prednisolone has been researched along with Glaucoma, Suspect in 60 studies
Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare adverse intraocular pressure (IOP) spikes in patients receiving intravitreal triamcinolone acetonide (IVTA) in 2 cohorts: (i) patients who underwent a topical prednisolone acetate trial (PAT) without incurring a short-term IOP rise, and (ii) control patients who did not undergo a PAT." | 9.14 | A trial of topical prednisolone acetate before intravitreal triamcinolone acetonide decreases intraocular pressure spikes. ( Gale, J; Hollands, H; Hollands, S; Seif, G, 2010) |
| "To compare intraocular pressure (IOP) outcomes between 2 common, commercially available corticosteroid drops: difluprednate ophthalmic emulsion 0." | 7.85 | Comparison of prednisolone acetate 1.0% and difluprednate ophthalmic emulsion 0.05% after cataract surgery: Incidence of postoperative steroid-induced ocular hypertension. ( Ernest, P; McBain, M; Mian, SI; Musch, DC; Niziol, LM; Person, E; Tijunelis, MA, 2017) |
| "We have previously shown that tissue plasminogen activator (tPA) injected in the vitreous of sheep, reduced or prevented the elevation of the intraocular pressure (IOP) normally produced by the instillation of 1% prednisolone." | 7.80 | Tissue plasminogen activator reduces the elevated intraocular pressure induced by prednisolone in sheep. ( Candia, OA; Danias, J; Gerometta, RM, 2014) |
| "To identify changes in intraocular pressure (IOP) after vitreoretinal surgical procedures in eyes that received either difluprednate ophthalmic emulsion 0." | 7.80 | Incidence of steroid-induced ocular hypertension after vitreoretinal surgery with difluprednate versus prednisolone acetate. ( Connors, DB; Fine, HF; Jeng, KW; Prenner, JL; Roth, D; Wheatley, HM, 2014) |
| "To describe a clinically observed reduction in intraocular pressure (IOP) without increased allograft rejection in known "steroid responders" using loteprednol etabonate 0." | 7.75 | Attenuation of ocular hypertension with the use of topical loteprednol etabonate 0.5% in steroid responders after corneal transplantation. ( Djalilian, AR; Holland, EJ; Sanderson, JP, 2009) |
| "Rimexolone has a low IOP-elevating potential, comparable to that of fluorometholone and less than that of dexamethasone sodium phosphate and prednisolone acetate." | 6.68 | Intraocular pressure-raising potential of 1.0% rimexolone in patients responding to corticosteroids. ( Assil, K; Bartlett, JD; Leibowitz, HM; McQuirter, H; Rich, R; Stewart, R, 1996) |
| "The aim of this study was to investigate the diagnostic value of a topical prednisolone acetate 1% provocative test for steroid-induced ocular hypertension before intravitreal triamcinolone acetonide injection." | 5.34 | The value of prednisolone acetate provocative test before intravitreal triamcinolone acetonide injections. ( Abdullatif, AM; Fouad, HM; Helmy, YAH; Macky, TA; Mansour, K; Saady, AM, 2020) |
| "Patients older than 18 years with intraocular pressure (IOP) of more than 18 mmHg for whom the clinician decided SLT was the appropriately indicated therapy were randomized to 1 of 3 groups in a ratio of 1:1:1 as follows: ketorolac 0." | 5.30 | SALT Trial: Steroids after Laser Trabeculoplasty: Impact of Short-Term Anti-inflammatory Treatment on Selective Laser Trabeculoplasty Efficacy. ( Albeiruti, E; Fajardo, R; Goldberg, JL; Groth, SL; Loewen, N; Nunez, M; Schuman, JS; Sharpsten, L, 2019) |
| "In dogs that underwent cataract surgery via phacoemulsification, a full week of topical prednisolone acetate treatment prior to surgery did not decrease postoperative inflammation, compared with commencement of topical prednisolone acetate treatment the evening prior to surgery, and was associated with a greater incidence of postoperative ocular hypertension." | 5.16 | Effects of one-week versus one-day preoperative treatment with topical 1% prednisolone acetate in dogs undergoing phacoemulsification. ( Hendrix, DV; McLean, NJ; Vaughn, RK; Ward, DA, 2012) |
| "To compare adverse intraocular pressure (IOP) spikes in patients receiving intravitreal triamcinolone acetonide (IVTA) in 2 cohorts: (i) patients who underwent a topical prednisolone acetate trial (PAT) without incurring a short-term IOP rise, and (ii) control patients who did not undergo a PAT." | 5.14 | A trial of topical prednisolone acetate before intravitreal triamcinolone acetonide decreases intraocular pressure spikes. ( Gale, J; Hollands, H; Hollands, S; Seif, G, 2010) |
| "To determine whether a topical ophthalmic diclofenac sodium formulation containing a proprietary polymeric drug delivery system (ISV-205), when dosed concomitantly with 1% prednisolone acetate, is effective in blocking the intraocular pressure (IOP) response in humans." | 5.10 | Prevention of corticosteroid-induced intraocular pressure elevation using ISV-205. ( Stewart, WC, 2003) |
| "The case concerns an 81-year-old woman on treatment with a topical fixed combination of timolol and brimonidine who was diagnosed in the Emergency Department with acute anterior granulomatous hypertensive uveitis." | 3.88 | Hypertensive acute granulomatous anterior uveitis as a side effect of topical brimonidine. ( Arciniegas-Perasso, CA; Clemente-Tomás, R; Duch-Samper, AM; García-Ibor, F; Hervás-Hernandis, JM; Ruiz-Del Río, N, 2018) |
| "To compare intraocular pressure (IOP) outcomes between 2 common, commercially available corticosteroid drops: difluprednate ophthalmic emulsion 0." | 3.85 | Comparison of prednisolone acetate 1.0% and difluprednate ophthalmic emulsion 0.05% after cataract surgery: Incidence of postoperative steroid-induced ocular hypertension. ( Ernest, P; McBain, M; Mian, SI; Musch, DC; Niziol, LM; Person, E; Tijunelis, MA, 2017) |
| "Prednisolone, the first-line treatment for children with nephrotic syndrome, causes severe side effects." | 3.80 | Early and frequent development of ocular hypertension in children with nephrotic syndrome. ( Ando, T; Hamada, R; Hamasaki, Y; Hataya, H; Honda, M; Ishikura, K; Kawaguchi, E; Miura, M; Morikawa, Y; Nagaoka, Y; Noda, E; Sakai, T, 2014) |
| "To identify changes in intraocular pressure (IOP) after vitreoretinal surgical procedures in eyes that received either difluprednate ophthalmic emulsion 0." | 3.80 | Incidence of steroid-induced ocular hypertension after vitreoretinal surgery with difluprednate versus prednisolone acetate. ( Connors, DB; Fine, HF; Jeng, KW; Prenner, JL; Roth, D; Wheatley, HM, 2014) |
| "We have previously shown that tissue plasminogen activator (tPA) injected in the vitreous of sheep, reduced or prevented the elevation of the intraocular pressure (IOP) normally produced by the instillation of 1% prednisolone." | 3.80 | Tissue plasminogen activator reduces the elevated intraocular pressure induced by prednisolone in sheep. ( Candia, OA; Danias, J; Gerometta, RM, 2014) |
| "Intraocular pressure (IOP) was monitored by Perkins applanation tonometry in 16 normal sheep receiving topically administered prednisolone acetate, 0." | 3.76 | Suppression of corticosteroid-induced ocular hypertension in sheep by anecortave. ( Candia, OA; Gerometta, R; Millar, JC; Podos, SM, 2010) |
| "To describe a clinically observed reduction in intraocular pressure (IOP) without increased allograft rejection in known "steroid responders" using loteprednol etabonate 0." | 3.75 | Attenuation of ocular hypertension with the use of topical loteprednol etabonate 0.5% in steroid responders after corneal transplantation. ( Djalilian, AR; Holland, EJ; Sanderson, JP, 2009) |
| "In cases where prednisolone acetate was administered, we found a significant correlation between N363S heterozygosity and steroid-induced ocular hypertension." | 3.74 | The variant N363S of glucocorticoid receptor in steroid-induced ocular hypertension in Hungarian patients treated with photorefractive keratectomy. ( Bányász, I; Borgulya, G; Filkorn, T; Majnik, J; Nagy, ZZ; Szabó, V, 2007) |
| "Intraocular pressure was monitored by Perkins applanation tonometry in a group of 12 cows receiving topically administered prednisolone acetate in 1 eye 3 times a day for a period of 49 days after the establishment of baseline IOP values." | 3.72 | Steroid-induced ocular hypertension in normal cattle. ( Candia, OA; Danias, J; Gerometta, R; Malgor, LA; Mittag, T; Podos, SM; Wu, B, 2004) |
| " Initial presentation of the patient was bilateral iridocyclitis, for which he was treated with prednisolone acetate 1% every 2 hours for 6 months." | 3.70 | Systemic toxicity of topical and periocular corticosteroid therapy in an 11-year-old male with posterior uveitis. ( Cheng, L; Freeman, WR; Levi, L; Ozerdem, U; Scher, C; Song, MK, 2000) |
| "Rimexolone has a low IOP-elevating potential, comparable to that of fluorometholone and less than that of dexamethasone sodium phosphate and prednisolone acetate." | 2.68 | Intraocular pressure-raising potential of 1.0% rimexolone in patients responding to corticosteroids. ( Assil, K; Bartlett, JD; Leibowitz, HM; McQuirter, H; Rich, R; Stewart, R, 1996) |
| "Atopic dermatitis is a relatively common hereditary dermatologic condition." | 2.41 | Atopic dermatitis: a case report and current clinical review of systemic and ocular manifestations. ( Bachman, JA; Brandonisio, TM; Sears, JM, 2001) |
| "The risk of steroid-induced ocular hypertension may depend on age and ethnicity." | 1.62 | Risk of ocular hypertension in children treated with systemic glucocorticoid. ( Albertsen, BK; Glerup, M; Krag, S; Larsen, D, 2021) |
| "To estimate the burden of ocular complications like posterior subcapsular cataract (PSCC) and raised intra ocular pressure (IOP) in children with nephrotic syndrome on long term steroid therapy and to assess the correlation of cumulative dosage and duration of consumption of steroids with these ocular complications." | 1.40 | Ocular complications in children with nephrotic syndrome on long term oral steroids. ( Gaur, S; Iyengar, A; Joseph, M; Koshy, AS; Nityanandam, S; Phadke, KD; Subramanian, S; Vasudevan, A, 2014) |
| "Peripheral ulcerative keratitis is a destructive process involving perilimbal corneal inflammation and an overlying epithelial defect." | 1.37 | Peripheral ulcerative keratitis in a child. ( Ali, A; Leung, AK; Mireskandari, K, 2011) |
| "Prednisolone drops were discontinued and timolol was started." | 1.35 | Optic neuropathy after epi-LASIK. ( Lessell, S; Montezuma, SR; Pineda, R, 2008) |
| "A 9-year-old patient with leukemia received oral prednisolone at a dosage of 2." | 1.32 | Intraocular pressure profile of a child on a systemic corticosteroid. ( Chik, KW; Lam, DS; Li, RT; Ng, JS; Tham, CC, 2004) |
| " Reduction in the dosage of topical corticosteroid and medical treatment of the raised IOP resulted in resolution of the microcystic edema and interface fluid accumulation." | 1.31 | Interface fluid after laser in situ keratomileusis. ( Fogla, R; Padmanabhan, P; Rao, SK, 2001) |
| " These values were sustained throughout dosing but declined rapidly to baseline upon cessation of treatment." | 1.30 | Pharmacological validation of a feline model of steroid-induced ocular hypertension. ( Bhattacherjee, P; Graff, G; Paterson, CA; Spellman, JM; Yanni, JM, 1999) |
| "Steroid-induced ocular hypertension is generally attributed to alterations in the trabecular meshwork, reducing aqueous outflow." | 1.29 | Steroid-induced ocular hypertension in the presence of a functioning Molteno seton. ( Brian, G; Muecke, J, 1995) |
| "Pilocarpine was used to treat persistent epithelial defects or raised intraocular pressure." | 1.29 | Pilocarpine-associated allograft rejection in postkeratoplasty patients. ( Assil, KK; Massry, GG, 1995) |
| "A further two cases of ocular hypertension secondary to topical facial steroids are also described." | 1.29 | Extensive visual loss with topical facial steroids. ( Aggarwal, RK; Chong, NH; Guarro, M; Kheterpal, S; Potamitis, T; Shah, P, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.67) | 18.7374 |
| 1990's | 12 (20.00) | 18.2507 |
| 2000's | 19 (31.67) | 29.6817 |
| 2010's | 23 (38.33) | 24.3611 |
| 2020's | 5 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Sawada, M | 1 |
| Takachi, T | 1 |
| Watanabe, K | 1 |
| Tsuchiya, Y | 1 |
| Nishimura, K | 1 |
| Hotta, Y | 1 |
| Sato, M | 1 |
| Groth, SL | 1 |
| Albeiruti, E | 1 |
| Nunez, M | 1 |
| Fajardo, R | 1 |
| Sharpsten, L | 1 |
| Loewen, N | 1 |
| Schuman, JS | 1 |
| Goldberg, JL | 1 |
| Price, MO | 1 |
| Feng, MT | 1 |
| Price, FW | 1 |
| Krag, S | 1 |
| Larsen, D | 1 |
| Albertsen, BK | 1 |
| Glerup, M | 1 |
| Rajendrababu, S | 1 |
| Pallamparthy, S | 1 |
| Arunachalam, A | 1 |
| Uduman, MS | 1 |
| Srinivasan, S | 1 |
| Krishnadas, SR | 1 |
| Senthilkumar, VA | 1 |
| Tijunelis, MA | 1 |
| Person, E | 1 |
| Niziol, LM | 1 |
| Musch, DC | 1 |
| Ernest, P | 1 |
| McBain, M | 1 |
| Mian, SI | 1 |
| Shan, SW | 1 |
| Do, CW | 1 |
| Lam, TC | 1 |
| Kong, RPW | 1 |
| Li, KK | 1 |
| Chun, KM | 1 |
| Stamer, WD | 1 |
| To, CH | 1 |
| Clemente-Tomás, R | 1 |
| Arciniegas-Perasso, CA | 1 |
| Hervás-Hernandis, JM | 1 |
| García-Ibor, F | 1 |
| Ruiz-Del Río, N | 1 |
| Duch-Samper, AM | 1 |
| Rueda-Rueda, T | 1 |
| Sánchez-Vicente, LJ | 1 |
| Moruno-Rodríguez, A | 1 |
| Monge-Esquivel, J | 1 |
| Muñoz-Morales, A | 1 |
| López-Herrero, F | 1 |
| Saady, AM | 1 |
| Fouad, HM | 1 |
| Abdullatif, AM | 1 |
| Helmy, YAH | 1 |
| Macky, TA | 1 |
| Mansour, K | 1 |
| Faria-Correia, F | 1 |
| Ramos, I | 1 |
| Valbon, B | 1 |
| Luz, A | 1 |
| Roberts, CJ | 1 |
| Ambrósio, R | 1 |
| Gerometta, R | 6 |
| Kumar, S | 1 |
| Shah, S | 1 |
| Alvarez, L | 1 |
| Candia, O | 1 |
| Danias, J | 5 |
| Gaur, S | 1 |
| Joseph, M | 1 |
| Nityanandam, S | 1 |
| Subramanian, S | 1 |
| Koshy, AS | 1 |
| Vasudevan, A | 1 |
| Phadke, KD | 1 |
| Iyengar, A | 1 |
| Kawaguchi, E | 1 |
| Ishikura, K | 1 |
| Hamada, R | 1 |
| Nagaoka, Y | 1 |
| Morikawa, Y | 1 |
| Sakai, T | 1 |
| Hamasaki, Y | 1 |
| Hataya, H | 1 |
| Noda, E | 1 |
| Miura, M | 1 |
| Ando, T | 1 |
| Honda, M | 1 |
| Jeng, KW | 1 |
| Fine, HF | 1 |
| Wheatley, HM | 1 |
| Roth, D | 1 |
| Connors, DB | 1 |
| Prenner, JL | 1 |
| Jinapriya, D | 1 |
| D'Souza, M | 1 |
| Hollands, H | 2 |
| El-Defrawy, SR | 1 |
| Irrcher, I | 1 |
| Smallman, D | 1 |
| Farmer, JP | 1 |
| Cheung, J | 1 |
| Urton, T | 1 |
| Day, A | 1 |
| Sun, X | 1 |
| Campbell, RJ | 1 |
| Candia, OA | 6 |
| Gerometta, RM | 1 |
| Foster, DW | 1 |
| Ecker, AH | 1 |
| Zvolensky, MJ | 1 |
| Buckner, JD | 1 |
| Däster, S | 1 |
| Eppenberger-Castori, S | 1 |
| Hirt, C | 1 |
| Soysal, SD | 1 |
| Delko, T | 1 |
| Nebiker, CA | 1 |
| Weixler, B | 1 |
| Amicarella, F | 1 |
| Iezzi, G | 1 |
| Governa, V | 1 |
| Padovan, E | 1 |
| Mele, V | 1 |
| Sconocchia, G | 1 |
| Heberer, M | 1 |
| Terracciano, L | 1 |
| Kettelhack, C | 1 |
| Oertli, D | 1 |
| Spagnoli, GC | 1 |
| von Holzen, U | 1 |
| Tornillo, L | 1 |
| Droeser, RA | 1 |
| Zhu, W | 1 |
| Germain, C | 1 |
| Liu, Z | 1 |
| Sebastian, Y | 1 |
| Devi, P | 1 |
| Knockaert, S | 1 |
| Brohawn, P | 1 |
| Lehmann, K | 1 |
| Damotte, D | 1 |
| Validire, P | 1 |
| Yao, Y | 1 |
| Valge-Archer, V | 1 |
| Hammond, SA | 1 |
| Dieu-Nosjean, MC | 1 |
| Higgs, BW | 1 |
| Mendez, TL | 1 |
| De Chatterjee, A | 1 |
| Duarte, T | 1 |
| De Leon, J | 1 |
| Robles-Martinez, L | 1 |
| Das, S | 1 |
| Khurshid, SS | 1 |
| Siegel, JA | 1 |
| Kinney, KA | 1 |
| Prentoe, J | 1 |
| Verhoye, L | 1 |
| Velázquez Moctezuma, R | 1 |
| Buysschaert, C | 1 |
| Farhoudi, A | 1 |
| Wang, R | 1 |
| Alter, H | 1 |
| Meuleman, P | 1 |
| Bukh, J | 1 |
| Maejima, R | 1 |
| Uno, K | 1 |
| Iijima, K | 1 |
| Fujishima, F | 1 |
| Noguchi, T | 1 |
| Ara, N | 1 |
| Asano, N | 1 |
| Koike, T | 1 |
| Imatani, A | 1 |
| Shimosegawa, T | 1 |
| Man, S | 1 |
| Qiu, P | 1 |
| Li, J | 1 |
| Zhang, L | 1 |
| Gao, W | 1 |
| Taylor, DA | 1 |
| Perin, EC | 1 |
| Willerson, JT | 1 |
| Zierold, C | 1 |
| Resende, M | 1 |
| Carlson, M | 1 |
| Nestor, B | 1 |
| Wise, E | 1 |
| Orozco, A | 1 |
| Pepine, CJ | 1 |
| Henry, TD | 1 |
| Ellis, SG | 1 |
| Zhao, DX | 1 |
| Traverse, JH | 1 |
| Cooke, JP | 1 |
| Schutt, RC | 1 |
| Bhatnagar, A | 1 |
| Grant, MB | 1 |
| Lai, D | 1 |
| Johnstone, BH | 1 |
| Sayre, SL | 1 |
| Moyé, L | 1 |
| Ebert, RF | 1 |
| Bolli, R | 1 |
| Simari, RD | 1 |
| Cogle, CR | 1 |
| Pilleri, P | 1 |
| Joblin, C | 1 |
| Boulanger, F | 1 |
| Onaka, T | 1 |
| Morakinyo, MK | 1 |
| Chipinda, I | 1 |
| Hettick, J | 1 |
| Siegel, PD | 1 |
| Abramson, J | 1 |
| Strongin, R | 1 |
| Martincigh, BS | 1 |
| Simoyi, RH | 1 |
| Salehi, MM | 1 |
| Safarzadeh, MA | 1 |
| Sahraei, E | 1 |
| Nejad, SA | 1 |
| Morimoto, Y | 1 |
| Izumi, H | 1 |
| Yoshiura, Y | 1 |
| Tomonaga, T | 1 |
| Oyabu, T | 1 |
| Myojo, T | 1 |
| Kawai, K | 1 |
| Yatera, K | 1 |
| Shimada, M | 1 |
| Kubo, M | 1 |
| Yamamoto, K | 1 |
| Kitajima, S | 1 |
| Kuroda, E | 1 |
| Kawaguchi, K | 1 |
| Sasaki, T | 1 |
| Windsor, LC | 1 |
| Jessell, L | 1 |
| Lassiter, T | 1 |
| Benoit, E | 1 |
| Thiessen, CE | 1 |
| Tofflemire, KL | 1 |
| Makielski, KM | 1 |
| Ben-Shlomo, G | 1 |
| Whitley, RD | 1 |
| Allbaugh, RA | 1 |
| Viu, J | 1 |
| Armengou, L | 1 |
| Ríos, J | 1 |
| Cesarini, C | 1 |
| Jose-Cunilleras, E | 1 |
| Margesin, R | 1 |
| Zhang, DC | 1 |
| Frasson, D | 1 |
| Brouchkov, A | 1 |
| Jung, WY | 1 |
| Lee, HJ | 1 |
| Jeon, CO | 1 |
| Liu, J | 1 |
| Li, F | 1 |
| Tang, XD | 1 |
| Ma, J | 1 |
| Mao, M | 1 |
| Wu, FZ | 1 |
| Bai, SJ | 1 |
| Liu, YY | 1 |
| Han, CX | 1 |
| Li, XX | 1 |
| Liu, Y | 1 |
| Song, YH | 1 |
| Wu, ZY | 1 |
| Wang, FY | 1 |
| Kang, N | 1 |
| Tanaka, KI | 1 |
| Kanazawa, I | 1 |
| Miyake, H | 1 |
| Yano, S | 1 |
| Amano, C | 1 |
| Ishikawa, N | 1 |
| Maruyama, R | 1 |
| Sugimoto, T | 1 |
| Yin, Q | 1 |
| Tao, Y | 1 |
| Zhu, X | 1 |
| Zhou, Y | 1 |
| He, X | 1 |
| Cheng, L | 2 |
| Huang, Y | 1 |
| Li, D | 1 |
| Rangachari, D | 1 |
| VanderLaan, PA | 1 |
| Le, X | 1 |
| Folch, E | 1 |
| Kent, MS | 1 |
| Gangadharan, SP | 1 |
| Majid, A | 1 |
| Haspel, RL | 1 |
| Joseph, LJ | 1 |
| Huberman, MS | 1 |
| Costa, DB | 1 |
| Moussavian, MR | 1 |
| Laschke, MW | 1 |
| Schlachtenberger, G | 1 |
| von Heesen, M | 1 |
| Wagner, M | 1 |
| Glanemann, M | 1 |
| Menger, MD | 1 |
| Huang, OS | 1 |
| Mehta, JS | 1 |
| Htoon, HM | 1 |
| Tan, DT | 1 |
| Wong, TT | 1 |
| Dhingra, S | 1 |
| Williams, G | 1 |
| Pearson, A | 1 |
| Podos, SM | 4 |
| Sallam, A | 1 |
| Sheth, HG | 1 |
| Habot-Wilner, Z | 1 |
| Lightman, S | 1 |
| Erdurmus, M | 1 |
| Cohen, EJ | 1 |
| Yildiz, EH | 1 |
| Hammersmith, KM | 1 |
| Laibson, PR | 1 |
| Varssano, D | 1 |
| Rapuano, CJ | 1 |
| Holland, EJ | 1 |
| Djalilian, AR | 1 |
| Sanderson, JP | 1 |
| Spiga, MG | 1 |
| Borrás, T | 1 |
| Nazm, N | 1 |
| Dubey, S | 1 |
| Gandhi, M | 1 |
| Pegu, J | 1 |
| Millar, JC | 1 |
| Kaufman, PL | 1 |
| Seif, G | 1 |
| Hollands, S | 1 |
| Gale, J | 1 |
| Chang, DF | 1 |
| Tan, JJ | 1 |
| Tripodis, Y | 1 |
| Ge, Y | 1 |
| Ren, L | 1 |
| Panagis, L | 1 |
| Mittag, TW | 1 |
| Leung, AK | 1 |
| Mireskandari, K | 1 |
| Ali, A | 1 |
| McLean, NJ | 1 |
| Ward, DA | 1 |
| Hendrix, DV | 1 |
| Vaughn, RK | 1 |
| Chung, MS | 1 |
| Pepose, JS | 1 |
| El-Agha, MS | 1 |
| Cavanagh, HD | 1 |
| Al-Agha, S | 1 |
| Stewart, WC | 1 |
| Tham, CC | 2 |
| Ng, JS | 2 |
| Li, RT | 1 |
| Chik, KW | 1 |
| Lam, DS | 3 |
| Wu, B | 1 |
| Malgor, LA | 1 |
| Mittag, T | 1 |
| Kurian, M | 1 |
| Shetty, R | 1 |
| Shetty, BK | 1 |
| Devi, SA | 1 |
| Frucht-Pery, J | 1 |
| Landau, D | 1 |
| Raiskup, F | 1 |
| Orucov, F | 1 |
| Strassman, E | 1 |
| Blumenthal, EZ | 1 |
| Solomon, A | 1 |
| Szabó, V | 1 |
| Borgulya, G | 1 |
| Filkorn, T | 1 |
| Majnik, J | 1 |
| Bányász, I | 1 |
| Nagy, ZZ | 1 |
| Leung, DY | 1 |
| Li, FC | 1 |
| Kwong, YY | 1 |
| Chiu, TY | 1 |
| Fan, DS | 1 |
| Montezuma, SR | 1 |
| Lessell, S | 1 |
| Pineda, R | 1 |
| Muecke, J | 1 |
| Brian, G | 1 |
| Pang, G | 1 |
| Wang, Z | 1 |
| Zheng, W | 1 |
| Wang, W | 1 |
| Sun, Y | 1 |
| Massry, GG | 1 |
| Assil, KK | 1 |
| Aggarwal, RK | 1 |
| Potamitis, T | 1 |
| Chong, NH | 1 |
| Guarro, M | 1 |
| Shah, P | 1 |
| Kheterpal, S | 1 |
| Bartlett, JD | 3 |
| Horwitz, B | 1 |
| Laibovitz, R | 1 |
| Howes, JF | 1 |
| Woolley, TW | 1 |
| Adams, CM | 1 |
| Raizman, M | 1 |
| Leibowitz, HM | 1 |
| Rich, R | 1 |
| McQuirter, H | 1 |
| Stewart, R | 1 |
| Assil, K | 1 |
| BenEzra, D | 1 |
| Wysenbeek, YS | 1 |
| Cohen, E | 1 |
| Bhattacherjee, P | 1 |
| Paterson, CA | 1 |
| Spellman, JM | 1 |
| Graff, G | 1 |
| Yanni, JM | 1 |
| Ozerdem, U | 1 |
| Levi, L | 1 |
| Song, MK | 1 |
| Scher, C | 1 |
| Freeman, WR | 1 |
| Brandonisio, TM | 1 |
| Bachman, JA | 1 |
| Sears, JM | 1 |
| Wong, W | 1 |
| Law, RW | 1 |
| Hui, J | 1 |
| Wong, EN | 1 |
| Fogla, R | 1 |
| Rao, SK | 1 |
| Padmanabhan, P | 1 |
| Shaikh, NM | 1 |
| Shaikh, S | 1 |
| Singh, K | 1 |
| Manche, E | 1 |
| Tripathi, RC | 1 |
| Kipp, MA | 1 |
| Tripathi, BJ | 1 |
| Kirschner, BS | 1 |
| Borisuth, NS | 1 |
| Shevell, SK | 1 |
| Ernest, JT | 1 |
| Zhan, GL | 1 |
| Miranda, OC | 1 |
| Bito, LZ | 1 |
| Călugăru, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized, Double-masked, Placebo-controlled Evaluation of Netarsudil for Prevention of Corticosteroid-induced Intraocular Pressure Elevation[NCT03248037] | Phase 3 | 120 participants (Actual) | Interventional | 2017-09-05 | Completed | ||
| The Effect of Inhaled Corticosteroids on Intraocular Pressure in Patients With Ocular Hypertension or Controlled Glaucoma.[NCT02338362] | Phase 4 | 22 participants (Actual) | Interventional | 2014-09-30 | Completed | ||
| A Prospective, Multi-center, Controlled, Double-blind Study to Evaluate the Efficacy and Tolerability of a Steroid/Antibiotic Associated Treatment Following Cataract Extraction by Means of Phaco-emulsification[NCT02973880] | Phase 3 | 180 participants (Actual) | Interventional | 2017-10-15 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Intraocular pressure measurement exceeding 24 mm Hg or more than 10 mm Hg greater than the pre-randomization reading. (NCT03248037)
Timeframe: from date of randomization until the date of first documented intraocular pressure elevation exceeding defined threshold up to 9 months
| Intervention | Participants (Count of Participants) |
|---|---|
| Netarsudil | 11 |
| Placebo | 18 |
Adherence was calculated from self-reported study diaries and correlated to a counter that measured number of inhaled puffs built into the placebo metered-dose inhalers (NCT02338362)
Timeframe: Completion of study, up to 6 weeks
| Intervention | percentage of required doses (Mean) |
|---|---|
| Fluticasone | 93.6 |
| Saline Placebo | 96.1 |
Masked assessment of intraocular pressure using goldmann application tonometry. Mean of 2 measurements within 1 mmHg will be recorded. (NCT02338362)
Timeframe: week 6
| Intervention | mmHg (Mean) |
|---|---|
| Fluticasone | 14.7 |
| Saline Placebo | 14.8 |
best corrected logMAR visual acuity for each eye. 20/20 vision corresponds with a logMAR score of 0, while negative logMAR scores indicate better than 20/20 vision, values > 0.5 correspond with low vision, and values > 1.3 correspond with blindness. (NCT02338362)
Timeframe: week 6
| Intervention | logMAR (Mean) |
|---|---|
| Fluticasone | 0.15 |
| Saline Placebo | 0.15 |
Participants with 2 consecutive intraocular pressure measurements exceeding 20% increase from baseline were discontinued from study. (NCT02338362)
Timeframe: within 6-week observation period
| Intervention | participants (Number) | |
|---|---|---|
| elevation >20% | no elevation >20% | |
| Fluticasone | 1 | 9 |
| Saline Placebo | 0 | 10 |
subjective (reported) and objective (slit lamp examination) side-effects attributable to study medications (NCT02338362)
Timeframe: from baseline to week 6
| Intervention | participants (Number) | ||||
|---|---|---|---|---|---|
| lens opacity | throat discomfort | headache | difficulty sleeping | no adverse effects | |
| Fluticasone | 0 | 1 | 1 | 0 | 8 |
| Saline Placebo | 0 | 1 | 0 | 1 | 8 |
2 reviews available for prednisolone and Glaucoma, Suspect
| Article | Year |
|---|---|
Corticosteroid therapy of eye disease. Fifty years later.
Topics: Anti-Inflammatory Agents; Clinical Trials as Topic; Dexamethasone; Eye Diseases; Fluorometholone; Hu | 1996 |
Atopic dermatitis: a case report and current clinical review of systemic and ocular manifestations.
Topics: Adrenergic beta-Antagonists; Cataract; Conjunctivitis, Allergic; Corneal Edema; Dermatitis, Atopic; | 2001 |
11 trials available for prednisolone and Glaucoma, Suspect
| Article | Year |
|---|---|
SALT Trial: Steroids after Laser Trabeculoplasty: Impact of Short-Term Anti-inflammatory Treatment on Selective Laser Trabeculoplasty Efficacy.
Topics: Administration, Ophthalmic; Aged; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Fema | 2019 |
Randomized, Double-Masked Trial of Netarsudil 0.02% Ophthalmic Solution for Prevention of Corticosteroid-Induced Ocular Hypertension.
Topics: Adult; Aged; Aged, 80 and over; Benzoates; beta-Alanine; Double-Blind Method; Female; Follow-Up Stud | 2021 |
The value of prednisolone acetate provocative test before intravitreal triamcinolone acetonide injections.
Topics: Administration, Ophthalmic; Adult; Aged; Anti-Inflammatory Agents; Female; Glucocorticoids; Humans; | 2020 |
Anti-inflammatory therapy after selective laser trabeculoplasty: a randomized, double-masked, placebo-controlled clinical trial.
Topics: Aged; Aged, 80 and over; Analysis of Variance; Anti-Inflammatory Agents; Cross-Sectional Studies; Do | 2014 |
A trial of topical prednisolone acetate before intravitreal triamcinolone acetonide decreases intraocular pressure spikes.
Topics: Administration, Topical; Aged; Choroidal Neovascularization; Follow-Up Studies; Glucocorticoids; Hum | 2010 |
Effects of one-week versus one-day preoperative treatment with topical 1% prednisolone acetate in dogs undergoing phacoemulsification.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Cataract; Dog Diseases; Dogs; Drug Admin | 2012 |
Prevention of corticosteroid-induced intraocular pressure elevation using ISV-205.
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; D | 2003 |
Randomized trial of early phacoemulsification versus peripheral iridotomy to prevent intraocular pressure rise after acute primary angle closure.
Topics: Acute Disease; Aged; Antihypertensive Agents; Cataract; Female; Follow-Up Studies; Glaucoma, Angle-C | 2008 |
Intraocular pressure response to loteprednol etabonate in known steroid responders.
Topics: Adolescent; Adult; Aged; Androstadienes; Anti-Inflammatory Agents; Double-Blind Method; Drug Adminis | 1993 |
Identification of high intraocular pressure responders to topical ophthalmic corticosteroids.
Topics: Adult; Circadian Rhythm; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Ag | 1993 |
Intraocular pressure-raising potential of 1.0% rimexolone in patients responding to corticosteroids.
Topics: Administration, Topical; Adult; Aged; Anti-Inflammatory Agents; Cross-Over Studies; Dexamethasone; D | 1996 |
47 other studies available for prednisolone and Glaucoma, Suspect
| Article | Year |
|---|---|
Steroid-induced ocular hypertensive response in pediatric patients with acute lymphoblastic leukemia.
Topics: Adrenal Cortex Hormones; Child; Child, Preschool; Female; Glaucoma; Glucocorticoids; Humans; Intraoc | 2023 |
Risk of ocular hypertension in children treated with systemic glucocorticoid.
Topics: Adolescent; Child; Child, Preschool; Denmark; Dexamethasone; Dose-Response Relationship, Drug; Femal | 2021 |
Incidence and risk factors for postoperative intraocular pressure response to topical prednisolone eye drops in patients undergoing phacoemulsification.
Topics: Aged; Humans; Incidence; Intraocular Pressure; Middle Aged; Ocular Hypertension; Ophthalmic Solution | 2021 |
Comparison of prednisolone acetate 1.0% and difluprednate ophthalmic emulsion 0.05% after cataract surgery: Incidence of postoperative steroid-induced ocular hypertension.
Topics: Cataract Extraction; Fluprednisolone; Glucocorticoids; Humans; Incidence; Intraocular Pressure; Ocul | 2017 |
New Insight of Common Regulatory Pathways in Human Trabecular Meshwork Cells in Response to Dexamethasone and Prednisolone Using an Integrated Quantitative Proteomics: SWATH and MRM-HR Mass Spectrometry.
Topics: Adult; Aged; Cell Line; Child, Preschool; Connective Tissue Growth Factor; Dexamethasone; Extracellu | 2017 |
Hypertensive acute granulomatous anterior uveitis as a side effect of topical brimonidine.
Topics: Acute Disease; Adrenergic alpha-2 Receptor Agonists; Aged, 80 and over; Brimonidine Tartrate; Conjun | 2018 |
Bilateral acute iris depigmentation and bilateral acute iris transillumination syndrome.
Topics: Acute Disease; Adult; Antihypertensive Agents; Diagnosis, Differential; Drug Therapy, Combination; E | 2019 |
Scheimpflug-based tomography and biomechanical assessment in pressure-induced stromal keratopathy.
Topics: Antihypertensive Agents; Biomechanical Phenomena; Corneal Diseases; Corneal Pachymetry; Corneal Stro | 2013 |
Reduction of steroid-induced intraocular pressure elevation in sheep by tissue plasminogen activator.
Topics: Animals; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Female; Fibr | 2013 |
Ocular complications in children with nephrotic syndrome on long term oral steroids.
Topics: Administration, Oral; Adolescent; Cataract; Child; Child, Preschool; Cross-Sectional Studies; Female | 2014 |
Early and frequent development of ocular hypertension in children with nephrotic syndrome.
Topics: Adolescent; Adrenergic beta-Antagonists; Anti-Inflammatory Agents; Antihypertensive Agents; Child; C | 2014 |
Incidence of steroid-induced ocular hypertension after vitreoretinal surgery with difluprednate versus prednisolone acetate.
Topics: Emulsions; Female; Fluprednisolone; Glucocorticoids; Humans; Incidence; Intraocular Pressure; Male; | 2014 |
Tissue plasminogen activator reduces the elevated intraocular pressure induced by prednisolone in sheep.
Topics: Animals; Anterior Chamber; Disease Models, Animal; Glucocorticoids; Intraocular Pressure; Ocular Hyp | 2014 |
Topics: Acid-Base Imbalance; Acidosis, Renal Tubular; Aged; Air Pollution, Indoor; Amino Acid Substitution; | 2015 |
Incidence and Risk Factors of Elevated Intraocular Pressure Following Deep Anterior Lamellar Keratoplasty.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Corneal Transplantation; Cyclosporine; Dexamethasone | 2016 |
Severe, permanent orbital disease in herpes zoster ophthalmicus.
Topics: Acyclovir; Antiviral Agents; Blepharoptosis; Conjunctival Diseases; Drug Therapy, Combination; Edema | 2008 |
Steroid-induced ocular hypertension in normal sheep.
Topics: Administration, Topical; Animals; Disease Models, Animal; Glucocorticoids; Intraocular Pressure; Ocu | 2009 |
Outcome of raised intraocular pressure in uveitic eyes with and without a corticosteroid-induced hypertensive response.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Chronic Disease; Female; Gla | 2009 |
Steroid-induced intraocular pressure elevation or glaucoma after penetrating keratoplasty in patients with keratoconus or Fuchs dystrophy.
Topics: Adolescent; Adult; Aged; Androstadienes; Female; Fluorometholone; Fuchs' Endothelial Dystrophy; Glau | 2009 |
Attenuation of ocular hypertension with the use of topical loteprednol etabonate 0.5% in steroid responders after corneal transplantation.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Androstadienes; Anti-Inflammato | 2009 |
Treatment of sheep steroid-induced ocular hypertension with a glucocorticoid-inducible MMP1 gene therapy virus.
Topics: Adenoviridae; Animals; Anterior Chamber; Disease Models, Animal; Female; Gene Expression Regulation, | 2010 |
Re: Outcome of raised intraocular pressure in uveitic eyes with and without a corticosteroid-induced hypertensive response.
Topics: Acute Disease; Antihypertensive Agents; Chronic Disease; Glaucoma; Glucocorticoids; Humans; Intraocu | 2010 |
Suppression of corticosteroid-induced ocular hypertension in sheep by anecortave.
Topics: Administration, Topical; Angiogenesis Inhibitors; Animals; Aqueous Humor; Disease Models, Animal; Fe | 2010 |
Suppression and reduction of corticosteroid-induced ocular hypertension by anecortave in sheep.
Topics: Angiogenesis Inhibitors; Animals; Disease Models, Animal; Glucocorticoids; Intraocular Pressure; Ocu | 2010 |
Risk factors for steroid response among cataract patients.
Topics: Administration, Topical; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Axial Length, Eye; | 2011 |
Gene expression changes in steroid-induced IOP elevation in bovine trabecular meshwork.
Topics: Animals; Anti-Inflammatory Agents; Cattle; Computational Biology; Disease Models, Animal; Female; Ge | 2011 |
Peripheral ulcerative keratitis in a child.
Topics: Child; Corneal Ulcer; Eye Pain; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Methotrex | 2011 |
Confocal microscopic findings in a case of delayed-onset bilateral diffuse lamellar keratitis after laser in situ keratomileusis.
Topics: Adult; Cornea; Cyclosporine; Female; Humans; Keratitis; Keratomileusis, Laser In Situ; Microscopy, C | 2002 |
Intraocular pressure profile of a child on a systemic corticosteroid.
Topics: Administration, Oral; Child; Female; Glucocorticoids; Humans; Intraocular Pressure; Ocular Hypertens | 2004 |
Steroid-induced ocular hypertension in normal cattle.
Topics: Animals; Cattle; Disease Models, Animal; Female; Glucocorticoids; Intraocular Pressure; Ocular Hyper | 2004 |
In vivo confocal microscopic findings of interlamellar stromal keratopathy induced by elevated intraocular pressure.
Topics: Acetazolamide; Adult; Antihypertensive Agents; Corneal Diseases; Corneal Stroma; Drug Therapy, Combi | 2006 |
Early transient visual acuity loss after LASIK due to steroid-induced elevation of intraocular pressure.
Topics: Adult; Corneal Topography; Female; Glucocorticoids; Humans; Intraocular Pressure; Keratomileusis, La | 2007 |
The variant N363S of glucocorticoid receptor in steroid-induced ocular hypertension in Hungarian patients treated with photorefractive keratectomy.
Topics: Adult; Corneal Surgery, Laser; Female; Fluorometholone; Genetic Predisposition to Disease; Genetic V | 2007 |
Optic neuropathy after epi-LASIK.
Topics: Adult; Glucocorticoids; Humans; Keratomileusis, Laser In Situ; Male; Myopia; Ocular Hypertension; Op | 2008 |
Steroid-induced ocular hypertension in the presence of a functioning Molteno seton.
Topics: Adolescent; Cataract Extraction; Female; Glaucoma; Humans; Intraocular Pressure; Lenses, Intraocular | 1995 |
[Glucocorticoid-induced ocular hypertension after photorefractive keratectomy].
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Cornea; Female; Glaucoma; Humans; Laser Th | 1995 |
Pilocarpine-associated allograft rejection in postkeratoplasty patients.
Topics: Aged; Aged, 80 and over; Corneal Diseases; Female; Graft Rejection; Humans; Keratoplasty, Penetratin | 1995 |
Extensive visual loss with topical facial steroids.
Topics: Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents; Clobetasol; Dermatitis, Atopic | 1993 |
Increased intraocular pressure during treatment for chronic uveitis.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Chronic Disease; Dexamethas | 1997 |
Pharmacological validation of a feline model of steroid-induced ocular hypertension.
Topics: Administration, Topical; Androstadienes; Animals; Cats; Dexamethasone; Disease Models, Animal; Femal | 1999 |
Systemic toxicity of topical and periocular corticosteroid therapy in an 11-year-old male with posterior uveitis.
Topics: Acanthosis Nigricans; Administration, Topical; Anti-Inflammatory Agents; Cataract; Child; Cushing Sy | 2000 |
Ocular complications of paediatric patients with nephrotic syndrome.
Topics: Adolescent; Cataract; Child; Child, Preschool; Cross-Sectional Studies; Eye Diseases; Female; Glucoc | 2001 |
Interface fluid after laser in situ keratomileusis.
Topics: Administration, Topical; Anti-Inflammatory Agents; Body Fluids; Cornea; Corneal Edema; Glucocorticoi | 2001 |
Progression to end-stage glaucoma after laser in situ keratomileusis.
Topics: Adult; Corneal Edema; Disease Progression; Glaucoma; Glucocorticoids; Humans; Intraocular Pressure; | 2002 |
Ocular toxicity of prednisone in pediatric patients with inflammatory bowel disease.
Topics: Adolescent; Adult; Cataract; Child; Child, Preschool; Colitis, Ulcerative; Crohn Disease; Female; Hu | 1992 |
Steroid glaucoma: corticosteroid-induced ocular hypertension in cats.
Topics: Administration, Topical; Animals; Cats; Dexamethasone; Dose-Response Relationship, Drug; Female; Mal | 1992 |
[Genetic aspects in hypertensive uveitis].
Topics: Acute Disease; Aged; Cortisone; Glaucoma; Glaucoma, Open-Angle; Humans; Middle Aged; Ocular Hyperten | 1986 |