prednisolone has been researched along with Fuchs' Endothelial Dystrophy in 9 studies
Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.
Fuchs' Endothelial Dystrophy: Disorder caused by loss of endothelium of the central cornea. It is characterized by hyaline endothelial outgrowths on Descemet's membrane, epithelial blisters, reduced vision, and pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Dosing was 4 times daily in months 1 to 3, thrice daily in month 4, twice daily in month 5, and once daily in months 6 to 12." | 2.79 | Randomized comparison of topical prednisolone acetate 1% versus fluorometholone 0.1% in the first year after descemet membrane endothelial keratoplasty. ( Bachmann, BO; Kruse, FE; Price, FW; Price, MO; Tourtas, T, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tourtas, T | 2 |
| Schlomberg, J | 1 |
| Wessel, JM | 1 |
| Bachmann, BO | 2 |
| Schlötzer-Schrehardt, U | 1 |
| Kruse, FE | 2 |
| Hos, D | 1 |
| Heindl, LM | 1 |
| Bucher, F | 1 |
| Cursiefen, C | 1 |
| Price, MO | 2 |
| Price, FW | 2 |
| Scanameo, A | 1 |
| Feng, MT | 1 |
| Bronner, A | 1 |
| Erdurmus, M | 1 |
| Cohen, EJ | 1 |
| Yildiz, EH | 1 |
| Hammersmith, KM | 1 |
| Laibson, PR | 1 |
| Varssano, D | 1 |
| Rapuano, CJ | 1 |
| Li, JY | 1 |
| Terry, MA | 1 |
| Goshe, J | 1 |
| Shamie, N | 1 |
| Davis-Boozer, D | 1 |
| Hjortdal, J | 1 |
| Pedersen, IB | 1 |
| Bak-Nielsen, S | 1 |
| Ivarsen, A | 1 |
| Driebe, WT | 1 |
| Park, JY | 1 |
| Meisler, DM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prospective Analysis of Loteprednol Etabonate Ophthalmic Suspension 0.25% for Prevention of Immunologic Rejection After Descemet Membrane Endothelial Keratoplasty[NCT05136443] | Phase 4 | 71 participants (Actual) | Interventional | 2021-11-23 | Completed | ||
| Comparison Of Two Corticosteroid Dosing Regimens For Prevention Of Corneal Transplant Rejection Episodes After Descemet's Membrane Endothelial Keratoplasty[NCT01448213] | Phase 2 | 264 participants (Actual) | Interventional | 2011-10-31 | Completed | ||
| Assessing eFficacy and Safety of DEXTENZA 0.4 mg inseRt in Conjunction With Topical Prednisolone Acetate 1% Treating Pain, and inflamMation Following Corneal Transplant Surgery Compared to Topical Prednisolone Acetate 1%.[NCT04521140] | Phase 4 | 36 participants (Actual) | Interventional | 2020-10-16 | Completed | ||
| Open-enrollment, Prospective Study of Endothelial Keratoplasty Outcomes[NCT00800111] | 2,593 participants (Actual) | Interventional | 2008-02-29 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT01448213)
Timeframe: Within 1 year
| Intervention | eyes (Number) |
|---|---|
| Fluorometholone 0.1% Solution | 2 |
| Prednisolone Acetate 1% Solution | 0 |
Absolute IOP greater than or equal to 24 mm Hg or a relative increase of 10 mm Hg over the baseline preoperative reading. (NCT01448213)
Timeframe: one day, two days, one week, one month, 3 months, 6 months and 12 months after DMEK
| Intervention | eyes (Number) |
|---|---|
| Fluorometholone 0.1% Solution | 9 |
| Prednisolone Acetate 1% Solution | 32 |
1 trial available for prednisolone and Fuchs' Endothelial Dystrophy
8 other studies available for prednisolone and Fuchs' Endothelial Dystrophy
| Article | Year |
|---|---|
Graft adhesion in descemet membrane endothelial keratoplasty dependent on size of removal of host's descemet membrane.
Topics: Aged; Aged, 80 and over; Corneal Stroma; Descemet Membrane; Descemet Stripping Endothelial Keratopla | 2014 |
Evidence of donor corneal endothelial cell migration from immune reactions occurring after descemet membrane endothelial keratoplasty.
Topics: Aged; Aged, 80 and over; Cell Count; Cell Movement; Descemet Stripping Endothelial Keratoplasty; End | 2014 |
Descemet's Membrane Endothelial Keratoplasty: Risk of Immunologic Rejection Episodes after Discontinuing Topical Corticosteroids.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Cell Count; Corneal Endothelial Cell Loss; | 2016 |
Descemet's Membrane Endothelial Keratoplasty: Risk of Immunologic Rejection Episodes after Discontinuing Topical Corticosteroids.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Cell Count; Corneal Endothelial Cell Loss; | 2016 |
Descemet's Membrane Endothelial Keratoplasty: Risk of Immunologic Rejection Episodes after Discontinuing Topical Corticosteroids.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Cell Count; Corneal Endothelial Cell Loss; | 2016 |
Descemet's Membrane Endothelial Keratoplasty: Risk of Immunologic Rejection Episodes after Discontinuing Topical Corticosteroids.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Cell Count; Corneal Endothelial Cell Loss; | 2016 |
Descemet's stripping automated endothelial keratoplasty.
Topics: Aged; Aged, 80 and over; Corneal Edema; Corneal Transplantation; Descemet Membrane; Endothelium, Cor | 2008 |
Steroid-induced intraocular pressure elevation or glaucoma after penetrating keratoplasty in patients with keratoconus or Fuchs dystrophy.
Topics: Adolescent; Adult; Aged; Androstadienes; Female; Fluorometholone; Fuchs' Endothelial Dystrophy; Glau | 2009 |
Graft rejection after Descemet's stripping automated endothelial keratoplasty: graft survival and endothelial cell loss.
Topics: Aged; Cell Count; Corneal Endothelial Cell Loss; Descemet Stripping Endothelial Keratoplasty; Endoth | 2012 |
Graft rejection and graft failure after penetrating keratoplasty or posterior lamellar keratoplasty for fuchs endothelial dystrophy.
Topics: Aged; Aged, 80 and over; Chloramphenicol; Corneal Transplantation; Descemet Stripping Endothelial Ke | 2013 |
Epithelial rejection rings.
Topics: Administration, Topical; Aged; Aged, 80 and over; Cornea; Corneal Diseases; Corneal Transplantation; | 1997 |