Page last updated: 2024-11-06

prednisolone and Erysipelas

prednisolone has been researched along with Erysipelas in 5 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Erysipelas: An acute infection of the skin caused by species of STREPTOCOCCUS. This disease most frequently affects infants, young children, and the elderly. Characteristics include pink-to-red lesions that spread rapidly and are warm to the touch. The commonest site of involvement is the face.

Research Excerpts

ExcerptRelevanceReference
"112 patients admitted to hospital with a diagnosis of erysipelas, were randomized to 8 days treatment with prednisolone or placebo in addition to antibiotics."9.08Antibiotic and prednisolone therapy of erysipelas: a randomized, double blind, placebo-controlled study. ( Bergkvist, PI; Sjöbeck, K, 1997)
"Of 112 patients with erysipelas, who were randomized to treatment with 8 d of either prednisolone or placebo in addition to antibiotics, 103 were followed-up for 12 months after they had been cured."9.08Relapse of erysipelas following treatment with prednisolone or placebo in addition to antibiotics: a 1-year follow-up. ( Bergkvist, PI; Sjöbeck, K, 1998)
"112 patients admitted to hospital with a diagnosis of erysipelas, were randomized to 8 days treatment with prednisolone or placebo in addition to antibiotics."5.08Antibiotic and prednisolone therapy of erysipelas: a randomized, double blind, placebo-controlled study. ( Bergkvist, PI; Sjöbeck, K, 1997)
"Of 112 patients with erysipelas, who were randomized to treatment with 8 d of either prednisolone or placebo in addition to antibiotics, 103 were followed-up for 12 months after they had been cured."5.08Relapse of erysipelas following treatment with prednisolone or placebo in addition to antibiotics: a 1-year follow-up. ( Bergkvist, PI; Sjöbeck, K, 1998)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's2 (40.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Krumbholz, A1
Heinemann, C1
Ziemer, M1
Schreiber, G1
Abendroth, B1
Preussat, K1
Peter, E1
Bergkvist, PI2
Sjöbeck, K2
Cherkasov, VL1
Schuhmachers, R1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Use of Corticosteroids in Children Hospitalized With Cellulitis: Randomized, Double Blind, Placebo Controlled Trial[NCT02087527]19 participants (Actual)Interventional2014-06-30Terminated (stopped due to Calculated sample size not achieved)
Use of a Single Dose of Oral Prednisone in the Treatment of Cellulitis[NCT01671423]42 participants (Actual)Interventional2012-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Amount of Pain Medication - Day 1 to 48 Hours

Number of times the subject needed to use pain medication between day 1 and the 48 hour follow-up (NCT01671423)
Timeframe: Assessed once during the 48 hour follow-up

Interventionmedications taken (Median)
Prednisone7
Placebo2

Visual Analog Scale(VAS) for Pain - Day 1 to 48 Hours

The level of pain as measured by a Visual Analog Scale(VAS) measured once at day 1 and once during the 48th hour follow-up visit. Minimum value 0, maximum value 100mm, higher scores corresponds to more pain/worse outcomes. (NCT01671423)
Timeframe: Assessed once at day 1 and then once during the 48 hour follow-up

,
Interventionscore on a scale (Mean)
VAS at Day 1VAS at 48 hrs
Placebo56.4525.91
Prednisone79.6439.71

Trials

2 trials available for prednisolone and Erysipelas

ArticleYear
Antibiotic and prednisolone therapy of erysipelas: a randomized, double blind, placebo-controlled study.
    Scandinavian journal of infectious diseases, 1997, Volume: 29, Issue:4

    Topics: Anti-Inflammatory Agents; Bacteremia; Double-Blind Method; Drug Therapy, Combination; Erysipelas; Fe

1997
Antibiotic and prednisolone therapy of erysipelas: a randomized, double blind, placebo-controlled study.
    Scandinavian journal of infectious diseases, 1997, Volume: 29, Issue:4

    Topics: Anti-Inflammatory Agents; Bacteremia; Double-Blind Method; Drug Therapy, Combination; Erysipelas; Fe

1997
Antibiotic and prednisolone therapy of erysipelas: a randomized, double blind, placebo-controlled study.
    Scandinavian journal of infectious diseases, 1997, Volume: 29, Issue:4

    Topics: Anti-Inflammatory Agents; Bacteremia; Double-Blind Method; Drug Therapy, Combination; Erysipelas; Fe

1997
Antibiotic and prednisolone therapy of erysipelas: a randomized, double blind, placebo-controlled study.
    Scandinavian journal of infectious diseases, 1997, Volume: 29, Issue:4

    Topics: Anti-Inflammatory Agents; Bacteremia; Double-Blind Method; Drug Therapy, Combination; Erysipelas; Fe

1997
Relapse of erysipelas following treatment with prednisolone or placebo in addition to antibiotics: a 1-year follow-up.
    Scandinavian journal of infectious diseases, 1998, Volume: 30, Issue:2

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Drug Therapy, Combination; Erysipelas; Follow-Up St

1998

Other Studies

3 other studies available for prednisolone and Erysipelas

ArticleYear
[Relapsing polychondritis as a rare different diagnosis of erysipelas].
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2004, Volume: 2, Issue:4

    Topics: Aged; Anti-Inflammatory Agents; Diagnosis, Differential; Ear Diseases; Erysipelas; Female; Humans; P

2004
[Current methods of treating patients with erysipelas].
    Klinicheskaia meditsina, 1972, Volume: 50, Issue:3

    Topics: Anti-Bacterial Agents; Erysipelas; Humans; Penicillins; Prednisolone; Prodigiosin; Recurrence; Strep

1972
[Effect and side-effects of plastic injections].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1965, Volume: 16, Issue:10

    Topics: Aged; Animals; Breast; Cosmetics; Erysipelas; Face; Female; Granuloma; Humans; Injections, Intraderm

1965