Page last updated: 2024-11-06

prednisolone and Gingival Overgrowth

prednisolone has been researched along with Gingival Overgrowth in 6 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Gingival Overgrowth: Excessive growth of the gingiva either by an increase in the size of the constituent cells (GINGIVAL HYPERTROPHY) or by an increase in their number (GINGIVAL HYPERPLASIA). (From Jablonski's Dictionary of Dentistry, 1992, p574)

Research Excerpts

ExcerptRelevanceReference
"The study aims to determine the prevalence and severity of gingival overgrowth in a group of adult organ transplant recipients immunosuppressed with tacrolimus in comparison with ciclosporin, and to examine various risk factors for the development of gingival overgrowth."7.72Prevalence of gingival overgrowth in transplant patients immunosuppressed with tacrolimus. ( Ellis, JS; Seymour, RA; Taylor, JJ; Thomason, JM, 2004)
"The purpose of the study was to compare mitotic activity in the basal cell layer of normal human gingiva and in nifedipine- and immunosuppressive medication-induced gingival overgrowth."7.71Mitotic activity of keratinocytes in nifedipine- and immunosuppressive medication-induced gingival overgrowth. ( Knuuttila, ML; Nurmenniemi, PK; Pernu, HE, 2001)
"The purpose of this study was to compare the distribution of Langerhans' cells in normal human gingiva and in nifedipine- and immunosuppressive medication-induced gingival overgrowth by means of an immunohistochemical study."7.70Density of CD1a-labeled Langerhans' cells in normal human gingiva and in nifedipine- and immunosuppressive medication-induced gingival overgrowth. ( Knuuttila, ML; Nurmenniemi, PK; Pernu, HE, 1999)
"In the absence of calcium channel blockers, this study showed that pharmacologic variables, such as cyclosporin serum concentration, prednisolone and azathioprine dosages, and time since transplant, are strongly related to gingival overgrowth."3.74Demographic, pharmacologic, and periodontal variables for gingival overgrowth in subjects medicated with cyclosporin in the absence of calcium channel blockers. ( Costa, JE; Cota, LO; Ferreira, SD; Lages, EJ; Oliveira Costa, F; Oliveira, AM, 2007)
"The study aims to determine the prevalence and severity of gingival overgrowth in a group of adult organ transplant recipients immunosuppressed with tacrolimus in comparison with ciclosporin, and to examine various risk factors for the development of gingival overgrowth."3.72Prevalence of gingival overgrowth in transplant patients immunosuppressed with tacrolimus. ( Ellis, JS; Seymour, RA; Taylor, JJ; Thomason, JM, 2004)
"The purpose of the study was to compare mitotic activity in the basal cell layer of normal human gingiva and in nifedipine- and immunosuppressive medication-induced gingival overgrowth."3.71Mitotic activity of keratinocytes in nifedipine- and immunosuppressive medication-induced gingival overgrowth. ( Knuuttila, ML; Nurmenniemi, PK; Pernu, HE, 2001)
"The purpose of this study was to compare the distribution of Langerhans' cells in normal human gingiva and in nifedipine- and immunosuppressive medication-induced gingival overgrowth by means of an immunohistochemical study."3.70Density of CD1a-labeled Langerhans' cells in normal human gingiva and in nifedipine- and immunosuppressive medication-induced gingival overgrowth. ( Knuuttila, ML; Nurmenniemi, PK; Pernu, HE, 1999)
"Univariate analysis identified the duration of transplant, papilla bleeding index, creatinine serum concentration, azathioprine and prednisolone dosage as risk factors for overgrowth severity."1.33Risk factors for gingival overgrowth in patients medicated with ciclosporin in the absence of calcium channel blockers. ( Ellis, JS; Seymour, RA; Thomason, JM, 2005)
" Duration of treatment, dosage of drugs per kg body weight and serum cyclosporin levels were recorded."1.30Contribution of individual drugs to gingival overgrowth in adult and juvenile renal transplant patients treated with multiple therapy. ( Ashley, FP; Koffman, CG; Morel, A; Ogg, CS; Rigden, SP; Smith, D; Wilson, RF, 1998)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's4 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ellis, JS2
Seymour, RA2
Taylor, JJ1
Thomason, JM2
Oliveira Costa, F1
Ferreira, SD1
Lages, EJ1
Costa, JE1
Oliveira, AM1
Cota, LO1
Wilson, RF1
Morel, A1
Smith, D1
Koffman, CG1
Ogg, CS1
Rigden, SP1
Ashley, FP1
Nurmenniemi, PK2
Pernu, HE2
Knuuttila, ML2

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Genes Associated With Hereditary and Drug-Induced Gingival Overgrowth[NCT00104026]45 participants (Actual)Observational2005-02-15Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

6 other studies available for prednisolone and Gingival Overgrowth

ArticleYear
Prevalence of gingival overgrowth in transplant patients immunosuppressed with tacrolimus.
    Journal of clinical periodontology, 2004, Volume: 31, Issue:2

    Topics: Adolescent; Adult; Aged; Azathioprine; Calcium Channel Blockers; Chi-Square Distribution; Cyclospori

2004
Risk factors for gingival overgrowth in patients medicated with ciclosporin in the absence of calcium channel blockers.
    Journal of clinical periodontology, 2005, Volume: 32, Issue:3

    Topics: Anti-Inflammatory Agents; Azathioprine; Body Weight; Creatinine; Cyclosporine; Dental Plaque Index;

2005
Demographic, pharmacologic, and periodontal variables for gingival overgrowth in subjects medicated with cyclosporin in the absence of calcium channel blockers.
    Journal of periodontology, 2007, Volume: 78, Issue:2

    Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Calcium Channel Blockers; Chi-Square Distribution; Cy

2007
Contribution of individual drugs to gingival overgrowth in adult and juvenile renal transplant patients treated with multiple therapy.
    Journal of clinical periodontology, 1998, Volume: 25, Issue:6

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Azathioprine; Body We

1998
Density of CD1a-labeled Langerhans' cells in normal human gingiva and in nifedipine- and immunosuppressive medication-induced gingival overgrowth.
    Journal of periodontology, 1999, Volume: 70, Issue:7

    Topics: Adult; Anti-Inflammatory Agents; Antigens, CD1; Azathioprine; Calcium Channel Blockers; Cell Count;

1999
Mitotic activity of keratinocytes in nifedipine- and immunosuppressive medication-induced gingival overgrowth.
    Journal of periodontology, 2001, Volume: 72, Issue:2

    Topics: Adult; Aged; Azathioprine; Calcium Channel Blockers; Cell Count; Cyclosporine; Epithelial Cells; Epi

2001