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prednisolone and Central Nervous System Neoplasm

prednisolone has been researched along with Central Nervous System Neoplasm in 24 studies

Prednisolone: A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.
prednisolone : A glucocorticoid that is prednisone in which the oxo group at position 11 has been reduced to the corresponding beta-hydroxy group. It is a drug metabolite of prednisone.

Research Excerpts

ExcerptRelevanceReference
"Although high-dose methotrexate and whole-brain radiation therapy (WBRT) is the current standard for primary central nervous system lymphoma (PCNSL), it has a limited response rate and produces radiation-induced neurotoxicity."7.80Reduced neurotoxicity with combined treatment of high-dose methotrexate, cyclophosphamide, doxorubicin, vincristine and prednisolone (M-CHOP) and deferred radiotherapy for primary central nervous system lymphoma. ( Date, I; Ichikawa, T; Ishida, J; Kawasaki, A; Kondo, E; Kurozumi, K; Maeda, Y; Michiue, H, 2014)
"Although high-dose methotrexate and whole-brain radiation therapy (WBRT) is the current standard for primary central nervous system lymphoma (PCNSL), it has a limited response rate and produces radiation-induced neurotoxicity."3.80Reduced neurotoxicity with combined treatment of high-dose methotrexate, cyclophosphamide, doxorubicin, vincristine and prednisolone (M-CHOP) and deferred radiotherapy for primary central nervous system lymphoma. ( Date, I; Ichikawa, T; Ishida, J; Kawasaki, A; Kondo, E; Kurozumi, K; Maeda, Y; Michiue, H, 2014)
"Prednisolone (PRED) was given at the fixed dose of 60 mg/m(2) (IV or orally) on days 1-5."2.79A phase 1 dose escalation study of idarubicin combined with methotrexate, vindesine, and prednisolone for untreated elderly patients with primary central nervous system lymphoma. The GOELAMS LCP 99 trial. ( Brion, A; Chabin, M; Clavert, A; Colombat, P; Cumin, I; Delwail, V; Escoffre-Barbe, M; Gardembas, M; Ingrand, P; Lacotte-Thierry, L; Legouffe, E; Olivier, G; Solal-Celigny, P, 2014)
"He was diagnosed with stage II Hodgkin's lymphoma at the age of 15, and we considered the possibility of newly emerged CNS lymphoma occurring in the immunosuppressive condition after the treatment of Hodgkin's lymphoma."2.52Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) after treatment for Hodgkin's lymphoma. ( Hirose, S; Mashima, K; Mori, T; Okamoto, S; Shimizu, T; Suzuki, N; Suzuki, S; Yamada, S, 2015)
"Superior sagittal sinus thrombosis (SSST) has been reported to be caused by coagulopathy following oral contraceptive therapy, DIC, infection around the sinus, compression from a tumor, infiltration of tumor, and an inherited deficiency of proteins C and S, but SSST associated with hematological malignancies and L-asparaginase (L-Asp) therapy is rare."1.33[Superior sagittal sinus thrombosis during remission induction therapy for acute lymphoblastic leukemia]. ( Iijima, K; Iki, S; Kida, M; Nakasone, H; Taoka, K; Urabe, A; Usuki, K; Yoshimi, A, 2006)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (25.00)18.2507
2000's6 (25.00)29.6817
2010's12 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anand, S1
Das, A1
Choudhury, SS1
Yamashita, A1
Tokuda, M1
Matsuo, M1
Irie, J1
Tateishi, Y1
Mutsukura, K1
Hentrich, M1
Hoffmann, C1
Mosthaf, F1
Müller, M1
Siehl, J1
Wyen, C1
Hensel, M1
Olivier, G1
Clavert, A1
Lacotte-Thierry, L1
Gardembas, M1
Escoffre-Barbe, M1
Brion, A1
Cumin, I1
Legouffe, E1
Solal-Celigny, P1
Chabin, M1
Ingrand, P1
Colombat, P1
Delwail, V1
Ichikawa, T1
Kurozumi, K1
Michiue, H1
Ishida, J1
Maeda, Y2
Kondo, E1
Kawasaki, A1
Date, I1
Ellin, F1
Landström, J1
Jerkeman, M1
Relander, T1
Mashima, K1
Suzuki, S1
Mori, T1
Shimizu, T1
Yamada, S1
Hirose, S1
Okamoto, S1
Suzuki, N1
Graves, TD1
Collins, GP1
Parry, A1
Hasegawa, D1
Manabe, A1
Ohara, A1
Kikuchi, A2
Koh, K1
Kiyokawa, N1
Fukushima, T1
Ishida, Y1
Saito, T1
Hanada, R1
Tsuchida, M1
Shimada, K1
Schmitz, N1
Zeynalova, S1
Glass, B1
Kaiser, U1
Cavallin-Stahl, E1
Wolf, M1
Haenel, M1
Loeffler, M1
Truemper, L1
Pfreundschuh, M1
Tomita, N1
Yokoyama, M1
Yamamoto, W1
Watanabe, R1
Shimazu, Y1
Masaki, Y1
Tsunoda, S1
Hashimoto, C1
Murayama, K1
Yano, T1
Okamoto, R1
Tamura, K1
Sato, K1
Sunami, K1
Shibayama, H1
Takimoto, R1
Ohshima, R1
Hatta, Y1
Moriuchi, Y1
Kinoshita, T1
Yamamoto, M1
Numata, A1
Ishigatsubo, Y1
Takeuchi, K1
Pels, H1
Schmidt-Wolf, IG1
Glasmacher, A1
Schulz, H1
Engert, A1
Diehl, V1
Zellner, A1
Schackert, G1
Reichmann, H1
Kroschinsky, F1
Vogt-Schaden, M1
Egerer, G1
Bode, U1
Schaller, C1
Deckert, M1
Fimmers, R1
Helmstaedter, C1
Atasoy, A1
Klockgether, T1
Schlegel, U1
Holtkamp, M1
Okuducu, AF1
Klingebiel, R1
Ploner, CJ1
Adde, M1
Enblad, G1
Hagberg, H1
Sundström, C1
Laurell, A1
Laack, NN1
Ballman, KV1
Brown, PB1
O'Neill, BP1
Yoshimi, A1
Taoka, K1
Nakasone, H1
Iijima, K1
Kida, M1
Iki, S1
Urabe, A1
Usuki, K1
Shimizu, I1
Ichikawa, N1
Yotsumoto, M1
Sumi, M1
Ueno, M1
Kobayashi, H1
Grześkowiak-Melanowska, J1
Skoczeń, S1
Armata, J1
Tanaka, S1
Sawada, N1
Kamio, M1
Mochizuki, T1
Matsumoto, K1
Kuriyama, M1
Ono, Y1
Kunishio, K1
Tamiya, T1
Furuta, T1
Ohmoto, T1
Bos, GM1
van Putten, WL1
van der Holt, B1
van den Bent, M1
Verdonck, LF1
Hagenbeek, A1
Wu, HG1
Kim, IH1
Ha, SW1
Park, CI1
Bang, YJ1
Huh, DS1
Cooper, DL1
Ginsberg, SS1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase II Trial of Irinotecan in Recurrent Glioma[NCT00003134]Phase 264 participants (Actual)Interventional1998-01-31Completed
Primary Central Nervous System Non-Hodgkins's Lymphoma (PCNSL): A Phase II Clinical Trial of Radiation Therapy and High Dose Corticosteroids for Elderly Patients (70 Years of Age and Older)[NCT00003278]Phase 228 participants (Actual)Interventional1998-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for prednisolone and Central Nervous System Neoplasm

ArticleYear
Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) after treatment for Hodgkin's lymphoma.
    International journal of hematology, 2015, Volume: 102, Issue:6

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Central Nervous System Neoplasms; Chr

2015
[Treatment strategy for central nervous system involvement in intravascular large B-cell lymphoma].
    Brain and nerve = Shinkei kenkyu no shinpo, 2011, Volume: 63, Issue:5

    Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; C

2011
Brief chemotherapy, involved field radiation therapy, and central nervous system prophylaxis for paranasal sinus lymphoma.
    Cancer, 1992, Jun-15, Volume: 69, Issue:12

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Central Nervous System

1992

Trials

5 trials available for prednisolone and Central Nervous System Neoplasm

ArticleYear
A phase 1 dose escalation study of idarubicin combined with methotrexate, vindesine, and prednisolone for untreated elderly patients with primary central nervous system lymphoma. The GOELAMS LCP 99 trial.
    American journal of hematology, 2014, Volume: 89, Issue:11

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Chemoradioth

2014
The utility of performing the initial lumbar puncture on day 8 in remission induction therapy for childhood acute lymphoblastic leukemia: TCCSG L99-15 study.
    Pediatric blood & cancer, 2012, Volume: 58, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Case-Control Studies; Central Nervous Sy

2012
Primary central nervous system lymphoma: results of a pilot and phase II study of systemic and intraventricular chemotherapy with deferred radiotherapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Dec-15, Volume: 21, Issue:24

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cyclo

2003
For which patients with aggressive non-Hodgkin's lymphoma is prophylaxis for central nervous system disease mandatory? Dutch HOVON Group.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1998, Volume: 9, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Neoplasms; Bone Marro

1998
Survival improvement with combined radio-chemotherapy in the primary central nervous system lymphomas.
    Journal of Korean medical science, 1999, Volume: 14, Issue:5

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Central Nervous

1999

Other Studies

16 other studies available for prednisolone and Central Nervous System Neoplasm

ArticleYear
Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) in limited cutaneous sclerosis: a rare disease combination.
    BMJ case reports, 2019, Jan-07, Volume: 12, Issue:1

    Topics: Adult; Brain Stem; Central Nervous System Diseases; Central Nervous System Neoplasms; Cerebellum; Ch

2019
[A case of secondary central nervous system lymphoma presenting marked hypoglycorrhachia].
    Rinsho shinkeigaku = Clinical neurology, 2019, Jun-22, Volume: 59, Issue:6

    Topics: Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Biomar

2019
Therapy of HIV-associated lymphoma-recommendations of the oncology working group of the German Study Group of Physicians in Private Practice Treating HIV-Infected Patients (DAGNÄ), in cooperation with the German AIDS Society (DAIG).
    Annals of hematology, 2014, Volume: 93, Issue:6

    Topics: Anti-HIV Agents; Antibiotic Prophylaxis; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Comb

2014
Reduced neurotoxicity with combined treatment of high-dose methotrexate, cyclophosphamide, doxorubicin, vincristine and prednisolone (M-CHOP) and deferred radiotherapy for primary central nervous system lymphoma.
    Clinical neurology and neurosurgery, 2014, Volume: 127

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cyclophospha

2014
Central nervous system relapse in peripheral T-cell lymphomas: a Swedish Lymphoma Registry study.
    Blood, 2015, Jul-02, Volume: 126, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Alemtuzumab; Antibodies, Monoclonal, Humanized; Antineoplastic Combi

2015
Richter's syndrome of the brain and the spinal cord.
    Journal of neurology, neurosurgery, and psychiatry, 2011, Volume: 82, Issue:8

    Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Central Nerv

2011
CNS disease in younger patients with aggressive B-cell lymphoma: an analysis of patients treated on the Mabthera International Trial and trials of the German High-Grade Non-Hodgkin Lymphoma Study Group.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2012, Volume: 23, Issue:5

    Topics: Adolescent; Adult; Age of Onset; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Che

2012
Central nervous system event in patients with diffuse large B-cell lymphoma in the rituximab era.
    Cancer science, 2012, Volume: 103, Issue:2

    Topics: Adolescent; Adrenal Glands; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived;

2012
Cerebral toxoplasmosis in a patient with common variable immunodeficiency.
    Neurology, 2004, Dec-14, Volume: 63, Issue:11

    Topics: Anemia, Hemolytic, Autoimmune; Antibodies, Protozoan; Antiprotozoal Agents; Biopsy; Brain; Central N

2004
Outcome for young high-risk aggressive B-cell lymphoma patients treated with CHOEP-14 and rituximab (R-CHOEP-14).
    Medical oncology (Northwood, London, England), 2006, Volume: 23, Issue:2

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antimetabolites, Antine

2006
Whole-brain radiotherapy and high-dose methylprednisolone for elderly patients with primary central nervous system lymphoma: Results of North Central Cancer Treatment Group (NCCTG) 96-73-51.
    International journal of radiation oncology, biology, physics, 2006, Aug-01, Volume: 65, Issue:5

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neop

2006
Whole-brain radiotherapy and high-dose methylprednisolone for elderly patients with primary central nervous system lymphoma: Results of North Central Cancer Treatment Group (NCCTG) 96-73-51.
    International journal of radiation oncology, biology, physics, 2006, Aug-01, Volume: 65, Issue:5

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neop

2006
Whole-brain radiotherapy and high-dose methylprednisolone for elderly patients with primary central nervous system lymphoma: Results of North Central Cancer Treatment Group (NCCTG) 96-73-51.
    International journal of radiation oncology, biology, physics, 2006, Aug-01, Volume: 65, Issue:5

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neop

2006
Whole-brain radiotherapy and high-dose methylprednisolone for elderly patients with primary central nervous system lymphoma: Results of North Central Cancer Treatment Group (NCCTG) 96-73-51.
    International journal of radiation oncology, biology, physics, 2006, Aug-01, Volume: 65, Issue:5

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neop

2006
[Superior sagittal sinus thrombosis during remission induction therapy for acute lymphoblastic leukemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2006, Volume: 47, Issue:12

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Central Nervous System Neoplasm

2006
Asian variant of intravascular lymphoma: aspects of diagnosis and the role of rituximab.
    Internal medicine (Tokyo, Japan), 2007, Volume: 46, Issue:17

    Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplas

2007
What is the best method of prevention of therapeutic failures in CNS in high risk retinoblastoma?
    Medical and pediatric oncology, 1997, Volume: 28, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Child, Preschool;

1997
[Long-term survivor (15 years) following central nervous system involvement in B-cell lymphoma].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1996, Volume: 37, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neoplasms; Cyclophosphamide;

1996
[Clinical study of primary central nervous system lymphoma: the role of chemotherapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:7

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Central Nervous System Neop

1997