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prednisolone and Fracture, Pathologic

prednisolone has been researched along with Fracture, Pathologic in 21 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Research Excerpts

ExcerptRelevanceReference
"Treatment with lenalidomide, as the final therapeutic option, resolved the intractable melena and improved both the intestinal lesions and myeloma."5.39Therapeutic effects of lenalidomide on hemorrhagic intestinal myeloma-associated AL amyloidosis. ( Aoki, K; Arima, H; Imai, H; Ishikawa, T; Kato, A; Matsushita, A; Mori, M; Nagano, S; Ono, Y; Tabata, S; Takahashi, T; Takiuchi, Y; Yanagita, S, 2013)
"We report a rare case of ulcerative colitis (UC) associated with methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa infections in multiple organs, and with compressive fracture from osteoporosis after the administration of high-dose prednisolone and azathioprine."3.70Severe complications of ulcerative colitis after high-dose prednisolone and azathioprine treatment. ( Abo, Y; Kawamura, YJ; Masaki, T; Matsuda, K; Muto, T; Uchida, H; Watanabe, T, 1999)
"Steroid-induced osteoporosis has been reported to show reduced osteoblastic bone formation and accelerated osteoclastic bone resorption."2.44[Assessment of bone quality. Bone quality of steroid-induced osteoporosis]. ( Amizuka, N; Li, M; Saito, T, 2008)
"Treatment with lenalidomide, as the final therapeutic option, resolved the intractable melena and improved both the intestinal lesions and myeloma."1.39Therapeutic effects of lenalidomide on hemorrhagic intestinal myeloma-associated AL amyloidosis. ( Aoki, K; Arima, H; Imai, H; Ishikawa, T; Kato, A; Matsushita, A; Mori, M; Nagano, S; Ono, Y; Tabata, S; Takahashi, T; Takiuchi, Y; Yanagita, S, 2013)
"In our case, senile osteoporosis was present before the onset of the fracture was recognized on radiographs, and RA and corticosteroid therapy might have further aggravated the porosis, resulting in the destruction of the fossa acetabuli."1.31A case report of insufficiency fracture of the Fossa acetabuli in a patient with rheumatoid arthritis. ( Nakayama, Y; Ozaki, D; Shirai, Y; Uesaka, S, 2000)
" The dosage of the steroid, life style factors, menopausal status, low bone mineral density at baseline and previous osteoporotic fractures predispose for the manifestation of steroid-induced osteoporosis."1.31[Risk of osteoporosis in steroid therapy. When and how to counter the risk]. ( Aschl, G; Hinterreiter, M; Kirchgatterer, A; Knoflach, P, 2001)
" The dosage of 4."1.25On the effect of prednisolone on hamster bone. ( Bühler, G; Lindenhayn, K; Mühlbach, R, 1975)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19905 (23.81)18.7374
1990's4 (19.05)18.2507
2000's7 (33.33)29.6817
2010's5 (23.81)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nagano, S1
Mori, M1
Kato, A1
Ono, Y1
Aoki, K1
Arima, H1
Takiuchi, Y1
Tabata, S1
Yanagita, S1
Matsushita, A1
Ishikawa, T1
Imai, H1
Takahashi, T1
Wong, SC1
Catto-Smith, AG1
Zacharin, M1
Suzuki, Y1
Houssaini, GS1
Tahiri, L1
Ibrahimi, A1
Tizniti, S1
Elmrini, A1
Harzy, T1
Nguyen, M1
Peschken, CA1
Murakami, Y1
Yamanouchi, J1
Azuma, T1
Ikeda, Y1
Narumi, H1
Fujiwara, H1
Yakushijin, Y1
Hato, T1
Yasukawa, M1
AMANN, E1
SALEM, G1
Yamamoto, Y1
Ishii, K1
Nomura, S1
Fukuhara, S1
Dreher, R1
Buttgereit, F1
Demary, W1
Görtz, B1
Hein, G1
Kern, P1
Schulz, A1
Li, M1
Saito, T1
Amizuka, N1
Venkatachalam, S1
Balakrishnan, C1
Mangat, G1
Deshpande, RB1
Chinoy, R1
Joshi, VR1
Bijlsma, JW1
Elstein, D1
Abrahamov, A1
Itzchaki, M1
Zimran, A1
Matsuda, K1
Watanabe, T1
Abo, Y1
Uchida, H1
Kawamura, YJ1
Masaki, T1
Muto, T1
Ozaki, D1
Shirai, Y1
Nakayama, Y1
Uesaka, S1
Sambrook, P1
Raj, A1
Hunter, D1
Naganathan, V1
Mason, R1
Robinson, B1
Kirchgatterer, A1
Aschl, G1
Hinterreiter, M1
Knoflach, P1
Matsuo, H1
Matsuo, T1
Lindenhayn, K1
Bühler, G1
Mühlbach, R1
Takeo, Y1
Tominaga, K1
Tsuji, H1
Yoh, K1
Nakano, K1
Möller, E1
Brinkmann, W1
Weber, O1
Wildhirt, E1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Bone Density in Children With IBD Treated With Amorphous Calcium or Commercial Crystalline Calcium: A Prospective Randomized Multicenter Trial[NCT02470663]0 participants (Actual)Interventional2015-07-31Withdrawn (stopped due to company and Sheba did not reach an agreement)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for prednisolone and Fracture, Pathologic

ArticleYear
Pathological fractures in paediatric patients with inflammatory bowel disease.
    European journal of pediatrics, 2014, Volume: 173, Issue:2

    Topics: Adolescent; Body Height; Body Weight; Bone Density; Child; Colitis, Ulcerative; Crohn Disease; Dipho

2014
[Current topics over updating guidelines on the management and treatment of glucocorticoid-induced osteoporosis].
    Clinical calcium, 2014, Volume: 24, Issue:3

    Topics: Bone Density Conservation Agents; Diphosphonates; Evidence-Based Medicine; Fractures, Spontaneous; G

2014
Severe Sensory Neuronopathy in Primary Sjögren Syndrome Resulting in Charcot Arthropathy.
    The Journal of rheumatology, 2016, Volume: 43, Issue:7

    Topics: Aged; Ankle Fractures; Arthropathy, Neurogenic; Electromyography; Female; Follow-Up Studies; Fractur

2016
[Primary osseous lymphoma with pathological fracture during therapy].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2009, Volume: 50, Issue:3

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemot

2009
[Assessment of bone quality. Bone quality of steroid-induced osteoporosis].
    Clinical calcium, 2008, Volume: 18, Issue:3

    Topics: Apoptosis; Bone and Bones; Bone Density; Bone Resorption; Fractures, Spontaneous; Glucocorticoids; H

2008

Trials

1 trial available for prednisolone and Fracture, Pathologic

ArticleYear
Osteoporosis with low dose corticosteroids: contribution of underlying disease effects and discriminatory ability of ultrasound versus bone densitometry.
    The Journal of rheumatology, 2001, Volume: 28, Issue:5

    Topics: Absorptiometry, Photon; Bone Density; Female; Fractures, Spontaneous; Glucocorticoids; Humans; Male;

2001

Other Studies

15 other studies available for prednisolone and Fracture, Pathologic

ArticleYear
Therapeutic effects of lenalidomide on hemorrhagic intestinal myeloma-associated AL amyloidosis.
    Internal medicine (Tokyo, Japan), 2013, Volume: 52, Issue:10

    Topics: Aged; Amyloid; Amyloidosis; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols;

2013
Bone lymphoma revealed by cruralgia during pregnancy: a case report.
    The Pan African medical journal, 2014, Volume: 18

    Topics: Abortion, Therapeutic; Adult; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemot

2014
[SPONTANEOUS FRACTURES OF THE FEMORAL NECK DURING CORTICOID THERAPY].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1964, Volume: 35

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Femoral Neck Fractures; Femur Neck; Fractures,

1964
[Adult T-cell leukemia/lymphoma of bone with multiple pathological fractures].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2004, Volume: 45, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cyclophosphamide; Doxorubicin; Etoposid

2004
[Insufficiency fractures in rheumatology. Case report and overview].
    Zeitschrift fur Rheumatologie, 2006, Volume: 65, Issue:5

    Topics: Aged; Arthritis, Rheumatoid; Biopsy; Bone and Bones; Chronic Kidney Disease-Mineral and Bone Disorde

2006
Destructive bone lesion in primary amyloidosis.
    The Journal of the Association of Physicians of India, 1996, Volume: 44, Issue:5

    Topics: Adult; Amyloidosis; Bone Diseases; Colchicine; Diagnosis, Differential; Drug Therapy, Combination; F

1996
Prevention of glucocorticoid induced osteoporosis.
    Annals of the rheumatic diseases, 1997, Volume: 56, Issue:9

    Topics: Bone Density; Calcium; Fractures, Spontaneous; Glucocorticoids; Humans; Osteoporosis; Prednisolone;

1997
Commentary: low-dose high-frequency enzyme replacement therapy prevents fractures without complete suppression of painful bone crises in patients with severe juvenile onset type I Gaucher disease.
    Blood cells, molecules & diseases, 1998, Volume: 24, Issue:3

    Topics: Adolescent; Adult; Age Factors; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Ste

1998
Severe complications of ulcerative colitis after high-dose prednisolone and azathioprine treatment.
    Journal of gastroenterology, 1999, Volume: 34, Issue:3

    Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Colitis, Ulcerative; Colonoscopy; Dose-Response Relat

1999
A case report of insufficiency fracture of the Fossa acetabuli in a patient with rheumatoid arthritis.
    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2000, Volume: 67, Issue:4

    Topics: Acetabulum; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Arthroplasty, Replacement, Hip; F

2000
[Risk of osteoporosis in steroid therapy. When and how to counter the risk].
    MMW Fortschritte der Medizin, 2001, Jun-21, Volume: 143, Issue:25

    Topics: Anti-Inflammatory Agents; Bone Density; Dose-Response Relationship, Drug; Female; Fractures, Spontan

2001
[The compression fracture of the vertebral bodies in patients with rheumatoid arthritis (author's transl)].
    Ryumachi. [Rheumatism], 1979, Volume: 19, Issue:4

    Topics: Adult; Arthritis, Rheumatoid; Female; Fractures, Spontaneous; Humans; Lumbar Vertebrae; Male; Middle

1979
On the effect of prednisolone on hamster bone.
    Experimentelle Pathologie, 1975, Volume: 11, Issue:1-2

    Topics: Animals; Bone and Bones; Cricetinae; Elasticity; Femur; Fractures, Spontaneous; Osteoporosis; Predni

1975
[Spontaneous fracture and osteoporosis following renal transplantation].
    Nihon Seikeigeka Gakkai zasshi, 1989, Volume: 63, Issue:5

    Topics: Adolescent; Adult; Bone and Bones; Child; Child, Preschool; Female; Fractures, Spontaneous; Humans;

1989
[Side-effects of glucocorticoids in liver therapy].
    Deutsche medizinische Wochenschrift (1946), 1969, Jun-27, Volume: 94, Issue:26

    Topics: Acute Disease; Chronic Disease; Diabetes Mellitus; Fractures, Spontaneous; Glucocorticoids; Hepatiti

1969