prednisolone has been researched along with Cystic Fibrosis in 33 studies
Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.
Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of oral prednisolone on the lung function of 20 adult patients with cystic fibrosis who had severe stable airflow obstruction was assessed in a placebo controlled study, blind to the patients." | 9.06 | Prednisolone in the treatment of airflow obstruction in adults with cystic fibrosis. ( Batten, JC; Hodson, ME; Pantin, CF; Stead, RJ, 1986) |
| "Prednisolone pharmacokinetics were evaluated in eight patients with cystic fibrosis (CF) (aged 1." | 7.68 | Altered prednisolone pharmacokinetics in patients with cystic fibrosis. ( Accurso, FJ; Dove, AM; Hill, MR; Jusko, WJ; Larsen, GL; Szefler, SJ, 1992) |
| "Prednisolone was administered, in a double blind and placebo controlled manner, at an initial dose of 2 mg/kg daily for 14 days and tapered to 1 mg/kg on alternate days for 10 weeks." | 6.67 | Interleukin-1 alpha, soluble interleukin-2 receptor, and IgG concentrations in cystic fibrosis treated with prednisolone. ( Greally, P; Hussain, MJ; Price, JF; Vergani, D, 1994) |
| "The effect of oral prednisolone on the lung function of 20 adult patients with cystic fibrosis who had severe stable airflow obstruction was assessed in a placebo controlled study, blind to the patients." | 5.06 | Prednisolone in the treatment of airflow obstruction in adults with cystic fibrosis. ( Batten, JC; Hodson, ME; Pantin, CF; Stead, RJ, 1986) |
| "MODE OF ACTION OF URSODEOXYCHOLIC ACID: In cholestasis, the impaired biliary secretion of toxic bile acids causes their accumulation in the liver and a subsequent hepatic failure." | 4.81 | [Treatment of cholestatic liver diseases]. ( Gatzen, M; Pausch, J, 2002) |
| "Prednisolone pharmacokinetics were evaluated in eight patients with cystic fibrosis (CF) (aged 1." | 3.68 | Altered prednisolone pharmacokinetics in patients with cystic fibrosis. ( Accurso, FJ; Dove, AM; Hill, MR; Jusko, WJ; Larsen, GL; Szefler, SJ, 1992) |
| "The effect of intestinal malabsorption on the oral bioavailability of prednisolone has been studied in six patients with celiac disease and in six patients with malabsorption of various etiologies, five of whom had undergone gut resections." | 3.66 | Bioavailability of prednisolone in patients with intestinal malabsorption: the importance of measuring serum protein-binding. ( Bergrem, H; Opedal, I, 1983) |
| "Prednisolone was administered, in a double blind and placebo controlled manner, at an initial dose of 2 mg/kg daily for 14 days and tapered to 1 mg/kg on alternate days for 10 weeks." | 2.67 | Interleukin-1 alpha, soluble interleukin-2 receptor, and IgG concentrations in cystic fibrosis treated with prednisolone. ( Greally, P; Hussain, MJ; Price, JF; Vergani, D, 1994) |
| " The correlation of proximal muscle strength, but not HG strength, with steroid dosage further supports a cause-effect relationship." | 1.32 | Corticosteroids and skeletal muscle function in cystic fibrosis. ( Barry, SC; Gallagher, CG, 2003) |
| "This case suggests that bronchiolitis obliterans organizing pneumonia may be a distinct pulmonary complication in cystic fibrosis and improve with specific therapy." | 1.31 | Bronchiolitis obliterans organizing pneumonia: a distinct pulmonary complication in cystic fibrosis. ( Biesterfeld, S; Friedrichs, F; Häusler, M; Kentrup, H; Kusenbach, G; Meilicke, R, 2000) |
| "Allergic bronchopulmonary aspergillosis is a serious complication of cystic fibrosis and may be difficult to diagnose." | 1.29 | Rise in total IgE as an indicator of allergic bronchopulmonary aspergillosis in cystic fibrosis. ( Bush, A; Marchant, JL; Warner, JO, 1994) |
| "The authors report two cases of allergic bronchopulmonary aspergillosis complicating cystic fibrosis in adults: respectively an acute and an exacerbation stage." | 1.29 | [Allergic bronchopulmonary aspergillosis and cystic fibrosis. 2 case reports in adults]. ( Bildstein, F; Dalphin, JC; Debieuvre, D; Depierre, A; Estavoyer, JM; Leroy, J, 1993) |
| "We conclude that allergic bronchopulmonary aspergillosis is not uncommon in patients with cystic fibrosis." | 1.28 | Cystic fibrosis and allergic bronchopulmonary aspergillosis. ( Evans, EG; Littlewood, JM; Simmonds, EJ, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (24.24) | 18.7374 |
| 1990's | 10 (30.30) | 18.2507 |
| 2000's | 7 (21.21) | 29.6817 |
| 2010's | 8 (24.24) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, K | 3 |
| Ashby, D | 3 |
| Smyth, RL | 3 |
| Emiralioglu, N | 1 |
| Dogru, D | 1 |
| Tugcu, GD | 1 |
| Yalcin, E | 1 |
| Kiper, N | 1 |
| Ozcelik, U | 1 |
| Weckmann, M | 1 |
| Schultheiss, C | 1 |
| Hollaender, A | 1 |
| Bobis, I | 1 |
| Rupp, J | 1 |
| Kopp, MV | 1 |
| Snell, GI | 1 |
| Davis, AK | 1 |
| Menahem, S | 1 |
| Kotecha, S | 1 |
| Whitford, HM | 1 |
| Levvey, BJ | 1 |
| Paraskeva, M | 1 |
| Webb, A | 1 |
| Westall, GW | 1 |
| Walker, RG | 1 |
| Shmarina, G | 1 |
| Pukhalsky, A | 1 |
| Avakian, L | 1 |
| Semykin, S | 1 |
| Pukhalskaya, D | 1 |
| Alioshkin, V | 1 |
| Albersmeyer, MP | 1 |
| Hilge, RG | 1 |
| Schulze-Koops, H | 1 |
| Sitter, T | 1 |
| Skov, M | 1 |
| Høiby, N | 1 |
| Koch, C | 1 |
| Barry, SC | 1 |
| Gallagher, CG | 1 |
| Balfour-Lynn, IM | 1 |
| Mohan, U | 1 |
| Bush, A | 2 |
| Rosenthal, M | 1 |
| Burton, CM | 1 |
| Pressler, T | 1 |
| Milman, N | 1 |
| Bergrem, H | 1 |
| Opedal, I | 1 |
| Parameswaran, K | 1 |
| Keaney, NP | 1 |
| Veale, D | 1 |
| Marchant, JL | 1 |
| Warner, JO | 1 |
| Greally, P | 1 |
| Hussain, MJ | 1 |
| Vergani, D | 1 |
| Price, JF | 1 |
| Debieuvre, D | 1 |
| Dalphin, JC | 1 |
| Leroy, J | 1 |
| Estavoyer, JM | 1 |
| Bildstein, F | 1 |
| Depierre, A | 1 |
| Paul, KD | 1 |
| Leupold, W | 1 |
| Blaschke-Hellmessen, R | 1 |
| Ulbrich, K | 1 |
| Peter-Kern, M | 1 |
| Neumeister, V | 1 |
| Haworth, CS | 1 |
| Selby, PL | 1 |
| Webb, AK | 1 |
| Adams, JE | 1 |
| Freemont, TJ | 1 |
| Häusler, M | 1 |
| Meilicke, R | 1 |
| Biesterfeld, S | 1 |
| Kentrup, H | 1 |
| Friedrichs, F | 1 |
| Kusenbach, G | 1 |
| Linnane, SJ | 1 |
| Thin, AG | 1 |
| Keatings, VM | 1 |
| Moynihan, JB | 1 |
| McLoughlin, P | 1 |
| FitzGerald, MX | 1 |
| Gatzen, M | 1 |
| Pausch, J | 1 |
| Gibbons, A | 1 |
| Allan, JD | 1 |
| Holzel, A | 1 |
| McFarlane, H | 1 |
| Hiller, EJ | 2 |
| Dove, AM | 1 |
| Szefler, SJ | 1 |
| Hill, MR | 1 |
| Jusko, WJ | 1 |
| Larsen, GL | 1 |
| Accurso, FJ | 1 |
| Simmonds, EJ | 1 |
| Littlewood, JM | 2 |
| Evans, EG | 1 |
| Gilbert, J | 1 |
| Pantin, CF | 1 |
| Stead, RJ | 1 |
| Hodson, ME | 1 |
| Batten, JC | 1 |
| Phillips, BM | 1 |
| David, TJ | 1 |
| Goodchild, MC | 1 |
| Nelson, R | 1 |
| Anderson, CM | 1 |
| van Kruiningen, HJ | 1 |
| Williams, CB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Development; Feasibility/Safety and Validation of the Alfred Step Test Exercise Protocol (A-STEP) Developed for Adults With Cystic Fibrosis:[NCT02717650] | 30 participants (Anticipated) | Interventional | 2016-08-25 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for prednisolone and Cystic Fibrosis
| Article | Year |
|---|---|
Oral steroids for long-term use in cystic fibrosis.
Topics: Administration, Oral; Anti-Inflammatory Agents; Child; Cystic Fibrosis; Early Termination of Clinica | 2013 |
Oral steroids for long-term use in cystic fibrosis.
Topics: Administration, Oral; Anti-Inflammatory Agents; Child; Cystic Fibrosis; Early Termination of Clinica | 2015 |
Oral steroids for long-term use in cystic fibrosis.
Topics: Administration, Oral; Anti-Inflammatory Agents; Cystic Fibrosis; Glucocorticoids; Humans; Prednisolo | 2011 |
[Treatment of cholestatic liver diseases].
Topics: Adult; Age Factors; Anti-Inflammatory Agents; Azathioprine; Bile; Child; Cholagogues and Choleretics | 2002 |
Pathogenesis and management of aspergillosis in cystic fibrosis.
Topics: Aspergillosis, Allergic Bronchopulmonary; Cystic Fibrosis; Humans; Hypersensitivity, Immediate; Pred | 1990 |
Pathogenesis and management of arthropathy in cystic fibrosis.
Topics: Adolescent; Adult; Aspirin; Child; Child, Preschool; Cystic Fibrosis; Female; Humans; Joint Diseases | 1986 |
3 trials available for prednisolone and Cystic Fibrosis
| Article | Year |
|---|---|
Interleukin-1 alpha, soluble interleukin-2 receptor, and IgG concentrations in cystic fibrosis treated with prednisolone.
Topics: Adolescent; Adult; Child; Child, Preschool; Cystic Fibrosis; Double-Blind Method; Female; Forced Exp | 1994 |
Glucocorticoid treatment reduces exhaled nitric oxide in cystic fibrosis patients.
Topics: Adult; Breath Tests; Cross-Over Studies; Cystic Fibrosis; Double-Blind Method; Female; Humans; Lung | 2001 |
Prednisolone in the treatment of airflow obstruction in adults with cystic fibrosis.
Topics: Adolescent; Adult; Clinical Trials as Topic; Cystic Fibrosis; Female; Forced Expiratory Flow Rates; | 1986 |
24 other studies available for prednisolone and Cystic Fibrosis
| Article | Year |
|---|---|
Omalizumab Treatment for Allergic Bronchopulmonary Aspergillosis in Cystic Fibrosis.
Topics: Adolescent; Adult; Aspergillosis, Allergic Bronchopulmonary; Child; Cystic Fibrosis; Drug Therapy, C | 2016 |
Treatment with rhDNase in patients with cystic fibrosis alters in-vitro CHIT-1 activity of isolated leucocytes.
Topics: Adolescent; Adult; Aged; Albuterol; Aspergillus fumigatus; Azithromycin; Bacteria; Cystic Fibrosis; | 2016 |
ABO incompatible renal transplantation following lung transplantation.
Topics: ABO Blood-Group System; Acute Disease; Adult; Cystic Fibrosis; Disease-Free Survival; Female; Graft | 2016 |
Steady-State Therapy with Azithromycin or Low-Dose Prednisolone in Paediatric Cystic Fibrosis Patients: Inflammatory Markers and Disease Progression.
Topics: Adolescent; Adrenocorticotropic Hormone; Anti-Bacterial Agents; Anti-Inflammatory Agents; Azithromyc | 2017 |
Adult-onset Still's disease in a patient with cystic fibrosis and its successful treatment with anakinra.
Topics: Antirheumatic Agents; Cystic Fibrosis; Drug Therapy, Combination; Female; Glucocorticoids; Humans; I | 2012 |
Itraconazole treatment of allergic bronchopulmonary aspergillosis in patients with cystic fibrosis.
Topics: Antibodies, Fungal; Antifungal Agents; Aspergillosis, Allergic Bronchopulmonary; Aspergillus fumigat | 2002 |
Corticosteroids and skeletal muscle function in cystic fibrosis.
Topics: Administration, Oral; Adrenal Cortex Hormones; Adult; Aging; Body Mass Index; Cystic Fibrosis; Extre | 2003 |
Intravenous immunoglobulin for cystic fibrosis lung disease: a case series of 16 children.
Topics: Adolescent; Adrenal Cortex Hormones; Child; Child, Preschool; Cystic Fibrosis; Female; Forced Expira | 2004 |
Pulmonary sarcoidosis in a child with cystic fibrosis.
Topics: Adolescent; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Cystic Fibrosis; Female; Follow- | 2005 |
Bioavailability of prednisolone in patients with intestinal malabsorption: the importance of measuring serum protein-binding.
Topics: Administration, Oral; Adult; Aged; Biological Availability; Blood Proteins; Celiac Disease; Crohn Di | 1983 |
A case of chronic gastrointestinal blood loss in cystic fibrosis.
Topics: Adult; Anti-Inflammatory Agents; Chronic Disease; Cystic Fibrosis; Gastrointestinal Hemorrhage; Huma | 1995 |
Rise in total IgE as an indicator of allergic bronchopulmonary aspergillosis in cystic fibrosis.
Topics: Adolescent; Aspergillosis, Allergic Bronchopulmonary; Biomarkers; Child; Child, Preschool; Cystic Fi | 1994 |
[Allergic bronchopulmonary aspergillosis and cystic fibrosis. 2 case reports in adults].
Topics: Acute Disease; Adult; Anti-Bacterial Agents; Aspergillosis, Allergic Bronchopulmonary; Chronic Disea | 1993 |
[Allergic bronchopulmonary aspergillosis (ABPA) in patients with cystic fibrosis (CF): clinical significance, diagnosis and therapy].
Topics: Adolescent; Adult; Aspergillosis, Allergic Bronchopulmonary; Aspergillus fumigatus; Child; Child, Pr | 1996 |
Oral corticosteroids and bone pain after pamidronate in adults with cystic fibrosis.
Topics: Adult; Anti-Infective Agents; Bone Diseases; Cystic Fibrosis; Diphosphonates; Glucocorticoids; Human | 1999 |
Bronchiolitis obliterans organizing pneumonia: a distinct pulmonary complication in cystic fibrosis.
Topics: Adult; Biopsy, Needle; Cryptogenic Organizing Pneumonia; Cystic Fibrosis; Dose-Response Relationship | 2000 |
Cell-mediated immunity in patients with cystic fibrosis.
Topics: Adolescent; Adult; Animals; Antigens; Antigens, Fungal; Aspergillus fumigatus; Cell Migration Inhibi | 1976 |
Letter: Cell-mediated immunity in patients with cystic fibrosis.
Topics: Cystic Fibrosis; Humans; Immunity, Cellular; Prednisolone | 1976 |
Aspergillosis.
Topics: Antifungal Agents; Aspergillosis, Allergic Bronchopulmonary; Child; Cystic Fibrosis; Humans; Itracon | 1992 |
Altered prednisolone pharmacokinetics in patients with cystic fibrosis.
Topics: Administration, Oral; Asthma; Biological Availability; Child; Cystic Fibrosis; Humans; Infusions, In | 1992 |
Cystic fibrosis and allergic bronchopulmonary aspergillosis.
Topics: Aspergillosis, Allergic Bronchopulmonary; Child; Cystic Fibrosis; Female; Humans; Incidence; Lung; P | 1990 |
Enteric-coated prednisolone in cystic fibrosis.
Topics: Aspergillosis, Allergic Bronchopulmonary; Child; Cystic Fibrosis; Humans; Intestinal Absorption; Mal | 1986 |
Cystic fibrosis and coeliac disease: coexistence in two children.
Topics: Biopsy; Body Height; Body Weight; Celiac Disease; Child; Child, Preschool; Chlorides; Cystic Fibrosi | 1973 |
Mucoid enteritis of rabbits. Comparison to cholera and cystic fibrosis.
Topics: Animals; Blood Glucose; Blood Proteins; Cecum; Cholera; Colon; Cystic Fibrosis; Enteritis; Female; H | 1972 |