Page last updated: 2024-11-06

prednisolone and Corneal Edema

prednisolone has been researched along with Corneal Edema in 37 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Corneal Edema: An excessive amount of fluid in the cornea due to damage of the epithelium or endothelium causing decreased visual acuity.

Research Excerpts

ExcerptRelevanceReference
"To report the long-term outcomes of topical ganciclovir (GCV) and corticosteroids as a maintenance therapy for cytomegalovirus (CMV) corneal endotheliitis."7.83Long-Term Topical Ganciclovir and Corticosteroids Preserve Corneal Endothelial Function in Cytomegalovirus Corneal Endotheliitis. ( Chung, YC; Fan, NW; Kuo, YS; Lin, PY; Liu, CJ; Liu, YC, 2016)
" Using a rabbit model, the effects of trifluridine (F3TdR) on corneal edema and stromal disease were examined when combined with each of three immunosuppressive agents."7.68Therapeutic response of herpes simplex virus-induced corneal edema to trifluridine in combination with immunosuppressive agents. ( O'Brien, WJ; Taylor, JL, 1991)
"In this high-dose pulsed-therapy regimen, difluprednate reduced inflammation more effectively than prednisolone acetate, resulting in more rapid return of vision."5.15A multicenter randomized controlled fellow eye trial of pulse-dosed difluprednate 0.05% versus prednisolone acetate 1% in cataract surgery. ( Donnenfeld, ED; Fiore, J; Gobbo, A; Holland, EJ; Perry, HD; Prince, J; Sandoval, HP; Shull, ER; Solomon, KD, 2011)
" A diagnosis of oleander-associated ocular inflammation with secondary corneal edema was made, given the temporal relationship, and treatment was initiated with topical prednisolone and cyclopentolate."4.12Oleander-Associated Keratitis and Uveitis. ( Baratz, KH; Farazdaghi, MK; Patel, SV; Tailor, PD, 2022)
"To report the long-term outcomes of topical ganciclovir (GCV) and corticosteroids as a maintenance therapy for cytomegalovirus (CMV) corneal endotheliitis."3.83Long-Term Topical Ganciclovir and Corticosteroids Preserve Corneal Endothelial Function in Cytomegalovirus Corneal Endotheliitis. ( Chung, YC; Fan, NW; Kuo, YS; Lin, PY; Liu, CJ; Liu, YC, 2016)
"A 64 year-old female with Parkinson disease treated with amantadine for two years who suddenly suffered bilateral corneal oedema."3.78[Corneal toxicity due to amantadine]. ( Avendaño-Cantos, EM; Celis-Sánchez, J; Gálvez-Martínez, J; González Del Valle, F; López-Arroquia, E; Mesa-Varona, D, 2012)
" Postoperative uveitis was controlled with oral prednisolone."3.72Bilateral phacofragmentation in a New Zealand fur seal (Arctocephalus forsteri). ( Barnes, JA; Smith, JS, 2004)
" Using a rabbit model, the effects of trifluridine (F3TdR) on corneal edema and stromal disease were examined when combined with each of three immunosuppressive agents."3.68Therapeutic response of herpes simplex virus-induced corneal edema to trifluridine in combination with immunosuppressive agents. ( O'Brien, WJ; Taylor, JL, 1991)
"Atopic dermatitis is a relatively common hereditary dermatologic condition."2.41Atopic dermatitis: a case report and current clinical review of systemic and ocular manifestations. ( Bachman, JA; Brandonisio, TM; Sears, JM, 2001)
" Breed, age at diagnosis, weight, systemic disease status, eye affected, ophthalmic examination findings, systemic and topical therapy instituted, dosage and duration of therapy, visual outcome and histopathological analyses were recorded in cases meeting the inclusion criteria."1.43An association between systemic cyclosporine administration and development of acute bullous keratopathy in cats. ( Bartoe, JT; Curran, PG; Gemensky-Metzler, AJ; Petersen-Jones, SM; Pierce, KE; Townsend, WM; Wilkie, DA, 2016)
"Common postoperative complications were cataract and graft infiltrate."1.38Long-term outcomes of penetrating keratoplasty for keratoconus with resolved corneal hydrops. ( Basu, S; Reddy, JC; Sangwan, VS; Vaddavalli, PK; Vemuganti, GK, 2012)
" Reduction in the dosage of topical corticosteroid and medical treatment of the raised IOP resulted in resolution of the microcystic edema and interface fluid accumulation."1.31Interface fluid after laser in situ keratomileusis. ( Fogla, R; Padmanabhan, P; Rao, SK, 2001)

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (10.81)18.2507
2000's11 (29.73)29.6817
2010's19 (51.35)24.3611
2020's3 (8.11)2.80

Authors

AuthorsStudies
Tailor, PD1
Farazdaghi, MK1
Patel, SV1
Baratz, KH1
Moshirfar, M2
Payne, C1
Tauber, J1
Kang, JJ1
Mifflin, MD1
Pasricha, N1
Djalilian, A1
Soleimani, M1
Ng, H1
Mathan, J1
Patel, DV1
Hixson, A1
Blanc, S1
Sowka, J1
Kim, SY2
Chung, YK1
Lee, YC1
Porzukowiak, TR1
Ly, K1
Pierce, KE1
Wilkie, DA1
Gemensky-Metzler, AJ1
Curran, PG1
Townsend, WM1
Petersen-Jones, SM1
Bartoe, JT1
Fan, NW1
Chung, YC1
Liu, YC1
Liu, CJ1
Kuo, YS1
Lin, PY1
Ahn, JH1
Kim, DH1
Richards, A1
Hamilton, C1
Seamone, CD1
Darvish, M1
Gupta, RR1
Ranjan, A1
Murthy, SI1
Rathi, VM1
Sangwan, VS2
Bronner, A1
Jun, EJ1
Chung, SK1
Ghaffariyeh, A1
Honarpisheh, N1
Bayar, SA1
Altinors, DD1
Kucukerdonmez, C1
Akova, YA1
Jhanji, V1
Agarwal, T1
Sharma, N1
Vajpayee, RB1
Chiang, CC1
Lin, TH1
Tien, PT1
Tsai, YY1
Donnenfeld, ED1
Holland, EJ1
Solomon, KD1
Fiore, J1
Gobbo, A1
Prince, J1
Sandoval, HP1
Shull, ER1
Perry, HD1
Basu, S1
Reddy, JC1
Vaddavalli, PK1
Vemuganti, GK1
Olson, EA1
Tu, EY1
Basti, S1
Sham, CW1
Levinson, RD1
Avendaño-Cantos, EM1
Celis-Sánchez, J1
Mesa-Varona, D1
Gálvez-Martínez, J1
López-Arroquia, E1
González Del Valle, F1
Dhingra, N1
Watts, MT1
Asano-Kato, N1
Toda, I1
Tsubota, K1
Wallin, TR1
Weikert, MP1
Barnes, JA1
Smith, JS1
Al-Torbak, A1
Malak, M1
Teichmann, KD1
Wagoner, MD1
McLeod, SD1
Mather, R1
Hwang, DG1
Margolis, TP1
Choi, HW1
Moon, SW1
Nam, KH1
Chung, SH1
Burnstein, Y1
Shelton, K1
Higginbotham, EJ1
Brandonisio, TM1
Bachman, JA1
Sears, JM1
Fogla, R1
Rao, SK1
Padmanabhan, P1
Shaikh, NM1
Shaikh, S1
Singh, K1
Manche, E1
Rowson, NJ1
Dart, JK1
Buckley, RJ1
O'Brien, WJ1
Taylor, JL1
Hersh, PS1
Rice, BA1
Baer, JC1
Wells, PA1
Lynch, SE1
McGuigan, LJ1
Foster, CS1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Masked Multi-center Safety & Efficacy Study of the Effects of Preoperative & Postoperative Cataract Surgery Use of Difluprednate Ophthalmic Emulsion, 0.05% Compared to Prednisolone Acetate Ophthalmic Suspension 1% on Visual Acuity & Corneal [NCT01244334]Phase 452 participants (Actual)Interventional2009-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for prednisolone and Corneal Edema

ArticleYear
Multiple parallel-line endotheliitis: case report and literature review of an emerging entity.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2016, Volume: 51, Issue:3

    Topics: Anti-Bacterial Agents; Corneal Edema; Corneal Stroma; Corneal Topography; Drug Therapy, Combination;

2016
Atopic dermatitis: a case report and current clinical review of systemic and ocular manifestations.
    Optometry (St. Louis, Mo.), 2001, Volume: 72, Issue:2

    Topics: Adrenergic beta-Antagonists; Cataract; Conjunctivitis, Allergic; Corneal Edema; Dermatitis, Atopic;

2001

Trials

1 trial available for prednisolone and Corneal Edema

ArticleYear
A multicenter randomized controlled fellow eye trial of pulse-dosed difluprednate 0.05% versus prednisolone acetate 1% in cataract surgery.
    American journal of ophthalmology, 2011, Volume: 152, Issue:4

    Topics: Aged; Aged, 80 and over; Cell Count; Cornea; Corneal Edema; Double-Blind Method; Endothelium, Cornea

2011

Other Studies

34 other studies available for prednisolone and Corneal Edema

ArticleYear
Oleander-Associated Keratitis and Uveitis.
    Cornea, 2022, Oct-01, Volume: 41, Issue:10

    Topics: Corneal Edema; Cyclopentolate; Female; Humans; Inflammation; Keratitis; Middle Aged; Moxifloxacin; N

2022
Unilateral vortex keratopathy of unknown etiology.
    Journal of cataract and refractive surgery, 2022, 10-01, Volume: 48, Issue:10

    Topics: Anti-Bacterial Agents; Contact Lenses, Hydrophilic; Corneal Dystrophies, Hereditary; Corneal Edema;

2022
Acute Corneal Hydrops in a Young Man.
    JAMA ophthalmology, 2020, 04-01, Volume: 138, Issue:4

    Topics: Acute Disease; Anti-Inflammatory Agents; Corneal Edema; Corneal Neovascularization; Descemet Membran

2020
Monitoring keratitis resolution with optical coherence tomography.
    Optometry and vision science : official publication of the American Academy of Optometry, 2014, Volume: 91, Issue:4 Suppl 1

    Topics: Adult; Corneal Edema; Corneal Pachymetry; Corneal Stroma; Drug Therapy, Combination; Glucocorticoids

2014
Oral steroid therapy as an adjuvant treatment for severe epidemic keratoconjunctivitis in patients younger than 3 years.
    Cornea, 2015, Volume: 34, Issue:2

    Topics: Adenovirus Infections, Human; Administration, Oral; Blepharoptosis; Chemotherapy, Adjuvant; Child, P

2015
In Vivo Confocal Microscopy Use in Endotheliitis.
    Optometry and vision science : official publication of the American Academy of Optometry, 2015, Volume: 92, Issue:12

    Topics: Acyclovir; Adult; Anti-Inflammatory Agents; Antiviral Agents; Corneal Edema; Drug Therapy, Combinati

2015
An association between systemic cyclosporine administration and development of acute bullous keratopathy in cats.
    Veterinary ophthalmology, 2016, Volume: 19 Suppl 1

    Topics: Animals; Anti-Inflammatory Agents; Cat Diseases; Cats; Corneal Edema; Cyclosporine; Female; Immunosu

2016
Long-Term Topical Ganciclovir and Corticosteroids Preserve Corneal Endothelial Function in Cytomegalovirus Corneal Endotheliitis.
    Cornea, 2016, Volume: 35, Issue:5

    Topics: Administration, Topical; Adult; Antiviral Agents; Aqueous Humor; Corneal Edema; Cytomegalovirus; Cyt

2016
Thermal Ocular Surface Injury from Cooking Oil: Delayed Onset Transient Corneal Infiltration and Myopic Shift.
    Korean journal of ophthalmology : KJO, 2016, Volume: 30, Issue:2

    Topics: Administration, Topical; Adult; Anti-Bacterial Agents; Burns, Chemical; Cooking; Corneal Edema; Corn

2016
Beware traumatic conjunctivitis: airbags can cause severe alkali eye injuries.
    Clinical & experimental ophthalmology, 2016, Volume: 44, Issue:8

    Topics: Accidents, Traffic; Aged; Air Bags; Anti-Bacterial Agents; Antioxidants; Ascorbic Acid; Burns, Chemi

2016
Acute Bilateral Toxic Endotheliitis Following Alcohol Consumption.
    Ocular immunology and inflammation, 2018, Volume: 26, Issue:2

    Topics: Acute Disease; Adult; Alcohol Drinking; Anti-Bacterial Agents; Cataract; Cataract Extraction; Cornea

2018
Descemet's stripping automated endothelial keratoplasty.
    Optometry and vision science : official publication of the American Academy of Optometry, 2008, Volume: 85, Issue:9

    Topics: Aged; Aged, 80 and over; Corneal Edema; Corneal Transplantation; Descemet Membrane; Endothelium, Cor

2008
Toxic anterior segment syndrome after cataract surgery.
    Journal of cataract and refractive surgery, 2010, Volume: 36, Issue:2

    Topics: Aged; Anterior Eye Segment; Corneal Edema; Drug Therapy, Combination; Endotoxins; Female; Humans; Ke

2010
Amantadine-associated corneal edema.
    Parkinsonism & related disorders, 2010, Volume: 16, Issue:6

    Topics: Aged; Amantadine; Anti-Inflammatory Agents; Antiparkinson Agents; Corneal Edema; Female; Humans; Oph

2010
Severe corneal changes following intravitreal injection of bevacizumab.
    Ocular immunology and inflammation, 2010, Volume: 18, Issue:4

    Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Hu

2010
Presumed corneal stromal graft rejection after deep anterior lamellar keratoplasty in a patient with systemic lupus erythematosis.
    Eye & contact lens, 2010, Volume: 36, Issue:6

    Topics: Adolescent; Aza Compounds; Cornea; Corneal Edema; Corneal Stroma; Corneal Transplantation; Drug Admi

2010
Atypical presentation of cytomegalovirus endotheliitis: a case report.
    Ocular immunology and inflammation, 2011, Volume: 19, Issue:1

    Topics: Acyclovir; Aged; Antiviral Agents; Corneal Edema; Cytomegalovirus; Cytomegalovirus Infections; DNA,

2011
Long-term outcomes of penetrating keratoplasty for keratoconus with resolved corneal hydrops.
    Cornea, 2012, Volume: 31, Issue:6

    Topics: Corneal Edema; Drug Therapy, Combination; Female; Fluorocarbons; Follow-Up Studies; Glucocorticoids;

2012
Stromal rejection following deep anterior lamellar keratoplasty: implications for postoperative care.
    Cornea, 2012, Volume: 31, Issue:9

    Topics: Administration, Topical; Adolescent; Adult; Corneal Edema; Corneal Neovascularization; Corneal Strom

2012
Uveitis exacerbation after varicella-zoster vaccination in an adult.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2012, Volume: 130, Issue:6

    Topics: Acyclovir; Aged, 80 and over; Antiviral Agents; Cell Count; Corneal Edema; Drug Therapy, Combination

2012
[Corneal toxicity due to amantadine].
    Archivos de la Sociedad Espanola de Oftalmologia, 2012, Volume: 87, Issue:9

    Topics: Acyclovir; Amantadine; Antiparkinson Agents; Aqueous Humor; Cataract Extraction; Ceftazidime; Cornea

2012
Red eyes, reduced vision, and vomiting.
    Postgraduate medical journal, 2003, Volume: 79, Issue:935

    Topics: Aged; Anti-Inflammatory Agents; Corneal Edema; Female; Glaucoma, Angle-Closure; Humans; Miotics; Nau

2003
Severe late-onset recurrent epithelial erosion with diffuse lamellar keratitis after laser in situ keratomileusis.
    Journal of cataract and refractive surgery, 2003, Volume: 29, Issue:10

    Topics: Adult; Cornea; Corneal Edema; Epithelial Cells; Female; Glucocorticoids; Humans; Keratitis; Keratomi

2003
Effect of flap hinge placement on post-laser in situ keratomileusis wound healing in the presence of superior corneal vascularization.
    Journal of cataract and refractive surgery, 2003, Volume: 29, Issue:12

    Topics: Adult; Anti-Infective Agents; Corneal Edema; Corneal Neovascularization; Corneal Stroma; Corneal Top

2003
Bilateral phacofragmentation in a New Zealand fur seal (Arctocephalus forsteri).
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2004, Volume: 35, Issue:1

    Topics: Animals; Atropine; Cataract Extraction; Corneal Edema; Corneal Ulcer; Fur Seals; Male; Mydriatics; P

2004
Presumed stromal graft rejection after deep anterior lamellar keratoplasty.
    Cornea, 2005, Volume: 24, Issue:2

    Topics: Adolescent; Corneal Edema; Corneal Neovascularization; Corneal Stroma; Corneal Transplantation; Fema

2005
Uveitis-associated flap edema and lamellar interface fluid collection after LASIK.
    American journal of ophthalmology, 2005, Volume: 139, Issue:6

    Topics: Acute Disease; Body Fluids; Corneal Edema; Corneal Stroma; Female; Glucocorticoids; Humans; Hyperopi

2005
Late-onset interface inflammation associated with wearing cosmetic lenses 18 months after laser in situ keratomileusis.
    Cornea, 2008, Volume: 27, Issue:2

    Topics: Adult; Aza Compounds; Contact Lenses; Corneal Edema; Drug Therapy, Combination; Female; Fluoroquinol

2008
Glaucomatocyclitic crisis in a child.
    American journal of ophthalmology, 1998, Volume: 126, Issue:1

    Topics: Adolescent; Clonidine; Corneal Edema; Diagnosis, Differential; Drug Therapy, Combination; Glaucoma;

1998
Interface fluid after laser in situ keratomileusis.
    Journal of cataract and refractive surgery, 2001, Volume: 27, Issue:9

    Topics: Administration, Topical; Anti-Inflammatory Agents; Body Fluids; Cornea; Corneal Edema; Glucocorticoi

2001
Progression to end-stage glaucoma after laser in situ keratomileusis.
    Journal of cataract and refractive surgery, 2002, Volume: 28, Issue:2

    Topics: Adult; Corneal Edema; Disease Progression; Glaucoma; Glucocorticoids; Humans; Intraocular Pressure;

2002
Corneal neovascularisation in acute hydrops.
    Eye (London, England), 1992, Volume: 6 ( Pt 4)

    Topics: Adolescent; Adult; Corneal Edema; Corneal Neovascularization; Dexamethasone; Female; Humans; Keratoc

1992
Therapeutic response of herpes simplex virus-induced corneal edema to trifluridine in combination with immunosuppressive agents.
    Investigative ophthalmology & visual science, 1991, Volume: 32, Issue:9

    Topics: Animals; Cornea; Corneal Edema; Drug Combinations; Herpes Simplex; Immunosuppressive Agents; Male; P

1991
Topical nonsteroidal agents and corneal wound healing.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1990, Volume: 108, Issue:4

    Topics: Administration, Topical; Analysis of Variance; Animals; Collagen; Cornea; Corneal Edema; Corneal Inj

1990