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prednisolone and Delayed Effects, Prenatal Exposure

prednisolone has been researched along with Delayed Effects, Prenatal Exposure in 12 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Research Excerpts

ExcerptRelevanceReference
"In this retrospective case series, we found no evidence of prolonged effects of maternal prednisolone use during pregnancy on the neonatal hypothalamic-pituitary-adrenal axis."3.85Maternal use of prednisolone is unlikely to be associated with neonatal adrenal suppression-a single-center study of 16 cases. ( Bocca, G; de Vetten, L; Kema, IP; van Stuijvenberg, M, 2017)
"Prednisolone is widely used to treat medical conditions in pregnancy, despite the lack of long-term safety studies on infants."3.72Infant cortisol response after prolonged antenatal prednisolone treatment. ( Fisk, NM; Glover, V; Miller, NM; Williamson, C, 2004)
"The influence of prenatal exposure to the synthetic glucocorticoid prednisolone (PRED) was examined in female offspring of mice administered the drug on Days 13-18 of pregnancy."3.66Deleterious effects of prenatal prednisolone exposure upon morphological and behavioral development of mice. ( Gandelman, R; Rosenthal, C, 1981)
"83 prednisolone-treated and 57 control children of a previous study demonstrating benefits of antenatal steroid prophylaxis of IRDS were reexamined at the age of 6 years."1.27Normal physical and mental development of 6-year-old children whose mothers were treated antenatally with prednisolone. ( Adamovich, K; Arató, J; Horváth, I; Ostorharics-Horváth, G; Papp, K, 1984)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19903 (25.00)18.7374
1990's4 (33.33)18.2507
2000's2 (16.67)29.6817
2010's2 (16.67)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Kieffer, TE1
Chin, PY1
Green, ES1
Moldenhauer, LM1
Prins, JR1
Robertson, SA1
de Vetten, L1
van Stuijvenberg, M1
Kema, IP1
Bocca, G1
Shimizu, M1
Sakakibara, Y1
Kawano, M1
Yachie, A1
Miller, NM1
Williamson, C1
Fisk, NM1
Glover, V1
Ducray, F1
Colin, P1
Cartalat-Carel, S1
Pelissou-Guyotat, I1
Mahla, K1
Audra, P1
Gaucherand, P1
Honnorat, J1
Trouillas, P1
Horváth, I2
Adamovich, K2
Arató, J2
Ostorharics-Horváth, G2
Papp, K2
Gandelman, R1
Rosenthal, C1
Rink, T1
Wieg, C1
Schroth, HJ1
Helisch, A1
Bertram, U1
Taniguchi, H2
Yoshitomi, H1
Miyazaki, K1
Koga, N1
Himeno, Y2
Hara, Y1
Nakamura, M2
Tsuji, M2
Tanaka, H3
Shinomiya, M3
Chono, M1
Araki, E1
Aso, S1
Morita, S1
Kajiwara, Y1
Horiwaki, S1

Other Studies

12 other studies available for prednisolone and Delayed Effects, Prenatal Exposure

ArticleYear
Prednisolone in early pregnancy inhibits regulatory T cell generation and alters fetal and placental development in mice.
    Molecular human reproduction, 2020, 05-15, Volume: 26, Issue:5

    Topics: Animals; Cell Differentiation; Female; Fetal Development; Fetus; Gestational Age; Lymphopoiesis; Mal

2020
Maternal use of prednisolone is unlikely to be associated with neonatal adrenal suppression-a single-center study of 16 cases.
    European journal of pediatrics, 2017, Volume: 176, Issue:8

    Topics: Adrenal Insufficiency; Female; Follow-Up Studies; Glucocorticoids; Humans; Hypoglycemia; Hypothalamo

2017
Transient impairment of NK cell function in an infant born to a mother with adult-onset Still's disease: perinatal effect of maternal IL-18.
    Clinical immunology (Orlando, Fla.), 2012, Volume: 143, Issue:3

    Topics: Adult; Cyclosporine; Etanercept; Female; Humans; Immunoglobulin G; Immunosuppressive Agents; Infant,

2012
Infant cortisol response after prolonged antenatal prednisolone treatment.
    BJOG : an international journal of obstetrics and gynaecology, 2004, Volume: 111, Issue:12

    Topics: Adult; Cohort Studies; Crying; Female; Humans; Hydrocortisone; Infant; Mother-Child Relations; Predn

2004
[Management of malignant gliomas diagnosed during pregnancy].
    Revue neurologique, 2006, Volume: 162, Issue:3

    Topics: Abortion, Therapeutic; Adrenal Cortex Hormones; Adult; Algorithms; Anesthesia, General; Antineoplast

2006
[Follow-up studies on 6-year-old children of mothers having previously undergone preventive steroid therapy].
    Orvosi hetilap, 1984, Jul-22, Volume: 125, Issue:30

    Topics: Abnormalities, Drug-Induced; Child; Developmental Disabilities; Female; Follow-Up Studies; Humans; M

1984
Normal physical and mental development of 6-year-old children whose mothers were treated antenatally with prednisolone.
    Acta paediatrica Hungarica, 1984, Volume: 25, Issue:4

    Topics: Child; Child Development; Female; Humans; Infant, Newborn; Intelligence; Male; Mental Processes; Pre

1984
Deleterious effects of prenatal prednisolone exposure upon morphological and behavioral development of mice.
    Teratology, 1981, Volume: 24, Issue:3

    Topics: Animals; Behavior, Animal; Body Weight; Dose-Response Relationship, Drug; Drug Interactions; Ethamox

1981
[Hyperthyroidism in a premature infant due to transplacental passage of maternal thyrotropin receptor antibodies].
    Nuklearmedizin. Nuclear medicine, 1999, Volume: 38, Issue:5

    Topics: Adult; Anti-Arrhythmia Agents; Antithyroid Agents; Autoantibodies; Carbimazole; Cardiotonic Agents;

1999
[Reproductive and developmental toxicity study of prednisolone farnesylate (PNF)--study by subcutaneous administration of PNF prior to and in the early stages of pregnancy in rats].
    The Journal of toxicological sciences, 1992, Volume: 17 Suppl 3

    Topics: Animals; Body Weight; Embryonic and Fetal Development; Farnesol; Female; Fetus; Injections, Subcutan

1992
[Reproductive and developmental toxicity study of prednisolone farnesylate (PNF)--study by subcutaneous administration of PNF during the period of fetal organogenesis in rats].
    The Journal of toxicological sciences, 1992, Volume: 17 Suppl 3

    Topics: Animals; Behavior, Animal; Body Weight; Embryonic and Fetal Development; Farnesol; Female; Fetus; In

1992
[Reproductive and developmental toxicity study of prednisolone farnesylate (PNF)--teratogenicity study in rabbits by subcutaneous administration].
    The Journal of toxicological sciences, 1992, Volume: 17 Suppl 3

    Topics: Animals; Body Weight; Embryonic and Fetal Development; Farnesol; Female; Fetus; Injections, Subcutan

1992