11

    Topics: Hemangioendothelioma; Humans; Infant; Kasabach-Merritt Syndrome; Prednisolone; Sarcoma, Kaposi; Siro

2022
Sirolimus plus prednisolone vs sirolimus monotherapy for kaposiform hemangioendothelioma: a randomized clinical trial.
    Blood, 2022, 03-17, Volume: 139, Issue:11

    Topics: Hemangioendothelioma; Humans; Infant; Kasabach-Merritt Syndrome; Prednisolone; Sarcoma, Kaposi; Siro

2022
Sirolimus plus prednisolone vs sirolimus monotherapy for kaposiform hemangioendothelioma: a randomized clinical trial.
    Blood, 2022, 03-17, Volume: 139, Issue:11

    Topics: Hemangioendothelioma; Humans; Infant; Kasabach-Merritt Syndrome; Prednisolone; Sarcoma, Kaposi; Siro

2022
Sirolimus plus prednisolone vs sirolimus monotherapy for kaposiform hemangioendothelioma: a randomized clinical trial.
    Blood, 2022, 03-17, Volume: 139, Issue:11

    Topics: Hemangioendothelioma; Humans; Infant; Kasabach-Merritt Syndrome; Prednisolone; Sarcoma, Kaposi; Siro

2022

Other Studies

10 other studies available for prednisolone and Hemangioma Thrombocytopenia Syndrome

ArticleYear
Sirolimus for the treatment of progressive kaposiform hemangioendothelioma: A multicenter retrospective study.
    International journal of cancer, 2017, 08-15, Volume: 141, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Child; C

2017
Sirolimus for the treatment of progressive kaposiform hemangioendothelioma: A multicenter retrospective study.
    International journal of cancer, 2017, 08-15, Volume: 141, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Child; C

2017
Sirolimus for the treatment of progressive kaposiform hemangioendothelioma: A multicenter retrospective study.
    International journal of cancer, 2017, 08-15, Volume: 141, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Child; C

2017
Sirolimus for the treatment of progressive kaposiform hemangioendothelioma: A multicenter retrospective study.
    International journal of cancer, 2017, 08-15, Volume: 141, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Child; C

2017
Sirolimus for the treatment of progressive kaposiform hemangioendothelioma: A multicenter retrospective study.
    International journal of cancer, 2017, 08-15, Volume: 141, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Child; C

2017
Sirolimus for the treatment of progressive kaposiform hemangioendothelioma: A multicenter retrospective study.
    International journal of cancer, 2017, 08-15, Volume: 141, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Child; C

2017
Sirolimus for the treatment of progressive kaposiform hemangioendothelioma: A multicenter retrospective study.
    International journal of cancer, 2017, 08-15, Volume: 141, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Child; C

2017
Sirolimus for the treatment of progressive kaposiform hemangioendothelioma: A multicenter retrospective study.
    International journal of cancer, 2017, 08-15, Volume: 141, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Child; C

2017
Sirolimus for the treatment of progressive kaposiform hemangioendothelioma: A multicenter retrospective study.
    International journal of cancer, 2017, 08-15, Volume: 141, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Child; C

2017
Successful combination therapy of propranolol and prednisolone for a case with congenital Kasabach-Merritt syndrome.
    The Journal of dermatology, 2017, Volume: 44, Issue:12

    Topics: Glucocorticoids; Humans; Infant, Newborn; Kasabach-Merritt Syndrome; Male; Prednisolone; Propranolol

2017
    Pediatrics, 2018, Volume: 141, Issue:Suppl 5

    Topics: Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Drug Therapy,

2018
Coexistence of Kasabach-Merritt Syndrome and placental chorioangioma in a premature infant.
    Journal of neonatal-perinatal medicine, 2018, Volume: 11, Issue:2

    Topics: Anti-Inflammatory Agents; Comorbidity; Fatal Outcome; Female; Hemangioma; Humans; Infant, Newborn; K

2018
Kaposiform hemangioendothelioma with Kasabach-Merritt phenomenon in an infant: Successful treatment with prednisolone, vincristine, and addition of sirolimus.
    Pediatric blood & cancer, 2018, Volume: 65, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Blood Coagulation Disorders; Child; Hemangioendothel

2018
[Kaposiform haemangioendothelioma associated with B-cell acute lymphoblastic leukemia].
    Annales de dermatologie et de venereologie, 2013, Volume: 140, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Biopsy; Combined Modality Therapy

2013
Giant vascular malformation with thrombocytopenia in a newborn.
    Clinical pediatrics, 2013, Volume: 52, Issue:11

    Topics: Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Arm; Female; Hemangioendothelioma; Huma

2013
Successful treatment of Kaposiform hemangioendothelioma with everolimus.
    Pediatric blood & cancer, 2015, Volume: 62, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Drug Resistance, Neoplasm; Everolimus; Hemang

2015
Kaposiform hemangioendothelioma arising in the deltoid muscle without the Kasabach-Merritt phenomenon.
    Skeletal radiology, 2010, Volume: 39, Issue:10

    Topics: Antineoplastic Agents, Hormonal; Deltoid Muscle; Diagnosis, Differential; Disseminated Intravascular

2010
Kaposiform hemangioendothelioma with Kasabach-Merritt phenomenon: from vincristine to sirolimus.
    Klinische Padiatrie, 2012, Volume: 224, Issue:6

    Topics: Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineopla

2012