Page last updated: 2024-11-06

prednisolone and Chronic Primary Open Angle Glaucoma

prednisolone has been researched along with Chronic Primary Open Angle Glaucoma in 37 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Research Excerpts

ExcerptRelevanceReference
"Patients older than 18 years with intraocular pressure (IOP) of more than 18 mmHg for whom the clinician decided SLT was the appropriately indicated therapy were randomized to 1 of 3 groups in a ratio of 1:1:1 as follows: ketorolac 0."5.30SALT Trial: Steroids after Laser Trabeculoplasty: Impact of Short-Term Anti-inflammatory Treatment on Selective Laser Trabeculoplasty Efficacy. ( Albeiruti, E; Fajardo, R; Goldberg, JL; Groth, SL; Loewen, N; Nunez, M; Schuman, JS; Sharpsten, L, 2019)
"To determine whether a topical ophthalmic diclofenac sodium formulation containing a proprietary polymeric drug delivery system (ISV-205), when dosed concomitantly with 1% prednisolone acetate, is effective in blocking the intraocular pressure (IOP) response in humans."5.10Prevention of corticosteroid-induced intraocular pressure elevation using ISV-205. ( Stewart, WC, 2003)
"In the diclofenac group (n = 14), the preoperative intraocular pressure of 30."5.08The efficacy and safety of diclofenac 0.1% versus prednisolone acetate 1% following trabeculectomy with adjunctive mitomycin-C. ( Cate, EA; Dubiner, HB; Kent, AR; Mundorf, TK; Stewart, JA; Stewart, WC; Whitaker, R, 1998)
"A randomized, prospective study on 68 eyes of 54 patients with progressive, uncontrolled, noninflammatory open-angle glaucoma showed that eyes that received topical prednisolone 1% had a lower intraocular pressure (IOP) 18 months following trabeculectomy than the eyes that received no prednisolone."5.07The effects of postoperative corticosteroids on trabeculectomy and the clinical course of glaucoma: five-year follow-up study. ( Birbillis, EM; Roth, SM; Spaeth, GL; Starita, RJ; Steinmann, WC, 1991)
"The case concerns an 81-year-old woman on treatment with a topical fixed combination of timolol and brimonidine who was diagnosed in the Emergency Department with acute anterior granulomatous hypertensive uveitis."3.88Hypertensive acute granulomatous anterior uveitis as a side effect of topical brimonidine. ( Arciniegas-Perasso, CA; Clemente-Tomás, R; Duch-Samper, AM; García-Ibor, F; Hervás-Hernandis, JM; Ruiz-Del Río, N, 2018)
"0% prednisolone acetate before performing argon laser trabeculoplasty in an attempt to prevent the increase in intraocular pressure frequently observed during the immediate postoperative period."3.66Effects of corticosteroid pretreatment on argon laser trabeculoplasty. ( Ruderman, JM; Weinreb, RN; Wilensky, JT; Zweig, KO, 1983)
"The intraocular pressures were measured at regular intervals during the 6-months follow-up period."2.80Influence on intraocular pressure of anti-inflammatory treatments after selective laser trabeculoplasty. ( Anctil, JL; Champagne, S; Des Marchais, B; Goyette, A; Lajoie, C, 2015)
"A 35-year-old myopic man with juvenile open angle glaucoma was referred to us with fluctuating intraocular pressure (IOP) and progression in his only seeing left eye."1.42Restoration of pretrabeculectomy visual acuity and a functioning filtering bleb in an eye with delayed suprachoroidal haemorrhage following trabeculectomy. ( Balijepalli, P; Gupta, S; Senthil, S, 2015)
"Mild anterior uveitis is an unfamiliar adverse effect of pamidronate therapy."1.34Bilateral severe fibrinous anterior uveitis--an unusual complication of pamidronate therapy exacerbated by topical latanoprost. ( Palimar, P; Quah, S; Ramasamy, B; Sahni, JN, 2007)
"All nine eyes had recurrence of the membranes after treatment terminated and required a maintenance regimen of corticosteroid eyedrops."1.29Reduced vision secondary to pigmented cellular membranes on silicone intraocular lenses. ( Barad, JP; Carlson, DW; Parsons, MR, 1995)
"The clinical course was like chronic open angle glaucoma in 25 eyes, and 1 eye simulated an acute glaucoma attack."1.29[Clinical analysis of steroid glaucoma]. ( Kong, LX, 1993)
"The intraocular pressure was reduced to about 6 mm Hg in treated eyes from an average pressure of 26 mm Hg."1.28[Anti-inflammatory treatment after argon laser trabeculoplasty]. ( Bleckmann, H; Garus, HJ; Huk, B, 1991)

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19904 (10.81)18.7374
1990's10 (27.03)18.2507
2000's7 (18.92)29.6817
2010's14 (37.84)24.3611
2020's2 (5.41)2.80

Authors

AuthorsStudies
Groth, SL1
Albeiruti, E1
Nunez, M1
Fajardo, R1
Sharpsten, L1
Loewen, N1
Schuman, JS1
Goldberg, JL1
Ilveskoski, L1
Taipale, C1
Tuuminen, R1
Pareja-Ríos, A1
Bonaque-González, S1
Clemente-Tomás, R1
Arciniegas-Perasso, CA1
Hervás-Hernandis, JM1
García-Ibor, F1
Ruiz-Del Río, N1
Duch-Samper, AM1
Nazarali, S1
Cote, SL1
Gooi, P1
Rueda-Rueda, T1
Sánchez-Vicente, LJ1
Moruno-Rodríguez, A1
Monge-Esquivel, J1
Muñoz-Morales, A1
López-Herrero, F1
Jinapriya, D1
D'Souza, M1
Hollands, H1
El-Defrawy, SR1
Irrcher, I1
Smallman, D1
Farmer, JP1
Cheung, J1
Urton, T1
Day, A1
Sun, X1
Campbell, RJ1
Champagne, S1
Anctil, JL1
Goyette, A1
Lajoie, C1
Des Marchais, B1
Cherof, AM1
SooHoo, JR1
Kahook, MY1
Seibold, LK1
Senthil, S1
Gupta, S1
Balijepalli, P1
Huang, OS1
Mehta, JS1
Htoon, HM1
Tan, DT1
Wong, TT1
AlKheraiji, NF1
AlKheraiji, AF1
Stone, DU1
Asensio-Sánchez, VM1
Spiga, MG1
Borrás, T1
Holz, H1
Pirouzian, A1
Danias, J1
Gerometta, R1
Ge, Y1
Ren, L1
Panagis, L1
Mittag, TW1
Candia, OA1
Podos, SM1
Koktekir, BE1
Gedik, S1
Bakbak, B1
Stewart, WC2
Satav, SS1
Thomas, R1
Kahana, A1
Chiang, MY1
Shah, P1
Ramasamy, B1
Quah, S1
Sahni, JN1
Palimar, P1
Ruderman, JM1
Zweig, KO1
Wilensky, JT1
Weinreb, RN1
Carlson, DW1
Barad, JP1
Parsons, MR1
Kong, LX1
Bartlett, JD1
Woolley, TW1
Adams, CM1
Kong, L1
Zhang, C1
Chen, M1
Xue, G1
Araujo, SV1
Spaeth, GL3
Roth, SM2
Starita, RJ3
Kent, AR1
Dubiner, HB1
Whitaker, R1
Mundorf, TK1
Stewart, JA1
Cate, EA1
Fechtner, RD1
Khouri, AS1
Zimmerman, TJ1
Bullock, J1
Feldman, R1
Kulkarni, P1
Michael, AJ1
Realini, T1
Warwar, R1
Goela, A1
Damji, KF1
Daneshvar, H1
Gilberg, SM1
Wu, G1
Morrell, A1
Huk, B1
Garus, HJ1
Bleckmann, H1
Birbillis, EM1
Steinmann, WC1
McDonnell, PJ1
Kerr Muir, MG1
Călugăru, M1
Fellman, RL1
Poryzees, EM1
Greenidge, KC1
Traverso, CE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective, Multi-center, Controlled, Double-blind Study to Evaluate the Efficacy and Tolerability of a Steroid/Antibiotic Associated Treatment Following Cataract Extraction by Means of Phaco-emulsification[NCT02973880]Phase 3180 participants (Actual)Interventional2017-10-15Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

10 trials available for prednisolone and Chronic Primary Open Angle Glaucoma

ArticleYear
SALT Trial: Steroids after Laser Trabeculoplasty: Impact of Short-Term Anti-inflammatory Treatment on Selective Laser Trabeculoplasty Efficacy.
    Ophthalmology, 2019, Volume: 126, Issue:11

    Topics: Administration, Ophthalmic; Aged; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Fema

2019
Anti-inflammatory Medication of Cataract Surgery in Pseudoexfoliation Syndrome - NSAID Is Needed.
    Current eye research, 2020, Volume: 45, Issue:7

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Benzeneacetamides; Double-Blind Me

2020
Anti-inflammatory therapy after selective laser trabeculoplasty: a randomized, double-masked, placebo-controlled clinical trial.
    Ophthalmology, 2014, Volume: 121, Issue:12

    Topics: Aged; Aged, 80 and over; Analysis of Variance; Anti-Inflammatory Agents; Cross-Sectional Studies; Do

2014
Influence on intraocular pressure of anti-inflammatory treatments after selective laser trabeculoplasty.
    Journal francais d'ophtalmologie, 2015, Volume: 38, Issue:7

    Topics: Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Combined Modalit

2015
Prevention of corticosteroid-induced intraocular pressure elevation using ISV-205.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2003, Volume: 121, Issue:11

    Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; D

2003
Identification of high intraocular pressure responders to topical ophthalmic corticosteroids.
    Journal of ocular pharmacology, 1993,Spring, Volume: 9, Issue:1

    Topics: Adult; Circadian Rhythm; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Ag

1993
A ten-year follow-up on a prospective, randomized trial of postoperative corticosteroids after trabeculectomy.
    Ophthalmology, 1995, Volume: 102, Issue:12

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Female; Follow-Up Studies; Glaucoma, Angle-

1995
The efficacy and safety of diclofenac 0.1% versus prednisolone acetate 1% following trabeculectomy with adjunctive mitomycin-C.
    Ophthalmic surgery and lasers, 1998, Volume: 29, Issue:7

    Topics: Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Chemotherapy, Adjuvant; Chr

1998
The effects of postoperative corticosteroids on trabeculectomy and the clinical course of glaucoma: five-year follow-up study.
    Ophthalmic surgery, 1991, Volume: 22, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Female; Follow-Up Studies; Glaucoma, Angle-Closure; Glaucoma, Open-A

1991
Short- and long-term effects of postoperative corticosteroids on trabeculectomy.
    Ophthalmology, 1985, Volume: 92, Issue:7

    Topics: Adult; Aged; Combined Modality Therapy; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure

1985

Other Studies

27 other studies available for prednisolone and Chronic Primary Open Angle Glaucoma

ArticleYear
Late Corneal Stromal Deposits After COVID-19.
    Cornea, 2021, 08-01, Volume: 40, Issue:8

    Topics: Corneal Diseases; Corneal Stroma; COVID-19; COVID-19 Drug Treatment; COVID-19 Nucleic Acid Testing;

2021
Hypertensive acute granulomatous anterior uveitis as a side effect of topical brimonidine.
    Archivos de la Sociedad Espanola de Oftalmologia, 2018, Volume: 93, Issue:10

    Topics: Acute Disease; Adrenergic alpha-2 Receptor Agonists; Aged, 80 and over; Brimonidine Tartrate; Conjun

2018
Gonioscopy-Assisted Transluminal Trabeculotomy (GATT) in Postpenetrating Keratoplasty Steroid-induced Glaucoma: A Case Report.
    Journal of glaucoma, 2018, Volume: 27, Issue:10

    Topics: Adult; Follow-Up Studies; Glaucoma, Open-Angle; Glucocorticoids; Gonioscopy; Humans; Intraocular Pre

2018
Bilateral acute iris depigmentation and bilateral acute iris transillumination syndrome.
    Archivos de la Sociedad Espanola de Oftalmologia, 2019, Volume: 94, Issue:7

    Topics: Acute Disease; Adult; Antihypertensive Agents; Diagnosis, Differential; Drug Therapy, Combination; E

2019
Endophthalmitis With Corneal Infiltrate After EX-PRESS Glaucoma Drainage Device Implantation.
    Journal of glaucoma, 2016, Volume: 25, Issue:3

    Topics: Alkylating Agents; Anti-Bacterial Agents; Corneal Diseases; Device Removal; Drug Combinations; Endop

2016
Restoration of pretrabeculectomy visual acuity and a functioning filtering bleb in an eye with delayed suprachoroidal haemorrhage following trabeculectomy.
    BMJ case reports, 2015, Dec-09, Volume: 2015

    Topics: Adult; Blister; Choroid Hemorrhage; Glaucoma, Open-Angle; Glucocorticoids; Humans; Male; Mydriatics;

2015
Incidence and Risk Factors of Elevated Intraocular Pressure Following Deep Anterior Lamellar Keratoplasty.
    American journal of ophthalmology, 2016, Volume: 170

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Corneal Transplantation; Cyclosporine; Dexamethasone

2016
Mycobacterium abscessus scleritis after a Baerveldt glaucoma implant.
    Clinical & experimental ophthalmology, 2017, Volume: 45, Issue:3

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Ceftazidime; Chronic Disease; Drug Therapy, Combina

2017
[Toxic epidermal necrolysis following dorzolamide eyedrops].
    Anales de medicina interna (Madrid, Spain : 1984), 2008, Volume: 25, Issue:1

    Topics: Aged; Critical Care; Drug Therapy, Combination; Eye Diseases; Female; Glaucoma, Open-Angle; Humans;

2008
Development of a gene therapy virus with a glucocorticoid-inducible MMP1 for the treatment of steroid glaucoma.
    Investigative ophthalmology & visual science, 2010, Volume: 51, Issue:6

    Topics: Adenoviridae; Adolescent; Aged; Blotting, Western; Cells, Cultured; Child, Preschool; Collagen; Dexa

2010
Bilateral diffuse lamellar keratitis following consecutive selective laser trabeculoplasty in LASIK patient.
    Journal of cataract and refractive surgery, 2010, Volume: 36, Issue:5

    Topics: Functional Laterality; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Keratitis; Keratomileusis

2010
Gene expression changes in steroid-induced IOP elevation in bovine trabecular meshwork.
    Investigative ophthalmology & visual science, 2011, Nov-07, Volume: 52, Issue:12

    Topics: Animals; Anti-Inflammatory Agents; Cattle; Computational Biology; Disease Models, Animal; Female; Ge

2011
Bilateral severe anterior uveitis after unilateral selective laser trabeculoplasty.
    Clinical & experimental ophthalmology, 2013, Volume: 41, Issue:3

    Topics: Adult; Anterior Chamber; Cyclopentolate; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Gl

2013
Preventing steroid-induced glaucoma.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2005, Volume: 123, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Glaucoma, Open-Angle; Glucocorticoids; Humans;

2005
Prevention of steroid-induced intraocular pressure elevation.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2005, Volume: 123, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cytoskeletal Proteins; Diclofenac; Drug Delivery Systems; E

2005
Nasal septal perforation enlargement related to topical ocular steroids.
    British journal of clinical pharmacology, 2005, Volume: 60, Issue:6

    Topics: Female; Glaucoma, Open-Angle; Glucocorticoids; Humans; Middle Aged; Nasal Septum; Nose Diseases; Oph

2005
Bilateral severe fibrinous anterior uveitis--an unusual complication of pamidronate therapy exacerbated by topical latanoprost.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2007, Volume: 23, Issue:5

    Topics: Acute Disease; Administration, Topical; Aged, 80 and over; Anti-Inflammatory Agents; Bone Density Co

2007
Effects of corticosteroid pretreatment on argon laser trabeculoplasty.
    American journal of ophthalmology, 1983, Volume: 96, Issue:1

    Topics: Administration, Topical; Adrenal Cortex Hormones; Aged; Anti-Inflammatory Agents; Female; Glaucoma,

1983
Reduced vision secondary to pigmented cellular membranes on silicone intraocular lenses.
    American journal of ophthalmology, 1995, Volume: 120, Issue:4

    Topics: Aged; Aged, 80 and over; Cell Membrane; Female; Foreign-Body Reaction; Glaucoma, Open-Angle; Glucoco

1995
[Clinical analysis of steroid glaucoma].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 1993, Volume: 29, Issue:3

    Topics: Adolescent; Adult; Conjunctivitis; Dexamethasone; Female; Glaucoma, Open-Angle; Humans; Iritis; Male

1993
Clinical analysis of steroid glaucoma.
    Yan ke xue bao = Eye science, 1995, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Anti-Inflammatory Agents; Conjunctivitis, Allergic; Dexamethasone; Female; Follow

1995
Anterior uveitis associated with latanoprost.
    American journal of ophthalmology, 1998, Volume: 126, Issue:1

    Topics: Administration, Topical; Adult; Aged; Female; Glaucoma, Open-Angle; Glucocorticoids; Humans; Intraoc

1998
Delayed, recurrent hypotonous maculopathy following aqueous suppressant therapy in pseudophakia.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1999, Volume: 34, Issue:7

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Drug Therapy, Combination; Female; Glaucoma, A

1999
Severe hypotony following cataract extraction in a patient on latanoprost.
    Eye (London, England), 2000, Volume: 14, Issue:Pt 6

    Topics: Aged; Anti-Inflammatory Agents; Antihypertensive Agents; Choroid Diseases; Glaucoma, Open-Angle; Hum

2000
[Anti-inflammatory treatment after argon laser trabeculoplasty].
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1991, Volume: 203, Issue:1

    Topics: Aged; Anterior Chamber; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Endophth

1991
Glaucoma associated with systemic corticosteroid therapy.
    Lancet (London, England), 1985, Aug-17, Volume: 2, Issue:8451

    Topics: Adult; Glaucoma, Open-Angle; Humans; Male; Prednisolone

1985
[Genetic aspects in hypertensive uveitis].
    Journal francais d'ophtalmologie, 1986, Volume: 9, Issue:2

    Topics: Acute Disease; Aged; Cortisone; Glaucoma; Glaucoma, Open-Angle; Humans; Middle Aged; Ocular Hyperten

1986