prednisolone has been researched along with Corneal Ulcer in 71 studies
Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.
Corneal Ulcer: Loss of epithelial tissue from the surface of the cornea due to progressive erosion and necrosis of the tissue; usually caused by bacterial, fungal, or viral infection.
Excerpt | Relevance | Reference |
---|---|---|
"The Steroids for Corneal Ulcers Trial (SCUT) was a randomized, double-masked, placebo-controlled trial assessing outcomes in patients with culture positive bacterial corneal ulcers randomized to receive prednisolone phosphate or placebo." | 5.17 | Emerging moxifloxacin resistance in Pseudomonas aeruginosa keratitis isolates in South India. ( Acharya, NR; Borkar, DS; Lalitha, P; Lietman, TM; Mascarenhas, J; McLeod, SD; Oldenburg, CE; Porco, TC; Rajaraman, R; Ravindran, M; Ray, KJ; Srinivasan, M; Zegans, ME, 2013) |
"In the Steroids for Corneal Ulcers Trial (SCUT), 500 corneal infections were treated with topical moxifloxacin." | 5.17 | Moxifloxacin susceptibility mediates the relationship between causative organism and clinical outcome in bacterial keratitis. ( Acharya, NR; Bharathi, MJ; Glidden, DV; Lalitha, P; Lietman, TM; Manikandan, P; Mascarenhas, J; Nardone, N; Oldenburg, CE; Rajaraman, R; Ravindran, M; Ray, KJ; Srinivasan, M, 2013) |
"Baseline data from a 1:1 randomized, placebo-controlled, double-masked clinical trial comparing prednisolone phosphate, 1%, with placebo as adjunctive therapy for the treatment of bacterial corneal ulcers." | 5.16 | The steroids for corneal ulcers trial: study design and baseline characteristics. ( Acharya, NR; Glidden, DV; Hong, KC; Lalitha, P; Lee, SM; Lietman, TM; Mascarenhas, J; McLeod, SD; Oldenburg, CE; Rajaraman, R; Ravindran, M; Ray, KJ; Srinivasan, M; Zegans, ME, 2012) |
"Subanalyses were performed on data collected in the Steroids for Corneal Ulcers Trial (SCUT), a large randomized controlled trial in which patients were treated with moxifloxacin and were randomly assigned to 1 of 2 adjunctive treatment arms: corticosteroid or placebo (4 times a day with subsequent reduction)." | 5.16 | Pseudomonas aeruginosa keratitis: outcomes and response to corticosteroid treatment. ( Acharya, NR; Glidden, D; Lalitha, P; Lietman, TM; Mascarenhas, J; McLeod, SD; Oldenburg, CE; Rajaraman, R; Ravindran, M; Ray, KJ; Srinivasan, M; Sy, A; Zegans, ME, 2012) |
"A 60-year-old female with a 39°C fever and bilateral parotid swelling diagnosed with mumps and treated for photophobia, pain, redness, and decreased vision in 1 eye, was referred to our hospital when her condition deteriorated despite receiving betamethasone phosphate instillation and antiglaucoma agents for elevated intraocular pressure (52 mm Hg) and iritis." | 3.83 | An Adult Case of Fulminant Mumps Keratitis With Positive Viral RNA in Aqueous Humor Detected by RT-PCR. ( Kitagawa, K; Okamoto, A; Sasaki, H; Shibata, T; Takahashi, Y, 2016) |
" Postoperative uveitis was controlled with oral prednisolone." | 3.72 | Bilateral phacofragmentation in a New Zealand fur seal (Arctocephalus forsteri). ( Barnes, JA; Smith, JS, 2004) |
"To assess the effect of intensive topical and intravenous antibiotics plus oral prednisolone and surgical debridement in Pseudomonas keratoscleritis after pterygium excision." | 3.70 | The treatment of Pseudomonas keratoscleritis after pterygium excision. ( Huang, SC; Lai, HC; Lai, IC, 1999) |
"Perifosine is a novel alkylphospholipid with antiproliferative properties attributed to protein kinase B inhibition." | 2.73 | Ulcerative keratitis in gastrointestinal stromal tumor patients treated with perifosine. ( Araujo, DM; Esmaeli, B; Espandar, L; Hatef, E; Kim, SK; Shome, D; Song, CD; Trent, J, 2008) |
"Reactive arthritis is occasionally associated with conjunctivitis and uveitis, but rarely keratitis." | 1.43 | Painful Acute Corneal Ulceration and Anterior Stromal Keratitis in an Adolescent With Reactive Arthritis. ( AlQahtani, E; Gardiner, J; Lyons, CJ; Moloney, GT; Tsang, H, 2016) |
"Sodium hypochlorite is an effective antibacterial irrigant indicated for the treatment of root canal infections." | 1.40 | Sodium hypochlorite chemical burn in an endodontist's eye during canal treatment using operating microscope. ( Estrela, C; Puente, CG; Regalado Farreras, DC, 2014) |
"Bacterial keratitis results in corneal scarring and subsequent visual impairment." | 1.39 | Improvement in corneal scarring following bacterial keratitis. ( Acharya, NR; Greninger, DA; Keenan, JD; Lietman, TM; Mascarenhas, J; McClintic, SM; Srinivasan, M, 2013) |
"An elderly white woman with stable ocular cicatricial pemphigoid underwent an uncomplicated clear corneal phacoemulsification procedure in the left eye." | 1.37 | Peripheral ulcerative keratitis after cataract surgery in a patient with ocular cicatricial pemphigoid. ( Inglis, A; Kiire, CA; Srinivasan, S, 2011) |
"Peripheral ulcerative keratitis is a destructive process involving perilimbal corneal inflammation and an overlying epithelial defect." | 1.37 | Peripheral ulcerative keratitis in a child. ( Ali, A; Leung, AK; Mireskandari, K, 2011) |
"One month later, a recurrence of PUK on the donor button was noted." | 1.35 | Recurrence of peripheral ulcerative keratitis on the corneoscleral button in a young man treated successfully with oral corticosteroids. ( Bakiah, S; Ibrahim, M; Selvaraja, V; Wahid, WA, 2008) |
"The diagnosis was bilateral vernal keratoconjunctivitis with shield ulcer in the right eye." | 1.35 | Combined therapy for vernal shield ulcer. ( Kumar, S, 2008) |
"Wegener's granulomatosis is a rare necrotising vasculitis not easily diagnosed due to the obscurity of its diverse clinical features." | 1.34 | Unusual eye signs in Wegener's granulomatosis. ( Chan, AY; Choi, PC; Lam, DS; Lam, PT; Li, EK; Liu, DT, 2007) |
"To report a patient with vernal keratoconjunctivitis-induced shield ulcer superinfected with Staphylococcus aureus." | 1.33 | Secondary bacterial keratitis associated with shield ulcer caused by vernal conjunctivitis. ( Akova, YA; Gedik, S; Gür, S, 2006) |
" These results suggest that either salt of prednisolone, when combined with ciprofloxacin, reduces ocular inflammation without affecting the antimicrobial efficacy of the antibiotic." | 1.29 | Prednisolone acetate or prednisolone phosphate concurrently administered with ciprofloxacin for the therapy of experimental Pseudomonas aeruginosa keratitis. ( Callegan, MC; Engel, LS; Hill, JM; Hobden, JA; O'Callaghan, RJ, 1993) |
"Three AIDS patients with ocular herpes zoster infection (mean age at onset, 33." | 1.29 | Herpes zoster peripheral ulcerative keratitis in patients with the acquired immunodeficiency syndrome. ( Belfort, R; Foster, CS; Lane, L; Muccioli, C; Neves, RA; Power, WJ; Rodriguez, A, 1996) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 21 (29.58) | 18.7374 |
1990's | 8 (11.27) | 18.2507 |
2000's | 13 (18.31) | 29.6817 |
2010's | 29 (40.85) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Urkude, J | 1 |
Singh, R | 1 |
Chaniyara, M | 1 |
Pujari, A | 1 |
Wu, YT | 1 |
Truong, TN | 2 |
Tam, C | 1 |
Mendoza, MN | 2 |
Zhu, L | 1 |
Evans, DJ | 1 |
Fleiszig, SMJ | 1 |
Ashar, JN | 1 |
Mathur, A | 1 |
Sangwan, VS | 1 |
Oldenburg, CE | 10 |
Lalitha, P | 10 |
Srinivasan, M | 14 |
Rajaraman, R | 9 |
Ravindran, M | 8 |
Mascarenhas, J | 11 |
Borkar, DS | 1 |
Ray, KJ | 11 |
Zegans, ME | 8 |
McLeod, SD | 8 |
Porco, TC | 2 |
Lietman, TM | 14 |
Acharya, NR | 14 |
Papakostas, TD | 1 |
Kohanim, S | 1 |
Skondra, D | 1 |
Lo, K | 1 |
Chodosh, J | 1 |
O'Brien, KS | 2 |
Glidden, DV | 5 |
Whitcher, JP | 4 |
Keenan, JD | 3 |
McClintic, SM | 2 |
Prajna, NV | 2 |
Schneider, LR | 1 |
Shorter, E | 1 |
Cortina, MS | 1 |
Krall, P | 1 |
Kubal, A | 1 |
Regalado Farreras, DC | 1 |
Puente, CG | 1 |
Estrela, C | 1 |
Shibata, T | 1 |
Takahashi, Y | 1 |
Okamoto, A | 1 |
Sasaki, H | 1 |
Kitagawa, K | 1 |
Höllhumer, R | 1 |
Zairani Mz, A | 1 |
Watson, S | 1 |
Lyons, CJ | 1 |
AlQahtani, E | 1 |
Tsang, H | 1 |
Moloney, GT | 1 |
Gardiner, J | 1 |
Wahid, WA | 1 |
Selvaraja, V | 1 |
Bakiah, S | 1 |
Ibrahim, M | 1 |
Mahalakshmi, R | 2 |
Chidambaram, JD | 1 |
Lee, S | 1 |
Hong, KC | 3 |
Zegans, M | 1 |
McLeod, S | 2 |
Berger, EA | 1 |
McClellan, SA | 1 |
Barrett, RP | 1 |
Hazlett, LD | 1 |
Das, S | 1 |
Sharma, S | 1 |
Sahu, SK | 1 |
Vemuganti, GK | 1 |
Kiire, CA | 1 |
Srinivasan, S | 1 |
Inglis, A | 1 |
Meskin, SW | 1 |
Carlson, EM | 1 |
Lee, SM | 2 |
Leung, AK | 1 |
Mireskandari, K | 1 |
Ali, A | 1 |
Sy, A | 2 |
Glidden, D | 2 |
Praidou, A | 1 |
Androudi, S | 1 |
Kanonidou, E | 1 |
Konidaris, V | 1 |
Alexandridis, A | 1 |
Brazitikos, P | 1 |
Priya, JL | 1 |
Labiris, G | 1 |
Troeber, L | 1 |
Gatzioufas, Z | 1 |
Stavridis, E | 1 |
Seitz, B | 1 |
See, CW | 1 |
Saravanan, S | 1 |
Esterberg, EJ | 1 |
Glaser, TS | 1 |
Tu, EY | 1 |
Greninger, DA | 1 |
Prajna, L | 2 |
Geetha, M | 1 |
Karpagam, R | 1 |
Sun, CQ | 1 |
Manikandan, P | 1 |
Bharathi, MJ | 1 |
Nardone, N | 1 |
CROMPTON, DO | 1 |
ARNOTT, EJ | 1 |
GREAVES, DP | 1 |
Lee, EJ | 1 |
Fleiszig, SM | 1 |
Barnes, JA | 1 |
Smith, JS | 1 |
Jin, GJ | 1 |
Lyle, WA | 1 |
Merkley, KH | 1 |
Lanier, JD | 1 |
Dawson, CR | 1 |
Oh, JO | 1 |
Tan, MH | 1 |
Chen, SD | 1 |
Rubinstein, A | 1 |
Bron, AJ | 1 |
Gedik, S | 1 |
Akova, YA | 1 |
Gür, S | 1 |
Chan, AY | 1 |
Li, EK | 1 |
Choi, PC | 1 |
Liu, DT | 1 |
Lam, PT | 1 |
Lam, DS | 1 |
Chawla, B | 1 |
Agarwal, P | 1 |
Tandon, R | 1 |
Titiyal, JS | 1 |
Kumar, S | 1 |
Shome, D | 1 |
Trent, J | 1 |
Espandar, L | 1 |
Hatef, E | 1 |
Araujo, DM | 1 |
Song, CD | 1 |
Kim, SK | 1 |
Esmaeli, B | 1 |
Chen, A | 1 |
Knecht, CD | 1 |
Schiller, AG | 1 |
Small, E | 1 |
Phillips, K | 1 |
Arffa, R | 1 |
Cintron, C | 1 |
Rose, J | 1 |
Miller, D | 2 |
Kublin, CL | 1 |
Kenyon, KR | 2 |
Petroutsos, G | 1 |
Guimaraes, R | 1 |
Giraud, JP | 1 |
Pouliquen, Y | 1 |
Poirier, RH | 1 |
Hobden, JA | 1 |
Engel, LS | 1 |
Hill, JM | 1 |
Callegan, MC | 1 |
O'Callaghan, RJ | 1 |
Neves, RA | 1 |
Rodriguez, A | 1 |
Power, WJ | 1 |
Muccioli, C | 1 |
Lane, L | 1 |
Belfort, R | 1 |
Foster, CS | 2 |
Scott, IU | 1 |
Flynn, HW | 1 |
Feuer, W | 1 |
Pflugfelder, SC | 1 |
Alfonso, EC | 1 |
Forster, RK | 2 |
Dada, T | 1 |
Kumar, A | 1 |
Sharma, N | 1 |
Yang, J | 1 |
Baltatzis, S | 1 |
Huang, SC | 1 |
Lai, HC | 1 |
Lai, IC | 1 |
Smith, VA | 1 |
Hoh, HB | 1 |
Easty, DL | 3 |
Sirois, D | 1 |
Leigh, JE | 1 |
Sollecito, TP | 1 |
el-Gammal, MY | 1 |
el-Din Mostafa, MS | 1 |
Rebell, G | 1 |
Stiles, W | 1 |
Smolin, G | 1 |
Okumoto, M | 1 |
Jones, BR | 1 |
McGill, JI | 2 |
Steele, AD | 1 |
Lesher, MP | 1 |
Lohman, LE | 1 |
Yeakley, W | 1 |
Lass, J | 1 |
Aonuma, Y | 1 |
Itoh, M | 1 |
Hakamata, M | 1 |
Endo, S | 1 |
Ohashi, H | 1 |
Okugawa, T | 1 |
Yamazaki, N | 1 |
Climenhaga, DB | 1 |
Jackson, WB | 1 |
Delcarpio, J | 1 |
Struck, HG | 1 |
Franke, C | 1 |
Tost, M | 1 |
Taube, C | 1 |
Schein, OD | 1 |
Wasson, PJ | 1 |
Boruchoff, SA | 1 |
Aronson, SB | 1 |
Moore, TE | 1 |
Macdonald, A | 1 |
Levy, I | 1 |
Holt-Wilson, AD | 1 |
Shilling, J | 1 |
Gornig, H | 1 |
Chignell, AH | 1 |
Chesterton, JR | 1 |
Thomsitt, J | 1 |
Willis, WE | 1 |
Laibson, PR | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Steroids for Corneal Ulcers Trial[NCT00324168] | Phase 4 | 500 participants (Actual) | Interventional | 2006-09-30 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
LogMAR (logarithm of the Minimum Angle of Resolution) is a measure of visual acuity in which the smaller values indicate better visual acuity. (NCT00324168)
Timeframe: 3 months from enrollment
Intervention | logMAR (Mean) |
---|---|
Steroid | 0.42 |
Placebo | 0.41 |
LogMAR (logarithm of the Minimum Angle of Resolution) is a measure of visual acuity in which the smaller values indicate better visual acuity. (NCT00324168)
Timeframe: 12 months from enrollment
Intervention | logMAR (Mean) |
---|---|
Steroid | 2.90 |
Placebo | 2.87 |
LogMAR (logarithm of the Minimum Angle of Resolution) is a measure of visual acuity in which the smaller values indicate better visual acuity. (NCT00324168)
Timeframe: 3 months from enrollment
Intervention | logMAR (Mean) |
---|---|
Steroid | 0.48 |
Placebo | 0.49 |
Best spectacle-corrected visual acuity (BSCVA) for this outcome is measured in logMAR (logarithm of the Minimum Angle of Resolution) in which smaller values indicate better visual acuity. Minimum inhibitory concentration (MIC) to moxifloxacin was measured by E test and a log2-transformation of MIC was used in all analyses. In this analysis we add MIC to the model examining BSCVA at 3 months. (NCT00324168)
Timeframe: 3 months after enrollment
Intervention | logMAR (Mean) |
---|---|
Steroid | 0.50 |
Placebo | 0.46 |
(NCT00324168)
Timeframe: 3 months from enrollment
Intervention | mm (Mean) |
---|---|
Steroid | 3.07 |
Placebo | 3.02 |
(NCT00324168)
Timeframe: At the time of perforation
Intervention | participants (Number) |
---|---|
Steroid | 7 |
Placebo | 8 |
This outcome measured time from enrollment to resolution of the epithelial defect in days for up to 21 days. For three weeks patients were examined every 3 days for size of epithelial defect until the defect was gone. (NCT00324168)
Timeframe: From enrollment up to 21 days
Intervention | days (Mean) |
---|---|
Steroid | 9.77 |
Placebo | 9.43 |
BSCVA measured in logMAR will be examined by categories infiltrate depth (categorized by depth percentage) by mean and standard deviation as well as in a regression model. (NCT00324168)
Timeframe: 3 months from enrollment
Intervention | logMAR (Mean) | ||
---|---|---|---|
>0-33% | >33%-67% | >67%-100% | |
Placebo | 0.26 | 0.47 | 0.86 |
Steroid | 0.35 | 0.52 | 0.80 |
BSCVA measured in logMAR will be estimated by causative organism (either Nocardia spp, Streptococcus pneumoniae, Moraxella spp, or Pseudomonas aeruginosa). BSCVA will be examined for each causative organism by mean and standard deviation as well as in a regression model. (NCT00324168)
Timeframe: 3 months after enrollment
Intervention | logMAR (Mean) | |||
---|---|---|---|---|
Nocardia spp | Streptococcus pneumoniae | Moraxella spp | Pseudomonas aeruginosa | |
Placebo | 0.36 | 0.52 | 0.26 | 0.45 |
Steroid | 0.54 | 0.49 | 0.46 | 0.53 |
Best spectacle-corrected visual acuity (BSCVA) for this subgroup analysis was measured in logMAR and then categorized by equivalent Snellen fractions (NCT00324168)
Timeframe: 3 months from enrollment
Intervention | logMAR (Mean) | ||
---|---|---|---|
<20/40 | 20/40 to 20/800 | Counting fingers (CF) or worse | |
Placebo | -0.02 | 0.38 | 1.15 |
Steroid | 0.06 | 0.36 | 1.00 |
Best-spectacle visual acuity (BSCVA) at 3 months from enrollment is stratified by categories of infiltrate/scar size and examined by treatment arm (NCT00324168)
Timeframe: 3 months from enrollment
Intervention | logMAR (Mean) | |||
---|---|---|---|---|
0-1.90 mm | 1.91-2.70 mm | 2.71-4.06 mm | 4.07-8.90 mm | |
Placebo | 0.19 | 0.29 | 0.53 | 0.96 |
Steroid | 0.18 | 0.39 | 0.53 | 0.85 |
2 reviews available for prednisolone and Corneal Ulcer
Article | Year |
---|---|
Mooren's-type ulceration associated with severe hidradenitis suppurativa: a case report and literature review.
Topics: Amnion; Antibodies, Monoclonal; Aza Compounds; Conjunctiva; Corneal Perforation; Corneal Ulcer; Derm | 2011 |
Staphylococcal blepharitis.
Topics: Anti-Bacterial Agents; Blepharitis; Chronic Disease; Conjunctivitis; Corneal Diseases; Corneal Ulcer | 1977 |
16 trials available for prednisolone and Corneal Ulcer
Article | Year |
---|---|
Emerging moxifloxacin resistance in Pseudomonas aeruginosa keratitis isolates in South India.
Topics: Anti-Bacterial Agents; Aza Compounds; Communicable Diseases, Emerging; Cornea; Corneal Ulcer; Double | 2013 |
The steroids for corneal ulcers trial (SCUT): secondary 12-month clinical outcomes of a randomized controlled trial.
Topics: Administration, Topical; Adult; Anti-Bacterial Agents; Aza Compounds; Bacteria; Corneal Ulcer; Doubl | 2014 |
Visual recovery in treated bacterial keratitis.
Topics: Adult; Aged; Anti-Bacterial Agents; Aza Compounds; Corneal Ulcer; Eye Infections, Bacterial; Female; | 2014 |
Visual outcomes in treated bacterial keratitis: four years of prospective follow-up.
Topics: Adult; Aged; Anti-Bacterial Agents; Aza Compounds; Corneal Ulcer; Double-Blind Method; Eye Infection | 2014 |
Corticosteroids for bacterial corneal ulcers.
Topics: Adult; Aged; Corneal Ulcer; Double-Blind Method; Epithelium, Corneal; Eye Infections, Bacterial; Fea | 2009 |
The steroids for corneal ulcers trial: study design and baseline characteristics.
Topics: Administration, Topical; Adult; Anti-Infective Agents; Aza Compounds; Bacteria; Cornea; Corneal Ulce | 2012 |
Corticosteroids for bacterial keratitis: the Steroids for Corneal Ulcers Trial (SCUT).
Topics: Administration, Topical; Adult; Anti-Infective Agents; Aza Compounds; Bacteria; Cornea; Corneal Ulce | 2012 |
Pseudomonas aeruginosa keratitis: outcomes and response to corticosteroid treatment.
Topics: Adult; Anti-Infective Agents; Aza Compounds; Corneal Ulcer; Double-Blind Method; Eye Infections, Bac | 2012 |
Nocardia keratitis: clinical course and effect of corticosteroids.
Topics: Administration, Topical; Adult; Anti-Infective Agents; Aza Compounds; Corneal Ulcer; Double-Blind Me | 2012 |
Prior elicitation and Bayesian analysis of the Steroids for Corneal Ulcers Trial.
Topics: Administration, Topical; Anti-Infective Agents; Aza Compounds; Bayes Theorem; Corneal Ulcer; Double- | 2012 |
Fluoroquinolone treatment and susceptibility of isolates from bacterial keratitis.
Topics: Adult; Anti-Bacterial Agents; Aza Compounds; Bacteria; Corneal Ulcer; Double-Blind Method; Drug Resi | 2013 |
Moxifloxacin susceptibility mediates the relationship between causative organism and clinical outcome in bacterial keratitis.
Topics: Administration, Topical; Anti-Infective Agents; Aza Compounds; Bacteria; Corneal Ulcer; Disease Susc | 2013 |
Ulcerative keratitis in gastrointestinal stromal tumor patients treated with perifosine.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Corne | 2008 |
Does in vitro susceptibility predict clinical outcome in bacterial keratitis?
Topics: Anti-Infective Agents; Aza Compounds; Bacteria; Corneal Ulcer; Disease Susceptibility; Eye Infection | 2008 |
[Animal experiment and clinical studies of the use of anti-inflammatory agents in chemical burns of the eye].
Topics: Animals; Burns, Chemical; Corneal Ulcer; Dexamethasone; Eye Burns; Female; Humans; Indomethacin; Mal | 1988 |
The aetiology and treatment of marginal corneal ulcers.
Topics: Chromones; Corneal Ulcer; Cromolyn Sodium; Humans; Ointments; Ophthalmic Solutions; Oxyphenbutazone; | 1971 |
53 other studies available for prednisolone and Corneal Ulcer
Article | Year |
---|---|
Customised crescentic corneal transplant with conjunctival resection in an atypical case of malignant Mooren's ulcer.
Topics: Corneal Transplantation; Corneal Ulcer; Humans; Male; Prednisolone; Slit Lamp Microscopy; Treatment | 2017 |
Impact of topical corticosteroid pretreatment on susceptibility of the injured murine cornea to Pseudomonas aeruginosa colonization and infection.
Topics: Administration, Ophthalmic; Animals; Cornea; Corneal Injuries; Corneal Ulcer; Disease Models, Animal | 2019 |
Immunosuppression for Mooren's ulcer: evaluation of the stepladder approach--topical, oral and intravenous immunosuppressive agents.
Topics: Administration, Oral; Administration, Topical; Anti-Inflammatory Agents; Corneal Ulcer; Dose-Respons | 2013 |
Medical management of Alternaria keratitis with endophthalmitis in a patient with a corneal graft.
Topics: Administration, Oral; Administration, Topical; Adult; Alternaria; Alternariosis; Antifungal Agents; | 2014 |
Man with blurry vision.
Topics: Anterior Chamber; Combined Modality Therapy; Contact Lenses; Corneal Ulcer; Diabetes Complications; | 2014 |
Herpes zoster stromal keratitis after varicella vaccine booster in a pediatric patient.
Topics: Administration, Topical; Chickenpox Vaccine; Child; Corneal Stroma; Corneal Ulcer; Female; Glucocort | 2014 |
Sodium hypochlorite chemical burn in an endodontist's eye during canal treatment using operating microscope.
Topics: Accidents, Occupational; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Anti-Inflammatory Agents; | 2014 |
An Adult Case of Fulminant Mumps Keratitis With Positive Viral RNA in Aqueous Humor Detected by RT-PCR.
Topics: Administration, Oral; Administration, Topical; Aqueous Humor; Betamethasone; Corneal Ulcer; Eye Infe | 2016 |
Hemorrhagic Descemet Membrane Detachment Following Syphilitic Interstitial Keratitis.
Topics: Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents; Chloramphenicol; Combined Modality Therapy; C | 2016 |
Painful Acute Corneal Ulceration and Anterior Stromal Keratitis in an Adolescent With Reactive Arthritis.
Topics: Adolescent; Arthritis, Reactive; Corneal Stroma; Corneal Ulcer; Diagnosis, Differential; Eye Pain; G | 2016 |
Recurrence of peripheral ulcerative keratitis on the corneoscleral button in a young man treated successfully with oral corticosteroids.
Topics: Administration, Oral; Adult; Amnion; Anti-Infective Agents; Ciprofloxacin; Corneal Transplantation; | 2008 |
VIP promotes resistance in the Pseudomonas aeruginosa-infected cornea by modulating adhesion molecule expression.
Topics: Animals; Cell Adhesion Molecules; Cell Movement; Corneal Ulcer; Disease Models, Animal; Enzyme-Linke | 2010 |
Intraocular invasion by microsporidial spores in a case of stromal keratitis.
Topics: Acyclovir; Adult; Biguanides; Corneal Stroma; Corneal Ulcer; Drug Therapy, Combination; Endothelium, | 2011 |
Peripheral ulcerative keratitis after cataract surgery in a patient with ocular cicatricial pemphigoid.
Topics: Aged, 80 and over; Cataract; Combined Modality Therapy; Corneal Ulcer; Female; Glucocorticoids; Huma | 2011 |
Peripheral ulcerative keratitis in a child.
Topics: Child; Corneal Ulcer; Eye Pain; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Methotrex | 2011 |
Bilateral herpes simplex keratitis presenting as peripheral ulcerative keratitis.
Topics: Acyclovir; Antigens, Viral; Antiviral Agents; Corneal Ulcer; Diagnosis, Differential; Drug Therapy, | 2012 |
Bilateral Fusarium oxysporum keratitis after laser in situ keratomileusis.
Topics: Anti-Bacterial Agents; Anti-Infective Agents, Local; Corneal Ulcer; DNA, Fungal; Drug Therapy, Combi | 2012 |
Improvement in corneal scarring following bacterial keratitis.
Topics: Adult; Aged; Aza Compounds; Cicatrix; Corneal Ulcer; Eye Infections, Bacterial; Female; Fluoroquinol | 2013 |
CORTICOSTEROIDS EXACERBATE OCULAR HERPES SIMPLEX.
Topics: Administration, Topical; Adolescent; Adrenal Cortex Hormones; Betamethasone; Corneal Ulcer; Drug The | 1964 |
ORBITAL INVOLVEMENT IN RIEDEL'S THYROIDITIS.
Topics: Corneal Ulcer; Drug Therapy; Eye Manifestations; Humans; Orbit; Pathology; Prednisolone; Thyroiditis | 1965 |
A comparison of invasive and cytotoxic Pseudomonas aeruginosa strain-induced corneal disease responses to therapeutics.
Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Cornea; Corneal Ulcer; Disease Models, Anim | 2003 |
Bilateral phacofragmentation in a New Zealand fur seal (Arctocephalus forsteri).
Topics: Animals; Atropine; Cataract Extraction; Corneal Edema; Corneal Ulcer; Fur Seals; Male; Mydriatics; P | 2004 |
Late-onset idiopathic diffuse lamellar keratitis after laser in situ keratomileusis.
Topics: Administration, Topical; Astigmatism; Corneal Ulcer; Female; Glucocorticoids; Humans; Keratomileusis | 2005 |
Proflavine and light in the treatment of experimental herpetic ocular infections.
Topics: Animals; Corneal Ulcer; Drug Therapy, Combination; Idoxuridine; Keratitis, Herpetic; Male; Photochem | 1974 |
Corneal perforation due to severe peripheral ulcerative keratitis in Crohn disease.
Topics: Aged; Combined Modality Therapy; Conjunctiva; Corneal Ulcer; Crohn Disease; Glucocorticoids; Humans; | 2006 |
Secondary bacterial keratitis associated with shield ulcer caused by vernal conjunctivitis.
Topics: Anti-Bacterial Agents; Cefazolin; Child; Conjunctivitis, Allergic; Corneal Ulcer; Cyclopentolate; Dr | 2006 |
Unusual eye signs in Wegener's granulomatosis.
Topics: Anti-Inflammatory Agents; Corneal Ulcer; Cyclophosphamide; Female; Granulomatosis with Polyangiitis; | 2007 |
Peripheral ulcerative keratitis with bilateral optic nerve involvement as an initial presentation of acute lymphocytic leukemia in an adult.
Topics: Adult; Corneal Ulcer; Drug Therapy, Combination; Female; Fluoroquinolones; Gatifloxacin; Humans; Int | 2009 |
Combined therapy for vernal shield ulcer.
Topics: Adult; Conjunctivitis, Allergic; Corneal Ulcer; Cyclosporine; Drug Therapy, Combination; Follow-Up S | 2008 |
Focal degeneration of the cornea with sequestration in a cat.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Atropine; Cat Diseases; Cats; Chloramphe | 1966 |
Effects of prednisolone and medroxyprogesterone on corneal wound healing, ulceration, and neovascularization.
Topics: Animals; Collagen; Cornea; Corneal Injuries; Corneal Ulcer; Medroxyprogesterone; Medroxyprogesterone | 1983 |
Corticosteroids and corneal epithelial wound healing.
Topics: Animals; Cornea; Corneal Ulcer; Dexamethasone; Epithelium; Female; Glucocorticoids; Male; Prednisolo | 1982 |
Herpetic ocular infections of childhood.
Topics: Adolescent; Atropine; Child; Child, Preschool; Corneal Ulcer; Drug Resistance, Microbial; Female; Fo | 1980 |
Prednisolone acetate or prednisolone phosphate concurrently administered with ciprofloxacin for the therapy of experimental Pseudomonas aeruginosa keratitis.
Topics: Animals; Aqueous Humor; Ciprofloxacin; Corneal Ulcer; Disease Models, Animal; Drug Therapy, Combinat | 1993 |
Herpes zoster peripheral ulcerative keratitis in patients with the acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Administration, Oral; Adult; Anti-Inflammatory Agents | 1996 |
Endophthalmitis associated with microbial keratitis.
Topics: Anti-Inflammatory Agents; Bacteria; Corneal Ulcer; Endophthalmitis; Eye Infections, Bacterial; Eye I | 1996 |
Sympathetic ophthalmia associated with antecedent adherent leucoma--a rare association.
Topics: Administration, Oral; Adult; Corneal Opacity; Corneal Ulcer; Dexamethasone; Glucocorticoids; Humans; | 1998 |
Peripheral ulcerative keratitis after Salmonella gastroenteritis.
Topics: Aged; Cornea; Corneal Neovascularization; Corneal Ulcer; Cyclopentolate; Drug Therapy, Combination; | 1998 |
The treatment of Pseudomonas keratoscleritis after pterygium excision.
Topics: Administration, Oral; Aged; Anti-Bacterial Agents; Corneal Ulcer; Debridement; Drug Therapy, Combina | 1999 |
Role of ocular matrix metalloproteinases in peripheral ulcerative keratitis.
Topics: Copper; Cornea; Corneal Ulcer; Culture Techniques; Electrophoresis, Polyacrylamide Gel; Eye; Gelatin | 1999 |
Oral pemphigus vulgaris preceding cutaneous lesions: recognition and diagnosis.
Topics: Adult; Aged; Anti-Inflammatory Agents; Autoantibodies; Azathioprine; Corneal Ulcer; Cyclophosphamide | 2000 |
The effect of local and systemic steroids on healing of corneal wounds.
Topics: Administration, Topical; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Animals; Anti-Inflamm | 1976 |
Recurrent keratitis due to Acremonium potronii.
Topics: Adolescent; Atropine; Bacitracin; Corneal Injuries; Corneal Ulcer; Cyanoacrylates; Eye Injuries; Gen | 1975 |
Recurrent suppurative kerato-uveitis with loss of eye due to infection by Acanthamoeba castellani.
Topics: Amebiasis; Anti-Bacterial Agents; Corneal Transplantation; Corneal Ulcer; Doxycycline; Eukaryota; Hu | 1975 |
Recurrence of herpetic stromal keratitis after a conjunctival flap surgical procedure.
Topics: Aged; Cataract Extraction; Conjunctiva; Corneal Stroma; Corneal Ulcer; Eye Infections, Viral; Female | 1992 |
[A patient with temporal arteritis presenting corneal ulcer as his first symptom].
Topics: Aged; Corneal Ulcer; Cyclophosphamide; Drug Therapy, Combination; Giant Cell Arteritis; Humans; Male | 1989 |
Peripheral corneal ulcer associated with benign hypergammaglobulinemic purpura.
Topics: Corneal Ulcer; Female; Humans; Hydrocortisone; Keratitis; Middle Aged; Plasmapheresis; Prednisolone; | 1988 |
Microbial keratitis associated with contaminated ocular medications.
Topics: Administration, Topical; Aged; Aged, 80 and over; Corneal Ulcer; Drug Contamination; Female; Humans; | 1988 |
Corticosteroid therapy in central stromal keratitis.
Topics: Adrenal Cortex Hormones; Adult; Aged; Antibody Formation; Antigen-Antibody Reactions; Bacteria; Chil | 1969 |
Erythrodermic psoriasis with corneal ulcers and ophthalmological sequelae.
Topics: Adult; Beds; Corneal Ulcer; Dermatitis, Exfoliative; Female; Humans; Methotrexate; Panophthalmitis; | 1971 |
[Topical prednisolone therapy of corneal ulcers].
Topics: Administration, Topical; Adult; Aged; Anti-Inflammatory Agents; Corneal Ulcer; Female; Follow-Up Stu | 1972 |
Marginal ulceration of the cornea.
Topics: Adolescent; Adult; Aged; Corneal Ulcer; Eye; Eye Foreign Bodies; Female; Humans; Male; Middle Aged; | 1970 |
Intractable Mycobacterium fortuitum corneal ulcer in man.
Topics: Accidents, Occupational; Anti-Bacterial Agents; Antitubercular Agents; Chronic Disease; Corneal Ulce | 1971 |