prednisolone and Complication, Postoperative studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Research Excerpts

Excerpt	Relevance	Reference
"Difluprednate administered twice a day was at least as effective as prednisolone acetate administered 4 times a day for inflammatory treatment after cataract surgery."	9.51	Difluprednate 0.05% twice a day vs prednisolone acetate 1% 4 times a day for cataract postsurgical inflammation treatment: noninferiority trial. ( Del Papa, M; Ferroni, C; Ferroni, V; Idiart, C; Kaufer, R; Marino, F; Masseroni, M; Nuñez, M; Passerini, MS; Valvecchia, G; Zaldívar, R, 2022)
"1% nepafenac and 1% prednisolone acetate eye drop in postoperative inflammation control in micro-incisional cataract surgery."	9.41	Comparison between 0.1% Nepafenac and 1% Prednisolone Eye Drop in Postoperative Management Following Micro-incisional Cataract Surgery. ( Bardoloi, N; Deb, AK; Sarkar, S, 2021)
"Participants scheduled for cataract removal were randomized to 1 of 5 anti-inflammatory prophylactic regimens: eye drops with a combination of prednisolone, 1%, and ketorolac tromethamine, 0."	9.41	Prednisolone and Ketorolac vs Ketorolac Monotherapy or Sub-Tenon Prophylaxis for Macular Thickening in Cataract Surgery: A Randomized Clinical Trial. ( Erichsen, JH; Forman, JL; Forslund Jacobsen, M; Holm, LM; Kessel, L, 2021)
"5% with prednisolone acetate suspension (PA) 1% for the treatment of inflammation after cataract surgery in children."	9.34	Loteprednol etabonate gel 0.5% vs prednisolone acetate suspension 1% for the treatment of inflammation after cataract surgery in children. ( Vittitow, JL; Williams, JI, 2020)
"Addition of topical nepafenac eye drops to topical steroid drops significantly reduced the amount of pseudophakic macular edema after cataract surgery in high-risk eyes."	9.30	Efficacy of addition of nepafenac 0.1% to steroid eye drops in prevention of post-phaco macular edema in high-risk eyes. ( Abu Eleinen, KG; Darwish, EA; El Gharbawy, SA; Osman, MH, 2019)
"The results indicate that equivalent control of inflammation can be obtained through treatment with loteprednol etabonate or prednisolone acetate after cataract surgery."	9.17	Loteprednol etabonate 0.5% versus prednisolone acetate 1.0% for the treatment of inflammation after cataract surgery. ( Holland, EJ; Lane, SS, 2013)
"To compare the effects of preoperative use of topical anti-inflammatory prednisolone acetate, ketorolac tromethamine, nepafenac and placebo, on the maintenance of intraoperative mydriasis during cataract surgery."	9.16	Effect of preoperative use of topical prednisolone acetate, ketorolac tromethamine, nepafenac and placebo, on the maintenance of intraoperative mydriasis during cataract surgery: a randomized trial. ( Arieta, CE; Chaves, FR; da Costa Pinto, AP; Fulco, EA; Lira, RP; Zanetti, FR, 2012)
"To compare orbital floor triamcinolone acetonide and oral prednisolone in cataract surgery in patients with chronic non-infectious uveitis with regard to visual outcome, postoperative inflammation and macular edema."	9.14	Comparison of orbital floor triamcinolone acetonide and oral prednisolone for cataract surgery management in patients with non-infectious uveitis. ( Heiligenhaus, A; Heinz, C; Koch, JM; Roesel, M, 2010)
"The aim of this study was to evaluate the efficacy and safety of rimexolone 1% ophthalmic suspension compared to that of 1% prednisolone acetate in the control of inflammation in eyes undergoing cataract extraction with phacoemulsification followed by posterior chamber intraocular lens implantation."	9.11	Efficacy and safety of rimexolone 1% versus prednisolone acetate 1% in the control of postoperative inflammation following phacoemulsification cataract surgery. ( Ozbay, D; Ozden, S; Tatlipinar, S; Yaylali, V; Yildirim, C, 2004)
"To compare the efficacy and ocular adverse effects of topical prednisolone acetate, ketorolac tromethamine, and fluorometholone acetate in reducing inflammation after phacoemulsification."	9.10	Comparison of topical prednisolone acetate, ketorolac tromethamine and fluorometholone acetate in reducing inflammation after phacoemulsification. ( Atchaneeyasakul, LO; Kosrirukvongs, P; Surachatkumtonekul, T; Trinavarat, A, 2003)
"The diclofenac- and prednisolone-treated eyes were compared on postoperative days 3 and 7 with respect to signs of inflammation (e."	9.08	A randomized clinical trial of the nonsteroidal eyedrop diclofenac after strabismus surgery. ( Apt, L; Isenberg, SJ; Voo, I, 1998)
"In this large study of cataract surgery patients, a small statistically significant association of combination treatment compared with prednisolone alone was observed."	8.02	Visual outcomes after cataract surgery: topical nonsteroidal anti-inflammatory drug prophylaxis compared with prednisolone. ( Alexeeff, SE; Amsden, LB; Carolan, J; Herrinton, LJ; Liu, L; Shorstein, NH, 2021)
"To compare intraocular pressure (IOP) outcomes between 2 common, commercially available corticosteroid drops: difluprednate ophthalmic emulsion 0."	7.85	Comparison of prednisolone acetate 1.0% and difluprednate ophthalmic emulsion 0.05% after cataract surgery: Incidence of postoperative steroid-induced ocular hypertension. ( Ernest, P; McBain, M; Mian, SI; Musch, DC; Niziol, LM; Person, E; Tijunelis, MA, 2017)
"This study aimed to investigate the benefits of administering perioperative high-dose prednisolone in conjunction with thymectomy in patients with myasthenia gravis."	7.79	Efficacy of perioperative high-dose prednisolone therapy during thymectomy in myasthenia gravis patients. ( Iwata, T; Kawaguchi, N; Mizobuchi, T; Suzuki, H; Tagawa, T; Yamada, Y; Yoshida, S; Yoshino, I, 2013)
" Our objective is to evaluate the effectiveness of ciprofloxacin in the prevention of myringosclerosis that is created by myringotomy in rats and to compare it with prednisolone."	7.78	Evaluation of the effectiveness of topical ciprofloxacin and prednisolone in the prevention of myringosclerosis. ( Arslan, N; Caydere, M; Demirci, M; Oguz, H; Taştan, E; Tepe, D; Ustun, H, 2012)
"To evaluate the effect of a biodegradable microfilm with sustained release of prednisolone acetate (PA) on postoperative wound healing after experimental glaucoma filtration surgery (GFS)."	7.77	Evaluation of sustained release of PLC-loaded prednisolone acetate microfilm on postoperative inflammation in an experimental model of glaucoma filtration surgery. ( Ang, M; Foo, S; Venkatraman, SS; Wong, TT; Yan, P; Zhen, M, 2011)
"Here we describe a case of biopsy proven interstitial nephritis after moxifloxacin treatment."	7.76	Biopsy proven acute interstitial nephritis after treatment with moxifloxacin. ( Becker, J; Chatzikyrkou, C; Clajus, C; Hafer, C; Hamwi, I; Kielstein, JT, 2010)
"To compare the incidence of visually significant pseudophakic macular edema after uneventful phacoemulsification in patients treated postoperatively with topical prednisolone and those treated with topical prednisolone and nepafenac 0."	7.74	Incidence of visually significant pseudophakic macular edema after uneventful phacoemulsification in patients treated with nepafenac. ( Braunstein, A; Braunstein, RE; Shih, C; Wolf, EJ, 2007)
"After topical and intracameral application of amphotericin B in combination with topical prednisolone 3 months after the onset of the endophthalmitis, the infection disappeared within 14 days, and the graft remained clear for 2 months."	7.73	Amphotericin B in the therapy of Candida glabrata endophthalmitis after penetrating keratoplasty. ( Grueb, M; Rohrbach, JM; Zierhut, M, 2006)
"Increased prednisolone dose and older age are strongly associated with the development of posttransplant glucose intolerance."	7.69	Glucose intolerance after renal transplantation depends upon prednisolone dose and recipient age. ( Egeland, T; Fauchald, P; Hartmann, A; Hjelmesaeth, J; Kofstad, J; Leivestad, T; Stenstrøm, J, 1997)
"We reviewed the records of 12 eyes of ten adult patients with inflammatory glaucoma who underwent trabeculectomy with the adjuvant use of 5-fluorouracil between January 1986 and January 1989."	7.68	Trabeculectomy with 5-fluorouracil for adult inflammatory glaucoma. ( Jabs, DA; Jampel, HD; Quigley, HA, 1990)
"Rat recipients of renal allografts and unilaterally nephrectomized control rats were studied to evaluate the response in blood pressure to prednisolone in diverse doses, and to determine the dosage required to achieve adequate immunosuppression without undue complication of hypertension."	7.67	Prednisolone and posttransplantation hypertension in rat renal allograft recipients. ( de Keijzer, MH; Molenaar, JC; Provoost, AP; Van Aken, M; Wolff, ED, 1987)
"Tacrolimus monotherapy is a viable immunosuppressive strategy in HCV-infected liver transplant recipients."	6.72	Rejection rates in a randomised trial of tacrolimus monotherapy versus triple therapy in liver transplant recipients with hepatitis C virus cirrhosis. ( Burroughs, AK; Davidson, BR; Dhillon, AP; Leandro, G; Mela, M; Patch, DW; Pesci, A; Quaglia, A; Raimondo, ML; Rolles, K; Samonakis, DN; Thalheimer, U; Triantos, CK, 2006)
"In pediatric cataracts, outcomes were better with PST tricort and the adjunctive I/C tricort compared to postoperative topical prednisolone, for modulating postoperative inflammation."	5.69	Comparison of topical steroids versus adjunctive intracameral triamcinolone versus posterior subtenon triamcinolone in pediatric cataract surgery. ( Bhattacharya, S; Pavitra, B; Raina, UK; Ravinesh, K; Thakar, M, 2023)
"Difluprednate administered twice a day was at least as effective as prednisolone acetate administered 4 times a day for inflammatory treatment after cataract surgery."	5.51	Difluprednate 0.05% twice a day vs prednisolone acetate 1% 4 times a day for cataract postsurgical inflammation treatment: noninferiority trial. ( Del Papa, M; Ferroni, C; Ferroni, V; Idiart, C; Kaufer, R; Marino, F; Masseroni, M; Nuñez, M; Passerini, MS; Valvecchia, G; Zaldívar, R, 2022)
"Prevention of cystoid macular edema (CME) is important to achieve good surgical outcomes after cataract surgery."	5.48	Prednisolone versus dexamethasone for prevention of pseudophakic cystoid macular edema. ( Baartman, BJ; Gans, R; Goshe, J, 2018)
"1% nepafenac and 1% prednisolone acetate eye drop in postoperative inflammation control in micro-incisional cataract surgery."	5.41	Comparison between 0.1% Nepafenac and 1% Prednisolone Eye Drop in Postoperative Management Following Micro-incisional Cataract Surgery. ( Bardoloi, N; Deb, AK; Sarkar, S, 2021)
"Participants scheduled for cataract removal were randomized to 1 of 5 anti-inflammatory prophylactic regimens: eye drops with a combination of prednisolone, 1%, and ketorolac tromethamine, 0."	5.41	Prednisolone and Ketorolac vs Ketorolac Monotherapy or Sub-Tenon Prophylaxis for Macular Thickening in Cataract Surgery: A Randomized Clinical Trial. ( Erichsen, JH; Forman, JL; Forslund Jacobsen, M; Holm, LM; Kessel, L, 2021)
"Fungal endophthalmitis is a destructive intraocular infection resulting in poor visual prognosis."	5.38	Post-operative endophthalmitis due to Fusarium dimerum. ( Dinesh, K; Karim, PM; Khan, S; Pillai, GS; Vivek, V, 2012)
"Oral prednisolone was started with 0."	5.37	Effect of oral prednisolone on esophageal stricture after complete circular endoscopic submucosal dissection for superficial esophageal squamous cell carcinoma: a case report. ( Hayashi, T; Isomoto, H; Kohno, S; Nakao, K; Nakayama, T; Ohnita, K; Shikuwa, S; Takeshima, F; Yamaguchi, N, 2011)
"5% with prednisolone acetate suspension (PA) 1% for the treatment of inflammation after cataract surgery in children."	5.34	Loteprednol etabonate gel 0.5% vs prednisolone acetate suspension 1% for the treatment of inflammation after cataract surgery in children. ( Vittitow, JL; Williams, JI, 2020)
"Addition of topical nepafenac eye drops to topical steroid drops significantly reduced the amount of pseudophakic macular edema after cataract surgery in high-risk eyes."	5.30	Efficacy of addition of nepafenac 0.1% to steroid eye drops in prevention of post-phaco macular edema in high-risk eyes. ( Abu Eleinen, KG; Darwish, EA; El Gharbawy, SA; Osman, MH, 2019)
"Patients with non-viral infections seemed to have more depressed lymphocyte responses than non-infected patients."	5.27	Immunological recovery after bone marrow transplantation: role of age, graft-versus-host disease, prednisolone treatment and infections. ( Nilsson, B; Paulin, T; Ringdén, O, 1987)
"The results indicate that equivalent control of inflammation can be obtained through treatment with loteprednol etabonate or prednisolone acetate after cataract surgery."	5.17	Loteprednol etabonate 0.5% versus prednisolone acetate 1.0% for the treatment of inflammation after cataract surgery. ( Holland, EJ; Lane, SS, 2013)
"To compare the effects of preoperative use of topical anti-inflammatory prednisolone acetate, ketorolac tromethamine, nepafenac and placebo, on the maintenance of intraoperative mydriasis during cataract surgery."	5.16	Effect of preoperative use of topical prednisolone acetate, ketorolac tromethamine, nepafenac and placebo, on the maintenance of intraoperative mydriasis during cataract surgery: a randomized trial. ( Arieta, CE; Chaves, FR; da Costa Pinto, AP; Fulco, EA; Lira, RP; Zanetti, FR, 2012)
"To compare orbital floor triamcinolone acetonide and oral prednisolone in cataract surgery in patients with chronic non-infectious uveitis with regard to visual outcome, postoperative inflammation and macular edema."	5.14	Comparison of orbital floor triamcinolone acetonide and oral prednisolone for cataract surgery management in patients with non-infectious uveitis. ( Heiligenhaus, A; Heinz, C; Koch, JM; Roesel, M, 2010)
"A single posterior subtenon injection of TA can be as effective and safe as a 4-week regimen of prednisolone acetate 1% eyedrops in controlling intraocular inflammation after PPV."	5.12	Anti-inflammatory efficacy of a single posterior subtenon injection of triamcinolone acetonide versus prednisolone acetate 1% eyedrops after pars plana vitrectomy. ( Barbosa, JC; Costa, RA; Jorge, R; Paccola, L; Scott, IU, 2007)
"The aim of this study was to evaluate the efficacy and safety of rimexolone 1% ophthalmic suspension compared to that of 1% prednisolone acetate in the control of inflammation in eyes undergoing cataract extraction with phacoemulsification followed by posterior chamber intraocular lens implantation."	5.11	Efficacy and safety of rimexolone 1% versus prednisolone acetate 1% in the control of postoperative inflammation following phacoemulsification cataract surgery. ( Ozbay, D; Ozden, S; Tatlipinar, S; Yaylali, V; Yildirim, C, 2004)
" We sought to test the hypothesis that tapering of prednisolone (TAP) the first year after renal transplantation improves insulin sensitivity (IS), and to assess the effect of complete steroid withdrawal (SW) on IS in patients on a cyclosporine-based immunosuppressive regimen."	5.11	Insulin resistance after renal transplantation: the effect of steroid dose reduction and withdrawal. ( Egeland, T; Hartmann, A; Hjelmesaeth, J; Jenssen, T; Lund, K; Midtvedt, K; Paulsen, D, 2004)
"To compare the efficacy and ocular adverse effects of topical prednisolone acetate, ketorolac tromethamine, and fluorometholone acetate in reducing inflammation after phacoemulsification."	5.10	Comparison of topical prednisolone acetate, ketorolac tromethamine and fluorometholone acetate in reducing inflammation after phacoemulsification. ( Atchaneeyasakul, LO; Kosrirukvongs, P; Surachatkumtonekul, T; Trinavarat, A, 2003)
"In the diclofenac group (n = 14), the preoperative intraocular pressure of 30."	5.08	The efficacy and safety of diclofenac 0.1% versus prednisolone acetate 1% following trabeculectomy with adjunctive mitomycin-C. ( Cate, EA; Dubiner, HB; Kent, AR; Mundorf, TK; Stewart, JA; Stewart, WC; Whitaker, R, 1998)
"The diclofenac- and prednisolone-treated eyes were compared on postoperative days 3 and 7 with respect to signs of inflammation (e."	5.08	A randomized clinical trial of the nonsteroidal eyedrop diclofenac after strabismus surgery. ( Apt, L; Isenberg, SJ; Voo, I, 1998)
" From March 1979 to November 1981 a randomised controlled trial of high (33 patients) v low oral dose (34 patients) of prednisolone along with azathioprine was conducted in recipients of first cadaveric transplants who had received a blood transfusion within six months of transplantation."	5.05	High versus "low" dose corticosteroids in recipients of cadaveric kidneys: prospective controlled trial. ( Adu, D; Bewick, M; Brown, CB; Cameron, JS; Donaghey, R; Ogg, CS; Papadakis, J; Rudge, C; Taube, D; Williams, DG, 1983)
"Both prednisolone and papase are effective in reducing the oral surgical sequelae of trismus and pain, although prednisolone apparently is the more potent drug."	5.04	Double-blind study of prednisolone and papase as inhibitors of complications after oral surgery. ( Caci, F; Gluck, GM, 1976)
"To compare the safety and efficacy of topical prednisolone and intracanalicular dexamethasone ophthalmic insert for the prevention of postoperative inflammation after cataract surgery."	4.12	Safety and efficacy of topical vs intracanalicular corticosteroids for the prevention of postoperative inflammation after cataract surgery. ( Goodling, K; Lehman, E; Lu, AQ; O'Rourke, T; Pantanelli, SM; Rizk, M; Scott, IU, 2022)
"Four eyes of four patients developed TASS associated with formaldehyde after uneventful primary pterygium surgery with conjunctival autograft."	4.12	Cases of toxic anterior segment syndrome after primary pterygium surgery. ( Gümüş, G; Kara, N; Karatas Durusoy, G; Öcal, MC, 2022)
"In this large study of cataract surgery patients, a small statistically significant association of combination treatment compared with prednisolone alone was observed."	4.02	Visual outcomes after cataract surgery: topical nonsteroidal anti-inflammatory drug prophylaxis compared with prednisolone. ( Alexeeff, SE; Amsden, LB; Carolan, J; Herrinton, LJ; Liu, L; Shorstein, NH, 2021)
"Stress-induced hyperlactatemia and subsequent myasthenic crisis INTERVENTIONS:: Pyridostigmine and immunosuppressive therapy with prednisolone were initiated."	3.96	Myasthenic crisis and late deep vein thrombosis following thymectomy in a patient with myasthenia gravis: A case report. ( Chen, JY; Cheng, WJ; Chiang, MH; Chu, CC; Ho, CN; Hung, KC; Liao, SW; Lin, CY; Liu, WC; Sun, CK; Tsai, IT, 2020)
" Those who received intralesional triamcinolone injection combined with oral prednisolone administration were assigned to the treatment group, while those who were treated without any prophylaxis of esophageal stricture were assigned to the control group."	3.91	Long-term efficacy and safety of intralesional steroid injection plus oral steroid administration in preventing stricture after endoscopic submucosal dissection for esophageal epithelial neoplasms. ( Chen, T; Chen, W; Chu, Y; Li, H; Xu, M; Yao, L; Zhang, Y; Zhong, Y; Zhou, P, 2019)
"To compare intraocular pressure (IOP) outcomes between 2 common, commercially available corticosteroid drops: difluprednate ophthalmic emulsion 0."	3.85	Comparison of prednisolone acetate 1.0% and difluprednate ophthalmic emulsion 0.05% after cataract surgery: Incidence of postoperative steroid-induced ocular hypertension. ( Ernest, P; McBain, M; Mian, SI; Musch, DC; Niziol, LM; Person, E; Tijunelis, MA, 2017)
" Prophylactic steroid protocol consisted of 2 weeks oral prednisolone (1 mg/kg/day) initiated immediately after the procedure, and in the event of bradyarrhythmia it was escalated to 2 mg/kg."	3.83	Transcatheter device closure of perimembranous ventricular septal defect in children treated with prophylactic oral steroids: acute and mid-term results of a single-centre, prospective, observational study. ( Bhalodiya, D; Bohora, S; Madan, T; Patel, N; Poptani, V; Shah, S; Shukla, A; Singh, T; Thakkar, B, 2016)
"This study aimed to investigate the benefits of administering perioperative high-dose prednisolone in conjunction with thymectomy in patients with myasthenia gravis."	3.79	Efficacy of perioperative high-dose prednisolone therapy during thymectomy in myasthenia gravis patients. ( Iwata, T; Kawaguchi, N; Mizobuchi, T; Suzuki, H; Tagawa, T; Yamada, Y; Yoshida, S; Yoshino, I, 2013)
" Our objective is to evaluate the effectiveness of ciprofloxacin in the prevention of myringosclerosis that is created by myringotomy in rats and to compare it with prednisolone."	3.78	Evaluation of the effectiveness of topical ciprofloxacin and prednisolone in the prevention of myringosclerosis. ( Arslan, N; Caydere, M; Demirci, M; Oguz, H; Taştan, E; Tepe, D; Ustun, H, 2012)
"A 64 year-old female with Parkinson disease treated with amantadine for two years who suddenly suffered bilateral corneal oedema."	3.78	[Corneal toxicity due to amantadine]. ( Avendaño-Cantos, EM; Celis-Sánchez, J; Gálvez-Martínez, J; González Del Valle, F; López-Arroquia, E; Mesa-Varona, D, 2012)
"To evaluate the effect of a biodegradable microfilm with sustained release of prednisolone acetate (PA) on postoperative wound healing after experimental glaucoma filtration surgery (GFS)."	3.77	Evaluation of sustained release of PLC-loaded prednisolone acetate microfilm on postoperative inflammation in an experimental model of glaucoma filtration surgery. ( Ang, M; Foo, S; Venkatraman, SS; Wong, TT; Yan, P; Zhen, M, 2011)
" Despite continued allopurinol therapy the gouty arthritis of the peripheral joints re-occurred."	3.76	[Fever and back pain--a case report of spinal gout]. ( Behr, C; Schorn, C; Schwarting, A, 2010)
"Here we describe a case of biopsy proven interstitial nephritis after moxifloxacin treatment."	3.76	Biopsy proven acute interstitial nephritis after treatment with moxifloxacin. ( Becker, J; Chatzikyrkou, C; Clajus, C; Hafer, C; Hamwi, I; Kielstein, JT, 2010)
"An 84-year-old woman under warfarin therapy, who had undergone mechanical valve replacement 29 months previously, developed coagulation abnormalities after antibiotic treatment for pyelonephritis."	3.76	Acquired factor V inhibitor in a patient with a mechanical aortic valve under warfarin therapy. ( Mita, H; Nozu, T; Okumura, T, 2010)
"To compare the incidence of visually significant pseudophakic macular edema after uneventful phacoemulsification in patients treated postoperatively with topical prednisolone and those treated with topical prednisolone and nepafenac 0."	3.74	Incidence of visually significant pseudophakic macular edema after uneventful phacoemulsification in patients treated with nepafenac. ( Braunstein, A; Braunstein, RE; Shih, C; Wolf, EJ, 2007)
"Intravenous therapy with prednisolone, hydroxyethyl starch 3% and pentoxifylline in the acute postoperative period does not improve hearing in patients who develop acute deafness after attempted hearing preservation surgery for AN."	3.73	Steroid and vasoactive treatment for acute deafness after attempted hearing preservation acoustic neuroma surgery. ( Gouveris, H; Mann, W; Maurer, J; Mewes, T, 2005)
"After topical and intracameral application of amphotericin B in combination with topical prednisolone 3 months after the onset of the endophthalmitis, the infection disappeared within 14 days, and the graft remained clear for 2 months."	3.73	Amphotericin B in the therapy of Candida glabrata endophthalmitis after penetrating keratoplasty. ( Grueb, M; Rohrbach, JM; Zierhut, M, 2006)
" Postoperative uveitis was controlled with oral prednisolone."	3.72	Bilateral phacofragmentation in a New Zealand fur seal (Arctocephalus forsteri). ( Barnes, JA; Smith, JS, 2004)
" Histology and immunofluorescence confirmed a clinical diagnosis of bullous pemphigoid and her condition resolved rapidly after treatment with prednisolone."	3.71	Development of a bullous pemphigoid after split-skin grafting. ( Ghura, HS; Johnston, GA; Milligan, A, 2001)
"We report 2 cases of thymomatous myasthenia gravis associated with postoperative crisis and medicated with steroid therapy using prednisolone without primary dose escalation."	3.71	Steroid therapy without primary dose escalation for postthymectomy crisis in 2 thymomatous myasthenia gravis patients. ( Fujiwara, K; Hasegawa, K; Inoue, M; Kimura, K; Nakagawa, K; Yasumitsu, T, 2002)
"To assess the effect of intensive topical and intravenous antibiotics plus oral prednisolone and surgical debridement in Pseudomonas keratoscleritis after pterygium excision."	3.70	The treatment of Pseudomonas keratoscleritis after pterygium excision. ( Huang, SC; Lai, HC; Lai, IC, 1999)
" She presented with bilateral hilar lymphadenopathy, left-sided lower cranial nerve palsies (8th, 9th, and 10th), and vestibular ataxia, which improved following the administration of prednisolone."	3.69	Neurosarcoidosis following augmentation mammoplasty with silicone. ( Hirai, S; Okamoto, K; Tanaka, M; Yoshida, T, 1996)
"Increased prednisolone dose and older age are strongly associated with the development of posttransplant glucose intolerance."	3.69	Glucose intolerance after renal transplantation depends upon prednisolone dose and recipient age. ( Egeland, T; Fauchald, P; Hartmann, A; Hjelmesaeth, J; Kofstad, J; Leivestad, T; Stenstrøm, J, 1997)
"We reviewed the records of 12 eyes of ten adult patients with inflammatory glaucoma who underwent trabeculectomy with the adjuvant use of 5-fluorouracil between January 1986 and January 1989."	3.68	Trabeculectomy with 5-fluorouracil for adult inflammatory glaucoma. ( Jabs, DA; Jampel, HD; Quigley, HA, 1990)
"One hundred and ninety-two patients received 200 consecutive cadaver renal transplants (158 first and 42 regrafts) and were treated with triple therapy immunosuppression consisting of low-dose cyclosporin, azathioprine and prednisolone."	3.68	Triple therapy immunosuppression in cadaveric renal transplantation. ( Higgins, RM; Morris, PJ; Murie, J; Ratcliffe, PJ; Richardson, AJ; Ting, A, 1990)
"Eleven patients, who had undergone renal transplantation and who had hypertension, aged 19-56 years, were treated with cyclosporine and prednisolone."	3.67	Renin-angiotensin-aldosterone system and vasopressin in cyclosporine-treated renal allograft recipients. ( Kovarik, J; Rasoul-Rockenschaub, S; Silberbauer, K; Stanek, B, 1987)
"Rat recipients of renal allografts and unilaterally nephrectomized control rats were studied to evaluate the response in blood pressure to prednisolone in diverse doses, and to determine the dosage required to achieve adequate immunosuppression without undue complication of hypertension."	3.67	Prednisolone and posttransplantation hypertension in rat renal allograft recipients. ( de Keijzer, MH; Molenaar, JC; Provoost, AP; Van Aken, M; Wolff, ED, 1987)
"Treatment with oral prednisolone appears to have precipitated an episode of ascending cholangitis in an asymptomatic 55-year-old patient."	3.67	Disseminated infection associated with corticosteroid therapy after transduodenal sphincteroplasty. ( Kirk, RM; Noone, P; Pounder, RE; Sharma, BK; Wilson, DW, 1985)
"The intraocular pressures were measured at regular intervals during the 6-months follow-up period."	2.80	Influence on intraocular pressure of anti-inflammatory treatments after selective laser trabeculoplasty. ( Anctil, JL; Champagne, S; Des Marchais, B; Goyette, A; Lajoie, C, 2015)
"The intraocular pressure was slightly higher in Group II (p<0."	2.78	Efficacy and tolerability of a gatifloxacin/prednisolone acetate fixed combination for topical prophylaxis and control of inflammation in phacoemulsification: a 20-day-double-blind comparison to its individual components. ( Avakian, A; Brasil, A; Cunha, PA; Shinzato, FA; Tecchio, GT; Weber, SL, 2013)
"Postoperative pain, facial swelling and trismus were evaluated."	2.75	The effect of prednisolone on reduction of complaints after impacted third molar removal. ( Leibur, E; Tamme, T; Tiigimae-Saar, J, 2010)
"Prednisolone was ineffective in early recovery from postparotidectomy FNP."	2.73	A prospective, randomized trial for use of prednisolone in patients with facial nerve paralysis after parotidectomy. ( Park, CI; Roh, JL, 2008)
"The rimexolone group was associated with significantly higher score for conjunctival hyperemia on days one and three (P < 0."	2.73	Rimexolone 1% versus prednisolone acetate in preventing early postoperative inflammation after cataract surgery. ( Ardagil, A; Erbil, HH; Horoz, H; Kavuncu, S, 2008)
"Tacrolimus monotherapy is a viable immunosuppressive strategy in HCV-infected liver transplant recipients."	2.72	Rejection rates in a randomised trial of tacrolimus monotherapy versus triple therapy in liver transplant recipients with hepatitis C virus cirrhosis. ( Burroughs, AK; Davidson, BR; Dhillon, AP; Leandro, G; Mela, M; Patch, DW; Pesci, A; Quaglia, A; Raimondo, ML; Rolles, K; Samonakis, DN; Thalheimer, U; Triantos, CK, 2006)
"Calcitriol has been shown to have immunomodulatory effects."	2.71	Reduction of immunosuppressant therapy requirement in heart transplantation by calcitriol. ( Briffa, NK; Eisman, JA; Keogh, AM; Sambrook, PN, 2003)
"The incidence of infections was comparable ( P>0."	2.70	Early steroid withdrawal in renal transplantation with tacrolimus dual therapy: a pilot study. ( Boots, JM; Christiaans, MH; Van Duijnhoven, EM; Van Hooff, JP; Van Suylen, RJ, 2002)
" No adverse events were reported, and there were no significant changes in intraocular pressure in either group."	2.69	Comparison of the efficacy and safety of ketorolac tromethamine 0.5% and prednisolone acetate 1% after cataract surgery. ( Jenkins, JE; Pendelton, RA; Simone, JN, 1999)
"In the dosage used, diclofenac was as effective an anti-inflammatory agent for uncomplicated post-cataract inflammation as prednisolone."	2.68	A comparison of topical diclofenac with prednisolone for postcataract inflammation. ( Brennan, KM; Roberts, CW, 1995)
"Thus diclofenac sodium was as effective an anti-inflammatory agent for postoperative inflammation as prednisolone acetate."	2.67	A comparison of topical non-steroidal anti-inflammatory drugs to steroids for control of post cataract inflammation. ( Brennan, KM; Brown, RM; Roberts, CW, 1993)
"Initial angiographic cystoid macular edema was comparable and significantly improved after therapy in the two treatment groups."	2.67	[Differential treatment of postoperative and uveitis-induced inflammatory cystoid macular edema]. ( Guex-Crosier, Y; Herbort, CP; Othenin-Girard, P, 1992)
"Randomised-controlled trials (RCTs) comparing difluprednate and prednisolone acetate regardless of the dosing regimen used."	2.61	Difluprednate versus Prednisolone Acetate after Cataract Surgery: a Systematic Review and Meta-Analysis. ( Basiony, A; KhalafAllah, MT; Salama, A, 2019)
"Diarrhea is a common clinical feature of inflammatory bowel diseases and may be accompanied by abdominal pain, urgency, and fecal incontinence."	2.48	Diarrhea in chronic inflammatory bowel diseases. ( Wenzl, HH, 2012)
"Sirolimus is a new agent related to tacrolimus, but its mechanism of action differs."	2.42	Sirolimus may not cause neurotoxicity in kidney and liver transplant recipients. ( Maramattom, BV; Wijdicks, EF, 2004)
"A case of Basedow's disease, that developed after successful treatment of ulcerative colitis with a total colectomy, is presented, along with a review of the Japanese literature on the coexistence of hyperthyroidism and ulcerative colitis."	2.41	Basedow's disease and chronic ulcerative colitis: a case report and review of the Japanese literature. ( Hada, T; Iijima, H; Moriwaki, Y; Nishimura, M; Takahashi, S; Yamamoto, T, 2001)
"The patient was given a diagnosis of refractory anemia with excess of blasts in transformation (RAEB in T), and treated with idarubicin and cytosine arabinoside."	2.40	[Myelodysplastic syndrome (RAEB in T) developed in a renal allograft recipient]. ( Akiyama, M; Inaba, T; Katori, Y; Maki, K; Nakagawa, M; Sawada, K; Shimazaki, C; Shiraishi, J; Sudo, Y; Takada, O, 1998)
"Cancer was less common in recipients with a higher BMI (hazard ratio (HR) 0."	1.48	Is big bad or bearable? Long-term renal transplant outcomes in obese recipients. ( Courtney, AE; Devine, PA; McCaughan, JA; McCloskey, OM, 2018)
"Prevention of cystoid macular edema (CME) is important to achieve good surgical outcomes after cataract surgery."	1.48	Prednisolone versus dexamethasone for prevention of pseudophakic cystoid macular edema. ( Baartman, BJ; Gans, R; Goshe, J, 2018)
"Prednisolone effect on MRE was assessed ex vivo in blood samples from nontransplanted controls."	1.48	Suppressed calcineurin-dependent gene expression identifies lung allograft recipients at increased risk of infection. ( Chong, T; Golden, JA; Greenland, JR; Hays, SR; Kukreja, J; Martinez, E; Shrestha, P; Singer, JP; Tang, Q; Wang, AS, 2018)
"Pyoderma gangrenosum is an intractable disease of unknown cause involving recurrent ulcerative lesions on the skin, and may accompany ulcerative colitis, rheumatoid arthritis, leukemia, systemic lupus erythematosus, and other conditions."	1.46	Pyoderma Gangrenosum after Breast Mastectomy and Primary Rectus Abdominis Flap Reconstruction. ( Akamatsu, T; Imagawa, K; Kumaki, N; Morioka, T; Niikura, N; Okamura, T; Suzuki, Y; Terao, M; Tokuda, Y; Tsuda, B; Yamada, E; Yokoyama, K, 2017)
"Even following transplantation, recurrence of PSC is seen in approximately one quarter of patients and leads to high rates of graft failure."	1.46	Efficacy of oral vancomycin in recurrent primary sclerosing cholangitis following liver transplantation. ( Gow, P; Hey, P; Johnson, P; Lokan, J, 2017)
"Pyoderma gangrenosum is an inflammatory, ulcerative, neutrophilic dermatosis that is clinically characterized by rapidly evolving, painful, necrotic skin lesions."	1.46	[Pyoderma gangraenosum after implantation of a shoulder endoprothesis]. ( Anderl, W; Domej, MA; Heuberer, PR; Pauzenberger, L, 2017)
"Patients with type 1 diabetes, who had received a kidney transplant previously, were treated with alemtuzumab as induction therapy for their first islet transplantation and basiliximab induction therapy for subsequent islet transplantations."	1.43	Glycemic Stability Through Islet-After-Kidney Transplantation Using an Alemtuzumab-Based Induction Regimen and Long-Term Triple-Maintenance Immunosuppression. ( Bouwsma, H; Braat, AE; de Fijter, JW; de Koning, EJ; Dubbeld, J; Engelse, MA; Nijhoff, MF; Rabelink, TJ; Ringers, J; Roelen, DL; Spijker, HS; van der Boog, PJ; van Erkel, AR, 2016)
"Osteoporosis was defined as a bone densitometry T score of less than -2."	1.43	Longterm corticosteroid use after liver transplantation for autoimmune hepatitis is safe and associated with a lower incidence of recurrent disease. ( Gunson, BK; Hodson, J; Krishnamoorthy, TL; Miezynska-Kurtycz, J; Milkiewicz, P; Neuberger, J; Oo, YH, 2016)
"Bullous pemphigoid is a blistering disorder which can be idiopathic or arise secondary to drugs or trauma; however, blistering arising within surgical scars is rare."	1.43	Bullous Pemphigoid Arising in Lower Leg Vein Graft Incision Site. ( McKenna, K; Murphy, B; Walsh, M, 2016)
"To analyze the effect of intensified topical steroid therapy after Descemet membrane endothelial keratoplasty combined with cataract surgery (triple-DMEK) on the incidence of postoperative cystoid macular edema (CME)."	1.43	Intensified Topical Steroids as Prophylaxis for Macular Edema After Posterior Lamellar Keratoplasty Combined With Cataract Surgery. ( Bachmann, BO; Cursiefen, C; Felsch, M; Hoerster, R; Siebelmann, S; Stanzel, TP, 2016)
"A 17-year-old male patient with large syringomyelia extending from C2 - T2 level had a surgical procedure done under general anesthesia (GA) in prone position that lasted four hours."	1.43	A case of bilateral visual loss after spinal cord surgery. ( Abebe, W; Bekele, N; Habte, D; Shifa, J, 2016)
"An association between severe achalasia and arthritis has also been described, but very few articles on this topic are cited in PubMed, and most of the published case reports are old."	1.39	Remission of arthritis after esophagectomy in three patients with severe achalasia. ( Eriksson, P; Jacobs, C; Johansson, KE, 2013)
"We report a case of acquired hemophilia A (AHA) after esophageal resection."	1.39	Acquired hemophilia A caused by factor VIII inhibitors: report of a case. ( Hosoya, Y; Lefor, A; Madoiwa, S; Matsumoto, S; Matsumura, M; Nunomiya, S; Sata, N; Yasuda, Y; Zuiki, T, 2013)
"Fungal endophthalmitis is a destructive intraocular infection resulting in poor visual prognosis."	1.38	Post-operative endophthalmitis due to Fusarium dimerum. ( Dinesh, K; Karim, PM; Khan, S; Pillai, GS; Vivek, V, 2012)
"Common postoperative complications were cataract and graft infiltrate."	1.38	Long-term outcomes of penetrating keratoplasty for keratoconus with resolved corneal hydrops. ( Basu, S; Reddy, JC; Sangwan, VS; Vaddavalli, PK; Vemuganti, GK, 2012)
"Pyoderma gangrenosum is a rarely diagnosed autoimmune disease which often occurs after physical trauma such as surgical interventions."	1.38	[Multilocular pyoderma gangrenosum after uterus resection]. ( Al Ghazal, P; Dissemond, J, 2012)
"Oral prednisolone was started with 0."	1.37	Effect of oral prednisolone on esophageal stricture after complete circular endoscopic submucosal dissection for superficial esophageal squamous cell carcinoma: a case report. ( Hayashi, T; Isomoto, H; Kohno, S; Nakao, K; Nakayama, T; Ohnita, K; Shikuwa, S; Takeshima, F; Yamaguchi, N, 2011)
" Correlation between daily corticosteroid dosage and remission time and factors relating to final visual acuity of <20/40 were studied."	1.37	Central serous chorioretinopathy after renal transplantation. ( Byeon, SH; Kang, EC; Koh, HJ; Lee, CS; Lee, KS; Lee, SC, 2011)
"There was a significant positive correlation between the levels of MIF and the total preoperative dosage of prednisolone."	1.37	Neutrophil dysfunction in steroid-overdosed patients with ulcerative colitis: potential relevance of macrophage migration inhibitory factor to increased postoperative morbidity. ( Araki, T; Kusunoki, M; Miki, C; Okita, Y; Otake, K; Uchida, K; Yoshiyama, S, 2011)
"Sympathetic ophthalmia was diagnosed and systemic steroids together with azathioprine were initiated."	1.36	Sympathetic ophthalmia following vitreoretinal surgery. ( Arikan, G; Bajin, MS; Oner, H; Ozbek, Z; Saatci, AO; Yaman, A, 2010)
"Other postoperative complications were noted in eight, but with no fatal cases."	1.36	Evaluating patients' outcome post-Kasai operation: a 19-year experience with modification of the hepatic portoenterostomy and applying a novel steroid therapy regimen. ( Hashimoto, T; Hussein, MH; Kondo, S; Sato, Y; Suzuki, T, 2010)
"Data recorded were visual acuity (VA), recurrences and surgical complications."	1.36	[Pars plana vitrectomy as anti-inflammatory therapy for intermediate uveitis in children]. ( Arruabarrena, C; Contreras, I; Figueroa, MS; García-Pérez, JL; Gil-Cazorla, R; Noval, S; Sales, M, 2010)
"Systemic mastocytosis is a rare cause of vertebral fractures in young men."	1.35	Multimodal therapy for vertebral involvement of systemic mastocytosis. ( Brendel, C; Hamann, C; Hofbauer, LC; Krüger, A; Neubauer, A; Ramaswamy, A; Schnabel, M, 2009)
"Bacterial endophthalmitis is a potential complication of ICL implantation."	1.35	Culture-positive endophthalmitis after implantation of intraocular Collamer lens. ( Cohen, JA; Davis, MJ; Dennis, RF; Epstein, RJ, 2009)
"The major cause of ESRD was a congenital anomaly of the kidneys (53%)."	1.35	Pediatric renal transplantation: a single-center experience in northeast Thailand. ( Jiravuttipong, A; Wisanuyotin, S, 2009)
"Sirolimus treatment is beneficial for long-term graft survival."	1.35	Impact of sirolimus treatment in kidney allograft recipients with prolonged cold ischemia times: 5-year outcomes. ( Banasik, M; Boratynska, M; Klinger, M; Patrzalek, D, 2008)
"The patient developed facial palsy 9 days later, affecting all facial muscle groups equally."	1.34	Delayed facial palsy in a patient with a bifid facial nerve lending support for viral theory of facial palsy. ( Sheahan, P; Viani, L, 2007)
"Four patients developed orbital myositis following routine strabismus surgery."	1.34	Postoperative myositis in reoperated extraocular muscles. ( Archer, SM; Wolf, AB; Yang, MB, 2007)
"The histology was consistent with ulcerative colitis."	1.33	Development of ulcerative colitis after heart transplantation during immunosuppressive therapy. ( Böhm, M; Ecker, KW; Giese, T; Jüngling, B; Kindermann, I; Moser, C; Püschel, W; Schäfers, HJ; Stallmach, A; Zeuzem, S, 2005)
"During the past 10 years, acute disseminated encephalomyelitis has been reported a few times after organ transplantation."	1.33	Acute disseminated encephalomyelitis after liver transplantation. ( Gilani, A; Lindzen, E; Mann, D; Markovic-Plese, S, 2005)
" There was no significant difference between groups in terms of infection or serious adverse events."	1.33	Alemtuzumab (CAMPATH 1H) induction therapy in cadaveric kidney transplantation--efficacy and safety at five years. ( Bradley, JA; Bradley, JR; Calne, R; Firth, J; Friend, PJ; Hale, G; Jamieson, NV; Smith, KG; Taylor, CJ; Thiru, S; Waldmann, H; Watson, CJ, 2005)
"Laryngeal edema is considered a postoperative problem in phonosurgery."	1.33	[Experiences with intraoperative application of prednisolone during Isshiki type I thyroplasty]. ( Fleischer, S; Grundmann, T; Hess, M; Kothe, C; Schade, G, 2005)
" Type and dosage of immunosuppressive agents, pretransplant weight and human leukocyte antigen (HLA) phenotypes in PTDM patients were compared with 61 matched controls."	1.33	Is HLA-DR6 a protective factor against posttransplantation diabetes mellitus? ( Amjadi, H; Amouzegar, A; Einollahi, B; Firouzan, A; Hemati, K; Nafar, M; Pour-Reza-Gholi, F, 2005)
" A reduction in MPA dosage at the time of conversion may be necessary to prevent over-immunosuppression."	1.33	Conversion to everolimus in maintenance patients--current clinical strategies. ( Pohanka, E, 2006)
"His thymoma was not removed completely due to adhesion with other organs."	1.33	[A case of myasthenia gravis appearing after thymomectomy: with histopathological investigation]. ( Kusunoki, S; Miyamoto, K; Sato, T; Shioyama, M; Sunayama, M, 2006)
"A 52-year-old patient with atypical plasmocytoma presented with a bilateral serous detachment of the retina as well as a huge detachment of the pigment epithelium (PE) in the periphery."	1.33	[Bilateral serous detachment of the neurosensory retina and retinal pigment epithelium with rip of the peripheral pigment epithelium]. ( Hager, A; Wiegand, W, 2006)
"Sarcoidosis is a granulomatous disease of unknown etiology and is only rarely seen in infants and children."	1.33	Systemic sarcoidosis after cardiac transplantation in a 9-year-old child. ( Bartram, U; Bauer, J; Schranz, D; Thul, J; Wössmann, W, 2006)
"We report a patient with ulcerative colitis who, in the period following surgery, developed recurrent episodes of acute adrenal insufficiency presenting clinically as a high output ileostomy."	1.32	Acute adrenal insufficiency presenting as high output ileostomy. ( Hemingway, D; Rai, S, 2003)
"The 5% incidence de novo tumors developing among patients treated with azathioprine and prednisolone (n = 241) was similar to the 5."	1.32	De novo tumors after kidney transplantation: the Budapest experience. ( Hídvégi, M; Járay, J; Langer, RM; Perner, F; Tóth, A; Végsö, G, 2003)
"Lithium carbonate was effective for the treatment of depressive disorder without causing side effects such as renal dysfunction."	1.32	Successful lithium carbonate treatment for steroid-induced depression following bone marrow transplantation: a case report. ( Fujisawa, S; Ito, M; Kanamori, H; Onishi, H; Onose, M; Yamada, T, 2003)
" The aim of our study was to review our data to determine if the steroid dosage is associated with the incidence of early complications after bowel resection in patients with prolonged steroid therapy for Crohńs disease (CD)."	1.32	Preoperative steroid administration: effect on morbidity among patients undergoing intestinal bowel resection for Crohńs disease. ( Anthoni, C; Bruewer, M; Kersting, S; Krieglstein, CF; Laukoetter, MG; Rijcken, EJ; Senninger, N; Utech, M, 2003)
" In children with a history of FSGS, caution is necessary when altering the dosing schedule of prednisone."	1.32	Nephrotic syndrome after conversion to alternate day steroids in two children with a history of recurrent FSGS. ( Greenbaum, LA; Hanevold, CD, 2003)
"A 15-year-old boy had temporary hypertropia, supraduction deficit, ipsilateral mydriasis, and accommodative paresis after bilateral endoscopic ethmoidectomy, bilateral partial inferior turbinectomy, septoplasty, and Caldwell-Luc procedures for chronic sinusitis."	1.32	Inferior oblique paresis, mydriasis, and accommodative palsy as temporary complications of sinus surgery. ( Bayramlar, H; Demirel, S; Miman, MC, 2004)
"We describe a patient with type I membranoproliferative glomerulonephritis not associated with hepatitis C."	1.31	Recurrent type I membranoproliferative glomerulonephritis in a renal allograft: successful treatment with plasmapheresis. ( Cosio, FG; Falkenhain, ME; Frankel, WL; Saxena, R; Sedmak, DD, 2000)
"A new technique is described for treating a large cystic degeneration after regression of an intra-abdominal desmoid tumors in patients with familial adenomatous polyposis."	1.31	Transperitoneal drainage for a large cystic degeneration after regression of an intra-abdominal desmoid tumor. ( Goto, Y; Kawasaki, S; Nakada, I; Sato, S; Tabuchi, T; Ubukata, H; Watanabe, Y, 2000)
"The risk of posttransplant cutaneous squamous cell carcinoma in Norwegian heart transplant recipients (n = 148) and kidney transplant recipients (n = 1020) on triple immunosuppressive therapy with cyclosporine, azathioprine, and prednisolone, transplanted between 1983 and 1992, were studied."	1.31	Are heart transplant recipients more likely to develop skin cancer than kidney transplant recipients? ( Fauchald, P; Geiran, O; Gjersvik, P; Hansen, S; Leivestad, T; Møller, B; Pfeffer, P; Simonsen, S, 2000)
"We have treated 20 cases of intractable Meniere's disease with endolymphatic sac drainage & steroid-instillation surgery (EDSS) [Kitahara T, et al."	1.31	[Vestibular symptoms and ENG findings during periods of convalescence after endolymphatic sac drainage and steroid-instillation surgery (EDSS)]. ( Kitahara, T; Kondoh, K; Kubo, T; Mishiro, Y; Murata, J; Okumura, S; Takeda, N, 2000)
"Post-traumatic pyoderma gangrenosum is an ulceronecrotizing dermatosis that is rare and therefore often misinterpreted."	1.31	[Postoperative pyoderma gangrenosum]. ( Born, S; Marsch, WC, 2001)
"Rat models of osteopenia include ovariectomy and long-term glucocorticoid treatment."	1.31	Comparison of osteopenia after gastrectomy, ovariectomy and prednisolone treatment in the young female rat. ( Andersson, N; Håkanson, R; Lehto-Axtelius, D; Surve, VV, 2001)
"A 48-year-old male with treated hypothyroidism underwent mechanical valve replacement for mitral valve regurgitation."	1.31	[A case of pyoderma gangrenosum after mitral valve replacement]. ( Inoue, Y; Kiso, I; Mori, A; Takahashi, R, 2001)
"Multiple brain tumors were found and diagnosed as having B-cell, diffuse large cell type malignant lymphoma."	1.30	[A case of malignant lymphoma after renal transplantation]. ( Ikeda, K; Inoue, S; Matsuura, O; Murakami, S; Oyama, H; Sugiyama, T; Yamao, K, 1997)
"Our data show that symptoms of autoimmune hepatitis, which are responsive to the classical treatment for this condition, can appear in liver-transplant patients while they are on anti-rejection immunosuppression."	1.30	De-novo autoimmune hepatitis after liver transplantation. ( Davies, ET; Donaldson, PT; Hadzić, N; Heaton, ND; Kerkar, N; Mieli-Vergani, G; Portmann, B; Rela, M; Vergani, D, 1998)
"Two eyes that had inferior retinal breaks underwent further surgery to repair the retinal detachment."	1.30	Spontaneous resolution of retinal detachment occurring after macular hole surgery. ( Akduman, L; Del Priore, LV; Kaplan, HJ, 1998)
"Primary biliary cirrhosis (PBC) is an autoimmune disease of the liver frequently associated with extrahepatic autoimmune phenomena."	1.30	Successful steroid treatment of idiopathic thrombocytopenic purpura after orthotopic liver transplantation for primary biliary cirrhosis. ( Fickert, P; Hinterleitner, TA; Sill, H; Stauber, RE; Trauner, M, 1998)
"We report a case of ocular hypotony secondary to a cyclodialysis cleft that developed following a phacoemulsification procedure in which a scleral tunnel incision was used."	1.29	Cyclodialysis cleft following a scleral tunnel incision. ( Maffett, MJ; O'Day, DM, 1994)
"Pyoderma gangrenosum is a rare cutaneous disorder that may complicate recovery after a cardiac operation."	1.29	Pyoderma gangrenosum after coronary artery bypass grafting. ( Olerud, JE; Rand, RP; Verrier, ED, 1993)
"Patients with infections had significantly lower IgG1 levels and CD4 positive lymphocyte numbers but similar total IgG levels compared to patients without infections."	1.29	Predictive value of IgG subclass levels for infectious complications in renal transplant recipients. ( Heidenreich, S; Lang, D; Otte, B; Wieneke, H, 1996)
"We describe two cases of Hodgkin's disease after heart and heart/lung transplants respectively."	1.29	Hodgkin's disease after cardiac transplant: a report of two cases. ( Hood, IM; Mahendra, P; Marcus, RE; McNeil, K, 1996)
" CsA dosage remained unchanged in the range of 200 mg/m2/day; CsA whole blood trough level was 120 to 130 ng/mL throughout the years."	1.28	Long-term results of cyclosporin A therapy in children. ( Bökenkamp, A; Brodehl, J; Hoyer, PF; Offner, G, 1992)
"The intraocular pressure was reduced to about 6 mm Hg in treated eyes from an average pressure of 26 mm Hg."	1.28	[Anti-inflammatory treatment after argon laser trabeculoplasty]. ( Bleckmann, H; Garus, HJ; Huk, B, 1991)
"Patients with non-viral infections seemed to have more depressed lymphocyte responses than non-infected patients."	1.27	Immunological recovery after bone marrow transplantation: role of age, graft-versus-host disease, prednisolone treatment and infections. ( Nilsson, B; Paulin, T; Ringdén, O, 1987)
"Hypothermia is a rare complication of unknown origin in Hodgkin's disease which has been reported after the administration of antineoplastic agents, chlorpromazine and paracetamol."	1.27	Hypothermia in Hodgkin's disease after exploratory laparotomy. ( Appel, HW; Graninger, W; Jung, M; Koppensteiner, R; Lackner, F, 1988)
"Herpes simplex esophagitis is a rare disease occurring mostly in immunocompromised and cancer patients."	1.27	Herpes simplex esophagitis in a renal transplant patient treated with cyclosporine A: a case report. ( Abnrashed, A; Alexander, LC; Check, FE; Fawcett, K; Watts, SJ, 1986)
" A relationship between mortality from a urological complication and steroid dosage was found."	1.26	The urological complications of 1000 renal transplants. ( Bewick, M; Ellis, FG; Mundy, AR; Podesta, ML; Rudge, CJ, 1981)
" This change coincided with the attainment of maintenance steroid dosage (usually prednisolone 10 mg."	1.26	Hyperlipidaemia following renal transplantation. A study of the prevalence, 'natural history' and dietary treatment. ( Gokal, R; Mann, JI; Moore, RA; Morris, PJ, 1979)
" The study revealed no correlation between steroid dosage and postoperative morbidity or mortality."	1.26	Factors which influenced postoperative complications in patients with ulcerative colitis or Crohn's disease of the colon on corticosteroids. ( Allsop, JR; Lee, EC, 1978)
" A significant relation between steroid dosage and blood pressure was found in only a quarter of the hypertensive patients, and in another quarter no cause could be found."	1.26	Hypertension after renal transplantation. ( Alexandre, GP; Bachy, C; van Ypersele de Strihou, C, 1976)

Research

Studies (559)

Authors

Clinical Trials (16)

Trial Overview

Trial Outcomes

Early Development of Scarring in the Grafts

Timeframe	Studies, this research(%)	All Research%
pre-1990	184 (32.92)	18.7374
1990's	118 (21.11)	18.2507
2000's	126 (22.54)	29.6817
2010's	112 (20.04)	24.3611
2020's	19 (3.40)	2.80

Authors	Studies
Valvecchia, G	1
Kaufer, R	1
Ferroni, C	1
Zaldívar, R	1
Masseroni, M	1
Idiart, C	1
Ferroni, V	1
Marino, F	1
Nuñez, M	1
Del Papa, M	1
Passerini, MS	1
Hovanesian, JA	1
Donnenfeld, ED	1
Kazemi, K	1
Hosseinzadeh, A	1
Shahriarirad, R	1
Nikeghbalian, S	1
Kamran, H	1
Hosseinpour, P	1
Tanideh, N	1
Jamshidi, K	1
Lu, AQ	1
Rizk, M	1
O'Rourke, T	1
Goodling, K	1
Lehman, E	1
Scott, IU	2
Pantanelli, SM	1
Karatas Durusoy, G	1
Gümüş, G	1
Öcal, MC	1
Kara, N	1
Raina, UK	1
Ravinesh, K	1
Bhattacharya, S	1
Pavitra, B	1
Thakar, M	1
Mundisugih, J	1
Fernando, H	2
Bergin, P	1
Hare, J	1
Kaye, D	1
Leet, A	1
McGiffin, D	1
Taylor, AJ	1
Hodge, G	1
Hodge, S	1
Liu, H	1
Nguyen, P	1
Holmes-Liew, CL	1
Holmes, M	1
KhalafAllah, MT	1
Basiony, A	1
Salama, A	1
Mouri, H	1
Jo, T	1
Matsui, H	1
Fushimi, K	1
Yasunaga, H	1
Phanish, MK	1
Hull, RP	1
Andrews, PA	1
Popoola, J	1
Kingdon, EJ	1
MacPhee, IAM	1
Lin, CY	1
Liu, WC	1
Chiang, MH	1
Tsai, IT	1
Chen, JY	1
Cheng, WJ	1
Ho, CN	1
Liao, SW	1
Chu, CC	1
Sun, CK	1
Hung, KC	1
Vittitow, JL	1
Williams, JI	1
Hecht, I	1
Taipale, C	1
Tuuminen, R	2
Saini, P	1
Chakraborty, A	1
Singh, A	1
Kumar, S	2
Kansal, NK	1
Kishore, S	1
Asano, R	1
Kitazaki, Y	1
Ikawa, M	1
Kurebayasi, H	1
Koike, H	1
Hamano, T	1
Shorstein, NH	2
Carolan, J	1
Liu, L	2
Alexeeff, SE	1
Amsden, LB	1
Herrinton, LJ	2
Cheng, YH	1
Chang, YF	1
Ko, YC	1
Liu, CJ	1
Leiskau, C	1
Samuel, S	1
Pfister, ED	1
Junge, N	1
Beneke, J	1
Stupak, J	1
Richter, N	1
Vondran, F	1
Schrem, H	1
Baumann, U	1
Kawamoto, N	1
Okita, R	1
Hayashi, M	1
Okada, M	1
Ito, K	1
Ikeda, E	1
Inokawa, H	1
Sarkar, S	1
Bardoloi, N	1
Deb, AK	1
Erichsen, JH	1
Holm, LM	1
Forslund Jacobsen, M	1
Forman, JL	1
Kessel, L	1
Tijunelis, MA	1
Person, E	1
Niziol, LM	1
Musch, DC	1
Ernest, P	1
McBain, M	1
Mian, SI	1
Campochiaro, PA	1
Han, YS	1
Mir, TA	1
Kherani, S	1
Hafiz, G	1
Krispel, C	1
Liu, TYA	1
Wang, J	1
Scott, AW	1
Zimmer-Galler, I	1
Kitamura, N	1
Nakanishi, T	1
Yoshida, Y	1
Higashi, T	1
Tsukada, J	1
Shikino, K	1
Ota, T	1
Uehara, T	1
Ikusaka, M	1
Suzuki, Y	1
Yokoyama, K	1
Terao, M	1
Morioka, T	1
Tsuda, B	1
Niikura, N	1
Okamura, T	1
Yamada, E	1
Imagawa, K	1
Akamatsu, T	1
Tokuda, Y	1
Kumaki, N	1
Hey, P	1
Lokan, J	1
Johnson, P	1
Gow, P	1
Domej, MA	1
Pauzenberger, L	1
Heuberer, PR	1
Anderl, W	1
Kumaria, A	1
Hammett, TC	1
Sitaraman, M	1
D'Aquino, DA	1
Macarthur, DC	1
McCloskey, OM	1
Devine, PA	1
Courtney, AE	1
McCaughan, JA	1
Hamashige, J	1
Umemura, H	1
Asagoe, K	1
Iizuka, T	1
Kikuchi, D	1
Hoteya, S	1
Kaise, M	1
Patel, P	1
Yarur, A	1
Dalal, S	1
Sakuraba, A	1
Rubin, DT	1
Hanauer, SB	1
Hanan, I	1
Raffals, LH	1
Cohen, RD	1
Pekow, J	1
Baartman, BJ	1
Gans, R	1
Goshe, J	2
Greenland, JR	1
Chong, T	1
Wang, AS	1
Martinez, E	1
Shrestha, P	1
Kukreja, J	1
Hays, SR	1
Golden, JA	1
Singer, JP	1
Tang, Q	1
Nazarali, S	1
Cote, SL	1
Gooi, P	1
Hiratsuka, S	1
Takahata, M	1
Hojo, Y	1
Kajino, T	1
Hisada, Y	1
Iwata, A	1
Yamada, K	1
Iwasaki, N	1
Chu, Y	1
Chen, T	1
Li, H	1
Zhou, P	1
Zhang, Y	2
Chen, W	2
Zhong, Y	1
Yao, L	1
Xu, M	1
El Gharbawy, SA	1
Darwish, EA	1
Abu Eleinen, KG	1
Osman, MH	1
Wang, H	1
Zheng, J	1
Zheng, Q	1
Yang, F	1
Ye, C	1
Woo, DM	1
Jhanji, V	2
Danni, R	1
Viljanen, A	1
Aaronson, A	1
Hayashi, K	1
Ohshio, Y	1
Hanaoka, J	1
Hioki, T	1
Kamiya, K	2
Tsuda, H	1
Maekawa, T	1
Komine, M	1
Murata, S	1
Ohtsuki, M	1
Khan, S	1
Pillai, GS	1
Vivek, V	1
Dinesh, K	1
Karim, PM	1
Lane, SS	2
Holland, EJ	2
Özyol, E	1
Özyol, P	1
Joshi, RS	1
Cunha, PA	1
Shinzato, FA	1
Tecchio, GT	1
Weber, SL	1
Brasil, A	1
Avakian, A	1
Duong, HV	1
Westfield, KC	1
Singleton, IC	1
Yates, CJ	1
Fourlanos, S	1
Colman, PG	1
Cohney, SJ	1
Guarisco, JL	1
Yang, CJ	1
Yamada, Y	1
Yoshida, S	1
Suzuki, H	1
Tagawa, T	1
Iwata, T	1
Mizobuchi, T	1
Kawaguchi, N	1
Yoshino, I	1
Long, X	1
Yu, N	1
Zeng, A	1
Long, F	1
Wang, XJ	1
Nagpal, M	1
Lambat, S	1
Mehrotra, N	1
Paranjpe, G	1
Yadav, H	1
Bhardwaj, S	1
Zouvelou, V	1
Vasiliki, Z	1
Velonakis, G	1
Georgios, V	1
Rontogianni, D	1
Dimitra, R	1
Zisis, C	1
Charalambos, Z	1
Asari, S	1
Matsumoto, I	1
Toyama, H	1
Shinzeki, M	1
Goto, T	2
Tanaka, M	2
Shirakawa, S	1
Yamashita, H	1
Ajiki, T	1
Fukumoto, T	1
Ku, Y	1
Zhou, Y	1
Song, R	1
Li, Y	1
Ohkubo, H	1
Kunii, E	1
Moriyama, S	1
Niimi, A	1
Fayad, T	1
William, E	1
Tawfik, N	1
Habashy, B	1
Abou-Youssef, HS	1
Shokry, S	1
Khalil, S	1
Morsy, A	1
Barsoum, R	1
Nishiwaki, H	1
Hasegawa, T	1
Nagayama, Y	1
Kaneshima, N	1
Takayasu, M	1
Hirose, M	1
Komukai, D	1
Inoue, Y	3
Koiwa, F	1
Yoshimura, A	1
von Düring, ME	1
Jenssen, T	3
Bollerslev, J	1
Åsberg, A	2
Godang, K	1
Eide, IA	1
Dahle, DO	1
Hartmann, A	4
Champagne, S	1
Anctil, JL	1
Goyette, A	1
Lajoie, C	1
Des Marchais, B	1
Thakkar, B	1
Patel, N	1
Bohora, S	1
Bhalodiya, D	1
Singh, T	1
Madan, T	1
Shah, S	1
Poptani, V	1
Shukla, A	1
Nijhoff, MF	1
Engelse, MA	1
Dubbeld, J	1
Braat, AE	1
Ringers, J	1
Roelen, DL	1
van Erkel, AR	1
Spijker, HS	1
Bouwsma, H	1
van der Boog, PJ	1
de Fijter, JW	1
Rabelink, TJ	1
de Koning, EJ	1
Krishnamoorthy, TL	1
Miezynska-Kurtycz, J	1
Hodson, J	1
Gunson, BK	1
Neuberger, J	1
Milkiewicz, P	1
Oo, YH	1
Waxman, MD	1
Nitta, D	1
Kinugawa, K	1
Imamura, T	1
Hatano, M	1
Ono, M	1
Nakamura, F	1
Kurokawa, M	2
Komuro, I	1
Tyraskis, A	1
Davenport, M	1
Murphy, B	1
Walsh, M	1
McKenna, K	1
Hoerster, R	1
Stanzel, TP	1
Bachmann, BO	1
Siebelmann, S	1
Felsch, M	1
Cursiefen, C	1
Mimura, M	1
Ueki, M	1
Oku, H	1
Sato, B	1
Ikeda, T	2
Shifa, J	1
Abebe, W	1
Bekele, N	1
Habte, D	1
Tyagi, M	1
Ambiya, V	1
Rani, PK	1
Ibikunle, AA	1
Adeyemo, WL	1
Ladeinde, AL	1
AlKheraiji, NF	1
AlKheraiji, AF	1
Stone, DU	1
Wilson, ME	1
Lambert, SR	1
Plager, DA	1
VanderVeen, D	1
Roarty, J	1
O'Halloran, H	1
Kaur, S	1
Sukhija, J	1
Taylan, C	1
Goebel, H	2
Beck, BB	1
Dötsch, J	1
Nuesken, KD	1
Hoppe, B	1
Weber, LT	1
Liebau, MC	1
Leal, R	1
Pinto, H	1
Alves, R	1
Figueiredo, A	1
Roh, JL	1
Park, CI	1
Kim, A	1
Stark, WJ	1
Shibatani, M	1
Fujioka, M	3
Arai, Y	2
Takahashi, K	2
Ueshima, K	1
Okamoto, M	4
Yoshimura, N	5
Hirota, Y	2
Fukushima, W	2
Kubo, T	4
Patel, NN	1
Teng, CC	1
Sperber, LT	1
Dodick, JM	1
Precupanu, CM	1
Girodet, J	1
Mariani, P	1
Zanni, M	1
Mathiot, C	1
Escande, MC	1
Brault, P	1
Decaudin, D	1
Hélaine, L	1
Cadic, A	1
Magro, E	1
Simon, A	1
Kiss, G	1
Gueret, G	1
Arvieux, CC	1
Paganelli, F	2
Cardillo, JA	2
Melo, LA	2
Lucena, DR	1
Silva, AA	1
Oliveira, AG	2
Höfling-Lima, AL	1
Nguyen, QD	1
Kuppermann, BD	1
Belfort, R	1
Rikitake, K	1
Sato, M	1
Ohtsubo, S	1
Itoh, T	1
Ozbek, Z	1
Arikan, G	1
Yaman, A	1
Oner, H	1
Bajin, MS	1
Saatci, AO	1
Cheng, FW	1

Trial	Phase	Enrollment	Study Type	Start Date	Status
The D3 Study: Drug Delivery vs Drops - A Prospective Clinical Study Evaluating Dexycu vs Prednisolone Acetate 1% in Controlling Post-operative Pain and Inflammation in Patients Undergoing Sequential Cataract Surgery[NCT04273282]	Phase 4	31 participants (Actual)	Interventional	2019-12-16	Completed
Effect of Drop-less Surgery Compared to Topical NSAID Alone and Combination of Steroid and NSAID on Central Macular Thickness After Cataract Surgery, a Randomized Controlled Trial[NCT03383328]	Phase 4	470 participants (Actual)	Interventional	2018-02-01	Completed
Outcome of Cataract Surgery in Patient With Uveitis[NCT04333069]		50 participants (Anticipated)	Interventional	2020-04-10	Not yet recruiting
Evaluating the Efficacy, Compliance, and Patient Satisfaction of a New Dropless Postoperative Regimen After Cataract Surgery in a Vulnerable, County-hospital Population[NCT05157113]	Phase 4	70 participants (Anticipated)	Interventional	2022-05-31	Recruiting
A Randomized, Masked Comparison of Topical Ketorolac 0,4% Versus Placebo in Cataract Surgery.[NCT01542190]	Phase 4	80 participants (Anticipated)	Interventional	2011-02-28	Completed
Phase I/II Comparative Study of a Single Intraoperative Sub-Tenon's Capsule Injection of Triamcinolone and Ciprofloxacin in a Controlled-Release System Versus 1% Prednisolone and 0.3% Ciprofloxacin Eyedrops for Cataract Surgery[NCT00431028]	Phase 1/Phase 2	140 participants (Actual)	Interventional	2005-09-30	Terminated (stopped due to Terminated)
Comparison of Two Different Acrylate Intraocular Lenses in Cataract Surgery in Patients With Non-infectious Uveitis[NCT00403832]		60 participants	Interventional	2005-08-31	Completed
Three-dimensional Facial Swelling Evaluation of Pre-operative Single-dose of Prednisone in Third Molar Surgery: a Split-mouth Randomized Controlled Trial[NCT05830747]	Phase 4	34 participants (Actual)	Interventional	2022-02-01	Completed
Post-operative Course of Dexamethasone to Reduce Tonsillectomy Morbidity[NCT04879823]	Phase 3	300 participants (Anticipated)	Interventional	2021-08-05	Recruiting
A Randomised Controlled Comparison of Campath-Tacrolimus vs IL2R MoAb-Tacrolimus/Mycophenolate Mofetil in Kidney Transplantation[NCT00246129]	Phase 4	123 participants (Actual)	Interventional	2005-10-31	Completed
A Comparison of a Single Orbital Floor Injection of Triamcinolone Versus Conventional Steroid and Antibiotic Drops Used Post Operatively in Uneventful Phacoemulsification Surgery[NCT00789971]		150 participants (Actual)	Interventional	2007-03-31	Completed
The Use of Campath-1H, Tacrolimus, and Sirolimus Followed by Sirolimus Withdrawal in Renal Transplant Patients[NCT00078559]	Phase 1/Phase 2	10 participants (Actual)	Interventional	2003-11-30	Completed
Immunosuppression Minimization to Single Drug Therapy With Sirolimus (Rapamune) in Pediatric Transplantation[NCT00768729]	Phase 1	7 participants (Actual)	Interventional	2009-05-31	Completed
A Phase II Exploratory Study to Determine the Safety and Study the Immunomodulatory Functions of Induction Therapy With Campath, Combined With Chronic Immunosuppression With Mycophenolate Mofetil and Sirolimus[NCT00240994]	Phase 2	35 participants (Actual)	Interventional	2005-01-31	Completed
Dropless Pars Plana Vitrectomy Study[NCT05331664]	Phase 4	168 participants (Anticipated)	Interventional	2022-07-25	Recruiting
The Use of Novel Therapies to Reconstitute Blood Cell Production and Promote Organ Performance Using Bone Marrow Failure as a Model: a Pilot, Phase I/II Study of the Amino Acid Leucine in the Treatment of Patients With Transfusion-Dependent Diamond Blackf[NCT01362595]	Phase 1/Phase 2	55 participants (Actual)	Interventional	2013-06-30	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Biopsy proven Calcineurin Inhibitor (CNI) toxicity free survival (NCT00246129)
Timeframe: 1 year

Graft Function: Level of Creatinine

Graft Survival Censored for Death With Function

Intervention	Percentage of participants with no scar (Number)
Campath-Tacrolimus	96
Daclizumab-Tacrolimus-Mycophenolate	90

Intervention	mmol/L (Mean)
Campath-Tacrolimus	127.3
Daclizumab-Tacrolimus-Mycophenolate	147.0

Graft survival (defined as grafts maintaining dialysis independence) (NCT00246129)
Timeframe: 2 years

Initial Length of Stay in Hospital

Occurrence of Rejection Episodes

Intervention	Percentage of grafts (Number)
Campath-Tacrolimus	91
Daclizumab-Tacrolimus-Mycophenolate	95

Intervention	Days (Mean)
Campath-Tacrolimus	11.7
Daclizumab-Tacrolimus-Mycophenolate	12.1

Biopsy-proven rejection episodes classified using Banff criteria (NCT00246129)
Timeframe: 1 year

Occurrence of Significant Episodes of Infection

Intervention	Percentage of patients (Number)
Campath Tacrolimus	91.2
Daclizumab-Tacrolimus-Mycophenolate	82.3

Occurence of infection of sufficient severity to produce positive cultures or Nucleic-acid test results from blood, urine, or other body fluids (NCT00246129)
Timeframe: 1 year

One Year Survival With a Functioning Graft

Intervention	# of occurrences per 100 patient years (Number)
Campath-Tacrolimus	73
Daclizumab-Tacrolimus-Mycophenolate	76

"One year survival with a functioning graft, defined as transplant recipient remaining alive and dialysis-independent. the functioning graft is a graft still functioning at the time of analysis.~Graft function was estimated using the Modification of Diet in Renal Disease four-variable formula and comparison of graft function between arms undertaken with Student'st test." (NCT00246129)
Timeframe: 1 year

Patient Survival Censored for Death With Function

Change in Renal Function as Measured by Serum Creatinine, Stratified by Withdrawal Status

Intervention	Percent of patients (Number)
Campath-Tacrolimus	97.6
Daclizumab-Tacrolimus-Mycophenolate	95.1

Intervention	Percentage of transplant recipients (Number)
Campath-Tacrolimus	98
Daclizumab-Tacrolimus-Mycophenolate	98

Mean change from transplantation to Month 48 in serum creatinine. Normal serum creatinine range is from 0.7 - 1.4 mg/dL. In a transplant population, starting serum creatinine is higher than normal range. A negative change indicates better renal function (NCT00078559)
Timeframe: Transplantation to end of study (up to four years post-transplant)

Number of Acute Rejections Between Initiation of Sirolimus Withdrawal and End of Study

Intervention	mg/dL (Mean)
Alemtuzumab (Withdrawn From Sirolimus)	-4.2
Alemtuzumab (Not Withdrawn From Sirolimus)	-5.4

"Acute rejections[1] between initiation of sirolimus withdrawal and end of study~1] Acute rejection is defined as a biopsy-proven rejection: a renal biopsy demonstrates acute cellular or humoral rejection of Banff[2] Grade 1B or greater; or presumed rejection in the absence of biopsy-proven rejection, the participant is treated for an unexplained 20% increase in serum creatinine.~[2] Reference: Racusen LC, Solez K, Colvin RB et al,The Banff 97 working classification of renal allograft pathology. Kidney Int,55: 713-723, 1999" (NCT00078559)
Timeframe: Initiation of sirolimus to end of study (up to four years post-transplant)

Number of Acute Rejections in All Enrolled Participants

Intervention	Rejection Events (Number)
Alemtuzumab	0

"Number of acute rejections[1] in all enrolled subjects from the time of transplantation to the end of the trial (four years post-transplant)~Acute rejection is defined as a biopsy-proven rejection: a renal biopsy demonstrates acute cellular or humoral rejection of Banff[2] Grade 1B or greater; or presumed rejection in the absence of biopsy-proven rejection, the participant is treated for an unexplained 20% increase in serum creatinine.~Reference: Racusen LC, Solez K, Colvin RB et al,The Banff 97 working classification of renal allograft pathology. Kidney Int,55: 713-723, 1999" (NCT00078559)
Timeframe: Four years post-transplant

Number of Acute Rejections in All Enrolled Participants Following Sirolimus Withdrawal

Intervention	Rejection Events (Number)
Alemtuzumab	1

"Following sirolimus withdrawal, the number of acute rejections[1] in all enrolled participants~1] Acute rejection is defined as a biopsy-proven rejection: a renal biopsy demonstrates acute cellular or humoral rejection of Banff[2] Grade 1B or greater; or presumed rejection in the absence of biopsy-proven rejection, the participant is treated for an unexplained 20% increase in serum creatinine.~[2] Reference: Racusen LC, Solez K, Colvin RB et al,The Banff 97 working classification of renal allograft pathology. Kidney Int,55: 713-723, 1999" (NCT00078559)
Timeframe: Transplantation to end of study (up to four years post-transplant)

Number of Alemtuzumab Associated Adverse Events, Stratified by Sirolimus Withdrawal Status

Intervention	Rejection Events (Number)
Alemtuzumab	0

(NCT00078559)
Timeframe: Transplantation to end of study (up to four years post-transplant)

Number of Deaths Stratified by Sirolimus Withdrawal Status

Intervention	adverse events (Number)
Alemtuzumab (Withdrawn From Sirolimus)	2
Alemtuzumab (Not Withdrawn From Sirolimus)	8

Participants who died during the study, all cause(s) (NCT00078559)
Timeframe: Transplantation to Death (up to four years post-transplant)

Number of Participants Requiring Anti-lymphocyte Therapy for an Acute Rejection, Stratified by Sirolimus Withdrawal Status

Intervention	deaths (Number)
Alemtuzumab (Withdrawn From Sirolimus)	0
Alemtuzumab (Not Withdrawn From Sirolimus)	0

"Participants who experienced acute rejection[1] during study which required anti-lymphocyte (OKT3, ATG) therapy~1] Acute rejection is defined as a biopsy-prove rejection: a renal biopsy demonstrates acute cellular or humoral rejection of Banff[2] Grade 1B or greater; or presumed rejection in the absence of biopsy-proven rejection, the participant is treated for an unexplained 20% increase in serum creatinine.~[2] Reference: Racusen LC, Solez K, Colvin RB et al,The Banff 97 working classification of renal allograft pathology. Kidney Int,55: 713-723, 1999" (NCT00078559)
Timeframe: Transplantation to acute rejection (up to four years post-transplantation)

Number of Participants Who Experienced Graft Loss Stratified by Sirolimus Withdrawal Status

Intervention	participants (Number)
Alemtuzumab (Withdrawn From Sirolimus)	0
Alemtuzumab (Not Withdrawn From Sirolimus)	0

"Participants who experienced graft loss[1] during study~[1]Graft loss is defined as the institution of chronic dialysis (at least 6 consecutive weeks, excluding participants with delayed graft function), transplant nephrectomy, or retransplantation" (NCT00078559)
Timeframe: Transplantation to Graft Loss (up to four years post-transplantation)

Number of Severe Acute Rejections Stratified by Sirolimus Withdrawal Status

Intervention	participants (Number)
Alemtuzumab (Withdrawn From Sirolimus)	0
Alemtuzumab (Not Withdrawn From Sirolimus)	0

"Participants who experienced severe acute rejections[1] during study~Severe acute rejection is defined as that which requires treatment with anti-lymphocyte antibody or is histologically evaluated as Type IIA or greater using the Banff 1997 criteria[2]~Reference: Racusen LC, Solez K, Colvin RB et al,The Banff 97 working classification of renal allograft pathology. Kidney Int,55: 713-723, 1999" (NCT00078559)
Timeframe: Transplantation to severe acute rejection (up to four years post-transplantation)

Number of Side Effects of Conventional Immunosuppression, Stratified by Withdrawal Status

Intervention	Rejection Events (Number)
Alemtuzumab (Withdrawn From Sirolimus)	0
Alemtuzumab (Not Withdrawn From Sirolimus)	0

Side effects of conventional immunosuppression include increased body weight and hypertension (NCT00078559)
Timeframe: Transplantation to end of study (up to four years post-transplant)

Number of Sirolimus Associated Adverse Events, Stratified by Sirolimus Withdrawal Status

Intervention	side effects (Number)
Alemtuzumab (Withdrawn From Sirolimus)	2
Alemtuzumab (Not Withdrawn From Sirolimus)	6

(NCT00078559)
Timeframe: Transplantation to end of study (up to four years post-transplant)

Number of Tacrolimus Associated Adverse Events, Stratified by Sirolimus Withdrawal Status

Intervention	adverse events (Number)
Alemtuzumab (Withdrawn From Sirolimus)	2
Alemtuzumab (Not Withdrawn From Sirolimus)	7

(NCT00078559)
Timeframe: Transplantation to end of study (up to four years post-transplant)

Time From Transplantation to Acute Rejection in Participants for Whom Acute Rejection Occurred During the 1 Year Post-transplant Period

Intervention	adverse events (Number)
Alemtuzumab (Withdrawn From Sirolimus)	0
Alemtuzumab (Not Withdrawn From Sirolimus)	2

"Time (days) to acute rejection[1] for participants occurring during the year following transplantation~1] Acute rejection is defined as a biopsy-proven rejection: a renal biopsy demonstrates acute cellular or humoral rejection of Banff[2] Grade 1B or greater; or presumed rejection in the absence of biopsy-proven rejection, the participant is treated for an unexplained 20% increase in serum creatinine.~[2] Reference: Racusen LC, Solez K, Colvin RB et al,The Banff 97 working classification of renal allograft pathology. Kidney Int,55: 713-723, 1999" (NCT00078559)
Timeframe: Transplantation to acute rejection (up to one year post-transplant)

Time From Transplantation to Acute Rejection in Participants for Whom Sirolimus Withdrawal Was Not Initiated

Intervention	Days (Number)
Alemtuzumab	274

"Time (days) to acute rejection[1] for participants where sirolimus was not initiated~1] Acute rejection is defined as a biopsy-proven rejection: a renal biopsy demonstrates acute cellular or humoral rejection of Banff[2] Grade 1B or greater; or presumed rejection in the absence of biopsy-proven rejection, the participant is treated for an unexplained 20% increase in serum creatinine.~[2] Reference: Racusen LC, Solez K, Colvin RB et al,The Banff 97 working classification of renal allograft pathology. Kidney Int,55: 713-723, 1999" (NCT00078559)
Timeframe: Transplantation to acute rejection (up to four years post-transplantation)

The Proportion of Participants With Graft Loss or Death Within 12 Months Post Kidney Transplantation

Intervention	Days (Number)
Alemtuzumab	274

Graft loss is defined as the need for dialysis for more than 30 days duration, allograft nephrectomy, or the decision to withdraw immunosuppression due to graft failure. (NCT00240994)
Timeframe: Up to one year post kidney transplantation procedure

Response to Leucine in Transfusion Dependent Patients With Diamond Blackfan Anemia

Intervention	Proportion of participants (Number)
Alemtuzumab (Campath)	0.057

"The primary outcome is the type of response observed at 9 months. Response to treatment can be one of the following:~Complete response (CR): Hb > 9 gm/dL and transfusion-independence as defined in DBA~Partial response (PR): Hb < 9 gm/dL and increased reticulocyte count to greater than baseline.~No response (NR): no change in transfusion requirements and no significant change reticulocyte count from baseline~Progression: worsening of disease as defined by the need for more frequent transfusions" (NCT01362595)
Timeframe: 9 Months

Article	Year
Difluprednate versus Prednisolone Acetate after Cataract Surgery: a Systematic Review and Meta-Analysis. BMJ open, 2019, 11-02, Volume: 9, Issue:11 Topics: Animals; Anti-Inflammatory Agents; Cataract Extraction; Fluprednisolone; Humans; Postoperative Care;	2019
[A case of post-surgical inflammatory neuropathy with lower-extremity weakness after surgery for anorectal malignant melanoma that showed the effectiveness of immunotherapy]. Rinsho shinkeigaku = Clinical neurology, 2020, Nov-27, Volume: 60, Issue:11 Topics: Administration, Oral; Anus Neoplasms; Humans; Inflammation; Male; Melanoma; Middle Aged; Peripheral	2020
Acute graft-versus-host disease following simultaneous pancreas-kidney transplantation: report of a case. Surgery today, 2015, Volume: 45, Issue:12 Topics: Acute Disease; Adolescent; Adult; Diabetes Mellitus, Type 1; Fatal Outcome; Female; Graft vs Host Di	2015
Steroids after the Kasai procedure for biliary atresia: the effect of age at Kasai portoenterostomy. Pediatric surgery international, 2016, Volume: 32, Issue:3 Topics: Age Factors; Biliary Atresia; Cholangitis; Glucocorticoids; Humans; Infant; Infant, Newborn; Liver;	2016
Emergent medical and surgical management of mediastinal infantile hemangioma with symptomatic spinal cord compression: case report and literature review. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2010, Volume: 26, Issue:12 Topics: Adrenergic beta-Antagonists; Anti-Inflammatory Agents; Anticoagulants; Child, Preschool; Decompressi	2010
Hepatocellular carcinoma in cirrhotic liver with graft-versus-host disease. Annals of hematology, 2012, Volume: 91, Issue:9 Topics: Carcinoma, Hepatocellular; Catheter Ablation; Chronic Disease; Combined Modality Therapy; Cyclospori	2012
Diffuse large B-cell lymphoma arising primarily at the stoma after bladder reconstruction using ileal conduit. Internal medicine (Tokyo, Japan), 2012, Volume: 51, Issue:6 Topics: Aged; Antigens, CD20; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carcinoma,	2012
Diarrhea in chronic inflammatory bowel diseases. Gastroenterology clinics of North America, 2012, Volume: 41, Issue:3 Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antidiarrheals; Bacterial Infections	2012
[Diffuse lymphoproliferative disease after renal transplantation and its relation with Epstein-Barr virus. Experience at one center]. Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2002, Volume: 22, Issue:5 Topics: Adolescent; Adult; Aged; Comorbidity; Cytomegalovirus Infections; Epstein-Barr Virus Infections; Fem	2002
Aspergillus endocarditis in a native valve after amphotericin B treatment. The Annals of thoracic surgery, 2004, Volume: 78, Issue:4 Topics: Amphotericin B; Anti-Infective Agents; Aspergillosis; Aspergillus fumigatus; Candidiasis; Drug Resis	2004
Sirolimus may not cause neurotoxicity in kidney and liver transplant recipients. Neurology, 2004, Nov-23, Volume: 63, Issue:10 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Calcineurin; Child; Drug Therapy, Combination; Female; H	2004
New-onset posttransplantation diabetes mellitus: insulin resistance or insulinopenia? Impact of immunosuppressive drugs, cytomegalovirus and hepatitis C virus infection. Current diabetes reviews, 2005, Volume: 1, Issue:1 Topics: Antihypertensive Agents; Cytomegalovirus Infections; Diabetes Mellitus; Hepatitis C; Humans; Immunos	2005
Malignant tumours after renal transplantation. Scandinavian journal of urology and nephrology, 1996, Volume: 30, Issue:5 Topics: Azathioprine; Cyclosporine; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Kidney Tran	1996
[Performance and postoperative care of heart transplantation]. Deutsche medizinische Wochenschrift (1946), 1997, Nov-14, Volume: 122, Issue:46 Topics: Anti-Inflammatory Agents; Azathioprine; Biopsy; Cyclosporine; Drug Therapy, Combination; Follow-Up S	1997
[Myelodysplastic syndrome (RAEB in T) developed in a renal allograft recipient]. [Rinsho ketsueki] The Japanese journal of clinical hematology, 1998, Volume: 39, Issue:8 Topics: Anemia, Refractory, with Excess of Blasts; Azathioprine; Humans; Immunosuppressive Agents; Kidney Ne	1998
[Subacute motor neuronopathy associated with myasthenia gravis and thymoma]. Rinsho shinkeigaku = Clinical neurology, 1999, Volume: 39, Issue:7 Topics: Autoantibodies; Autoimmunity; Female; Humans; Middle Aged; Motor Neuron Disease; Myasthenia Gravis;	1999
Basedow's disease and chronic ulcerative colitis: a case report and review of the Japanese literature. Internal medicine (Tokyo, Japan), 2001, Volume: 40, Issue:1 Topics: Adult; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antithyroid Agent	2001
[Pathology of the gastrointestinal tract after kidney transplantation]. Terapevticheskii arkhiv, 1978, Volume: 50, Issue:6 Topics: Acute Disease; Duodenal Ulcer; Gastric Juice; Humans; Intestinal Diseases; Kidney Transplantation; P	1978
Diagnosis and treatment of chronic postoperative bacterial endophthalmitis. Ophthalmic surgery, 1988, Volume: 19, Issue:8 Topics: Bacterial Infections; Cataract Extraction; Cephalosporins; Chronic Disease; Endophthalmitis; Female;	1988
A review of 23 human lung transplantations by 20 surgeons. The Annals of thoracic surgery, 1970, Volume: 9, Issue:6 Topics: Adolescent; Adult; Antilymphocyte Serum; Azathioprine; Dactinomycin; Female; Histocompatibility Test	1970
Sclerosing cholangitis. Clinics in gastroenterology, 1973, Volume: 2, Issue:1 Topics: Age Factors; Anti-Bacterial Agents; Antifungal Agents; Bacterial Infections; Bile Duct Neoplasms; Bl	1973

Article	Year
Difluprednate 0.05% twice a day vs prednisolone acetate 1% 4 times a day for cataract postsurgical inflammation treatment: noninferiority trial. Journal of cataract and refractive surgery, 2022, 07-01, Volume: 48, Issue:7 Topics: Cataract; Eye Diseases; Fluprednisolone; Humans; Inflammation; Phacoemulsification; Postoperative Co	2022
Intracameral dexamethasone 9% vs prednisolone acetate 1% in controlling postoperative pain and inflammation in patients undergoing cataract surgery. Journal of cataract and refractive surgery, 2022, 08-01, Volume: 48, Issue:8 Topics: Cataract; Cataract Extraction; Dexamethasone; Humans; Inflammation; Moxifloxacin; Ophthalmic Solutio	2022
Comparison of topical steroids versus adjunctive intracameral triamcinolone versus posterior subtenon triamcinolone in pediatric cataract surgery. Indian journal of ophthalmology, 2023, Volume: 71, Issue:1 Topics: Cataract; Child; Child, Preschool; Eye Diseases; Glucocorticoids; Humans; Inflammation; Intraocular	2023
Loteprednol etabonate gel 0.5% vs prednisolone acetate suspension 1% for the treatment of inflammation after cataract surgery in children. Journal of cataract and refractive surgery, 2020, Volume: 46, Issue:8 Topics: Androstadienes; Cataract; Child; Double-Blind Method; Humans; Inflammation; Intraocular Pressure; Lo	2020
Comparison between 0.1% Nepafenac and 1% Prednisolone Eye Drop in Postoperative Management Following Micro-incisional Cataract Surgery. Korean journal of ophthalmology : KJO, 2021, Volume: 35, Issue:3 Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzeneacetamides; Cataract; Double-Blind Method; Humans; O	2021
Prednisolone and Ketorolac vs Ketorolac Monotherapy or Sub-Tenon Prophylaxis for Macular Thickening in Cataract Surgery: A Randomized Clinical Trial. JAMA ophthalmology, 2021, Oct-01, Volume: 139, Issue:10 Topics: Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cataract; Cataract Extracti	2021
Increased Frequency of Topical Steroids Provides Benefit in Patients With Recalcitrant Postsurgical Macular Edema. American journal of ophthalmology, 2017, Volume: 178 Topics: Administration, Topical; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cataract Extraction; Dose-Re	2017
Efficacy of addition of nepafenac 0.1% to steroid eye drops in prevention of post-phaco macular edema in high-risk eyes. European journal of ophthalmology, 2019, Volume: 29, Issue:4 Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Benzeneacetamides; Cataract; Drug Combinations	2019
Preoperative anti-inflammatory treatment of diabetic patients does not improve recovery from cataract surgery when postoperatively treated with a combination of prednisolone acetate and nepafenac. Acta ophthalmologica, 2019, Volume: 97, Issue:6 Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents; Benzeneacetamides; Cataract Extraction; Diabetes	2019
Efficacy and tolerability of a gatifloxacin/prednisolone acetate fixed combination for topical prophylaxis and control of inflammation in phacoemulsification: a 20-day-double-blind comparison to its individual components. Clinics (Sao Paulo, Brazil), 2013, Volume: 68, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Inflammatory Agents; Double-Blind Method	2013
Treatment paradigm after uncomplicated cataract surgery: a prospective evaluation. Acta ophthalmologica, 2015, Volume: 93, Issue:4 Topics: Administration, Topical; Anti-Inflammatory Agents, Non-Steroidal; Azepines; Benzophenones; Bromobenz	2015
Screening for new-onset diabetes after kidney transplantation: limitations of fasting glucose and advantages of afternoon glucose and glycated hemoglobin. Transplantation, 2013, Oct-27, Volume: 96, Issue:8 Topics: Adult; Blood Glucose; Circadian Rhythm; Cross-Sectional Studies; Fasting; Female; Glucocorticoids; G	2013
Topical nepafenac 0.1% alone versus prednisolone acetate 1% as postoperative anti-inflammatory agents in small gauge vitrectomy. Indian journal of ophthalmology, 2014, Volume: 62, Issue:5 Topics: Anti-Inflammatory Agents; Benzeneacetamides; Dose-Response Relationship, Drug; Double-Blind Method;	2014
Eight-year outcomes of 'the Cairo Kidney Centre sequential protocol'. Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation, 2015, Volume: 13 Suppl 1 Topics: Adult; Calcineurin Inhibitors; Cyclosporine; Drug Administration Schedule; Drug Substitution; Drug T	2015
Influence on intraocular pressure of anti-inflammatory treatments after selective laser trabeculoplasty. Journal francais d'ophtalmologie, 2015, Volume: 38, Issue:7 Topics: Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Combined Modalit	2015
Oral health-related quality of life following third molar surgery with either oral administration or submucosal injection of prednisolone. Oral and maxillofacial surgery, 2016, Volume: 20, Issue:4 Topics: Administration, Oral; Adult; Female; Humans; Male; Molar, Third; Mouth Mucosa; Oral Health; Postoper	2016
A prospective, randomized trial for use of prednisolone in patients with facial nerve paralysis after parotidectomy. American journal of surgery, 2008, Volume: 196, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Chi-Square Distribution; Double-Blind Method; Facial Nerve; Facial P	2008
A single intraoperative sub-tenon's capsule injection of triamcinolone and ciprofloxacin in a controlled-release system for cataract surgery. Investigative ophthalmology & visual science, 2009, Volume: 50, Issue:7 Topics: Aged; Anterior Chamber; Anti-Infective Agents; Anti-Inflammatory Agents; Ciprofloxacin; Connective T	2009
Comparison of orbital floor triamcinolone acetonide and oral prednisolone for cataract surgery management in patients with non-infectious uveitis. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2010, Volume: 248, Issue:5 Topics: Administration, Oral; Anterior Chamber; Cataract; Female; Fluorescein Angiography; Glucocorticoids;	2010
The effect of prednisolone on reduction of complaints after impacted third molar removal. Stomatologija, 2010, Volume: 12, Issue:1 Topics: Adolescent; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase	2010
Impact of defunctioning loop ileostomy on outcome after restorative proctocolectomy for ulcerative colitis. International journal of colorectal disease, 2011, Volume: 26, Issue:5 Topics: Adolescent; Adult; Aged; Colitis, Ulcerative; Female; Humans; Ileostomy; Male; Middle Aged; Postoper	2011
The effect of a postoperative course of oral prednisone on postoperative morbidity following childhood tonsillectomy. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2012, Volume: 147, Issue:3 Topics: Administration, Oral; Adolescent; Anti-Inflammatory Agents; Child; Child, Preschool; Double-Blind Me	2012
Effect of preoperative use of topical prednisolone acetate, ketorolac tromethamine, nepafenac and placebo, on the maintenance of intraoperative mydriasis during cataract surgery: a randomized trial. Indian journal of ophthalmology, 2012, Volume: 60, Issue:4 Topics: Administration, Topical; Aged; Anti-Inflammatory Agents; Benzeneacetamides; Cataract Extraction; Cyc	2012
Loteprednol etabonate 0.5% versus prednisolone acetate 1.0% for the treatment of inflammation after cataract surgery. Journal of cataract and refractive surgery, 2013, Volume: 39, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Androstadienes; Anterior Chamber; Anti-Allergic Agents; Anti-Inflamm	2013
First results from a prospective randomized trial comparing steroid-free induction therapy with tacrolimus and MMF versus tacrolimus and steroids in patients after liver transplantation for HCV. Transplantation proceedings, 2002, Volume: 34, Issue:5 Topics: Adrenal Cortex Hormones; Adult; Aged; Drug Therapy, Combination; Female; Follow-Up Studies; Hepatiti	2002
Early steroid withdrawal in renal transplantation with tacrolimus dual therapy: a pilot study. Transplantation, 2002, Dec-27, Volume: 74, Issue:12 Topics: Acute Disease; Adult; Aged; Anti-Inflammatory Agents; Creatinine; Diabetes Mellitus; Drug Therapy, C	2002
Comparison of topical prednisolone acetate, ketorolac tromethamine and fluorometholone acetate in reducing inflammation after phacoemulsification. Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2003, Volume: 86, Issue:2 Topics: Administration, Topical; Adult; Aged; Analysis of Variance; Anti-Inflammatory Agents; Chi-Square Dis	2003
Reduction of immunosuppressant therapy requirement in heart transplantation by calcitriol. Transplantation, 2003, Jun-27, Volume: 75, Issue:12 Topics: Bone Density; Calcitriol; Calcium; Creatinine; Cyclosporine; Dose-Response Relationship, Drug; Heart	2003
Efficacy and safety of rimexolone 1% versus prednisolone acetate 1% in the control of postoperative inflammation following phacoemulsification cataract surgery. International ophthalmology, 2004, Volume: 25, Issue:1 Topics: Double-Blind Method; Female; Glucocorticoids; Humans; Inflammation; Lens Implantation, Intraocular;	2004
Steroid prophylaxis in eyes with uveitis undergoing phacoemulsification. The British journal of ophthalmology, 2004, Volume: 88, Issue:9 Topics: Administration, Oral; Anti-Inflammatory Agents; Blood-Aqueous Barrier; Female; Glucocorticoids; Huma	2004
Steroid sparing with tacrolimus and mycophenolate mofetil in renal transplantation. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2004, Volume: 4, Issue:11 Topics: Creatinine; Dose-Response Relationship, Drug; Drug Administration Schedule; Ethnicity; Female; Glome	2004
A single intraoperative sub-Tenon's capsule triamcinolone acetonide injection for the treatment of post-cataract surgery inflammation. Ophthalmology, 2004, Volume: 111, Issue:11 Topics: Aged; Aged, 80 and over; Connective Tissue; Double-Blind Method; Female; Glucocorticoids; Humans; In	2004
Insulin resistance after renal transplantation: the effect of steroid dose reduction and withdrawal. Journal of the American Society of Nephrology : JASN, 2004, Volume: 15, Issue:12 Topics: Body Weight; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Glucocorticoids; Graft Rejection; H	2004
Rejection rates in a randomised trial of tacrolimus monotherapy versus triple therapy in liver transplant recipients with hepatitis C virus cirrhosis. Transplant infectious disease : an official journal of the Transplantation Society, 2006, Volume: 8, Issue:1 Topics: Adult; Aged; Azathioprine; Drug Therapy, Combination; Female; Graft Rejection; Hepatitis C; Humans;	2006
Effect of topical prednisolone and diclofenac on the short-term change in morphology of posterior capsular opacification. American journal of ophthalmology, 2006, Volume: 142, Issue:4 Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Ca	2006
Injection therapy of lumbar facet syndrome: a prospective study. Acta neurochirurgica, 2006, Volume: 148, Issue:11 Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anti-Inflammatory Agents; Drug Combinations; Fem	2006
Anti-inflammatory efficacy of a single posterior subtenon injection of triamcinolone acetonide versus prednisolone acetate 1% eyedrops after pars plana vitrectomy. Acta ophthalmologica Scandinavica, 2007, Volume: 85, Issue:6 Topics: Aged; Anti-Inflammatory Agents; Connective Tissue; Double-Blind Method; Endophthalmitis; Female; Hum	2007
Rimexolone 1% versus prednisolone acetate in preventing early postoperative inflammation after cataract surgery. International ophthalmology, 2008, Volume: 28, Issue:4 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anterior Chamber; Anti-Inflammatory Agents; Cataract Ext	2008
[Use and limits of preventive antilymphocyte globulin therapy following kidney transplantation. A prospective randomized study]. Klinische Wochenschrift, 1984, Oct-15, Volume: 62, Issue:20 Topics: Antilymphocyte Serum; Azathioprine; Cadaver; Clinical Trials as Topic; Drug Therapy, Combination; Gr	1984
High versus "low" dose corticosteroids in recipients of cadaveric kidneys: prospective controlled trial. British medical journal (Clinical research ed.), 1983, Apr-02, Volume: 286, Issue:6371 Topics: Adolescent; Adult; Azathioprine; Cadaver; Clinical Trials as Topic; Creatinine; Drug Therapy, Combin	1983
Phase III study of FK 506 in kidney transplantation. Japanese FK 506 Study Group. Transplantation proceedings, 1995, Volume: 27, Issue:1 Topics: Bacterial Infections; Blood Pressure; Cadaver; Cyclosporine; Drug Monitoring; Drug Therapy, Combinat	1995
[Is subconjunctival steroid administration in addition to local therapy after cataract operations necessary? A laser tyndallometric study]. Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1995, Volume: 92, Issue:3 Topics: Aged; Aged, 80 and over; Cataract Extraction; Conjunctiva; Dexamethasone; Drug Administration Schedu	1995
[Monotherapy vs combination therapy with topical prednisolone and indomethacin]. Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1995, Volume: 92, Issue:1 Topics: Aged; Blood-Retinal Barrier; Cataract Extraction; Drug Therapy, Combination; Female; Humans; Indomet	1995
Safety of urgent restorative proctocolectomy with ileal pouch-anal anastomosis for fulminant colitis. Diseases of the colon and rectum, 1995, Volume: 38, Issue:4 Topics: Acute Disease; Adolescent; Adult; Aged; Algorithms; Anti-Bacterial Agents; Child; Child, Preschool;	1995
A comparison of topical diclofenac with prednisolone for postcataract inflammation. Archives of ophthalmology (Chicago, Ill. : 1960), 1995, Volume: 113, Issue:6 Topics: Administration, Topical; Anterior Chamber; Cataract Extraction; Cell Count; Diclofenac; Double-Blind	1995
Triple versus quadruple induction immunosuppression in pancreas transplantation. Transplantation proceedings, 1995, Volume: 27, Issue:1 Topics: Adult; Antilymphocyte Serum; Azathioprine; Communicable Diseases; Creatinine; Cyclosporine; Drug Res	1995
Coronary vasculopathy following cardiac transplantation and cyclosporine immunosuppression: preventive treatment with angiopeptin, a somatostatin analog. Transplantation proceedings, 1994, Volume: 26, Issue:5 Topics: Antilymphocyte Serum; Arteriosclerosis; Azathioprine; Coronary Disease; Cyclosporine; Female; Heart	1994
Corticosteroids in corneal graft rejection: double versus single pulse therapy. Cornea, 1994, Volume: 13, Issue:5 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Corneal Transplantation; Drug Therapy, Combination; Fema	1994
[Anti-inflammatory effect of a local combination therapy with diclofenac and prednisolone vs. indomethacin and prednisolone. A laser flare cell photometry study]. Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1994, Volume: 91, Issue:2 Topics: Aged; Aqueous Humor; Diclofenac; Dose-Response Relationship, Drug; Drug Administration Schedule; End	1994
Peroperative prednisolone fails to improve the clinical outcome following surgery for prolapsed lumbar intervertebral disc. A randomized controlled trial. Scandinavian journal of rheumatology, 1994, Volume: 23, Issue:1 Topics: Adult; Aged; Arachnoiditis; Double-Blind Method; Female; Humans; Intervertebral Disc Displacement; L	1994
A comparison of topical non-steroidal anti-inflammatory drugs to steroids for control of post cataract inflammation. Insight (American Society of Ophthalmic Registered Nurses), 1993, Volume: 18, Issue:1 Topics: Cataract Extraction; Diclofenac; Eye Diseases; Humans; Inflammation; Lenses, Intraocular; Postoperat	1993
Comparison of OKT3 and antithymocyte globulin as induction immunosuppressive agents in renal transplantation. Transplantation proceedings, 1996, Volume: 28, Issue:3 Topics: Adolescent; Adult; Aged; Antilymphocyte Serum; Azathioprine; Child; Creatinine; Cyclosporine; Female	1996
Long-term comparison of tacrolimus and cyclosporine-based immunosuppression in kidney recipients with grafts from non-heart-beating cadaver donor. Transplantation proceedings, 1998, Volume: 30, Issue:4 Topics: Adolescent; Adult; Blood Transfusion; Cadaver; Cyclosporine; Female; Follow-Up Studies; Graft Reject	1998
Tacrolimus/mycophenolate mofetil/steroid-based immunosuppression after pancreas-kidney transplantation with single shot antithymocyte globulin. Transplantation proceedings, 1998, Volume: 30, Issue:4 Topics: Adult; Antilymphocyte Serum; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Drug Therapy, Combin	1998
A randomized double-masked trial comparing ketorolac tromethamine 0.5%, diclofenac sodium 0.1%, and prednisolone acetate 1% in reducing post-phacoemulsification flare and cells. Ophthalmic surgery and lasers, 1998, Volume: 29, Issue:7 Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; C	1998
The efficacy and safety of diclofenac 0.1% versus prednisolone acetate 1% following trabeculectomy with adjunctive mitomycin-C. Ophthalmic surgery and lasers, 1998, Volume: 29, Issue:7 Topics: Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Chemotherapy, Adjuvant; Chr	1998
A randomized clinical trial of the nonsteroidal eyedrop diclofenac after strabismus surgery. Ophthalmology, 1998, Volume: 105, Issue:8 Topics: Administration, Topical; Adolescent; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroid	1998
Postoperative systemic corticosteroid treatment and Molteno implant surgery: a randomized clinical trial. Acta ophthalmologica Scandinavica, 1999, Volume: 77, Issue:1 Topics: Administration, Oral; Adult; Aged; Biomarkers; Drug Administration Schedule; Female; Filtering Surge	1999
Comparison of the efficacy and safety of ketorolac tromethamine 0.5% and prednisolone acetate 1% after cataract surgery. Journal of cataract and refractive surgery, 1999, Volume: 25, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; C	1999
Topical intrastromal steroid during laser in situ keratomileusis to retard interface keratitis. Journal of cataract and refractive surgery, 1999, Volume: 25, Issue:11 Topics: Administration, Topical; Adult; Astigmatism; Corneal Stroma; Follow-Up Studies; Glucocorticoids; Hum	1999
Comparison of the safety and efficacy of mycophenolate mofetil, prednisolone and cyclosporine and conventional cyclosporine and prednisolone in kidney transplantation. Transplantation proceedings, 2000, Volume: 32, Issue:7 Topics: Adrenal Cortex Hormones; Biopsy; Cyclosporine; Drug Therapy, Combination; Female; Gastrointestinal D	2000
Initial experience of combined immunosuppressive induction therapy with polyclonal antithymocyte antibody, FK 506 (tacrolimus), and prednisolone in clinical liver transplantation. Transplantation proceedings, 2000, Volume: 32, Issue:8 Topics: Adult; Aged; Antilymphocyte Serum; Drug Therapy, Combination; Follow-Up Studies; Humans; Immunosuppr	2000
[The use of predforte in the transnasal endoscopic sinus surgery]. Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology, 1998, Volume: 12, Issue:5 Topics: Adolescent; Adult; Aged; Endoscopy; Female; Humans; Male; Maxillary Sinusitis; Middle Aged; Paranasa	1998
Antilymphocyte globulins versus OKT3 as prophylactic treatment in highly sensitized renal transplant recipients. Transplant international : official journal of the European Society for Organ Transplantation, 1994, Volume: 7 Suppl 1 Topics: Adult; Aged; Antibodies; Antilymphocyte Serum; Azathioprine; Cyclosporine; Drug Therapy, Combination	1994
Mycofenolate mofetil-cyclosporine immunosuppression of kidney transplantation recipients with two different corticosteroid doses. Transplantation proceedings, 2001, Volume: 33, Issue:3 Topics: Adrenal Cortex Hormones; Cyclosporine; Diabetes Mellitus; Dose-Response Relationship, Drug; Drug The	2001
Quadruple versus dual tacrolimus-based induction after liver transplantation: a prospective, randomized trial. Transplantation proceedings, 2001, Volume: 33, Issue:3 Topics: Antilymphocyte Serum; Azathioprine; Bacterial Infections; Cytomegalovirus Infections; Drug Therapy,	2001
beta-herpesvirus activation after kidney transplantation with mycophenolate mofetil-based maintenance immunosuppression. Transplantation proceedings, 2001, Volume: 33, Issue:3 Topics: Adult; Azathioprine; Cyclosporine; Cytomegalovirus; Cytomegalovirus Infections; Drug Therapy, Combin	2001
Comparison of 0.1% dexamethasone phosphate eye gel (Dexagel) and 1% prednisolone acetate eye suspension in the treatment of post-operative inflammation after cataract surgery. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2001, Volume: 239, Issue:10 Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Dexamethasone; Dr	2001
Improved efficacy of basiliximab over antilymphocyte globulin induction therapy in paediatric renal transplantation. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2002, Volume: 17, Issue:7 Topics: Antibodies, Monoclonal; Antilymphocyte Serum; Azathioprine; Basiliximab; Child; Cyclosporine; Drug T	2002
Double-blind study of prednisolone and papase as inhibitors of complications after oral surgery. Journal of the American Dental Association (1939), 1976, Volume: 93, Issue:2 Topics: Clinical Trials as Topic; Edema; Humans; Mouth; Pain; Papain; Placebos; Postoperative Complications;	1976
Sri Lankan experience with three immunosuppressive protocols in living related donor kidney transplantation. Transplantation proceedings, 1992, Volume: 24, Issue:5 Topics: Acute Disease; Azathioprine; Costs and Cost Analysis; Cyclosporine; Family; Follow-Up Studies; Graft	1992
High incidence of significant bacteriuria in kidney graft recipients with triple therapy. Transplantation proceedings, 1992, Volume: 24, Issue:1 Topics: Australia; Azathioprine; Bacteriuria; Cyclosporine; Female; Humans; Immunosuppression Therapy; Incid	1992
[Differential treatment of postoperative and uveitis-induced inflammatory cystoid macular edema]. Klinische Monatsblatter fur Augenheilkunde, 1992, Volume: 200, Issue:5 Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Diclofenac; Female; Humans; Injections; Lenses, Intra	1992
Renal cadaveric transplantation in diabetics using total lymphoid irradiation or cyclosporin A. A controlled randomized study. Leuven Collaborative Transplantation Group. Transplant international : official journal of the European Society for Organ Transplantation, 1988, Volume: 1, Issue:2 Topics: Adult; Bacterial Infections; Cyclosporins; Diabetic Nephropathies; Female; Graft Rejection; Graft Su	1988
Cyclosporine mono-drug therapy. Transplantation proceedings, 1988, Volume: 20, Issue:3 Suppl 3 Topics: Azathioprine; Communicable Diseases; Cyclosporins; Drug Therapy, Combination; Graft Survival; Humans	1988
Prednisolone acetate-gentamicin combination following cataract surgery. Annals of ophthalmology, 1987, Volume: 19, Issue:7 Topics: Adult; Aged; Cataract Extraction; Clinical Trials as Topic; Drug Combinations; Female; Gentamicins;	1987
Renal transplantation without steroids. The Journal of pediatrics, 1987, Volume: 111, Issue:6 Pt 2 Topics: Clinical Trials as Topic; Cyclosporins; Drug Therapy, Combination; Female; Graft Survival; Humans; K	1987
Double-blind controlled trial to compare anti-inflammatory effects of tolmetin 2%, prednisolone 0.5%, and placebo in post-cataract extraction eyes. The British journal of ophthalmology, 1986, Volume: 70, Issue:10 Topics: Cataract Extraction; Clinical Trials as Topic; Double-Blind Method; Endophthalmitis; Humans; Middle	1986
[One year experience with cyclosporin A in clinical heart transplantation]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1985, Mar-10, Volume: 105, Issue:7 Topics: Adult; Clinical Trials as Topic; Cyclosporins; Female; Graft Rejection; Heart Transplantation; Human	1985
Short- and long-term effects of postoperative corticosteroids on trabeculectomy. Ophthalmology, 1985, Volume: 92, Issue:7 Topics: Adult; Aged; Combined Modality Therapy; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure	1985
[Large intravenous doses of cortisone in renal transplantation]. Wiener medizinische Wochenschrift (1946), 1974, Volume: 124, Issue:15 Topics: Adolescent; Adult; Azathioprine; Child; Diabetes Mellitus; Gastrointestinal Hemorrhage; Graft vs Hos	1974
[Effects of drugs on the inflammatory-fibroplastic processes in urologic diseases and uroplastic surgery]. Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1972, Dec-26, Volume: 61, Issue:52 Topics: Adult; Clinical Trials as Topic; Drug Combinations; Female; Humans; Inflammation; Male; Oxyphenbutaz	1972
[A study of the function of the adrenal cortex in patients after cholecystectomy]. Vestnik khirurgii imeni I. I. Grekova, 1967, Volume: 98, Issue:2 Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Adult; Aged; Biliary Fistula; Bronchitis	1967

prednisolone and Complication, Postoperative

Research Excerpts

Research

Studies (559)

Authors

Clinical Trials (16)

Trial Overview

Trial Outcomes

Early Development of Scarring in the Grafts

Graft Function: Level of Creatinine

Graft Survival Censored for Death With Function

Initial Length of Stay in Hospital

Occurrence of Rejection Episodes

Occurrence of Significant Episodes of Infection

One Year Survival With a Functioning Graft

Patient Survival Censored for Death With Function

Change in Renal Function as Measured by Serum Creatinine, Stratified by Withdrawal Status

Number of Acute Rejections Between Initiation of Sirolimus Withdrawal and End of Study

Number of Acute Rejections in All Enrolled Participants

Number of Acute Rejections in All Enrolled Participants Following Sirolimus Withdrawal

Number of Alemtuzumab Associated Adverse Events, Stratified by Sirolimus Withdrawal Status

Number of Deaths Stratified by Sirolimus Withdrawal Status

Number of Participants Requiring Anti-lymphocyte Therapy for an Acute Rejection, Stratified by Sirolimus Withdrawal Status

Number of Participants Who Experienced Graft Loss Stratified by Sirolimus Withdrawal Status

Number of Severe Acute Rejections Stratified by Sirolimus Withdrawal Status

Number of Side Effects of Conventional Immunosuppression, Stratified by Withdrawal Status

Number of Sirolimus Associated Adverse Events, Stratified by Sirolimus Withdrawal Status

Number of Tacrolimus Associated Adverse Events, Stratified by Sirolimus Withdrawal Status

Time From Transplantation to Acute Rejection in Participants for Whom Acute Rejection Occurred During the 1 Year Post-transplant Period

Time From Transplantation to Acute Rejection in Participants for Whom Sirolimus Withdrawal Was Not Initiated

The Proportion of Participants With Graft Loss or Death Within 12 Months Post Kidney Transplantation

Response to Leucine in Transfusion Dependent Patients With Diamond Blackfan Anemia

Reviews

Trials

Other Studies

Intervention	Participants (Count of Participants)
	Complete Hematologic Response	Partial hematologic response	No hematologic response	Progression
Leucine	2	5	36	0

Authors	Studies
Valvecchia, G	1
Kaufer, R	1
Ferroni, C	1
Zaldívar, R	1
Masseroni, M	1
Idiart, C	1
Ferroni, V	1
Marino, F	1
Nuñez, M	1
Del Papa, M	1
Passerini, MS	1
Hovanesian, JA	1
Donnenfeld, ED	1
Kazemi, K	1
Hosseinzadeh, A	1
Shahriarirad, R	1
Nikeghbalian, S	1
Kamran, H	1
Hosseinpour, P	1
Tanideh, N	1
Jamshidi, K	1
Lu, AQ	1
Rizk, M	1
O'Rourke, T	1
Goodling, K	1
Lehman, E	1
Scott, IU	2
Pantanelli, SM	1
Karatas Durusoy, G	1
Gümüş, G	1
Öcal, MC	1
Kara, N	1
Raina, UK	1
Ravinesh, K	1
Bhattacharya, S	1
Pavitra, B	1
Thakar, M	1
Mundisugih, J	1
Fernando, H	2
Bergin, P	1